A new type of peptide receptor radionuclide therapy (PRRT) appears to be safe in metastatic neuroendocrine tumor patients who have exhausted conventional treatment options.
A compact LED module pairs UV-A, green and IR light with a matched photodiode to detect AGE autofluorescence — bringing biochemical risk screening to wearables and point of care testing.
A sample of inequality: A new study shows that AI models can infer demographic information from pathology slides, leading to bias in cancer diagnosis among different populations.
Hospitalists face a dual challenge when a critically ill pregnant patient is admitted to a hospital: providing safe and effective treatment for both mother and fetus. At the annual meeting of the Society of Hospital Medicine (SHM) in Las Vegas, an expert discussed why hospitalists must draw on a variety of skills when treating pregnant inpatients.
A new PET imaging technique can accurately detect and monitor Mycobacteroides abscessus lung infections—one of the most difficult-to-diagnose conditions in patients with lung diseases.
New research makes a strong case for a new dual-targeting radiopharmaceutical, designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy.
Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.
Artificial Intelligence (AI) remains a divisive topic within the discipline of pathology with a range of opinions over its current value and applicability in clinical settings. While most experts agree that the technology will not replace pathologists, it might still spell bad news for those who do not embrace AI in their daily practice. On the other hand, reservations persist about whether…
Before administering certain drugs, doctors check a patient’s kidney function by testing their blood urea nitrogen and creatinine levels. New research shows that gold nanoparticles might give more accurate results.
Ultrasound plays a pivotal role in the assessment of organ transplant patients. It enables physicians to safely and easily assess progress, identify complications and resolve problems, as well as deliver long-term monitoring. The value of ultrasound in the transplant space was highlighted in a session at ECR 2024, covering liver, renal, pancreas, paediatric and multi-organ transplants with…
New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.
A prospective study has revealed that kidney dysfunction may be a powerful predictor of sudden cardiac death. Findings could lead to revisions in the guidelines for ICD usage.
Metabolic disorders, renal failure, UTIs, sepsis, poisoning: The higher temperatures climb in summer, the more people are hospitalized, a study shows - with some groups being more at risk than others.
A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).
Striking the balance between diagnostic efficacy and patient safety remains critical when utilising iodinated contrast media to deliver the best imaging outcomes. While playing a crucial role in diagnosis and treatment of disease, CT expert Efthimios Agadakos believes the medical profession has a duty to do its utmost to minimize patient risk from contrast media.
Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.
A Korean research team has advanced the imaging of kidney diseases using ultrafast ultrasound that captures 1,000 images in just one second.
University of Ottawa scientists have introduced a metal-free MRI dye capable of mapping kidney function with unprecedented accuracy — a promising technique for more personalized care.
A new PET tracer, 89Zr-DFO-girentuximab, can accurately detect a type of kidney cancer called clear cell renal cell carcinoma and differentiate it from other types of kidney tumors.
A team of scientists has successfully generated genetically defined mouse models for two subtypes of multiple myeloma. This will contribute to a better understanding of how the disease develops in humans.
In a world first, scientists from Singapore and Germany have shown that regenerative therapy to restore impaired kidney function may soon be a possibility.
Dutch physicians have developed a system to determine the right dose of immunosuppressive drugs for patients to receive a donor liver - to prevent the activation of the Epstein-Barr virus.
99mTc-Sestamibi SPECT/CT can aid in the diagnosis of solid renal lesions, especially in cases where contrast enhanced CT findings are inconclusive, according to researchers from the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis, Missouri.
Despite treatment, chronic lung diseases such as COPD or cystic fibrosis can become so severe that a lung transplant is necessary. Dr Urte Sommerwerck explains which patients might be considered for transplantation and why follow-up is as important as the surgery itself.
Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…
Clinical laboratories need to be proactive to attract transgender patients for testing and to ensure that they are comfortable with the services provided. This issue is of great importance to the American Association for Clinical Chemistry (AACC), which conducted a scientific session on transgender health at its recent annual meeting in Chicago.
A team from Geneva has discovered a molecule that can identify the development of diabetes before the first symptoms appear.
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
Researchers in Sweden have now discovered a faster and easier way to determine who has an aggressive form of prostate cancer, and who has not.
Rapid technical advances in ultrasound and increasingly tight healthcare budgets call for a change in ultrasound practice, experts explained in a session at the ECR in Vienna. Two experts presented possible models for the next two decades.
Researchers have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.
Advances in image post-processing and contrast-enhanced techniques have widened the scope of possibilities for MRI and ultrasound vascular imaging, experts showed in a dedicated course at the ECR Overture.
Finding the right antibiotic dose is akin to a Goldilocks problem: give too little, and the infection will persist; too much, and side-effects will override the benefits of the therapy. To get it “just right”, Prof Dr Birgit Koch talks about dosing optimisation in the clinical setting.
MediSCAPE, a high-speed 3D microscope, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments.
To provide a solution for the challenges of the coronavirus pandemic, Beckman Coulter recently launched the DxU Iris, a urinalysis solution which aims to improve lab workflows.
Reducing inflammatory mediators in the blood before surgical treatment of cardiac bacterial infection does not improve clinically relevant outcome, a new study shows.
Digital technology solutions create new opportunities in diagnosis and assessment of renal conditions. With whole slide imaging (WSI), improved workflow and better visualization, such technology already yields a ROI for hospitals and laboratories.
Researchers have leveraged the power of digital pathology and computational modeling to detect and quantify podocytes, a specialized type of cell in the kidney that undergoes damaging changes during early-stage kidney disease.
A study found that women who contract Covid-19 during pregnancy are at significantly higher risk of developing pre-eclampsia. In their study, researchers said their systematic review shows that women with SARS-CoV-2 infection during pregnancy had 62% higher odds of developing preeclampsia than those without the infection during pregnancy.
A nationwide US study has shown that the rate of opioid-related cardiac arrests has steeply risen and is now on par with the rate of cardiac arrest from other causes. The research is presented at ESC Congress 2021. Opioid use disorder, which includes dependence and addiction, affects more than two million people in the US, while opioid overdose is the leading cause of death for those aged 25 to…
Over recent years interventional oncology (IO), as a subspecialty of interventional radiology, has become a standard component of many cancer therapies. The broad range of minimally invasive methods – and their results – are often comparable to those of traditional approaches, such as surgery, chemotherapy or radiotherapy, e.g. with regard to hepatocellular cancer (HCC), oligometastatic…
Interdisciplinary team from Washington University School of Medicine in St. Louis and the university’s McKelvey School of Engineering finds better way to design clot-prone grafts currently used for dialysis.
Specialist biorepositories are helping advance personalised medicine by supporting the availability of human tissue for research using digital pathology techniques. The pivotal role of the Glasgow Tissue Research Facility (GTRF) in making tissue available to shape new therapies and treatments was outlined in a presentation to the online “Transforming Digital Pathology – Integrating AI to Move…
A new research project will embrace the combination of 5G telecommunications technology and AI to offer continuous remote monitoring to seriously ill heart failure patients, for example those with Left Ventricular Assist Devices (LVADs).
Magnetic resonance imaging (MRI) is widely used to identify the narrowing or blockage of blood vessels. Contrast agents improve the visibility of the structures and offer more accurate information of vascular conditions such as vascular blockage and stenosis. Commonly used gadolinium-based contrast agents must be administered in chelated forms due to the gadolinium ions' high toxicity and pose…
Whole-body magnetic resonance imaging (WB-MRI) can detect prostate cancer and inform about treatment response and disease progression earlier and better than other imaging modalities. A Belgian expert will delve into the latest and future developments of the technique for prostate cancer and distant metastases imaging in a dedicated session at ECR. WB‐MRI and nuclear medicine -…
This July, Fujifilm Sonosite launched Sonosite PX, its newest ultrasound system, in the midst of the Covid-19 pandemic. Diku Mandavia, M.D., Chief Medical Officer of Fujifilm Sonosite, sat down with sonographer and Sonosite’s Director of Marketing Development Jodi Miller to discuss how Sonosite’s newest ultrasound system can help frontline health care workers combat the pandemic and why…
Spatial analytics offers greater clarity in the assessment of tumours beyond routine microscopic analysis. High-capacity digital image analysis enables new methods of spatial statistics to extract features not immediately distinguishable by visual inspection. These subvisual features reflect complex properties, such as intratumour heterogeneity and have the additional benefit that they can target…
40 years ago, anticipating the huge impact of computers in radiology, a group of visionaries formed the Radiology Information System Consortium (RISC). In 1989, RISC created the Society for Computer Applications (SCAR) to promote computer applications in digital imaging. Those organisations became the Society for Imaging Informatics in Medicine (SIIM). At SIIM 2020, a virtual meeting, experts…
To investigate rare diseases, applying image-based analytics approaches, including the use of deep learning convolutional neural networks (DL-CNNs), can be a major challenge due to great difficulties in acquiring sufficient numbers of cases and associated digital image sets from the small cohorts typically available. To realise algorithms that are both effective and generalisable, conventional…
Due to the scientific and technical developments in recombinant DNA technology and protein engineering since the early 1980s, therapeutic proteins have emerged as one of the most important classes of new pharmaceuticals. Currently, more than 200 protein and peptide based drugs have gained approval by the USA’s Food and Drug Administration (FDA) and many more are under preclinical or clinical…
Whole-body magnetic resonance imaging (WB-MRI) is championed as offering significant benefits, such as improving disease evaluation for prostate cancer patients. During an intense session in genito-urinary cancer at ECR 2019, three key speakers focused on the advantages over conventional imaging modalities as well as discussing new PET (Positron Emission Tomography) tracers.
The Nobel Assembly at Karolinska Institutet has today decided to award the 2019 Nobel Prize in Physiology or Medicine jointly to William G. Kaelin Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza for their discoveries of how cells sense and adapt to oxygen availability.
Amid ever-growing demand for services, significant challenges face the pathology workforce in the years ahead but – there are also good opportunities. With advances in technology and the advent of artificial intelligence as a decision-making support tool, Professor Jo Martin, President Royal College of Pathologists (RCPath) in the UK, believes there remain opportunities for pathology to play a…
Point-of-care ultrasound (POCUS) systems are becoming a common sight in nephrology departments and renal dialysis clinics, helping clinical staff to evaluate and effectively access the vasculature of dialysis patients. Dr Jean-Yves Bosc, a nephrologist and vascular doctor working at the non-profit private health establishment AIDER SANTÉ in the South of France, has been a champion of ultrasound…
The latest study by the German Society for Haematology and Oncology (DGHO), ‘Prognosis for population-based morbidity for common cancers in Germany – impact on provision’ has made it clear that due to demographic developments in Germany and to medical advances in oncology, the requirements for cancer patients’ care are ever more diverse. The increase in newly diagnosed cancer patients is…
Pathologic-radiologic correlation is already utilised in various settings as a tool to assess the interpretive performance of imaging studies and identify radiologic features corresponding to histologic findings. However, correlative assessment is currently limited mainly to the fields of research and quality assurance, and is generally not a routine element of the radiologist or pathologist…
Researchers identified how to kill therapy-resistant cells in hypoxic tumors and in cells arising in the von Hippel-Lindau hereditary cancer. In a recent publication in PNAS, the research group identified how to kill therapy-resistant cells in hypoxic tumors and in cells arising in the von Hippel-Lindau (VHL) hereditary cancer.
Women with pre-eclampsia during pregnancy have a five-fold increased risk of end stage kidney disease (ESKD) later in life compared to women who don’t develop pre-eclampsia during pregnancy, according to a new study. Professor Louise Kenny from the University of Liverpool is one of the co-authors of the study, which is published in PLOS Medicine and also involved researchers at University…
For patients with kidney failure who need dialysis, removing fluid at the correct rate and stopping at the right time is critical. This typically requires guessing how much water to remove and carefully monitoring the patient for sudden drops in blood pressure. Currently there is no reliable, easy way to measure hydration levels in these patients, who number around half a million in the United…
For patients with Type 1 diabetes who don’t respond well to insulin or have other serious medical complications caused by their disease, pancreas transplantation offers hope for a cure. But obese candidates who need a pancreas transplant often are denied the procedure because of poor outcomes, including high rates of incision infections, which are linked to an increased risk for failure and…
The pros and cons of CT (computed tomography), MRI (magnetic resonance imaging) and CEUS (contrast enhanced ultrasound) for emergency abdominal use were highlighted by speakers in an ECR 2019 session under the broader heading: ‘Abdominal Emergencies: advanced imaging in daily routine’.
Image analysis of prostate cancer is a challenging area for clinicians. The disease shows a low mutation burden compared to melanoma and stomach cancer, for example, making morpho-molecular correlation more difficult, and there is often very low inflammation. With the role of tumour infiltrating lymphocytes in prostate cancer currently unclear – and with the advent of new approaches to prostate…
People with untreated White Coat Hypertension are twice as likely to die from heart disease. Researchers at Penn Medicine say findings underscore the need for increased out-of-office blood pressure monitoring
In October 2016, Xenios became a part of Fresenius Medical Care (FME), the world’s leading provider of products and services for people with chronic kidney failure. The integration of the expertise from FME and Xenios and thus the combination of the companies’ competences strongly enhances treatment options in critical care within the intensive care unit (ICU) of hospitals across the world.…
The U.S. Food and Drug Administration (FDA) approved Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) capsules for the treatment of the heart disease (cardiomyopathy) caused by transthyretin mediated amyloidosis (ATTR-CM) in adults. These are the first FDA-approved treatments for ATTR-CM. Vyndaqel and Vyndamax have the same active moiety, tafamidis, but they are not substitutable on a…
Radiologists have not ended talk about artificial intelligence and machine learning but, rather than fear for the future of their profession, they themselves must decide how that should be, an eminent expert Dr Woojin Kim warned ECR delegates in Vienna in March. Two years in discussion and the hype around artificial intelligence (AI) is far from fading. Interest has never been higher, and the…
A one-off operation that targets the nerves connected to the kidney has been found to maintain reduced blood pressure in hypertension patients for at least six months, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research (NIHR). The study, published in the journal…
In patients with kidney failure, influenza-like illness (ILI) likely contributes to more than 1,000 deaths per year. The finding, which comes from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN), points to the importance of protection against, surveillance of, and, where possible, treatment of such infections in patients with kidney dysfunction.…
New data reveals the life expectancy of patients with kidney cancer that’s traveled to the brain has now stretched from months to years. UT Southwestern Kidney Cancer Program investigators report survival rates beyond 2.5 years for some patients with specialized multidisciplinary care. Historically, patients whose kidney cancer had spread to the brain were believed to have only about six months…
New 7-Tesla MR methods could potentially shed light on cardiomyopathies’ principles, according to a leading French radiologist who also stresses the importance of teamwork between radiologists, cardiologists, surgeons and anaesthesiologists. Morphologic and dynamic information of the myocardium is achieved with millimetric resolution (0.9x0.9 square mm). Strong intensity variations…
Confirming or infirming hypotheses has long driven scientific research; however, this traditional and costly approach is giving way to data-driven initiatives, according to Prof. Laure Fournier, a leading radiologist at Georges Pompidou European Hospital in Paris. “Usually we formulate the hypothesis first, then take an image and analyze it. We like that in France, it comes from Descartes. The…
New products and technologies in medical practice expect the specialists of the leading international exhibition Bulmedica/Buldental from 16 to 18 May at Inter Expo Center. This year, the medical profile of the exhibition will focus on the progress in imaging, physiotherapy, aesthetic medicine. Once again Bulmedica/Buldental will be a platform to keep an eye on the tendencies, a meeting point of…
Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease (CKD) will need to undergo a kidney transplant or start receiving dialysis. Although this type of prognostic guide exists for adults, this is the first such tool specific to children. “We designed a clinically useful, data-driven…
Steps taken by a New York health system to identify and tackle acute kidney injury (AKI) at an early stage are having a significant impact on improving intervention and patient outcomes. Key to the turnaround has lay in pathologists accessing big data from the laboratory, and working more closely with administrative personnel to identify early AKI and then responding to it more quickly. Speaking…
The recent ACC/AHA Guidelines have increased the number of patients said to have hypertension by up to 40 percent (new 130/80 mmHg). The international recommendation is to treat hypertension with angiotensin converting enzyme inhibitors (ACEIs). These drugs, however, have significant adverse effects: Often a chronic dry cough leads to patients withdrawing from treatment. On rare occasions, ACEIs…
With immunotherapy, bigger lesions may be spotted on CT, but it doesn’t necessarily mean that the disease is progressing. As treatment works, it can cause what has become known as pseudo disease progression; and this is just one of the many revolutions immunotherapy is triggering in oncology imaging, Professor Clarisse Dromain (Lausanne/CH) explained as she opened the session dedicated to this…
Radiologists must ensure precise scientific data and radiology-based evidence are used to regulate the use of Gadolinium Containing Contrast Agents (GCCAs), a Spanish leading radiologist explained in closed-door leadership meeting earlier this year in Barcelona.
NIH-supported researchers at Massachusetts General Hospital (MGH) are studying an alternative to the contrast agents currently used for magnetic resonance imaging. In a recent study, they showed that the experimental alternative, a manganese-based compound, performs as well as approved contrast agents. Their study appeared online in Radiology. Magnetic resonance (MR) images are taken so that a…
Professor Jo Martin, the newly-appointed President of the Royal College of Pathologists in the United Kingdom, believes the National Health Service (NHS) is on the brink of embracing digital pathology more widely. A number of UK laboratories, he explained, are adopting digital pathology in histopathology – in line with some labs in Sweden and Holland, where it has become routine – and the…
Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone. The study already spurred a clinical trial in ovarian cancer patients. The…
A clinical trial involving hundreds of participants has shown that one of the most frequently prescribed antidepressants may not benefit millions of patients who also have chronic kidney disease (CKD). “These results provide evidence that could change clinical practice,” said Dr. Susan Hedayati, Professor of Internal Medicine at UT Southwestern and first author of the study, which was…
Overcrowding in healthcare systems has become a worldwide phenomenon with regional influences related to the different healthcare structures in different countries. A recent BBC analysis (February 2017) showed that overcrowding afflicted 9 out of 10 NHS hospitals this winter, with 23 declaring ‘black alerts’, as other European hospitals face similar ‘care crises’, especially member states…
A Spanish team has, for the first time, successfully placed a pulmonary valve using catheterisation through the hepatic vein in a paediatric patient. Specialists believe this type of intervention could become an interesting alternative when traditional access points are not available.
Every cancer is different and every patient is different. This insight gained in personalised medicine prompted oncology researchers to focus more on the individual patient’s immune system. It is particularly the immune system’s ability to destroy cancer cells that raised hope.
Gadolinium-based contrast agents are an essential component of MRI exams, but are challenged by findings of residual depositions of gadolinium in the body, even though the clinical relevance remains unknown. Three clinicians described how changes to MRI protocols and dose levels for contrast media can optimise the balance between benefit and risk for patients and radiologists.
A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.
Bracco Imaging S.p.A., a global leading company in the diagnostic imaging business, today announced the approval of the use of MultiHance® (gadobenate dimeglumine) in Magnetic Resonance Imaging (MRI) of the whole body in adults and paediatric patients (> 2 years). The approval was obtained through a Mutual Recognition Procedure, with the Medicines and Healthcare products Regulatory Agency…
An innovative cardiac monitoring system that delivers continuous resynchronisation to patients, has shown a 35% risk reduction of hospitalisation for heart failure (HF) patients. The finding comes from the RESPOND-CRT (cardiac resynchronisation therapy) clinical trial, which was designed to investigate the clinical efficacy and safety of device-based optimisation using the SonR cardiac…
The prostate remains the only organ where random biopsies are performed to find cancer, notes Jean-Michel Correas MD PhD, from the Necker University Hospital in Paris. If we proposed this approach to a woman to search for breast cancer, it would be outrageous, he said.
‘In imaging there is a trend towards quantification,’ said Professor Siegfried Trattnig, Medical Director of the High-Field MR Centre (HFMRC) at the Medical University Vienna, Austria. Whilst before, radiologists’ findings were subjective, qualitative results, based on signal intensity and grey scale, he pointed out. ‘Today imaging can draw on quantifiable and comparable parameters with…
Living in a small Mediterranean island has its own advantages; nevertheless there are certain limitations. In healthcare, for example, resources may be somewhat more limited in such a small country and some of the latest technologies may not always be available to patients.
The radiology department at the German hospital Asklepios-Klinik Lindau recently received the high-performance R/F table Sonialvision G4, a new generation of X-ray and fluoroscopy systems, which complements examination and therapy options, particularly in internal medicine, as well as general surgery and for spinal disorders, the manufacturer Shimadzu reports.
Since 2012, at least 1,500 individuals have developed Middle East respiratory syndrome (MERS), resulting in more than 500 fatalities. Only now are results being reported of the first autopsy of a MERS patient, which was performed in 2014. Not only do these findings, published in The American Journal of Pathology, provide unprecedented, clinically-relevant insights about how MERS progresses, they…
Building on an innovative ultrasound technology that continues to yield break-through capabilities, SuperSonic Imagine is introducing AngioPLUS, a third diagnostic functionality for its Aixplorer platform that promises to be instrumental in the diagnosis of cancerous tissues as well as musculoskeletal pathologies.
Findings demonstrate that testosterone is a metabolic hormone as well as a sex hormone, University at Buffalo researchers say.
Leading Spanish experts presented the latest developments in hepatitis C management in their country during the May meeting of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) in Seville. Report: Mélisande Rouger
University of Virginia School of Medicine researchers have discovered a new strategy for attacking cancer cells that could fundamentally alter the way doctors treat and prevent the deadly disease. By more selectively targeting cancer cells, this method offers a strategy to reduce the length of and physical toll associated with current treatments.
40 years after the launch of its first series model, Siretom, Siemens Healthcare is looking back on the successful development of its computed tomography division. With innovations such as Spiral, Multislice, and most recently Dual Source technology, Siemens has been driving the CT market and clinical diagnostics for decades. Today, three patients are scanned with a Siemens CT system every…
It’s thumbs up for Siemens Healthcare Diagnostics’ Aptio Automation, following a two-year deployment by Dundee-based National Health Service (NHS) Dundee, the first north European healthcare organisation to use the system to consolidate formerly siloed biochemistry, immunology, haematology and haemostasis testing onto a single automation track.
Iron deficiency and resulting anaemia cause fatal comorbidities worldwide. Despite this, they are generally underestimated. Professor Lothar Thomas, specialist in laboratory medicine at the Central Laboratory in the Frankfurt/Main University Hospital, is seeking more information about new laboratory parameters for diagnosis and monitoring of iron deficiency and iron substitution therapy. The…
For medical ultrasound it’s quick, easy and portable – and so popular with Professor Christoph Dietrich, chief of Medical Department 2 at Caritas Hospital, Bad Mergentheim, one of the first physicians worldwide to test the M9 in clinical routine. ‘The compact Mindray colour Doppler system is about the same size as a notebook computer. The imaging suite comes to the patient,’ the…
The very first successful organ donation from a newborn to be carried out in the UK is reported in the Fetal & Neonatal Edition of Archives of Disease in Childhood. The donor was a girl born at term after an emergency caesarean section in the neonatal unit of Hammersmith Hospital, London. The donation involved the kidneys, which were transplanted into a patient with renal failure, and liver…
Iron deficiency and resulting anaemia cause fatal comorbidities worldwide. Despite this, they are generally underestimated. Professor Lothar Thomas, specialist in laboratory medicine at Central Laboratory of the University Hospital of Frankfurt/Main, is calling for more information about the new laboratory parameters for diagnosis and monitoring of iron deficiency and iron substitution therapy.
Radiotherapy is being proposed to treat heart diseases, specifically for hypertension and atrial fibrillation (AF).
Postoperative infections after knee or hip joint replacements are among the most feared complications in orthopaedic surgery. At the EFORT Congress in London current research was presented that provides new insights in this field: Fracture patients are especially vulnerable to infection. New biomarkers should improve early diagnosis of risky infections.
It was the quiet before the storm. At the end of March, during the American College of Cardiology (ACC) meeting in Washington, the future of renal denervation was about to be decided with the presentation of the Medtronic-funded Simplicity HTN-3 clinical trial.
As well as this year’s programme being the biggest yet, with 76 plenary sessions, there are also sponsored symposia from Janssen and CamNutra. Additionally, the USA’s Mayo Clinic will provide the Cardiology Review Course, with representatives from Rochester, Minnesota, delivering some sessions.
It is the quiet before the storm. At the end of March, the future of renal denevation will be decided with the presentation of the Simplicity HTN-3 clinical trial at the American College of Cardiology meeting in Washington.
There is a wealth of information in every radiology exam, but even a phalanx of super-computers at the National Security Agency (NSA) could not extract it.
How does spectral – or dual energy – imaging work? Very similar to red and green light used in black-and-white photography. A black-and-white camera provides information on the colours of the photographed objects: an object that is black under red light is actually green.
You’ll find Élie Azoulay everywhere during this year’s International Symposium on Intensive Care and Emergency Medicine (ISICEM).
Since minimally invasive surgery (MIS) entered cardiac surgery in the mid-1990s it became unthinkable not to use this medical specialty. However, MIS procedures do not always result in the best outcome for patients.
Somatom Force – the new computer tomograph (CT) from Siemens – recently had its first public presentation worldwide at the University Medical Centre Mannheim, Germany.
About 500,000 people in France people suffer heart failure (HF). In Europe the figure is six million and the same in the USA.
A new procedure may help people with persistent hypertension. By burning or ablating the nerves in the renal arteries, blood pressure levels can be reduced significantly.
How the different advanced cardio vascular imaging technologies fit together in managing cardiac patients, will be one of the main themes explored at the International Conference on Nuclear Cardiology and Cardiac CT (ICNC 11).
In a Special Focus Session, experts addressed the necessity to perform palliative interventional techniques in cancer treatment and they insisted that interventional radiologists should become more than just technicians.
Procedures, financing and cultural philosophies can shape the difference, Michael Reiter, Mark Nicholls, Eduardo de la Sota, Jane MacDougall report
The use of contrast agents in ultrasound imaging of the gastrointestinal tract is no longer limited to the liver, although the clinical results of hepatic applications continue to be those that are most comprehensively confirmed.
Cardiologists are increasingly concerned about patients with persistent hypertension demanding a new technique, in the absence of clinical proof of its long-term benefit. As more related devices are launched, John Brosky reports on the procedure, drawbacks, and a potential €2 billion market.
Radiation dose reduction in CT angiography can be achieved by reducing the kV settings, reducing the tube voltage, the tube current and by using iterative reconstruction algorithms.
Over 8,000 international clinicians and scientists travelled to Berlin in March to attend the International Liver Congress 2011, hosted by The European Association for the Study of the Liver (EASL), to hear the latest research, perspectives and treatments in hepatology.
Contrast induced nephropathy (CIN) is widely recognised as a potentially serious complication of contrast media use -- a risk that increases with a patient’s age and decreased renal function. Mark Nicholls reports
A multi-centre French study is demonstrating that a four-minute ultrasound scan using a contrast agent can be performed after the first month of treatment and provide quantitative proof of whether a tumour is responding to the therapy.
The 90-minute refresher course ‘Contrast Agent Issues 2010: What the Experts Really Do for Allergies, Contrast-induced Nephropathy, Nephrogenic Systemic Fibrosis, and Extravasation’, to be held during this year’s Radiological Society of North America meeting, will focus on the use of iodinated and gadolinium-based contrast media and the issues, advantages and considerations for patient…
Does diabetes further increase the risk of death in patients diagnosed with cancer? A team at the Johns Hopkins School of Medicine in Baltimore, Maryland, has discovered something very sobering: Cancer patients are 51% to 85% more likely to die after surgical resection if they had pre-existing diabetes.
When in 1992 Dr Luigi Marzio Biasucci, head of the Sub-intensive Care Unit at the Catholic University of the Sacred Heart in Rome, Italy, published with his team the first paper on C-reactive protein (CRP) in unstable angina, few people believed in the diagnostic power of biochemical features to measure the effects or progress of disease, illness, or a condition. Today, biomarker tests are part…
At the end of June a shocking new estimate was released in the UK regarding the number of people unwittingly going about their lives without knowing they are type 2 diabetics – there are just over a million of them. How will the country cope with this discovery and its present diabetic population?
At this year’s ECR, new developments will be outlined during the Contrast agents: Experimental and Clinical session. Mark Nicholls spoke with the session moderator Professor Peter Aspelin, Professor in Diagnostic Radiology at the Karolinska Institute, Stockholm, about their potential.
Patients with chronic heart failure who agree to take part in clinical trials have a better prognosis than those who do not, according to a study reported in the November European Journal of Heart Failure. The finding, say the authors, may even call into question the commonplace ethical requirement of most clinical trials that by choosing not to take part in the study a patient will not be…
Breast-specific gamma imaging (BSGI) is a promising new technology designed to supplement mammography and breast ultrasound examinations when these show suspicious findings. By helping to detect early stage breast cancer it may reduce significantly the number of negative biopsies performed. Dilon Technologies (Newport News, Virginia), pioneer of this technology, received the CE Mark to sell its…
Beckman Coulter, Inc. has expanded its drugs of abuse test menu to include a DRI* Oxycodone Enzyme Immunoassay (OXYX). The assay is for the qualitative and semi-quantitative determination of oxycodone and its metabolite, oxymorphone, in human urine.
Scientists have developed a new test for detecting kidney disease, according to a paper published online in April by Kidney International (www.nature.com/ki/). The technique will allow researchers and clinicians to identify kidney disease or injury within 15 minutes of testing in both rats and humans.
22-26 May Milan, Italy
In a symposium organised by Bayer Schering Pharma at the 2009 European Congress of Radiology (ECR), the audience heard a series of four presentations on the potential advantages of high-signal-intensity contrast agents for MRI, focusing on gadobutrol (Gadovist). During the discussion, several claims made by the speakers were challenged and debated by ECR delegates.
Most professionals will recognise issues that call for consideration in a wider context, a context that does not merely consider strictly professional issues, i.e. issues based upon facts and figures, write Johannes Gossner MD and Joerg Larsen MD FRCR, of the Institute for Roentgendiagnostics, Braunschweig Teaching Hospitals, Germany.
Tumour ablation - and Radiofrequency (RF) ablation in particular - is getting more and more important in oncology. The therapy option offers benefits in terms of costs, ease of set-up and flexibility so that experts see the need to expand the applications of it.
The next flu season will come. To prevent high-risk people from infections, the National Institute for Health and Clinical Excellence (NICE) recently published a final guidance on the use of the drugs oseltamivir, amantadine and zanamivir for the prophylaxis of influenza. "But vaccination is the main way to prevent flu", says Gillian Leng, NICE Deputy Chief Executive.
The BACH (Biomarkers in Acute Congestive Heart Failure) trail, an international, multi-marker study, analysed the diagnostic and prognostic precision of new biomarkers in patients with dyspnea (Shortness of Breath).
London, UK - A Hansen Sensei* robot has been used to perform vascular surgery on a 78-year-old patient for an aneurysm that would have been thought too high-risk for conventional surgery.
Roche reports that, using its NimbleGen CGH arrays, researchers* have identified a recurrent reciprocal genomic rearrangement of chromosomal region 17q12 in foetal samples with congenital anomalies that is also associated with paediatric renal disease and epilepsy.
Stefan G Ruehm, Kambiz Nael, Derek Lohan and Henrik J Michaely* describe impressive images that benefit patient treatment
Scanning the heart's arteries for calcium deposits might be one of the best ways to predict the overall risk of death for adults with cardiac trouble, a new study suggests. This might also help end the controversial discussions about calcium scans.
Developments in MRI over the last few years have revolutionized the diagnosis and therapy of cardiovascular diseases. Contrast-enhanced MR angiography has established itself as a non-invasive, standard procedure for the diagnosis of vascular diseases in the thorax, abdomen and periphery.
Before discussing a possible connection between gadolinium and nephrogenic systemic fibrosis (NSF), Dr Herborn offered a brief background:
Encouraged by the success of the Dual-Source CT system Somatom Definition with two X-ray tubes that simultaneously generate different energies, Siemens Healthcare has already developed six specific dual energy applications. At the ECR 2008, the company presents four new applications that simplify the diagnosis of diseases of the heart, brain, lungs and extremity joints.
Radiological services and equipment are not yet adapted to obese patients. The accuracy of current MRI, CT and Ultrasound is hindered by subcutaneous and intraabdominal fat. These modalities are crucial in diagnosing pathologies associated with obesity, including heart-related disease. Optimising imaging modalities will be a major challenge for radiology.
Since its early beginnings in Europe, during the polio epidemics of the 1950s, intensive care medicine has grown to become a specialty in its own right and the intensive care unit (ICU) occupies an increasingly important position in every hospital. Intensive care doctors are responsible for the management of very sick patients often with multiple and complex disease processes, and ICUs are now…
By A Chkhotua, T Pantsulaia*, N Maglakelidze at the National Centre of Urology, Tbilisi, Georgia
The results of the blood pressure lowering arm of the ADVANCE (Action in Diabetes and Vascular Disease) study, the largest ever trial conducted in people with type 2 diabetes, were recently reported in the Lancet.
Ultrasound examination of the renal tract is one of the primary imaging methods to verify the presence of urinary obstruction, calculi, neoplasms, and other focal findings. This short article summarises important aspects of sonography for some typical renal abnormalities without claiming to be a comprehensive treatment. Since sonography is frequently nonspecific, clinical laboratory findings are…
Already in 1993, the world market for contrast media was thought to be worth $ 3 billion. In 2001, an astonishing 12.2 million contrast medium-supported CT studies were carried out in Europe alone. Currently, the overall sales of contrast media are estimated to rise to $ 915 million in Europe in 2008.
Like any other congress, the 88th German Radiology Congress will present the latest research, workshops and refresher courses.
Osmolality is a simple, rapid and relatively inexpensive procedure that is important in the diagnosis of many physiological conditions, because the measurement of osmolality often provides information that cannot be obtained by any other method.
Nowadays, no radiology conference would be complete without a discussion on turf battles. The rapid development and broad acceptance of cardiac CT has exceeded expectations, and both radiologists and cardiologists are incorporating this technology into their practices. Educational courses on cardiac CT are in high demand and well attended by both radiologists and cardiologists.
A joint project of more than 30 European stroke units just started to examine a potential connection between Fabry disease and stroke in young patients. The results of the worldwide SIFAP (Stroke in Young Fabry Patients) study might give an explanation for some of the 25% of strokes with unknown origin in patients aged 18-55 years.
Less bleeding complications due to safe citrate anticoagulation.
According to leading transplant specialists, within five years almost all renal transplants will be steroid free.
Researchers demonstrated the effectiveness and safety of a new drug for treating bloodstream and heart infections caused by Staphylococcus aureus bacteria.
The fundamental role of inflammation in almost all disease processes has been increasingly recognised over several years.
Article by Stefan G Ruehm MD, Associate Professor of Radiology, Director, Cardiovascular CT, at the David Geffen School of Medicine, UCLA.
Injuries caused by needles and other sharp medical devices - and the related risk of potentially fatal disease transmission - remain a major threat to medical staff.
