
News • Oncology
Nanozymes take on brain tumours from the inside
Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.

Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.

Researchers have developed an electrochemical sensor that can detect pancreatic cancer in its early stages. The device offers a simpler, more affordable alternative to conventional tests, which are less accessible.

The incidence of colorectal cancer is rising among younger individuals, sometimes as early as their thirties. The research also shows the challenge of late diagnoses and calls for increased awareness.

A new technique to “prime” a patient's immune system before liver transplantation has proven itself in a first-in-human clinical trial to successfully prevent transplant rejection.

Why does the same genetic mutation cause FCDII in some patients but not in others? Researchers developed organoids to model a brain malformation responsible for drug-resistant epilepsy in children.

Researchers have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease.

As women age, their breast tissue goes through major changes, with the most dramatic changes at menopause, but also during pregnancy and childbirth. A map reveals the impact on breast cancer.

Earlier detection, better outcomes: A new blood test for bowel cancer screening is designed to transform cancer outcomes by moving away from invasive or unpleasant methods.

Two new studies explore the role of the thymus – a small organ in the chest, and possibly a missing piece in explaining why people age differently, and why cancer treatments fail in some patients.

Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.

Glioblastoma is notorious for late diagnosis, rapid progression, resistance to treatment and its biological complexity. A new experimental method could help detect this deadly type of brain cancer.

Prostate cancer screening compares favourably to screening for breast cancer in identifying significant cancers, reducing mortality and avoiding unnecessary harms, says new research.

A hidden immune circuit in the uterus revealed: Researchers have discovered a crucial immune switch that sheds light on preeclampsia and early pregnancy failure.

Researchers have discovered a new way to protect the heart during cancer chemotherapy without reducing antitumor efficacy. This could reduce long-term cardiovascular complications for patients.

A small but growing body of evidence suggests that a minimally invasive surgical procedure called lymphovenous anastomosis (LVA) might be an effective treatment for Alzheimer's disease.

Using machine learning, researchers have trained an electronic nose to detect early signs of ovarian cancer in the blood. The method could eventually be used to find many different cancers.

Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.

Less cancers missed, fewer complications: Mindfulness enables procedures to be done to a higher standard in awake patients than is currently possible under general anaesthesia or sedation.

Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.

Reseachers show how Candida albicans – a fungus living in our body – can make melanoma more aggressive. The results pave the way for antifungal therapies to complement skin cancer treatments.

Why do some tumours spread while others remain localised? Using colon cancer cells, scientists pinpointed the criteria that influence metastasis risk, and identified a way to assess its probability.

A new type of lab-grown organoid that mimics the behaviour of a human stomach could boost the understanding of rare gastric diseases, researchers say.

Non-specific symptoms such as fatigue, pain or weight loss can be caused by cancer, another serious condition or something completely harmless. A blood test can help provide relevant information.

The Kraft Center for Community Health has launched a new prize to recognise organisations using technology to transform healthcare access for underserved populations. At the 2025 World Medical Innovation Forum in Boston, ThriveLink – an AI-powered telephonic enrolment platform – was announced as the inaugural winner, receiving US $100,000 to further its mission of connecting families to vital…

A widely used chemotherapy drugs used in cancer treatments can cause heart damage, new research shows. This could be used to adapt treatment regimens - especially in patients with high blood pressure.

DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal cancer, research finds. This leads to better diagnostics and treatment.

A new study shows a significant survival benefit for patients with oropharyngeal cancers treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).

Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.

To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.

After T-cell redirecting therapies, patients are typically hospitalized for several days to watch for side effects. New research shows that these patients can safely be monitored at home.

A major new initiative aims to enable the development of advanced, specific and highly reproducible human in vitro models for greater understanding of disease and the acceleration of new medicines.

New hope for patients with neurological diseases: A combination of focused ultrasound and gene therapy enables targeted, nonsurgical control of seizure-relevant brain regions.

Just like the “ABCDE” mnemonic for melanoma awareness, researchers hope their diagnostic tool will transform how doctors approach persistent rashes, reminding them to consider lymphoma sooner.

Using a bioengineered bone marrow model, researchers were able to provide key new information on the efficacy and safety of CAR T-cell therapy for acute myeloid leukaemia (AML), the most common leukaemia in adults.

Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.

A biosensor that identifies volatile organic compounds (VOCs) in exhaled breath could be used in conjunction with AI to detect various thoracic cancers including lung cancer.

After a bout of influenza or Covid, the risk of heart attack or stroke may rise dramatically, and chronic infections may increase the long-term risk of serious cardiovascular disease events.

A novel imaging solution, called PSMA PET scanning, can more effectively detect the recurrence of prostate cancer compared to standard methods, and is associated with improved survival outcomes.

Chronic fatigue (ME/CFS) affects millions worldwide, but is poorly understood and has long lacked reliable diagnostic tools. Now, a new blood test claims to diagnose the condition with 96% accuracy.

Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.

Scientists have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body’s immune response.

Study of 3.7 million children reveals small but significant increased risk of blood cancers from medical imaging radiation, with CT scans posing highest risk

Using AI to help detect one of the leading killers of women worldwide: A new machine learning model can successfully predict heart disease risk in women by analysing mammograms.

A newly developed method to accurately quantify how much radiation is absorbed by the blood during cancer treatment could lead to more personalised, preventive, and safer radiotherapy.

An artificial heart valve made from SEBS, a new type of highly durable and biocompatible plastic, could be a step closer to use in humans, following a successful long-term safety test in animals.

The mere fact of being exposed to a sick avatar in a virtual reality environment triggers a measurable immune response in humans, a multidisciplinary research team discovered.

New research suggests that KFRE, a common prognostic tool to predict kidney failure, could underestimate the risk for individuals with chronic kidney disease (CKD) who also have frailty.

A multicenter study involving leading hospitals across Spain, has confirmed that people with COPD show altered levels of specific metabolites in their blood.

Do laboratory tests using blood-based biomarkers (BBB) represent the next type of universally recommended screening tests for Alzheimer's disease (AD)? Experts curb the high expectations for this type of diagnostic tool.

Tumor vesicles may serve as early indicators of cancer and help monitor the effectiveness of treatments. Now, researchers discovered a new way to detect these vesicles.

Classifying prostate cancer as “low-grade” could create a false sense of security and delay definitive treatments. A new study shows that the biopsy grade alone can paint an incomplete picture.

How cancer cells survive the journey through the body to form metastases is still poorly understood. New insights into how cells survive intense physical stress could pave the way for new treatments.

Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.

Laboratories across Europe are embracing sustainability through paperless workflows and automation. In this guest article, Gavin Hirst, Clinical Flow Cytometry Account Manager at Beckman Coulter Life Sciences, shares his thoughts on how digital transformation and eco-friendly practices not only advance climate goals but enhance efficiency, allowing scientists to focus on critical research rather…

At Medical Taiwan 2025, manufacturers attracted attendees with a wide range of innovations. We took a closer look at some of the most exciting companies and their products on display at the medical, health and care expo.

An implantable device could save diabetes patients from life-threatening hypoglycemia. Remaining under the skin, it can be triggered to release glucagon when blood sugar levels get too low.

Too many medicines, too many hospital visits: Inappropriate polypharmacy is a major driver of emergency hospital admissions among adults aged 65 and over, according to a new study.

A new technique called photoacoustic computed tomography (PACT) offers a breast imaging alternative without the discomfort, high costs, or risk associated with the conventional evaluation methods.

Molecular markers in saliva could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases, new research finds.

Molecular profiling of over 1,000 nasopharyngeal cancer (NPC) tumours reveals distinct differences in tumour microenvironment of locoregionally advanced NPC, supporting personalised treatment.

Should tracheobronchial anastomoses be routinely wrapped following resection and reconstruction? A new study revisits this unresolved question in airway surgery.

Newly developed technology can detect breast cancer relapses up to five years in advance. This advance could represent a turning point in post-treatment follow-up, the researchers hope.

A new ‘liquid biopsy’ test can help fast-track lung cancer patients to receive targeted therapy up to two weeks earlier, while helping avoid further tests and treatments including chemotherapy.

A US research team has shown that Sars-CoV-2 can “reprogram” pathogen-fighting white blood cells into immune system suppressing cells — a potential mechanism by which severe Covid may arise.

Does having blood type A increase the risk of breast cancer? A new systematic review and meta-analysis involving more than 13,000 breast cancer patients suggests a connection.

Using AI and extensive analyses of gene activity in tumours, researchers have found new, precise biomarkers to diagnose prostate cancer at an early stage through a simple urine sample.

A new approach enables the detection of even trace amounts of cancer cells. The method leverages SERS for signal amplification, eliminating the need for fluorescent dyes.

Molecular testing provides a more convenient, personalized way of monitoring of heart transplant recipients, according to insights shared at the Annual Meeting and Scientific Sessions of the ISHLT.

Using an advanced PET scanner, US radiologists explore how cancer, neurodegenerative diseases and other systemic conditions, can affect the brain by assessing the impact on the blood-brain barrier.

GPs may soon be able to identify patients with an increased risk of lung cancer up to 4 months earlier with an algorithm created by researchers based on the data of more than half a million patients.

Dr Ari Melnick has been appointed the new Director of the Josep Carreras Leukaemia Research Institute by the Board of Trustees. The institute specialises in biomedical research and precision medicine in the field of leukaemia and other hematologic malignancies.

Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.

Medical digital twins can help predict diseases, but are vulnerable to cyberattacks that can lead to incorrect diagnoses. Researchers have developed a new defense system to address this threat.

New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.

Soccer is not only a fun and popular sport, but can also help prevent many lifestyle-related conditions, including diabetes, heart disease, obesity, several cancers, and mental health challenges.

Losing weight is a great way to improve one's overall health. But, are these benefits gone once a person is gaining weight again? Not necessarily, a new study points out.

Engineers developed a robotic probe that can generate high-resolution 3D ultrasound images from deep inside the gastrointestinal tract. The robot reaches its target with a unique kind of movement.

Could a t-shirt with sensors reduce the time patients need to stay in hospital after a urological surgery? A recent pilot study suggests it might.

New findings show how AI-assisted mammography may not only reveal breast cancer, but can also assess calcium buildup in the arteries within breast tissue—an indicator of cardiovascular health.

For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.

The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.

A sensor, similar to glucose monitoring devices, detects lung cancer biomarkers from a blood sample in just 40 minutes. The technology has potential to identify at-risk patients and tailor treatments.

Researchers have clinically validated a previously developed urine test for prostate cancer screening, which can potentially bypass invasive procedures among men who are unlikely to benefit.

The immune system of children reacts differently to cancer than that of adults. New insights into these differences have the potential to lead to new tailored treatments for children with cancer.

A new deep learning model shows promise in detecting and segmenting lung tumors. The findings of the study could have important implications for lung cancer treatment.

A new personalised oncology platform has been tested to detect circulating tumour DNA (ctDNA) in patients with lung adenocarcinoma before surgery, to predict their risk of cancer relapse.

Light can change biological processes and affect health. For example, new research finds that red light can lower rates of blood clots that can cause heart attacks, lung damage and strokes.

A premiere that brings hope for fertility restoration to men who underwent chemotherapy during childhood: Researchers reintroduced cryopreserved immature testicular tissue taken 16 years prior.

Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.

A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.

More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the lungs such a tempting place for cancer cells? New research may have an answer.

Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.

Using a technique called field-cycling imaging (FCI) derived from MRI, researchers are able to detect signs of brain damage from stroke at ultra-low magnetic fields.

Treating patients with Hodgkin lymphoma with a different form of chemotherapy shows promise to reduce severe side effects, shorten hospital time and increase likelihood of recovering fertility.

New research has linked having a cerebral stroke to lasting changes in the arteries in the abdomen. The study in animal models with hypertension could lead to new preventative strategies.

New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.

Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.

Hyperbaric oxygen therapy (HBOT) treatments could offer relief to breast cancer patients who experience late toxicities following radiotherapy treatment. To date, the handful of completed clinical trials only produced inconclusive or contradictory results. Therefore, results from the latest trial, named HONEY (Effect of Hyperbaric Oxygen Therapy on Breast Cancer Patients with Late Radiation…

Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.

A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.

Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.

New research has revealed that the connection between PFAS, and kidney damage may be tied to dysregulation of the gut microbiome.

A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.

Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.

Kidney cancer is relatively rare, so dedicated screening programmes would not be cost-effective. Combined with lung cancer screening, however, this would be much more feasible, a new study shows.

Researchers have succeeded in identifying patterns of response to treatment in patients with multiple myeloma using AI tools, which helps to accurately predict the evolution of the tumor.

Before administering certain drugs, doctors check a patient’s kidney function by testing their blood urea nitrogen and creatinine levels. New research shows that gold nanoparticles might give more accurate results.

A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.

Researchers identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of patients lacking this blood group.

Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.

A new method of analysing the crystals in dehydrated blood could lead to a quicker, cheaper and less painful technique to diagnose, early detect, and monitor prostate cancer.

Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.

New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.

A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.

Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.

Dermatologists could benefit from a new algorithm that can help recognize patients with a highly aggressive form of basal cell carcinoma (BCC) of the face.

Researchers discovered islands of highly potent immune cells in the vicinity of glioblastomas. This may open up prospects for new therapies for these aggressive brain tumours.

Diagnosis and monitoring medical conditions, including cancer, diabetes, heart disease, and infections: In this opinion article, Alix Joseph (Linxens) explores the potential of sweat analysis.

Using genomic sequencing data, researchers have created personalised simulations of individual patients that can quantify the impact of genetic mutations on cancer cell behaviour.

A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.

Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.

Measuring temperatures in different face regions could be used to earlier detect chronic illnesses, such as diabetes and hypertension. Researchers now show the potential of an AI-based approach.

Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.

Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.

Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.

A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.

Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.

Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.

Scientists show that health registry data can be used to predict individual risks for the 20 most common cancer types. This could help to identify high-risk groups and enrol them for screenings.

Diagnosing lung conditions such as pulmonary embolism is more challengenging when a patient cannot tolerate contrast agents. Now, a new software solution is addressing the issue.

Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.

A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).

Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.

Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.

Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.

In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.

US researchers have developed and validated a new urine-based test for prostate cancer, which was shown to meaningfully reduce unnecessary prostate biopsies while providing highly accurate detection.

Beckman Coulter Diagnostics announced ahead of the ESCMID Global congress (formerly ECCMID) that it has extended the menu of DxI 9000 Immunoassay Analyzer* assays.

Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.

A team of Danish and Dutch researchers has combined an AI diagnostic tool with a mammographic texture model to improve the assessment of short- and long-term breast cancer risk. This new approach represents a significant step forward in refining the ability to predict the complexities of breast cancer risk.

Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.

A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.

How often should men get checked for their level of PSA, a marker for prostate cancer? A German study involving over 12,500 men shows that a five-year interval between tests is safe.

Papillary thyroid carcinoma (PTC) is often treated with surgical resection, which often comes with significant side effects. Now, a new study points to a minimally invasive alternative.

Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.

Atrial fibrillation is the most common heart rhythm disorder globally. Patients at high risk for AF, such as those with heart failure or prior stroke, should be tested at every GP visit, experts say.

US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.

Pulse oximeters delivering poorer results in people with darker skin tones, underdiagnosis of cardiac conditions in women: some medical devices are not as fair as the ought to be, a new review finds.

A team of researchers has discovered a new method of measuring levels of cortisol directly from a blood sample - a significant step forward in diagnosis and treatment of a wide range of diseases.

Researchers have found a surprising method to reduce blood glucose levels in a person: Shining red light on their back. This could help control diabetes without medication.

An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.

Chronic stress can have a significant impact on health, from an increased risk for heart disease to a greater susceptibility of cancer metastasis. New research points out the underlying mechanisms.

Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.

Researchers in Singapore have developed an AI-based software to assist in the early detection of breast cancer. Using thermal imaging, the program assesses the malignancy of a tumour.

Chemotherapy can be toxic to heart cells. To help protect the hearts of cancer patients, Cedars-Sinai investigators have created a three-dimensional “heart-on-a-chip” to evaluate drug safety.

Academic labs and biotech firms pioneer multi-cancer early detection with emerging technologies. Screening for multiple cancers with a simple blood or urinary draw could be a game-changer. Two research teams in particular have advanced the field.

A simple blood test could help diagnose patients with glioblastoma, the deadliest form of brain cancer, sparing them from undergoing invasive and highly-risky surgery, report UK researchers.

As a result from better living standards and medical advances, population longevity increases – a development which, paradoxically, current healthcare systems are ill-prepared for, Sir John Bell points out. The UK’s Our Future Health programme, which he chairs, exemplifies the paradigm shift to a prevention-centered healthcare approach.

AI models are highly capable in analysing tissue samples – as long as conditions are lab-perfect. Add a little contamination, however, and diagnostic accuracy goes out the window, a new study shows.

Canon Medical Systems Corporation and Olympus Corporation announced that they have reached an agreement to collaborate on Endoscopic Ultrasound Systems, and presented a new imaging system.

Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.

Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.

An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.

It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.

US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.

Researchers and clinicians at Washington University in St. Louis found a way to improve diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes.

White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.

University of Waterloo researchers are pioneering a method to detect breast cancer in women early enough for them to receive life-saving treatment.

Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…

Using small blood vessels grown in the lab, researchers discover how vascular leaks leading to dementia and stroke emerge – and how this damage might be fixed.

A nationwide programme to reduce the risk of developing diabetes in the United Kingdom is proven beyond reasonable doubt to work, a new study reveals.

Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.

A multinational study confirms a strong and clear association between exposure to radiation from CT scans in young people and an increased risk of blood cancers.

A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.

Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.

Philips and Quibim have signed a multi-year agreement to work on an integrated solution including an AI-based software to automate real-time prostate gland segmentation in MR images.

University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.

A new class of antibiotics, based on proven drugs used in cancer treatment, is now being developed by researchers at Linköping University. They could be used against resistant bacteria.

A team from UNC has developed a steerable lung robot that can autonomously maneuver the intricacies of the lung, while avoiding important lung structures.

Engineers from MIT are developing a device containing insulin-producing cells and a tiny oxygen-producing factory to keep the cells of diabetes patients healthy.

From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.

Basque researchers propose a bioelectronic device consisting of gold electrodes coated with a smart polymer capable of capturing and releasing cells in a non-invasive, controllable way.

Cancer has become strikingly more common in people under 50 in the past three decades, an international research team finds. The reseachers explore what this means for future death tolls.

New research from Lund University has found a suprisingly high incidence of sepsis across hospital admissions. The experts say that the condition can be likened to an epidemic.

Can per- and polyfluoroalkyl substances (PFAS) increase the risk of breast cancer? A new study by US researchers examines the effects of the so-called “forever chemicals”.

Using data from more than 400,000 individuals, researchers have created a platform for predicting the risk of developing blood cancers such as acute myeloid leukaemia over a 10-15-year period.

Patients with immunodeficiency cannot benefit from conventional Covid-19 vaccines and still at risk from infection. A promising new approach now brings hope for this patient group.

While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.

With the recent recommendation changes from the European Council in 2022, how radiologists screen for breast cancer is changing. Mammography has long been an essential technology in screening for breast cancer, and in the recommendations the Council formally recognized the advantages of digital breast tomosynthesis (DBT). This landmark acknowledges the research on and benefits of DBT, advocating…

Combining ultrasound and MRI technology can help detect prostate cancer at an earlier stage and potentially save lives, according to new University of Dundee research.

Plastics are a part of everyday life, and an increasingly concerning factor of global environmental pollution. They also have infiltrated our bodies as microparticles (MPs) and nanoparticles (NPs), found even in placentas supporting foetal life. And they are in our blood. Now, researchers in Spain have developed a new method to detect and measure nanoparticles in human peripheral blood that is…

Research by the University of Southampton has shown that repeated Covid-19 vaccination increases the ability of lymphoma patients to prevent infection from the virus, particularly after four doses.

Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…

French scientists discovered that CD4 T cells generated during immunotherapy are capable of remotely neutralizing tumor cells by producing interferon gamma (IFN-γ).

New research suggests that combining blood biomarkers with genomic information more accurately, cost-effectively predicts the risk of developing diseases.

A trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms.

AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.

Scientists from the University of Edinburgh have found that the accuracy of detecting bowel cancer is increased to almost 100% by carrying out a common test twice rather than once.

A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.

Women with triple-negative breast cancer who received multiple antibiotic prescriptions within three years after their cancer diagnosis were more likely to experience disease recurrence and to die from their cancer.

Researchers at the University of Campinas and the Federal University of São Carlos in Brazil have developed an electrochemical sensor that detects Parkinson's disease at different stages.

An international coalition of biomedical researchers has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

A new real-time imaging technique that uses a type of infrared light has, for the first time, been used during surgery to differentiate between cancerous tumours and healthy tissue.

A team of scientists has successfully generated genetically defined mouse models for two subtypes of multiple myeloma. This will contribute to a better understanding of how the disease develops in humans.

Testing for genetic mutations in urine can detect bladder cancer years before the disease shows clinical symptoms, new research has shown - reaching more than a decade for the most common cancer type.

Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).

Using imaging guidance, interventional radiology – a sub-discipline of diagnostic imaging – allows targeted and ultraprecise diagnostic and therapeutic procedures without anesthesia and without large incisions. Nevertheless, surgery continues to be widely considered the procedure of choice, making interventional radiology the Cinderella of the discipline. Professor Dr. Marco Das, Medical…

Researchers at the University of New South Wales unveil prototype device that can directly 3D print living cells onto internal organs and potentially be used as an all-in-one endoscopic surgical tool.

Exposure to a mixture of chemicals called PFAS - also known as 'forever chemicals' - leads to alterations in biological processes associated with a broad range of diseases, a new study finds.

A new study confirms that haematopoietic stem cell transplantation can be used to cure patients with HIV infections. This third successful case gives new insights into the underlying processes.

Scientists are developing a new kind of light-activated cancer treatments. This would work by switching on LED lights embedded close to a tumour, which would then activate biotherapeutic drugs.

Researchers have developed a new blood test to detect prostate cancer which displays greater accuracy than the current prostate-specific antigen (PSA) method.

Carriers of a specific bacteria have a 14% chance of developing an antibiotic resistant infection with 30 days of hospitalisation, according to new research from Amsterdam.

The distinction between primary tumors and metastases can be made quickly and accurately in brain tumors using radiomics and deep learning algorithms, a new study shows.

Canadian researchers are developing a new, ultra-sensitive biosensor to screen for Alzheimer’s disease and other diseases. The device has successfully completed the proof-of-concept stage.

Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.

Dutch physicians have developed a system to determine the right dose of immunosuppressive drugs for patients to receive a donor liver - to prevent the activation of the Epstein-Barr virus.

Dutch scientists have discovered how specialized immune cells can detect and remove cancers that are ‘invisible’ to the conventional defense mechanisms of the immune system.

Researchers generated human mini bones in the lab which mirror the composition and function of human bone - a step toward the development of future patient-tailored models of bone cancers and tumors.

Scientists have discovered a way to train healthy immune cells to acquire the skills of some tumor cells for a good purpose: to accelerate diabetic wound healing.

Treating pancreatic cancer patients with chemotherapy before surgery significantly improved 1-year survival rates compared to immediate surgery, a randomised clinical trial has found.

An international study shows that a new method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods.

Scientists from Singapore discovered a novel low-cost method of testing for cancers. The test sequences heated clinical samples to isolate cancer-specific signatures found in a patient’s blood.

Canadian researchers have developed a new method of killing brain cancer cells while preserving the tissue around it. A remarkable side-benefit: chemotherapy of the cancer suddenly becomes possible.

In surgery, artificial intelligence (AI) is applied mostly in imaging, navigation, and robotic intervention. However, AI can also play a major role in preoperative planning. Objective decisions-making, optimal utilisation of operating theatres and less overtime are additional advantages that are achieved with the use of AI in surgery.

One robot supports the surgeon’s control of tiny instruments, while another automatically keeps an eye on what is happening: With this novel combination, surgeons in Münster have successfully performed fully robot-assisted microsurgery for the first time. Presenting the new procedure at the Hornheide Specialist Clinic, the experts explain how the interaction of both robotic systems ensures…

It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.

Innovative smart weighing scales are adding a new dimension to home monitoring for healthcare. By collecting data via sensors and proprietary technology as people stand on them, the scales can assess health metrics to give users more precise measurements for a deeper understanding of their body.

New tests can identify over 50 types of cancer and boost detection of traditionally elusive cancers from tumour DNA in blood, researchers showed at the ESMO congress in September. These multi-cancer early detection (MCED) tests in development can spot common cancer signals and predict where the signal comes from in the body, results from a prospective investigation suggest.

A collaborative study has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukaemia (CLL), and associated these with clinical outcomes.

White matter hyperintensities (WMH) on the brain seen on MRI represent a biomarker associated with a 50/50 risk of death within five years after a first incident acute ischemic stroke (AIS) or transient ischemic attack (TIA).

The risk of developing breast cancer is higher in breasts with high density. But why is that? Researchers at Linköping University have shown major biological differences that promote cancer growth.

99mTc-Sestamibi SPECT/CT can aid in the diagnosis of solid renal lesions, especially in cases where contrast enhanced CT findings are inconclusive, according to researchers from the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis, Missouri.

With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.

Some leukemias evade treatment by changing their appearance and identity through changing the read-out of their DNA, a new study has found.

Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.

A simple 'liquid biopsy' blood test could help guide the treatment of children with the cancer rhabdomyosarcoma, a new study reports.

It’s widely known that more than 70% of today’s medical decisions involve the results of laboratory tests, but the insights clinicians derive from these tests today may only be scratching the surface of their potential.

Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.

A new device for diagnosing bone fragility invented by the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE) has been approved for marketing in the European Economic Area and Switzerland. The device is based on a new approach to assessing bone quality via blood sampling.

The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team now showed that EVI1's cancer causing effect relies on activating a single gene — the stem cell transcription factor ERG.

The hearts of men and women are different – while this insight has been established for quite some time now, it might even surprise cardiologists just how deep these differences really run. In her presentation at this year’s ESC, Diana Bonderman, MD, gave a comprehensive roundup on sex differences in risk factors and subtypes of heart failure.

A new study led by researchers in Barcelona has determined the protein TIMP-1 as a valuable biomarker for the progression of lung adenocarcinoma. The results open the door to new treatments.

Researchers from the University of Bern and Inselspital provide an overview of the latest technologies in precision oncology. Translating these into clinical application is still a major challenge.

Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.

With the life expectancy of populations improving, experts believe the rising diagnosis and prevalence of patients with heart failure with preserved ejection fraction (HFpEF) will have a significant impact on healthcare services going forward.