A certain type of cells, called aneuploid epithelial cells, are usually associated with breast cancer. However, new research reveals that they can also be found in healthy women.
A new imaging technique reduces skin tone bias in breast cancer detection, improving visibility across diverse skin tones.
New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
The year: 2034. Breast cancer patients benefit from perfectly personalised diagnostics and therapies. The tedium of follow-up treatments is a thing of the past, thanks to AI, augmented reality and robotics. Just a tale from the realm of science fiction, or could this soon be clinical reality? At the annual meeting of the German Senologic Society, Prof Dr Marc Thill from the Agaplesion Markus…
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.
Minimally invasive surgical interventions, innovative imaging and the use of AI: At the upcoming EUSOBI congress in Lisbon, experts present and discuss the latest advances in breast imaging. We spoke with Tanja Brycker from Hologic ahead of the event about new trends in women’s health, the company’s investment in innovation and education, and what the future of mammography looks like with the…
Measuring the calcium build up in the arteries of the breast, researchers have developed an AI-generated score for predicting cardiovascular disease in women from their mammograms.
A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.
Evidence of the superiority of tomosynthesis for breast cancer detection is stacking up, with new results from a 10-year study further demonstrating the 3D imaging technique's benefits.
Two international studies presented at the ESMO Congress 2024 show no increase in recurrence or new breast cancers in women who breastfeed after being treated for breast cancer.
Mammography can lead to “false positives,” meaning they do not result in a breast cancer diagnosis. This may discourage some women from future screenings, according to a new study.
The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.
Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.
After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
Researchers have discovered an Achilles heel of migratory metastatic cells: They now investigate how the cell death mechanism ferroptosis can be utilized for future cancer treatments.
Sentinel lymph node biopsies can help detect breast cancer – but not every patient benefits from the procedure. New research finds that a simple EHR prompt can prevent unnecessary surgery.
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
Although the Covid-19 pandemic is behind us, healthcare facilities continue to experience workflow challenges and resource constraints impacting women’s health and a patient’s ability to receive a timely diagnosis. Clinical specialties like breast radiology and cytology are especially susceptible to these issues and continue to experience backlogs, which impact their ability to deliver timely…
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
Using artificial intelligence (AI), breast radiologists in Denmark have improved breast cancer screening performance and reduced the rate of false-positive findings.
Current AI systems for detecting breast cancer from mammography exams are more likely to produce false-positive results in black women and older patients, a new study finds.
A study highlights performance differences in computational pathology systems, depending on demographic profiles associated with histology images. The researchers also propose a way to fix this bias.
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
A team of Danish and Dutch researchers has combined an AI diagnostic tool with a mammographic texture model to improve the assessment of short- and long-term breast cancer risk. This new approach represents a significant step forward in refining the ability to predict the complexities of breast cancer risk.
Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
A clinical trial has revealed the effectiveness of '3D mammography' in reducing by almost half the incidence of interval breast cancer appearing between two rounds of screening.
A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.
A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
Awareness of the importance of women’s health is on the rise, but many challenges remain: At ECR 2024 in Vienna, we spoke with Hologic about their continued evaluation of healthcare efforts for women. At the congress, the company also shared how AI could be used to mitigate the effects of medical staff shortage.
Researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating memory impairment and other cognitive effects of chemotherapy.
An international study has revealed that MRI monitoring in women with mutations in the BRCA1 genes significantly reduces breast cancer mortality without the need for preventive mastectomy.
Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer which could revolutionise how the disease is diagnosed and treated in the future.
Hologic, Inc. unveils new research in artificial intelligence (AI) and offering innovative educational opportunities at the annual European Congress of Radiology (ECR) in Vienna, Austria.
An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.
Breast cancer has no “one size fits all” therapy approach: subtypes differ significantly in malignancy, progression, and treatment response. Therefore, the more is known about the type of carcinoma in a patient, the better the outcome. At the annual scientific EUSOBI meeting in Valencia, Dr Ramona Woitek pointed out the potential of novel imaging techniques and computational image analysis…
Ordering preoperative breast MRI exams of diagnosed breast cancer patients used to be controversial: Did they aid surgical planning better than the combination of mammography and breast ultrasound? Or did their findings cause overtreatment, specifically mastectomy, when breast-conservation surgery would have sufficed? New research has now settled the issue.
Chronic stress can have a significant impact on health, from an increased risk for heart disease to a greater susceptibility of cancer metastasis. New research points out the underlying mechanisms.
GE HealthCare and the European Society of Radiology (ESR) renew their collaboration for the upcoming European Congress of Radiology (ECR) from February 28 to March 3 in Vienna.
Breast MRI is increasingly being used as a primary breast cancer screening exam for young women. It brings benefits in women with dense breasts, who are at an elevated risk of developing breast cancer. The technique is also being ordered as a supplemental screening exam following mammography or breast ultrasound for women of all ages at high risk. But use of breast MRI as a screening tool is…
A newly-developed biosensor could be an alterative to MRI and mammography for breast cancer screening. The handheld device uses saliva on test strips to determine whether cancer is present.
On 9 December 2023, NovaLife Polyclinic, with over 15 years of experience in the private healthcare sector in Timișoara, proudly inaugurated its state-of-the-art branch in the vibrant capital city of Bucharest.
A new breast imaging technique provides high sensitivity for detecting cancer while significantly reducing the likelihood of false positive results, according to a new study.
Researchers in Singapore have developed an AI-based software to assist in the early detection of breast cancer. Using thermal imaging, the program assesses the malignancy of a tumour.
Breast surgery is a traumatic experience for a woman, no matter whether breast-conservation surgery (BCS) or a mastectomy. Trauma levels are greatly enhanced, if pathological evaluation findings of an excised breast tumour following a lumpectomy suggest that additional cancer may still be in the margins, and a second surgical procedure is required. A new system with the ability to accurately…
Ahead of World Cancer Day on 4 February, scientists are revealing a cutting-edge artificial intelligence (AI) tool designed to help grade cancer, by analysing cell division.
Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.
Academic labs and biotech firms pioneer multi-cancer early detection with emerging technologies. Screening for multiple cancers with a simple blood or urinary draw could be a game-changer. Two research teams in particular have advanced the field.
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
A simple blood test could help diagnose patients with glioblastoma, the deadliest form of brain cancer, sparing them from undergoing invasive and highly-risky surgery, report UK researchers.
HighlightsExceptional performance for high speed tomo reading with up to 75%¹ faster image loadingNext-gen AI-powered tools enable workload reduction up to 63%² and up to 10%³ increased accuracy in diagnosisFull spectrum multimodal reading with motion corrected MRI data, subtraction calculation and advanced analytical toolsComprehensive double-blind reading management with…
HighlightsCompact AI-powered diagnostic platform, ergonomic designDeepInsight technology: proprietary Artificial Intelligence deep learning know-howWide range of transducers for all applicationsComprehensive diagnoses of hepatic diseasesUseful tools to help diagnose breast cancerSeamless workflow: Protocol assistant, Auto Measurements
HighlightsMulti-disciplinary Premium platform, ergonomic designDeepInsight technology: proprietary Artificial Intelligence deep learning know-howWide range of transducers for all applicationsComprehensive diagnoses of hepatic diseasesAdvanced application with fusion imaging to support procedure guidance and treatment evaluationUseful tools to help diagnose breast cancerSeamless workflow: Protocol…
HighlightsNew AI-powered diagnostic multi-disciplinary platform, ergonomic designDeepInsight technology: proprietary Artificial Intelligence deep learning know-howWide range of transducers for all applicationsComprehensive diagnoses of hepatic diseasesAdvanced application with fusion imaging to support procedure guidance and treatment evaluationUseful tools to help diagnose breast cancerSeamless…
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
Men with gynaecomastia (non-weight-related enlarged breast tissue) may be at heightened risk of an early death before the age of 75, suggests the first study of its kind.
The climate crisis and AI – arguably two of the most hotly-debated and relevant topics of our time – share an intricate relationship: While computation of complex AI routines commands an immense carbon footprint, it is these algorithms that might be the very key to mitigate the effects of global warming. In a dedicated session at ECR 2023, radiologists explored the societal and environmental…
An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.
While having more centers adopt digital breast tomosynthesis (DBT) for breast cancer screenings into their practice is a positive change, it also presents some challenges for radiologists—particularly the increased number of images for radiologists to review. This challenge has paved the way for AI to offer innovative workflow solutions for radiologists that do not sacrifice accuracy.
Researchers and clinicians at Washington University in St. Louis found a way to improve diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes.
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
University of Waterloo researchers are pioneering a method to detect breast cancer in women early enough for them to receive life-saving treatment.
Mammography screening is vital in breast cancer prevention, but about 3% of women receive a false-positive result. This not only causes worry, but also increases risk of developing breast cancer.
A new device that acts like a GPS to locate and remove breast and lymph node tumors was tested for its safety and effectiveness in a feasibility study - with promising results.
Clinicians who show more empathy promote better psychological health among breast cancer patients, according to a new US study examining how oncology doctors facilitate psychological well-being.
A team of researchers from Vienna has discovered that dormant breast cancer tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein.
A team at the University of Bristol has developed a robot manipulator that could carry out clinical breast examinations. The developers hope the device will revolutionise breast health monitoring.
A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.
At the EUSOBI congress in Valencia, Hologic showcases its women's health portfolio, announces global partnerships for breast health - and even brings a sweet treat for the congressgoers.
US researchers have discovered that radiation therapy combined with two types of immunotherapy can control tumors in preclinical models of triple negative breast cancer.
Modern cancer therapies are tough on the tumours, but often, also on the heart of the patients. The “CARDIOCARE” project aims to reduce the cardiac burden of anti-cancer therapies through more patient-tailored treatment approaches. At the ESC 2023 cardiology congress, Professor Katerina Naka from the project’s consortium explained why older patients are at the highest risk of cardiotoxic…
A genetic test for BRCA1 or BRCA2 gene mutations may drive women to undergo breast cancer surgery, even though their risk might not even be drastically affected by this, a new study finds.
Chemotherapy can be an effective means to fight breast cancer, but under certain circumstances, the treatment can cause dormant cancer cells to re-awaken, new research finds.
Cancer has become strikingly more common in people under 50 in the past three decades, an international research team finds. The reseachers explore what this means for future death tolls.
Mammographic screening is used to detect breast cancer, but is prone to false findings. Could an AI reader help improve this? UK researchers compared the performance of man and machine.
Where are the beginnings of breast cancer? A team of researchers at Kyoto University has revealed the mechanism by which breast cancer is formed in the cells of mammalian epithelium.
Experts from Brigham and Women’s Hospital have tasked ChatGPT to generate recommendations for cancer treatment – with some promise, but ultimately inadequate results.
Can per- and polyfluoroalkyl substances (PFAS) increase the risk of breast cancer? A new study by US researchers examines the effects of the so-called “forever chemicals”.
A new analysis exploring the finances of bringing new cancer drugs to market has found that precision oncology drugs could be $1 billion cheaper to develop than non-precision drugs.
Centralized review of slides combined with telepathology has opened up the potential for a dramatic reduction in the waiting times for breast cancer patients to start their therapy. Jan Hudecek from the Netherlands Cancer Institute outlined his team’s framework for multi-centre clinical trials with centralized digital pathology review at the 9th Digital Pathology and Artificial Intelligence…
One less thing to worry about: Mental health isues such as depression and anxiety are not linked to higher risks for most types of cancer, according to a new analysis of multiple studies.
A machine learning model found that background parenchymal enhancement (BPE) on breast MRI is an indicator of breast cancer risk in women with extremely dense breasts.
Experts have highlighted how precision pathology using Artificial Intelligence can provide an effective alternative to molecular diagnostics. This, say a team from the Karolinska Institutet (KI) in Stockholm, Sweden, can also offer multiple advantages within a clinical setting and support risk stratification.
A new safety analysis finds AI-supported mammography analysis is as good as two breast radiologists working together to detect breast cancer, almost halving the screen-reading workload.
While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.
With the recent recommendation changes from the European Council in 2022, how radiologists screen for breast cancer is changing. Mammography has long been an essential technology in screening for breast cancer, and in the recommendations the Council formally recognized the advantages of digital breast tomosynthesis (DBT). This landmark acknowledges the research on and benefits of DBT, advocating…
A new device, designed by MIT researchers, could detect breast cancer earlier. The scanner, which can be incorporated into a bra, could allow more frequent monitoring of high-risk patients.
Researchers have unveiled a key mechanism of breast cancer cells to infiltrate lymph nodes. The discovery may lead to new metastasis-blocking treatments and improve patients’ lives.
Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer. According to the experts, adipocytes play a vital role here.
Scientists have designed an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery — critical information that can guide treatment decisions.
Researchers from Queen’s University Belfast have created personalised 4D printed “smart” implants for breast cancer management - a first for this technology.
Treatment times for radiotherapy could be reduced for some early breast cancer patients, according to a trial led by University of Cambridge and The Institute of Cancer Research, London.
What will the future structure for artificial intelligence in health imaging across Europe look like? While the algorithms show great promise in collecting, storing, analysing, and using data to advance healthcare, delegates to a session on the topic at ECR 2023 in Vienna, also heard that it was important for the use of AI to move from research and more toward practical applications for patients.…
Surgical robots are becoming widespread in operating theatres, delivering accuracy and safety. An overview of the main systems, principal operators, the market and European initiatives in this field.
A new US-led study shows that astrocyte brain cells play an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.
Genomic sequencing panels as part of personalised cancer treatment have been found to only benefit one in 20 patients they are currently used for, according to a study by CNIO.
An MRI invention from engineers at the University of Waterloo reveals better than many existing imaging technologies how Covid-19 can change the human brain.
A new study suggests that deep learning–based computer-aided diagnosis (CAD) for breast lesion classification on ultrasound can significantly improve radiologists' diagnostic performance.
New research from the University of Helsinki increases the understanding of ovarian cancer: the identification of new subtypes could help discover new treatments.
Patients with early-stage breast cancer who have an elevated risk of having tumour recurrence now have the option to take a course of radiotherapy following breast conservation surgery that is only three weeks long, half the time of conventional radiotherapy treatment.
Artificial Intelligence (AI) could identify patients at increased risk of side effects from radiation treatment for breast cancer, according to researchers at the University of Leicester.
AI can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer, according to a new study. This could prove useful for triage in low-resource settings.
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
A group of researchers has illustrated the mechanistic pathway for PTEN-deficient breast cancer and successfully tested a method of countering the downstream effects of immune system evasion by tumors.
Women with triple-negative breast cancer who received multiple antibiotic prescriptions within three years after their cancer diagnosis were more likely to experience disease recurrence and to die from their cancer.
Women working in health care who are regularly exposed to radiation from X-rays and other imaging procedures need better ionizing radiation protection.
Mammography has been an essential imaging technology for breast cancer detection for decades. As the industry has continued to innovate, one advancement in mammography has particularly changed the landscape of breast imaging: digital breast tomosynthesis (DBT), also known as 3D mammography.
Ultrasound is an effective standalone diagnostic method in patients with focal breast complaints, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA). Focal breast complaints can refer to pain, lumps, nipple discharge or other symptoms and conditions confined to a specific area of the breast.
As ChatGPT becomes more popular among those seeking health advice, researchers try to find out whether the information provided by the AI chatbot is reliable and accurate.
A novel imaging modality that can visualize the distribution of medical radiopharmaceuticals with very fine resolution has been developed and successfully tested.
In a study of over a million women, digital breast tomosynthesis (DBT) showed improved breast cancer screening outcomes over screening with standard digital mammography alone.
Scientists have discovered why breast cancer cells that have spread to the lungs may ‘wake up’ following years of sleep - forming incurable secondary tumours.
Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).
A new study calculated the economic cost of cancers around the world, helping policymakers allocate resources and enact policies to curb the increase in cancer-related death and disability.
Radiotherapy does not improve survival rates in older patients with early breast cancer, new research suggests.
The newly founded UK Focused Ultrasound Foundation is dedicated to advancing the development and adoption of the technology, which can be used to non-invasively treat tissue deep in the body.
A new imaging approach using ultrafast MRI shows potential in predicting upgrade of ductal carcinoma in situ (DCIS) to invasive breast cancer at surgery.
Evidence that radioembolization, a trans-arterial therapy, is safe and stops disease progression in metastatic breast cancer is increasing, a prominent American interventional radiologist showed at the Spectrum conference in Miami.
Philips is an active participant in the new European Federation for Cancer Images consortium (EUCAIM) – a project launched in the run-up to World Cancer Day 2023.
Compared to other common supplemental screening methods, breast MRI was superior at detecting breast cancer in women with dense breasts, according to a new study.
A Korean research team successfully changed the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.
A new approach on the genetic tool CRISPR-Cas9 could reduce the risk of unwanted mutation, making it safer for use in humans, Dutch researchers have found.
The distinction between primary tumors and metastases can be made quickly and accurately in brain tumors using radiomics and deep learning algorithms, a new study shows.
Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.
Researchers generated human mini bones in the lab which mirror the composition and function of human bone - a step toward the development of future patient-tailored models of bone cancers and tumors.
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research.
Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.
A cancer researcher and consultant has estimated for the first time how many women are living with secondary breast cancer in England – in new research which could help to shape cancer services.
Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way. The method showed promising results against various cancers in lab tests on mice.
Scientists managed to identify and kill breast cancer cells that evade standard treatments in a study in mice. The is a step towards the development of new treatments to prevent relapse in patients.
Tapping the thriving Radiology AI ecosystem, Bayer recently announced three collaboration agreements for its digital platform, Calantic Digital Solutions, as well as an AI accelerator program.
Breast cryoablation is an emerging treatment for early-stage, localized breast cancer that destroys malignant tumours by freezing them. During the past decade, it has been increasingly utilized as an alternative to lumpectomy, but its long-term benefits compared to other breast cancer treatments are still unproven.
The need for breast cancer screening of transgender individuals has been a topic of uncertainty until recently, due to lack of reliable patient data, consensus by radiologists, published research, and recommended guidelines. A 2021 survey of Society of Breast Imaging (SBI) members revealed that ‘breast radiologists differ in their practice and knowledge regarding screening of transgender…
An international team highlights the importance of localising BRCA1 and BRCA2 gene mutations for the treatment of ovarian cancer.
This summer, The European Commission launched I3lung, a new research initiative as a part of Horizon Europe, the EU’s research and innovation program. This research initiative aims to create a cutting-edge, decision-making tool to help clinicians and patients select the best lung cancer treatment based on each patient’s specific needs and circumstances.
New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread.
One robot supports the surgeon’s control of tiny instruments, while another automatically keeps an eye on what is happening: With this novel combination, surgeons in Münster have successfully performed fully robot-assisted microsurgery for the first time. Presenting the new procedure at the Hornheide Specialist Clinic, the experts explain how the interaction of both robotic systems ensures…
New tests can identify over 50 types of cancer and boost detection of traditionally elusive cancers from tumour DNA in blood, researchers showed at the ESMO congress in September. These multi-cancer early detection (MCED) tests in development can spot common cancer signals and predict where the signal comes from in the body, results from a prospective investigation suggest.
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease.
A session at the Medica Health IT Forum will focus on the important topic of gender-sensitive medicine and raise critical points within the field. While a key challenge remains in raising awareness and acceptance that there are medical differences between men and women, session chair Dr Martina Kloepfer points out that gender-sensitive medical care is the ‘lowest common denominator of…
The risk of developing breast cancer is higher in breasts with high density. But why is that? Researchers at Linköping University have shown major biological differences that promote cancer growth.
Researchers in Finland have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumours.
Women with high-risk breast lesions (HRLs) and no family history of breast cancer or BRCA mutations are generally considered to be at moderate risk of developing breast cancer. Breast cancer screening guidelines suggest breast MRI be considered as a supplement to mammography. But is this expensive exam necessary?
A simple 'liquid biopsy' blood test could help guide the treatment of children with the cancer rhabdomyosarcoma, a new study reports.
What if a test analysing cervical cells from a gynaecological swab could be used to detect four different female cancers at an early stage and also predict cancer risk over a healthy woman's lifetime? Researchers at the EUTOPS Institute in Innsbruck, Austria, are developing tests to do just that for breast, ovarian, cervical, and endometrial cancer detection.
Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…
Many women diagnosed with breast cancer can be cured with surgery, radiotherapy and medical treatment. Swedish researchers explore whether physical exercise can support the anti-tumour effects.
Researchers in Munich have developed a novel model system that can be used to precisely track the growth steps and three-dimensional arrangement of pancreatic cancer cells.
Scientists in Italy discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells. They also devised an experimental therapy to bypass or prevent this.
It’s widely known that more than 70% of today’s medical decisions involve the results of laboratory tests, but the insights clinicians derive from these tests today may only be scratching the surface of their potential.
Cancer – one word that turns the patients’ world upside down. In addition to uncertainty and fear, they often face an unnerving series of exams and treatments. With its new One-Stop Clinic concept, GE Healthcare now wants to help make this journey as smooth as possible. At a single location, in an environment designed for comfort, the patients undergo all necessary steps within a short period…
The hearts of men and women are different – while this insight has been established for quite some time now, it might even surprise cardiologists just how deep these differences really run. In her presentation at this year’s ESC, Diana Bonderman, MD, gave a comprehensive roundup on sex differences in risk factors and subtypes of heart failure.
When double reading screening mammograms, radiographers trained for the task perform as well as radiologists in key areas, according to a new publication.
Researchers from the University of Bern and Inselspital provide an overview of the latest technologies in precision oncology. Translating these into clinical application is still a major challenge.
A new study shows that women with a breast cancer diagnosis undergoing procedures for fertility preservation are not at increased risk of recurrence of the disease or disease-specific mortality.
The interplay between the patient’s BMI, tumour size and cancer-specific proteins is of importance for the prognosis of breast cancer, a study from Sweden shows.
Clinical laboratories need to be proactive to attract transgender patients for testing and to ensure that they are comfortable with the services provided. This issue is of great importance to the American Association for Clinical Chemistry (AACC), which conducted a scientific session on transgender health at its recent annual meeting in Chicago.
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
At the ECR 2022 congress in Vienna, Hologic went beyond just showcasing new systems for women’s health. Additional focus topics were the mitigation of the pandemic impact on screening programmes and the situation of women around the world without access to advanced diagnostic technologies – or even the most basic standards of healthcare.
Hospital patients who develop infections where 10% of sufferers die will be offered double the traditional course of antibiotics in a new trial.
Patients with multiple architectural distortion (AD) identified on digital breast tomosynthesis may benefit from biopsy of all areas, given the variation of pathologic diagnoses across individuals.
A Europe-wide project aims to improve medical radiation protection for patients and staff by better understanding and evaluating the health effects of exposure to low-dose ionising radiation resulting from diagnostic and therapeutic procedures.
Contrast-enhanced mammography (CEM) has gone a long way since it was first approved by the Food and Drug Administration (FDA) in 2011. An Italian expert explained how useful the modality has become in breast imaging in a dedicated course at ECR 2022.
Multiparametric ultrasound (MPUS) has proven its value in the abdomen – now, the technique is increasingly moving towards peripheral areas such as breast and testis imaging, experts showed in a dedicated session at ECR 2022.
Rapid technical advances in ultrasound and increasingly tight healthcare budgets call for a change in ultrasound practice, experts explained in a session at the ECR in Vienna. Two experts presented possible models for the next two decades.
Physicians use AI-powered technology for faster and earlier detection of diseases. At ECR Overture, Dr Steven Schalekamp, PhD, discussed the application of AI for chest radiography in paediatrics.
Contrast-enhanced mammography (CEM) may be a useful alternative test for neoadjuvant therapy (NAT) response assessment in patients with breast cancer who are unable to undergo MRI.
Researchers have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.
"Crown-like structures" surrounding breast tumors in overweight and obese patients could hinder their response to therapy. The findings of this study could potentially be used to improve personalized treatment for patients.
A combination of digital pathology and quantitative biomarker analysis in the emerging concept of ‘smart’ cytology has a potential role in the detection and diagnosis of cancer.
Microfluidic chip inflates and deflates balloons in a sleeve to promote fluid flow in the lymphatic system.
Reaching out across 15 hospitals and a population of six million people, a network established by the National Pathology Imaging Co-operative (NPIC) is an ambitious move to advance digital pathology in the North of England.
Informing a patient about a cancer diagnosis is never an easy task. An Austrian patient has developed a solution that will help radiologists break the bad news as smoothly as possible and guide women through their patient journey.
Computational approaches are being applied on enormous amounts of data from sequencing technologies to develop tools to help clinicians manage cancer more effectively.
Personalised screening, data-driven aproaches: In a dedicated press conference in Paris, French oncologists presented promising research that might bring hope for many cancer patients.
A team of researchers from Singapore has developed a novel magnetic therapy that serves as an effective companion therapy to chemotherapy to enhance treatment outcome for breast cancer.
A major advance demonstrates first multi-organ chip made of engineered human tissues linked by vascular flow for improved modeling of systemic diseases like cancer.
A protein vital in determining the organs affected by metastasis has been identified by Swiss researchers. This could lead to the development of therapeutic approaches to suppress metastasis.
Patients with neurological conditions such as dementia or autism can prove especially challenging for radiographers. A session at the ECR Overture in March gave insights to a patient-focused approach.
A new biodegradable gel improves the immune system’s ability to keep cancer at bay after tumors are surgically removed.
Big data is transforming diagnosis and medical care, but the critical challenge remains over how to equally apply the benefits it delivers across real-world clinical settings, according to industry expert Prof Benoît Macq.
Scientists from Hokkaido University have identified new targets for treating Adult T-cell leukemia/lymphoma (ATLL), an aggressive form of blood cancer with existing drugs.
A major new study shows that artificial intelligence (AI) is a promising tool for breast cancer detection in screening mammography programs.
Liquid biopsy performed on serum samples taken from breast cancer patients can provide increasingly accurate information on progression and enable earlier detection of recurrence.
Synthetic correlated diffusion makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.
A software based on deep learning with convolutional neural networks can accurately and consistently classify breast density on mammograms according to BI-RADS criteria.
Hologic and the Women's Tennis Association (WTA) kicked off a multi-year partnership, launching a joint vision to achieve greater wellness and equality for women.
When it comes to imaging stable cardiac chest pain, which modality should be used as the first-line test to investigate coronary artery disease: CT or MRI? Radiologists discussed the strengths and limitations of the two approaches in a lively Pros and Cons session at ECR Overture.
Groundbreaking technologies have improved our ability to accurately diagnose breast cancer and reduce callbacks, focusing on compassionate care for patients as they move along their breast health journey.
When it comes to your patient’s health, certainty matters. Breast biopsies play a vital role in the continuum of care for women, providing insights into mass and calcification identification so you can make the best-informed decisions.
Close liaison between pathologists and data scientists is pivotal in the successful introduction of digital pathology and artificial intelligence (AI) into clinical workflows, according to one of France’s leading pioneers in the field.
Molecular radiotherapy shows great potential in becoming a more mainstream treatment for cancer, but the field is being hampered by a limited radionuclide supply.
UK researchers have found that a new type of ultrasound scan can diagnose most prostate cancer cases with good accuracy in a clinical trial involving 370 men.
Annual MRI screenings starting at ages 30-35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes, according to a new modeling analysis.
Physicists from Leipzig University have developed gene expression tests to examine whether additional chemotherapy is necessary and really effective after breast cancer surgery.
Periprosthetic joint infection (PJI) can be an enormous challenge for orthopaedists and trauma surgeons. Antibiotic-loaded bone cement is an important element in a prevention strategy.
Scientists have discovered a means of identifying the risk of breast and ovarian cancer by measuring epigenetic changes in cervical samples from over a thousand women.
Faulty versions of the BRCA1 and BRCA2 genes are well known to increase the risk of breast and ovarian cancer. Now, they have been linked to several other cancers, including those that affect men.
Under the roof of integrated diagnostics, radiology, laboratory medicine and pathology are forming a powerful alliance. Hedvig Hricak, MD, PhD, explains the potential for cancer patients and details the role of radiologists within the construct.
Mark Nicholls reports from the National Cancer Research Institute (NCRI) virtual Festival, with four expert speakers discussing the role of liquid biopsy in cancer detection.
When the coronavirus first struck in the US, hospitals in New York City were the first to feel the impact. Radiologists Professor Judy Yee, M.D., and Mark C. Liszewski, M.D., describe the lessons learned and talk about their firsthand experiences.
Artificial intelligence (AI) models that evaluate medical images have potential to speed up and improve accuracy of cancer diagnoses, but they may also be vulnerable to cyberattacks.
Artificial intelligence (AI) is changing our healthcare systems. It can help us detect diseases earlier, improve patient care and reduce healthcare costs. However, there is still a lack of trust, of rules and safety regulations and of broad data pools. How can we use AI successfully in healthcare systems and what role will it play in the future?
Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation. While the risk of getting breast cancer is higher for older people, it can strike at any age. Studies show that 5% to 7% of females with breast cancer…
Researchers have developed an ultra-thin wireless device, called osseosurface electronic, that grows to the surface of bone and could someday help physicians monitor bone health and healing over long periods.
Intrauterine contraceptive devices (IUDs) appear to have systemic effects on the body like those of hormone replacement therapy, according to a breast MRI study being presented at the annual meeting of the Radiological Society of North America (RSNA).
An innovative collaboration has been formed in the UK between academic researchers and industry to develop a rapid integrated liquid biopsy platform for early detection of recurrent breast cancer. Breast cancer specialists Professor Charles Coombes, who is Professor of Medical Oncology at Imperial College London (ICL), and Professor Jacqui Shaw, Head of the Department of Genetics and Genome…
The risk of early breast cancer spreading to another part of the body ranges from 6% to 22%, according to the first results of a large and detailed global study of metastatic breast cancer presented at the Advanced Breast Cancer Sixth International Consensus Conference (ABC 6). The study also shows that certain women face a higher risk than others, including women diagnosed with breast cancer at…
The breast imaging field plays a critical role in women’s health and wellbeing around the globe. Bringing together experts, leaders and innovators from across the breast imaging landscape, the 2021 European Society of Breast Imaging (EUSOBI) Congress comes at a crucial time and represents a pivotal opportunity for the industry as a whole. Taking place online from 4-28 October, 2021, the virtual…
Researchers from Cleveland Clinic have opened a novel study for a vaccine aimed at eventually preventing triple-negative breast cancer, the most aggressive and lethal form of the disease. This phase I trial is designed to determine the maximum tolerated dose of the vaccine in patients with early-stage triple-negative breast cancer and to characterize and optimize the body’s immune response. The…
Together with Imperial College London (‘Imperial’), molecular diagnostics company DNAe has been awarded a UK Knowledge Transfer Partnership (KTP) by Innovate UK to support development of its next generation sequencing (NGS)-based diagnostic platform for use in cancer monitoring. The KTP program connects innovative businesses with academic experts who can help them deliver their ideas. This…
The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don’t eat me" signal, which tells the immune cells to stand back. Tumor cells exploit this CD47-based protection strategy for evading the immune system, by increasing presentation of CD47 on their cell…
Mass spectrometry – a powerful tool for analysing the molecular composition of a tissue sample – is invaluable during cancer surgery. However, mass spectrometers are complex and unwieldy, and certainly a poor fit for an operating room (OR). To create a bridge between the lab and OR, Professor Livia S Eberlin, from Baylor College of Medicine, has developed a very special ‘pen’.
Many of the organ systems found in animals exhibit highly complex structures, which are essential for their various functions. How such structures develop during embryonic development is a central question in biology. Physicists led by Erwin Frey (Professor of Statistical and Biological Physics at LMU Munich) and Andreas Bausch (Professor of Cellular Biophysics at the Technical University of…
Researchers at Karolinska Institutet have developed an AI-based tool that improves the diagnosis of breast cancer tumours and the ability to predict the risk of recurrence. The greater diagnostic precision can lead to more personalised treatment for the large group of breast cancer patients with intermediate risk tumours. The results are published in the scientific journal Annals of Oncology.
New research indicates that MRIs are cost effective for detecting breast cancer for women with very dense breasts detected by mammography. About 10% of women have extremely dense breasts, and current mammography screening guidelines do not recommend additional imaging tests unless there is a strong family history or genetic risk for breast cancer. Such women face two problems. They have increased…
A computer program trained to see patterns among thousands of breast ultrasound images can aid physicians in accurately diagnosing breast cancer, a new study shows. When tested separately on 44,755 already completed ultrasound exams, the artificial intelligence (AI) tool improved radiologists’ ability to correctly identify the disease by 37 percent and reduced the number of tissue samples, or…
Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment.
New data highlights a promising new treatment for individuals with HER2-mutant non-small cell lung cancer (NSCLC).
Customizable to individual patients and requiring less than 10 minutes to prepare and use, new surgical implant coating prevented 100% of infections in mice.
For World Patient Safety Day, Health First Europe (HFE) published a comprehensive insight report on five disease areas that affect millions of European citizens each year and how the European Union could and should do a better job for its citizens.
By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…
A team led by the Garvan Institute of Medical Research has revealed a new approach for classifying breast cancer subtypes based on their cell profile, which could help personalise treatments for patients. By analysing breast cancer biopsies from patients at Sydney hospitals, the researchers revealed more than 50 distinct cancer, immune and connective cell types and states, which could assign…
A new technology that can study which therapies will work on patients with solid cancerous tumours has been developed by scientists at University College London (UCL). Researchers say the tool, which can rapidly test tumorous tissue against different treatments, such as chemotherapy, immunotherapy or radiotherapy, could be used by clinicians to pinpoint the best therapy for a particular patient.
Scientists from the German Cancer Research Center (DKFZ) and the Medical Faculty Mannheim, Heidelberg University, have identified a new growth factor produced by blood vessels that enables tumor cells to metastatically colonize organs.
A solid diagnosis has always been the first step on any patient’s journey to health. However, diagnostic categories are necessarily oversimplifications. In the last decades, medical professionals and scientists have begun to uncover the true variability in patients’ physiological and biochemical make-up that is the principal cause for individual variations in the way diseases present…
The goal of tumour conferences is to determine the best treatment for patients with complex cancers – however, the patient is rarely present. Now, a team of researchers has investigated whether cancer patients can benefit from participating in these meetings.
In an effort to promote access to professional breast imaging knowledge, the European Society of Radiology (ESR) now links to educational materials from DenseBreast-info.org as a resource for its members about the screening and risk implications of dense breast tissue.
Remote 24-hour monitoring for cancer patients receiving chemotherapy helps to better manage side effects and improve quality of life, finds a study published by The BMJ. The researchers say remote monitoring can provide a safe, secure, and “real time” system that optimises symptom management and supports patients to remain at home - and is particularly relevant in the context of the Covid-19…
A researcher at the Technical University of Denmark (DTU) has developed a mathematical model for use in automated image analysis of tissue samples. The model provides the possibility for better and more similar cancer prognosis and treatment.
The Covid-19 pandemic continues to impact people’s health across the world. This goes beyond the disease itself, as healthcare systems adapt how they provide services. Routine screening has been severely affected with screening programmes reduced or paused.
Cancer care and the treatment clinicians can offer patients is being increasingly enhanced by Artificial Intelligence (AI). The technology has a role in diagnosis, with algorithms trained to design and deliver patient care, can match patients to clinical trials they may benefit from, and even help predict outcomes and those at greatest risk.
Pancreatic cancer is one of the deadliest cancers in the world, and one of the most difficult to treat. In 2020, an estimated 495,000 individuals worldwide were diagnosed with pancreatic cancer and an estimated 466,000 died, according to statistics from the World Health Organization’s International Agency for Research on Cancer. Most patients with advanced disease die within a year of…
In a collaboration with the Faculty of Statistics at TU Dortmund and the University Medical Center in Mainz, a research team at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) has developed a test that can be used to predict the success of therapy for breast cancer. Breast cancer is one of the most common tumour diseases worldwide. One in eight women will…
The contribution of Artificial intelligence (AI) has great potential in breast imaging efficiency, Professor Linda Moy MD told attendees at the 2021 Society of Breast Imaging/American College of Radiology (SBI/ACR) Breast Imaging Symposium this April. AI models for breast imaging have focused mainly on the diagnostic classification and detection of breast cancer.
Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation – are completed more than 38 weeks from the time of diagnosis. The observational study, which included more than 28,000 breast cancer patients registered in the American National Cancer Database, is…
Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms. In a paper published in the cancer journal Annals of Oncology, researchers report that the test accurately detected…
Women are missing out on appropriate cardiac care because guidelines and medications often fail to take into account gender and conditions that specifically affect the female population. Women are also underrepresented in clinical trials for new cardiac therapies.
In the emerging era of personalized medicine, risk-based breast cancer screening protocols may be better than the one-size-fits all approach. It’s time to consider adopting them, Jack Cuzick, Ph.D., said in the President’s Address of the 2021 Society of Breast Imaging/American College of Radiology Breast Imaging Symposium.
A breast cancer therapy that requires just one shot of radiotherapy is as effective as traditional radiotherapy, and avoids potential damage to nearby organs, according to a paper by UCL experts.