In a new study, researchers show that the emergence of antibiotic resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.
To reduce the radiation exposure for patients undergoing frequent CT scans for pneumonia diagnosis, deep learning-based denoising of ultra-low dose CT presents a viable alternative.
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
The current rise in antibiotic resistance is once again sparking interest in phage therapy. Now, scientists developed a new tool that recommends the best possible phage cocktail for a given patient.
When an AI advisor points out an area of concern in a chest X-ray, radiologists are sometimes all too eager to follow their lead, a new study finds. This may lead to incorrect diagnostic decisions.
Wastewater treatment fails to kill several human pathogens, such as Listeria or E. coli, when they hide out on microplastics in the water, according to a new study.
Infections caused by antibiotic-resistant (AMR) bacteria are a major issue in hospitals. A new technique aims to effectively track all types of relevant microorganisms simultaneously.
Klebsiella is among the top three pathogens responsible for hospital-acquired infections (HAIs). Now, researchers discovered why the bacteria thrive in clinical environments.
Integrating bacterial genomic data with detailed human mobility data makes it possible to see how pathogens causing pneumonia and meningitis, move between regions and evolve over time.
Researchers have succeeded in developing “pathoblockers” that provide protection against the most common pneumonia-inducing pathogens, even if they are resistant to antibiotics.
Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.
Popular medications like Ozempic and Wegovy that are used to treat diabetes and obesity are associated with an increased risk of aspiration pneumonia following endoscopy, a new study finds.
An ageing population and modern lifestyle conditions have greatly increased the case numbers for hip arthroplasty. To prevent complications, it is important for orthopaedic surgeons to identify high-risk patients and take proper precautions. At the Heraeus symposium at DKOU, two experts explored the special measures that should be taken to ensure better outcomes for elderly and frail patients.
Once a patient’s body has been colonized by resistant bacteria, they can persist for a long time, a new study by the University and University Hospital of Basel shows.
Instead of killing viruses and bacteria with chemical disinfection, a new approach uses minuscule spikes to skewer them. This could be used to prevent surface contamination in hospitals or labs.
A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
Reports of AI gaining the upper hand in diagnostic imaging interpretation are piling up, but there are still areas where the eye of a trained human radiologist remains superior.
A research team led by the Institute for Bioengineering of Catalonia (IBEC) and Hospital del Mar has conducted a study to analyze cough sounds recorded by smartphones in patients with Covid-19.
Researchers from the University of Chicago developed a deep-learning model to assess chest X-ray radiographs for probable Covid-19 severity.
A family physician at Tufts University School of Medicine offers advice for how to treat allergies and how to tell if symptoms are due to allergies, the common cold, the flu, or Covid-19.
While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.
Under the impulse of the European Commission, the in vitro diagnostic industry is developing emerging technologies to implement sustainable practices in medical laboratories. As sustainability has been a growing priority of the European Union (EU) in the last decade, ‘the medical technology sector, particularly the IVD sector, must comply with European legislation in this field like all other…
Doctors across all disciplines, with assistance from artificial intelligence, may soon have the ability to quickly consult a patient's entire medical file against the backdrop of all medical health care data and every published piece of medical literature online.
Researchers have developed an inhalable powder that could protect lungs and airways from invasion from the coronavirus or flu viruses by reinforcing the body’s own mucosal layer.
Some hospitalized patients’ infections may develop from their own bacteria, new research results suggest. The study in mice indicates that medical interventions can awaken dormant, hidden bacteria.
A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.
Routine sampling of water supplies and genomic sequencing of Legionella bacteria could play a key role in identifying the source of Legionnaires’ disease outbreaks, research suggests.
Antibiotic prescribing in primary care could be monitored using health insurance data. And reduced with a simple test.
A new study could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae, which cause meningitis, are resistant to antibiotics.
A comprehensive assessment of scientific literature has uncovered empirical evidence that more than 58% of human diseases caused by pathogens, such as dengue, hepatitis, pneumonia, malaria, Zika, have been aggravated by climatic hazards.
Researchers developed an AI that accurately and quickly diagnoses idiopathic pulmonary fibrosis, based only on information from lung images and medical information collected during daily medical care.
Indwelling catheters through the urethra often cause bacterial infections. A newly discovered synthetic peptide is a promising treatment option, even against antibiotic-resistant pathogens.
Cambridge University Hospitals and the Faculty of Education are helping to bring medical training using 'mixed reality' technology a step closer.
Physicians use AI-powered technology for faster and earlier detection of diseases. At ECR Overture, Dr Steven Schalekamp, PhD, discussed the application of AI for chest radiography in paediatrics.
Scientists at the La Jolla Institute for Immunology discover new drug target for severe asthma and fibrosis.
The COVID-19 testing device can detect coronavirus infection in as little as 30 seconds as sensitively and accurately as a PCR test.
The long-term impact of the coronavirus pandemic on antimicrobial resistance remains difficult to predict. Infectious diseases consultant Professor Alison Holmes reflects on Covid-19's effect on antibiotic use in hospitals and beyond.
Doctors in Lisbon report on the case of a 61-year-old man who received a double lung transplant after his lungs were irreparably damaged by Covid-19.
To counteract the spread of resistant germs, researchers have developed new drug candidates that are able to render one of the most important hospital germs harmless.
Considerable advances in point-of-care testing (POCT) devices are emerging from lab-on-a-chip platforms, innovations in smartphone-based technology and wearable technology. Cloud-based deep learning systems herald a future revolution.
The damage caused by Covid-19 to the lungs’ smallest blood vessels has been intricately captured using high-energy X-rays emitted by a special type of particle accelerator. Scientists used a new imaging technology called Hierarchical Phase-Contrast Tomography (HiP-CT), to scan donated human organs, including lungs from a Covid-19 donor.
Researchers at the Centre for Genomic Regulation (CRG) and Pulmobiotics S.L have created the first ‘living medicine’ to treat antibiotic-resistant bacteria growing on the surfaces of medical implants. The researchers created the treatment by removing a common bacteria’s ability to cause disease and repurposing it to attack harmful microbes instead.
The impact of the coronavirus pandemic on lung cancer patient care across Europe, and the contribution lung pathologists, have led to a better understanding of Covid-19, as outlined during the 33rd European Congress of Pathology, Within ‘The lung pathologist in the Covid-19 pandemic’ session, speakers detailed how the pandemic has affected patients, diagnosis and clinical trials, yet also…
Covid-19 infection does not appear to affect the lung function of young adults, according to new research presented at the ‘virtual’ European Respiratory Society International Congress. In the first study to investigate the impact of Covid-19 infection on lung function, researchers led by Dr Ida Mogensen, a post-doctoral fellow at the Karolinska Institute, Stockholm, Sweden, found that even…
Unsupervised deep learning breaks new ground by predicting the progression of COVID-19 and survival of patients directly from their chest CT images.
Covid-19 disease severity is determined by the individual patient’s immune response. The precise mechanisms taking place inside the lungs and blood during the early phase of the disease, however, remain unclear. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität Berlin have now studied the cellular mechanisms…
A collaboration spanning four research labs and hundreds of miles has used the organ-on-a-chip (Organ Chip) technology from the Wyss institute at Harvard Univesity to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes Covid-19. The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the…
Research has identified critical factors that enable dangerous bacteria to spread disease by surviving on surfaces in hospitals and kitchens. The study into the mechanisms which enable the opportunistic human pathogen Pseudomonas aeruginosa to survive on surfaces, could lead to new ways of targeting harmful bacteria. To survive outside their host, pathogenic bacteria must withstand various…
Coronavirus researchers under Prof. Rolf Hilgenfeld of the University of Lübeck and Dr. Albrecht von Brunn of the Ludwig-Maximilians University of Munich discovered how SARS viruses enhance the production of viral proteins in infected cells, so that many new copies of the virus can be generated. Other coronaviruses apart from SARS-CoV and SARS-CoV-2 do not use this mechanism, thereby providing a…
The world is still failing to develop desperately needed antibacterial treatments, despite growing awareness of the urgent threat of antibiotic resistance, according to a new report by the World Health Organization. WHO reveals that none of the 43 antibiotics that are currently in clinical development sufficiently address the problem of drug resistance in the world’s most dangerous bacteria.…
Researchers have developed an innovative method to disrupt the formation of biofilms and thus facilitate the treatment of infections with Pseudomonas aeruginosa.
The results of a large-scale study indicate that the introduction of an AI-powered solution by healthcare software company Radlogics into radiology workflow to analyze Chest-CT scans during the Covid-19 pandemic reduced report turnaround time by an average of 30 percent, which is equivalent to 7 minutes per case.
Digital Covid-19 ‘symptom checkers’ may stop some patients from getting prompt treatment for serious illness, suggests an international case simulation study. Both the US and UK symptom checkers consistently failed to identify the symptoms of severe Covid-19, bacterial pneumonia, and sepsis, frequently advising these cases to stay home, the findings indicate. The availability and use of…
Improving workflow is one of the major challenges that radiology departments face. The need to be more efficient, deliver timely and effective patient care, and keep an eye on costs are all factors that seem to be ever-present in the modern imaging department. With the added demands of the coronavirus pandemic as radiology departments continue to play a critical role in the fight against…
Beta-glucan tests are proving to be pivotal in the better detection and diagnosis of fungal infections. As a robust complimentary test for traditional testing techniques and biomarkers, it is helping clinicians deliver rapid results and offering greater reassurance in more accurately identifying such infections. β-glucan testing, which is an in vitro diagnostic test, is regularly used at…
Healing the body with cells – this is the ambitious goal of scientists at Hannover Medical School (MHH). With this in mind, Professor Dr. Nico Lachmann and Dr. Robert Zweigerdt have initiated a research collaboration and license agreement with the pharmaceutical company Novo Nordisk A/S, to combine academic knowhow with the translational power of the industry. The overall aim of the endeavor is…
According to current studies, the Covid-19 disease which is caused by the SARS-CoV-2 coronavirus comprises at least five different variants. These differ in how the immune system responds to the infection. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, together with other experts from Germany, Greece and the Netherlands, present these findings…
Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body’s immune system within the first few days of the illness. But in a study published in Nature, investigators at Northwestern Medicine show Covid-19 pneumonia is…
The variety and volume of bacteria in the gut, known as the microbiome, may influence the severity of Covid-19 as well as the magnitude of the immune system response to the infection, suggests research published online in the journal Gut. Imbalances in the make-up of the microbiome may also be implicated in persisting inflammatory symptoms, dubbed ‘long Covid’, the findings suggest. Covid-19…
A panel of experts from the USA and China highlighted AI use in radiological workflow during the Covid pandemic and identified current pitfalls during the Hot Topic session at RSNA 2020. Radiologists from the USA prioritised Covid articles, delivered quick reviews, made all results open access, and helped organise a white paper from the Fleischner Society recognising recommendations for the role…
RSNA 2020: International experts showcased new studies on chest CT’s role in Covid-19 diagnosis and treatment. A staggering volume of work and has been produced on the pandemic this year, with an average 367 Covid-19 journal articles published per week, according to Michael Chung, Assistant professor of radiology at Icahn School of Medicine at Mount Sinai, NYC.
Professor Omolola Mojisola Atalabi, head of the radiology department and pediatric radiology unit at the University College Hospital Ibadan, Nigeria, will receive the Honorary Membership from the Radiological Society of North America (RSNA) during the society’s annual meeting. In an exclusive interview, she told HiE how she hopes this award will reflect on her younger peers and how she copes…
‘Mini-lungs’ grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs. Writing in the journal Cell Stem Cell, the researchers detail the mechanisms underlying SARS-CoV-2 infection and the early innate immune response in the lungs.
More than 32,000 people from over 160 countries registered for The Alzheimer’s Association International Conference (AAIC 2020) in July. This largest and most influential international conference on dementia science had to be held virtually this year, when important highlights were aired. The ability to identify individuals at high risk of developing Alzheimer’s Disease (AD), or at early…
A recent preprint study in France underpins the debate on whether lung ultrasound (LUS) should be used to triage COVID-19 patients better at the hospital as well as in primary care. The eChoVid study, published as a preliminary report of work on medTrix, shows that LUS enables identification of lung lesions as well as chest CT in COVID-19 patients. A team of French researchers compared routinely…
There are many reasons why for some patients a visit to the doctor’s office is difficult or well-nigh impossible – limited mobility after surgery, old age, or a handicap. For others, particularly in rural areas, the doctor is often far away and/or difficult to reach due to poor public transport. In times of corona, another important issue emerged: infection protection.
An easy-to-use score for predicting risk of death in adult patients admitted to hospital with covid-19 outperforms existing scores and can be used to support treatment decisions, finds a study published by The BMJ today.
Researchers at the University of Sheffield have developed a new compound that is able to kill both gram-positive and gram-negative antibiotic-resistant bacteria.
Fujitsu and Tokyo Shinagawa Hospital today announced the launch of a joint R&D project for AI technology to support diagnostic imaging via chest CT (Computed Tomography), which represents a promising candidate for the effective diagnosis of COVID-19 pneumonia.
Researchers at the University of Notre Dame are developing a new technique using artificial intelligence (AI) that would improve CT screening to more quickly identify patients with the coronavirus. The new technique will reduce the burden on the radiologists tasked with screening each image. Testing challenges have led to an influx of patients hospitalized with COVID-19 requiring CT scans which…
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.
Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction – rather, the immune response is caught in a continuous loop of activation and inhibition.
There are major complications from COVID-19 – ARDS, pulmonary embolism and neurological – that imaging can help detect, manage and/or follow up in the long term, radiologists from France and the UK explained during a recent ESR Connect session. ARDS is the most dreaded complication and the number one morbidity in COVID-19 patients. The incidence was up to 30% of patients in initial reports.…
Which patient will develop a severe form of COVID-19? This is an essential question which must be answered in order to improve the individual management and the prognosis of these patients. In a publication in the journal Science, teams from the Assistance publique – Hôpitaux de Paris (AP-HP), Inserm, Université de Paris, Institut Pasteur and Institut Imagine describe a unique and unexpected…
The coronavirus crisis has accelerated the use of telemedicine in Spain with an increase in virtual consultation and positive impact on workflow. The challenge will be to make these changes permanent, according to a panel of experts who took part in a conference last June in Barcelona. Spanish patients and healthcare professionals have widely accepted virtual consultation as a new alternative to…
MRI imaging is one of the best ways of examining different body tissue and obtaining information about injuries and illnesses. However, MRI scanners are typically large, heavy, and very expensive devices that need to be operated by specially trained healthcare personnel. Aalto University has just launched a project that studies and builds new magnetic resonance imaging technology, which enables…
The novel Coronavirus infection (severe acute respiratory syndrome SARS-CoV-2), which has led to the spread of COVID-19 around the world, has upset normal workflow in hospitals. The increased workload and stress, due to the necessity of implementing safe and separate diagnostic pathways, and the need to constantly monitor the development of the disease after its onset, continues to have a…
Royal Philips has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market a wide range of its ultrasound solutions for the management of COVID-19-related lung and cardiac complications.
Establishing whether a patient is suffering from severe lung disease, possibly COVID-19, within a few minutes: this is possible using fairly simple ultrasound machines that are enhanced with artificial intelligence. A research team at Eindhoven University of Technology (TU/e) and the University of Trento in Italy has been able to translate the expertise of top lung specialists into a software…
Although the clinical symptoms of new pediatric lung disorders such as severe acute respiratory syndrome (SARS), swine-origin influenza A (H1N1), Middle East respiratory syndrome (MERS), e-cigarette or vaping product use-associated lung injury (EVALI), and coronavirus disease (COVID-19) pneumonia may be nonspecific, some characteristic imaging findings "have emerged or are currently…
As the coronavirus spreads and infections with Covid-19 further increase throughout Europe, ECMO therapy turns out to be a necessary option for patients with severe courses. Xenios AG provides ECMO consoles that can be used for the treatment of patients who develop severe pneumonia and ARDS with lung failure which also might result from infection with the coronavirus.
Coronavirus can be identified automatically from sick patients’ lung X-rays using artificial intelligence (AI) developed at Brunel University London.
Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells. The identification of these cells by researchers from the Wellcome Sanger Institute, University Medical Centre Groningen,…
Scientists at the University of Cambridge have found an association between living in an area of England with high levels of air pollution and the severity of COVID-19, the disease caused by the SARS-CoV-2 virus. Because of the urgent need to share information relating to the pandemic, the researchers have published their report on MedRXiv. It has not yet been peer-reviewed. However, the…
Radiology experts from Norway and Germany highlighted the role of structured reporting in communicating clear results to the rest of the team, to improve patient and staff safety during the pandemic. They also related Germany’s experience of the crisis and what lies ahead in an online conference organized by the European Society of Radiology (ESR) last week.
As radiologists worldwide continue to share their knowledge of COVID-19 to help fight the pandemic, two chest experts from France and Spain talked about their country perspectives and the practical experience at their hospital in a dedicated online session organized by the European Society of Radiology (ESR).
People who are at high risk of developing lung cancer, such as heavy smokers, are routinely screened with computed tomography (CT), which can detect tumors in the lungs. However, this test has an extremely high rate of false positives, as it also picks up benign nodules in the lungs. Researchers at the Massachussetts Institute of Technology (MIT) have now developed a new approach to early…
Radiology, pathology, medical genetics and laboratory medicine under one roof: many hospitals are toying with the idea of ‘integrated diagnostics’ but it was the medical management at Geneva’s University Hospital that dared to take the first step and consolidate all these diagnostic disciplines in a single organisational unit: The Diagnostic Department. ‘Our long-term vision is a…
A coronavirus app coupled with machine intelligence will soon enable an individual to get an at-home risk assessment based on how they feel and where they’ve been in about a minute, and direct those deemed at risk to the nearest definitive testing facility, investigators say. It will also help provide local and public health officials with real time information on emerging demographics of those…
The current outbreak of the novel coronavirus disease (COVID-19) is making headlines by the minute. However, some less-than-trustworthy advice can be found among the information. Understandably, many people are concerned and confused. To prevent unnecessary panic, the World Health Organisation (WHO) has assembled advice for the public. Is it safe to receive parcels from China? Will sesame oil…
WHO Chief Adhanom Ghebreyesus has declared the novel coronavirus (SARS-CoV-2) a global health emergency. He said the decision was reached not because of the situation in China, but because of, “what is happening in other countries.” On Feb. 17, the number of infections totaled around 71,000 globally based on data of the WHO. COVID-19 – the official shorthand name of the novel corona virus…
Infrared thermometers are now used in most subway stations in China to prevent the spread of novel coronavirus (SARS-CoV-2) pneumonia (MCP). Many stations have implemented an artificial intelligence (AI) based fever screening system developed by the Beijing-based company Megvii Technology Limited. The system supports non-contact remote temperature screening from a distance of 3 meters. "This…
Research into the novel Wuhan seafood market pneumonia virus, the deadly "coronavirus" that has forced the Chinese government to quarantine more than 50 million people in the country's dense industrial heartland, will be facilitated by the UC Santa Cruz Genomics Institute. The Genomics Institute's Genome Browser team has posted the complete biomolecular code of the virus for researchers…
The novel coronavirus that recently originated in Wuhan, China has grabbed headlines and caused concern among public health officials around the world. Two infectious disease experts share their insights on the novel coronavirus epidemic.
Twice as many people as previously believed are dying of sepsis worldwide, according to an analysis published in The Lancet and announced at the Critical Care Reviews annual meeting in Belfast. Among them are a disproportionately high number of children in poor areas.
A probiotic drink could become a promising new weapon in the battle against antibiotic resistant bacteria, after a team of scientists at the University of Birmingham engineered and patented a key genetic element that can tackle the genetic basis of resistance. The team is now seeking funding for a clinical trial for the drink which has potential to work against many resistant bacteria commonly…
Nosocomial infections cause more deaths than traffic accidents – a stunning discovery made in a recent German study. Worse: infectious diseases long thought eradicated in Europe, such as measles, tuberculosis (TB) and, more recently, syphilis, are also implicated. The increasing number of patients places an additional financial burden on healthcare. But – and this might be the good news –…
PHE’s latest English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) report shows that there were an estimated 61,000 antibiotic resistant infections in England during 2018, a 9 percent rise from 2017.[i]
Spanish researchers in Valencia have identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. Presenting the research at the European Respiratory Society International Congress, Dr Francisco Sanz said the findings could enable doctors to test quickly for these biological markers when a patient is admitted to…
The U.S. Food and Drug Administration approved Ofev (nintedanib) capsules to slow the rate of decline in pulmonary function in adults with interstitial lung disease associated with systemic sclerosis or scleroderma, called SSc-ILD. It is the first FDA-approved treatment for this rare lung condition. “Patients suffering from scleroderma need effective therapies, and the FDA supports the efforts…
Cigarette smoke can make MRSA bacterial strains more resistant to antibiotics, new research from the University of Bath has shown. In addition cigarette smoke exposure can make some strains of Staphylococcus aureus – a microbe present in 30-60% of the global population and responsible for many diseases, some fatal – more invasive and persistent, although the effect is not universal across all…
It appears that an influenza vaccine does not just work when it comes to influenza. A new study shows that elderly people who have been admitted to an intensive care units have less risk of dying and of suffering a blood clot or bleeding in the brain if they have been vaccinated. And this is despite the fact that they are typically older, have more chronic diseases and take more medicine then…
New research has found that antibiotic-resistant strains of Klebsiella pneumoniae, an opportunistic pathogen that can cause respiratory and bloodstream infections, are spreading through hospitals in Europe. Certain strains are resistant to the carbapenem antibiotics that represent the last line of defence in treating infections and are therefore regarded as extremely drug resistant (XDR).
In view of the increase of multidrug-resistant organisms (MDRO), the WHO has declared antibiotic resistance one of the biggest threats to global health. MDROs have become a major problem particularly in hospitals. Professor Dr Georg Häcker from the Institute for Microbiology and Hygiene at the University Hospital Freiburg, explains some strategies to prevent hospital-acquired infections (HAIs).
Many countries across the world are challenged with a rising number of incidences of multi-drug resistant (MDR) organisms infecting the population, and for several years, a clear pattern of increased resistance has emerged in southern and eastern European countries. For example, in countries such as Italy, a reduced number of therapeutic options remain available for highly pathogenic infections,…
With a case fatality rate of 35 percent, a Middle East respiratory syndrome-related coronavirus (MERS-CoV) infection – also called camel flu – is a dangerous disease. About seven years ago, when the virus was first isolated, mortality was close to 100 percent since only severe infections that led to the patient being in intensive care were recorded. Today the environment of each victim is…
Sixty-two percent of Germans fear antibiotic resistance, according to a survey recently conducted by the German Federal Institute for Risk Assessment. ‘Patients colonised by multi-resistant pathogens are particularly scared. But many of these fears are rooted in misunderstandings,’ explained Professor Mathias Pletz at the Congress for Infectious Diseases and Tropical Medicine (KIT).
The topic of artificial intelligence (AI) was omnipresent at RSNA2018, the annual meeting of the Radiological Society of North America. From the opening presidential address, throughout scientific sessions and educational presentations, to the vendors’ technical exhibition, around 53,000 attendees learned about pioneering new products, research, plus challenges and opportunities to implement…
At the National Reference Centre for Invasive Fungal Infections (Hans-Knöll Institute Jena) and the Institute for Hygiene and Microbiology, Würzburg University, Professor Oliver Kurzai and team utilise the fast and user-friendly β-D-Glucan Test, supplied by Fujifilm Wako Chemicals Europe GmbH, to check immunocompromised patients for signs of life-threatening, invasive fungal infections.…
Mariette Barbier, an assistant professor in the West Virginia University School of Medicine, and her research team are investigating ways to keep cystic fibrosis patients and other at-risk populations—including patients hospitalized for severe burns or recovering from major surgery—from catching this deadly illness.
Point-of-care ultrasound (POCUS) has become an important adjunct to clinical diagnosis and procedural guidance in the Pediatric Emergency Department (PED), supported by literature demonstrating that its use can improve patient safety and expedite life-saving care. POCUS further helps to reduce costs and children’s exposure to ionizing radiation. Not only is POCUS ideally suited for…
Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. Scientists know little about the early stages of the condition; however, physicians must act fast. Every hour that passes without one or more of the few treatments available increases the risk of death.
A team of researchers at the University of Cologne's Faculty of Medicine and the German Center for Infection Research (DZIF) use a novel immunochromatographic method to detect bacteria that are resistant to the antibiotic group carbapenemes within 20 to 45 minutes from blood cultures with 100 percent certainty.
Doctors working in the eight-bed Paediatric Intensive Care Unit (PICU) at the Ramón y Cajal University Hospital in Madrid extensively use point-of-care ultrasound to evaluate the condition of critically ill children, and they find it essential in their work, as Dr José Luis Vázquez Martínez, Head of PICU at Hospital Ramón y Cajal, with over 25 years’ experience in paediatric intensive care…
When delegates from around 150 countries converge on Munich for ESC Congress 2018 they will no doubt reflect on what they themselves eat. Yes, nutrition is up for debate, questioning, for example, whether weight loss therapies can also prevent heart attacks and strokes. Results from the CAMELLIA-TIMI 61 trial of 12,000 overweight individuals with established cardiovascular disease or diabetes…
Imagine a pathogen that infects completely healthy people and can cause blindness in one day and flesh-eating infections, brain abscesses and death in just a few days. Now imagine that this pathogen is also resistant to all antibiotics.
Scientists from the German Cancer Research Center (DKFZ) have been studying how the immune system succeeds in keeping pathogens in check. For the first time, the researchers have now discovered antibodies that are capable of disarming not only one specific bacterium but a whole variety of microorganisms at once. The newly discovered antibodies recognize a tiny sugar structure found on the surface…
Gram-negative pathogens are responsible for half of all healthcare-associated infections and their ability to resist traditional antibiotics makes them more dangerous for seriously ill patients in a healthcare setting. The need for new approaches to treat these pathogens is essential and there are a number of trials trying to find suitable answers. One of them is the RESTORE-IMI 1 pivotal Phase…
Beta-lactam antibiotics, including penicillin, are one of the most widely used classes of antibiotics in the world. Though they’ve been in use since the 1940s, scientists still don’t fully understand what happens when this class of drugs encounters bacteria. Now, researchers at the University of Notre Dame have elucidated how an enzyme helps bacteria rebound from damage inflicted by…
Synchronised efforts between preventive medicine and immunology enable powerful vaccination strategies in a Spanish seniors hub. Efficient prevention also comes with proper infection control and regulating antibiotics use in primary care, local expert in preventive medicine explained in an exclusive interview with EH. Working in a small structure has its perks, one of which is that departments…
WHO’s first release of surveillance data on antibiotic resistance reveals high levels of resistance to a number of serious bacterial infections in both high- and low-income countries. WHO’s new Global Antimicrobial Surveillance System (GLASS) reveals widespread occurrence of antibiotic resistance among 500 000 people with suspected bacterial infections across 22 countries.
Pneumonia, and other serious lung complications, after major abdominal surgery were halved when patients were seen by a physiotherapist before surgery and taught breathing exercises that the patient needed to start performing immediately on waking from the operation, finds a trial published by The BMJ today. The researchers say their results “are directly applicable to the tens of millions of…
Bacteria not only develop resistance to antibiotics, they also can pick it up from their rivals. In a recent publication, Researchers from the Biozentrum of the University of Basel have demonstrated that some bacteria inject a toxic cocktail into their competitors causing cell lysis and death. Then, by integrating the released genetic material, which may also carry drug resistance genes, the…
Testing for fever, high pulse rate, crackly breath sounds, and low oxygen levels could be key to helping GPs distinguish pneumonia from less serious infections, according to a large study published in the European Respiratory Journal. Pneumonia is a severe lung infection that can be life-threatening and often requires treatment with antibiotics. However, it is notoriously difficult to…
DNAe, the inventor of semiconductor-based genomic analysis technologies, and the developer of a new, game-changing test for bloodstream infections that can lead to sepsis announced new data on its test for bloodstream infections, LiDia BSI. The data demonstrates the ability of the LiDia BSI closed cartridge-based test to rapidly identify low levels of bacterial and fungal pathogens and resistance…
‘Ultrasound plays a key role in diagnosis and monitoring of treatment in the A&E department,’ emphasises Professor Joseph Osterwalder, Medical Director of the Cantonal Hospital in Appenzell, Switzerland. ‘I cannot imagine emergency medicine without ultrasound.’
During our European Hospital interview with specialist in microbiology, virology and infection epidemiology Beniam Ghebremedhin MD, from the University Hospital Wuppertal, spoke about the impact of migration on infections, and ways to tackle the problem of multiresistant pathogens. ‘There is a lack of specialists in infectious diseases, for direct patient care on hospital wards as well as in…
With a scarcity of lungs available for transplantation, the use of lungs from donors older than age 60 has been shown to achieve reasonable outcomes and should be considered as a viable option, according to research published online in The Annals of Thoracic Surgery. “The availability of suitable donor lungs for transplantation continues to be a major obstacle to increasing the number of lung…
Multidrug-resistant organisms (MDRO) are keeping infection specialists worldwide on their toes. One of these specialists travelled all the way from Leipzig to India to gain insights in one of the sources of the problem.
For years, medical investigators have tried and failed to develop vaccines for a type of staph bacteria associated with the deadly superbug MRSA. But a new study by Cedars-Sinai investigators shows how staph cells evade the body’s immune system, offering a clearer picture of how a successful vaccine would work.
Respiratory tract infections in young children are linked to an increased risk of asthma and worse lung function in later life, according to new research to be presented at the European Respiratory Society International Congress.
While new agents to fight virulent pathogens are in the pipeline, a new study pinpoints where a recent addition is already being applied in the clinic.
Cardiac surgeons are successfully performing more extensive surgical repairs of type A aortic dissection—one of the highest risk operations in cardiothoracic surgery. These new surgical techniques, along with improved postoperative care, are resulting in better long-term outcomes and lower rates of complications.
FUJIFILM SonoSite has given two M-Turbo point-of-care ultrasound systems to the non-governmental sea rescue organisation Proactiva Open Arms, based in Badalona, near Barcelona, to support its efforts in rescuing refugees.
Using computer-based simulations and mouse experiments, researchers at the Helmholtz Centre for Infection Research (HZI) in Braunschweig and at the Otto von Guericke University Magdeburg (OVGU), have disentangled the effects of pro-inflammatory signalling molecules on the postinfluenza susceptibility to pneumococcal coinfection.