News • Tailored chatbot
Customized ChatGPT to advance digital pathology
New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.
Search for: "cancerous tissue" - 250 articles found
News • Tumour infiltrating lymphocyte measurement
Breast cancer: AI tool predicts which DCIS cases become invasive
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
News • Focus on microproteins
Researchers find potential target for liver cancer vaccine
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
News • Research on physical conditions
Exploring the link between obesity and cancer risk
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
News • The role of tissue stiffness
Pancreatic cancer: new approach could reverse chemo resistance
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
News • Iontronic technology
Slowly but steady gets the brain tumour
Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.
Article • Challenges and opportunities
Molecular pathology in Europe: in search of standardization
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
Sponsored • All in one scan
World's First Total-Body PET/CT with 194 cm Axial FOV installed in Europe
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
News • A question of liability
Who’s to blame when AI makes a medical error?
Medical AI is advancing gastrointestinal endoscopy – but what happens when it contributes to a medical error? Legal experts are pioneering efforts to develop guidelines on medical AI liability.
Article • Pros and cons of diagnostic techniques
Liquid biopsy vs. tissue biopsy: Getting the best of both worlds
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
News • Hydrogel catalyst
Breaking down alcohol in the body: Researchers develop "detox gel"
Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.
Article • Advancements in endoscopy
Enhancing diagnosis and disease monitoring for ulcerative colitis
Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.
News • Clear cell renal cell cancer
Same-day imaging for ccRCC kidney cancer with new PET agent
A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).
News • Three-dimensional tissue processing
Pathology performs leap into 3D with AI
Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.
News • 6.5 million European funding
Fighting cancer with artificial cells and tissue
Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.
News • Opportunity for new treatment approaches
Atherosclerosis and cancer share surprising similarities, study finds
In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.
News • Novel probe assesses cell stiffness
A 3D endo-microscope for early cancer diagnosis
Stiffness in tissues can be a valuable indicator of cancer formation. Now, researchers have developed a microscopic probe to perform histology at the single cell level inside the human body.
News • Research on biomechanics
Tumour 'softness' can drive aggressiveness of breast cancer
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
News • Mechanistic subtypes
The telltale traces long Covid leaves in the blood
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Article • Pharmaceutical research
Boosting biomarker detection with digital pathology
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
News • Microbial influence on treatment
Study explores the role of bacteria in cancer
Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.
News • Promising secretory granules
New micromaterial to fight cancer with nanoparticle-targeting
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
News • Biparametric scan
Prostate cancer screening: two-part MRI is enough, study shows
A three-part ‘multiparametric’ MRI of the prostate is standard of care in the UK for patients suspected of having prostate cancer. Now, a study shows two-part scans are sufficient for diagnosis.
Article • Prostate cancer treatment
MR-guided radiotherapy: a potential game changer
Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
News • Omitting axillary lymph node removal
Breast cancer trial explores benefits of less extensive surgery
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
News • Osteosarcoma model
Bone cancer prognosis enhanced via deep learning
Osteosarcoma is the most prevalent malignant bone tumor. Now, researchers have developed a machine-learning model to predict the density of viable tumor cells after surgery and chemotherapy treatment.
News • BRCA1 and BRCA2 malfunctions
Targeting 'exhausted' immune cells to prevent breast cancer
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
News • Bioinformatics
New tool identifies chromosomal instability in cancer cells
A new detection tool is designed to contribute to improving tumour research and classification by identification and quantification of chromosomal instability in the nuclei of cancer cells.
News • Implant and app
New device monitors bladder fullness
A new bioelectronic sensor enables continuous monitoring of bladder function. This could be a game-changer for people with paralysis, spina bifida, bladder cancer or end-stage bladder disease.
News • 3D mammography
Trial shows benefits of digital breast tomosynthesis in breast cancer screening
A clinical trial has revealed the effectiveness of '3D mammography' in reducing by almost half the incidence of interval breast cancer appearing between two rounds of screening.
News • Promising study
Pre-operative PET-MRI to improve breast cancer treatment
A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.
News • Tumor proliferation insights
Computational model simulates biomechanical growth of breast cancer
A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.
News • Potential for screening and treatments
Study links bacteria subtype to colorectal cancer growth
A specific subtype of a microbe commonly found in the mouth has been identified that is able to travel to the gut and grow within colorectal cancer tumors, driving cancer progression.
News • Noninvasive stratification
Multiplex PET helps doctors 'see' bowel cancer
Multiplex PET imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, according to scientists in Glasgow.
News • Tissue analysis tool
'Smart scalpel' to help remove brain tumours
Researchers have developed the 'iKnife', a smart scalpel that is able to recognise healthy tissue from brain tumour in seconds as it cuts, with more than 98% accuracy.
Article • Key findings of latest survey
Women’s health: solutions for a growing problem
Awareness of the importance of women’s health is on the rise, but many challenges remain: At ECR 2024 in Vienna, we spoke with Hologic about their continued evaluation of healthcare efforts for women. At the congress, the company also shared how AI could be used to mitigate the effects of medical staff shortage.
News • Interpretable machine learning system
AI to detect colorectal cancer from pathology slides
Researchers work on the first prototype that applies AI to colorectal diagnosis. The prototype achieved a diagnostic acuity of 93.44% and a sensitivity of 99.7% in the detection of high-risk lesions.
News • Accurate detection and removal
Radioguided surgery to treat metastatic lymph nodes in prostate cancer
Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.
News • Personalised oncology
New platform to significantly reduce cancer drug testing and screening time
In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.
Article • Imaging in characterisation and classification of tumour types
Taking a closer look at breast cancer
Breast cancer has no “one size fits all” therapy approach: subtypes differ significantly in malignancy, progression, and treatment response. Therefore, the more is known about the type of carcinoma in a patient, the better the outcome. At the annual scientific EUSOBI meeting in Valencia, Dr Ramona Woitek pointed out the potential of novel imaging techniques and computational image analysis…
Article • New system combines nanotechnology and ultrasound
Reducing over-treatment of rectal cancer
An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.
News • Metastasis susceptibility
How chronic stress spreads cancer
Chronic stress can have a significant impact on health, from an increased risk for heart disease to a greater susceptibility of cancer metastasis. New research points out the underlying mechanisms.
News • Research on radiation interaction
Lung tissue model to increase cancer radiotherapy safety
Cancer patients receiving radiotherapy run the risk of injuring their lungs. This can lead to conditions like pneumonitis and fibrosis. A new cell-by-cell model can help make treatments safer.
Article • Imaging controversial
MRI breast cancer screening of high-risk women: benefits outweigh drawbacks
Breast MRI is increasingly being used as a primary breast cancer screening exam for young women. It brings benefits in women with dense breasts, who are at an elevated risk of developing breast cancer. The technique is also being ordered as a supplemental screening exam following mammography or breast ultrasound for women of all ages at high risk. But use of breast MRI as a screening tool is…
News • Pan-cancer proteogenomics
Characterizing the immune landscape in cancer
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
News • MRI, DR, mammography
High-end imaging equipment for NovaLife Polyclinic
On 9 December 2023, NovaLife Polyclinic, with over 15 years of experience in the private healthcare sector in Timișoara, proudly inaugurated its state-of-the-art branch in the vibrant capital city of Bucharest.
News • Molecular method
Low-dose PEM imaging to transform breast cancer detection
A new breast imaging technique provides high sensitivity for detecting cancer while significantly reducing the likelihood of false positive results, according to a new study.
News • Portable diagnostic tool
Breast cancer detection: New program tracks tumour heat
Researchers in Singapore have developed an AI-based software to assist in the early detection of breast cancer. Using thermal imaging, the program assesses the malignancy of a tumour.
News • Restoring responsiveness
New method could crack treatment-resistant prostate cancer
Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.
Article • During lumpectomy
Fluorescence-guided surgery identifies breast cancer in margins
Breast surgery is a traumatic experience for a woman, no matter whether breast-conservation surgery (BCS) or a mastectomy. Trauma levels are greatly enhanced, if pathological evaluation findings of an excised breast tumour following a lumpectomy suggest that additional cancer may still be in the margins, and a second surgical procedure is required. A new system with the ability to accurately…
News • Accelerated sample analysis
Digital pathology cleared for use in cancer screening programmes
Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.
News • Blood-based diagnosis of glioblastoma
Sparing brain cancer patients from undergoing risky surgery
A simple blood test could help diagnose patients with glioblastoma, the deadliest form of brain cancer, sparing them from undergoing invasive and highly-risky surgery, report UK researchers.
News • Machine learning in sample analysis
Lab-trained pathology AI meets real world: ‘mistakes can happen’
AI models are highly capable in analysing tissue samples – as long as conditions are lab-perfect. Add a little contamination, however, and diagnostic accuracy goes out the window, a new study shows.
News • Mammacarcinoma research
Study pinpoints breast cancer ‘cells-of-origin’ in high-risk women
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
News • Men's health
Gynaecomastia linked to heightened risk of death
Men with gynaecomastia (non-weight-related enlarged breast tissue) may be at heightened risk of an early death before the age of 75, suggests the first study of its kind.
News • Urea-powered machines
Nanorobots to reduce bladder tumours by 90%
New research demonstrates how tiny nanomachines could greatly reduce bladder cancer by precisely targeting the tumour and attacking it with a radioisotope carried on their surface.
News • Diagnostic imaging collaboration
Canon Medical Systems and Olympus team up for endoscopic ultrasound
Canon Medical Systems Corporation and Olympus Corporation announced that they have reached an agreement to collaborate on Endoscopic Ultrasound Systems, and presented a new imaging system.
News • Water exchange detection
New MRI-based method measures tumor malignancy
An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.
News • Point-of-care diagnostic platform
Inhalable sensors for early lung cancer detection
Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.
News • "Gene scissors" vs. sickle cell disease
FDA approves first CRISPR/Cas therapy
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
News • CTC, ctDNA and exosomes in PCa management
Prostate cancer: Blood-based liquid biopsies yield valuable information
US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.
News • Tissue oxygenation
Photoacoustic imaging for better diagnoses of ovarian cancer
Researchers and clinicians at Washington University in St. Louis found a way to improve diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes.
Article • Knowledge gaps in gender medicine
Covid-19 and sex: higher mortality of male patients
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
News • Using low-frequency electromagnetic fields
New method can detect early-stage breast cancer in two minutes
University of Waterloo researchers are pioneering a method to detect breast cancer in women early enough for them to receive life-saving treatment.
News • Flexible materials for imaging
'Bendy' X-ray detectors could revolutionise cancer treatment
New tissue-equivalent materials developed at the University of Surrey could pave the way for a new generation of flexible X-ray detectors, with potential applications in cancer treatment.
Article • Latest advances
Lab-on-a-chip systems in 2023: The micro-lab revolution
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
News • PDAC subtype classification
Attacking the roots of pancreatic cancer
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
News • Ultraviolet cell visualisation
'Seeing' cancer though the eyes of a butterfly
Inspired by the enhanced visual system of butterflies, researchers have developed an imaging sensor to “see” into the UV range for differentiating between cancer and normal cells.
News • RENACER repository
Brain cancer tissue samples to gain new insights
A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.
Article • Need for diversity in training datasets
Artificial intelligence in healthcare: not always fair
Machine learning and AI are playing an increasingly important role in medicine and healthcare, and not just since ChatGPT. This is especially true in data-intensive specialties such as radiology, pathology or intensive care. The quality of diagnostics and decision-making via AI, however, does not only depend on a sophisticated algorithm but – crucially – on the quality of the training data.
News • Good killer cells
Cellular immunotherapy: a new approach against cancer
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
News • Glioma imaging
PET imaging for more effective treatment of aggressive brain tumors
Advances in positron computed tomography (PET) could lead to a more refined approach to the precise removal of brain tumors is on the horizon, experts from Poland point out.
News • Deep learning refinement
Colorectal cancer: AI tool improves diagnostic accuracy
Researchers from Finland have developed an artificial intelligence tool for automatic colorectal cancer tissue analysis that outperforms prior methods.
News • Fluorescence lifetime imaging
New technique for distinguishing tumour from normal tissue
A team of researchers has developed a visualisation tool that combines high-speed cameras and fluorescent injection to distinguish tumour tissue from normal tissue across cancer types.
News • Detection of lumps
New robot could help diagnose breast cancer early
A team at the University of Bristol has developed a robot manipulator that could carry out clinical breast examinations. The developers hope the device will revolutionise breast health monitoring.
News • After-effects of cancer treatment
Inflammation after radiotherapy may last for decades, study finds
After pelvic radiotherapy, patients may live with low-grade chronic inflammation of the lower intestine 20 years after the treatment, a new study shows.
News • Autonomous medical needle steering
A tiny robot to maneuver through living lung tissue
A team from UNC has developed a steerable lung robot that can autonomously maneuver the intricacies of the lung, while avoiding important lung structures.
News • Insulin and oxygen production
An implantable device for injection-free diabetes control
Engineers from MIT are developing a device containing insulin-producing cells and a tiny oxygen-producing factory to keep the cells of diabetes patients healthy.
News • Injury of non-cancer cells identified as trigger
Breast cancer recurrence: Could chemotherapy cause what it's trying to stop?
Chemotherapy can be an effective means to fight breast cancer, but under certain circumstances, the treatment can cause dormant cancer cells to re-awaken, new research finds.
News • MEDICA Labmed Forum
Hot issues, current trends and innovations in lab medicine
From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.
News • Detecting tumors and metastases
Nanoparticles deliver double strike against cancer
A new nanocomplex renders a tumor harmless – and, on top of that, it trains the immune system to detect and eliminate metastases.
News • Intratumoral approach for hard-to-treat glioma
Microdevices implanted into tumor to help treat brain cancer
A new type of microdevice could offer new ways to treat brain cancer. The shape and size of a grain of rice, it is implanted into a tumor to study the effects of ongoing therapies.
News • Lifetime changes unraveled
Researchers track the process of breast cancer formation
Where are the beginnings of breast cancer? A team of researchers at Kyoto University has revealed the mechanism by which breast cancer is formed in the cells of mammalian epithelium.
News • Biomarker-based predictions
AI drives precision oncology for colorectal cancer
For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).
News • PFAS as risk factor
Researchers explore link between ‘forever chemicals’ and breast cancer
Can per- and polyfluoroalkyl substances (PFAS) increase the risk of breast cancer? A new study by US researchers examines the effects of the so-called “forever chemicals”.
News • Tissue identification
Mass spectrometry pen put to good use in thyroid surgery
In thyroid removal surgery, reliable discrimination between different tissues is crucial. US surgeons have evaluated how a new handheld device using mass spectrometry can assist them.
Article • RFA, MWA, CRYO and IRE under scrutiny
Thoracic interventions: new tools in the arsenal
Experts presented state-of-the-art and emerging techniques to treat chest tumours and discussed common issues in the management of pneumothorax at RSNA 2022. Current ablation methods in the thorax include radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation (CRYO), irreversible electroporation (IRE) and pulsed electric field.
News • Brain cancer reseach
Researchers reveal mechanisms that make tumours malignant
Brain tumour progression to a malignant state is believed to be the result of an intricate interplay between cancer cells and the tumour microenvironment. Greek researchers shed new light on the mechanisms.
News • BPE in dense breasts
Breast cancer: elevated MRI enhancement identifies higher risk
A machine learning model found that background parenchymal enhancement (BPE) on breast MRI is an indicator of breast cancer risk in women with extremely dense breasts.
Article • Breast cancer diagnostics
Precision pathology: an AI-led alternative to molecular diagnostics
Experts have highlighted how precision pathology using Artificial Intelligence can provide an effective alternative to molecular diagnostics. This, say a team from the Karolinska Institutet (KI) in Stockholm, Sweden, can also offer multiple advantages within a clinical setting and support risk stratification.
News • Protein alterations in rare cancer
‘Rosetta stone’ of sarcoma research to help personalise treatment
An 'encyclopaedia' of protein alterations in soft tissue sarcomas could open the door to a new era of understanding and treatment for this group of rare cancers.
Article • Supplemental imaging
The next breast screening advancement: Contrast-enhanced mammography
With the recent recommendation changes from the European Council in 2022, how radiologists screen for breast cancer is changing. Mammography has long been an essential technology in screening for breast cancer, and in the recommendations the Council formally recognized the advantages of digital breast tomosynthesis (DBT). This landmark acknowledges the research on and benefits of DBT, advocating…
News • Wearable for monitoring
Breast cancer: In-bra ultrasound scanner to improve early detection
A new device, designed by MIT researchers, could detect breast cancer earlier. The scanner, which can be incorporated into a bra, could allow more frequent monitoring of high-risk patients.
News • Magnet-controlled tentacle
Tiny surgical robot could transform cancer detection, treatment
A tiny robot which can travel deep into the lungs to detect and treat the first signs of cancer has been developed by researchers at the University of Leeds.
News • Lung cancer, cardiovascular disease
AI uses low-dose CT data for mortality prediction
AI can use data from low-dose CT scans of the lungs to improve risk prediction for death from lung cancer, cardiovascular disease and other causes, a new study finds.
News • Proof-of-concept research
Researchers reverse chemotherapy-related fertility loss
A new study by investigators from Brigham and Women’s Hospital demonstrates the potential for restoring fertility when the ovaries have stopped working.
News • Women's health
Why obesity makes ovarian cancer more deadly
A new study led by researchers from the University of Notre Dame links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors.
News • 3D placenta model
"iPlacenta" could transform healthcare in pregnancy
A placenta on a chip developed at the University of Dundee has the potential to transform research into life-threatening conditions in pregnancy.
News • Research into fat cells
Healthy adipocytes keep breast cancer at bay
Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer. According to the experts, adipocytes play a vital role here.
News • Real-time tumor profiling
AI tool decodes brain cancer’s genome during surgery
Scientists have designed an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery — critical information that can guide treatment decisions.
Article • Flow cytometry
Detecting and measuring nanoplastics in the blood stream
Plastics are a part of everyday life, and an increasingly concerning factor of global environmental pollution. They also have infiltrated our bodies as microparticles (MPs) and nanoparticles (NPs), found even in placentas supporting foetal life. And they are in our blood. Now, researchers in Spain have developed a new method to detect and measure nanoparticles in human peripheral blood that is…
News • Promising trial results
Radiotherapy boost cuts breast cancer treatment time by at least one week
Treatment times for radiotherapy could be reduced for some early breast cancer patients, according to a trial led by University of Cambridge and The Institute of Cancer Research, London.
News • Nuclear imaging marker
Renal cell carcinoma: New radiotracer improves detection and differentiation
A new PET tracer, 89Zr-DFO-girentuximab, can accurately detect a type of kidney cancer called clear cell renal cell carcinoma and differentiate it from other types of kidney tumors.
Article • State of the art and latest advances in technology
Robotic assistance in the operating theatre
Surgical robots are becoming widespread in operating theatres, delivering accuracy and safety. An overview of the main systems, principal operators, the market and European initiatives in this field.
News • "In-beam MRI"
Radiation therapy: proton trajectory made visible
For proton radiation therapy against cancer, there is yet no direct method for mapping the beam range during dose delivery. A new method devised by Dresden scientists could help.
News • Molecular and immunofluorescence imaging
Orion: A new tool for diagnosing cancer
Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.
News • Mysterious mechanism solved
Researchers discover how bowel cancer 'blinds' the immune system
A mystery which has stumped bowel cancer researchers for decades, has been solved by scientists at the Cancer Research UK Beatson Institute and University of Glasgow.
News • Diffusion-tensor and correlated diffusion imaging
New MRI technique captures Covid-19’s impact on the brain
An MRI invention from engineers at the University of Waterloo reveals better than many existing imaging technologies how Covid-19 can change the human brain.
News • Folate receptor exploitation
PET imaging: new discovery to help detect brain tumours
Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumours, researchers from the University of Turku report.
Article • Progress, limitations, and opportunities
Precision oncology: incredible potential, but not a miracle cure
Unanswered questions are hampering clinicians in their efforts to get the best out of a precision medicine approach for their patients. Speaking at the Genomics and Precision Medicine Expo in London at the end of May, cancer educator Dr Elaine Vickers said the benefits of being matched to an investigational drug remain questionable for most people with advanced cancer.
News • HSNCC treatment stratification
Head and neck cancer: using organoids for personalized therapy
Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).
Article • 21-day radiotherapy
A safe and effective “shortcut” for early breast cancer treatment
Patients with early-stage breast cancer who have an elevated risk of having tumour recurrence now have the option to take a course of radiotherapy following breast conservation surgery that is only three weeks long, half the time of conventional radiotherapy treatment.
News • Independent genes
Cancer: Study sheds light on mysterious DNA rings
Tumors sometimes seem to take on a life of their own, with cancer genes “striking out” in ring shapes. An international research team has new insights into this phenomenon.
News • Research on mini organs
Organoids bring new insights into liver cancer
Dutch scientists have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer.
News • Using portable ultrasound imaging
AI helpful in triaging breast masses in low-resource areas
AI can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer, according to a new study. This could prove useful for triage in low-resource settings.
Sponsored • Fully automated, IVDR-compliant Tissue-Tek Genie®
Advanced tissue staining meets standardisation
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
News • Oncology & Biomedical Technology
New treatment option in bone cancer: gene therapy combined with chemotherapy
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
News • Oncology & Immunology
Researchers find new IgE antibody targeting skin cancer
A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.
News • Oncology & health informatics
Colon cancer: AI tool predicts survival, treatment response
A new artificial intelligence model could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer.
News • Radiation protection in the healthcare sector
Female health workers need better radiation protection to minimize breast cancer risk, find researchers
Women working in health care who are regularly exposed to radiation from X-rays and other imaging procedures need better ionizing radiation protection.
News • Prevention of blood cancer
Research identifies new target that may prevent blood cancer
An international coalition of biomedical researchers has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.
News • Chemotherapy, testicular cancer
Gene scissors find target for testicular cancer therapy
Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors: Cisplatin is used successfully in the chemotherapy of testicular cancer.
Article • Digital breast tomosynthesis (DBT)
New EU recommendations for breast screening enhance opportunities for early detection
Mammography has been an essential imaging technology for breast cancer detection for decades. As the industry has continued to innovate, one advancement in mammography has particularly changed the landscape of breast imaging: digital breast tomosynthesis (DBT), also known as 3D mammography.
News • Imaging equipment
Dunlee unveils oncology bundles at ECR 2023
Dunlee unveiled its new oncology bundles onsite at ECR. The bundles combine components that have been tested and verified to work together so clinicians can offer state-of-the-art onboard Cone Beam CT (CBCT) in facilities.
News • Metabolic activity diffusion imaging
New MRI technique reveals cells’ energy activity in organs and tissues
US researchers have developed a way to use MRI scanning to map body cell metabolism, opening up new possibilities for detecting cancers and revealing if a tumor is responding to treatment.
News • SWIR for intraoperative tumor delineation
Combining machine learning with multispectral infrared imaging to guide cancer surgery
A UK research team has developed a new technique that combines machine learning with short-wave infrared (SWIR) fluorescence imaging to detect precise boundaries of tumors.
News • Visualization of radiopharmaceutical distribution
A low-cost lensless radiomicroscope for nuclear medicine imaging
A novel imaging modality that can visualize the distribution of medical radiopharmaceuticals with very fine resolution has been developed and successfully tested.
News • Fluorescence-guided surgery
"Lighting up" brain tumours for better surgical removal
A new real-time imaging technique that uses a type of infrared light has, for the first time, been used during surgery to differentiate between cancerous tumours and healthy tissue.
News • DBT vs. standard digital mammography
Huge study shows: Tomosynthesis better at breast cancer detection
In a study of over a million women, digital breast tomosynthesis (DBT) showed improved breast cancer screening outcomes over screening with standard digital mammography alone.
News • Secondary tumours
Scientists discover new way to help prevent breast cancer ‘time bomb’
Scientists have discovered why breast cancer cells that have spread to the lungs may ‘wake up’ following years of sleep - forming incurable secondary tumours.
News • Tissue tension measurement
New ultrasound method could lead to easier disease diagnosis
A new ultrasound method that can measure the level of tension in human tissue for the first time - a key indicator of disease - has been developed by researchers from the University of Sheffield.
News • Augmented reality system
AR-powered free-hand, real-time needle guidance for prostate cancer diagnosis
Researchers demonstrate a HoloLens AR system that enables accurate, flexible needle guidance for transperineal prostate interventions such as biopsy, focal laser ablation, and brachytherapy
Article • Cervix, vulva and vagina
More certainty with methylation tests for early detection of cancer
A second-generation lab test for early detection of cervical cancer is the most recent addition to Oncgnostics’ portfolio. In particular, the company’s solution will help women in countries with limited cancer screening. Moreover, new research on the early detection of vulval and vaginal cancer might soon enable the development of tests for these cancers.
Video • Potential for all-in-one endoscopic surgical tool
Soft robot for 3D bioprinting inside the human body
Researchers at the University of New South Wales unveil prototype device that can directly 3D print living cells onto internal organs and potentially be used as an all-in-one endoscopic surgical tool.
News • Health impact of PFAS
Study: “forever chemicals” disrupt key biological processes
Exposure to a mixture of chemicals called PFAS - also known as 'forever chemicals' - leads to alterations in biological processes associated with a broad range of diseases, a new study finds.
News • New treatment insights
Successful cure of HIV infection after stem cell transplantation
A new study confirms that haematopoietic stem cell transplantation can be used to cure patients with HIV infections. This third successful case gives new insights into the underlying processes.
News • Research on iron-dependent cell death
Liver cancer: Ferroptosis could open new therapeutic avenues
Researchers in Frankfurt have now been able to show how ferroptosis can be used to make immunotherapies against liver cancer more effective in mice.
Video • Foundation announces launch
Championing focused ultrasound in the UK
The newly founded UK Focused Ultrasound Foundation is dedicated to advancing the development and adoption of the technology, which can be used to non-invasively treat tissue deep in the body.
News • Fluorescence-guided surgery
Leading bone cancer scientists aim to improve surgical techniques
New research will bring together scientists from across the globe to accelerate fluorescence-guided surgery for bone cancer patients. The upcoming trial is focused on the dye indocyanine green (ICG).
News • Imaging study shows
Breast MRI effective at detecting cancer in dense breasts
Compared to other common supplemental screening methods, breast MRI was superior at detecting breast cancer in women with dense breasts, according to a new study.
News • Systems biology
Lung cancer: new discovery could remove metastatic traits
A Korean research team successfully changed the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.
News • Primary tumor or metastasis?
Deep learning and radiomics for precise differentiation in brain tumors
The distinction between primary tumors and metastases can be made quickly and accurately in brain tumors using radiomics and deep learning algorithms, a new study shows.
News • Metastasis research
Some cancer cells can lose their ability to migrate
In a new study, researchers from Kanazawa University show how some intestinal cancer cells lose their ability to spread as they divide and can be eliminated as the cancer grows.
Article • Promising approach
Focused ultrasound ablation for treatment of breast tumours
Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.
Video • Mini-bones from the lab
Toward a personalized approach of bone cancer research and therapy
Researchers generated human mini bones in the lab which mirror the composition and function of human bone - a step toward the development of future patient-tailored models of bone cancers and tumors.
Article • Centralised image library and archive
From regional to national: digital pathology network transformation
Transforming a regional digital pathology network into a national programme across the UK has the potential to save the NHS around £100m a year. Such a network – one that sees a centralised digital pathology image library and archive, as opposed to individual hospitals having their own infrastructure and teams to manage it – can also offer a range of other benefits alongside significant cost…
News • Promising reseach results
Using artificial DNA to kill cancer
Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way. The method showed promising results against various cancers in lab tests on mice.
Article • Image augmentation, interpretation and evaluation
AI in multimodality hybrid imaging: a diamond in the rough
AI-based models for multimodality hybrid imaging have the potential to be a potent clinical tool but are currently held back by a lack of transparency and maturity, says Dr Irène Buvat, from the Laboratory of translational Imaging in Oncology, Institute Curie in Paris, France.
News • Novel approach in pathology
Laser microbiopsy: a minimally invasive method to extract tissue samples
In a recent study, a US research team developed a revolutionary laser-based approach to perform microbiopsies. Their novel method could make biopsies faster, more cost-effective, and less harmful to the patient.
News • T cell visualization
Whole body scan shows complexity of immunotherapy response
Dutch scientists have performed whole-body PET scans using a radioactively labeled antibody tracer against immune cells, to predict the effect of treatment with immune checkpoint inhibitors.
News • High-sensitivity blood test
New cancer testing method to make regular monitoring affordable
Scientists from Singapore discovered a novel low-cost method of testing for cancers. The test sequences heated clinical samples to isolate cancer-specific signatures found in a patient’s blood.
News • Glioblastoma treatment approach
'Zapping' brain cancer cells shows surprising benefits
Canadian researchers have developed a new method of killing brain cancer cells while preserving the tissue around it. A remarkable side-benefit: chemotherapy of the cancer suddenly becomes possible.
Article • Cancer screening
The need for breast imaging for transgender patients
The need for breast cancer screening of transgender individuals has been a topic of uncertainty until recently, due to lack of reliable patient data, consensus by radiologists, published research, and recommended guidelines. A 2021 survey of Society of Breast Imaging (SBI) members revealed that ‘breast radiologists differ in their practice and knowledge regarding screening of transgender…
Article • Alternative to lumpectomy
Breast cryoablation for surgically inoperative patients
Breast cryoablation is an emerging treatment for early-stage, localized breast cancer that destroys malignant tumours by freezing them. During the past decade, it has been increasingly utilized as an alternative to lumpectomy, but its long-term benefits compared to other breast cancer treatments are still unproven.
Article • Regulatory challenges for AI-based diagnostics
Further IVDR changes: a step in the right direction, but…
New changes made to the timetable for the In vitro Diagnostic Medical Device Regulation (IVDR) across Europe could have a significant impact on manufacturers and users, an expert points out. While the extension of the transition period was a welcome step, other changes which were hoped for remain painfully absent.
Article • Digitisation in the OR
Robotic duo pushes boundaries of microsurgery
One robot supports the surgeon’s control of tiny instruments, while another automatically keeps an eye on what is happening: With this novel combination, surgeons in Münster have successfully performed fully robot-assisted microsurgery for the first time. Presenting the new procedure at the Hornheide Specialist Clinic, the experts explain how the interaction of both robotic systems ensures…
Article • Tissue-engineered glioblastoma model
3D brain tumour in a dish to personalize cancer treatment
It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.
Article • Visceral imaging
Endosonography: AI takes on the “supreme discipline”
Endosonography poses unique challenges for medical professionals, because two demanding disciplines have to be mastered at the same time. The use of artificial intelligence (AI) could help speed up the notoriously slow learning curve of the procedure, says Prof Dr Christoph F. Dietrich. At the Visceral Medicine Congress in Hamburg, the expert explained how AI can help endosonography achieve…
News • Tumor location as important growth factor
New molecular microscopy uncovers breast cancer spread
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease.
News • CLL types with distinct biological and clinical features
Whole genome profiling reveals new leukaemia subgroups
A collaborative study has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukaemia (CLL), and associated these with clinical outcomes.
News • Immune systems timulation
Using senescent cells as anti-cancer vaccines
Researchers from Barcelona report that vaccination with senescent cells shows promise in experimental models of melanoma and pancreatic cancer.
News • Possible biological explanation found
Why are dense breasts associated with increased cancer risk?
The risk of developing breast cancer is higher in breasts with high density. But why is that? Researchers at Linköping University have shown major biological differences that promote cancer growth.
Article • Detecting several different diseases
Multiplex diagnostics: next-generation techniques for new challenges
With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.
News • Focal therapy study
New prostate cancer treatment to reduce risk of impotence
Focal treatment of prostate cancer involves treating only the tumor and not the entire gland, sparing surrounding tissue and nerves. The method is being evaluated in a research study.
News • Filopodia research
'Sticky fingers' in cells keep breast cancer contained
Researchers in Finland have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumours.
News • Children’s cancer
Rhabdomyosarcoma: Blood tests could offer smarter treatment
A simple 'liquid biopsy' blood test could help guide the treatment of children with the cancer rhabdomyosarcoma, a new study reports.
Supervised learning approach
A new deep learning-based algorithm to predict relapse-free survival in papillary thyroid carcinoma
The tall cell variant (TCV) is an aggressive subtype of papillary thyroid carcinoma (PTC). Sebastian Stenman, researcher from the Institute for Molecular Medicine, and the Department of Pathology at the University of Helsinki, Finland, is developing and training a deep learning algorithm using supervised learning to detect and quantify the proportion of tall cells in PTC.
Malignant tumour management
’Our machine learning model achieved 88.9% accuracy in predicting the sarcoma-specific survival rate’
Clinical management of soft tissue sarcoma is particularly challenging. Dr Sebastian Foersch, researcher at the Institute of Pathology at the University Medical Center in Mainz, Germany, has used a deep learning model for diagnosis and prognosis prediction of soft tissue sarcoma using conventional histopathology slides.
Article • Patient care
Molecular Tumour Board for better decision-making
As more genomic alterations become targets for therapy, health institutions and hospitals are creating specialist Molecular Tumour Boards to support better decision-making for patient care. This evolving team, and its role, was highlighted in a presentation at the 34th European Congress of Pathology in Basel, Switzerland.
Article • AI provides prognostic information
Next-generation deep learning models predict cancer survival
Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…
News • New imaging method
Delayed fluorescence for effective surgical tumor removal
Researchers propose a new approach to identify cancerous tissue for surgical removal, based on real-time imaging of tissue oxygen concentration.
News • Model system shows tumor grwoth
Novel organoid model for pancreatic cancer
Researchers in Munich have developed a novel model system that can be used to precisely track the growth steps and three-dimensional arrangement of pancreatic cancer cells.
Sponsored • The 50 shades of brown
Sakura Finetek Europe enables optimal only Advanced Staining results
Imagine a new quality standard that improves the lives of patients and lab professionals in cancer care.
News • How cancer spreads
Cancer metastasis: Breakthrough to lead to better treatments
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
News • Drug delivery research
'Tunneling' capsule to enable oral insulin intake
A newly developed capsule that tunnels through mucus in the GI tract could be used to orally administer large protein drugs such as insulin.
News • Assessing bone quality via blood sampling
New device for diagnosing bone fragility
A new device for diagnosing bone fragility invented by the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE) has been approved for marketing in the European Economic Area and Switzerland. The device is based on a new approach to assessing bone quality via blood sampling.
News • Alveolar rhabdomyosarcoma
Promising new treatment for deadly pediatric tumor
Alveolar rhabdomyosarcoma is a rare pediatric tumor. For more than 40 years there has not been any new development regarding treatment. Research led by Prof. Dr. Anton Henssen at Charité University Berlin has now identified a new therapeutic option, using a drug that is currently under investigation for other types of cancer.
News • Lung adenocarcinoma
Therapeutic target against common lung cancer identified
A new study led by researchers in Barcelona has determined the protein TIMP-1 as a valuable biomarker for the progression of lung adenocarcinoma. The results open the door to new treatments.
Article • Interpreter of maladies
Will AI help realize the promise of precision medicine?
Machine learning and artificial intelligence (AI) have the potential to transform cancer treatment management worldwide. Their ability to rapidly analyse and integrate routinely acquired diverse data will improve the accuracy and effectiveness of precision medical treatments.
News • Precision oncology
What's new in cancer therapy?
Researchers from the University of Bern and Inselspital provide an overview of the latest technologies in precision oncology. Translating these into clinical application is still a major challenge.
News • Desperate cancer cells
How tumors mutate their way out of a crisis (and become drug-resistant)
Researchers discovered that cancer cells mobilize a SOS response when they are desperate to resist anticancer drugs. The team also came up with an anti-SOS approach that blocked the mechanism in mice.
Article • Modelling systems for human biology
Organoid technology: new opportunities for drug discovery
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
News • Relapse rate research
Breast cancer: Fertility preservation measures do not increase recurrence risk
A new study shows that women with a breast cancer diagnosis undergoing procedures for fertility preservation are not at increased risk of recurrence of the disease or disease-specific mortality.
News • Impact of body constitution
Breast cancer: Tumour environment can affect prognosis
The interplay between the patient’s BMI, tumour size and cancer-specific proteins is of importance for the prognosis of breast cancer, a study from Sweden shows.
News • AI vs. NSCLC
Streamlining lung cancer radiotherapy with Deep Learning
UK researchers developed and validated a deep learning algorithm that can identify and outline a non-small cell lung cancer (NSCLC) tumor on a CT scan within seconds.
News • High-glade glioma research
Understanding why deadly brain cancer comes back
A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.
Video • Clonal somatic mutations
How does cancer grow? Genetic mapping gives new insight
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
Article • Hologic at ECR 2022
Painting a global picture of Women’s health
At the ECR 2022 congress in Vienna, Hologic went beyond just showcasing new systems for women’s health. Additional focus topics were the mitigation of the pandemic impact on screening programmes and the situation of women around the world without access to advanced diagnostic technologies – or even the most basic standards of healthcare.
News • Diabetes
Device prevents buildup of scar tissue around implants
A new device, which doesn’t rely on immunosuppressing drugs, may assist efforts to develop an artificial pancreas to treat diabetes.
Article • Controversial compound
Seeking alternatives to gadolinium-based contrast agents
Researchers are seeking alternatives to gadolinium-based contrast agents (GBCAs) to help raise levels of patient safety. An open hybrid session at ECR in Vienna heard how research across several centres has been examining the options of new approaches to reduce reliance on GBCAs.
News • Determining aggressiveness
New discovery improves prostate cancer prognosis
Researchers in Sweden have now discovered a faster and easier way to determine who has an aggressive form of prostate cancer, and who has not.
News • Identification of treatment barriers
Immunotherapy: The right environment for fighting cancer
Cancer immunotherapy is a successful treatment form in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers found.
News • Radiophysiomics
Diagnosing brain tumors using machine learning
The classification of brain tumors—and thus the choice of optimal treatment options—can become more accurate and precise through the use of artificial intelligence in combination with physiological imaging.
News • Biomarker from blood test
Lung cancer: Liquid biopsy accurately predicts immunotherapy response
A simple blood test could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure.
News • World premiere
A liver was treated in a machine and successfully transplanted
The research team Liver4Life has treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.
News • Lung cancer
A novel AI for digital pathology analysis
Researchers from Boston University School of Medicine have developed a novel artificial intelligence algorithm to assess digital pathology data.
News • Oncology
A new biomarker for personalized breast cancer therapy
"Crown-like structures" surrounding breast tumors in overweight and obese patients could hinder their response to therapy. The findings of this study could potentially be used to improve personalized treatment for patients.
Article • Glioblastoma analysis
Revealing tell-tale signs of deadly brain cancer
A new way of differentiating healthy from diseased cells could pave the way for more personalised treatment for patients diagnosed with glioblastoma multiforme (GBM), a common and aggressive type of brain tumour.
Article • Detection and diagnosis of cancer
The ‘smart’ future of cytology
A combination of digital pathology and quantitative biomarker analysis in the emerging concept of ‘smart’ cytology has a potential role in the detection and diagnosis of cancer.
Article • NPIC network
Pathology in North England goes digital
Reaching out across 15 hospitals and a population of six million people, a network established by the National Pathology Imaging Co-operative (NPIC) is an ambitious move to advance digital pathology in the North of England.
News • Dermatology tool
Skin cancer detection: handheld device as painless alternative to biopsy
A new handheld device has been developed to painlessly identify skin cancers using millimeter-wave imaging. This could slash the rate of unnecessary biopsies.
News • Companion treatment
Magnetic therapy to enhance breast cancer chemotherapy
A team of researchers from Singapore has developed a novel magnetic therapy that serves as an effective companion therapy to chemotherapy to enhance treatment outcome for breast cancer.
News • Customized to the patient
Organ-on-a-chip systems go 'plug and play'
A major advance demonstrates first multi-organ chip made of engineered human tissues linked by vascular flow for improved modeling of systemic diseases like cancer.
News • Tumour plasticity
Why breast cancer metastases spread to the bone
A protein vital in determining the organs affected by metastasis has been identified by Swiss researchers. This could lead to the development of therapeutic approaches to suppress metastasis.
Article • Ovarian cancer and endometriosis detection
Women’s health imaging: PET/CT and T2*w MR show promise
Diagnostic imaging in women’s health advances: PET/CT might provide a more accurate imaging alternative to CT in ovarian cancer. T2*-weighted MR imaging in deep endometriosis detection also shows promise, but ultimately falls flat.
News • Histotripsy
Tumors partially destroyed with ultrasound don't come back
Noninvasive sound technology breaks down liver tumors in rats, kills cancer cells and spurs the immune system to prevent further spread.
Article • ECR Round table discussion
Specialists build bridges in interventional oncology
Delivering a drug directly inside a lesion using minimally invasive procedures opens up new perspectives for patients and medical teams. At ECR Overture, experts looked at how to best join forces to advance the field of interventional oncology.
News • No more biopsies?
3D microscope reveals features in living tissues
MediSCAPE, a high-speed 3D microscope, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments.
News • 'Sweet' assistance
3D printed vascular models to help cancer therapy
3D-printed sugar models of dense and chaotic blood vessel networks near tumors could help future cancer treatments.
News • Radiofrequency myth debunked
No, smartphones are not a driver of brain tumour risk (not even with 5G)
Can mobile phones increase the risk of brain cancer? A new, large study was unable to verify such concerns. However, the researchers say it might still be a good idea to cut back on smartphone time.
News • Oncology
A laser-powered upgrade to cancer treatment
A new research venture pairs cutting-edge particle accelerator science and radiation therapy.
News • Magnetic tentacle
A small robot to explore the lungs
A proof of concept for a robot that can reach some of the smallest bronchial tubes in the lungs to take tissue samples or deliver cancer therapy.
News • Cancer imaging
MRI 2.0 lights up cancerous tissue
Synthetic correlated diffusion makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.
News • AI-GUIDE system
Handheld robot can help stem fatal blood loss
The AI-Guided Ultrasound Intervention Device is a lifesaving technology that helps a range of users deliver complex medical interventions at the point of injury.
News • Mammogram analysis
AI accurately classifies breast density
A software based on deep learning with convolutional neural networks can accurately and consistently classify breast density on mammograms according to BI-RADS criteria.
Article • Cancer diagnostics
Bringing liquid profiling to the clinic
Liquid profiling is offering clear benefits in terms of cancer diagnostics and targeted therapy, but challenges remain in bringing it into the clinic.
News • Cancer proliferation
3D tumour model to unveil metastasis mechanism
Model tumour systems could help explain whether pressure differences can push cancer cells into their surroundings – a basic mechanism behind metastasis.
News • Inflammatory response
Drug coat on implants reduces "foreign body" reaction
An anti-inflammatory drug incorporated into the coating around an implantable electronic medical device – such as a pacemaker – can reduce the body’s "foreign body" reaction.
News • Cancer research
Origins of metastasis unraveled
For a long time, the origin of metastasis remained obscure. Now, scientists have discovered some of the mechanisms these cells arise.
Sponsored • Women's health
Improving Workflow and Patient Care Through Innovation
Groundbreaking technologies have improved our ability to accurately diagnose breast cancer and reduce callbacks, focusing on compassionate care for patients as they move along their breast health journey.
Sponsored • Integrated system
Accurate Real-Time Imaging Leads to Better Breast Biopsy Patient Experience
When it comes to your patient’s health, certainty matters. Breast biopsies play a vital role in the continuum of care for women, providing insights into mass and calcification identification so you can make the best-informed decisions.
News • New imaging approach
Diagnosing prostate cancer with ultrasound
UK researchers have found that a new type of ultrasound scan can diagnose most prostate cancer cases with good accuracy in a clinical trial involving 370 men.
News • Cancer research
Transparent ultrasound chip improves imaging
A biocompatible ultrasound transducer chip could be a more effective way to harness the technology for biomedical applications.
Article • Endoculus
Robotic ‘mini-tank’ to enhance colonoscopy techniques
A miniature colonoscopy robot on tank-like treads, which carries a camera and uses other small surgical tools, could have clear benefits for both patients and endoscopists.
News • Cancer therapy
Chemo after breast cancer surgery? Gene expression test to help decision
Physicists from Leipzig University have developed gene expression tests to examine whether additional chemotherapy is necessary and really effective after breast cancer surgery.
Sponsored • Orthopaedics
Periprosthetic joint infection: a complex issue
Periprosthetic joint infection (PJI) can be an enormous challenge for orthopaedists and trauma surgeons. Antibiotic-loaded bone cement is an important element in a prevention strategy.
News • Women's health
Breast and ovarian cancer risk assessment from cervical samples
Scientists have discovered a means of identifying the risk of breast and ovarian cancer by measuring epigenetic changes in cervical samples from over a thousand women.
News • Novel therapy approach
MRI-guided magnetic seeds to kill cancer with heat
Scientists at University College London have developed a novel cancer therapy that uses an MRI scanner to guide a magnetic seed through the brain to heat and destroy tumours.
Article • Regulatory issues for AI and digital pathology
IVDR: a complex issue and a 'missed opportunity'
Despite a five-year transition period for In-vitro Diagnostic Medical Device Regulation (IVDR), experts fear many actors in the field are still not prepared for the regulations coming into force.
News • Dermatology diagnostics
AI-powered app to speed up skin cancer diagnoses
A mobile application assists in recording skin lesions and sends them to dermatology departments in hospitals, speeding up diagnosis of skin cancer.
News • Brachytherapy side-effects
Countering skin damage from cancer radiation therapy with light
Light therapy may accelerate the healing of skin damage from radiation therapy by up to 50%, according to a recent University at Buffalo-led study.
News • Diagnostic
Potential therapeutic target for lung cancer
Scientists reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic target for lung cancer.
News • Glioblastoma
Blood test for brain tumors possible
Researchers at the University of Sussex are one step further to developing a blood test capable of diagnosing the most aggressive form of brain tumour.
News • Without causing neurological damage
Injections of zika virus destroys brain tumors
In both the mice and organoids, cytokines suppressed tumor growth after treatment, and defense cells migrated to the brain region affected by the tumor, alerting the immune system to its existence.
News • Multiple tumor tissue biomarkers
MOSAICA: next-generation biopsy technology
A new biopsy tool will enable scientists and clinicians to simultaneously profile many biomarkers in cells and tissues.
Article • Precision medicine
Liquid biopsy: the ‘next frontier’ for cancer detection?
Mark Nicholls reports from the National Cancer Research Institute (NCRI) virtual Festival, with four expert speakers discussing the role of liquid biopsy in cancer detection.
News • Adversarial attacks
Fake images can fool cancer-spotting AI and human experts
Artificial intelligence (AI) models that evaluate medical images have potential to speed up and improve accuracy of cancer diagnoses, but they may also be vulnerable to cyberattacks.
News • Synthetic tissue
Hydrogel material repairs vocal cords
Combining knowledge of chemistry, physics, biology, and engineering, scientists from McGill University develop a biomaterial tough enough to repair the heart, muscles, and vocal cords, representing a major advance in regenerative medicine.
News • New method
3D imaging to determine prostate cancer aggressiveness
A team led by the University of Washington has developed a new, non-destructive method that images entire 3D biopsies instead of a slice. The 3D images provided more information than a 2D image — specifically, details about the tree-like structure of the glands throughout the tissue.
Article • Key technologies
Artificial intelligence in medicine will prevail
Artificial intelligence (AI) is changing our healthcare systems. It can help us detect diseases earlier, improve patient care and reduce healthcare costs. However, there is still a lack of trust, of rules and safety regulations and of broad data pools. How can we use AI successfully in healthcare systems and what role will it play in the future?
News • Chemotherapy approach
New receptor insights might leave cancer bitter
Bitter taste receptors do not only support humans in tasting. They are also found on cancer cells. A team led by Veronika Somoza from the Faculty of Chemistry at the University of Vienna and the German Leibniz Institute for Food Systems Biology at the Technical University of Munich has investigated the role they play there. For this purpose, the scientists compiled and evaluated extensive…
News • Conducting diagnostics
Detecting breast cancer via electrical currents in the skin
Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation. While the risk of getting breast cancer is higher for older people, it can strike at any age. Studies show that 5% to 7% of females with breast cancer…
News • Osteoporosis
An ultra-thin 'computer on the bone'
Researchers have developed an ultra-thin wireless device, called osseosurface electronic, that grows to the surface of bone and could someday help physicians monitor bone health and healing over long periods.
News • Oncology
Tumor blood vessel a target to treat glioblastoma?
A novel protein regulator of tumor angiogenesis, TMEM230, was recently characterized by researchers to have a role in tumor development and vascularization, with potential as a target for anti-tumor therapy in difficult-to-treat cancers such as glioblastoma.
News • Lesions
'Virtual histology' may reduce need for skin biopsies
A 'new technology shows promise by analyzing images of suspicious-looking lesions and quickly producing a detailed, microscopic image of the skin, bypassing several standard steps typically used for diagnosis - including skin biopsy, tissue fixation, processing, sectioning and histochemical staining.
Article • Cancer research
Prostate cancer: Blood tests predict chemotherapy resistance
Researchers have found that regular blood tests can help detect whether prostate cancer patients have resistance to drugs treating the condition. The findings were presented at the National Cancer Research Institute (NCRI) virtual Festival.
News • Breast MRI study
IUDs have systemic effects on the body
Intrauterine contraceptive devices (IUDs) appear to have systemic effects on the body like those of hormone replacement therapy, according to a breast MRI study being presented at the annual meeting of the Radiological Society of North America (RSNA).
Article • Focused ultrasound
Histotripsy: fighting tumors with microbubbles
Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases. In this Medica-tradefair.com interview, Prof. Maciej Pech talks about testing cavitation events generated during histotripsy, explains the process, and reveals its advantages.
Article • Pre-, post- and interoperative
Wearable devices in the surgical environment
Wearable technology has become an important part of medicine, from tracking vital signs to disease diagnosis. In surgery, wearable technologies can now assist, augment, and provide a means of patient assessment before, during and after surgical procedures. Wearable technologies are applied before the patient even reaches the operating room, for example in prehabilitation, i.e. pre-treatment…
News • Coronavirus imaging
Brightest ever X-ray shows lung damage from Covid-19
The damage caused by Covid-19 to the lungs’ smallest blood vessels has been intricately captured using high-energy X-rays emitted by a special type of particle accelerator. Scientists used a new imaging technology called Hierarchical Phase-Contrast Tomography (HiP-CT), to scan donated human organs, including lungs from a Covid-19 donor.