Can patients with high anatomic risk but low genomic risk for early-stage ER+/HER2- breast cancer do similarly well without chemotherapy? A new trial aims to evaluate the benefits for this subgroup.
DNA methylation patterns in blood could identify people at high risk of prostate or breast cancer up to eight years before diagnosis, Oxford Population Health researchers report.
A Cambridge study reveals how tumours suppress immune responses – and how blocking this mechanism could make immunotherapies effective in more patients.
The extent of overdiagnosis has been one of the most debated issues in breast cancer screening for decades. Now, a new study suggests that it is less of a problem than previously thought.
AI-enabled spatial analysis can identify patterns in routine pathology slides that may help clinicians identify which patients with pancreatic cancer are at greater risk of recurrence after treatment and surgery, a new study finds.
Monitoring blood test trends alongside unexplained weight loss can provide further clues about a patient’s risk of developing cancer, according to a new study.
A non-invasive urine test detected more than 9 in 10 bladder cancers in a large NHS study – and could reduce urgent cystoscopies significantly.
After treatment for small-cell lung cancer (SCLC), patients often undergo prophylactic radiotherapy to prevent metastases in the brain. Now, a new study shows that MRI surveillance alone is enough, with fewer side-effects.
For many childhood cancers, chemotherapy is the only treatment option. A study explores the trade-off between life-saving treatment at a young age, and delayed side effects unfolding over a lifetime.
Michigan Medicine became the first US healthcare system to launch a DICOM-based digital pathology PACS integrated with its radiology PACS and enterprise imaging network. At SIIM 2026, the annual meeting of the Society for Imaging Informatics in Medicine held in Pittsburgh in June, Mustafa Yousif, MD, and Benjamin Mervak, MD, shared their experience and outlined the key success factors for…
A research team has developed a new class of protein-based MRI contrast agent that detects invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches.
New research offers an explanation for why many men live with prostate cancer for decades while for others it turns lethal: The work identifies which processes cause DNA damage in most of the cancers.
Radiotherapy may be able to do far more than simply destroy tumor cells. A review explores how combining radiotherapy with immunotherapy could improve outcomes for patients with pancreatic cancer.
People with lung cancer are more likely to have microplastics in their lungs and to have larger quantities of microplastics in their lungs, according to new research.
A new study shows how FAPI PET/MRI can help detect the extent of tissue remodeling and fibrosis from endometriosis. This could improve diagnosis of the condition, even in difficult-to-assess areas.
In glioblastoma, the treatment order matters: a new study shows that administering cell immunotherapy before surgery to remove a brain tumour is significantly more effective than the other way around.
Clostridioides difficile does not cause symptoms in infants – but that does not mean the bacteria are harmless: research links colonization to serious long-term consequences for the developing gut.
“Rather than talking about ER-positive or ER-negative breast cancer, we need to view it as a spectrum”: a new classification approach could lead to more personalised treatments.
Exposure of the thymus to radiation during lung cancer treatment is linked to an increased risk of the cancer spreading to other parts of the body and overall worse outcomes, a new study finds.
Surgical treatment of rectal cancer often means complete removal of the rectum. Now, new trial results suggest a different approach that lets patients keep their rectum – along with significant quality-of-life benefits.
This small patch contains tiny microneedles that can gently pass through the outer layer of the skin without drawing blood, to deliver two anti-cancer drugs for localised skin cancer treatment.
Researchers have found an ‘immune organ’ inside the skull, which directs brain defenses. The findings may offer a new way to fight brain cancer and neurodegenerative diseases.
People who take part in screening for colorectal cancer may have as much as 43% lower risk of dying from the disease, according to new estimates from Sweden published in JAMA Network Open.
Cancer metastasis is responsible for at least two-thirds of cancer deaths. Researchers have developed a multi-organ chip that mimics how cancer cells spread to distant organs to gain new insights.
New research has identified a previously unknown mechanism of Kabuki syndrome, a rare genetic disorder. The discovery could open new therapeutic perspectives.
On the way to a patient's “digital twin”: A novel, AI-powered virtual patient simulation system integrating multimodal data is designed to advance personalised cancer treatment.
Digital pathology and spatial omics could enable researchers to see how a tumor's different cell populations function, opening new perspectives for precision cancer therapy.
Invasive fungal infections are notoriously hard to catch early, and even harder to rule out with confidence. At CHU Bordeaux, Dr Frédéric Gabriel has spent years refining how his lab uses β-D-glucan (BDG) testing to sharpen that judgement call – including with the Wako β-glucan test. In this interview, he explains what the guidelines say, what actually happens at the bench, and where he…
As TIL therapy remains difficult to access across Germany and Austria, Sheba offers more than 15 years of experience, in-house cell manufacturing, and one of the world's leading cellular therapy programs for advanced melanoma.
A new study has identified a way to reshape the gut microbiome that can enhance the delivery of certain chemotherapies to tumors, making these nanoparticle-based cancer drugs more effective.
Transgender and gender diverse individuals undergoing gender-affirming mastectomy (‘top surgery’) often lack information on how the procedure will affect breast cancer risk, a new study finds.
As access to TIL therapy remains limited across Europe, Sheba Medical Center combines 15+ years of experience, in-house manufacturing, and pioneering research to advance melanoma and CAR-T therapies.
The members of the American Society for Radiation Oncology (ASTRO) recently elected five new officers to its Board of Directors. Beth Erickson, MD, FASTRO, has been elected President of the medical society.
Results from a recently published clinical trial suggest that combining focused ultrasound with chemotherapy may improve tumor response and survival outcomes in patients with pancreatic cancer.
Using a two-step AI approach, researchers have developed a computationally efficient new method to detect and classify brain tumors from MRI scans more accurately.
Chemotherapy of many childhood cancers leaves specific traces in the DNA, a new study finds. These changes could help clinicians spot treatment resistance earlier, before cancer returns or spreads.
A newly developed AI system analyzes surgeons’ techniques during prostate cancer surgery, helping identify the surgical movements associated with the best patient outcomes.
Low brain metabolism as measured from 18F-FDG PET/CT is associated with higher mortality in patients with advanced non–small cell lung cancer (NSCLC), according to new research.
Tumour-infiltrating lymphocytes are key players in cancer immunotherapy. New research explores the role of location in the tumour microenvironment – knowledge that could help improve treatments.
Photothermal therapy to selectively destroy cancer cells shows promise as a much less invasive treatment option than surgery or radiation. Now, researchers cleared two major hurdles for the method.
A swallowable "nanocage" may offer a new strategy for treating gastric cancer more precisely while reducing damage to healthy tissue, according to findings from a new preclinical study.
A promising predictive model could help women calculate their personal risk for breast cancer, based on non-genetic, genetic and mammographic risk factors, and greatly improve early detection efforts.
A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, new research reveals. The findings could open the door to new ways to prevent cancer metastasis.
Researchers have developed a method to enhance the cellular features in pathology slides based on “structural color” – the same effect that gives peacock feathers their unique sheen.
Ultra-fast delivery, fewer side-effects: Results from the FAST-02 trial show that proton Flash therapy can be safely delivered to cancer patients with metastases in proximity to vital organs.
Detecting genetic mutations associated with lung cancer via laboratory tests can be expensive and time-consuming, and use up valuable tissue from small biopsy samples. A new approach aims to fix this.
A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of prostate cancer patients whose first scan was negative, according to new research.
A multicenter randomized clinical trial shows that real-time AI-assisted colonoscopy significantly improves adenoma detection among individuals at high risk for colorectal cancer.
A blood test for ctDNA may help identify which patients with colorectal cancer that has spread to the liver are most likely to benefit from chemotherapy after surgery, according to new research.
Rare diseases are anything but, with half a million patients in Sweden alone. Still, diagnostic expertise is often limited among healthcare professionals. A new study explores ways to change this.
A new portable ultrasound system could make breast imaging more accessible. The device generates high-res, 3D images of breast tissue, requires no expertise to operate and could be used at home.
Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.
Researchers have developed a new lab model to study BAP1-deficient melanomas, a rare type of melanoma that evade the immune system once they metastasize and are resistant to current immunotherapies.
A pilot study shows that immunotherapy may enable stimulation of egg maturation in women with premature menopause. Three out of ten women gave birth to healthy babies following the treatment.
Tiny algae-based robots guided by magnets could improve bladder cancer treatment by boosting delivery of chemotherapy drugs into tumours, results from a new study suggest.
A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy — a fundamental breakthrough.
AI models can now assess breast cancer risk directly from changes in screening mammograms over time, a new study shows. This opens the door to a new era of dynamic breast cancer risk assessment.
Radiopharmaceutical therapy has already transformed care for neuroendocrine tumors and prostate cancer, but other tumor types still lack targeted treatment options. A new approach could change this.
Measuring radiodensity of visceral fat and muscle from CT scans, researchers have identified a new biomarker that may help determine the prognosis for patients with gastric cancer.
A Taiwanese research team found that BET inhibitors can restore exhausted T cells by reprogramming their metabolism – a potential new strategy for cancer immunotherapy.
AI is transforming the way cancer is diagnosed and treated. Dr Yuri Tolkach shared his group's advances in developing AI-based tools for oncological pathology at the DPAI Europe congress.
A new high-res PET scanner is making its clinical debut at UZ Leuven. The scanner makes it possible to detect earliest signs of brain diseases, years before a patient experiences the first symptoms.
Prof. Johanna Joyce has begun her two-year term as President of the European Association for Cancer Research (EACR), a global community of scientists and clinicians dedicated to advancing the scientific understanding of cancer and its application to improve patient care.
Fragmented care pathways, persistent data gaps and a ‘postcode lottery’ of services continue to undermine the quality of healthcare for women across the United Kingdom. At the HETT25 conference in London, a panel of experts from primary and secondary care, research, femtech and digital health innovation discussed how integrated care models and digital tools can reshape outcomes – and why…
Advanced multiparametric MRI performed before kidney tumor surgery could help identify patients at higher risk for kidney function decline and chronic kidney disease after nephrectomy.
Ultrasound imaging is notoriously difficult to master, as the operator has to mentally arrange a 3D object from 2D images. A new approach using augmented reality (AR) could help speed up the training.
Blood tests show promise for detecting and monitoring cancer. A new method makes it possible to analyse samples containing as little as 5% cancer DNA, compared with the 15–20% required today.
Many people with breast cancer can avoid chemotherapy with a gene test, potentially sparing them side effects without increasing the risk of the cancer returning, a clinical trial has found.
Obesity may change how early-stage breast cancer becomes invasive, according to a new study. The findings could help improve physicians’ ability to predict and treat the disease.
A new AI model enables more efficient analysis of tissue samples taken from colorectal cancer tumours. This can help shorten diagnosis times, reduce costs, and improve diagnostic accuracy.
A simple, affordable urine test could detect early signs of lung cancer months, or even years, before symptoms appear, as well as monitor whether treatment is working and identify potential relapse.
Substantial and sustained weight-loss after bariatric surgery has been linked to a reduced risk of cancer and cancer-related death, mainly in women. Two new studies now provide clues as to why.
Pancreas lesions are of diagnostic concern, as they may evolve into pancreatic cancer – but many never do. New research findings help explain how the transformation into a malignant state works.
Due to advances in radiation therapy, some breast cancer patients may be able to omit surgery following ablative radiation, according to new results of a Phase 2 trial.
A new study shows that diaphragmatic dome height (DDH) - a simple measurement from routine chest X-rays - can help predict survival among patients with lung cancer and breathing disorders.
Once breast cancer begins to metastasise, it generally becomes harder to treat and survival rates are lower. Now, researchers present a new, targeted treatment approach using SBRT radiotherapy.
Researchers have reported results from a first-in-human trial evaluating a novel cell-based platform for localized delivery of interleukin-2 (IL-2) in patients with advanced ovarian cancer.
A new ultrasonic needle for tumour diagnostics could be used to diagnose salivary gland tumours with far greater precision, a new study finds. The device also shows potential for other cancers.
New research reveals that testosterone slows glioblastoma growth—the opposite of the androgen’s effect on tumors outside the brain.
A CRISPR-based tool called Cas12a2 can selectively eliminate cancer and virus-infected cells based on their RNA signature – with high precision and no off-target effects.
Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.
Researchers have used cryo-expansion microscopy to capture cytotoxic T lymphocytes destroying cancer cells in unprecedented 3D detail, opening new paths in immuno-oncology.
Researchers have developed an electrochemical sensor that can detect pancreatic cancer in its early stages. The device offers a simpler, more affordable alternative to conventional tests, which are less accessible.
The incidence of colorectal cancer is rising among younger individuals, sometimes as early as their thirties. The research also shows the challenge of late diagnoses and calls for increased awareness.
A new analytical method could improve how cancer treatments are designed – by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates.
Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.
A new technique to “prime” a patient's immune system before liver transplantation has proven itself in a first-in-human clinical trial to successfully prevent transplant rejection.
Why does the same genetic mutation cause FCDII in some patients but not in others? Researchers developed organoids to model a brain malformation responsible for drug-resistant epilepsy in children.
Researchers have taken an early but promising step toward a cancer therapy that targets and destroys tumor cells with high precision, using a variant of the DNA editing tool CRISPR.
For a young adult, a cancer diagnosis hits different: a more aggressive disease course, greater disruptive potential, longer survivorship. Yet most healthcare institutions seem poorly prepared for this growing patient group. A plenary session at the NCCN 2026 Annual Conference examined a striking shift in modern oncology: the rising incidence of cancer in adolescents and young adults (AYA).
A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.
AI models can generate more complete summaries of complex cancer pathology reports than physicians, according to a new study that tested six models developed by Meta, Google, DeepSeek and Mistral AI.
Researchers have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease.
To improve lung cancer detection, researchers have developed a new AI system that employs a dual approach to analyse CT scans – seeing both detail and context at the same time.
Patient-derived organoids (PDOs), or tumoroids, for pediatric brain cancer show promise in helping researchers find new drugs and better understand the different responses of the tumor.
A new scientific study reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer on a national scale.
As women age, their breast tissue goes through major changes, with the most dramatic changes at menopause, but also during pregnancy and childbirth. A map reveals the impact on breast cancer.
Earlier detection, better outcomes: A new blood test for bowel cancer screening is designed to transform cancer outcomes by moving away from invasive or unpleasant methods.
Medicine has long been regarded as a profession rooted in collaboration. From multidisciplinary teams to shared clinical decision-making, the system depends on cooperation to function effectively. However, behind this collaborative façade exists a parallel competition, one that is rarely discussed openly but widely experienced.
A new review shows that chronic stress may actively drive cancer progression. Therefore, psycho-oncology should be part of standard cancer care, the researchers argue.
The chances of breast cancer recurring remain very low when patients are treated with radiotherapy that is tailored to their individual risk following chemotherapy and surgery, new study results find.
A new X-ray imaging technique could transform how hospitals analyse tissue samples, potentially speeding up diagnoses and improving outcomes for patients, a new study shows.
Fear that their cancer will progress or worsen is one of the most common concerns among people living with this disease. A new tool aims to reliably measure patients’ anxiety about their cancer.
Two new studies explore the role of the thymus – a small organ in the chest, and possibly a missing piece in explaining why people age differently, and why cancer treatments fail in some patients.
At this year’s European Congress of Radiology (ECR) in Vienna, Bayer presented new data on a contrast agent that could transform MRI imaging: gadoquatrane, which requires up to 60% less gadolinium than previous standard macrocyclic preparations whilst maintaining the same diagnostic accuracy. Prof. Hubertus Pietsch, Head of MRI & CT Contrast Agent Research at Bayer and one of the key…
Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.
Women are more likely to survive cancer than men but face a higher risk of serious and adverse side effects from treatment, according to a new international study.
Glioblastoma is notorious for late diagnosis, rapid progression, resistance to treatment and its biological complexity. A new experimental method could help detect this deadly type of brain cancer.
Prostate cancer screening compares favourably to screening for breast cancer in identifying significant cancers, reducing mortality and avoiding unnecessary harms, says new research.
A PSMA PET/CT imaging test could safely halve the number of people who need a biopsy for suspected prostate cancer following inconclusive or reassuring results from an MRI scan, new research finds.
A hidden immune circuit in the uterus revealed: Researchers have discovered a crucial immune switch that sheds light on preeclampsia and early pregnancy failure.
Researchers discovered that pineoblastoma, retinoblastoma and medulloblastoma – severe brain tumours in children that appear to be completely different – actually arise from the same type of cell.
Researchers have discovered a new way to protect the heart during cancer chemotherapy without reducing antitumor efficacy. This could reduce long-term cardiovascular complications for patients.
Breast cancer screening could also be used to screen for cardiovascular disease, new research suggests: The risk of serious or fatal heart disease can be predicted with AI analysis of mammograms.
About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.
The concept of using radiotherapy for osteoarthritis may seem counterintuitive for many clinicians. Yet a well-designed randomised controlled trial presented at the 2025 ASTRO Annual Meeting in San Francisco suggests that low-dose radiotherapy deserves a closer look. The findings add robust evidence to a therapeutic approach that has long been underutilised outside of German-speaking countries.
Artificial intelligence has a critical role to play in supporting clinicians beyond the initial breast cancer diagnosis. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting in Aberdeen, Scotland, Professor Gerald Lip outlined how AI can enhance the performance of modalities such as ultrasound and MRI in supporting clinicians as they plan and deliver treatment for patients.
Functional brain radiosurgery is an application of stereotactic radiosurgery (SRS), representing its newest clinical field. It is a precise, non-invasive medical technique using focused ionising radiation to precisely target specific brain structures to modulate brain function for neurological disorders, psychiatric conditions, or intractable pain. The technology offers “precision without…
Pancreatic cancer remains a diagnostic challenge, due to unspecific early symptoms and lack of effective screening tools. A novel AI metabolomics platform could help overcome these issues.
A small but growing body of evidence suggests that a minimally invasive surgical procedure called lymphovenous anastomosis (LVA) might be an effective treatment for Alzheimer's disease.
Vaccination against human papillomavirus (HPV) reduces the risk of cervical cancer for at least 18 years, according to a new study. There were no signs of waning protection over time.
To better distinguish between healthy and diseased gut microbiomes, scientists have created an index that tracks microbial behavior and signals conditions such as colorectal cancer.
Using machine learning, researchers have trained an electronic nose to detect early signs of ovarian cancer in the blood. The method could eventually be used to find many different cancers.
A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.
Study shows women with stage IV breast cancer detected through screening have a 60% chance of survival ten years after diagnosis – compared to under 20% for those not detected through screening.
New research shows that using ultra-low field (ULF) MRI for breast imaging could offer an alternative to existing breast cancer screening methods and may reduce barriers to screening.
Clues in the CSF: Researchers have developed the first high-precision method that can theoretically diagnose common brain tumors in children and adolescents without surgery.
Radiotherapy is more effective when administered at the right time of day, according to new research. This discovery opens the door to cancer “chronotherapy”, the researchers hope.
Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.
Less cancers missed, fewer complications: Mindfulness enables procedures to be done to a higher standard in awake patients than is currently possible under general anaesthesia or sedation.
Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…
Transgender patients are largely invisible in breast cancer screening statistics – and many never receive an invitation to participate in screening programmes. Guidelines exist, but awareness among referring physicians remains low. Experts say radiology departments are best positioned to lead the change by creating inclusive environments and actively reaching out to this underserved population.…
Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.
Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.
A study of 200 lung cancer patients shows photon-counting CT cuts radiation by 66% and contrast agent by 27% - while delivering sharper images and better tumor detection than conventional CT.
Reseachers show how Candida albicans – a fungus living in our body – can make melanoma more aggressive. The results pave the way for antifungal therapies to complement skin cancer treatments.
MIT researchers have developed a miniaturized ultrasound system that could make it easier for breast ultrasounds to be performed more often, either at home or at a doctor’s office.
Computational pathology is becoming increasingly important in helping deliver precision medicine to a wider range of patients. Experts at the 37th European Congress of Pathology in Vienna discussed how algorithms can optimise laboratory workflows, generate stronger evidence for molecular tumour boards, and enhance clinical trial design.
Beyond "one-size-fits-all": A new strategy that combines two types of PET scans can guide personalized radiotherapy for head and neck cancers, according to new research.
Integrating the patient’s voice: A new study shows access to patient-reported outcome (PRO) data improves the consistency of the evaluation of treatment-related side effects in patients with cancer.
Scientists have shown that a type of laser similar to the one currently used in routine eye surgery could one day help surgeons remove unwanted tissues, such as tumours, with unprecedented accuracy.
Why do some tumours spread while others remain localised? Using colon cancer cells, scientists pinpointed the criteria that influence metastasis risk, and identified a way to assess its probability.
A new type of lab-grown organoid that mimics the behaviour of a human stomach could boost the understanding of rare gastric diseases, researchers say.
Non-specific symptoms such as fatigue, pain or weight loss can be caused by cancer, another serious condition or something completely harmless. A blood test can help provide relevant information.
Chemotherapy does more than kill cancer cells: It reshapes the gut microbiome, making the body less permissive to metastasis. This finding opens new avenues for adjuvant strategies.
A widely used chemotherapy drugs used in cancer treatments can cause heart damage, new research shows. This could be used to adapt treatment regimens - especially in patients with high blood pressure.
Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal cancer, research finds. This leads to better diagnostics and treatment.
Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.
When radiologists at Stockholm's Capio Sankt Görans Hospital began working evenings and weekends to clear mounting backlogs, it became clear that something had to change. The solution? Replacing one of the two radiologists traditionally assigned to read breast cancer screenings with artificial intelligence (AI). The results: fewer false positives, more cancers detected, and radiologists…
A new study shows a significant survival benefit for patients with oropharyngeal cancers treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).
Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.
A novel machine-learning-based solution analyses CT images and helps radiologists detect both malignant and benign lesions in the kidney more quickly and reliably.
A sample of inequality: A new study shows that AI models can infer demographic information from pathology slides, leading to bias in cancer diagnosis among different populations.
Researchers have discovered that low physical activity is associated with a higher risk of lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition.
To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.
Radiotherapy is effective against prostate cancer but can cause side effects. Using AI, scientists found that images originally taken to help position patients could also predict rectal bleeding.
Artificial intelligence is reshaping how clinicians identify women at higher risk of breast cancer – and may soon guide decisions on supplemental screening and treatment. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting in Aberdeen, Scotland, two experts presented their latest findings on AI-driven risk stratification and response prediction.
Breast cancer screening for women under 50 isn't cost-effective – yet 1 in 5 diagnoses occurs in this age group. A new study suggests a personalised approach that could change this equation.
A novel AI-based method can distinguish between progressive brain tumours and radiotherapy-induced necrosis on advanced MRI. This could help clinicians more accurately identify and treat the issues.
Breast imaging for male and transgender patients remains an under-researched field with significant gaps in guidelines and clinical practice. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting, experts presented findings from a pan-European survey on male breast imaging and announced plans for a similar initiative focusing on transgender patients.
After T-cell redirecting therapies, patients are typically hospitalized for several days to watch for side effects. New research shows that these patients can safely be monitored at home.
Two major Dutch hospitals, Catharina Ziekenhuis in Eindhoven and University Medical Center (UMC) Utrecht, are integrating artificial intelligence (AI) from Qure.ai into their chest X-ray workflows.
New immunotherapies are effective against skin cancer, but they can cause serious side effects. New insights suggest that a lower dosage may lead to better outcomes and longer survival.
Many women over 50 schedule mammograms for breast cancer but miss out on CT lung cancer screenings they're also eligible for. Targeted outreach coul help change this, a new study shows.
Should women be told about their high breast density as part of mammography screening? While this may sound like an obvious choice, a new study warns of unintended effects.
IDH mutated gliomas are slow-growing brain tumors with a relatively good prognosis. A new study shows that many patients reveal measurable cognitive impairment in the first year after treatment.
Breast cancer – including aggressive variants – are surprisingly common in younger women, a new study shows. The findings strengthen the case for earlier, risk-tailored screening, the authors say.
While saving lives remains the primary goal, a new study explores how radiation therapy also helps breast cancer survivors return to work. Policymakers should factor this in, the researchers argue.
Researchers developed an X-ray imaging method capable of revealing hidden features in a single shot. This could advance cancer detection, disease monitoring, security screening and material analysis.
A team of researchers comprehensively catalogued a new collection of bacteria-eating viruses called phages. These phages could be used to combat Klebsiella pneumoniae - a serious threat in hospitals.
Delivering a pathology service in resource-constrained locations and developing countries remains a challenge. Cost is a significant barrier, as is the availability of equipment, trained staff and technical and IT support can also hinder a desire from clinicians and pathologists to give their patients a high level of service to help their diagnosis and recovery. The subject was tackled in a…
A major new initiative aims to enable the development of advanced, specific and highly reproducible human in vitro models for greater understanding of disease and the acceleration of new medicines.
Researchers have engineered a novel technique that uses a small balloon to gently widen the airways, and overcome the physical limitations of conventional bronchoscopy to reach deep lung tumors.
New hope for patients with neurological diseases: A combination of focused ultrasound and gene therapy enables targeted, nonsurgical control of seizure-relevant brain regions.
An international research team has discovered a promising new therapeutic approach for aggressive prostate cancer – in the thyroid gland.
Has organ imaging using ultrasound arrived at the same level as cross-sectional imaging? At the annual conference of the German Society for Internal Medicine (DGIM), PD Dr Corinna Trenker presented new technological developments and their diagnostic significance. Despite numerous innovations such as multiparametric protocols and AI support, she made it clear that the human factor remains one of…
Just like the “ABCDE” mnemonic for melanoma awareness, researchers hope their diagnostic tool will transform how doctors approach persistent rashes, reminding them to consider lymphoma sooner.
Using a bioengineered bone marrow model, researchers were able to provide key new information on the efficacy and safety of CAR T-cell therapy for acute myeloid leukaemia (AML), the most common leukaemia in adults.
Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.
Researchers explore how ultrasound waves can be used to activate chemotherapy drugs only in targeted areas, offering a new path toward safer, more effective cancer treatment.
A biosensor that identifies volatile organic compounds (VOCs) in exhaled breath could be used in conjunction with AI to detect various thoracic cancers including lung cancer.
About 60% women in Europe enrolled in a national breast cancer screening programme who have a screening mammogram can feel reasonably confident that radiologists will be able to diagnose early-stage breast cancer. But what about the 30% categorised as having dense breasts, and the 10% who have extremely dense breasts? At the 2025 SBI (Society of Breast Imaging) Breast Imaging Symposium held in…
After a bout of influenza or Covid, the risk of heart attack or stroke may rise dramatically, and chronic infections may increase the long-term risk of serious cardiovascular disease events.
Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…
An international team has developed an AI model that brings together medical imaging data and clinical information to calculate the risk of breast cancer tumour recurrence more accurately.
Many doctors shy away from discussing the aspect of a treatment's sustainability with their patients, expecting a negative reaction. Now, a new study suggests that these fears may be unfounded.
Researchers have discovered a previously unknown mechanism that explains how bacteria within a tumor can drive treatment resistance in patients with oral and colorectal cancer.
Researchers identified a targeted way to protect the brain from harmful side effects of cranial radiation therapy, potentially preserving the quality of life for millions of brain cancer survivors.
A novel imaging solution, called PSMA PET scanning, can more effectively detect the recurrence of prostate cancer compared to standard methods, and is associated with improved survival outcomes.
Rising attendance in mammography screening programmes attest to the fact that women understand the importance of early breast cancer detection. However, the resulting workload increase is a growing challenge for many women’s imaging centres. At the 2025 SBI (Society of Breast Imaging) Symposium, breast imaging specialist Stamatia V. Destounis, MD, discussed her practice’s coping strategies.
Scientists are on the way to finding a vaccine to fight off Helicobacter pylori - a bacterium found in over 60% of people - possibly preventing stomach ulcers and lowering the risk for stomach cancer.
A new type of SPECT imaging provides strong prognostic information to guide prostate cancer treatments according to tumor evolution, significantly impacting patients' overall survival.
Chronic fatigue (ME/CFS) affects millions worldwide, but is poorly understood and has long lacked reliable diagnostic tools. Now, a new blood test claims to diagnose the condition with 96% accuracy.
Breast cancer claims around 670.000 lives each year. Now, researchers propose that whole genome sequencing (WGS) could help many patients find better treatments or match them with clinical trials.
Precision Oncology Ireland (POI), a €28M cancer research programme uniting universities, charities and industry to develop tailored diagnostic and therapeutic solutions, has now entered phase 2.
GLP-1 receptor agonists are widely prescribed for individuals with diabetes and weight loss. However, these medications may adversely affect the interpretation of cancer imaging, new research finds.
Stroke patients in four NHS hospitals are now receiving genetic tests that determine whether a commonly prescribed drug will work for them – a breakthrough that could transform treatment for millions. Digital approaches are spearheading a drive to help make genomic medicine part of everyday care. The role of digital tools was a central theme at the HETT (Healthcare Excellence Through…
Researchers have developed a tool to quickly quantify changes in the branches of mouse mammary glands. This could one day be used to detect early warning signs of breast cancer.
The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.
Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.
Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.
Scientists have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body’s immune response.
Breast cancer survivors are often discouraged from undergoing hormone replacement therapy (HRT) to alleviate menopause symptoms. Now, new research paints a more differentiated picture.
This year, the Journées Francophones de Radiologie (JFR) will carry a clinical ambition as simple as it is essential: to shine a spotlight on those who are often overlooked. Under the presidency of Professor Mathieu Lederlin, thoracic radiologist at Rennes University Hospital, vulnerable patients will be at the heart of the annual meeting of the French Society of Radiology that will unfold…
Researchers from the University of Birmingham’s Bladder Cancer Research Centre have found a new way of detecting tumour DNA in urine to identify bladder cancer.
TU München researchers discover how chronic cellular stress changes gut microbiome composition, promoting cancer development through altered lipid metabolism.
Study of 3.7 million children reveals small but significant increased risk of blood cancers from medical imaging radiation, with CT scans posing highest risk
University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.
Using AI to help detect one of the leading killers of women worldwide: A new machine learning model can successfully predict heart disease risk in women by analysing mammograms.
Misinterpreting the malignancy risk of lung nodules often results in high false-positive rates, unnecessary follow-ups, increased patient anxiety and healthcare costs. A new study suggests that AI can fix this.
Digital transformation, including AI, is key to improving healthcare services - but this may be easier said than done: A new UK study identifies hurdles for AI implementation in NHS hospitals.
A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumours in some cancers.
A squishy new ‘artificial cartilage’ material could improve arthritis treatments by releasing anti-inflammatory drugs in response to a flare-up.
In metastatic EGFR-mutated non-small cell lung cancer (NSCLC), targeting residual disease through surgery can extend the benefits of EGFR TKI therapy beyond standard monotherapy, a new study finds.
Researchers explored two promising new biomarkers as potential radiotheranostic targets for endometrial cancer. This could help identify patients who are likely to respond to targeted therapeutics.
Currently, cancer treatment evaluation focuses heavily on survival outcomes, but doesn't adequately consider how treatments affect quality of life. A new policy review aims to change this.
AI may be effective at detecting advanced breast cancer in mammograms, but current models still lack reliability. New research from Korea suggests that up to 14% of invasive cases are missed.
Researchers have developed a machine learning algorithm that uses cardiac MRI images to help identify breast cancer patients who may be at risk of cardiotoxicity during cancer treatment. The research, led by cardiologist Dr Paaladinesh Thavendiranathan, was presented at the European Society of Cardiology's Cardio-Oncology Conference in Florence in June.
A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.
An advanced imaging method that uses the natural glow of tissues could help detect subtle differences in the tissue’s biochemistry, offering a way to earlier detect colorectal cancer via endoscopy.
One in three people do not want to know about serious illnesses—even if they might be affected themselves. A new review study explores the reasons for this deliberate ignorance.
Self-learning artificial intelligence approaches are offering a number of advantages for digital pathology when compared to established AI options. The benefits, which range from greater speed and capacitive flexibility to ‘wholly interpretable’ analyses, were outlined at the Digital Pathology and AI Congress in London.
A newly developed method to accurately quantify how much radiation is absorbed by the blood during cancer treatment could lead to more personalised, preventive, and safer radiotherapy.
Scientists developed an AI-based approach to diagnose colorectal cancer from different microbial subgroups in the gut microbiota – a non-invasive and low-cost alternative to colonoscopy screening.
Patient communication facilitated by chatbots, image quality optimized by machine learning: Artificial intelligence (AI) is entering radiology at breakneck speed, transforming the specialty almost beyond recognition. So, how will the future of diagnostic imaging under AI look like, and which role will humans still play in it? At the ECR congress in Vienna, experts explored the societal and…
Men assessed as healthy may still have an early form of prostate cancer. Using AI, researchers found signs that were missed in more than 80% of samples of men who later developed cancer.
Studies have found that natural polysaccharides from a medical fungus endemic to Taiwan can not only effectively inhibit inflammation, but also fight the proliferation of lung cancer cells.
Tracer molecules serve to provide visual guidance in nuclear medicine, but a new molecule could give surgeons additional audio cues to help them locate prostate cancer tumors and metastases.
An artificial heart valve made from SEBS, a new type of highly durable and biocompatible plastic, could be a step closer to use in humans, following a successful long-term safety test in animals.
Researchers report they have built a new non-toxic and non-radioactive handheld device that uses the unique properties of diamonds to diagnose metastasized breast cancer.
Mammography image interpretation AI models are unreliable – but so are human readers. A new hybrid strategy could reduce radiologist workload by 38% without compromising diagnostic efficacy.
The mere fact of being exposed to a sick avatar in a virtual reality environment triggers a measurable immune response in humans, a multidisciplinary research team discovered.
Gadolinium-based contrast agents enhance visibility but also pose a significant health risk. A new AI-powered virtual MRI imaging technique is designed to offer a safer diagnostic approach.
More clinically relevant tumors detected at an earlier stage and at lower costs: New research finds that AI can replace the second radiologist in the Dutch breast cancer screening program.
AI tools for adenoma polyp detection are designed to help increase the accuracy of colonoscopies. However, a new study finds that using AI may lead to loss of detection skills in health professionals.
New research suggests that KFRE, a common prognostic tool to predict kidney failure, could underestimate the risk for individuals with chronic kidney disease (CKD) who also have frailty.
The vaginal microbiome is a largely overlooked area of medicine that could dramatically improve outcomes for common infections, infertility and even cancer for millions of women, a new review finds.
A multicenter study involving leading hospitals across Spain, has confirmed that people with COPD show altered levels of specific metabolites in their blood.
Microsatellite instability-high (MSI-H) tumors are associated with better clinical outcomes. A novel AI model for accurate MSI prediction could help battle gastric and colorectal cancers.
Some medications can only be taken as an injection, which is often painful, unpleasant and inconvenient for patients. A new transport system could make it possible to swap these injections for pills.
Do laboratory tests using blood-based biomarkers (BBB) represent the next type of universally recommended screening tests for Alzheimer's disease (AD)? Experts curb the high expectations for this type of diagnostic tool.
Tumor vesicles may serve as early indicators of cancer and help monitor the effectiveness of treatments. Now, researchers discovered a new way to detect these vesicles.
Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.
Classifying prostate cancer as “low-grade” could create a false sense of security and delay definitive treatments. A new study shows that the biopsy grade alone can paint an incomplete picture.
Common respiratory infections such as influenza and Covid-19 can awaken dormant breast cancer cells that have spread to the lungs, setting the stage for new metastatic tumors, new research finds.
How cancer cells survive the journey through the body to form metastases is still poorly understood. New insights into how cells survive intense physical stress could pave the way for new treatments.
Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.
By analyzing CT images with 3D software, researchers demonstrated that small liver tumors can be successfully treated using ablation. This could enable more confident use of ablation treatments.
