Researchers have developed a method to enhance the cellular features in pathology slides based on “structural color” – the same effect that gives peacock feathers their unique sheen.
Ultra-fast delivery, fewer side-effects: Results from the FAST-02 trial show that proton Flash therapy can be safely delivered to cancer patients with metastases in proximity to vital organs.
Detecting genetic mutations associated with lung cancer via laboratory tests can be expensive and time-consuming, and use up valuable tissue from small biopsy samples. A new approach aims to fix this.
A multicenter randomized clinical trial shows that real-time AI-assisted colonoscopy significantly improves adenoma detection among individuals at high risk for colorectal cancer.
A new portable ultrasound system could make breast imaging more accessible. The device generates high-res, 3D images of breast tissue, requires no expertise to operate and could be used at home.
Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.
Tiny algae-based robots guided by magnets could improve bladder cancer treatment by boosting delivery of chemotherapy drugs into tumours, results from a new study suggest.
Radiopharmaceutical therapy has already transformed care for neuroendocrine tumors and prostate cancer, but other tumor types still lack targeted treatment options. A new approach could change this.
Measuring radiodensity of visceral fat and muscle from CT scans, researchers have identified a new biomarker that may help determine the prognosis for patients with gastric cancer.
Advanced multiparametric MRI performed before kidney tumor surgery could help identify patients at higher risk for kidney function decline and chronic kidney disease after nephrectomy.
Ultrasound imaging is notoriously difficult to master, as the operator has to mentally arrange a 3D object from 2D images. A new approach using augmented reality (AR) could help speed up the training.
Blood tests show promise for detecting and monitoring cancer. A new method makes it possible to analyse samples containing as little as 5% cancer DNA, compared with the 15–20% required today.
Many people with breast cancer can avoid chemotherapy with a gene test, potentially sparing them side effects without increasing the risk of the cancer returning, a clinical trial has found.
A new type of peptide receptor radionuclide therapy (PRRT) appears to be safe in metastatic neuroendocrine tumor patients who have exhausted conventional treatment options.
Obesity may change how early-stage breast cancer becomes invasive, according to a new study. The findings could help improve physicians’ ability to predict and treat the disease.
A new AI model enables more efficient analysis of tissue samples taken from colorectal cancer tumours. This can help shorten diagnosis times, reduce costs, and improve diagnostic accuracy.
A simple, affordable urine test could detect early signs of lung cancer months, or even years, before symptoms appear, as well as monitor whether treatment is working and identify potential relapse.
Pancreas lesions are of diagnostic concern, as they may evolve into pancreatic cancer – but many never do. New research findings help explain how the transformation into a malignant state works.
A new ultrasonic needle for tumour diagnostics could be used to diagnose salivary gland tumours with far greater precision, a new study finds. The device also shows potential for other cancers.
New research reveals that testosterone slows glioblastoma growth—the opposite of the androgen’s effect on tumors outside the brain.
Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.
Researchers have used cryo-expansion microscopy to capture cytotoxic T lymphocytes destroying cancer cells in unprecedented 3D detail, opening new paths in immuno-oncology.
A new analytical method could improve how cancer treatments are designed – by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates.
Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.
Why does the same genetic mutation cause FCDII in some patients but not in others? Researchers developed organoids to model a brain malformation responsible for drug-resistant epilepsy in children.
A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.
To improve lung cancer detection, researchers have developed a new AI system that employs a dual approach to analyse CT scans – seeing both detail and context at the same time.
A new scientific study reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer on a national scale.
As women age, their breast tissue goes through major changes, with the most dramatic changes at menopause, but also during pregnancy and childbirth. A map reveals the impact on breast cancer.
Earlier detection, better outcomes: A new blood test for bowel cancer screening is designed to transform cancer outcomes by moving away from invasive or unpleasant methods.
A new review shows that chronic stress may actively drive cancer progression. Therefore, psycho-oncology should be part of standard cancer care, the researchers argue.
Our AI-powered pre-analytical quality-control platform that identifies and quantifies artifacts in WSIs promptly flagging artifacts like air bubbles, tissue folds, knife lines or out of focus to ensure consistent image quality.This in turn reduces the turnaround time and improves downstream accuracy. This solution is built for oncology diagnostics and clinical trials, our solutions deliver…
A new X-ray imaging technique could transform how hospitals analyse tissue samples, potentially speeding up diagnoses and improving outcomes for patients, a new study shows.
At this year’s European Congress of Radiology (ECR) in Vienna, Bayer presented new data on a contrast agent that could transform MRI imaging: gadoquatrane, which requires up to 60% less gadolinium than previous standard macrocyclic preparations whilst maintaining the same diagnostic accuracy. Prof. Hubertus Pietsch, Head of MRI & CT Contrast Agent Research at Bayer and one of the key…
Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.
Diagnostic imaging without actual images, but with sleek and shiny scanners; no more radiology and pathology departments, but virtual patient models and AI-enhanced surgical precision: At this year's European Congress of Radiology (ECR) in Vienna, two leading experts envisioned 2050 as a radically different future of medicine – less Grey's Anatomy, more Star Trek. They made it clear…
A PSMA PET/CT imaging test could safely halve the number of people who need a biopsy for suspected prostate cancer following inconclusive or reassuring results from an MRI scan, new research finds.
A hidden immune circuit in the uterus revealed: Researchers have discovered a crucial immune switch that sheds light on preeclampsia and early pregnancy failure.
Breast cancer screening could also be used to screen for cardiovascular disease, new research suggests: The risk of serious or fatal heart disease can be predicted with AI analysis of mammograms.
About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.
Functional brain radiosurgery is an application of stereotactic radiosurgery (SRS), representing its newest clinical field. It is a precise, non-invasive medical technique using focused ionising radiation to precisely target specific brain structures to modulate brain function for neurological disorders, psychiatric conditions, or intractable pain. The technology offers “precision without…
Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first.
Study shows women with stage IV breast cancer detected through screening have a 60% chance of survival ten years after diagnosis – compared to under 20% for those not detected through screening.
New research shows that using ultra-low field (ULF) MRI for breast imaging could offer an alternative to existing breast cancer screening methods and may reduce barriers to screening.
Clues in the CSF: Researchers have developed the first high-precision method that can theoretically diagnose common brain tumors in children and adolescents without surgery.
Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…
Transgender patients are largely invisible in breast cancer screening statistics – and many never receive an invitation to participate in screening programmes. Guidelines exist, but awareness among referring physicians remains low. Experts say radiology departments are best positioned to lead the change by creating inclusive environments and actively reaching out to this underserved population.…
Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.
Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.
A study of 200 lung cancer patients shows photon-counting CT cuts radiation by 66% and contrast agent by 27% - while delivering sharper images and better tumor detection than conventional CT.
MIT researchers have developed a miniaturized ultrasound system that could make it easier for breast ultrasounds to be performed more often, either at home or at a doctor’s office.
Beyond "one-size-fits-all": A new strategy that combines two types of PET scans can guide personalized radiotherapy for head and neck cancers, according to new research.
Scientists have shown that a type of laser similar to the one currently used in routine eye surgery could one day help surgeons remove unwanted tissues, such as tumours, with unprecedented accuracy.
Why do some tumours spread while others remain localised? Using colon cancer cells, scientists pinpointed the criteria that influence metastasis risk, and identified a way to assess its probability.
Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal cancer, research finds. This leads to better diagnostics and treatment.
A new study shows a significant survival benefit for patients with oropharyngeal cancers treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).
Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.
A sample of inequality: A new study shows that AI models can infer demographic information from pathology slides, leading to bias in cancer diagnosis among different populations.
Researchers have discovered that low physical activity is associated with a higher risk of lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition.
To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.
Radiotherapy is effective against prostate cancer but can cause side effects. Using AI, scientists found that images originally taken to help position patients could also predict rectal bleeding.
A novel AI-based method can distinguish between progressive brain tumours and radiotherapy-induced necrosis on advanced MRI. This could help clinicians more accurately identify and treat the issues.
Should women be told about their high breast density as part of mammography screening? While this may sound like an obvious choice, a new study warns of unintended effects.
Breast cancer – including aggressive variants – are surprisingly common in younger women, a new study shows. The findings strengthen the case for earlier, risk-tailored screening, the authors say.
Researchers developed an X-ray imaging method capable of revealing hidden features in a single shot. This could advance cancer detection, disease monitoring, security screening and material analysis.
Delivering a pathology service in resource-constrained locations and developing countries remains a challenge. Cost is a significant barrier, as is the availability of equipment, trained staff and technical and IT support can also hinder a desire from clinicians and pathologists to give their patients a high level of service to help their diagnosis and recovery. The subject was tackled in a…
A major new initiative aims to enable the development of advanced, specific and highly reproducible human in vitro models for greater understanding of disease and the acceleration of new medicines.
Dunlee will present its portfolio of integrated imaging solutions at RSNA 2025 in Chicago, Illinois. The company will demonstrate technologies for diagnostic and therapeutic imaging applications, including developments in Ultra-High Resolution and Photon Counting CT (UHR & PCCT), components for MRI-guided breast biopsies, and onboard imaging systems for radiation therapy.
Researchers have engineered a novel technique that uses a small balloon to gently widen the airways, and overcome the physical limitations of conventional bronchoscopy to reach deep lung tumors.
New hope for patients with neurological diseases: A combination of focused ultrasound and gene therapy enables targeted, nonsurgical control of seizure-relevant brain regions.
An international research team has discovered a promising new therapeutic approach for aggressive prostate cancer – in the thyroid gland.
Has organ imaging using ultrasound arrived at the same level as cross-sectional imaging? At the annual conference of the German Society for Internal Medicine (DGIM), PD Dr Corinna Trenker presented new technological developments and their diagnostic significance. Despite numerous innovations such as multiparametric protocols and AI support, she made it clear that the human factor remains one of…
Using a bioengineered bone marrow model, researchers were able to provide key new information on the efficacy and safety of CAR T-cell therapy for acute myeloid leukaemia (AML), the most common leukaemia in adults.
Researchers explore how ultrasound waves can be used to activate chemotherapy drugs only in targeted areas, offering a new path toward safer, more effective cancer treatment.
About 60% women in Europe enrolled in a national breast cancer screening programme who have a screening mammogram can feel reasonably confident that radiologists will be able to diagnose early-stage breast cancer. But what about the 30% categorised as having dense breasts, and the 10% who have extremely dense breasts? At the 2025 SBI (Society of Breast Imaging) Breast Imaging Symposium held in…
Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…
An international team has developed an AI model that brings together medical imaging data and clinical information to calculate the risk of breast cancer tumour recurrence more accurately.
Magnetic resonance imaging (MRI) holds great potential to spare men with suspected prostate cancer a painful biopsy. In our interview, Dr. Peter Seidensticker, Head of Medical Affairs Radiology at Bayer, outlines how MRI could be implemented as a first-line diagnostic.
GLP-1 receptor agonists are widely prescribed for individuals with diabetes and weight loss. However, these medications may adversely affect the interpretation of cancer imaging, new research finds.
Researchers have developed a tool to quickly quantify changes in the branches of mouse mammary glands. This could one day be used to detect early warning signs of breast cancer.
The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.
Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.
TU München researchers discover how chronic cellular stress changes gut microbiome composition, promoting cancer development through altered lipid metabolism.
University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.
A squishy new ‘artificial cartilage’ material could improve arthritis treatments by releasing anti-inflammatory drugs in response to a flare-up.
In metastatic EGFR-mutated non-small cell lung cancer (NSCLC), targeting residual disease through surgery can extend the benefits of EGFR TKI therapy beyond standard monotherapy, a new study finds.
Researchers explored two promising new biomarkers as potential radiotheranostic targets for endometrial cancer. This could help identify patients who are likely to respond to targeted therapeutics.
AI may be effective at detecting advanced breast cancer in mammograms, but current models still lack reliability. New research from Korea suggests that up to 14% of invasive cases are missed.
A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.
An advanced imaging method that uses the natural glow of tissues could help detect subtle differences in the tissue’s biochemistry, offering a way to earlier detect colorectal cancer via endoscopy.
Self-learning artificial intelligence approaches are offering a number of advantages for digital pathology when compared to established AI options. The benefits, which range from greater speed and capacitive flexibility to ‘wholly interpretable’ analyses, were outlined at the Digital Pathology and AI Congress in London.
A newly developed method to accurately quantify how much radiation is absorbed by the blood during cancer treatment could lead to more personalised, preventive, and safer radiotherapy.
Men assessed as healthy may still have an early form of prostate cancer. Using AI, researchers found signs that were missed in more than 80% of samples of men who later developed cancer.
Tracer molecules serve to provide visual guidance in nuclear medicine, but a new molecule could give surgeons additional audio cues to help them locate prostate cancer tumors and metastases.
An artificial heart valve made from SEBS, a new type of highly durable and biocompatible plastic, could be a step closer to use in humans, following a successful long-term safety test in animals.
Gadolinium-based contrast agents enhance visibility but also pose a significant health risk. A new AI-powered virtual MRI imaging technique is designed to offer a safer diagnostic approach.
The vaginal microbiome is a largely overlooked area of medicine that could dramatically improve outcomes for common infections, infertility and even cancer for millions of women, a new review finds.
Tumor vesicles may serve as early indicators of cancer and help monitor the effectiveness of treatments. Now, researchers discovered a new way to detect these vesicles.
How cancer cells survive the journey through the body to form metastases is still poorly understood. New insights into how cells survive intense physical stress could pave the way for new treatments.
Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.
A new, bacteria-based contrast agent illuminates tumors like a neon sign during surgery, enabling more precise resection and reducing the risk of recurrence.
Dense calcifications are common in breast tissue, but not every finding in a mammogram is a precursor of cancer. New insights could lead to fewer benign biopsies and guide therapeutic development.
Through quantitative real-time monitoring of cell spatiotemporal dynamics, or cell changes over time, electrical impedance spectroscopy (EIS) could be used to predict cancer growth.
A new AI-based tool measures cancer aggressiveness by analyzing the ‘stemness’ of tumors – their similarity to pluripotent stem cells. This could pave the way for new therapies.
At Medical Taiwan 2025, manufacturers attracted attendees with a wide range of innovations. We took a closer look at some of the most exciting companies and their products on display at the medical, health and care expo.
Korean researchers have developed a wireless implantable drug delivery system that enable chemotherapy drugs to penetrate deep into solid tumors—without harming surrounding healthy tissue.
Beyond the visible spectrum: A new LED-based hyperspectral imaging system shows promise for gastrointestinal cancer detection during endoscopy.
An implantable device could save diabetes patients from life-threatening hypoglycemia. Remaining under the skin, it can be triggered to release glucagon when blood sugar levels get too low.
Medical Taiwan has long been a showcase for cutting-edge healthcare solutions, but this year marked a pivotal moment. Visitors of the latest edition of the medical, health and care expo in Taipei witnessed a particularly noticeable step forward: the definitive transition of medical AI from promising research to actual clinical practice. Organized by the Taiwan External Trade Development Council…
More consistent TIL assessments, more accurate patients' prognoses: New research shows how AI sharpens pathologists' interpretation of tissue samples for malignant melanoma.
A new technique called photoacoustic computed tomography (PACT) offers a breast imaging alternative without the discomfort, high costs, or risk associated with the conventional evaluation methods.
Should tracheobronchial anastomoses be routinely wrapped following resection and reconstruction? A new study revisits this unresolved question in airway surgery.
Digital pathology software company Fujifilm Healthcare Europe and Ibex Medical Analytics, specializing in AI-powered cancer diagnostics, announce a formal partnership to support efficient and accurate cancer diagnosis.
In a new study, researchers have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells, to uncover a new therapeutic possibility for limiting breast cancer spread.
A new ‘liquid biopsy’ test can help fast-track lung cancer patients to receive targeted therapy up to two weeks earlier, while helping avoid further tests and treatments including chemotherapy.
Using nine different molecular biological technologies, researchers were able to precisely measure the properties of a melanoma tumor in four weeks and enable a precise treatment decision.
Tongue squamous cell carcinoma, the most common type of oral cancer, is a challenging target for immunotherapies. Researchers now identified five immunotypes to better predict treatment response.
Childhood cancer diagnosis times span from immediate to delays of several years, according to a new study. Young bone tumor patients are among the most affected by these delays.
Diagnosing breast cancer in women with extremely dense breasts often comes down to MRI, but the scans take long and are expensive. Research confirms that shorter protocols also yield accurate results.
With the introduction of boron neutron capture therapy (BNCT), Helsinki University Hospital offers a new radiation therapy method that can destroy cancer cells while sparing the surrounding tissue.
Does having blood type A increase the risk of breast cancer? A new systematic review and meta-analysis involving more than 13,000 breast cancer patients suggests a connection.
Using radiomics on mammograms of over 30,000 women, researchers have identified six breast texture patterns that may be associated with increased cancer risk.
A novel deep-learning approach automatically finds and classifies microcalcifications found in mammography images—bringing both accuracy and consistency to breast-cancer screening.
At the San Antonio Breast Cancer Symposium (SABCS), three experts presented new approaches and study results for the treatment of breast cancer in young women.
Using AI and extensive analyses of gene activity in tumours, researchers have found new, precise biomarkers to diagnose prostate cancer at an early stage through a simple urine sample.
Bringing diagnostics and therapy closer together - that is the basic concept behind theranostics. Through further development of its PET/MR scanners, Siemens Healthineers aims to advance this approach. Andreas Schneck, Head of the MRI Division at Siemens Healthineers, talks about the new system, which was also presented at the European Congress of Radiology (ECR) in Vienna, and its advantages in…
Molecular testing provides a more convenient, personalized way of monitoring of heart transplant recipients, according to insights shared at the Annual Meeting and Scientific Sessions of the ISHLT.
Dutch researchers have developed an AI tool to support Mohs surgery, a precise but time-consuming procedure to treat the most common form of cancer in the Netherlands: basal cell carcinoma.
Unprecedented insights into the inner workings of an early-stage lung tumor: An international research team describes a new method for 3D mapping cellular interactions in the tumor microenvironment.
A newly discovered type of cells counteract tumor development and may therefore be a target for research into new treatments for pancreatic cancer, which is one of the deadliest forms of cancer.
Radiation therapy is an effective component of many cancer treatments, but some patients experience severe side effects. A new study shows that hyperbaric oxygen therapy can provide long-term relief.
Pancreatic cysts (IPMNs) are seen as a precursor of pancreatic cancer. However, not all patients need to undergo surgery. A recent study may help patients with IPMNs to avoid unnecessary surgery.
Breast MRI has emerged as a powerful diagnostic tool, particularly for women with dense breast tissue where traditional mammography faces limitations. In her presentation at ECR 2025, radiographer Hanna Kalliomäki highlighted several technological advances transforming breast cancer detection and diagnosis. From time-saving abbreviated protocols and AI-assisted analysis to contrast-free…
Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.
Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.
Medical digital twins can help predict diseases, but are vulnerable to cyberattacks that can lead to incorrect diagnoses. Researchers have developed a new defense system to address this threat.
New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.
Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.
A new method to quickly and accurately analyze the structure of collagen in tissue shows promise to improve the diagnostics of cancer and other diseases.
The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.
Engineers developed a robotic probe that can generate high-resolution 3D ultrasound images from deep inside the gastrointestinal tract. The robot reaches its target with a unique kind of movement.
Nuclear medicine specialists have successfully used the radiopharmaceutical Ga-68-Trivehexin from Trimt to accurately diagnose patients with pulmonary fibrosis and concurrent lung cancer.
New findings show how AI-assisted mammography may not only reveal breast cancer, but can also assess calcium buildup in the arteries within breast tissue—an indicator of cardiovascular health.
Cryoablation, the destruction of malignant cancer cells by freezing them, is increasingly becoming an alternative to having conventional lumpectomy for patients diagnosed with early-stage, localised, low-risk breast cancer. Findings from numerous recent clinical trials show that cancer recurrence rates are very low and are comparable to breast conservation surgery (BCS).
Japanese researchers have developed magnetic nanoparticles that can be directed to tumors using a magnet and then heated with a laser to destroy cancer cells while sparing healthy tissue.
Researchers developed an advanced AI tool for automatic analysis of colorectal cancer tissue slides. The new model outperformed all predecessors in the classification of tissue microscopy samples.
Researchers developed an AI-based system which has has a broad ability to identify even subtle differences between medical images taken at different times, and to predict related outcome measures.
Using a prototype field cycling imager (FCI) scanner to examine breast cancer tissue, scientists distinguish tumour material from healthy tissue with more accuracy than current MRI methods.
Photon counting detectors along with novel algorithms allow for more precise 3D visualization of different tissues and contrast agents by capturing X-rays at multiple energy levels simultaneously.
Pancreatic cystic lesions – indicating an increased risk of pancreatic cancer – are an occasional incidental finding in routine computed tomography (CT) abdominal imaging. New research suggests that the superior image quality of photon-counting CT (PCCT) can help detect more of these lesions. At the RSNA annual meeting, an expert outlined the benefits and limitations of the imaging technique…
A new AI-enhanced technique makes breast cancer tissue “glow” on MRI scans. This not only improves breast cancer detection but also can help treat it more effectively, the researchers say.
The shimmering blue wings of a Morpho butterfly are not just beautiful to look at - they can also help make cancer diagnosis faster, more accurate and more accessible, new research finds.
New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.
Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting the aggressiveness of meningioma brain tumors and breast cancers.
Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.
When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.
Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.
Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.
“What is a tumour?” Researchers explore tumour architecture as a valuable source of information to understand tumour dynamics and predict its sensitivity to anticancer drugs.
Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.
The immune system of children reacts differently to cancer than that of adults. New insights into these differences have the potential to lead to new tailored treatments for children with cancer.
Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients’ cancer without aggressive surgery.
Steam eliminates wrinkles and germs, but can it destroy cancer cells too? A multisite clinical trial explores the potential of a water vapor system using steam to kill prostate cancer cells.
Liverpool physicists have developed a “diagnostic infrared wand” to more accurately predict the prognosis of oral cancer lesions than current H&E staining techniques.
Tongue cancer cells can become resistant to chemotherapy under certain circumstances. Investigating these mechanisms, researchers shed light on promising avenues toward new treatments for this cancer.
A premiere that brings hope for fertility restoration to men who underwent chemotherapy during childhood: Researchers reintroduced cryopreserved immature testicular tissue taken 16 years prior.
Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of breast cancer chemotherapy while reducing its harmful side effects.
In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.
A new type of photocurrent-responsive coating has been shown to shorten the bone-to-implant integration time after orthopaedic surgery to just two weeks.
Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.
Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.
Sakura Finetek Europe and MEDIPATH, a group of independent French pathologists, announced their collaboration to enhance cancer diagnostics and thus contribute to improved patient therapeutic management. This decision is part of an ongoing commitment to improving the quality of care provided to patients and in response to the significant increase in cancer cases over the last years.
When women are pregnant and nurse their babies, their bodies change to ensure the health of both mother and child. Researchers now surprisingly find that the intestine also changes completely.
Precise segmentation of anatomical structures greatly benefits cancer diagnosis. Using AI and deep learning methods, researchers are developing a high-precision 3D viewer software for medical image data.
US researchers have developed a comprehensive deep learning AI model designed to more accurately identify and classify cells in high-content tissue images.
A research team has found wearable organic x-ray sensors could be the answer towards safer radiotherapy protocols for cancer patients, reducing the debilitating side-effects of the treatment.
A new study shows how inherent variations in a cancer cell and its interactions with its surroundings mould its migration. The findings provide valuable insights into the processes behind metastasis.
New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.
A certain type of cells, called aneuploid epithelial cells, are usually associated with breast cancer. However, new research reveals that they can also be found in healthy women.
A new imaging technique reduces skin tone bias in breast cancer detection, improving visibility across diverse skin tones.
A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.
Royal Philips announced a major advance in radiation oncology with 510(k) clearance from the US Food and Drug Administration (FDA) for its new detector-based spectral CT radiotherapy solution.
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
Hyperbaric oxygen therapy (HBOT) treatments could offer relief to breast cancer patients who experience late toxicities following radiotherapy treatment. To date, the handful of completed clinical trials only produced inconclusive or contradictory results. Therefore, results from the latest trial, named HONEY (Effect of Hyperbaric Oxygen Therapy on Breast Cancer Patients with Late Radiation…
Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
Recent developments in deep learning techniques are enhancing clinical imaging quality and reducing radiation exposure for patients while also maintaining diagnostic accuracy. The latest AI (artificial intelligence) component to clinical imaging – referred to as deep learning reconstruction (DLR) – is having a particular benefit in paediatric imaging, according to Dr Samuel Brady from…
New technology shows promise in protecting an implant against infections from resistant bacteria: By heating up small nanorods of gold with near-infrared light (NIR), the bacteria are killed.
The year: 2034. Breast cancer patients benefit from perfectly personalised diagnostics and therapies. The tedium of follow-up treatments is a thing of the past, thanks to AI, augmented reality and robotics. Just a tale from the realm of science fiction, or could this soon be clinical reality? At the annual meeting of the German Senologic Society, Prof Dr Marc Thill from the Agaplesion Markus…
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.
New research has revealed that the connection between PFAS, and kidney damage may be tied to dysregulation of the gut microbiome.
Minimally invasive surgical interventions, innovative imaging and the use of AI: At the upcoming EUSOBI congress in Lisbon, experts present and discuss the latest advances in breast imaging. We spoke with Tanja Brycker from Hologic ahead of the event about new trends in women’s health, the company’s investment in innovation and education, and what the future of mammography looks like with the…
Miniature robots often lack the strength to transport instruments for endoscopic microsurgery. But what if they worked together? Scientists have pursued this idea to perform a surgical procedure.
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
A bit more mucus in the nose, a little less air in the gut: Even small changes can be important when planning proton therapy against cancer. A new workflow allows for an adapted irradiation every day.
A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.
Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.
Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.
A new method of analysing the crystals in dehydrated blood could lead to a quicker, cheaper and less painful technique to diagnose, early detect, and monitor prostate cancer.
Radiotherapy for breast cancer is always associated with the risk of damage to organs or surrounding tissue. A new positioning system, which has now been patented by the Hamm-Lippstadt University of Applied Sciences (HSHL), positions the breast far away from the upper body and thus increases the distance to the organs at risk. The medical device called "X-Akt Mamma RTX" is now set to be…
Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.
Breakthrough for telemedicine: Surpassing a distance of 9,300 kilometers, surgeons from Hongkong and Zurich successfully performed an endoscopic procedure in an animal model.
Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.
Combining risk markers, systematic evaluation of MRI images and AI, researchers aim to predict the risk of prostate cancer more accurately than before. This could save many patients from a biopsy.
A new type of contrast agent for use in both MRI and PET imaging has the potential to significantly enhance diagnosis and subsequent treatment, particularly for kidney diseases and tumors.
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
Dermatologists could benefit from a new algorithm that can help recognize patients with a highly aggressive form of basal cell carcinoma (BCC) of the face.
Researchers discovered islands of highly potent immune cells in the vicinity of glioblastomas. This may open up prospects for new therapies for these aggressive brain tumours.
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.
A surgical technique called total mesometrial resection (TMMR) is associated with better outcomes than current treatments. A new study shows a significantly lower risk of disease recurrence and death.
New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.
Medical AI is advancing gastrointestinal endoscopy – but what happens when it contributes to a medical error? Legal experts are pioneering efforts to develop guidelines on medical AI liability.
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.
Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.
A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).
Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.
Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.
In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.
Stiffness in tissues can be a valuable indicator of cancer formation. Now, researchers have developed a microscopic probe to perform histology at the single cell level inside the human body.
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
A three-part ‘multiparametric’ MRI of the prostate is standard of care in the UK for patients suspected of having prostate cancer. Now, a study shows two-part scans are sufficient for diagnosis.
Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
Osteosarcoma is the most prevalent malignant bone tumor. Now, researchers have developed a machine-learning model to predict the density of viable tumor cells after surgery and chemotherapy treatment.
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
A new detection tool is designed to contribute to improving tumour research and classification by identification and quantification of chromosomal instability in the nuclei of cancer cells.
A new bioelectronic sensor enables continuous monitoring of bladder function. This could be a game-changer for people with paralysis, spina bifida, bladder cancer or end-stage bladder disease.
A clinical trial has revealed the effectiveness of '3D mammography' in reducing by almost half the incidence of interval breast cancer appearing between two rounds of screening.
A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.
A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.
