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News • Antibacterial compound research

Developing antibiotics that target multiple-drug-resistant bacteria

Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.

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Sponsored • Periprosthetic protection

Bone cements containing antibiotics for infection prophylaxis – quo vadis?

Periprosthetic infections and revisions are on the rise in Germany and worldwide, with significant consequences for affected patients as well as for the healthcare systems. Precisely because the…

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News • COVID and E. coli

Futuristic coating for fabrics kills viruses

Researchers have developed an inexpensive, non-toxic coating for almost any fabric that decreases the infectivity of the virus that causes COVID-19 by up to 90 per cent.

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News • Before clinical use of antibiotics

Superbug MRSA arose in hedgehogs

A type of the antibiotic resistant superbug MRSA arose in nature long before the use of antibiotics in humans and livestock, which has traditionally been blamed for its emergence.

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News • Resistance mechanism discovered

How staphylococci protect themselves against antibiotics

The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat. Researchers at the University of Bonn have uncovered an…

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Article • Antibiotic resistance

Five-minute MRSA detection with aptasensor swabs

An international research team from Saudi Arabia, Germany, and Jordan has developed a novel pathogen aptasensor swab designed to qualitatively detect, within five minutes, any methicillin-resistant…

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News • A new tool to combat superbugs

Defeating antibiotic resistant bacteria with 'molecular tweezers'

Antibiotic resistant bacteria are a looming super threat – heralding a time when our drugs will no longer be effective against prevalent infections. Hospitals are already coping with treatment-resistant bacterial infections. Cognizant of the threat and thinking outside the box, BGU scientists and German and American colleagues have developed a pair of 'molecular tweezers' to destroy the biofilm…

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News • Teixobactin against superbugs

Researchers find 'resistance resistant' antibiotic

University of Melbourne researchers are finding ways to beat dangerous superbugs with ‘resistance resistant’ antibiotics, and it could help in the fight against coronavirus (COVID-19) complications. As bacteria evolve, they develop strategies that undermine antibiotics and morph into ‘superbugs’ that can resist most available treatments and cause potentially lethal infections. The…

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News • Disarming MRSA

Potent antimicrobial to fight staph infections

Research led by scientists from McMaster University has yielded a potent antimicrobial that works against the toughest infectious disease strains. The find could be the beginning of developing new therapeutics to combat drug-resistant infections. The discovery is important as it is directly related to the development of Staphylococcus aureus diseases, known popularly as staph infections, which…

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News • MRSA & Co.

Test to detect antibiotic resistance in less than 45 minutes

Scientists from Scotland are developing a low cost, rapid diagnostic sensor test which aims to show the susceptibility of bacteria to antibiotics within 45 minutes. Laboratory testing of samples can take up to two days and the new test aims to allow doctors to be able to prescribe the correct antibiotic to a patient for an infection more quickly. In a research paper published in the journal…

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Article • Combatting nosocomial infections

A&E Staphylococci POCT

Martin Möckel and Dorothee Riedlinger, from the Charité Medical University Berlin, Emergency and Acute Medicine Campus Virchow-Klinikum, and Campus Charité-Mitte report on POCT testing in the A&E Department to screen for Staphylococcus aureus colonisation of the nose or throat. People colonised with Staphylococci are at increased risk of developing a nosocomial, i.e. hospital acquired…

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News • Pathogenic microbes

Cigarette smoke makes MRSA superbug bacterium more drug-resistant

Cigarette smoke can make MRSA bacterial strains more resistant to antibiotics, new research from the University of Bath has shown. In addition cigarette smoke exposure can make some strains of Staphylococcus aureus – a microbe present in 30-60% of the global population and responsible for many diseases, some fatal – more invasive and persistent, although the effect is not universal across all…

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Article • Microbiology & hygiene

HAIs are one problem – MDROs another

In view of the increase of multidrug-resistant organisms (MDRO), the World Health Organisation (WHO) has declared antibiotic resistance one of the biggest threats to global health. MDROs have become a major problem particularly in hospitals. Professor Dr Georg Häcker, President of the German Society of Hygiene and Microbiology (DGHM) and Director of the Institute for Microbiology and Hygiene at…

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News • Epidemiology & economics

Bacterial resistance costs French hospitals up to 290 million Euros per year

A team of researchers from Versailles Saint-Quentin-en-Yvelines University (UVSQ), Inserm and Pasteur Institute has been able to provide for the first time an accurate estimate of both the incidence (annual number of new cases) and added direct cost of infections due to antibiotic-resistant bacteria in patients hospitalised in French hospitals during 2015 and 2016.

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Article • Differentiate and select

Myths and truths about antibiotics, antiseptics and vaccination

Sixty-two percent of Germans fear antibiotic resistance, according to a survey recently conducted by the German Federal Institute for Risk Assessment. ‘Patients colonised by multi-resistant pathogens are particularly scared. But many of these fears are rooted in misunderstandings,’ explained Professor Mathias Pletz at the Congress for Infectious Diseases and Tropical Medicine (KIT).

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Article • Infection control

Knowledge is one thing - implementation another

Insufficient knowledge of infection control, resulting in insufficient compliance, increases the risk of hospital acquired infections (HAIs) and multiresistant pathogens that put patients at risk. At the 2019 Annual General Meeting of the German Society for Hygiene and Microbiology e.V. (DGHM) in Göttingen, Professor Frauke Mattner, Senior Consultant at the Institute of Hygiene, Kliniken der…

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News • MRSA

Decolonization protocol can prevent dangerous infections

Antiseptic soap, mouthwash, and nose ointment after hospital discharge reduced infections and infection-associated hospitalizations due to MRSA in high-risk patients. Hospital patients who have methicillin-resistant Staphylococcus aureus (MRSA) can prevent future MRSA infections by following a standard bathing protocol after discharge. The Changing Lives by Eradicating Antibiotic Resistance, or…

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News • Alarming results

Antibiotic resistance spreads faster than previously thought

By studying fish raised in aquaculture, researchers from the Helmholtz Zentrum München, the University of Copenhagen and the University of Campinas in Brazil have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to the study published in the journal ‘Microbiome’, those mechanisms are more varied than previously thought. “In…

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Article • Infection control

Local antibiotics improve results

Hip and knee joint surgeries are among the most common procedures in orthopaedics and trauma surgery and complications can occur. Rare, but serious, among these is periprosthetic joint infection (PJI), which causes high costs in healthcare and stress for patients. PJI is caused by microorganisms that form a biofilm on the surface of the implant and, in this sessile state, they are difficult to…

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News • Research

Path to deadly sepsis varies by bacterial infection

Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. Scientists know little about the early stages of the condition; however, physicians must act fast. Every hour that passes without one or more of the few treatments available increases the risk of death.

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News • Hospital hygiene

Will resistant bacteria be the end of alcohol hand sanitizers?

Alcohol-based hand sanitisers have been a mainstay in hospital hygiene for decades. But now, strains of antibiotic-resistant bacteria show signs of overcoming these handwashing agents as well. Does this mean we should just stop sanitising our hands? Not so fast, say researchers from Melbourne – however, hospitals now need to re-think their strategies to protect their patients from deadly…

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Sponsored • Innovation

A real time saver at the highest level of molecular diagnostics – the eazyplex® platform!

This platform enables you to perform high class molecular diagnostics at an unbelievable speed. All assay run times are as short as 15 to 30 minutes, depending on the sample material. The lyophilised reactions are shippable and storable at room temperature and ready to use, with a shelf life of 18 month. Due to the robustness of the polymerase you don’t need any DNA extraction. The…

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Article • MRSA and refugees

Screening, isolation, hygiene equal money well spent

Comprehensive examinations of 143 refugee patients hailing mostly from Afghanistan and Syria, which were conducted between June and December 2015, showed a high prevalence of MRSA, ESBL and MDRGN upon hospital admission. The figures exceed not only those of the general population but, alarmingly, also those found in high-risk groups, such as residents of nursing homes or home care service…

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