Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
Scientists from Northwestern University have developed an injectable regenerative nanomaterial that helps protect the brain during the vulnerable window after a stroke.
Now, a research team has developed a novel diagnostic approach that enables the rapid and simultaneous detection of both antibiotic resistance and high virulence in Klebsiella pneumoniae.
Cardiovascular disease and depression do not co-occur by chance; the TO_AITION project aims to enable earlier diagnosis of comorbidity, better risk prediction and personalised treatment strategies.
To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.
Even minor functional impairments of the kidneys can have serious consequences for patients after major surgery. New biomarkers could help identify high-risk patients at an early stage.
Researchers from Osaka have developed a simple and efficient system for understanding the functions of specific norovirus genes, providing new avenues for developing antivirals and vaccines.
New insights into the intestinal nervous system – or "gut brain" – open new avenues for advancing therapies for allergies, chronic inflammatory bowel diseases and irritable bowel syndrome.
Researchers have developed a novel 3D-printable material that is both biocompatible and highly elastic. The technology could pave the way for artificial organs and improved drug delivery systems.
Highlights: iDplus Confidence – Sensitivity and Flexibility:Rapid microbial identification for research useIdentifies and classifies strains based on phenotype characteristicsSuperSpectra reduce the incidence of false positives and ensure robustness and reproducibilityOpen system allows the addition of new species/entries to the database or the creation of new databasesClustering allows…
Metal-organic frameworks (MOFs) serve as the basis for a novel type of MRI contrast agent, which the developers hope can outperform current agents while being less toxic for the patient.
After a bout of influenza or Covid, the risk of heart attack or stroke may rise dramatically, and chronic infections may increase the long-term risk of serious cardiovascular disease events.
Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…
A novel imaging solution, called PSMA PET scanning, can more effectively detect the recurrence of prostate cancer compared to standard methods, and is associated with improved survival outcomes.
An international project to create a ‘digital twin’ of the human immune system could help scientists finally tackle grand challenges such as autoimmune disorders and infectious diseases.
Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.
Scientists have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body’s immune response.
New insights on the mechanisms that cause “brain fog” in Long Covid patients: Researchers use a specialized brain imaging technique to identify a potential biomarker and therapeutic target.
TU München researchers discover how chronic cellular stress changes gut microbiome composition, promoting cancer development through altered lipid metabolism.
A squishy new ‘artificial cartilage’ material could improve arthritis treatments by releasing anti-inflammatory drugs in response to a flare-up.
The Pharmaceutical Automation and Digitalisation Congress (AUTOMA+) 2025 is a hub for decision-makers and digital innovators for exchanging insights on the integration of AI within pharma operations. To bring on the networking discussions, the Congress is held in Vösendorf, Austria on November 24-25.
An advanced imaging method that uses the natural glow of tissues could help detect subtle differences in the tissue’s biochemistry, offering a way to earlier detect colorectal cancer via endoscopy.
Studies have found that natural polysaccharides from a medical fungus endemic to Taiwan can not only effectively inhibit inflammation, but also fight the proliferation of lung cancer cells.
Tracer molecules serve to provide visual guidance in nuclear medicine, but a new molecule could give surgeons additional audio cues to help them locate prostate cancer tumors and metastases.
Denoising of diffusion-weighted MRI data creates sharper images – but does it actually lead to better diagnostic results? Researchers explored the impact of noise removal on detecting abnormalities.
A multicenter study involving leading hospitals across Spain, has confirmed that people with COPD show altered levels of specific metabolites in their blood.
Some medications can only be taken as an injection, which is often painful, unpleasant and inconvenient for patients. A new transport system could make it possible to swap these injections for pills.
After an infection with the coronavirus Sars-CoV-2, the virus is able to persist at low levels in the brainstem, new research finds. This helps explain some of the enduring neurological symptoms.
Dense calcifications are common in breast tissue, but not every finding in a mammogram is a precursor of cancer. New insights could lead to fewer benign biopsies and guide therapeutic development.
A new AI-based tool measures cancer aggressiveness by analyzing the ‘stemness’ of tumors – their similarity to pluripotent stem cells. This could pave the way for new therapies.
A new technique called photoacoustic computed tomography (PACT) offers a breast imaging alternative without the discomfort, high costs, or risk associated with the conventional evaluation methods.
What do the brains of newborns and patients with Alzheimer's disease have in common? Researchers have discovered a surprising shared trait - which might provide new insights into the disease.
A research team at the University of Geneva has identified two new proteins that regulate gene expression, a discovery that could pave the way for new cancer and brain disorder treatments.
Is osteoarthritis really an inevitable side-effect of an ageing body? New research challenges the idea of mechanical wear of joints as the cause of this painful condition.
New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.
After the Covid-19 pandemic, face masks have become less common. However, those who still need to wear a mask often suffer from discomfort due to restricted breathing. New research could change this.
Does having blood type A increase the risk of breast cancer? A new systematic review and meta-analysis involving more than 13,000 breast cancer patients suggests a connection.
Researchers incorporated a specialized breath sensor within the fabric of a face mask to detect metabolites associated with chronic kidney disease. Initial tests showed promising results.
Finding ways to target antibiotic-resistant bacteria is a scientific and medical priority. A consortium of researchers identified a compound capable of blocking a key protein for virulence, thus “disarming” the pathogenic bacteria.
Using an advanced PET scanner, US radiologists explore how cancer, neurodegenerative diseases and other systemic conditions, can affect the brain by assessing the impact on the blood-brain barrier.
Unprecedented insights into the inner workings of an early-stage lung tumor: An international research team describes a new method for 3D mapping cellular interactions in the tumor microenvironment.
Breast MRI has emerged as a powerful diagnostic tool, particularly for women with dense breast tissue where traditional mammography faces limitations. In her presentation at ECR 2025, radiographer Hanna Kalliomäki highlighted several technological advances transforming breast cancer detection and diagnosis. From time-saving abbreviated protocols and AI-assisted analysis to contrast-free…
Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.
Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.
New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.
RNA researcher Anastasia Khvorova, PhD, professor of RNA therapeutics at UMass Chan Medical School, will receive this year's Else Kröner Fresenius Prize for Medical Research on May 15, 2025. The award ceremony will be a part of the festive event together with the Fresenius SE & Co. KGaA celebrating the 100th birthday of Else Kröner, at the Städel Museum in Frankfurt am Main.
New research has revealed how Duchenne muscular dystrophy (DMD) also profoundly affects the brain, leading to cognitive and behavioural challenges that are very diverse and some could be reversible.
Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.
Researchers have developed ‘sponge-like’ microneedle patches that deliver bioactive ingredients and reduce inflammation in slow- and non-healing diabetic wounds.
Nuclear medicine specialists have successfully used the radiopharmaceutical Ga-68-Trivehexin from Trimt to accurately diagnose patients with pulmonary fibrosis and concurrent lung cancer.
Giving separated blood plasma improves outcomes in patients with traumatic brain injury (TBI) or shock, whereas unseparated or “whole” blood may be best for patients with traumatic bleeding.
Researchers have succeeded in producing sensors from single-wall carbon nanotubes that are suitable for detecting even minute changes in specific substances in the body, such as female hormones.
Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…
A new AI-enhanced technique makes breast cancer tissue “glow” on MRI scans. This not only improves breast cancer detection but also can help treat it more effectively, the researchers say.
Research on biliary tract cancer is advancing rapidly, ranging from targeted treatments to new drugs. However, the delivery of these advances to patients is lagging behind, new European studies find.
Researchers at the University of Sydney are using so-called Zwitterions to create a surface coating that could stop blood clotting in medical devices and implants like catheters and stents.
Promising insights into amyotrophic lateral sclerosis (ALS): New research links characteristic symptoms of the disease, such as motor impairment and respiratory issues, to sleep disorders.
The gastrointestinal microbiome holds valuable information that can help predict whether immunotherapy will be successful against melanoma. A new “gut-on-a-chip” is designed to do exactly that.
When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.
Newborns with heart complications can rely on their immune systems to regenerate, but adults aren’t so lucky. A new study explores this mechanism, paving the way for treatments after a heart attack.
A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.
A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.
In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
A new MRI-based imaging technique predicts the response of ovarian cancer tumours to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.
A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.
US researchers have developed a comprehensive deep learning AI model designed to more accurately identify and classify cells in high-content tissue images.
In the laboratory, researchers increased the bactericidal effect of antibiotics 64-fold with the use of a new hydrogel. The material made the antibiotics effective even against resistant bacteria.
It would seem that developing antibiotic resistance would give bacteria an immense advantage over their non-resistant counterparts. So, why do they not become dominant? New research may provide an answer.
A newly developed ‘biocooperative’ material based on blood can guide key processes taking place during the natural healing of tissues to create living materials that enhance tissue regeneration.
A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.
Dimensions: 700 × 1,920 × 850 mm (w × h × d)Weight: 330 kg, excluding data systemHighlights: iDplus Confidence – Sensitivity and Flexibility:Rapid microbial identification for research useIdentifies and classifies strains based on phenotype characteristicsSuperSpectra reduce the incidence of false positives and ensure robustness and reproducibilityOpen system…
How can innovations help to master challenges and demands in healthcare? This central question will be addressed at the Medica Health IT Forum, an established part of the programme at the trade fair.
New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
Misfolded proteins lead to Alzheimer's disease – but where do they come from? Using a particularly powerful imaging technique, Swiss researchers now uncovered a key mechanism.
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
Increasing implementation of robotic automation and AI will speed up scientific progress in science laboratories, according to a new study. The experts outline this process across distinctive levels.
Insulinomas are benign tumors in the pancreas, but can still cause problems for patients. A new imaging technique reliably detects these previously hard-to-find tumors, according to recent research.
The gut microbiome varies from person to person in terms of the bacterial species represented and their colonization density. Segatella copri is the most prominent germ. Researchers at the Helmholtz Centre for Infection Research goal to clarify its health significance.
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
While awareness for antimicrobial resistance (AMR) in bacteria is relatively high, fungal pathogens remain largely ignored – a blind spot with potentially dire consequences for global health.
Brain aneurysms cause around 500,000 deaths globally each year and can lead to stroke and disability. Now, researchers created nanoscale robots to manage bleeds in the brain caused by aneurysms.
Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.
Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.
Just a concussion? Head injury can lead to persistent symptoms, yet CT scans often fail to identify these cases. Researchers explore the potential of diffusion tensor imaging for better diagnostics.
A new type of contrast agent for use in both MRI and PET imaging has the potential to significantly enhance diagnosis and subsequent treatment, particularly for kidney diseases and tumors.
A crucial component in joints, cartilage is notoriously difficult to repair. Now, US researchers have developed a promising bioactive material to regenerate cartilage in knee joints.
A band-aid for the heart? US researchers have developed a new way to 3D print material that is at once elastic, tough, and shapable enough to fit a patient’s unique heart or joint defects.
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
Researchers have created a mucus-based bioink which can be used for 3D printing lung tissue. This advance could one day help study and treat chronic lung conditions.
Researchers were able to package fluorescent sensors for passage across the blood-brain barrier (BBB) in mice. This holds promise to advance Alzheimer’s disease diagnosis and treatment.
US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.
Diagnosis and monitoring medical conditions, including cancer, diabetes, heart disease, and infections: In this opinion article, Alix Joseph (Linxens) explores the potential of sweat analysis.
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
Using an advanced scanner, researchers have developed a technology that can detect the earliest changes in the kidney when scar tissue begins to form.
Staphylococcus aureus is a leading cause of hospital-acquired bacterial infection, associated with over one million deaths worldwide each year. Now, researchers could be one step closer to a vaccine.
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.
A new radiotracer enables positron emission tomography (PET) scans to be used for the first time to accurately pinpoint when and where tuberculosis (TB) is still active in a patient’s lungs.
A whole-body MRI scanner with a compact 0.05 Tesla permanent magnet has been developed that operates on a standard wall power outlet without radiofrequency or magnetic shielding cages.
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
Researchers are proposing a new device that uses blood to generate electricity and measure its conductivity, opening doors to medical care in any location.
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.
Researchers have succeeded in developing “pathoblockers” that provide protection against the most common pneumonia-inducing pathogens, even if they are resistant to antibiotics.
Researchers have developed a cutting-edge method for fabrication of customised pharmaceutical tablets with tailored drug release profiles, ensuring more precise and effective treatment options.
New research challenges assumptions about the origin of rheumatoid arthritis, which are probably too simple. The findings may point towards improved diagnostics of this painful autoimmune disease.
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.
Researchers are developing novel active substances designed to cut off the nutrient supply of resistant bacteria, effectively starving them to death.
With a field strength of 11.7 T, the Iseult MRI machine currently is the most powerful scanner of its kind. Now, the first images of a living human brain showcase impressive resolution.
Researchers have developed the 'iKnife', a smart scalpel that is able to recognise healthy tissue from brain tumour in seconds as it cuts, with more than 98% accuracy.
Not all medication can safely be taken together. Using a machine-learning algorithm, researchers predict interactions that could interfere with a drug’s effectiveness.
Researchers have developed a 3D-bioprinted, miniaturized chip to advance the understanding of cardiovascular disease and aid in the development of new precision treatments.
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
The loss of myelin sheaths in the brain is a hallmark of multiple sclerosis. Swiss researchers have now developed an MRI method that maps the condition of this nerve insulation layer more accurately.
Researchers in Japan and the US have developed technology to robustly augment the amount of MHC class I molecules in cancer cells. This makes them easier to find and destroy for the immune system.
Academic labs and biotech firms pioneer multi-cancer early detection with emerging technologies. Screening for multiple cancers with a simple blood or urinary draw could be a game-changer. Two research teams in particular have advanced the field.
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.
A team from the UK and Turkey have developed a contact lens with embedded micro-sensors which can detect changes in eye pressure - a possible indicator of glaucoma.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
A research team has developed a nanoparticle-based contrast agent with the properties necessary to successfully use MRI for targeted diagnosis of liver fibrosis.
An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.
A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against ‘superbugs’ such as MRSA, a new study shows.
Researchers have created a first-of-its-kind immune cell atlas of the developing lung, revealing coordination between the immune and respiratory systems much earlier than previously thought.
A new US study suggests a new way to personalize mental health care: They found compounds in the blood of people with depression and suicidal ideation that could be detected using a blood test.
Using AI and optoacoustic imaging, researchers have developed a new method to assess microvascular changes in the skin – and thus the severity of diabetes in the patient.
Using diffusion MRI technology, researchers in Sweden have found differences in brain tissue structure between patients with persisting symptoms after Covid-19 and healthy people.
US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
Neurobiologists in Sweden have discovered a way to partially restore communication between nerve cells in the brain after a stroke. This could lead to future treatments, the researchers say.
Researchers from the University of Birmingham have designed and developed a novel diagnostic device to detect traumatic brain injury (TBI) by shining a safe laser into the eye.
Using small blood vessels grown in the lab, researchers discover how vascular leaks leading to dementia and stroke emerge – and how this damage might be fixed.
A team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly.
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
Advances in positron computed tomography (PET) could lead to a more refined approach to the precise removal of brain tumors is on the horizon, experts from Poland point out.
A collaborative study, led by Cima Universidad de Navarra, has identified key epigenetic targets for the treatment of hepatoblastoma, the most frequent liver cancer in childhood.
A team of researchers has developed a visualisation tool that combines high-speed cameras and fluorescent injection to distinguish tumour tissue from normal tissue across cancer types.
What role should artificial life play in medicine? Researchers from Denmark and the US explore the potential of hybrid peptide-DNA nanostructures for diagnosing and treating diseases.
Researchers in Spain have developed a system using patient cells which represents the first 3D muscle model capable of replicating the damage caused by Duchenne muscular dystrophy (DMD).
A new class of antibiotics, based on proven drugs used in cancer treatment, is now being developed by researchers at Linköping University. They could be used against resistant bacteria.
Swiss scientists report that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across spinal cord injuries and guide nerves to reconnect to their natural targets.
Chemotherapy can be an effective means to fight breast cancer, but under certain circumstances, the treatment can cause dormant cancer cells to re-awaken, new research finds.
From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.
A new research breakthrough could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis.
In thyroid removal surgery, reliable discrimination between different tissues is crucial. US surgeons have evaluated how a new handheld device using mass spectrometry can assist them.
Endometriosis, which can cause debilitating pain each menstrual cycle, as well as infertility, is often misdiagnosed and misunderstood. An expert from Yale Medicine sheds light on the condition.
A team from Geneva demonstrates the value of imaging to detect the presence of tau protein in the brain to predict cognitive decline due to Alzheimer’s disease.
Researchers have unveiled a key mechanism of breast cancer cells to infiltrate lymph nodes. The discovery may lead to new metastasis-blocking treatments and improve patients’ lives.
Under the impulse of the European Commission, the in vitro diagnostic industry is developing emerging technologies to implement sustainable practices in medical laboratories. As sustainability has been a growing priority of the European Union (EU) in the last decade, ‘the medical technology sector, particularly the IVD sector, must comply with European legislation in this field like all other…
A new imaging method devised by German researchers offers a fast and cost-effective way to observe abnormal metabolic processes live in the MRI scanner.
Researchers from Queen’s University Belfast have created personalised 4D printed “smart” implants for breast cancer management - a first for this technology.
A Japanese research group has developed a method using iPS cell-derived mesenchymal stem cells (iMSC) to create cartilage spheroids, offering new possibilities for tissue repair.
An MRI invention from engineers at the University of Waterloo reveals better than many existing imaging technologies how Covid-19 can change the human brain.
French scientists discovered that CD4 T cells generated during immunotherapy are capable of remotely neutralizing tumor cells by producing interferon gamma (IFN-γ).
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
A group of researchers has illustrated the mechanistic pathway for PTEN-deficient breast cancer and successfully tested a method of countering the downstream effects of immune system evasion by tumors.
Getting vaccines to people who need them isn't always easy. Many vaccines require cold storage, making it difficult to ship them to remote areas that don't have the necessary infrastructure.
Genes are full of clues about a person's health and might also show the way for stroke recovery.
A new artificial intelligence model could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer.
Researchers at the University of Campinas and the Federal University of São Carlos in Brazil have developed an electrochemical sensor that detects Parkinson's disease at different stages.
US researchers have developed a way to use MRI scanning to map body cell metabolism, opening up new possibilities for detecting cancers and revealing if a tumor is responding to treatment.
A new kind of smart bandage developed at Caltech may make treatment of chronic wounds - for example caused by diabetes - easier, more effective, and less expensive.
French scientists are developing and testing a new vaccine to combat allergic asthma. Their latest study results pave the way for the organization of a clinical trial.
Researchers at the Universitat Autònoma de Barcelona (UAB) have developed a new type of nanoparticles inspired by the structure of amyloids, capable of neutralising the SARS-CoV-2 virus.
Scientists from Japan demonstrated, for the first time, a successful chemogenetic suppression of widespread epileptic seizures in macaque monkeys. Their findings represent an essential step towards clinical trials, and effective treatment for patients with severe epilepsy.
Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body’s molecules as triggers.
Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.
Scientists are developing a new kind of light-activated cancer treatments. This would work by switching on LED lights embedded close to a tumour, which would then activate biotherapeutic drugs.
Researchers have developed a Raman microscope that can acquire information hundreds of times faster than the conventional method. This could help expand its usefulness in biomedical applications.
In a world first, scientists from Singapore and Germany have shown that regenerative therapy to restore impaired kidney function may soon be a possibility.
It was previously assumed that bones lacked lymphatic vessels.Now, new research not only locates them within bone tissue, but demonstrates their role in bone and blood cell regeneration.
Dutch scientists have discovered how specialized immune cells can detect and remove cancers that are ‘invisible’ to the conventional defense mechanisms of the immune system.
New advanced therapies can alleviate or cure chronic diseases. But medical progress, such as the gene editing tool CRISPR, raises the question of how rights should be protected and balanced.
Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way. The method showed promising results against various cancers in lab tests on mice.
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
Engineers have developed an electronic patch that can give medical professionals unprecedented access to crucial information that could help spot life-threatening conditions.
Scientists from Singapore discovered a novel low-cost method of testing for cancers. The test sequences heated clinical samples to isolate cancer-specific signatures found in a patient’s blood.
Canadian researchers have developed a new method of killing brain cancer cells while preserving the tissue around it. A remarkable side-benefit: chemotherapy of the cancer suddenly becomes possible.
The first blood test to diagnose inflammation of the heart muscle (myocarditis) could be in use in as little as a year, following the discovery of a molecular signal in the blood.
Using a special type of MRI, researchers have uncovered brain changes in patients up to six months after they recovered from Covid-19, according to a study being presented at the annual RSNA meeting.
Swiss researchers developed a new MRI method to visualise metabolic processes in the body. Their objective is to improve the future diagnosis and treatment of heart disease.
Speed or accuracy? As far as Covid-19 tests go, this was the choice you had to make. In the future, this dilemma could be a thing of the past.
Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.
Researchers propose a new approach to identify cancerous tissue for surgical removal, based on real-time imaging of tissue oxygen concentration.
Researchers from Japan have developed a method to detect build-up of amyloid β in the brain, a characteristic of Alzheimer’s disease, from biomarkers in blood samples.
A newly developed capsule that tunnels through mucus in the GI tract could be used to orally administer large protein drugs such as insulin.
A research group has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.
A new device for diagnosing bone fragility invented by the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE) has been approved for marketing in the European Economic Area and Switzerland. The device is based on a new approach to assessing bone quality via blood sampling.
UC San Francisco researchers have developed a drug marking cancer cells for destruction by the immune system.
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
A team from Geneva has discovered a molecule that can identify the development of diabetes before the first symptoms appear.
A research team has created the first gel-based cartilage substitute that is even stronger and more durable than the real thing, offering a promising solution for patient suffering from knee pain.
The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
A new device, which doesn’t rely on immunosuppressing drugs, may assist efforts to develop an artificial pancreas to treat diabetes.
Researchers have identified an enzyme that is a promising new therapeutic target to combat the dangerous bacterial disease melioidosis.
A sensor identifies misfolded protein biomarkers in the blood. This offers a chance to detect Alzheimer's disease before any symptoms occur. Researchers intend to bring it to market maturity.
Researchers are seeking alternatives to gadolinium-based contrast agents (GBCAs) to help raise levels of patient safety. An open hybrid session at ECR in Vienna heard how research across several centres has been examining the options of new approaches to reduce reliance on GBCAs.
Cancer immunotherapy is a successful treatment form in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers found.
Research team led by Göttingen University combine two techniques to achieve isotropic super-resolution imaging.
To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.
Scientists shared one of the first high-resolution looks at the rabies virus glycoprotein in its vulnerable 'trimeric' form, revealing potential vaccine targets.
Newly engineered in vitro tumour models open ways to better understand the crosstalk between liver cancer cells and their microenvironment, researchers from Singapore found.
The research team Liver4Life has treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.
Researchers visualize brain inflammation using diffusion-weighted MRI. This detailed "X-ray" of inflammation cannot be obtained with conventional MRI, but requires data acquisition sequences and special mathematical models.
Latest developments in computational protein design enable the simulation of sequence and structural changes in proteins for creating novel agents in human medicine.
When a virus makes its way into the body, one of the immune system’s first responders is a set of pathogen-removal cells called macrophages. But they don’t all target viruses in the same way.
Glucose is absorbed from the foods we eat and fuels every cell in our bodies. But could it also power tomorrow’s medical implants? According to a team of engineers, it might.
A research team in Spain and the US has created 3D-printed acoustic holograms to improve the treatment of diseases like Alzheimer's and Parkinson's, among others.
Scientists from France and Belgium gained insights into the structure and function of a central liver protein: NTCP, a cellular-entry pathway for bile salts – but also for certain hepatitis viruses.
Silk-based material under skin changes color in response to oxygen, and in the future might be adapted to track glucose and other blood components.
Scientists at the La Jolla Institute for Immunology discover new drug target for severe asthma and fibrosis.
Researchers developed a new microfluidic chip with broad applications for detecting viruses, pathogens, bacteria and other biomarkers in liquid samples.
Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA, Würzburg researchers discovered.
Scientists have taken the first step to creating the next generation of wearable health monitors, which could monitor the body’s health by detecting the gases released from a person’s skin.
In order to better prevent and restore fertility and reduce the risk of sterility in cancer survivors, researchers investigate the mechanisms behind negative effects of chemotherapy.
An international research team has now found an approach to lower the activation of hepatic stellate cells (HSCs) and reduce the associated development of liver fibrosis.
When treating acute infections, health care providers must quickly identify the best antibiotics for fighting the infection. An automated system provides swift, accurate results for determining the best antibiotics at the right dose.
A platform for studying how the human immune system responds to hepatitis C infection by combining microfluidic technology with liver organoids could speed the hunt for a vaccine.
The advantages and limitations of the value of traceability chains in therapeutic drug monitoring will be explored during a key session at the EuroMedLab event.
Point-of-care testing (POCT) is a “win-win” scenario for patients and healthcare professionals in delivering care when and where it is needed, according to pathologist Adil Khan, MSc, PhD.
Modern medicine offers “peel and stick” solutions like nicotine or contraceptive patches to put right on the skin without needing to visit a doctor for an injection or procedure. Now, researchers have found that applying a topical ointment containing anti-tumor factor can increase the effectiveness of cancer treatment.
A wireless sensor could offer doctors a way to monitor changes in brain chemistry without requiring a second operation to remove the implant.
Synthetic correlated diffusion makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.
An anti-inflammatory drug incorporated into the coating around an implantable electronic medical device – such as a pacemaker – can reduce the body’s "foreign body" reaction.
An ECRC research team has introduced CRISPR-Cas9 into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.
Chromatograms from mass spectrometry feature characteristic peaks to signify the response of a target molecule. Artificial intelligence can help in the challenging task of identifying these peaks.
By employing artificial intelligence (AI) and robotics to formulate therapeutic proteins, researchers promoted tissue regeneration.
A new study has analyzed over 3000 proteins to identify which are causally linked to the development of severe Covid-19. This provides insight into potential new targets for treatment and prevention.
Scientists have developed a prototype sensor that could help rapidly measure adenosine triphosphate and lactate levels in blood samples, aiding in the rapid assessment of disease severity.
A newly discovered structure of chain-mail may explain the success of C.difficile at defending itself against antibiotics and immune system molecules.
Researchers in Zurich have developed a fluorescent orexin biosensor to observe on of the brain's signaling molecules "live" to gain insights into constant daytime sleepiness (narcolepsy).
Researchers have developed an inexpensive, non-toxic coating for almost any fabric that decreases the infectivity of the virus that causes COVID-19 by up to 90 per cent.
Researchers have identified a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome.
Researchers have developed a noninvasive and reagent-free technique for the efficient detection of COVID-19.
Researchers have developed a smartwatch that assesses cortisol levels found in sweat. The device opens new possibilities for personal health monitoring.
RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based compounds is far from being fully tapped, as RNA allows for entirely new therapeutic approaches.
Scientists have found that fat can help the pancreas adapt to excess sugar, thereby slowing the onset of diabetes.
For many years, antibiotic consumption in France was at an alarming level, resulting in a worryingly constant increase in antibiotic resistance However, a newly-enforced strict national plan appears to be having effect.
Scientists at have designed a quantum sensor to detect SARS-CoV-2 faster, cheaper, and more accurate than the current gold-standard technique, PCR.
Ever since the Abbe diffraction limit of conventional microscopy has been surpassed, super-resolution techniques have been diving ever deeper into the most miniscule details of molecular structures. We spoke with Prof. Dominic Zerulla, whose company PEARlabs is developing an imaging technique that sets out to push the boundaries once more – by looking at in-vivo nano-scale processes in motion.
