An “out-of-this-world” project has the potential to transform the future of tissue engineering and liver transplantation through research conducted aboard the International Space Station (ISS).
Telesurgical procedures, new resection techniques, robot-assisted surgery: The sixth Semi-Live conference at University Hospital Heidelberg looked at how surgical approaches have evolved in the last few decades driven by technical advances in the ongoing quest for precision and excellence in patient care.
Not just a Nirvana song, but also an effective way to keep a donor heart fresh for transplantation: New research shows the benefits of “heart-in-a-box” storage.
New research into a life-threatening, but underestimated complication in lung transplants not only provides new insights, but also approaches for early detection and timely treatment.
Matching the right donor heart to the right recipient at the right time is a complex task. Now, experts point out how AI can provide unbiased decision-support for transplantation process.
Although robots are common to assist in surgery, robotic assistance is not routinely used for lung transplants. However, this might change soon, according to an expert speaking at the ISHLT meeting.
A team of Northwestern University scientists has developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn’s disease.
A special perfusion machine preserves donor livers for an extended period of time without compromising organ quality. New Dutch research has confirmed the safety of the procedure for recipients.
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
Experts presented state-of-the-art and emerging techniques to treat chest tumours and discussed common issues in the management of pneumothorax at RSNA 2022. Current ablation methods in the thorax include radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation (CRYO), irreversible electroporation (IRE) and pulsed electric field.
Photon-counting CT allows for a comprehensive, simultaneous evaluation of lung structure and function, something not possible with standard CT, according to a new study.
Using an organ from a donor who underwent cardiac death, Stanford Medicine surgeons transplanted a heart while it was beating - the first time such a procedure has been achieved.
Storing donor lungs for transplant at 10 degrees Celsius markedly increases the length of time the organ can live outside the body.
In a promising study, Canadian researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients.
One robot supports the surgeon’s control of tiny instruments, while another automatically keeps an eye on what is happening: With this novel combination, surgeons in Münster have successfully performed fully robot-assisted microsurgery for the first time. Presenting the new procedure at the Hornheide Specialist Clinic, the experts explain how the interaction of both robotic systems ensures…
Donor hearts from people who were Covid-19-positive appear to be as safe for transplantation as those from people without Covid-19, according to a new short-term analysis.
Despite treatment, chronic lung diseases such as COPD or cystic fibrosis can become so severe that a lung transplant is necessary. Dr Urte Sommerwerck explains which patients might be considered for transplantation and why follow-up is as important as the surgery itself.
Many consider our eyes to be the windows to the soul. Yet the cornea, the panes of these windows, sometimes need significant repair. Friso Heslinga, PhD, created artificial intelligence models to support surgeons in one of the oldest and most common transplantation procedures.
Researchers at Lund University in Sweden and Skåne University Hospital have conducted an animal study bringing hope that more donor lungs could be used in the future.
A new heart transplant technique, which allows surgeons to transplant donor hearts that have stopped beating after death, is reducing waiting lists for patients in Australia and potentially around the world.
An animal study brings hope that more donor lungs could be used in the future. The researchers have launched a pilot study to investigate whether the treatment will have the same positive effects on human beings.
Interventional cardiologists in Seattle recently performed a first-in-human procedure, successfully employing a catheter-delivered device to retrieve a benign tumor from inside a patient’s heart.
A research team has created the first gel-based cartilage substitute that is even stronger and more durable than the real thing, offering a promising solution for patient suffering from knee pain.
Researchers at McMaster University create device to replicate conditions in blood vessels after grafts.
Treating liver cancer tumours to shrink them in order to allow the patient to qualify for a liver transplant leads to excellent 10-year post-transplant outcomes, according to new research.
Using deep learning, researchers created AI-driven computer models to analyze corneal and retinal images to help eye doctors in the future.
The research team Liver4Life has treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.
MediSCAPE, a high-speed 3D microscope, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments.
A new study has proved that it is possible to convert blood type safely in donor organs intended for transplantation. This is an important step towards creating universal type O organs.
US surgeons perform historic first successful transplant of porcine heart into adult auman with end-stage heart disease.
Doctors in Lisbon report on the case of a 61-year-old man who received a double lung transplant after his lungs were irreparably damaged by Covid-19.
Wearable technology has become an important part of medicine, from tracking vital signs to disease diagnosis. In surgery, wearable technologies can now assist, augment, and provide a means of patient assessment before, during and after surgical procedures. Wearable technologies are applied before the patient even reaches the operating room, for example in prehabilitation, i.e. pre-treatment…
The first investigational transplantation of a genetically engineered, nonhuman kidney to a human body was recently completed at NYU Langone Health—marking a major step forward in potentially utilizing an alternative supply of organs for people facing life-threatening disease.
After a liver transplant, patients have to take immune-suppressing drugs for the rest of their lives. These so-called immunosuppressants prevent the organ from being rejected. However, the drugs increase the risk of cancer and serious infections. They can also significantly impair kidney function and even lead to dialysis. In order to be able to give those affected as much immunosuppression as…
Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappeared completely, researchers at the University of Zurich (UZH) and University Hospital Zurich (USZ) have found. Their findings will now be tested in…
Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted. The polymer, developed by Prof. Dr. Jayachandran Kizhakkedathu and his team at the Centre for Blood Research and Life Sciences Institute at the University of British Columbia, substantially diminished rejection of transplants in mice when…
With the first-in-man implantation of the Berlin Heart Venous Cannula at the LMU University Hospital Munich, Germany, Berlin Heart offers patients with a failing Fontan circulation a unique chance to survive the waiting time for a donor heart. These patients are in a life-threatening condition: their health has deteriorated so much that they desperately need a new heart, but because of their poor…
A potential new treatment to protect immunosuppressed patients from human cytomegalovirus (HCMV) has been discovered by scientists at the University of Cambridge. Their study shows that certain epigenetic inhibitors expose and help to destroy dormant HCMV infections, which often reactivate to cause serious illness and death in these vulnerable groups. Subject to clinical trials, their proposed…
Scientists have used a technique to grow bile duct organoids – often referred to as ‘mini-organs’ – in the lab and shown that these can be used to repair damaged human livers. This is the first time that the technique has been used on human organs. The research paves the way for cell therapies to treat liver disease – in other words, growing ‘mini-bile ducts’ in the lab as…
Italian neurosurgeon Professor Francesco Di Meco, explored the current and potential role of intra-operative ultrasound in neurosurgical oncology during the annual meeting of the European Association of Neurosurgical Societies (EANS) this October. The extent of resection is considered a prognostic factor in operative neuro oncology surgery and image-guided surgery is being regarded as one of the…
Siemens Healthineers AG took a big step last October. To incorporate treatment along an entire clinical path, the firm acquired Corindus Vascular Robotics, Inc., to combine image-guided diagnosis with robot-assisted surgery. A couple of months later, the Corindus endovascular robotic system CorPath GRX was used to implant a vascular stent into an obstructed coronary artery – the first use of…
The sunny Sunday of March 22, 2020, may well go down as a watershed date in the context of Coronavirus in the UK. A couple of days earlier, UK schools had closed en masse – open only thereafter for children of key workers – and the British government had advised that pubs, bars, cinemas, gyms and restaurants should close and people should adhere more rigorously to social distancing.
An organic compound produced by the gut flora – the metabolite 4-Cresol – is considered to have protective effects against both type 1 and 2 diabetes, notably by stimulating the growth of the insulin-producing pancreatic beta cells. This is according to a new study led by Inserm researcher Dominique Gauguier at the Environmental Toxicology, Therapeutic Targets, Cell Signaling and Biomarkers…
A team of researchers from Osaka University, Kyoto Prefectural University of Medicine, and Toppan Printing Co., Ltd. succeeded in reconstructing adipose tissue balls (“mini-breasts”) with a functional vascular network using patient-derived cells, achieving a high graft survival rate in small animal models. So far, silicone breast implants were primarily used in breast reconstruction following…
The British Heart Foundation (BHF) announced its shortlist of four research projects competing for a single £30 million award. The charity says it is one of many radical new approaches needed to address a frightening mismatch in research funding compared with the burden of heart and circulatory diseases. With the World Health Organization forecasting an increase in cardiovascular deaths…
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week. This breakthrough may increase the number of available organs for transplantation, saving many lives of patients with severe liver diseases or cancer. Until now, livers could be stored…
Unlike other surgical specialties, ear nose and throat (ENT) has been poorly served by the introduction of robotic platforms to enhance procedures. Since the da Vinci system first gained FDA approval in 2000, robot-assisted surgery has become commonplace in many specialties, including neurology, urology, etc. with numerous other general surgical applications. However, existing systems including…
Our eyes – considered by many to be the windows to the soul – need constant care, and as we age, they sometimes also need significant repair. The panes of these windows – the corneas – are transparent tissues that have been the focus of some of the oldest and most common transplantation surgeries. Now thanks to researchers in Kyoto, some such transplants may become even safer. The team,…
For patients with Type 1 diabetes who don’t respond well to insulin or have other serious medical complications caused by their disease, pancreas transplantation offers hope for a cure. But obese candidates who need a pancreas transplant often are denied the procedure because of poor outcomes, including high rates of incision infections, which are linked to an increased risk for failure and…
The safety of blood transfusions is questioned again and again by the mass media. Sometimes ‘bad’ blood causes infections; sometimes a transfusion leads to cancer years later. The fact is that transfer blood is subjected to the highest safety standards – there are very clear statutory regulations. Nonetheless, there will be shortages of ‘life’s fluid’ because, given increasing…
The consequences of organ rejection in transplant patients can be devastating. Professor A. Vathsala, co-director of the National University Centre for Organ Transplantation at the National University Hospital (NUH) and professor of medicine, says that between 30 percent to 40 percent of kidney transplants are lost over time to rejection. She and Associate Professor Paul MacAry of the Department…
Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients. A clinical trial conducted in collaboration with researchers at Karolinska Institutet in Sweden now shows that a new drug…
Many methods to treat current or chronic wounds are available. However, the differences in general conditions prevailing in hospital, or for out-patient care, make effective therapy more difficult. Each patient also has other preconditions for healing. Improved communication between everyone involved in the treatment would benefit patients. We see a lot of progress with the issue of “wounds”,…
A new device developed by Stanford University researchers could make it easier for doctors to monitor the success of blood vessel surgery. The sensor, detailed in a paper published in Nature Biomedical Engineering, monitors the flow of blood through an artery. It is biodegradable, battery-free and wireless, so it is compact and doesn’t need to be removed and it can warn a patient’s doctor if…
‘Do we want transplant medicine? And if yes, what are we prepared to change in public policy, society and medicine?’ This question characterises the current situation within this medical discipline. Since the 2011 transplant scandal, there has been a steady decline in organ donations according to the German Foundation for Organ Donation (DSO). Although there were some 1,200 transplant donors…
The CRISPR genome editing technique promises to be a "transformative leap" in genetic engineering and therapy, affecting almost every area of medicine. That includes plastic surgery, with potential advances ranging from prevention of craniofacial malformations, to therapeutic skin grafts, to new types of rejection-free transplants, according to a paper in the November issue of Plastic…
Cell stress in combination with an altered microbiota in the colon drives tumour growth. Previously, it was assumed that this combination only contributes to inflammatory intestinal diseases.
Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, PhD, collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage. Their findings appear in Nature…
Weak, easily broken bones are an epidemic in the United States. They’re often tied to osteoporosis, a disease that causes bones to degenerate over time. This makes them less flexible, more brittle, and easier to break. According to the International Osteoporosis Foundation, more than 44 million Americans aged 50 and older either have or face the threat of developing osteoporosis due to low bone…
Hygiene is still a leading topic in endoscopy, and education remains crucial in Europe, according to Ulrike Beilenhoff, scientific secretary of the European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA). The two subjects took centre stage during the 21st ESGENA Conference, held during UEG Week in Barcelona this October. With around 600 participants, lectures, posters,…
Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I study is part of a multi-center collaboration dedicated to employing innovative therapies to improve outcomes for children…
Donating blood is a tangible way to help people who are struggling with serious health conditions, yet many people may not think about it or make time for it. In January – which the American Red Cross has dubbed National Blood Donor Month – blood bank supplies are typically among the lowest of the year, as many people have been traveling or busy with the holidays. Inclement weather can also…
When researchers examined information on pairs of kidneys from the same donor in which 1 kidney was used but the other was discarded, the kidneys that were used tended to perform well even though they were similar in quality to their partner kidneys that were not used. The findings from a study provide further evidence that many of the donated kidneys that are discarded are in fact suitable for…
A team of researchers led by the University of Minnesota has 3D printed lifelike artificial organ models that mimic the exact anatomical structure, mechanical properties, and look and feel of real organs. These patient-specific organ models, which include integrated soft sensors, can be used for practice surgeries to improve surgical outcomes in thousands of patients worldwide. “We are…
Liver disease is widespread in Germany. It is, in fact, the most common cause of death in patients under the age of 40, with liver cirrhosis, which can develop into liver cancer, playing a major role here. These days, modern, comprehensive treatment concepts are unimaginable without interventional radiology, for liver cirrhosis as well as liver cancer. Prof. Dr. Christian Stroszczynski, Director…
In a spectacular development, Spanish researchers demonstrate for the first time that 3-D printing can be used to produce human skin deemed appropriate for transplants and testing applications.
With a scarcity of lungs available for transplantation, the use of lungs from donors older than age 60 has been shown to achieve reasonable outcomes and should be considered as a viable option, according to research published online in The Annals of Thoracic Surgery. “The availability of suitable donor lungs for transplantation continues to be a major obstacle to increasing the number of lung…
Point-of-care ultrasound is a valuable tool for successful dialysis fistula surgery, allowing pre-operative mapping to find a suitable site and post-operative fistula scanning to check for stenosis and adequate blood flow. Anna Jerram, a clinical vascular scientist at the Manchester Royal Infirmary, discusses the role POC ultrasound played during a recent trip to the Gambia to provide critical…
21st century challenges are multitudinous for all. Ageing populations, a changing disease burden; increasing obesity with associated morbidities – Type 2 diabetes, cancer and cardiovascular disease; climate change pressures and more. Any new build plan demands a low carbon footprint; respect for the environment is paramount. To capture all those elements, the plan to regenerate a previously 10…
Surgeons at Johns Hopkins Medicine report that their first series of a minimally invasive procedure to treat chronic pancreas disease, known as severe pancreatitis, resulted in shorter hospital stays, less need for opioids and fewer complications, compared with standard surgical approaches.
Language recognition on the smartphone, spam filters in the e-mail programme, personalised product recommendations by Amazon or Netflix – all share one feature: they are based on an algorithm that recognises patterns in a set of data. This artificial generation of knowledge is called machine learning.
'Blood is a very special juice’ – something even Goethe’s Mephistopheles knew. Medics have also known this for centuries, so it’s nothing new that the ‘juice’ and its properties receive a lot of attention in medicine. However, what is new is that dealing with the use of blood through patient blood management (PBM) is coming to the fore.
A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.
Repeated infection with the bacterium Clostridium difficile (C. difficile), which causes stomach upsets and diarrhoea, is linked to higher death rates, as well as having a significant impact on health services in terms of cost and hospital beds occupied. This issue will be adressed in two presentations at the 27th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID),…
Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient’s immune system attacks, or “rejects,” the donated organ.
Riad Salem, MD, MBA, will be honored with the Society of Interventional Radiology (SIR) Foundation Leaders in Innovation Award March 7, during the group's annual scientific meeting in Washington, D.C., for his work in radioembolization.
First thing on a recent Monday morning, Professor Tomasz Grodzki could be found performing a lung resection in an operating theatre at the Regional Hospital for Lung Diseases in Szczecin-Zdunowo. Just two days earlier he was in a meeting with Senator John McCain, in Washington D.C.
At the 2nd International Conference on 3D Printing in Medicine from May 19-20, 2017 in Mainz, Germany, the focus is on innovative deployment options for the 3D print process in medicine. Today already, 3D printing is being applied in virtually all medical disciplines.
A new method which doubles the usual time donor lungs can remain outside the body can benefit patients, staff and allow retrieval of donor lungs across greater geographical areas, says a study published in The Lancet Respiratory Medicine.
In rare cases, a dangerous bacterial infection occurs following major cardiac surgery. A device which is used for the regulation of body temperature has been found to be responsible for this. Since this discovery was made, Bern University Hospital has been working on guidelines for infection prevention.
Since lung diseases tend to be complex, imaging is a crucial diagnostic tool. While computed tomography has become the standard modality, which is frequently used outside hospital settings, specialised MRI diagnostics remains the preserve of large university medical centres.
Surgery will change – with all the challenges that developments such as Big Data create there are no two ways about it. However, how deep those changes run remains to be seen. In a rather young field of research, scientists look at the ways all components used during surgery can be interlinked. Professor Beat Müller, co-initiator of the project ‘Cognition-Guided Surgery’, explains results…
21st century technology has outpaced our expectations. One such example is the invention of advanced digital manufacturing techniques, better known as 3-D printing. Patients and the medical community are yet to see the full implementation of this technology within healthcare.
Mechanical ventilation and subspecialisation are key aspects of modern anaesthesia and critical care practice according to Dr Javier Garcia Fernandez, Head of Critical Care and Anaesthesiology at University Hospital Puerta de Hierro in Madrid.
A Northwestern University research team has developed a 3D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic “bone” material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.
Using the results from a computerized mathematical model, Johns Hopkins researchers investigated whether they could improve heart and lung transplantation procedures by transferring patients from low-volume to high-volume transplant centers.
‘Amputation v. reconstruction’ – a vital issue – was debated by two leading surgeons during the Microsurgical Lower Limb Reconstruction session at the Advances and Controversies in Reconstructive Microsurgery (ACRM) 2016 conference, held in the United Kingdom this May. Consultant Plastic Surgeon Umraz Khan, from North Bristol NHS Trust presented a plastic surgeon’s view, while Ben…
A small report in the press prompted examination of a much neglected topic. The report read ‘Heart Centre at University Hospital no longer carries out transplants’, and referred to the University Hospital Frankfurt, one of the 22 Heart Centres that perform these transplantations.
Embracing robotic technology in the realms of microsurgery will have significant benefits for patients, clinicians and hospitals. Leading hand and peripheral nerve specialist Professor Philippe Liverneaux believes using robots will not only enhance patient outcomes and improve cosmetic appearance but also bring significant cost benefits to health systems.
Robot-assisted surgery still meets with considerable skepticism even though Intuitive Surgical’s Da Vinci system has been around for more than a decade. However, few surgeons and researchers are seeking ways to expand the surgical toolbox. Not so the members of the working group ‘Surgical technology and training’ at the General, Visceral and Transplantation Surgery Department, University…
Coronary or peripheral bypasses are the most frequently performed vascular operations. Although one million patients per year and around the world, undergo this intervention, its failure rate reaches 50%, because of poor vessel healing, leading to vessel graft occlusion. To improve the outcome of bypasses, researchers from the University of Geneva (UNIGE) work together with medical doctors from…
MedUni Vienna researchers have published the results of a clarifying research study on the potential transmissibility of Alzheimer’s disease. Although the protein associated with Alzheimer’s disease, amyloid-β, might be transmissible under very unusual circumstances, this does not go along with a transmission of the clinical manifestation of Alzheimer’s disease. The affected persons…
Scar-free facial reconstruction is now a reality. A team led by Daniel Borsuk, a doctor at Hôpital Maisonneuve-Rosemont and a professor at the University of Montreal, recently conducted the very first such procedure in the history of plastic surgery in Canada.
Astellas Pharma EMEA today announced that it will host the Antimicrobial Resistance in Europe: Innovating Today to Protect our Health Tomorrow debate at the Bibliothèque Solvay, Brussels, on 3rd December, 2015. The event will convene leading scientists and economists from across Europe to discuss how policy-level innovation can address antimicrobial resistance (AMR) – the single greatest…
With 3-D printing revolutionising manufacturing, its healthcare potential is being explored for medical devices, prosthetics, dentistry and drug development. One area under the spotlight is the creation of artificial muscles using a 3-D printing system. Dr Fergal Coulter, who has played an important role in helping develop the technique, outlined the manufacturing process, which he invented for…
‘It’s like a new lease on life,’ says Wolfgang R, ‘I can feel the difference between grass and concrete again.’ Eight years ago the Austrian teacher‘s lower leg had to be amputated following thrombosis. Today, he is the first leg amputee, worldwide, to sport a sensory-enhanced prosthesis. ‘For the wearer the prosthesis is not a numb object, but a part of the body,’ says Dr Hubert…
A new 3D computer modeling system may significantly improve a surgeon's ability to select the best sized donor heart for children receiving heart transplants, according to research presented at the American Heart Association's Scientific Sessions 2015.
Surgeons at The Children’s Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world’s first bilateral hand transplant on a child. Earlier this month, the surgical team successfully transplanted donor hands and forearms onto eight-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney…
When a patient receives a new hip, it is usually adjusted only approximately to leg length. Greater accuracy requires a more precise measuring process as well as adjustable implants. Now, a new type of measurement method coupled with a modular implant should allow orthopedic surgeons to precisely calibrate leg length after the operation so it matches its original length.
Surgeons at the University Hospitals Leuven have used a new technique for two recent liver transplants: in both cases the organ was preserved prior transplantation in a device that mimics the environment of that in the human body, making sure the liver stays ‘healthier’. The device can even assess and improve the quality of the liver.
Publicly insured Americans who undergo lung transplantation for cystic fibrosis fare markedly worse in the long run than both publicly insured patients in the United Kingdom and privately insured Americans, according to the results of a study conducted by researchers from Johns Hopkins in Baltimore and U.K. colleagues working in that nation’s government-funded National Health Service.
Blood transfusions are avital part of medical care and yet the subject raises questions. ‘Blood transfusion should be restricted’, according to Professor Anders Perner, from the Institute for Clinical Medicine, Rigshospitalet, Copenhagen. ‘Blood transfusion could be more liberal’, says Dr Yasser Sakr, Senior Physician at University Hospital Jena. Debating their opposing views at the ISCEM…
Ask about UltraFast ultrasound and you might expect a technical answer explaining why the ultrasound is faster. However, for Stéphanie Franchi-Abella MD, fast means just fast, an ultra-quick acquisition she can take of a squirming, agitated new-born in the blink of an eye. ‘These babies are small and breathing rapidly, the organs are moving fast in the image and it’s sometimes difficult to…
The very first successful organ donation from a newborn to be carried out in the UK is reported in the Fetal & Neonatal Edition of Archives of Disease in Childhood. The donor was a girl born at term after an emergency caesarean section in the neonatal unit of Hammersmith Hospital, London. The donation involved the kidneys, which were transplanted into a patient with renal failure, and liver…
Researchers are using computed tomography (CT) and 3-D printing technology to recreate life-size models of patients' heads to assist in face transplantation surgery.
Another patient in the final stages of heart failure has received an artificial heart at Nantes UniversityHospital Centre, according to Carmat, the manufacturer of the device. Report: John Brosky
Could the widely predicted shortage of qualified staff in German hospitals soon lead to tough competition for members of Generation Y, ultimately resulting in a change in hospital structures and a revolution in the country’s total healthcare system? Perhaps. EH spoke with Professor Christian Schmidt, Medical Director and Head of the Board at Rostock University Hospital, and with consultant…
Donor transplant rejection and cancer relapse have two things in common: early recognition is vital and monitoring is hugely challenged.
The University Medical Center in Utrecht (UMCU), The Netherlands, is in the process of creating a multidisciplinary centre of excellence, able to manage resources efficiently while delivering the highest level of patient care and clinical research.
A recent study from the Heidelberg-based company Sciomics, a spin-off from scientists from the German Cancer Research Center (DKFZ), has presented an advanced method to predict the recurrence of bladder cancer after surgery. The method, which can help avoid frequent cystoscopy examinations in a majority of patients, is based on an analysis of the protein composition of cancer tissue obtained…
In a series of studies involving 140 American men and women with liver tumors, researchers at Johns Hopkins have used specialized 3-D MRI scans to precisely measure living and dying tumor tissue to quickly show whether highly toxic chemotherapy – delivered directly through a tumor’s blood supply – is working.
The first patient to receive a totally implantable artificial heart died 75 days after the procedure. The cause of death on March 2, 2014 was not disclosed in a short announcement made by the Hôpital Georges-Pompidou in Paris. European Hospital reported on his new heart device in the recently published issue 1/2014.
The number of patients treated with implants – from cardiac pacemakers, heart valves and vascular implants to artificial hips and knees – is rising worldwide.
Since minimally invasive surgery (MIS) entered cardiac surgery in the mid-1990s it became unthinkable not to use this medical specialty. However, MIS procedures do not always result in the best outcome for patients.
In France, every year 15,000 women undergo complete or partial mastectomy due to breast cancer. Only about a third of them, i.e. around 5,000 patients, use the possibilities reconstructive surgery offers and 70 percent of those women opt for an implant although it is associated with a risk of infection because the body might react negatively to the foreign object.
Professor Axel Haverich and team at the Clinic for Cardiothoracic, Transplant and Vascular Surgery in Hanover Medical School (MHH) have been carrying out research into decellularised heart valves for over 15 years. They trialled a procedure – initially in the laboratory and in animal experiments – which does not cause tissue rejection, is hoped to last a lifetime and, in the case of children,…
The C-Pulse, manufactured by Australian-American company Sunshine Heart, Inc. is neither a pulsatile artificial heart nor one of the well-known non-pulsatile left heart support systems
The 2013 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy¹ developed in collaboration with the European Heart Rhythm Association (EHRA), have created a new classification system for bradyarrhythmias according to mechanisms rather than aetiology.
A social media push boosted the number of people who registered themselves as organ donors 21-fold in a single day, Johns Hopkins researchers found, suggesting social media might be an effective tool to address the stubborn organ shortage in the United States.
CARMAT, the designer and developer of the world’s most advanced project of total artificial heart, announces today that it has obtained the approval of four renowned international cardiac surgery centers in Belgium, Poland, Saudi Arabia and Slovenia to proceed with the first clinical implantations of its bioprosthetic total artificial heart.
Simultaneous surgical successes open new perspectives for multiple transplants
Can an anaesthetist treat a patient with heart failure (HF) without any specialist knowledge of cardiology? That was the question posed by Dr Florian Weis, from the Clinic of Anaesthesiology at the University Hospital of the Ludwig Maximilian University Munich, when lecturing on perioperative management of this patient group.
A record number of liver transplants have been carried out by the Birmingham Liver Teams at Queen Elizabeth Hospital Birmingham and Birmingham Children’s Hospital.
‘Mass spectrometry has developed into a successful routine procedure,’ according to Dr Christoph Seger (Univ. Doz.), technical head of the Mass Spectrometry and Chromatography division at the Central Institute of Medical and Chemical Laboratory Diagnostics, Innsbruck University Hospital, Austria.
The 24th International Symposium of the AACC Critical & Point of Care Testing Division. Report: Michael Reiter
Artificial hearts, originally designed to bridge the time on the waiting list for a heart transplant, in recent years have increasingly become an independent treatment option for patients with chronic heart failure (HF).
The Danish inventor of an aortic valve for transcatheter implantation (TAVI) gains recognition for his achievement by colleagues within the European Society of Cardiology
Although scientists and medics have sought ways to grow artificial skin in laboratories since the 1970s, only now has it become possible to reproduce the top layer of skin, thanks to work at the Trauma Surgery and Orthopaedics Clinic in Berlin (ukb).
4,500 scientists, transplant teams and related social groups from 94 countries gathered in Berlin for the International Congress of the Transplant Society.
The worldwide scarcity of organ donations inevitably draws attention to the so-called Spanish model.
Are surgeons still opting for surgical procedures solely for medical need – or are economics forcing their decisions? That vexatious question, posed at the 129th Congress of the German, was spurned at the outset by Markus W Büchler MD, President of the Society and Medical Director of the Department of General, Visceral and Transplant Surgery at University Hospital Heidelberg. ‘We surgeons…
Meeting with EH editor Brigitte Dinkloh, Congress Secretary Professor Alexis Ulrich MD (left), Assistant Medical Director at the Clinic for General, Visceral and Transplant Surgery at the University of Heidelberg, outlined the scientific programme, discussed some impressive advances in surgical procedures, and explained why the gathering bears the slogan Surgery in Partnership.
Obesity is physically debilitating – and costly for healthcare. Losing excess weight has positive effects on the entire metabolism and improves life expectancy. However, for patients who cannot lose their morbid, excess weight through diet, today’s surgical interventions can help towards permanent weight loss – and reduction in insulin dependency for diabetics.
Johns Hopkins surgeons have established a facial transplantation team and are in the process of obtaining approval from the University’s Institutional Review Board (IRB) of their protocol to perform the complicated procedure.
Cardiovascular surgeon Dr Miodrag Todorovic explains how an island hospital – which is a medical centre of excellence and regional reference centre – is further improving medical care for patients there and in six neighbouring states with the help of a new picture archiving system from Visus
People who donate a portion of their livers for transplant to a relative or friend whose liver is failing can generally expect to live long, healthy lives and recover safely from the donation surgery, Johns Hopkins researchers have found.
Changing the organ donation process in this country from opt-in — by, say, checking a box on a driver’s license application— to opt-out, which presumes someone’s willingness to donate after death unless they explicitly object while alive, would not be likely to increase the donation rate in the United States, new Johns Hopkins research suggests.
By combining conventional medical imaging with some of the same 3-D modeling techniques used in Hollywood blockbusters, researchers are offering new hope to victims of serious facial injuries. Results of a new study on human face transplantation, led by Darren M. Smith, M.D., plastic surgery resident at the University of Pittsburgh Medical Center (UPMC), were presented today at the annual meeting…
Located in Vatican City in the heart of Rome, the Ospedale Pediatrico Bambino Gesù not only profits from a literally blessed base but also from an advanced IT-infrastructure in the radiology department. For over a year and a half, the largest children’s hospital in Italy has worked with the Carestream PACS, connecting the institution with two cooperating sites, one in Palidoro, one in St.…
Recent events have again underlined the reason why Papworth Hospital in ambridgeshire, England, maintains a enowned international reputation for cardiac and thoracic procedures. As Britains largest specialist cardiothoracic hospitals, over 2,000 major heart operations were performed there in 2010. In the year ending 1 April 2011, 824 patients had coronary bypass operations, including urgent,…
Although the 17 lectures delivered at this year‘s Medical Technology Congress in Berlin, Germany, focused on topics ranging from experimental and clinical research to routine daily diagnostic methods, the pervading interest was in the improvement, development and distribution of non-invasive imaging devices and corresponding software.
Bypass surgery figures declined again in 2010. Reason: Most coronary heart disease (CHD) patients are being treated by removal of the obstruction followed by stent implantation -- a situation criticised by Professor Jochen Cremer, first Vice President of the DGTHG (German Society for Thoracic and Cardiovascular Surgery).
Initially meant to bridge the gap before a heart transplant is performed, today ventricular assist devices (VADs) are increasingly considered ‘a lasting therapy option’, according to Professor Heinrich Schima, Head of the Centre for Medical Physics and Biomedical Technology at the Medical University of Vienna.
Morbid obesity is a chronic, lifelong, multifactorial, constitutional disease with negative medical, psychological, physical, social and economic side-effects. Obesity-related secondary diseases are Type 2 diabetes mellitus (T2DM), cardiovascular diseases such as hypertension or sleep apnoea. Report: Holger Zorn
Edwards Lifesciences Corporation, a global leader in the science of heart valves and hemodynamic monitoring, announced that interim data from a multi-center European prospective study of the investigational EDWARDS INTUITY Valve System showed promising results for patients undergoing surgical aortic valve replacement (AVR).
From first lady of breast MRI to the Germany’s most influential woman in radiology – that’s one way to describe Professor Christiane Kuhl’s switch from being Vice-Chairman of the Department of Radiology and Vice President of the University of Bonn to become Chairman of the Department of Diagnostic and Interventional Radiology at the University Hospital Aachen (UKA).
Emerging interventional techniques appear promising for the treatment of hepatic tumours, even those at advanced stages. Attendees at the special focus session on transarterial procedures, taking place today at ECR, will find out just how far these techniques, as well as combined approaches, have gone.
Vienna - For the 23rd time, the European Congress of Radiology (ECR) is opening its doors to welcome 19,000 participants from over 90 countries. The scientific exchange of knowledge and the presentation of the latest developments in the field of radiology will again be presented right in the heart of Europea. In an inaugural press conference on March 3rd, the hot topics of the congress were…
A statement by Jochen Franke, CEO of Philips Healthcare Germany, Austria and Switzerlandand, Head of the Advisory Council at MEDICA 2010.
Surgeon Alain Carpentier is ready to remove a patient’s heart and replace it with a mechanical device he spent 15 years developing. By 2013 the procedure will be performed on 50 European patients as part of a clinical trial to win CE approval for the world’s first fully implantable artificial heart.
The normal regulation of the core body temperature of a healthy, resting adult human (around 37°C) is affected during surgery, which can lead to an increased rate of wound infections, bleeding and cardiac complications. The manufacturer of MoeckWarming System reusable blankets reports that these provide comprehensive temperature management to ensure patients remain normothermic.
Neurosurgery has seen enormous progress, which should benefit as many patients as possible. However, according to Prof. Hanno Millesi MD, director of the Millesi Centre for Surgery of Peripheral Nerves, Wiener PrivatKlinik (WPK), a private hospital in Vienna, Austria, ‘methods are perceived incorrectly, because they are often confused with problematic predecessors, and sensible methods are…
Everyone (even if only marginally interested in public affairs) must have noted the current astronomic, worldwide public debts -- including the USA’s astounding $12 trillion. Additionally, everyone probably noted that, in many cases, this had something to do with the healthcare sectors.
In the current economic environment the introduction of novel imaging approaches and their reimbursement by payers is becoming increasingly difficult. Historically, this denotes a significant change, in that many currently accepted routine tests or interventions were accepted based on common sense, convincing experience or rapid adoption into clinical routine without much scrutiny.
Prior to the imaging workshop , Meike Lerner asked programme organiser, Professor Thomas M Deserno (Dept. of Medical Informatics, RWTH) about current developments today and how they affect future input from imaging manufacturers.
Innovate Indoor Air Quality (IAQ) is a conceptual and operational development. It is comprehensive, modern and multifaceted, to understand the risks and find solutions for indoor air. It goes beyond the sick building concept to define healthy environments and beyond the idea of indoor air being the only contaminant source.
When we organised the first Diagnostic Week in Karlsruhe, in 1969, no one could have known that this event would one day turn into the annual highlight in the world of medicine, reflected Dr Wolfgang Albath, laboratory medicine pioneer and one of the founding fathers of MEDICA the world`s largest medical trade show. Initially planned as a moving exhibition, the show has been based in…
A pioneering new treatment to repair leaking heart valves is being performed at a UK hospital as part of a clinical research trial. The minimally-invasive procedure to treat mitral regurgitation involves surgeons passing a device through a vein in the neck and into a patient's heart.
British girl Hannah Clark who was given an extra heart as a toddler has become the world's first heart transplant patient to make a full recovery after having her donor organ removed and function restored to her original heart. The case highlights that in some cases of cardiomyopathy, it is possible for the patient's own heart to make a full recovery if it is given adequate support to do so.
A rapid rise in 'altruistic donations', i.e. strangers having a kidney removed for an unknown patient, has been reported by the UK's Human Tissue Authority (HTA). Although there have been just 15 stranger donations (three still await surgery),
The technology firm NCR Corporation, which specialises in automated teller machines, self-checkouts and other self- and assisted-service solutions, announced in April that King's College Hospital NHS Foundation Trust in London has chosen to install the firm's new patient automated arrival system NCR MediKiosk. This autumn, 50 MediKiosks will be deployed in the dermatology, haematology,…
There is a profound difference between the complexity of cosmetic surgery or organ transplant procedures, for example, and other operations. Whilst procedures such as hair transplants or eyelid surgery present an alteration to the owner's body composition and changes to the patient's outlook, those changes were desired and planned for, in the hope that something marvellous will result and so…
Testing people for heart disease might be just a finger prick away thanks to a new credit card-sized device created by a team of researchers from Harvard and Northeastern universities in Boston.
Last year a special cardiac surgery department was opened in the Filatov Children's Hospital in Moscow. Until then, the only one in all of Russia was at the Children's Hospital #1, in Saint-Petersburg, where cardiac surgeon Vadim Lubomudrov has led the field in this delicate work.
As part of a global Safe Surgery Saves Lives programme, a simple, short checklist of guidelines for safe surgical procedures developed by the World Alliance for Patient Safety of World Health Organization (WHO) has produced dramatic results in the first eight hospitals that tested it.
In the sixth in his series for European Hospital, Professor Stefan Schönberg (left) of the Institute of Clinical Radiology and Nuclear Medicine (IKRN), University Hospital Mannheim, Medical Faculty of Mannheim, University of Heidelberg, invited colleagues from Mannheim and Vienna for a round-table discussion on:
Specialists at the Imperial College Healthcare NHS Trust, in London, have started using pioneering laser surgery to treat patients with pathological eye conditions, such as superficial corneal scarring.
We will use the grasping reflex - one of the first reflexes a baby utilises - without thinking for the rest of our lives. However, for those who suffer spinal cord injury of the cervical region, the upper extremities are affected along with the ability to grasp.
NeuroNexus Technologies and Philips Research announced that they have signed a joint research agreement to develop next-generation deep brain stimulation devices with the ambition to improve the treatment of neurological diseases and psychiatric disorders.
In October, the office of the Federal President announced that Professor Haverich, with his Hanover research team, has been nominated for the 'German Future Prize' for the development and successful use of adaptable biological heart valves
Tumour ablation - and Radiofrequency (RF) ablation in particular - is getting more and more important in oncology. The therapy option offers benefits in terms of costs, ease of set-up and flexibility so that experts see the need to expand the applications of it.
Joint replacemtents are daily hospital routine. A first national study in England gives information about the outcome of the often performed hip resurfacing and unicondylar knee replacement techniques. Both surgical operations try to preserve bone - but are they medically sensible?
Stefan G Ruehm, Kambiz Nael, Derek Lohan and Henrik J Michaely* describe impressive images that benefit patient treatment
Tumour cells can migrate, sometimes also during a surgery to remove the tumour. US researchers recently found, that perioperative treatment with a drug known as colchicine might protect against recurrences at the site of the surgical wound.
An interdisciplinary researcher team from the University of Sheffield has developed an ultra-fine, 3-dimensional scaffold to regenerate skin for wound healing. It dissolves after integrating in the wound and might provide a more safer way of treating injuries.
Reseacher from the Univerisity of Zürich discovered a new function of the “happiness hormone”, serotonin. It boosts the growing of colon cancer by enhancing the vascular development of tumors.
A meeting with Dr Valerij Mitish was difficult to arrange - every day he's at a different Moscow hospital.
Following 12 years of development, German surgeons and technicians have successfully implanted the world's first vision prosthesis in six blind patients.
Only few imaging modalities lend themselves to imaging of the lungs. Conventional chest radiography is the most commonly used tool in the investigation of pulmonary pathology but yields the perhaps most difficult, plain radiographs to interpret.
The Czech Republic's first cardiac transplant took place in 1984; now about 40 take place annually. The country's first lung transplants began ten years ago; to date around a hundred have been performed by Professor Pavel Pafko and colleagues at the Motol Faculty Hospital, in Prague.
Arrythmogenic remodelling of the left atrium is a common complication of atrial fibrillation, leading to severe haemodynamic disturbances.
In the heart of Paris, the Necker children's hospital, the oldest in the world dedicated to paediatrics, was suffocating inside a completely inward-looking enclave. The challenge was to achieve a vast upheaval to overcome the hospital's lack of relationship with its surroundings and open it onto the city, while also carrying out an in-depth metamorphosis to adapt it to new requirements.
Lifebridge is the first portable heart-lung machine which promises a great success for the clinlical use.
The new £2 million remote access stereotaxis catheter laboratory at London's Heart Hospital, funded by the British Heart Foundation (BHF), is the first of its kind in the UK and one of only 40 worldwide.
The Glide Solid Dose Injector (SDI), the needle-free drug delivery system that injects drugs in solid dosage form into the skin, has contributed to its manufacturer, Glide Pharma, winning the Best Business Award at the 2007 Medical Futures Innovation Awards.
By Kaj Blomqvist MSc (E.E.), electronic engineer for the Hospital District of Helsinki and Uusimaa (HUS), and currently in charge of the `Picis CareSuite Project´, which aims to automate all HUS acute care departments.
Already in 1993, the world market for contrast media was thought to be worth $ 3 billion. In 2001, an astonishing 12.2 million contrast medium-supported CT studies were carried out in Europe alone. Currently, the overall sales of contrast media are estimated to rise to $ 915 million in Europe in 2008.
The new European Transplantation Regulation makes it very difficult, or even impossible, to run a bone bank from 2007 onwards.
New pulsatile heart pumps (ventricular assist devices - VAD) can remain in the body as a permanent heart support.
The ethics committee of the UK' s National Health Service (NHS) has cleared the way for the world's first full face transplant.
According to leading transplant specialists, within five years almost all renal transplants will be steroid free.
Until now, a liver transplant was the only treatment for patients with liver failure. Now primitive cells might become an alternative therapy.
Nurse-surgeon training in the UK is lively discussed for other European countries doing the same to address their lack of qualified surgeons.
By Professor Gustav Steinhoff MD, director of the Department for Cardiac Surgery, and Christof Stamm MD, co-ordinator of clinical studies, at Rostock University, Germany
UK - Ten years ago a donor heart was transplanted into a 2-year-old patient, suffering cardiomyopathy, to take over the function of her own enlarged and failing heart. However, unlike many transplant cases - her own heart was not removed.
The European Society for Organ Transplantation (ESOT) - Europe's leading transplant society - has called for the universal backing of new schemes to safely and ethically increase donor organ numbers.
Ventricular assist devices (VAD) have been used since the 1980s, primarily to provide support after cardiac surgery for several days during recovery, or more often to keep patients alive until later heart transplantation (HTx).
Cardiac assist devices (CAD) are blood pumps that support the circulatory functions of severely ill cardiac patients.
Implants presently in use consist of a smooth or textured silicone shell filled with a silicone gel or saline solution. The latter has one decisive drawback - the breast may cool considerably in winter. Smooth silicone implants may also shift or turn.
The planning of hepatic surgery of primary and secondary liver tumours is a multimodal process, using modern imaging techniques - mainly contrast enhanced imaging such as CAT and MRI - depending on the patients individual situation as well as on the experience of the medical personnel who are planning the therapy.
The Austrian Society for Surgery and associated societies will focus on oncology/MIS,