Search for: "biomedical research" - 250 articles found

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Research Use Only

Shimadzu – MALDImini-1

Dimensions: 309 × 385 × 320 mm (w × d × h)Weight: 25 kgHighlights:With its simple configuration and compact size, it is possible to install the MALDImini-1 in places where mass analysis devices could not previously be used. Through ingenious engineering and innovation, its footprint has been reduced to the size of a piece of paper. The MALDImini-1, with its MS3…

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Article • AI is key

Lung cancer screening initiatives across Europe

Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.

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News • Low field imaging

0.05 Tesla MRI: When less is more

A whole-body MRI scanner with a compact 0.05 Tesla permanent magnet has been developed that operates on a standard wall power outlet without radiofrequency or magnetic shielding cages.

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Video • Imaging of speech disorder

MRI shows stuttering in real-time

What happens in the internal speech muscles when people are stuttering? Researchers now showed the mechanical aspects using real-time MRI. This could lead to better treatments of speech disorders.

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Article • Transformative technology

Generative AI in healthcare: More than a chatbot

‘Computer, why did the doctor take that MRI scan of my leg? And what did it show?’: Popularized by OpenAI’s ChatGPT, generative artificial intelligence (AI) is already beginning to see practical applications in medical settings. The technology holds immense potential, with benefits for patients, clinicians, and even hospital administration, according to Shez Partovi, MD.

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Article • Affordable and widely accessible

Robotics applied in support of patient wellbeing

Keeping technology simple and affordable is key in helping patients to fully benefit from robotic systems, according to a leading expert in the field. While expensive and complex systems have been developed, Professor Heike Vallery believes the full potential of robotics in patient care will only be realised when they become more affordable and widely accessible. She also underlines the…

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Article • Experts explore impact of technology

AI in radiology: helper or bane of society and the environment?

The climate crisis and AI – arguably two of the most hotly-debated and relevant topics of our time – share an intricate relationship: While computation of complex AI routines commands an immense carbon footprint, it is these algorithms that might be the very key to mitigate the effects of global warming. In a dedicated session at ECR 2023, radiologists explored the societal and environmental…

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News • Based on image-based flow cytometry

Rapid test to predict severe Covid-19 infections

Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…

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Article • Five-year EU project to avoid heart damage in oncology patients

Cardiac collaterals in breast cancer therapy

Modern cancer therapies are tough on the tumours, but often, also on the heart of the patients. The “CARDIOCARE” project aims to reduce the cardiac burden of anti-cancer therapies through more patient-tailored treatment approaches. At the ESC 2023 cardiology congress, Professor Katerina Naka from the project’s consortium explained why older patients are at the highest risk of cardiotoxic…

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Article • Sustainability

The challenge of "greening" medical technologies

Under the impulse of the European Commission, the in vitro diagnostic industry is developing emerging technologies to implement sustainable practices in medical laboratories. As sustainability has been a growing priority of the European Union (EU) in the last decade, ‘the medical technology sector, particularly the IVD sector, must comply with European legislation in this field like all other…

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Article • Experts outline European infrastructure

AI in health imaging: computational power isn’t everything

What will the future structure for artificial intelligence in health imaging across Europe look like? While the algorithms show great promise in collecting, storing, analysing, and using data to advance healthcare, delegates to a session on the topic at ECR 2023 in Vienna, also heard that it was important for the use of AI to move from research and more toward practical applications for patients.…

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Article • Tissue-engineered glioblastoma model

3D brain tumour in a dish to personalize cancer treatment

It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.

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Article • Alternative to open surgical procedures gains traction

The future of minimally invasive interventions

In the future, many types of open surgeries will be replaced with minimally invasive interventions, predicts Kevin Cleary, PhD, engineering lead at the Sheikh Zayed Institute for Pediatric Surgical Innovation at Children’s National Hospital, and Professor of Pediatrics and Radiology at George Washington University, both in Washington, D.C. Surgeons and interventional radiologists will be able…

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News • Nonfungible tokens

Can NFT technology benefit healthcare?

NFTs, or nonfungible tokens, first made a splash in the art world as a platform to buy and sell digital art backed by a digital contract. But could NFT be useful in other markets such as healthcare?

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Article • Benefits of multimodality imaging

Stroke: The importance of workflow

When a patient suffers a stroke, speed in treatment can mean the difference between successful recovery, permanent disability, or death. For Christopher Hess, success in stroke diagnosis is a question of workflow and efficient care delivery.

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Article • Super-resolution miscroscopy

PEAR: setting nano-imaging in motion

Ever since the Abbe diffraction limit of conventional microscopy has been surpassed, super-resolution techniques have been diving ever deeper into the most miniscule details of molecular structures. We spoke with Prof. Dominic Zerulla, whose company PEARlabs is developing an imaging technique that sets out to push the boundaries once more – by looking at in-vivo nano-scale processes in motion.

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Article • Bioprinting

3D biocomposites can repair large bone defects

Loosening hip implants can cause major damage to the bone and a simple replacement won’t suffice to carry the load during movements. “To solve this problem we have to turn to innovative technologies such as bioprinting. Scaffolds are required that – while adapting slowly – offer long-term stability,” says Professor Dr Dieter Wirtz, Director of the Department of Orthopaedics and Trauma…

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Article • Game elements

Gamification in diabetes care

The number of gamified mobile applications is rising rapidly—especially in healthcare. Gamified apps or devices are used in many fields, from mental health therapy to stroke rehab to managing metabolic conditions. This article illustrates how gamification is employed in diabetes care.

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Article • Diabetes

Microneedles: Nano-sized, huge impact

Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…

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Article • WSI, AI and more

New digital frontiers for nephrology

Digital technology solutions create new opportunities in diagnosis and assessment of renal conditions. With whole slide imaging (WSI), improved workflow and better visualization, such technology already yields a ROI for hospitals and laboratories.

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News • Coronary microcirculation

New measurements improve diagnosis of ‘woman’s heart’

Researchers at the Catharina Heart and Vascular Center, together with Eindhoven University of Technology, have developed a new measurement method to analyze the smallest capillaries of the heart by measuring blood flow and resistance. The new method to assess coronary microcirculation allows cardiologists to make a clearer diagnosis. Until recently, the tests used for this purpose were not…

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News • Multiple biomarker detection

Smart bandage shows promise for chronic wound monitoring

A research team led by Professor Lim Chwee Teck from the National University of Singapore’s (NUS) Department of Biomedical Engineering and Institute for Health Innovation & Technology (iHealthtech), in collaboration with clinical partners from Singapore General Hospital, has developed a smart wearable sensor that can conduct real-time, point-of-care assessment of chronic wounds wirelessly…

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Article • Pregnancy imaging

Machine learning predicts placenta health from MRI scans

Machine learning methods are being used to predict the health of the placenta from a 30-second MRI scan. Researchers hope the approach will offer an insight into the health of expectant mothers and unborn babies by detecting the early signs of dangerous conditions such as pre-eclampsia. Researchers from the School of Biomedical Engineering & Imaging Sciences at King’s College London (KCL)…

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News • DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…

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News • Resource management

Automated filling machine could stave off Covid-19 vaccine shortage

Researchers in Thailand have developed a device to get the most out of vaccine supplies: The automated vaccine filling machine from the Faculty of Engineering at Chulalongkorn University can fill AstraZeneca vaccine into syringes with precision, speed, and safety, helping to increase the number of vaccinated people by 20 percent. The prototype is now operating at Chula Vaccination Center and more…

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Article • Skin cancer identification

Dermatology & AI: The need to quantify skin tones

Although artificial intelligence (AI) tools and smartphone apps that help identify suspicious moles and potential skin cancers are starting to proliferate, dermatology informatics has far to go before becoming a clinically adoptable technology. Many challenges need to be resolved, not least of which is the need for more image data representing people of colour.

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Article • Immersive imaging distraction

VR system to reduce MRI scan anxiety

Claustrophobia or anxiety can overwhelm small children and people with cognitive difficulties, especially in a confining and noisy MRI scanner tube. Their restless reactions can then render scan images useless. To help such patients to relax during scanning, a team from King’s College London (KCL) has designed an immersive environment with a special virtual reality (VR) headset for use with MRI…

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News • Promising material

Organ transplantation: polymer coating reduces rejection rate

Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted. The polymer, developed by Prof. Dr. Jayachandran Kizhakkedathu and his team at the Centre for Blood Research and Life Sciences Institute at the University of British Columbia, substantially diminished rejection of transplants in mice when…

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News • Tool to identify tumour mutations

Machine learning fuels personalised cancer medicine

The Biomedical Genomics laboratory at the Institute for Research in Biomedicine (IRB) Barcelona has developed a computational tool that identifies cancer driver mutations for each tumour type. This and other developments produced by the same lab seek to accelerate cancer research and provide tools to help oncologists choose the best treatment for each patient. The study has been published in the…

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News • Coronavirus protein and antibody detection

Bioluminescence lights up traces of Covid-19 in the blood

Home test kits to check for Covid-19 spike proteins and anti-Covid-19 antibodies are fast and simple to use but lack the sensitivity and accuracy of laboratory tests. Researchers from Eindhoven University of Technology with Utrecht University have developed a new type of sensor that combines the sensitivity and accuracy of current laboratory-based measurements with the speed and low-cost of…

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News • Hydrogel framework

Synthetic tissue with growing blood vessels developed

Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain stable in the organism long enough for the body to form new natural structures. A fundamental requirement for functional tissue is that blood vessels must be able to grow in…

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News • Cardiology research

Dynamic heart model gives insight into cardiac disease progression

Efforts to understand cardiac disease progression and develop therapeutic tissues that can repair the human heart are just a few areas of focus for the Feinberg research group at Carnegie Mellon University. The group's latest dynamic model, created in partnership with collaborators in the Netherlands, mimics physiologic loads on engineering heart muscle tissues, yielding an unprecedented view of…

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Article • Screening, early detection, treatment optimisation

AI techniques advancing oncology care

Cancer care and the treatment clinicians can offer patients is being increasingly enhanced by Artificial Intelligence (AI). The technology has a role in diagnosis, with algorithms trained to design and deliver patient care, can match patients to clinical trials they may benefit from, and even help predict outcomes and those at greatest risk.

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News • Deep learning vs Aids

AI app could help diagnose HIV more accurately

Pioneering technology developed by University College London (UCL) and Africa Health Research Institute (AHRI) researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries. Academics from the London Centre for Nanotechnology at UCL and AHRI used deep learning (artificial intelligence/AI) algorithms to improve health workers’…

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News • Promising research tool

World's first digital cancer cell model

Computer models have been standard tools in basic biomedical research for many years. However, around 70 years after the first publication of an ion current model of a nerve cell by Hodgkin & Huxley in 1952, researchers at Graz University of Technology (TU Graz), in collaboration with the Medical University of Graz and the Memorial Sloan Kettering Cancer Center in New York, have finally…

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Article • Personalised medicine

'Body-on-a-chip' technology boosts drug development

Integrating laboratory functions on a microchip circuit is helping improve the cost-effectiveness of drug development. So-called ‘lab-on-a-chip’ or ‘human-on-a-chip’ technology can highlight which treatments may, or may not, work before advancing along the clinical trial process. It can also have benefits for chronic and rare diseases, as well as helping shape personalised medicine.…

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News • Cardiovascular disease prevention

An ultrasound sensor to measure pulse wave velocity and blood pressure

Nanoelectronics and digital technologies company Imec presents a proof-of-concept for determining arterial stiffness, a risk marker for cardiovascular diseases such as stroke and heart failure, and monitoring blood pressure. Imec’s approach uses an ultrasound sensor to measure the central pulse wave velocity. Measuring pulse wave velocity closer to the heart is also a more reliable proxy for…

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News • Transient implant

A pacemaker that dissolves when it's no longer needed

Researchers at Northwestern and George Washington (GW) universities have developed the first-ever transient pacemaker — a wireless, battery-free, fully implantable pacing device that disappears after it’s no longer needed. The thin, flexible, lightweight device could be used in patients who need temporary pacing after cardiac surgery or while waiting for a permanent pacemaker. All components…

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News • Digital patients, promising results

Are 'virtual' trials the future of research?

A study involving virtual rather than real patients was as effective in evaluating a medical device used  to treat brain aneurysms, according to new research. The findings are proof of concept for what are called in-silico trials, where instead of recruiting people to a real-life clinical trial, researchers build digital simulations of patient groups, loosely akin to the way virtual…

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Video • Handheld rapid testing

New tech to diagnose infections in minutes - without a lab

The idea of visiting the doctor’s office with symptoms of an illness and leaving with a scientifically confirmed diagnosis is much closer to reality because of new technology developed by researchers at McMaster University. Engineering, biochemistry and medical researchers from across campus have combined their skills to create a hand-held rapid test for bacterial infections that can produce…

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News • Sonothermogenetics

Tool activates deep brain neurons by combining ultrasound, genetics

Neurological disorders such as Parkinson’s disease and epilepsy have had some treatment success with deep brain stimulation, but those require surgical device implantation. A multidisciplinary team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely…

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News • Neuroscience

A deep dive into the brain

Researchers from ETH Zurich and University of Zurich have developed a new microscopy technique that lights up the brain with high resolution imagery. This allows neuroscientists to study brain functions and ailments more closely and non-​invasively.

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News • Combining common risk factors

Deep learning enables dual screening for cancer and CVD

Heart disease and cancer are the leading causes of death in the United States, and it’s increasingly understood that they share common risk factors, including tobacco use, diet, blood pressure, and obesity. Thus, a diagnostic tool that could screen for cardiovascular disease while a patient is already being screened for cancer has the potential to expedite a diagnosis, accelerate treatment, and…

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Article • Digital pathology

Today’s tissue for tomorrow’s research

Specialist biorepositories are helping advance personalised medicine by supporting the availability of human tissue for research using digital pathology techniques. The pivotal role of the Glasgow Tissue Research Facility (GTRF) in making tissue available to shape new therapies and treatments was outlined in a presentation to the online “Transforming Digital Pathology – Integrating AI to Move…

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News • Medication testing

'Airway-on-a-chip' to find new Covid-19 drugs

A collaboration spanning four research labs and hundreds of miles has used the organ-on-a-chip (Organ Chip) technology from the Wyss institute at Harvard Univesity to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes Covid-19. The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the…

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