Nuclear medicine specialist Daniela Oprea-Lager has been appointed Professor of Theranostics at Radboudumc / Radboud University. Her research focuses on the combination of diagnostics and treatment using radioactive substances, with particular interest for urological tumors, especially prostate cancer.
Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.
Cryoablation, the destruction of malignant cancer cells by freezing them, is increasingly becoming an alternative to having conventional lumpectomy for patients diagnosed with early-stage, localised, low-risk breast cancer. Findings from numerous recent clinical trials show that cancer recurrence rates are very low and are comparable to breast conservation surgery (BCS).
A premiere that brings hope for fertility restoration to men who underwent chemotherapy during childhood: Researchers reintroduced cryopreserved immature testicular tissue taken 16 years prior.
Treating patients with Hodgkin lymphoma with a different form of chemotherapy shows promise to reduce severe side effects, shorten hospital time and increase likelihood of recovering fertility.
PET/CT image analysis using artificial intelligence (AI) can predict the occurrence of interstitial lung disease, a serious side effect of immunotherapy in lung cancer, a new study shows.
The year: 2034. Breast cancer patients benefit from perfectly personalised diagnostics and therapies. The tedium of follow-up treatments is a thing of the past, thanks to AI, augmented reality and robotics. Just a tale from the realm of science fiction, or could this soon be clinical reality? At the annual meeting of the German Senologic Society, Prof Dr Marc Thill from the Agaplesion Markus…
To diagnose neuroblastoma in children, lengthy scans and anaesthesia are often required. A new PET/CT imaging technique could deliver faster results without sedation for the paediatric patients.
Radiology practices have a high volume of chest X-rays without clinically significant finding, which take up a lot of time. A new AI tool could improve workflows by providing an automatic report.
Sentinel lymph node biopsies can help detect breast cancer – but not every patient benefits from the procedure. New research finds that a simple EHR prompt can prevent unnecessary surgery.
When colorectal surgery was first performed with robotic assistance in 2014, the procedure was questioned about safety, efficacy, and outcomes. Today it is an established option. Well-trained surgeons use robotic surgical systems confidently. Numerous clinical studies have verified its intraoperative benefits for patients and surgeons alike, as well as very positive outcomes for patients.
Microbubbles in a contrast agent allows for ultrasound imaging of the finest vascular details. This is the working principle of a technique called ultrasound localization microscopy (ULM).
A new study suggests that tattoos could be a risk factor for cancer in the lymphatic system, or lymphoma. Now, the researchers underline the need for more research on the topic.
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
Papillary thyroid carcinoma (PTC) is often treated with surgical resection, which often comes with significant side effects. Now, a new study points to a minimally invasive alternative.
When treating oesophageal cancer, surgeons may have a preference towards either open surgery or keyhole techniques. Now, a study explored superiority of one over the other in terms of recovery time and complications.
A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.
Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.
An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.
Breast MRI is increasingly being used as a primary breast cancer screening exam for young women. It brings benefits in women with dense breasts, who are at an elevated risk of developing breast cancer. The technique is also being ordered as a supplemental screening exam following mammography or breast ultrasound for women of all ages at high risk. But use of breast MRI as a screening tool is…
A new breast imaging technique provides high sensitivity for detecting cancer while significantly reducing the likelihood of false positive results, according to a new study.
With a combination of radiomics and deep learning, researchers aim to noninvasively determine lymph node metastasis before surgery. This could lead to more accurate diagnosis and treatment strategies.
Contraception, wound healing, arthritis treatment: Here are three recent papers published in ACS journals that could expand the beneficial uses for nanoparticles, based on results in rats.
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
Diagnosing early-stage lung cancer with low-dose CT screening dramatically improves the long-term survival rate of cancer patients, a large-scale, 20-year international study shows.
A new device that acts like a GPS to locate and remove breast and lymph node tumors was tested for its safety and effectiveness in a feasibility study - with promising results.
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
A team of researchers has developed a visualisation tool that combines high-speed cameras and fluorescent injection to distinguish tumour tissue from normal tissue across cancer types.
In thyroid removal surgery, reliable discrimination between different tissues is crucial. US surgeons have evaluated how a new handheld device using mass spectrometry can assist them.
Researchers in France identified changes to the immune memory after infection with the Omicron BA.1 variant in thrice-vaccinated patients. The remodeling actually works to the patients' benefit.
Researchers have unveiled a key mechanism of breast cancer cells to infiltrate lymph nodes. The discovery may lead to new metastasis-blocking treatments and improve patients’ lives.
Lyme disease, the most common tick-transmitted bacterial infection in the world, is challenging to diagnose. Initial early-stage symptoms may include skin rash, fever, headache, fatigue, swollen lymph nodes, and/or body and joint aches. However, these symptoms are also associated with many other diseases and medical conditions.
A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.
For patients with human papilloma virus associated oropharynx cancer, assessing the presence of cancer cells beyond the lymph nodes is critical in determining proper treatment.
Radiotherapy does not improve survival rates in older patients with early breast cancer, new research suggests.
A new imaging approach using ultrafast MRI shows potential in predicting upgrade of ductal carcinoma in situ (DCIS) to invasive breast cancer at surgery.
A novel imaging agent can reduce the number of false-positive PET/CT findings among cancer patients recently vaccinated for Covid-19. This may mitigate the issue of tracer uptake in lymph nodes associaed with the vaccine.
In men recently diagnosed with intermediate or high-grade prostate cancer, PSMA PET/MRI can successfully determine whether their cancer is likely to return within two years of a prostatectomy.
AI-based models for multimodality hybrid imaging have the potential to be a potent clinical tool but are currently held back by a lack of transparency and maturity, says Dr Irène Buvat, from the Laboratory of translational Imaging in Oncology, Institute Curie in Paris, France.
In surgery, artificial intelligence (AI) is applied mostly in imaging, navigation, and robotic intervention. However, AI can also play a major role in preoperative planning. Objective decisions-making, optimal utilisation of operating theatres and less overtime are additional advantages that are achieved with the use of AI in surgery.
The diminished power of the immune system in older adults is usually blamed on the aging process. But a new study shows that decades of particulate air pollution also take a toll.
A new randomized study confirms that men with high-risk prostate cancer can be treated with a moderately shortened course (5 vs. 8 weeks) of radiation therapy.
A simple 'liquid biopsy' blood test could help guide the treatment of children with the cancer rhabdomyosarcoma, a new study reports.
UK researchers developed and validated a deep learning algorithm that can identify and outline a non-small cell lung cancer (NSCLC) tumor on a CT scan within seconds.
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
Multiparametric ultrasound (MPUS) has proven its value in the abdomen – now, the technique is increasingly moving towards peripheral areas such as breast and testis imaging, experts showed in a dedicated session at ECR 2022.
Advances in image post-processing and contrast-enhanced techniques have widened the scope of possibilities for MRI and ultrasound vascular imaging, experts showed in a dedicated course at the ECR Overture.
Microfluidic chip inflates and deflates balloons in a sleeve to promote fluid flow in the lymphatic system.
Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases. In this Medica-tradefair.com interview, Prof. Maciej Pech talks about testing cavitation events generated during histotripsy, explains the process, and reveals its advantages.
After infection with SARS-CoV-2, where does the immune system store the memory to provide long-term protection against reinfection? Though numerous studies have examined blood to track immune responses to SARS-CoV-2, a new study of Covid survivors shows that the memory of the infection is primarily stored in T and B cells within the lung and the lymph nodes surrounding the lung.
Pancreatic cancer is one of the deadliest cancers in the world, and one of the most difficult to treat. In 2020, an estimated 495,000 individuals worldwide were diagnosed with pancreatic cancer and an estimated 466,000 died, according to statistics from the World Health Organization’s International Agency for Research on Cancer. Most patients with advanced disease die within a year of…
Whole-body magnetic resonance imaging (WB-MRI) can detect prostate cancer and inform about treatment response and disease progression earlier and better than other imaging modalities. A Belgian expert will delve into the latest and future developments of the technique for prostate cancer and distant metastases imaging in a dedicated session at ECR. WB‐MRI and nuclear medicine -…
An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before. This new protocol provides detailed instructions on how to capture hi-res movies of cell movement, division and cooperation, in hard-to-reach regions of breast tissue. The technology – called multiphoton microscopy – uses infrared lasers to illuminate…
For many women, swollen lymph nodes are a red flag pointing to breast cancer – but may also be a normal immune reaction to a Covid-19 vaccination. In this Q&A, breast imaging experts address the most important facts on the topic.
Hybrid PET/CT imaging can fully play to its strengths and steer treatment towards more effective procedures for diagnosing prostate cancer. The examination of the specific antigen PSMA with hybrid PET imaging enables treatment monitoring with significantly higher diagnostic accuracy than conventional imaging and therefore, Professor Clemens Cyran believes, will soon become the standard diagnostic…
Olympus Corporation announced that it has entered into an agreement to acquire Quest Photonic Devices B.V. for up to EUR50 million including milestone payments to strengthen its surgical endoscopy capabilities. Quest offers advanced fluorescence imaging systems (FIS) for the medical field, enabling more surgical endoscopy capabilities, compared to conventional imaging technologies.
Scientists report on their detailed look at B cells' presence inside tumors. B cells represent the other major arm of the adaptive immune system, besides T cells, and could offer opportunities for new treatments against some kinds of cancers.
Breast cancers that are detected in the interval between national screening programme mammograms have a worse prognosis than those detected at the time of a screening, even if they have the same biology, according to research presented at the 12th European Breast Cancer Conference. Analysis of results from over eight years’ follow-up of the international MINDACT randomised phase III clinical…
Spatial analytics offers greater clarity in the assessment of tumours beyond routine microscopic analysis. High-capacity digital image analysis enables new methods of spatial statistics to extract features not immediately distinguishable by visual inspection. These subvisual features reflect complex properties, such as intratumour heterogeneity and have the additional benefit that they can target…
A group of researchers led by Osaka University established a new pathological grading system to evaluate the therapeutic effect of neoadjuvant chemotherapy (NAC) for metastatic lymph nodes (LNs) removed in esophageal cancer (EC) surgery, demonstrating that the system predicts recurrence and prognosis in EC patients better than conventional systems. Their research results were published in Annals…
Better outcomes, more favourable prognoses – oncologists and their lung cancer patients didn’t dare to dream about it. Finally, there might be hope. The so-called checkpoint inhibitors (immunotherapy drug) have been used successfully, albeit not for every patient. They are a double-edged sword, with risks as well as opportunities, as explained by Professor Cornelia Schäfer-Prokop.
Former ESR President Katrine Riklund will explore the clinical applications of hybrid imaging in a virtual session for the European Congress of Radiology 2020. She will discuss a number of common indications of hybrid imaging in areas of oncological diagnosis, the indications and limitations of hybrid imaging in common diseases, and the added value of hybrid imaging. “The major benefit of…
What makes tumor cells turn murderous? The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is investigating the mechanisms of metastasis formation – and searching for approaches for new treatments in the fight against cancer. Among other things, the research team at Fraunhofer ITEM has developed a method that enables them to analyze entire lymph nodes.
Biomedical researchers in Munich have isolated immune cells from human tonsils obtained following routine surgery, and used them to analyze aspects of the immune response and test the effects of anti-inflammatory agents at the cellular level. Human tissues that have been surgically removed from patients are normally treated as waste, especially when they are derived from a ‘dispensable’ organ…
Supermicrosurgery – operations on vessels ranging from 0.3 to 0.8 millimeters – is limited by the dexterity of the surgeon’s hands. To bypass this limitation, robots can assist in the surgical process. One such robot is MUSA – the world’s first robotic platform for supermicrosurgery, which was co-developed by researchers from Eindhoven University of Technology (TU/e) and the TU/e…
Whole-body magnetic resonance imaging (WB-MRI) is championed as offering significant benefits, such as improving disease evaluation for prostate cancer patients. During an intense session in genito-urinary cancer at ECR 2019, three key speakers focused on the advantages over conventional imaging modalities as well as discussing new PET (Positron Emission Tomography) tracers.
Pathology is embracing digitisation just as radiology did over 20 years ago and both specialties are looking at new ways to integrate each other in their workflows. AI could fuel this sparkling alliance, giving it further means to improve cancer treatment.
Cancer of unknown primary (CUP) can send radiologists on a frustrating scavenger hunt: metastases were detected but the primary cancer is nowhere to be seen. Professor Alwin Krämer, Head of the Clinical Cooperation Unit Molecular Haematology/Oncology at University Hospital Heidelberg and the German Cancer Research Center, explains strategies for dealing with CUP.
Prostate-specific membrane antigen imaging should be the positron emission tomography imaging agent of choice for men who have a prostate cancer recurrence after radical prostatectomy, which needs to be detected and located. For these men, it should become the standard of care, new research shows.
New results of a 65-year follow-up study of nearly 7,000 Norwegian patients with Multiple Sclerosis (MS) suggest that patients may have a greater overall risk of developing cancer than the general population, with an especially high risk of cancer in respiratory organs, urinary organs and the central nervous system. Presented at the 5th European Academy of Neurology (EAN) Congress in Oslo,…
A new deep learning algorithm, which demonstrates the potential of artificial Intelligence (AI) to support pathologists, has been developed for PD-L1 scoring in tumour cells and immune cells in urothelial carcinoma samples. Speaking at the Digital Pathology and Artificial Intelligence Congress in London last December, Dr Michel Vandenberghe, from AstraZeneca, outlined how PD-L1 expression level…
Beckman Coulter is launching the ClearLLab 10C System for the clinical flow cytometry lab. The new system is the first 10-color IVD panel of immunophenotyping reagents cleared by the Food and Drug Administration (FDA) for both lymphoid and myeloid lineages. The four dry pre-mixed antibody tubes use the company’s DURA Innovations technology, eliminating the need to pipette antibodies, improving…
Women with early, low risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment, according to results from a trial that has followed 869 women for ten years. New findings from the 8 A trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG), presented at the ESTRO 38 conference,…
Radiologist Alexis Kelekis, Associate Professor of Interventional and Musculoskeletal Radiology at Attikon University Hospital, Athens, speaks about his work and developments in merging scans and techniques to gain greater accuracy in diagnosis and planning. The benefits of fusion imaging are widely acknowledged. Favoured in clinical practice by radiologist Alexis Kelekis, he explained: ‘The…
The first report from a phase II, multi-center clinical trial indicates that a newer, more aggressive form of radiation therapy — stereotactic radiation — can extend long-term survival for some patients with stage-IV cancers while maintaining their quality of life. The study is published in the January issue of International Journal of Radiation Oncology • Biology • Physics (Red Journal),…
When Olivia Nelson was 3 years old, her parents noticed that she had a fever that wouldn’t get better. They brought her to a nearby hospital, where she spent about two weeks being screened for diseases. As doctors tried to find a diagnosis, a lymph node on Olivia’s neck became swollen. Alarmed and wanting an answer, the Nelsons asked to transfer to Seattle Children’s. “It was very…
Leeds Teaching Hospitals NHS Trust and the University of Leeds have announced a critical milestone in going digital, by scanning every glass slide they produce. The milestone represents a major step towards achieving faster and accurate diagnosis for cancer patients in the future. The Pathology Department, located in St. James’ Hospital in Leeds, is one of the largest in the UK processing over…
Built as the first commercially available scanner to deliver truly digital PET, the Vereos PET/CT, from Philips, offers revolutionary Digital Photon Counting technology. The science behind this scanner evolution is ‘quite complicated’, agrees Piotr Maniawski, Director of Clinical Science Nuclear Medicine at Philips Healthcare, yet the improved performance is significant, particularly when…
Machine learning is adding a new dimension to pathology and already outperforming experts during some tasks, according to several speakers at the 14th European Congress on Digital Pathology (ECDP) who revealed up-to-date developments. However, whilst AI is set to herald a new future for digital pathology, Johan Lundin, associated professor for biomedical informatics and research director at the…
Jan Walker, a retired administrative assistant to the superintendent of Boaz City Schools, was getting ready for her regular doctor visit and noticed a lump on her neck. Her primary care physician examined it and determined it was a simple swollen lymph node. Two months later, she began to lose feeling on the right side of her throat and noticed the lump had increased in size. After seeing other…
Extensive surgery involving mastectomy and removal of several lymph nodes can be safely avoided for more women with some types of breast cancer, if they receive targeted drugs before surgery, according to research presented at the 11th European Breast Cancer Conference. The study focused on women with HER2 positive breast cancer, an aggressive form of the disease, who were given a targeted drug…
As early detection and treatment of breast cancer improves, more and more women are surviving the disease. However, they still face challenges, which include determining the moment when it might be reasonable to state they are “cured” of the disease, and obtaining life insurance. “In the Netherlands, most applications for life insurance are accepted, but not for cancer survivors. A lot of…
With immunotherapy, bigger lesions may be spotted on CT, but it doesn’t necessarily mean that the disease is progressing. As treatment works, it can cause what has become known as pseudo disease progression; and this is just one of the many revolutions immunotherapy is triggering in oncology imaging, Professor Clarisse Dromain (Lausanne/CH) explained as she opened the session dedicated to this…
Machine learning is playing an increasing role in computer-aided diagnosis, and Big Data is beginning to penetrate oncological imaging. However, some time may pass before it truly impacts on clinical practice, according to leading UK-based German researcher Professor Julia Schnabel, who spoke during the last ESMRMB annual meeting. Machine learning techniques are starting to reach levels of human…
In April 2016 CEUS received the USA’s FDA approval. This year‘s RSNA Samsung Symposium ‘Contrast-Enhanced Ultrasound (CEUS): Innovations and a Problem-Solving Tool in Clinical Practice’ provided an opportunity to take stock. For European Hospital, Professor André Clevert, Director of the Interdisciplinary Centre for Ultrasound at University Hospital Munich, Germany, describes the current…
A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients. The study, published in the Journal of Experimental Medicine, reveals that ibrutinib has a diminished capacity to delocalize and kill tumor cells expressing an adhesive protein called CD49d, but combining ibrutinib…
Lars Schimmöller MD, associate professor of radiology at Düsseldorf University Hospital, tackled current diagnosis of prostate cancer (PCa) and addressed tumour detection, staging, active surveillance and recurrence during the Medica Academy session on Imaging Update. He also highlighted how MRI helps improve biopsies and avoid unnecessary surgery in PCa.
Scientists are using their increasing knowledge of the complex interaction between cancer and the immune system to engineer increasingly potent anti-cancer vaccines. Now researchers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a synergistic nanovaccine packing DNA and RNA sequences that modulate the immune response, along with anti-tumor antigens, into…
Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team of investigators published in the New England Journal of Medicine. Standard treatment for estrogen receptor-positive, or ER-positive, breast cancer includes five years of the endocrine-based…
Surgeons at Penn Medicine are using a fluorescent dye that makes cancerous cells glow in hopes of identifying suspicious lymph nodes during head and neck cancer procedures. Because the tumors glow, surgeons get real-time guidance to help them take out as much cancer as possible and leave non-diseased tissue alone.
Pentax Europe, a healthcare industry leader in endoscopic imaging, and Hitachi Medical Systems Europe, a leading company in medical imaging, recently announced renewed joint collaborative efforts to enable further innovations in the development of endoscopic ultrasound (EUS). In this latest joint development, the two companies are launching a new ultrasound video bronchoscope for endobronchial…
In the nineties Deep Blue, the famous chess computer, defeated Kasparow. Only a year ago Google’s Deepmind managed to master the ancient Chinese Go, known for its utmost complexity.
Digital pathology has been the next big thing for about a decade. Yet, today only a few pathology laboratories are fully equipped to digitise their workflow, mainly for legal or financial reasons.
Johns Hopkins Kimmel Cancer Center scientists report they have discovered a biochemical process that gives prostate cancer cells the almost unnatural ability to change their shape, squeeze into other organs and take root in other parts of the body.
Pancreatic cancer is one of the most deadly types of malignancies, with a 5-year survival rate after late diagnosis of only about 5%. The majority of patients—about 80%—receive their diagnosis too late for surgery. The disease spreads quickly and resists chemotherapy. In short, there is an urgent need for diagnostic tools to identify this cancer in its earliest stages.
A new test may help to identify breast cancer patients with the lowest risk of death, therefore helping them to avoid unnecessarily aggressive treatment.
Visiopharm A/S announces the first result of their multifaceted strategy to apply Deep Learning technologies to its leading image analysis solution for cancer research and diagnostics. Visiopharm considers Deep Learning an important technological breakthrough for tissue pathology that offers the potential to make a real difference in the assessment of tissue structures, which is probably one of…
Patients with locally advanced rectal cancer have been treated with intra-operative radiotherapy (IORT) for over twenty years. Partly due to this type of radiation, survival rates in a group of patients considered to have inoperable cancer changed dramatically from five to 70 percent.
Bladder cancer (BC) is the most common malignancy involving the urinary system and the ninth most common malignancy worldwide.
n type 1 diabetes, the body attacks its own insulin-producing cells. Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have now reported in the journal ‘PNAS’ about a mechanism used by the immune system to prepare for this attack. They were able to inhibit this process through targeted…
One of the earliest widespread applications of precision medicine in cancer care is helping patients and physicians decide whether chemotherapy is needed, a new study finds.
Melanomas account among the eight most frequent deadly cancers in Europe and Northern America. Two major clinical criteria separate melanomas from most other cancers: the risk to die from a melanoma is a question of being less or more than 1 mm – and not a question of cm. About 95% of patients with melanomas ≤0.5 mm in thickness are clinically cured by early detection and appropriate melanoma…
Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed. A research team from Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS) recently developed…
Mobile technology could prove an important catalyst in helping take digital pathology onto a new level in delivering clinical diagnostics.
Eckert & Ziegler AG, a specialist for isotope-based applications in medicine, science and industry, is expanding its cooperation program with promising drug developers in the field of nuclear medicine and will support Curasight, a spin-off based on research by the group of Professor Andreas Kjaer at the National University Hospital (Rigshospitalet) and University of Copenhagen, in obtaining…
Building on an innovative ultrasound technology that continues to yield break-through capabilities, SuperSonic Imagine is introducing AngioPLUS, a third diagnostic functionality for its Aixplorer platform that promises to be instrumental in the diagnosis of cancerous tissues as well as musculoskeletal pathologies.
The view across the Atlantic – it fills Professor Fabian Kiessling, Chair of Experimental Molecular Imaging at the RWTH Aachen (Rhine-Westphalia Institute of Technology Aachen), with optimism. The USA offers more opportunities for molecular imaging. Only recently, new tracers for Alzheimer’s were accepted as reimbursable in some centres, whilst the development of new diagnostics in Europe…
Results from a randomised controlled trial to compare the use of permanent radioactive implants (brachytherapy) with dose-escalated external beam radiotherapy in patients with prostate cancer show that the men who received brachytherapy were twice as likely to be cancer-free five years later. These results presented Professor James Morris, from the Department of Radiation Oncology, Vancouver…
PET scanners are not the only way to image radiotracers. Recent work developed around a phenomenon called Cerenkov luminescence aims to bring a new modality out of preclinical development and into clinical practice.
For medical ultrasound it’s quick, easy and portable – and so popular with Professor Christoph Dietrich, chief of Medical Department 2 at Caritas Hospital, Bad Mergentheim, one of the first physicians worldwide to test the M9 in clinical routine. ‘The compact Mindray colour Doppler system is about the same size as a notebook computer. The imaging suite comes to the patient,’ the…
‘An intelligent imaging tool, Superb Microvascular Imaging (SMI) moves beyond conventional colour Doppler technology by applying a unique algorithm allowing visualisation of small vessels with low velocity, while maintaining high resolution, minimal motion artefacts and high frame rates,’ Toshiba proudly reports.
The Aplio, Toshiba’s flagship ultrasound scanner, has been extensively advanced and essentially turned into a new system. The highly innovative Japanese company in imaging diagnostics has refined the successful Aplio series of scanners and introduced it internally in Frankfurt at the beginning of October.
In studies on prostate cancer, scientists from the German Cancer Research Center (DKFZ) simultaneously investigated the genetic and epigenetic development of the tumors.
The multiple benefits of PET/CT are undisputed – one being the fact that radiopharmaceuticals, which are used at pico and nano levels – are not toxic.
It looks like a drug, it is injected in patients like a drug, but its acts like a medical device. Welcome to the new world of nanomedicine.
An innovative technology is enabling radiologists to provide more accurate diagnoses.
Ultrasound may be used during breast conservation surgery, to locate tumour lesions or to place localising wires; it can also guide a lumpectomy and perform a specimen exam to ensure a lesion has been excised and to evaluate surgical margins
Hedvig Hricak, Chair of the Radiology Department at the Memorial Sloan-Kettering Cancer Center, New York, USA, describes emerging applications and potential trends in gynaecological cancer treatment described at the 15th International Symposium Crossing Barriers
Staging of cervical cancer is clinically based on a system developed by the International Federation of Gynaecology and Obstetrics (FIGO). The staging is clinical because the majority of cases occur in developing countries where access to MRI is limited, explains gynaecological radiologist Dr Evis Sala.
At RSNA 2012, Siemens is launching its new MRI addressing academic research centres and university hospitals. According to Bernd Ohnesorge, the Magnetom Prisma 3.0 T enforces the company’s major commitment to advancing research, bearing testimony to Siemens’ innovation leadership in the field. In Chicago, the CEO of the Siemens MRI business unit presented the 3 T system for which the company…
Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.
Although most nuclear medical examinations using SPECT (single photon emission computed tomography) take place beyond hospitals, two to three times more SPECT exams than PET-CT exams are carried out within hospitals.
Germany’s mammography screening programme, introduced in 2005, was rolled out across the country in 2009 for women between the ages of 50 and 69 years. The mammo screening coordination office, which heads up and monitors the country’s 94 screening units, has published for the first time an evaluation report with follow-up examinations after a twoyear period.
Virtual FDG-PET/CT bronchoscopy has been found to be a technically feasible tool for the detection of lymph node metastases in non-small cell lung cancer patients with good diagnostic accuracy, according to researchers at the Department of Diagnostic and Interventional Radiology, University Hospital Dusseldorf and Essen.
A series of papers presented at the European Congress of Radiology on Friday have highlighted how hybrid imaging is helping radiologists achieve better results in the diagnosis of patients’ conditions. In a session focussing on molecular imaging and entitled “Hybrid imaging: PET-CT and MR-PET”, findings from ten different research papers were detailed by radiologists from Italy,…
Early this year the radiology and nuclear medicine practice of Doctors Andreas Blynow, Frank Muller, Jorg Kowalski in Ludwigshafen, Germany, began to offer breast examinations using Europe’s first Positron Emission Mammography (PEM) scanner. With 15 years experience with Positron Emission Tomography (PET), Dr Muller introduced the new PEM scanner to the partners’ practice to detect and assess…
Critical ultrasound, as a tool for immediate therapeutic decisions, and emergency POC ultrasound – an extension of the clinical examination at the bedside or on the accident scene – have shown clear benefits along with lung ultrasound.
2011 brought a second year for European and US scientists to meet up at the Annual Scientific Symposium on Ultra High Field Magnetic Resonance, held at the Max Delbrück Centre for Molecular Medicine Berlin-Buch (MDC), Germany, to present and discuss their recent findings. Along with technical improvements, the main issues of the one-day gathering were cardiac, cerebral and molecular MR imaging.…
Dr Helmut Prosch, at the University Clinic for Radio-Diagnostics, Vienna, Austria, is examining the role of imaging in lung cancer diagnosis and staging. The key message of his presentation in the session EUS and EBUS vs. CT, MR and PET-CT in the staging of lung cancer is that the modalities do not compete with one another – as the title suggests – but are perfectly complimentary in the…
Sahlgrenska University Hospital provides emergency and basic care for the 700,000 inhabitants of the Gothenburg region. It also provides highly specialised care for the 1.7 million inhabitants in Sweden’s west because, in this country, endoscopic ultrasound examinations are only provided in university hospitals. Thus Sahlgrenska’s physicians receive referrals of difficult diagnostic cases…
Breast cancer is the most common form of cancer in women. Evaluation of the axillary lymph nodes is essential to insure complete cancer removal. Fluorescence imaging instead of radioisotopes is an innovative method for sentinel lymph node detection.
Thinking of the future of imaging, inevitably PET-MRI springs to mind. The fascination of this novel hybrid technology is great, seeing how it combines the best from three imaging areas: anatomy, function and metabolism. The further development of functional procedures in oncology is raising particularly high expectations. However, how extensive the use of this potentiated image information will…
Until now, interventional and endoscopic therapies have held little importance in common cancer treatment. However, given the trend towards personalised medicine and targeted cancer therapy, increasing attention is being paid to reasonable complements to traditional cancer surgery.
Malignant diseases rank second in mortality rates in Germany. These patients thus receive a major proportion of ambulant and hospital care, with apparent socioeconomic consequences. To optimise treatment planning, for all solid tumour entities it is mandatory to delineate or stage the primary extent of tumour invasion and spread prior to therapy as precisely as possible.
During his Honorary Lecture at the 8th Düsseldorf Breast Cancer Conference in Germany world renowned surgeon and oncologist Prof. Veronesi reflected about the prevention and treatment of breast cancer.
Italian surgeon and oncologist Prof. Dr. Umberto Veronesi, Founder and Scientific Director of the European Institute of Oncology in Milan and former National Health Minister (2000 – 2001), is considered to be one of the biggest authorities on breast cancer research of our time. Many breakthrough changings in cancer medicine sustainably go back on his researches, which once earned him also a…
Biopsy developed into an invaluable diagnostic tool in many organ systems. Advanced imaging technologies have helped shift biopsy techniques away from more invasive approaches toward imaging-guided percutaneous or through the skin techniques, according to a new study appearing online and in the September print edition of the journal Radiology.
Siemens Healthcare was presenting its latest solutions for the early detection and treatment of breast cancer at the German Radiology Congress in Berlin. These Breast Care Solutions include a variety of imaging procedures, such as ultrasound, mammography, and magnetic resonance imaging (MRI), supplemented by IT and laboratory diagnostic solutions. Siemens places special focus on the third…
A special feature of this year’s scientific program at ECR 2010 was a joint session organized by the European Association for Nuclear Medicine with the European Society of Radiology. Two speakers representing the EANM took the podium to review developments in nuclear medicine and to challenge colleagues on specific applications.
Definiens announced the launch of Definiens LymphExpert Version 2.0 at ECR 2010. The Software application assists radiology professionals in the identification, analysis and evaluation of lymph nodes in CT images over time.
At this year’s ECR, new developments will be outlined during the Contrast agents: Experimental and Clinical session. Mark Nicholls spoke with the session moderator Professor Peter Aspelin, Professor in Diagnostic Radiology at the Karolinska Institute, Stockholm, about their potential.
Acoustic Radiation Force Impulse Imaging (ARFI) is a new tissue strain imaging technology that utilizes sound waves to interrogate the mechanical stiffness properties of tissue. Virtual Touch™ Tissue Imaging and Virtual Touch™ Tissue Quantification are available on the Siemens ACUSON S2000™ ultrasound system.
The so-called lymphoma, which are cancers of the immune system, originate in white blood cells. Pathological B cells, for instance, are responsible for the "diffuse large B cell lymphoma", which progress very aggressively if left untreated. Now a new approach for future therapy of this cancer has been found by an international research consortium. They present their research in the scientific…
In recent years Hitachi Medical, the pioneer in developing ultrasound elastography to diagnose tissue stiffness, has seen competing systems launched that claim to have the same capability. ‘We are approaching a point where elastography will be considered a standard feature, call it the E-mode, for ultrasound,’ Heinz Schreiber, head of Ultrasound for Hitachi Medical Systems Europe told…
For many indications, because PET-CT produces a very high accuracy for many tumours, this modality is the gold standard, Prof. Reiser confirmed. It also enables good observation of the course of the disease. After an injection of radioactive tracers we can visualise increased metabolic activity in great detail and with high sensitivity. This is an increasingly important issue not only in primary…
Emphasising the crucial partnership of radiologists and urologists in the treatment of prostate cancer, Professor Arnulf Stenzl, Medical Director of Urology at the Tübingen University Hospital, explained that, throughout the phases of prostate cancer diagnosis and therapy - from primary diagnosis onward - imaging is indispensable.
During a gathering of clinicians, scientists and economists at this year's Medical Technology Congress (Treffpunkt für Medizintechnik) held in Berlin's Charité Hospital, all 17 lectures focused on cancer treatments. Bettina Döbereiner reports
Researchers around the globe are studying whether a genomic test, developed with micro-array technology, is superior to traditional methods in assessing aggressive breast cancer, and therefore could spare a considerable percentage of women from the onslaught of chemotherapy The Breast International Group (BIG) in Brussels, Belgium, manages TRANSBIG, an international network created to avoid…
This newly developed digital ultrasound system is fully software orientated and features the latest broadband beamforming technology and ultra high-speed processing capability together with single crystal transducer technology. Combined with advanced ergonomic design, the system blends exceptional levels of user friendliness with superior image quality to guarantee maximum diagnostic confidence…
Studies show promise for fast, 5-day therapy for early-stage breast cancer patients
Definiens, the number one Enterprise Image Intelligence company, launched its first computer-aided detection (CAD) application, Definiens LymphExpert at the annual European Congress of Radiology (ECR) in Vienna, Austria. Now commercially available for European radiologists, the application assists in tracking lymph nodes of interest, facilitating earlier detection of the metastatic spread of…
Dr Giorgio Rizzatto, who heads the Department of Diagnostic Imaging at ASS 2 Isontina (including the Gorizia and Monfalcone hospitals) in NE Italy, works with nine radiologists, who examine and report on 80,000 clinical and screening breast examinations annually.
Early detection currently remains the most promising way to optimise the diagnosis and treatment of breast cancer, lower the mortality rate resulting from this disease, and improve patients' quality of life.
Although its standard description is simple: Photo detection at low light levels where single photon absorption events are counted, according to an internationally renowned medical imaging scientist, in terms of X-ray imaging, counting photons may really be the way to see the light.
Lymph nodes play a critical role in the assessment of the spread of cancer, but identifying lymph nodes in surrounding tissue is a difficult task for most image analysis technology. German medical imaging company Definiens now introduced at RSNA 2008 its first computer-aided detection (CAD) application, Lymph Expert, that allows radiologists to identify and analyse lymph nodes volumetrically and…
Olwen Glynn Owen reports on MammaPrint, a test that pinpoints the risk of breast cancer recurrence from the primary tumour's genetic make-up. Women with breast cancer tumours under
Sonoelastography, a procedure that measures the elasticity of tissue and differentiates between healthy and hardened pathological tissue, will make cancer diagnosis safer in the future. For example, it has been shown to improve the accuracy of prostate cancer diagnosis by 20%.
At this year's RSNA meeting, Definiens, the number one Enterprise Image Intelligence company, will introduce a new image analysis application that will allow radiologists to analyse lymph nodes volumetrically and compare them over time.
German scientist Harald zur Hausen showed that oncogenic human papilloma virus (HPV) cause cervical cancer, the second most common cancer among women. Françoise Barré-Sinoussi and Luc Montagnier from France discovered HIV.
With the help of an engineered common cold virus spreadings of prostate cancer in the pelvic lymph nodes can be visualised with a PET scanner. It is now possible to treat the cancer in an early stage. But the developers of the virus from UCLA's Jonsson Comprehensive Cancer Center see a chance to even use it as a treatment option.
Prostate cancer is the most frequent cancer in men with about 49,000 newly diagnosed cancers in Germany and 6,000 in the Netherlands, annually.
Can they replace PET? By Marco Essig MD, Professor of Radiology at the German Cancer Research Centre, outlines relevant presentations at the ECR.
By Rudolf Schwarz and Andreas Krüll, of the Section of Radiation Oncology Department, Ambulanzzentrum GmbH of the University Medical Center Hamburg-Eppendorf
PET/CT imaging exhibits significantly higher sensitivity, specificity and accuracy than conventional imaging when it comes to detecting malignant tumours in children, according to research published in the Journal of Nuclear Medicine (12/07).
For individualised radiotherapy, high-precision delineation and characterisation of the tumour is critical. If highest radiation doses are delivered in a targeted fashion, the chance of tumour cell kill increases and tumour control probability is enhanced.
Growing interest in sentinel lymph node (SLN) detection has led to its use in many clinical centres. The most successful protocols for localisation of SLNs are those that include preliminary lymphoscintigraphy performed with a conventional gamma-camera. In the absence of a nuclear medicine department, SLN protocols using only an intra-operative counting probe are generally less efficient. To…
UK - Optical imaging company Michelson Diagnostics Ltd (MDL) has announced successful initial results from clinical testing of its novel optical coherence tomography (OCT) imaging technology. The tests, performed on cancerous and precancerous human oesophagus and lymph node tissue, were designed to establish the potential value of MDL's optical imaging technology used during cancer surgery.
The Vestfold County Study, performed by Norwegian researchers, is the first large scale study comparing the results of a particular full-field digital mammography system (FFDM) with that of conventional mammography. Einar Vigeland, Department of Radiology, Vestfold Hospital, Tønsberg, Norway, and his colleagues collected data over a period of two years.
Researchers at A Seattle Children's Hospital Research Institute and Fred Hutchinson Cancer Research Center developed a tumor paint that will help surgeons see where a tumor begins and ends more precisely by illuminating the cancerous cells.
The well-known Whipple procedure, or pancreaticduodenectomy, recently underwent a transformation due to the skills of Nerijus Kaselis MD, Head of Abdominal and Endoscopic Surgery at Klaipeda District Hospital.
Like any other congress, the 88th German Radiology Congress will present the latest research, workshops and refresher courses.
`ELIOT means that single-fraction radiation of 21 Gy is delivered directly to the tumour bed during a surgical intervention, to a depth of about 3 cm,´ Professor Prott explained.
Gadofosveset trisodium (trade name: Vasovist) is the first approved blood pool contrast agent worldwide for the diagnosis of vascular disease, Bayer Schering Pharma AG reports.
A new testing approach has effectively identified patients at the highest risk of cancer relapse after bladder cancer surgery, according to a study published in the February issue of The Lancet Oncology http://oncology.thelancet.com. Vol 8 Feb 2007 91.
Targeted medication and gentle surgical procedures are the pillars of modern breast cancer therapy, according to participants at this years German Congress of Senology.
By Stefan G Ruehm MD PhD, Associate Professor of Radiology, at the David Geffen School of Medicine, UCLA, California
Dr Hanns-Joachim Weinmann, Diagnostics and Radiopharmaceuticals, Magnetic Resonance Imaging & X-Ray Research, Schering AG, examines what is feasible and what still lies only at a tantalising distance.
When it was suggested, during our interview with Dr Torsten Kuwert, Director and Professor of Clinical Nuclear Medicine, Clinic of Nuclear Medicine, at Friedrich-Alexander University Hospital, Erlangen, that SPECT-CT is the little sister of PET-CT, and that he might have preferred to install the ‘big brother’, Dr Kuwert pointed out the greater cost of PET, explaining: ‘The isotopes are more…
The Masaryk Memorial Cancer Institute (Masarykúv onkologick´y ústav - MOÚ) in is unique in the Czech Republic, for it covers all aspects of cancer care, provides medical training plus public health education, and participates in research. Around 180,000 outpatients and about 7,000 in-patients are treated annually. By Pavel Andres MD, Deputy Director of Medical Preventive Care at the Masaryk…
Researchers open up new opportunities for cellular and molecular MR imaging.
Five years of therapy with the drug tamoxifen has become the norm for postmenopausal women with hormone-sensitive breast cancer. However, this has several adverse side effects, and studies have continued to compare the effects of other drug therapies with tamoxifen.
Mammography plays a critical part in diagnosing breast cancer. Although this does not prevent the disease, diagnosing breast cancer as early as possible can save lives.