Search for: "resistance" - 250 articles found

News • Oncology

Nanozymes take on brain tumours from the inside

Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.

News • Focal cortical dysplasia

Lab-grown mini-brains shed light on childhood epilepsy

Why does the same genetic mutation cause FCDII in some patients but not in others? Researchers developed organoids to model a brain malformation responsible for drug-resistant epilepsy in children.

News • Immunology

How obesity impairs vaccine response

Being overweight can reduce vaccine effectiveness, new research finds. The findings explore differences in immune response, and may lead to more effective vaccines for patients with obesity.

News • Prediction of treatment response

Colon and rectal cancer: new biomarker shows which patients benefit from immunotherapy

A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.

News • Potential osteoarthritis treatment

Researchers investigate menstrual blood for cartilage repair

New research reveals that extracellular vesicles derived from menstrual blood stromal cells can improve cartilage repair, suggesting an innovative cell-free therapy for osteoarthritis.

News • Genetic CAD risk scores

Researchers link diabetes subgroups to coronary heart disease risk

Researchers have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease.

News • Review on treatment outcomes

Exploring the impact of chronic stress on cancer

A new review shows that chronic stress may actively drive cancer progression. Therefore, psycho-oncology should be part of standard cancer care, the researchers argue.

News • PARP inhibitors distribution

“Hidden drug storehouses” could explain treatment resistance in cancer

Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.

News • Neuro-oncology

Simple blood test could detect glioblastoma in the future

Glioblastoma is notorious for late diagnosis, rapid progression, resistance to treatment and its biological complexity. A new experimental method could help detect this deadly type of brain cancer.

News • Triple-negative breast cancer

TNBC can become treatment-resistant in more ways than one

About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.

Article • Equity, access, and the future of radiotherapy

Radiation oncology: the beam widens

Radiation oncology is a field in remarkable transformation: a deepening global shortage of trained practitioners, persistent inequities in access to treatment – and, on the other side of the ledger, a new generation of technologies, from AI-driven adaptive planning to photon-counting CT, that are expanding what the field can do in ways previously unimaginable. At this year’s World Health Expo…

News • Biofilm-based resistance mechanism

Bacteria build “bunkers” to withstand antibiotic treatment

“The bacteria effectively hide in a bunker”: New research reveals a surprising mechanism used by Acinetobacter baumannii and Pseudomonas aeruginosa to protect themselves from antibiotics.

News • (B)eating cancer

Bacteria to consume tumours from the inside out

A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.

Consumables for Pathology / Histology

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News • Treatment approach

How to improve cancer cure rates? “Kick it while it’s down”

Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first.

News • AI detects unseen connection

Insulin resistance identified as risk factor for cancer

Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.

News • Assessing infection risk

Predicting neonatal sepsis with vaginal microbial swabs

A new study shows that analyzing bacteria from vaginal swab samples taken at delivery could help predict the risk of neonatal sepsis.

News • Research on metastasis mechanism

How ovarian cancer hijacks abdominal cells as an invasion force

Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.

News • Two tracers, one target

Dual PET approach for personalized head and neck cancer treatment

Beyond "one-size-fits-all": A new strategy that combines two types of PET scans can guide personalized radiotherapy for head and neck cancers, according to new research.

News • Soft tissue ablation

Adapting eye-laser technology to remove cancer

Scientists have shown that a type of laser similar to the one currently used in routine eye surgery could one day help surgeons remove unwanted tissues, such as tumours, with unprecedented accuracy.

News • Exploring metastatic potential

AI predicts risk of cancer metastases

Why do some tumours spread while others remain localised? Using colon cancer cells, scientists pinpointed the criteria that influence metastasis risk, and identified a way to assess its probability.

News • Plasmid-specific ecological adaptation

How antimicrobial resistance spreads from gut bacteria to hospital superbugs

Researchers have uncovered how a high-risk class of genetic vectors can efficiently spread antibiotic resistance within the gut, enabling even highly virulent bacteria to acquire drug resistance.

News • Disease tolerance and infection pathogenesis

Different age, same infection treatment? Not a good idea, study finds

Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.

News • Focus on tumor STAT1 acetylation

How cancer cells learn under pressure to evade immunotherapy

Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.

News • Clinical phase entered

'Final push' for new device to prevent birth trauma

A first-time mother has about a 30% chance of complication in the second stage of labour, requiring assisted delivery or emergency C-section. A new device could help reduce birth trauma.

Article • Hospital hygiene

Breaking chains of infection to combat antimicrobial resistance

With antimicrobial resistance causing over 5 million deaths annually, rapid outbreak detection is critical. A German lab demonstrates how FTIR spectroscopy can transform hospital infection control.

News • Rapid diagnostics

New system simultaneously detects antibiotic resistence and virulence of K. pneumoniae

Now, a research team has developed a novel diagnostic approach that enables the rapid and simultaneous detection of both antibiotic resistance and high virulence in Klebsiella pneumoniae.

News • When good bacteria fight back

Klebsiella strain to protect against IBD gut infections

New research shows that a harmless strain of Klebsiella – discovered by chance in laboratory experiments – can eliminate infections and reduce gut inflammation in inflammatory bowel disease (IBD).

News • Global rise in infectious diseases

'Creeping catastrophe': New study warns of health impact of climate change

Climate change, poverty, and drug resistance are combining to create an escalating health crisis that could become a ‘creeping catastrophe’ if left unaddressed, a new international study finds.

News • Dissemination of antimicrobial resistance

Microplastics serve as hideout for AMR bacteria, study finds

Microplastics pose a human health risk in more ways than one, a new study reveals: not only do the particles harbor pathogenic bacteria, they may also help the spread of antimicrobial resistance.

News • New insights on nosocomial pathogen

Research reveals ‘hidden movement’ of Pseudomonas aeruginosa

Pseudomonas aeruginosa, a hospital-acquired bacterium that causes serious infections, can move from the lungs to the gut inside the same patient, raising the risk of sepsis, new research reveals.

News • Exploration of novel biomarkers

Depression: not just a disease of the mind

Depression is not only a disease of the mind or the brain, a new study finds: a research team has revealed deep connections to abnormalities in the body's overall immune response.

News • Bacteria-eating viruses

New phages spark hope against hospital superbug

A team of researchers comprehensively catalogued a new collection of bacteria-eating viruses called phages. These phages could be used to combat Klebsiella pneumoniae - a serious threat in hospitals.

News • New targetable driver of growth found

Thyroid gland: unexpected key to prostate cancer treatment

An international research team has discovered a promising new therapeutic approach for aggressive prostate cancer – in the thyroid gland.

News • Manganese MOF nanoparticles

New material to make MRI contrast agents greener, safer, sharper

Metal-organic frameworks (MOFs) serve as the basis for a novel type of MRI contrast agent, which the developers hope can outperform current agents while being less toxic for the patient.

News • Dual-barrier tumours

How colorectal cancer evades immunotherapy (and what to do about it)

Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.

News • Polycystic ovary syndrome

PCOS: discovery of four subgroups enables personalized treatment

Not all PCOS is the same: Researchers identified four subgroups with distinct symptoms and different responses to treatment – opening the door to precision medicine for millions of women worldwide.

Article • Affordable, sustainable – but underused

Low-field MRI: The imaging solution radiologists haven't learned to trust

At the 2025 ESMRMB Annual Meeting in Marseille, speakers made a strong case for what remains an outsider in radiology: low-field MRI. Despite its affordability, improved performance, and reduced environmental footprint, the technology continues to face scepticism – not from regulators or patients, but from radiologists themselves.

Article • Reshaping GI cancer care

Pathologists at the heart of precision oncology

Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…

News • Long-term subcutaneous EEG

Breaking new ground to advance seizure monitoring and epilepsy diagnosis

Traditional diagnostic methods for epilepsy face significant limitations. A new clinical trial explores the potential of advanced brain monitoring to improve diagnosis and management of the condition.

News • Research reveals infiltrating microbes

How bacteria in tumors drive treatment resistance in cancer

Researchers have discovered a previously unknown mechanism that explains how bacteria within a tumor can drive treatment resistance in patients with oral and colorectal cancer.

News • Nuclear imaging

Prostate cancer: High-speed whole-body SPECT tracks tumor evolution

A new type of SPECT imaging provides strong prognostic information to guide prostate cancer treatments according to tumor evolution, significantly impacting patients' overall survival.

News • New biomaterials

Building durable, infection-resistant implants with liquid metal

Integrating liquid metal nanomaterials into a ceramic scaffold could improve the durability and biocompatibility of orthopedic implants, while also combatting antimicrobial resistance.

News • Study explores clinical potential of WGS

Whole genome sequencing could help 15,000 breast cancer patients per year, study finds

Breast cancer claims around 670.000 lives each year. Now, researchers propose that whole genome sequencing (WGS) could help many patients find better treatments or match them with clinical trials.

News • Focus on adipose tissue metabolism

Endometrial cancer: visceral fat may drive aggressiveness

Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.

News • Diagnostics

Fast candida detection through sugar pattern analysis

Scientists created precise replicas of Candida sugar coats to understand immune responses, enabling fast bedside testing that could replace slow lab cultures.

Article • Opioid and alcohol-related disorders in healthcare

Managing inpatients with substance abuse disorders

The number of patients with substance abuse disorders who are admitted to hospitals as inpatients has been steadily increasing. Hospitalists attending SHM Converge 2025, the annual meeting of the Society of Hospital Medicine (SHM) in Las Vegas this spring, were given practical advice on how to treat these patients.

News • Virology

HIV genome integration mechanism decoded by German researchers

German researchers discover how HIV selects genome integration targets using RNA:DNA hybrids as guides, revealing new therapeutic approaches for controlling viral reservoirs.

News • EGFR-mutated non-small cell lung cancer

NSCLC: Surgical combination therapy may prolong disease control

In metastatic EGFR-mutated non-small cell lung cancer (NSCLC), targeting residual disease through surgery can extend the benefits of EGFR TKI therapy beyond standard monotherapy, a new study finds.

News • In situ printing of biodegradable implants

Fixing bone fractures with a glue gun? Not as crazy as it sounds

Historically, implants to repair bone fractures have been made of metal, donor bone, or 3D-printed material. Now, scientists propose an in-situ printing approach - using a modified glue gun.

Article • Hospitalists explore diagnostic and therapeutic adjustments

Dual challenge: Managing critical care of the pregnant inpatient

Hospitalists face a dual challenge when a critically ill pregnant patient is admitted to a hospital: providing safe and effective treatment for both mother and fetus. Pregnancy causes physiologic changes as well as anatomical ones, which complicates the assessment and medical management of pregnant women. At the annual meeting of the Society of Hospital Medicine (SHM) in Las Vegas, an expert…

News • Materials science meets medicine

Exploring why implants fail in the body

Even though many implants such as artificial joints and pacemakers are made of titanium, they occasionally break – but why? A researcher is investigating implant failure and how to prevent it.

News • Preventing maternal death

CT-based indicator helps predict life-threatening postpartum bleeding

Postpartum hemorrhage is a leading cause of maternal death. A new method could help predict which women experiencing severe bleeding after giving birth most likely need life-saving interventions.

News • Predictive phenotypes

Ovarian cancer: new insights into immune landscapes

Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.

News • Local impedance mapping

'Reading' heart scars for better treatments after a heart attack

An association between specific electrical patterns and structural characteristics of heart scars after a heart attack could offer a new approach for more targeted and effective arrhythmia treatments.

News • European system launch

Multi-light technology and CMOS sensor to advance gastroscopy

Fujifilm Healthcare Europe announce the European launch of the EG-860R routine gastroscope as the latest addition to their Eluxeo® endoscopy portfolio.

News • Proteomic-based score

AI measures tumor ‘stemness’ to predict cancer aggressiveness

A new AI-based tool measures cancer aggressiveness by analyzing the ‘stemness’ of tumors – their similarity to pluripotent stem cells. This could pave the way for new therapies.

News • Targeted drug delivery

Wireless NFC implant delivers chemotherapy deep into tumors

Korean researchers have developed a wireless implantable drug delivery system that enable chemotherapy drugs to penetrate deep into solid tumors—without harming surrounding healthy tissue.

Article • Reducing radiology's environmental footprint

Healing without harming: Radiographers' path to sustainable imaging

What if every radiographer could help combat climate change while performing their daily work? Following the congress theme of ECR 2025, experts revealed how small changes – from education initiatives to simple workflow adjustments – can collectively transform the environmental impact of radiology.

News • Barrier effect research

Using bacteria to improve microbiota resistance to pathogens

Microbiota composition can help prevent pathogenic bacteria from proliferating, known as the barrier effect. Now, scientists have identified seven bacteria involved, paving the way for new therapies.

News • Early detection of life-threatening conditions

Newborn immune profiling to improve neonatal care

Newborns, especially those born prematurely, are vulnerable to conditions such as sepsis. A new device profiles an infant’s immune function from a single drop of blood to improve neonatal care.

News • Appeal for tailored care approaches

Breast cancer: Study reveals ethnic differences in development and outcomes

When it comes to breast cancer, ethnic differences matter, putting some women at a significantly higher risk, a new study finds. Genetic ancestry should therefore be considered as a risk factor.

News • Amyotrophic lateral sclerosis

New insights on ALS onset opens paths to earlier treatment

New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.

News • Predictive models for fungal pathogens

Study: Climate change enhances threat of infection-causing fungi to Europe

The rise of pathogenic fungi is a real concern and is being driven by climate change. A new study predicts significant spread of certain fungal pathogens in Europe fuelled by rising temperatures.

News • Disposable sensor array

Face mask breath test could identify chronic kidney disease

Researchers incorporated a specialized breath sensor within the fabric of a face mask to detect metabolites associated with chronic kidney disease. Initial tests showed promising results.

News • Healthcare-associated infections and antimicrobial use

HAI: study reveals serious gaps in infection prevention and control

Healthcare-associated infections (HAI) are a threat to residents of long-term care facilities in Europe. A new study points to serious gaps in infection prevention and control measures.

News • Focus on mutation frequency decline

A new strategy to combat antibiotic resistance

Finding ways to target antibiotic-resistant bacteria is a scientific and medical priority. A consortium of researchers identified a compound capable of blocking a key protein for virulence, thus “disarming” the pathogenic bacteria.

News • Interferon response cancer-associated fibroblasts

Pancreatic cancer: Cell discovery opens up new research avenues

A newly discovered type of cells counteract tumor development and may therefore be a target for research into new treatments for pancreatic cancer, which is one of the deadliest forms of cancer.

News • HIV, TB, viral hepatitis, STIs

Europe not on track to reach 2030 health goals

Ending epidemics like HIV, tuberculosis, hepatitis and STIs by 2030 is a key health goal for Europe. Although progress has been made, many EU countries are not on track to meet the goals, experts say.

News • Fibroblasts promote tumor growth and spread

Study explores reasons behind high aggressiveness of pancreatic cancer

Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.

News • Adversarial robust image processing

Defense system protects medical digital twins from cyberattack

Medical digital twins can help predict diseases, but are vulnerable to cyberattacks that can lead to incorrect diagnoses. Researchers have developed a new defense system to address this threat.

News • Study on Staphylococcus aureus

Understanding bacterial antiviral defenses to tackle antibiotic resistance

In a new study, researchers show that the emergence of antibiotic resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.

News • Self-sustaining thermoelectric system

e-Tattoo detects infections from skin temperature

An international research team has developed an intelligent device capable of monitoring the skin continuously and accurately detect temperature variations associated with inflammation and infection.

News • Systemic cell rewiring

How midkine helps tumours evade immunotherapy

Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.

News • Cybersecurity protocol

Protecting wireless medical implants from being hacked

Cyberhealth threats such as the hacking of a medical implant are of real concern as technology moves toward smart, wirelessly connected implants. A new security protocol aims to protect these devices.

News • Parallel transmit

New MRI technique enables surgery in treatment-resistant epilepsy

Using ‘parallel transmit’ technique, researchers have found a new way to detect lesions in the brain of patients with treatment-resistant epilepsy in an MRI scan, without imaging signal dropouts.

News • 2025 TB surveillance and monitoring report

Childhood tuberculosis up by 10%: a wake-up call for Europe

Transmission of tuberculosis (TB) in the European Region is still ongoing, and immediate public health measures are needed to control and reduce the growing burden of the disease, experts urge.

News • Therapy innovation

Four advances that could change tuberculosis treatment

World TB Day raises awareness about tuberculosis and commemorates the discovery of the source bacterium M. tuberculosis. More than a century later, scientists still refine anti-TB strategies.

News • Medical evaluation via digital channels

Digitization calls for new skills in nurses

The work of a nurse is becoming increasingly digital. A new study shows that nurses need to expand their professional competencies beyond their traditional skills to adapt to these changes.

Article • Imaging modalities for quantifying myocardial blood flow

Nuclear cardiology – a nuclear perspective on matters of the heart

Nuclear cardiology is a specialised field in nuclear medicine that evaluates the heart function to help diagnosing conditions such as coronary artery disease and to assess treatment efficacy, whilst minimising invasive procedures like biopsies. More recently, clinicians have increasingly opted for nuclear imaging over endomyocardial biopsy to diagnose cardiac amyloidosis, allowing for earlier…

Video • Zwitterion research

Polymer coating to prevent blood clotting in medical implants

Researchers at the University of Sydney are using so-called Zwitterions to create a surface coating that could stop blood clotting in medical devices and implants like catheters and stents.

News • Cell-free tumor DNA analysis

Liquid biopsy to unlock breast cancer treatments

New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.

News • A closer look at the GI microbiome

“Gut-on-a-chip” predicts immunotherapy efficacy against melanoma

The gastrointestinal microbiome holds valuable information that can help predict whether immunotherapy will be successful against melanoma. A new “gut-on-a-chip” is designed to do exactly that.

News • Potentiator of AMR emergence and expansion

Diabetes as a driver of antibiotic resistance

Microbiologists have just shown that people with diabetes are more likely to develop antibiotic-resistant strains of Staphylococcus aureus, a leading cause of AMR-associated infections and deaths.

News • Micro Immune Response On chip (MIRO)

Replicating tumours to assess cancer immunotherapy efficacy

Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.

News • Researcher reveals vulnerability

New approach to crack persister tumour cells

Persister cells arise as a result of cancer treatment and are often responsible for tumour relapse. Researchers identified a distinctive feature of persister cells, paving the way for new treatments.

News • Concerning discovery

New antibiotics can develop resistance before even hitting the market

Two recent studies find that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.

News • Structural research

Researchers use “hallmarks of cancer” to understand tumour growth

“What is a tumour?” Researchers explore tumour architecture as a valuable source of information to understand tumour dynamics and predict its sensitivity to anticancer drugs.

News • Molecular mechanism discovered

Researchers find a way to stop harmful cells after cancer treatment

Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.

News • Research on medical communication

How healthcare can address vaccine hesitancy

The WHO lists vaccine hesitancy as a major threat to global health, but what exactly is it, and how can it be addressed? New research into these questions could open up ways to approach this issue.

News • Research on MRD in tongue cancer

Understanding chemotherapy resistance in oral cancers using organoids

Tongue cancer cells can become resistant to chemotherapy under certain circumstances. Investigating these mechanisms, researchers shed light on promising avenues toward new treatments for this cancer.

News • Precision oncology research

Breast cancer chemotherapy receives boost from localised magnetic fields

Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of breast cancer chemotherapy while reducing its harmful side effects.

News • Research into new therapies

How natural killer cells could fight leukemia more effectively

Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.

News • PET compound

New radiotracer lights up aggressive cancer tumours

A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.

News • New approach to combat treatment resistance

How chemotherapy affects ovarian cancer tumours

Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.

News • Hyperpolarised carbon-13 imaging

Metabolic MRI imaging distinguishes ovarian cancer subtypes

A new MRI-based imaging technique predicts the response of ovarian cancer tumours to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.

News • Tackling bacterial infections

Personalised phage therapy as alternative to antibiotics

The current rise in antibiotic resistance is once again sparking interest in phage therapy. Now, scientists developed a new tool that recommends the best possible phage cocktail for a given patient.

News • Emergence of E. coli

Studies reveal circulation of multidrug-resistant Enterobacterales in Europe

Two studies indicate warning signs about spread of bacteria resistant to the same group of antibiotics (carbapenems) in both healthcare and community settings across Europe.

News • Personalised antimicrobial susceptibility testing

AI to tackle antibiotic resistance in UTI treatment

New research has shown that using artificial intelligence (AI) can improve how urinary tract infections (UTIs) are treated, and help to address antimicrobial resistance (AMR).

News • Restoring antibacterial efficacy

New hydrogel helps overcome antibiotic resistance

In the laboratory, researchers increased the bactericidal effect of antibiotics 64-fold with the use of a new hydrogel. The material made the antibiotics effective even against resistant bacteria.

News • Drug adsorption

Nanoplastics can impair the effect of antibiotics, study finds

Nanoplastics are not only bad for the environment: A new study has shown that minuscule particles of plastic which enter the body also can impair the effect of antibiotic treatment.

News • Insights into ribosome variants

What keeps antibiotic-resistant bacteria from taking over?

It would seem that developing antibiotic resistance would give bacteria an immense advantage over their non-resistant counterparts. So, why do they not become dominant? New research may provide an answer.

Article • Between good practice and financial pitfalls

Delivering molecular pathology at lower costs

Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.

News • Predicting bloodstream infections

AI to tackle antimicrobial resistance, sepsis, in the ICU

UK scientists are harnessing the power of AI to assess the antimicrobial resistance of patients in intensive care units (ICUs) and identify sepsis-causing bloodstream infections.

Article • Molecular meets digital

Single-cell multiplex imaging: a powerful tool for digital pathology

Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…

News • Photothermal disinfection

Frying bacteria on implants with tiny gold radiators

New technology shows promise in protecting an implant against infections from resistant bacteria: By heating up small nanorods of gold with near-infrared light (NIR), the bacteria are killed.

News • Flexible device reduces biofilms

Bioelectronic patch 'electrifies' bacteria to prevent infections

Rsearchers developed a novel bioelectronic device that taps into the natural electrical activity of certain bacteria found on our skin, paving the way for a drug-free approach to managing infections.

Video • Cancer research

3D-printed tumor model reveals metastasis mechanisms

New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.

News • From silent to destructive

Exploring the two phases of Alzheimer's disease

Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

News • Hibernation

Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold

A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.

News • Unintended use of wearables

People with long Covid may "hack" their fitness trackers – for better or worse

Many aspects of long Covid are still poorly understood, so many sufferers have turned to self-monitoring via wearables. New research explores the benefits and drawbacks of this approach.

News • Increased risk of atherosclerosis

Cardiometabolic risk factors impair heart microcirculation

A new study reveals that cardiometabolic risk factors and subclinical atherosclerosis impair the function of the microvessels that irrigate the heart, potentially increasing atherosclerosis risk.

News • Antifungal resistance

Just a bit of mold? Why fungal disease should not be underestimated

While awareness for antimicrobial resistance (AMR) in bacteria is relatively high, fungal pathogens remain largely ignored – a blind spot with potentially dire consequences for global health.

News • Glioblastoma research

Brain scars from cancer treatment key factor for relapse

Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.

News • Reducing chemotherapy side effects

Trapping cancer cells in molecular 'cages'

Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.

News • MCMV based approach

Covid-19: vector vaccine offers long-term protection

Protection from established Covid-19 vaccines wanes relatively quickly. A new vector vaccine elicits prolonged immune response in animal models, and maintains its efficacy over extended time.

News • Antibiotic resistance control

Better tracking of AMR hospital bacteria

Infections caused by antibiotic-resistant (AMR) bacteria are a major issue in hospitals. A new technique aims to effectively track all types of relevant microorganisms simultaneously.

News • Bioactive polymer scaffold

New biomaterial regrows damaged cartilage in joints

A crucial component in joints, cartilage is notoriously difficult to repair. Now, US researchers have developed a promising bioactive material to regenerate cartilage in knee joints.

News • Lower dose, improve tolerability, retain efficacy

Prostate cancer therapy: benefits of therapy deescalation

Radiotherapy of prostate cancer often comes with side effects, causing some patients to discontinue treatment. New research shows the benefits of at lowering the dose over subsequent treatment cycles.

News • HAI research on MDR pathogen

New insights into hospital-acquired Klebsiella infections

Klebsiella is among the top three pathogens responsible for hospital-acquired infections (HAIs). Now, researchers discovered why the bacteria thrive in clinical environments.

News • Diffuse Large B-Cell Lymphoma (DLBCL)

Personalised simulations predict outcomes for blood cancer treatment

Using genomic sequencing data, researchers have created personalised simulations of individual patients that can quantify the impact of genetic mutations on cancer cell behaviour.

News • Improved infection protection

S. aureus: One step closer to a vaccine

Staphylococcus aureus is a leading cause of hospital-acquired bacterial infection, associated with over one million deaths worldwide each year. Now, researchers could be one step closer to a vaccine.

News • Circulating tumor extracellular vesicles

Metastatic prostate cancer: better monitoring with new liquid biopsy method

A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.

News • Adaptive mutability

How bowel cancer flips the switch to avoid immune detection

Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.

News • Evolution and host-specific adaptation

Pseudomonas aeruginosa: origins of an epidemic pathogen

How do pathogenic bacteria evolve to become epidemic? To find out, researchers examined DNA data from almost 10,000 samples taken from infected individuals, animals, and environments around the world.

News • The role of tissue stiffness

Pancreatic cancer: new approach could reverse chemo resistance

Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.

News • Tracking the spread and evolution of superbugs

Mapping the movement of people (and their pathogen travel companions)

Integrating bacterial genomic data with detailed human mobility data makes it possible to see how pathogens causing pneumonia and meningitis, move between regions and evolve over time.

News • Vital mechanism discovered

Promising approach to prevent breast cancer recurrence

Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.

News • Antibacterial protein as therapeutic target

Pancreatic cancer: new approach for immunotherapy

Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.

News • Integration of microanalysis chips

Establishing microfluidic control technology for blood testing devices

A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.

Article • Pros and cons of diagnostic techniques

Liquid biopsy vs. tissue biopsy: Getting the best of both worlds

Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.

News • Heteroresistance

Researchers discover new mechanisms behind antibiotic resistance

A new study explores the phenomenon of heteroresistance in bacteria, which is a key driver of antibiotic resistance. Two new discoveries could impact the development of future AMR strategies.

News • HAGIS project

German-Scottish teamwork against infectious diseases intensifies

Delegates from Hannover Medical School and the University of Glasgow have now signed a letter of intent to intensify their collaboration in the field of infection research.

News • “Defanging” dangerous bacteria

Pathoblockers: a future alternative to antibiotics?

Researchers have succeeded in developing “pathoblockers” that provide protection against the most common pneumonia-inducing pathogens, even if they are resistant to antibiotics.

News • Overuse in spite of case reduction

Study: newborns too often receive antibiotics for sepsis prevention

The rate of sepsis in newborns across Sweden has greatly decreased – however, the use of antibiotics for sepsis prevention has not. A new study points out the extent of the overuse.

News • Gene-snipping bacterial defenses

CRISPR: a promising tool to fight antibiotic resistance, but...

Could the 'gene scissors' CRISPR be used to make resistant bacteria susceptible to first-line antibiotics again? According to new reseach, yes – but the experts also point out serious caveats.

News • MRSA and other infections

Researchers develop vaccine to fight antibiotic resistance

Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.

Article • "Timely" study

Improved care after heart attack on AI-powered telemedicine platform

Coronary artery disease causes more than 1.8 million heart attacks each year in Europe. In most cases, rehabilitation helps the patients to return to their everyday life. But what happens once the patients have left the rehab clinic?

News • Nuclear medicine

Prostate cancer: New SPECT/CT technique for greater treatment precision

A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.

News • Infection control

Study highlights transmission risk of resistant bacteria in hospital sinks

A new study identifies hospital sinks as a source of bacterial outbreaks, highlighting the vulnerability for contamination. The researchers also point out the difficulties in stopping such outbreaks.

News • Cardiology consensus update

Atrial fibrillation: Agreement on standards for catheter ablation

Catheter ablation of atrial fibrillation is an important treatment option for heart rhythm maintenance and symptom reduction. Now, an international consensus statement reflects new techniques.

News • Proof of Concept funding

New research to starve resistant bacteria

Researchers are developing novel active substances designed to cut off the nutrient supply of resistant bacteria, effectively starving them to death.

News • Bioinformatics

New tool identifies chromosomal instability in cancer cells

A new detection tool is designed to contribute to improving tumour research and classification by identification and quantification of chromosomal instability in the nuclei of cancer cells.

News • Trends for different bloodstream infections

AMR: age and sex identified as risk factors

A person’s age, sex and location are correlated with the chance that they have a bloodstream infection that is resistant to antibiotics, according to a new study.

News • Follow the evidence

Optimising preventive measures to stop surgical infections

Why are we doing what we are doing to stop surgical infections? A new research review in the run-up to the ECCMID congress 2024 will look at improving preventive measures.

News • Bacterial blood infection diagnostics

New sepsis test gives doctors a two-day head start

A new way to analyze blood samples for suspected sepsis gives doctors test results two days earlier than before – a head start that could mean life or death for patients.

News • Focus on protein GDF15

Newfound mechanism could improve efficiency of diabetes treatments

Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.

News • Histological transformation

How lung cancer can transform into another type

Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.

News • Restoring responsiveness

New method could crack treatment-resistant prostate cancer

Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.

News • Persistence of K. pneumoniae and E. coli

Exploring long-time colonization with resistant enterobacteria

Once a patient’s body has been colonized by resistant bacteria, they can persist for a long time, a new study by the University and University Hospital of Basel shows.

News • Increasing cell visibility

Making cancer easier to find and destroy for the immune system

Researchers in Japan and the US have developed technology to robustly augment the amount of MHC class I molecules in cancer cells. This makes them easier to find and destroy for the immune system.

News • Molecular machines

Killing cancer cells: the 'jackhammer' approach

Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.

News • Research on resistant bacteria

Emergence of 'superbugs' is not just because of antibiotics

Researchers have analysed the rise of antibiotic resistance over the last 20 years in the UK and Norway, highlighting that antibiotic use is not the only factor in the increase.

News • Potency against multidrug-resistant bacteria

Synthetic antibiotic shows promise against serious chronic infections

A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against ‘superbugs’ such as MRSA, a new study shows.

Article • Technology-based therapy approach

Self-administered brain stimulation as a novel tool for depression treatment

Given the limited success of traditional therapies for depression, recent years have witnessed the emergence of technology-based interventions. One such intervention is transcranial electromagnetic stimulation (TMS).

News • Novel treatment strategy

Antibacterial nanoparticles to shorten tuberculosis therapy duration

A low-cost technology involving nano-sized antimicrobial compounds against tuberculosis has been developed by researchers at São Paulo State University (UNESP).

News • Imaging white matter damage

Advanced MRI detects brain changes after Covid-19

Using diffusion MRI technology, researchers in Sweden have found differences in brain tissue structure between patients with persisting symptoms after Covid-19 and healthy people.

News • CTC, ctDNA and exosomes in PCa management

Prostate cancer: Blood-based liquid biopsies yield valuable information

US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.

News • Cytokine reference

New “dictionary” reveals suprising complexity of immune responses

Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.

News • SCN tumor development

How prostate cancer grows aggressive to evade treatment

In a new study, UCLA researchers demonstrated how small cell neuroendocrine prostate cancer tumor cells can arise from less aggressive prostate tumors.

News • Susceptibility detection in Escherichia coli

How AI can detect antibiotic resistance in 30 minutes

A new deep-learning approach to AMR testing has been shown to detect antimicrobial susceptibility within as little as 30 minutes - significantly faster than current gold-standard approaches.

Article • Infection control

The strain typing technologies of tomorrow

Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.

News • PDAC subtype classification

Attacking the roots of pancreatic cancer

Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.

News • RENACER repository

Brain cancer tissue samples to gain new insights

A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.

News • Health communication on AMR

How to improve public understanding of “antimicrobial resistance”? Rename it

A new study on public health communication shows that the term commonly used to describe bacteria resistant to current medicines or antibiotics fails to stick in people’s memories.

News • Reduction of healthcare-associated infections

Study: Anti-Covid measures also prevent HAIs

The enhanced infection safety measures installed for the Covid-19 pandemic also had a beneficial effect on hospital-acquired infections (HAIs) overall, a new US study suggests.

News • Breakthrough against metastatic mammacarcinoma

New approach busts chemo resistance of TNBC breast cancer

A team of researchers from Vienna has discovered that dormant breast cancer tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein.

News • Replacement of unnecessary medicines

Are placebos fair game in healthcare? New study confirms

Using placebos in primary care to reduce overprescribing, conserve existing antibiotics and limit further resistance, is publicly acceptable, a new study shows.

News • After-effects of cancer treatment

Inflammation after radiotherapy may last for decades, study finds

After pelvic radiotherapy, patients may live with low-grade chronic inflammation of the lower intestine 20 years after the treatment, a new study shows.

Sponsored • Effects of the pandemic on patient care

Why safe blood collection is more important to nurses in 2023 than ever before

Being able to rely on a quality, safety-engineered device for blood collection allows staff to perform their tasks with the minimum of fuss. Nurse Constance Mak talks about the benefits of closed collection systems.

News • Fungus among us

What makes Candida auris such a sticky threat

Researchers at the University of Michigan have zeroed in on Candida auris – a fungus with the uncanny ability to stick to everything from skin to catheters – and made a startling discovery.

News • Radiation and immunotherapy

Promising combination therapy against "cold" breast cancer tumors

US researchers have discovered that radiation therapy combined with two types of immunotherapy can control tumors in preclinical models of triple negative breast cancer.

News • Infection treatment

Chemotherapy drugs to combat antibiotic-resistant bacteria

A new class of antibiotics, based on proven drugs used in cancer treatment, is now being developed by researchers at Linköping University. They could be used against resistant bacteria.

News • MEDICA Labmed Forum

Hot issues, current trends and innovations in lab medicine

From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.

News • Achromobacter research

Cystic fibrosis: new bacteria discovery could lead to better treatments

A new research breakthrough could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis.

News • Mapping prevalence across European hospitals

Sepsis: suprisingly common, underdiagnosed, and deadly

New research from Lund University has found a suprisingly high incidence of sepsis across hospital admissions. The experts say that the condition can be likened to an epidemic.

News • PFAS as risk factor

Researchers explore link between ‘forever chemicals’ and breast cancer

Can per- and polyfluoroalkyl substances (PFAS) increase the risk of breast cancer? A new study by US researchers examines the effects of the so-called “forever chemicals”.

News • Brain cancer reseach

Researchers reveal mechanisms that make tumours malignant

Brain tumour progression to a malignant state is believed to be the result of an intricate interplay between cancer cells and the tumour microenvironment. Greek researchers shed new light on the mechanisms.

News • Planetary health

Global analysis links antibiotic resistance increase to rising air pollution

Curbing levels of harmful air pollution could help reduce antibiotic resistance, according to the first in-depth global analysis of possible links between the two.

News • Hospital pathogen Acinetobacter baumannii

More appendages = greater adaptability

German bioinformaticians have now detected an unexpected diversity of certain cell appendages in the bacterium Acinetobacter baumannii that are associated with its pathogenicity.

News • Deep learning in imaging

Earlier detection of diabetes through chest x-rays and AI

A new AI model finds that x-ray images collected during routine medical care can provide warning signs for diabetes, even in patients who don’t meet the guidelines for elevated risk.

News • Women's health

Why obesity makes ovarian cancer more deadly

A new study led by researchers from the University of Notre Dame links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors.

News • Development of medical care

New research: how healthcare will change over the next 50 years

AI, robotics, climate change and more: Swedish researchers outline emerging technologies and trends that may define what the healthcare industry looks like in the next 50 years.

News • Joint implant material

Biodegradable gel shows promise for cartilage regeneration

A gel that combines both stiffness and toughness is a step forward in the bid to create biodegradable implants for joint injuries, according to new research from the University of British Columbia.

News • Study on gentle cleansers

Virus-killing properties of soaps: No need for the 'hard stuff'

Gentle cleansers are just as effective in killing viruses – including coronavirus – as harsh soaps, according to a new study from scientists at the University of Sheffield.

News • Brain cancer breakthrough

Can a virus help beat glioblastoma?

US researchers identified a potential breakthrough in glioblastoma treatment. Using a modified virus, they created a treatment that specifically attacks tumor cells, while leaving normal cells intact.

News • Researchers tie up loose ends

The ideal surgical knot (according to science)

Knots are a crucial part of surgery, but surprisingly little is known about how they work. To fill this gap, a team at EPFL started the first physics-based study on the mechanics of surgical knots, and exactly what properties influence their strength.

News • AMR threat

Global response to antimicrobial resistance 'insufficient,' new research finds

Governments around the world must do more to tackle the growing threat of drug-resistant infections, new research led by the University of Leeds suggests.

News • Chronic myeloid leukaemia

CML therapy response predicted by AI "crystal ball"

AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.

News • Molecular test for bacteria response

New method rapidly reveals antibiotic resistance

Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.

News • Algorithmic medical advice

Would you trust an AI doctor? Study reveals split in patients' attitude

A University of Arizona Health Sciences-led study found that more than 50% of people don't fully trust AI-powered medical advice, but many put faith in AI if it's monitored and guided by human touch.

News • Sustainability in cardiology

Finnish reseachers develop fully biodegradable ECG patch

A team at the Finnish research institute VTT has created a biodegradable ECG patch, aiming to pave the way to a more sustainable future for wearable electronic devices.

News • Independent genes

Cancer: Study sheds light on mysterious DNA rings

Tumors sometimes seem to take on a life of their own, with cancer genes “striking out” in ring shapes. An international research team has new insights into this phenomenon.

News • Strain mapping and antimicrobial properties

Smart coatings give early warning for implant failure

Newly developed “smart” coatings for surgical orthopedic implants can monitor strain on the devices to provide early warning of implant failures while killing infection-causing bacteria.

News • Oncology & Immunology

Study shows mechanism of PTEN-deficient breast cancer

A group of researchers has illustrated the mechanistic pathway for PTEN-deficient breast cancer and successfully tested a method of countering the downstream effects of immune system evasion by tumors.

News • Chemotherapy, testicular cancer

Gene scissors find target for testicular cancer therapy

Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors: Cisplatin is used successfully in the chemotherapy of testicular cancer.

News • Oncology & Cancer

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.

News • The "Rx" factor

GP burnout linked to higher opioid and antibiotic prescribing

When in doubt, write a prescription? New research links burnout in GPs to higher antibiotic and strong opioid prescribing, especially in more deprived areas of the North of England.

News • Protein controls resistance

Targeted approach holds promise to improve chemotherapy

Chemotherapy resistance is a main cause of treatment failure and death in cancer patients. Researchers from Brussels found how cancer cells protect themselves from the aggressive treatment.

News • Seniors’ use of antibiotics halved

Study shows benefits of antibiotic stewardship in UTI management

An international study has shown how a decision tool for health professionals has proved capable of halving the use of antibiotics against urinary tract infections while maintaining patient safety.

News • MR-Linac measures oxygen levels

One step closer to targeted real time treatment of hypoxic cancers

Imaging researchers have taken a major step towards their ultimate goal of identifying cancers that are starved of oxygen so that altered treatment can be used to target them more effectively.

News • MTX in the mix

Researchers develop novel therapy for vancomycin-resistant infections

Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).

News • Randomness as resistance strategy

Cancer response to chemotherapy: a game of chance?

Cancer cells have an innate randomness in their ability to respond to chemotherapy, which is another tool in their arsenal of resisting treatment, new research shows.

News • Novel therapeutic strategy

Chemogenetics for the treatment of challenging epilepsy cases

Scientists from Japan demonstrated, for the first time, a successful chemogenetic suppression of widespread epileptic seizures in macaque monkeys. Their findings represent an essential step towards clinical trials, and effective treatment for patients with severe epilepsy.

Sponsored • Orthopaedics

Hip arthroplasty for femoral neck fractures – but without the complications

Arthroplasty for femoral neck fractures has seen enormous progress in recent years, but complications due to infections are still a major problem. With good preparation and the right technique, however, orthopaedic surgeons can take away much of the horror of this scenario.

News • A chatbot to replace GPs?

ChatGPT does a surprisingly solid job at prescribing the right meds, but...

Researchers from the University of Liverpool have tested whether the AI-powered chatbot ChatGPT could be used to make decisions about prescribing patients with antibiotics.

Video • Foundation announces launch

Championing focused ultrasound in the UK

The newly founded UK Focused Ultrasound Foundation is dedicated to advancing the development and adoption of the technology, which can be used to non-invasively treat tissue deep in the body.

News • Infectious disease research

Hidden bacteria increases risk of antimicrobial resistant infection in hospital patients

Carriers of a specific bacteria have a 14% chance of developing an antibiotic resistant infection with 30 days of hospitalisation, according to new research from Amsterdam.

News • Systems biology

Lung cancer: new discovery could remove metastatic traits

A Korean research team successfully changed the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

Article • Promising approach

Focused ultrasound ablation for treatment of breast tumours

Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.

News • Unexpected reactivation

BYOB (Bring your own bacteria) as cause of hospital infections?

Some hospitalized patients’ infections may develop from their own bacteria, new research results suggest. The study in mice indicates that medical interventions can awaken dormant, hidden bacteria.

News • Making tumours susceptible to chemo

Breast cancer: target protein may hold key to therapy success

A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research.  

News • Patient-derived whole-tumor cell culture model

Breast cancer: New method finds the right therapy

Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.

News • Stress reaction in the body

Exploring heat and cold as cardiovascular hazards

Both hot and cold environments trigger a stress response and can lead to cardiovascular problems. Results of a new study are especially interesting in light of the current multiple global crises.

News • Antibacterial compound research

Developing antibiotics that target multiple-drug-resistant bacteria

Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.

News • Potential treatments for relapsing breast cancer patients

New technique for tracking resistant breast cancer cells

Scientists managed to identify and kill breast cancer cells that evade standard treatments in a study in mice. The is a step towards the development of new treatments to prevent relapse in patients.

News • Pacemaker cells in glioblastoma

How brain tumours keep the beat

Glioblastomas march to the beat of a different drum: researchers discovered a type of cells that act as pacemakers, driving the growth of the brain tumour and increasing its resistance.

News • Driving genes of AMR in focus

Tracking the global spread of antimicrobial resistance

An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.

News • Microbial keratitis prevention

'Smart contact lenses' to detect eye infections

A pioneering ‘smart contact lens’ to test the eye in a quick, non-invasive way could prevent deaths caused by fungal eye infections in developing countries.

Sponsored • Disease management

Multiplex Testing: A Solution to Manage Surge in Respiratory Illnesses as Concerns over “Multi-demic” Rise

Eunsin Bae, M.D. specializes in laboratory medicine and leads the Institute of Clinical Research at Seegene Inc. Her research focuses on microbiology, molecular biology, and hematology. Dr. Bae is currently working toward implementing a global clinical study and establishing an international network of clinical investigations.

Article • “Taiwan Excellence” at Medica 2022

Sustainable solutions for post-pandemic healthcare

Innovative gastrointestinal imaging, medical panel PCs with hygiene optimisation, smartphone-based diagnostic tools, and sustainable hardware setups: At Medica 2022, manufacturers from Taiwan again showed their capability to adapt and provide solutions for a world radically changed by the Covid-19 pandemic. Under the “Taiwan Excellence” banner, outstanding products from the island nation’s…

News • Increased infection risk

AMR: drug resistant bacteria can travel from gut to lung

A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.

Sponsored • Periprosthetic protection

Bone cements containing antibiotics for infection prophylaxis – quo vadis?

Periprosthetic infections and revisions are on the rise in Germany and worldwide, with significant consequences for affected patients as well as for the healthcare systems. Precisely because the number of patients at higher risk of infection in arthroplasty continues to rise, attention is increasingly focused on how this dreaded complication can be avoided.

Article • Tissue-engineered glioblastoma model

3D brain tumour in a dish to personalize cancer treatment

It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.

News • Tumor location as important growth factor

New molecular microscopy uncovers breast cancer spread

Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease.

News • Bioprinting in cancer

3D printing patient-specific tumours

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models.

Sponsored • OR equipment

Clinio series: All-in-one computer for use in hygienically sensitive areas

Nowadays, the operating theatre is networked and staff have access to a wide range of information and image data. With the Clinio, Rein Medical offers a medical all-in-one (AIO) computer that has been designed for use in hygienically sensitive areas.

Article • Detecting several different diseases

Multiplex diagnostics: next-generation techniques for new challenges

With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.

News • New treatment approach

Colon cancer: Overcoming chemotherapy resistance

Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.

News • Passive steerable instrument

Flexible needle for greater precision in surgery

Engineers from EPFL and the University of Strasbourg have developed a surgical needle whose trajectory can be corrected on the fly, thanks to a flexible tip controlled with a simple button.

Article • Patient care

Molecular Tumour Board for better decision-making

As more genomic alterations become targets for therapy, health institutions and hospitals are creating specialist Molecular Tumour Boards to support better decision-making for patient care. This evolving team, and its role, was highlighted in a presentation at the 34th European Congress of Pathology in Basel, Switzerland.

News • Menopause research

Hot flashes: a hazard for the heart?

Not just uncomfortable, but hard on the heart: Accumulating research suggests a link between hot flashes during the menopause and cardiovascular disease risk in women.

News • Insights into stem cell behaviour

Breast cancer: new mechanism of drug resistance discovered

Scientists in Italy discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells. They also devised an experimental therapy to bypass or prevent this.

News • Resistance building prevention

New test to reduce antibiotics in primary care

Antibiotic prescribing in primary care could be monitored using health insurance data. And reduced with a simple test.

News • How cancer spreads

Cancer metastasis: Breakthrough to lead to better treatments

Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.

News • Cancer research

Key function of important leukemia gene demystified

The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team now showed that EVI1's cancer causing effect relies on activating a single gene — the stem cell transcription factor ERG.

News • Covid-19

Preparing for another outbreak

What will the next pandemic look like? Health officials from across the globe gathered in Geneva in late August at a World Health Organization meeting to focus on how lessons learned from Covid-19 might best prepare civilization for the "next one."

News • Alveolar rhabdomyosarcoma

Promising new treatment for deadly pediatric tumor

Alveolar rhabdomyosarcoma is a rare pediatric tumor. For more than 40 years there has not been any new development regarding treatment. Research led by Prof. Dr. Anton Henssen at Charité University Berlin has now identified a new therapeutic option, using a drug that is currently under investigation for other types of cancer.

News • New therapy

Drug turns cancer gene into "eat me" flag for immune system

UC San Francisco researchers have developed a drug marking cancer cells for destruction by the immune system.

News • Streptococcus pneumoniae

Technique helps discover whether bacteria are antibiotic resistant

A new study could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae, which cause meningitis, are resistant to antibiotics.

News • Blood-brain barrier simulation

Artificial brain vessels advance drug testing

German researchers present a novel method for testing chemical agents that could help in the development of drugs against neurodegenerative diseases such as Alzheimer's.

News • Desperate cancer cells

How tumors mutate their way out of a crisis (and become drug-resistant)

Researchers discovered that cancer cells mobilize a SOS response when they are desperate to resist anticancer drugs. The team also came up with an anti-SOS approach that blocked the mechanism in mice.

Sponsored • Washer-disinfector series

Fully virucidal efficacy of Meiko TopLine proven in testing

The new washer-disinfector series exhibits comprehensive decontamination and disinfection performance against all human-pathogenic viruses, confirms accredited testing laboratory HygCen Germany GmbH.

News • High-glade glioma research

Understanding why deadly brain cancer comes back

A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.

News • Osteoarthritis help

Lab-made cartilage gel outperforms real thing in knees

A research team has created the first gel-based cartilage substitute that is even stronger and more durable than the real thing, offering a promising solution for patient suffering from knee pain.

News • Grafts

Where do clots begin?

Researchers at McMaster University create device to replicate conditions in blood vessels after grafts.

News • Greenhouse gas emissions

How climate change impacts human pathogenic diseases

A comprehensive assessment of scientific literature has uncovered empirical evidence that more than 58% of human diseases caused by pathogens, such as dengue, hepatitis, pneumonia, malaria, Zika, have been aggravated by climatic hazards.

News • Dexterity and motor skills

Robotic sensors could help transform prosthetics

A project to develop advanced sensors for use in robotic systems could transform prosthetics and robotic limbs. It aims to develop sensors which provide enhanced capabilities to robot.

Article • Outbreak prevention and management efforts

Infectious diseases: new challenges for EU monitoring

Avian flu, MERS, Covid-19, monkeypox: outbreaks of infectious diseases are getting more common in Europe. As a result, the EU must adapt its surveillance strategies and introduce more data-driven, interdisciplinary countermeasues.

News • Extended treatment

New trial doubles down on antibiotics against life threatening infections

Hospital patients who develop infections where 10% of sufferers die will be offered double the traditional course of antibiotics in a new trial.