News • Urologie
Urine test detects 9 in 10 bladder cancers in NHS study
A non-invasive urine test detected more than 9 in 10 bladder cancers in a large NHS study – and could reduce urgent cystoscopies significantly.
Search for: "cancer research" - 250 articles found
News • Prophylactic post-treatment
MRI surveillance after SCLC helps patients avoid brain irradiation
After treatment for small-cell lung cancer (SCLC), patients often undergo prophylactic radiotherapy to prevent metastases in the brain. Now, a new study shows that MRI surveillance alone is enough, with fewer side-effects.
News • Impact on healthy tissues uncovered
Study explores cost of childhood chemotherapy
For many childhood cancers, chemotherapy is the only treatment option. A study explores the trade-off between life-saving treatment at a young age, and delayed side effects unfolding over a lifetime.
Article • Enterprise imaging
From slides to PACS: A blueprint for digital pathology integration
Michigan Medicine became the first US healthcare system to launch a DICOM-based digital pathology PACS integrated with its radiology PACS and enterprise imaging network. At SIIM 2026, the annual meeting of the Society for Imaging Informatics in Medicine held in Pittsburgh in June, Mustafa Yousif, MD, and Benjamin Mervak, MD, shared their experience and outlined the key success factors for…
News • Collagen-targeted protein CA
New MRI agent to earlier detect lung cancer, hidden metastases
A research team has developed a new class of protein-based MRI contrast agent that detects invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches.
News • Mutational process analysis
Scientists explore DNA damage in prostate cancer for better predictions
New research offers an explanation for why many men live with prostate cancer for decades while for others it turns lethal: The work identifies which processes cause DNA damage in most of the cancers.
News • Promising treatment synergies
Pancreatic cancer radiotherapy could also boost immunotherapy
Radiotherapy may be able to do far more than simply destroy tumor cells. A review explores how combining radiotherapy with immunotherapy could improve outcomes for patients with pancreatic cancer.
News • Environmental exposure
Researchers explore link between microplastics and lung cancer
People with lung cancer are more likely to have microplastics in their lungs and to have larger quantities of microplastics in their lungs, according to new research.
News • FAP-targeted imaging
PET/MRI shows promise in endometriosis detection
A new study shows how FAPI PET/MRI can help detect the extent of tissue remodeling and fibrosis from endometriosis. This could improve diagnosis of the condition, even in difficult-to-assess areas.
News • Immunotherapy first, surgery afterwards
Glioblastoma: treatment sequence matters
In glioblastoma, the treatment order matters: a new study shows that administering cell immunotherapy before surgery to remove a brain tumour is significantly more effective than the other way around.
News • Study challenges long-held assumptions
C. diff: not so harmless for the infant gut
Clostridioides difficile does not cause symptoms in infants – but that does not mean the bacteria are harmless: research links colonization to serious long-term consequences for the developing gut.
News • Alternate to standard classification
Breast cancer should be viewed as a spectrum, new study suggests
“Rather than talking about ER-positive or ER-negative breast cancer, we need to view it as a spectrum”: a new classification approach could lead to more personalised treatments.
News • Adverse effects of lung cancer treatment
Collateral damage: the thymus in NSCLC radiotherapy
Exposure of the thymus to radiation during lung cancer treatment is linked to an increased risk of the cancer spreading to other parts of the body and overall worse outcomes, a new study finds.
News • Promising trial results
Rectal cancer treatment spares surgery for most patients
Surgical treatment of rectal cancer often means complete removal of the rectum. Now, new trial results suggest a different approach that lets patients keep their rectum – along with significant quality-of-life benefits.
News • Biphasic drug delivery system
3D-printed microneedle patch could improve skin cancer treatment
This small patch contains tiny microneedles that can gently pass through the outer layer of the skin without drawing blood, to deliver two anti-cancer drugs for localised skin cancer treatment.
News • Researchers explore role of lymphoid structures
‘Immune organ’ inside skull could help fight brain cancer
Researchers have found an ‘immune organ’ inside the skull, which directs brain defenses. The findings may offer a new way to fight brain cancer and neurodegenerative diseases.
News • Reduction of mortality
New study shows effectiveness of bowel cancer screening
People who take part in screening for colorectal cancer may have as much as 43% lower risk of dying from the disease, according to new estimates from Sweden published in JAMA Network Open.
News • Tissue model mimics colonization
'Metastasis-on-a-chip' to advance understanding of cancer spread
Cancer metastasis is responsible for at least two-thirds of cancer deaths. Researchers have developed a multi-organ chip that mimics how cancer cells spread to distant organs to gain new insights.
News • Research explores key role of chromatin
Kabuki syndrome: new insights offer hope for therapies
New research has identified a previously unknown mechanism of Kabuki syndrome, a rare genetic disorder. The discovery could open new therapeutic perspectives.
News • NSCLC immunotherapy response prediction
AI-powered “virtual patient” to advance personalised cancer treatment
On the way to a patient's “digital twin”: A novel, AI-powered virtual patient simulation system integrating multimodal data is designed to advance personalised cancer treatment.
News • Deep visual multi-omics profiling
Digital pathology AI to break down tumor cell populations
Digital pathology and spatial omics could enable researchers to see how a tumor's different cell populations function, opening new perspectives for precision cancer therapy.
Sponsored • Produced in partnership with FUJIFILM Wako
Putting β-glucan testing into everyday practice for fungal infections
Invasive fungal infections are notoriously hard to catch early, and even harder to rule out with confidence. At CHU Bordeaux, Dr Frédéric Gabriel has spent years refining how his lab uses β-D-glucan (BDG) testing to sharpen that judgement call – including with the Wako β-glucan test. In this interview, he explains what the guidelines say, what actually happens at the bench, and where he…
Sponsored • TIL Therapy for Advanced Melanoma
Why Germans & Austrians Choose Sheba for TIL Therapy & Melanoma Care
As TIL therapy remains difficult to access across Germany and Austria, Sheba offers more than 15 years of experience, in-house cell manufacturing, and one of the world's leading cellular therapy programs for advanced melanoma.
News • Nanomedicine
Reshaping the gut microbiome to boost chemotherapy
A new study has identified a way to reshape the gut microbiome that can enhance the delivery of certain chemotherapies to tumors, making these nanoparticle-based cancer drugs more effective.
News • Research identifies information barriers
‘Top surgery’ and breast cancer risk: Towards informed decision-making
Transgender and gender diverse individuals undergoing gender-affirming mastectomy (‘top surgery’) often lack information on how the procedure will affect breast cancer risk, a new study finds.
Sponsored • Tumor-infiltrating lymphocyte therapy
Sheba Is Giving Europeans Greater Access to TIL Therapy for Metastatic Melanoma
As access to TIL therapy remains limited across Europe, Sheba Medical Center combines 15+ years of experience, in-house manufacturing, and pioneering research to advance melanoma and CAR-T therapies.
Dr. Beth Erickson
Showing patients and the medical community what radiation therapy can achieve
The members of the American Society for Radiation Oncology (ASTRO) recently elected five new officers to its Board of Directors. Beth Erickson, MD, FASTRO, has been elected President of the medical society.
News • Improved tumor response and survival outcomes
Focused ultrasound may enhance chemotherapy for pancreatic cancer
Results from a recently published clinical trial suggest that combining focused ultrasound with chemotherapy may improve tumor response and survival outcomes in patients with pancreatic cancer.
News • Advanced deep learning approach
Two-step AI system detects brain tumors from MRI
Using a two-step AI approach, researchers have developed a computationally efficient new method to detect and classify brain tumors from MRI scans more accurately.
News • Pediatric oncology
"Genomic fingerprints" left by chemotherapy could point to more precise cancer treatments
Chemotherapy of many childhood cancers leaves specific traces in the DNA, a new study finds. These changes could help clinicians spot treatment resistance earlier, before cancer returns or spreads.
News • Gesture sequence recognition and clinical outcome prediction
Prostate cancer: AI analyzes surgical technique to improve care
A newly developed AI system analyzes surgeons’ techniques during prostate cancer surgery, helping identify the surgical movements associated with the best patient outcomes.
News • Lung cancer insights
Brain metabolism predicts survival in advanced NSCLC patients
Low brain metabolism as measured from 18F-FDG PET/CT is associated with higher mortality in patients with advanced non–small cell lung cancer (NSCLC), according to new research.
News • New insights on TILs
Immune cells in the tumour microenvironment: Better near than far away?
Tumour-infiltrating lymphocytes are key players in cancer immunotherapy. New research explores the role of location in the tumour microenvironment – knowledge that could help improve treatments.
News • Promising method
Photothermal therapy: Towards minimally invasive cancer treatment
Photothermal therapy to selectively destroy cancer cells shows promise as a much less invasive treatment option than surgery or radiation. Now, researchers cleared two major hurdles for the method.
News • Swallowable nanoscale delivery platform
Gastric cancer: nanocages could bring targeted treatment in a pill
A swallowable "nanocage" may offer a new strategy for treating gastric cancer more precisely while reducing damage to healthy tissue, according to findings from a new preclinical study.
News • Prediction model
Building a “calculator” for breast cancer risk
A promising predictive model could help women calculate their personal risk for breast cancer, based on non-genetic, genetic and mammographic risk factors, and greatly improve early detection efforts.
News • Commensal dysbiosis
Study links bile acid buildup to breast cancer metastasis
A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, new research reveals. The findings could open the door to new ways to prevent cancer metastasis.
News • Stain-Free Histology
Nanophotonic slides add color to tissue samples
Researchers have developed a method to enhance the cellular features in pathology slides based on “structural color” – the same effect that gives peacock feathers their unique sheen.
News • Fast, ultra-high dose treatment
Proton Flash radiotherapy effective for thoracic bone metastases
Ultra-fast delivery, fewer side-effects: Results from the FAST-02 trial show that proton Flash therapy can be safely delivered to cancer patients with metastases in proximity to vital organs.
News • Fluorescence lifetime imaging microscopy
New technique could aid targeted lung cancer treatment
Detecting genetic mutations associated with lung cancer via laboratory tests can be expensive and time-consuming, and use up valuable tissue from small biopsy samples. A new approach aims to fix this.
News • After an initial negative scan
Treatment change for prostate cancer: study reveals benefit of second PSMA PET
A second prostate-specific membrane antigen (PSMA) PET scan changed treatment plans for nearly half of prostate cancer patients whose first scan was negative, according to new research.
News • "Second pair of eyes" for endoscopists
Colorectal cancer: AI-assisted colonoscopy improves adenoma detection
A multicenter randomized clinical trial shows that real-time AI-assisted colonoscopy significantly improves adenoma detection among individuals at high risk for colorectal cancer.
News • Circulating tumor DNA status
Colorectal cancer: blood test shows who benefits from chemotherapy after surgery
A blood test for ctDNA may help identify which patients with colorectal cancer that has spread to the liver are most likely to benefit from chemotherapy after surgery, according to new research.
News • National quality registry
Building infrastructure for better rare disease care
Rare diseases are anything but, with half a million patients in Sweden alone. Still, diagnostic expertise is often limited among healthcare professionals. A new study explores ways to change this.
News • Operator-independent breast cancer screening
Portable ultrasound system takes the hard part out of breast imaging
A new portable ultrasound system could make breast imaging more accessible. The device generates high-res, 3D images of breast tissue, requires no expertise to operate and could be used at home.
News • Exploring the landscape of tumour methylation
Parsing the pathology of prostate cancer
Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.
News • CRISPR-Cas9-based approach
New laboratory tool to find better treatments for resistant melanomas
Researchers have developed a new lab model to study BAP1-deficient melanomas, a rare type of melanoma that evade the immune system once they metastasize and are resistant to current immunotherapies.
News • Premature ovarian insufficiency
Immunotherapy may temporarily restore fertility in premature menopause patients
A pilot study shows that immunotherapy may enable stimulation of egg maturation in women with premature menopause. Three out of ten women gave birth to healthy babies following the treatment.
News • Magnet-controlled chemotherapy delivery
Treating bladder cancer with algae-based robots
Tiny algae-based robots guided by magnets could improve bladder cancer treatment by boosting delivery of chemotherapy drugs into tumours, results from a new study suggest.
News • Treatment-resistant tumours
Researchers tear off "invisibility cloak" of colon cancer
A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy — a fundamental breakthrough.
News • Longitudinal AI analysis
Deep learning predicts breast cancer risk from changes in mammograms
AI models can now assess breast cancer risk directly from changes in screening mammograms over time, a new study shows. This opens the door to a new era of dynamic breast cancer risk assessment.
News • Focus on FAP
New radiopharmaceutical therapy shows broad effectiveness across multiple cancers
Radiopharmaceutical therapy has already transformed care for neuroendocrine tumors and prostate cancer, but other tumor types still lack targeted treatment options. A new approach could change this.
News • Body composition radiodensity
New CT-based marker to refine gastric cancer prognosis
Measuring radiodensity of visceral fat and muscle from CT scans, researchers have identified a new biomarker that may help determine the prognosis for patients with gastric cancer.
News • Reviving exhausted immune cells
A new way to boost cancer immunotherapy
A Taiwanese research team found that BET inhibitors can restore exhausted T cells by reprogramming their metabolism – a potential new strategy for cancer immunotherapy.
Article • Digital pathology
From single-tumour to pan-cancer AI diagnostics
AI is transforming the way cancer is diagnosed and treated. Dr Yuri Tolkach shared his group's advances in developing AI-based tools for oncological pathology at the DPAI Europe congress.
News • Neurology
New high resolution PET scanner reveals early signs of brain diseases
A new high-res PET scanner is making its clinical debut at UZ Leuven. The scanner makes it possible to detect earliest signs of brain diseases, years before a patient experiences the first symptoms.
Prof. Johanna Joyce
Advancing cancer research across Europe and beyond
Prof. Johanna Joyce has begun her two-year term as President of the European Association for Cancer Research (EACR), a global community of scientists and clinicians dedicated to advancing the scientific understanding of cancer and its application to improve patient care.
Article • Experts call for joined-up NHS services
Reshaping women’s healthcare – from postcode lottery to personalised pathways
Fragmented care pathways, persistent data gaps and a ‘postcode lottery’ of services continue to undermine the quality of healthcare for women across the United Kingdom. At the HETT25 conference in London, a panel of experts from primary and secondary care, research, femtech and digital health innovation discussed how integrated care models and digital tools can reshape outcomes – and why…
News • Renal function deterioration
MRI could predict kidney disease before it develops, study suggests
Advanced multiparametric MRI performed before kidney tumor surgery could help identify patients at higher risk for kidney function decline and chronic kidney disease after nephrectomy.
Video • 3D augmented-reality imaging
AR could help users wrap their head around medical ultrasound
Ultrasound imaging is notoriously difficult to master, as the operator has to mentally arrange a 3D object from 2D images. A new approach using augmented reality (AR) could help speed up the training.
News • BayesCNA
New blood analysis method to improve cancer care
Blood tests show promise for detecting and monitoring cancer. A new method makes it possible to analyse samples containing as little as 5% cancer DNA, compared with the 15–20% required today.
News • OPTIMA trial results
Gene test could safely spare breast cancer patients of chemotherapy
Many people with breast cancer can avoid chemotherapy with a gene test, potentially sparing them side effects without increasing the risk of the cancer returning, a clinical trial has found.
News • Metabolic health
Obesity helps breast cancer become invasive
Obesity may change how early-stage breast cancer becomes invasive, according to a new study. The findings could help improve physicians’ ability to predict and treat the disease.
News • dMMR prediction
AI helps analyse colorectal cancer samples
A new AI model enables more efficient analysis of tissue samples taken from colorectal cancer tumours. This can help shorten diagnosis times, reduce costs, and improve diagnostic accuracy.
News • Focus on cellular senescence
Urine test could help detect lung cancer years before symptoms occur
A simple, affordable urine test could detect early signs of lung cancer months, or even years, before symptoms appear, as well as monitor whether treatment is working and identify potential relapse.
News • Sex-specific effects of bariatric surgery
Why weight-loss surgery lowers cancer risk in women
Substantial and sustained weight-loss after bariatric surgery has been linked to a reduced risk of cancer and cancer-related death, mainly in women. Two new studies now provide clues as to why.
News • Asynchronous evolution
How early pancreas lesions become cancerous
Pancreas lesions are of diagnostic concern, as they may evolve into pancreatic cancer – but many never do. New research findings help explain how the transformation into a malignant state works.
News • Promising results for low-risk women
Radiotherapy advances may let breast cancer patients skip surgery
Due to advances in radiation therapy, some breast cancer patients may be able to omit surgery following ablative radiation, according to new results of a Phase 2 trial.
News • Diaphragmatic dome height
Simple X-ray measure linked to survival in lung cancer surgery patients
A new study shows that diaphragmatic dome height (DDH) - a simple measurement from routine chest X-rays - can help predict survival among patients with lung cancer and breathing disorders.
News • SBRT for longer control
Targeted radiotherapy shows promise against metastatic breast cancer
Once breast cancer begins to metastasise, it generally becomes harder to treat and survival rates are lower. Now, researchers present a new, targeted treatment approach using SBRT radiotherapy.
News • Targeted immunotherapy
Implantable cytokine factories to help treat ovarian cancer
Researchers have reported results from a first-in-human trial evaluating a novel cell-based platform for localized delivery of interleukin-2 (IL-2) in patients with advanced ovarian cancer.
News • Larger sample yield
Ultrasonic needle could reshape cancer diagnostics
A new ultrasonic needle for tumour diagnostics could be used to diagnose salivary gland tumours with far greater precision, a new study finds. The device also shows potential for other cancers.
News • Importance of tumor location
Testosterone slows glioblastoma growth in men
New research reveals that testosterone slows glioblastoma growth—the opposite of the androgen’s effect on tumors outside the brain.
News • Research
CRISPR tool targets cancer and virus-infected cells precisely
A CRISPR-based tool called Cas12a2 can selectively eliminate cancer and virus-infected cells based on their RNA signature – with high precision and no off-target effects.
News • Oncology
Nanozymes take on brain tumours from the inside
Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.
News • Immuno-Oncology
Killer cells caught in the act: a 3D view of T lymphocytes
Researchers have used cryo-expansion microscopy to capture cytotoxic T lymphocytes destroying cancer cells in unprecedented 3D detail, opening new paths in immuno-oncology.
News • Alternative to conventional tests
Affordable biosensor to early detect pancreatic cancer
Researchers have developed an electrochemical sensor that can detect pancreatic cancer in its early stages. The device offers a simpler, more affordable alternative to conventional tests, which are less accessible.
News • Swiss national study reveals
Colorectal cancer on the rise among people under 50
The incidence of colorectal cancer is rising among younger individuals, sometimes as early as their thirties. The research also shows the challenge of late diagnoses and calls for increased awareness.
News • Targeted analysis
New technique maps cancer drug uptake inside living cells
A new analytical method could improve how cancer treatments are designed – by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates.
News • Mammary tumorigenesis
New marker identifies which breast lesions will progress to cancer
Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.
News • Transplant organ acceptance
“Immune priming” prevents donor liver rejection
A new technique to “prime” a patient's immune system before liver transplantation has proven itself in a first-in-human clinical trial to successfully prevent transplant rejection.
News • Focal cortical dysplasia
Lab-grown mini-brains shed light on childhood epilepsy
Why does the same genetic mutation cause FCDII in some patients but not in others? Researchers developed organoids to model a brain malformation responsible for drug-resistant epilepsy in children.
News • Methylation-sensitive editing by Cas9
Targeting tumour DNA with CRISPR variant
Researchers have taken an early but promising step toward a cancer therapy that targets and destroys tumor cells with high precision, using a variant of the DNA editing tool CRISPR.
Article • Experts explore often-overlooked patient group in oncology
A rising tide: cancer in young adults
For a young adult, a cancer diagnosis hits different: a more aggressive disease course, greater disruptive potential, longer survivorship. Yet most healthcare institutions seem poorly prepared for this growing patient group. A plenary session at the NCCN 2026 Annual Conference examined a striking shift in modern oncology: the rising incidence of cancer in adolescents and young adults (AYA).
News • Prediction of treatment response
Colon and rectal cancer: new biomarker shows which patients benefit from immunotherapy
A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.
News • Open-source AI models put to the test
LLMs outperform doctors at summarizing complex cancer pathology reports
AI models can generate more complete summaries of complex cancer pathology reports than physicians, according to a new study that tested six models developed by Meta, Google, DeepSeek and Mistral AI.
News • Genetic CAD risk scores
Researchers link diabetes subgroups to coronary heart disease risk
Researchers have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease.
News • Hybrid deep learning approach
"Double vision" AI system to detect lung cancer from CT scans
To improve lung cancer detection, researchers have developed a new AI system that employs a dual approach to analyse CT scans – seeing both detail and context at the same time.
News • Ependymoma and medulloblastoma tumoroids
New organoids offer deeper insights into pediatric brain cancer
Patient-derived organoids (PDOs), or tumoroids, for pediatric brain cancer show promise in helping researchers find new drugs and better understand the different responses of the tumor.
News • Environmental medicine
New study links pesticide exposure to cancer risk
A new scientific study reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer on a national scale.
News • Single-cell spatial atlas
Breast cancer: map explores role of aging tissue
As women age, their breast tissue goes through major changes, with the most dramatic changes at menopause, but also during pregnancy and childbirth. A map reveals the impact on breast cancer.
News • Inflammatory marker detection
New blood test targets rising bowel cancer rates
Earlier detection, better outcomes: A new blood test for bowel cancer screening is designed to transform cancer outcomes by moving away from invasive or unpleasant methods.
Article • Exploring unspoken systems
The hidden culture of competition in medicine: A system-level challenge
Medicine has long been regarded as a profession rooted in collaboration. From multidisciplinary teams to shared clinical decision-making, the system depends on cooperation to function effectively. However, behind this collaborative façade exists a parallel competition, one that is rarely discussed openly but widely experienced.
News • Review on treatment outcomes
Exploring the impact of chronic stress on cancer
A new review shows that chronic stress may actively drive cancer progression. Therefore, psycho-oncology should be part of standard cancer care, the researchers argue.
News • Treatment de-escalation
Patient-tailored radiotherapy effectively prevents breast cancer recurrence
The chances of breast cancer recurring remain very low when patients are treated with radiotherapy that is tailored to their individual risk following chemotherapy and surgery, new study results find.
News • Histopathology tool
New X-ray technique could transform tissue diagnosis
A new X-ray imaging technique could transform how hospitals analyse tissue samples, potentially speeding up diagnoses and improving outcomes for patients, a new study shows.
News • Disease-related distress
Cancer-related anxiety: tool reveals emotional impact
Fear that their cancer will progress or worsen is one of the most common concerns among people living with this disease. A new tool aims to reliably measure patients’ anxiety about their cancer.
News • Impact on longevity and cancer
“The thymus has been overlooked for decades”
Two new studies explore the role of the thymus – a small organ in the chest, and possibly a missing piece in explaining why people age differently, and why cancer treatments fail in some patients.
Sponsored • New study data presented at ECR 2026
Redrawing contrast dose limits in MRI
At this year’s European Congress of Radiology (ECR) in Vienna, Bayer presented new data on a contrast agent that could transform MRI imaging: gadoquatrane, which requires up to 60% less gadolinium than previous standard macrocyclic preparations whilst maintaining the same diagnostic accuracy. Prof. Hubertus Pietsch, Head of MRI & CT Contrast Agent Research at Bayer and one of the key…
News • PARP inhibitors distribution
“Hidden drug storehouses” could explain treatment resistance in cancer
Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.
News • Study explores cost of survival
Women more likely to survive cancer but suffer more severe side effects
Women are more likely to survive cancer than men but face a higher risk of serious and adverse side effects from treatment, according to a new international study.
News • Neuro-oncology
Simple blood test could detect glioblastoma in the future
Glioblastoma is notorious for late diagnosis, rapid progression, resistance to treatment and its biological complexity. A new experimental method could help detect this deadly type of brain cancer.
News • Comparison study
Prostate cancer screening on par with breast cancer screening
Prostate cancer screening compares favourably to screening for breast cancer in identifying significant cancers, reducing mortality and avoiding unnecessary harms, says new research.
News • Nuclear imaging in urology
Prostate cancer: PSMA PET/CT could cut need for biopsies
A PSMA PET/CT imaging test could safely halve the number of people who need a biopsy for suspected prostate cancer following inconclusive or reassuring results from an MRI scan, new research finds.
News • Critical role of NFAT
Preventing pregnancy complications with new immune insights
A hidden immune circuit in the uterus revealed: Researchers have discovered a crucial immune switch that sheds light on preeclampsia and early pregnancy failure.
News • Unexpected similarities
Different tumours, same origin: Surprising discovery in paediatric brain cancers
Researchers discovered that pineoblastoma, retinoblastoma and medulloblastoma – severe brain tumours in children that appear to be completely different – actually arise from the same type of cell.
News • Conditioning against cardiotoxicity
Chemotherapy: protecting the heart without compromising anticancer efficacy
Researchers have discovered a new way to protect the heart during cancer chemotherapy without reducing antitumor efficacy. This could reduce long-term cardiovascular complications for patients.
News • Quantification of arterial calcifications
AI predicts heart disease risk from mammograms
Breast cancer screening could also be used to screen for cardiovascular disease, new research suggests: The risk of serious or fatal heart disease can be predicted with AI analysis of mammograms.
News • Triple-negative breast cancer
TNBC can become treatment-resistant in more ways than one
About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.
Article • Beyond drugs and surgery
Radiation for joint pain? Study validates low-dose approach for knee osteoarthritis
The concept of using radiotherapy for osteoarthritis may seem counterintuitive for many clinicians. Yet a well-designed randomised controlled trial presented at the 2025 ASTRO Annual Meeting in San Francisco suggests that low-dose radiotherapy deserves a closer look. The findings add robust evidence to a therapeutic approach that has long been underutilised outside of German-speaking countries.
Article • Support for clinicians beyond initial diagnosis
Enhancing breast imaging with AI
Artificial intelligence has a critical role to play in supporting clinicians beyond the initial breast cancer diagnosis. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting in Aberdeen, Scotland, Professor Gerald Lip outlined how AI can enhance the performance of modalities such as ultrasound and MRI in supporting clinicians as they plan and deliver treatment for patients.
Article • From ablation to neuromodulation
The new era of functional radiosurgery
Functional brain radiosurgery is an application of stereotactic radiosurgery (SRS), representing its newest clinical field. It is a precise, non-invasive medical technique using focused ionising radiation to precisely target specific brain structures to modulate brain function for neurological disorders, psychiatric conditions, or intractable pain. The technology offers “precision without…
News • Liquid biopsy screening tool
AI metabolomics platform to advance pancreatic cancer early diagnosis
Pancreatic cancer remains a diagnostic challenge, due to unspecific early symptoms and lack of effective screening tools. A novel AI metabolomics platform could help overcome these issues.
News • Lymphovenous bypass
A surgical treatment for Alzheimer's disease?
A small but growing body of evidence suggests that a minimally invasive surgical procedure called lymphovenous anastomosis (LVA) might be an effective treatment for Alzheimer's disease.
News • At least 18 years of reduced risk
Cervical cancer: study confirms long-term protection from HPV vaccination
Vaccination against human papillomavirus (HPV) reduces the risk of cervical cancer for at least 18 years, according to a new study. There were no signs of waning protection over time.
News • Microbial interactions
Gut bacteria interactions show promise as health and disease marker
To better distinguish between healthy and diseased gut microbiomes, scientists have created an index that tracks microbial behavior and signals conditions such as colorectal cancer.
News • Biomarker-agnostic detection
Electronic nose uses AI to “smell” ovarian cancer
Using machine learning, researchers have trained an electronic nose to detect early signs of ovarian cancer in the blood. The method could eventually be used to find many different cancers.
News • (B)eating cancer
Bacteria to consume tumours from the inside out
A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.
News • Study shows stage-specific outcomes
Screening increases survival rate – even in advanced breast cancer
Study shows women with stage IV breast cancer detected through screening have a 60% chance of survival ten years after diagnosis – compared to under 20% for those not detected through screening.
News • Proof-of-principle study
Ultra low-field MRI shows promise for breast cancer screening
New research shows that using ultra-low field (ULF) MRI for breast imaging could offer an alternative to existing breast cancer screening methods and may reduce barriers to screening.
News • New sequencing technique
Classifying pediatric brain tumors with liquid biopsy and AI
Clues in the CSF: Researchers have developed the first high-precision method that can theoretically diagnose common brain tumors in children and adolescents without surgery.
News • Cancer “chronotherapy”
Beating cancer by the clock: Why the time of day matters for radiotherapy
Radiotherapy is more effective when administered at the right time of day, according to new research. This discovery opens the door to cancer “chronotherapy”, the researchers hope.
News • AI detects unseen connection
Insulin resistance identified as risk factor for cancer
Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.
News • Alternative to anaesthesia
Mindfulness might be the key for more effective endoscopies
Less cancers missed, fewer complications: Mindfulness enables procedures to be done to a higher standard in awake patients than is currently possible under general anaesthesia or sedation.
Article • Digital pathology and AI
Finding new biomarkers to match the biological complexity of cancer
Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…
Article • The “invisible” population
Breast screening blind spot: Why transgender patients are falling through the cracks
Transgender patients are largely invisible in breast cancer screening statistics – and many never receive an invitation to participate in screening programmes. Guidelines exist, but awareness among referring physicians remains low. Experts say radiology departments are best positioned to lead the change by creating inclusive environments and actively reaching out to this underserved population.…
News • Research on metastasis mechanism
How ovarian cancer hijacks abdominal cells as an invasion force
Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.
News • CTNNB1 in focus
Mutation strength may hold key to personalized cancer treatment
Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.
News • Sharper images, less radiation
Lung cancer management: Photon-counting CT outperforms conventional CT
A study of 200 lung cancer patients shows photon-counting CT cuts radiation by 66% and contrast agent by 27% - while delivering sharper images and better tumor detection than conventional CT.
News • Fungal effect on skin cancer
Candida albicans increases melanoma aggressiveness, study shows
Reseachers show how Candida albicans – a fungus living in our body – can make melanoma more aggressive. The results pave the way for antifungal therapies to complement skin cancer treatments.
News • Low-power architecture
Portable ultrasound sensor to enable earlier detection of breast cancer
MIT researchers have developed a miniaturized ultrasound system that could make it easier for breast ultrasounds to be performed more often, either at home or at a doctor’s office.
Article • From observation to action
The rise of agentic AI in pathology
Computational pathology is becoming increasingly important in helping deliver precision medicine to a wider range of patients. Experts at the 37th European Congress of Pathology in Vienna discussed how algorithms can optimise laboratory workflows, generate stronger evidence for molecular tumour boards, and enhance clinical trial design.
News • Two tracers, one target
Dual PET approach for personalized head and neck cancer treatment
Beyond "one-size-fits-all": A new strategy that combines two types of PET scans can guide personalized radiotherapy for head and neck cancers, according to new research.
News • PRO in oncology
Giving patients a voice: How self-reported data improves cancer treatment
Integrating the patient’s voice: A new study shows access to patient-reported outcome (PRO) data improves the consistency of the evaluation of treatment-related side effects in patients with cancer.
News • Soft tissue ablation
Adapting eye-laser technology to remove cancer
Scientists have shown that a type of laser similar to the one currently used in routine eye surgery could one day help surgeons remove unwanted tissues, such as tumours, with unprecedented accuracy.
News • Exploring metastatic potential
AI predicts risk of cancer metastases
Why do some tumours spread while others remain localised? Using colon cancer cells, scientists pinpointed the criteria that influence metastasis risk, and identified a way to assess its probability.
News • Gastric multi-regional assembloid
Lab-grown mini-stomachs to boost understanding of rare diseases
A new type of lab-grown organoid that mimics the behaviour of a human stomach could boost the understanding of rare gastric diseases, researchers say.
News • Plasma protein profiling
Blood test spots cancer in patients with unspecific symptoms
Non-specific symptoms such as fatigue, pain or weight loss can be caused by cancer, another serious condition or something completely harmless. A blood test can help provide relevant information.
News • Systemic mechanism discovered
Chemotherapy rewires gut bacteria to curb metastasis
Chemotherapy does more than kill cancer cells: It reshapes the gut microbiome, making the body less permissive to metastasis. This finding opens new avenues for adjuvant strategies.
News • Anthracycline cardiotoxicity
Common chemo drug increases risk of heart damage, study finds
A widely used chemotherapy drugs used in cancer treatments can cause heart damage, new research shows. This could be used to adapt treatment regimens - especially in patients with high blood pressure.
News • Disease tolerance and infection pathogenesis
Different age, same infection treatment? Not a good idea, study finds
Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
News • Exploring the mutational landscape
Colorectal cancer: DNA testing unlocks hereditary clues
DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal cancer, research finds. This leads to better diagnostics and treatment.
News • Focus on tumor STAT1 acetylation
How cancer cells learn under pressure to evade immunotherapy
Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.
Article • Implementation of clinical artificial intelligence
One AI, one radiologist: How a Swedish hospital beat breast screening backlogs
When radiologists at Stockholm's Capio Sankt Görans Hospital began working evenings and weekends to clear mounting backlogs, it became clear that something had to change. The solution? Replacing one of the two radiologists traditionally assigned to read breast cancer screenings with artificial intelligence (AI). The results: fewer false positives, more cancers detected, and radiologists…
News • Phase III trial
Proton therapy shows survival benefit for patients with head and neck cancers
A new study shows a significant survival benefit for patients with oropharyngeal cancers treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).
Article • Personalised medicine
Gene-editing technologies: from lab to patient
Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
News • Acellular dermal matrix for breast reconstruction
Injectable breast ‘implant’ as alternative to surgery
Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.
News • Clinically validated framework
AI helps detect kidney cancer faster
A novel machine-learning-based solution analyses CT images and helps radiologists detect both malignant and benign lesions in the kidney more quickly and reliably.
News • Tissue sample analysis
Demographic bias creeps into pathology AI, study finds
A sample of inequality: A new study shows that AI models can infer demographic information from pathology slides, leading to bias in cancer diagnosis among different populations.
News • Prevalence, changes and associated factors
How to reduce the risk of head and neck lymphedema after radiotherapy
Researchers have discovered that low physical activity is associated with a higher risk of lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition.
News • New treatment approach
Ultrasound 'softens up' tumors before chemo
To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.
News • Adaptive re-planning
Repurposed radiotherapy scans to guide prostate cancer treatment
Radiotherapy is effective against prostate cancer but can cause side effects. Using AI, scientists found that images originally taken to help position patients could also predict rectal bleeding.
Article • Advancing risk stratification
AI in breast cancer screening: From mammograms to personalised risk prediction
Artificial intelligence is reshaping how clinicians identify women at higher risk of breast cancer – and may soon guide decisions on supplemental screening and treatment. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting in Aberdeen, Scotland, two experts presented their latest findings on AI-driven risk stratification and response prediction.
News • Genetic risk-based approach
Enhancing breast cancer screening to save young women’s lives
Breast cancer screening for women under 50 isn't cost-effective – yet 1 in 5 diagnoses occurs in this age group. A new study suggests a personalised approach that could change this equation.
News • Differentiation after radiotherapy
Brain tumour or radiation necrosis? AI can tell them apart
A novel AI-based method can distinguish between progressive brain tumours and radiotherapy-induced necrosis on advanced MRI. This could help clinicians more accurately identify and treat the issues.
Article • Overlooked and underserved populations
Breast imaging for male and transgender patients: bridging the knowledge gap
Breast imaging for male and transgender patients remains an under-researched field with significant gaps in guidelines and clinical practice. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting, experts presented findings from a pan-European survey on male breast imaging and announced plans for a similar initiative focusing on transgender patients.
News • CAR-T and BITEs
At-home monitoring safely cuts hospital time after T-cell redirecting therapy
After T-cell redirecting therapies, patients are typically hospitalized for several days to watch for side effects. New research shows that these patients can safely be monitored at home.
News • AI-assisted diagnostics
Two Dutch hospitals implement AI for lung nodule detection on chest X-rays
Two major Dutch hospitals, Catharina Ziekenhuis in Eindhoven and University Medical Center (UMC) Utrecht, are integrating artificial intelligence (AI) from Qure.ai into their chest X-ray workflows.
News • Malignant melanoma
Immunotherapy for skin cancer: when less is more
New immunotherapies are effective against skin cancer, but they can cause serious side effects. New insights suggest that a lower dosage may lead to better outcomes and longer survival.
News • Lung cancer CT notification
Breast cancer: Keep CALM – and coordinate your screenings
Many women over 50 schedule mammograms for breast cancer but miss out on CT lung cancer screenings they're also eligible for. Targeted outreach coul help change this, a new study shows.
News • Unintended effects
Telling women that they have dense breasts may do more harm than good
Should women be told about their high breast density as part of mammography screening? While this may sound like an obvious choice, a new study warns of unintended effects.
News • Insights on IDH mutated gliomas
Brain cancer: why early treatment is not always the best course
IDH mutated gliomas are slow-growing brain tumors with a relatively good prognosis. A new study shows that many patients reveal measurable cognitive impairment in the first year after treatment.
News • Appeal for earlier screening approaches
Alarming number of invasive breast cancers in younger women
Breast cancer – including aggressive variants – are surprisingly common in younger women, a new study shows. The findings strengthen the case for earlier, risk-tailored screening, the authors say.
News • Benefits for survival and employment
Breast cancer: study explores economic aspects of radiotherapy
While saving lives remains the primary goal, a new study explores how radiation therapy also helps breast cancer survivors return to work. Policymakers should factor this in, the researchers argue.
News • Attenuation contrast und dark field
One X-ray, three images: new method unveils hidden features
Researchers developed an X-ray imaging method capable of revealing hidden features in a single shot. This could advance cancer detection, disease monitoring, security screening and material analysis.
News • Bacteria-eating viruses
New phages spark hope against hospital superbug
A team of researchers comprehensively catalogued a new collection of bacteria-eating viruses called phages. These phages could be used to combat Klebsiella pneumoniae - a serious threat in hospitals.
Article • On a shoestring budget
Bridging the resource gap for pathology in developing countries
Delivering a pathology service in resource-constrained locations and developing countries remains a challenge. Cost is a significant barrier, as is the availability of equipment, trained staff and technical and IT support can also hinder a desire from clinicians and pathologists to give their patients a high level of service to help their diagnosis and recovery. The subject was tackled in a…
News • In vitro disease models
'Intrepid' research to advance cancer therapies
A major new initiative aims to enable the development of advanced, specific and highly reproducible human in vitro models for greater understanding of disease and the acceleration of new medicines.
News • Balloon-Assisted Bronchoscope Delivery
New technique opens route to previously unreachable lung tumors
Researchers have engineered a novel technique that uses a small balloon to gently widen the airways, and overcome the physical limitations of conventional bronchoscopy to reach deep lung tumors.
News • Ultrasound-guided gene therapy
New approach for targeted seizure control without surgery
New hope for patients with neurological diseases: A combination of focused ultrasound and gene therapy enables targeted, nonsurgical control of seizure-relevant brain regions.
News • New targetable driver of growth found
Thyroid gland: unexpected key to prostate cancer treatment
An international research team has discovered a promising new therapeutic approach for aggressive prostate cancer – in the thyroid gland.
Article • Utilizing new strengths, fixing old weaknesses
Ultrasound update for organ imaging
Has organ imaging using ultrasound arrived at the same level as cross-sectional imaging? At the annual conference of the German Society for Internal Medicine (DGIM), PD Dr Corinna Trenker presented new technological developments and their diagnostic significance. Despite numerous innovations such as multiparametric protocols and AI support, she made it clear that the human factor remains one of…
News • Dermatology mnemonic
“A–F Think MF”: a simple memory tool for early recognition of rare lymphoma
Just like the “ABCDE” mnemonic for melanoma awareness, researchers hope their diagnostic tool will transform how doctors approach persistent rashes, reminding them to consider lymphoma sooner.
News • Synthetic peptide hydrogels
Bioengineered bone marrow model advances leukaemia research
Using a bioengineered bone marrow model, researchers were able to provide key new information on the efficacy and safety of CAR T-cell therapy for acute myeloid leukaemia (AML), the most common leukaemia in adults.
News • Dual-barrier tumours
How colorectal cancer evades immunotherapy (and what to do about it)
Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.
News • Targeted drug activation
Ultrasound-triggered chemotherapy to reduce side-effects
Researchers explore how ultrasound waves can be used to activate chemotherapy drugs only in targeted areas, offering a new path toward safer, more effective cancer treatment.
News • Early thoracic malignancy screening
Developing a breath test for lung cancer with biosensors and AI
A biosensor that identifies volatile organic compounds (VOCs) in exhaled breath could be used in conjunction with AI to detect various thoracic cancers including lung cancer.
Article • Risk stratification initiatives in Europe and UK
The future of breast imaging: a date with density
About 60% women in Europe enrolled in a national breast cancer screening programme who have a screening mammogram can feel reasonably confident that radiologists will be able to diagnose early-stage breast cancer. But what about the 30% categorised as having dense breasts, and the 10% who have extremely dense breasts? At the 2025 SBI (Society of Breast Imaging) Breast Imaging Symposium held in…
News • Link between Covid, flu, HIV and CVD
Viral infections may increase the risk of cardiovascular disease
After a bout of influenza or Covid, the risk of heart attack or stroke may rise dramatically, and chronic infections may increase the long-term risk of serious cardiovascular disease events.
Article • Reshaping GI cancer care
Pathologists at the heart of precision oncology
Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…
News • Transformer-based learning from radiomics and clinical data
New AI model improves prediction of breast cancer recurrence
An international team has developed an AI model that brings together medical imaging data and clinical information to calculate the risk of breast cancer tumour recurrence more accurately.
News • Eco-friendliness and confidence
Patients open to more sustainable treatments, study finds
Many doctors shy away from discussing the aspect of a treatment's sustainability with their patients, expecting a negative reaction. Now, a new study suggests that these fears may be unfounded.
News • Research reveals infiltrating microbes
How bacteria in tumors drive treatment resistance in cancer
Researchers have discovered a previously unknown mechanism that explains how bacteria within a tumor can drive treatment resistance in patients with oral and colorectal cancer.
News • Radiation-induced cognitive decline
New approach to protect the brain during radiation therapy
Researchers identified a targeted way to protect the brain from harmful side effects of cranial radiation therapy, potentially preserving the quality of life for millions of brain cancer survivors.
News • New imaging solution
PSMA PET to detect prostate cancer recurrence
A novel imaging solution, called PSMA PET scanning, can more effectively detect the recurrence of prostate cancer compared to standard methods, and is associated with improved survival outcomes.
Article • Management of escalating imaging workload
Breast cancer screening: growing with the challenge
Rising attendance in mammography screening programmes attest to the fact that women understand the importance of early breast cancer detection. However, the resulting workload increase is a growing challenge for many women’s imaging centres. At the 2025 SBI (Society of Breast Imaging) Symposium, breast imaging specialist Stamatia V. Destounis, MD, discussed her practice’s coping strategies.
News • Focus on Helicobacter pylori
Towards a vaccine against ulcers, stomach cancer
Scientists are on the way to finding a vaccine to fight off Helicobacter pylori - a bacterium found in over 60% of people - possibly preventing stomach ulcers and lowering the risk for stomach cancer.
News • Nuclear imaging
Prostate cancer: High-speed whole-body SPECT tracks tumor evolution
A new type of SPECT imaging provides strong prognostic information to guide prostate cancer treatments according to tumor evolution, significantly impacting patients' overall survival.
News • Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Blood test for ME/CFS unveiled
Chronic fatigue (ME/CFS) affects millions worldwide, but is poorly understood and has long lacked reliable diagnostic tools. Now, a new blood test claims to diagnose the condition with 96% accuracy.
News • Study explores clinical potential of WGS
Whole genome sequencing could help 15,000 breast cancer patients per year, study finds
Breast cancer claims around 670.000 lives each year. Now, researchers propose that whole genome sequencing (WGS) could help many patients find better treatments or match them with clinical trials.
News • Precision Oncology Ireland (POI)
Ireland’s largest ever cancer research programme enters next phase
Precision Oncology Ireland (POI), a €28M cancer research programme uniting universities, charities and industry to develop tailored diagnostic and therapeutic solutions, has now entered phase 2.
News • Weight loss and diabetes medication
GLP-1 agonists may interfere with cancer imaging, new study finds
GLP-1 receptor agonists are widely prescribed for individuals with diabetes and weight loss. However, these medications may adversely affect the interpretation of cancer imaging, new research finds.
Article • Personalizing stroke care
Advancing genomic medicine from promise to practice with digital technology
Stroke patients in four NHS hospitals are now receiving genetic tests that determine whether a commonly prescribed drug will work for them – a breakthrough that could transform treatment for millions. Digital approaches are spearheading a drive to help make genomic medicine part of everyday care. The role of digital tools was a central theme at the HETT (Healthcare Excellence Through…
News • Quantitative analysis of the mammary ductal tree
Calculating breast health with branching math
Researchers have developed a tool to quickly quantify changes in the branches of mouse mammary glands. This could one day be used to detect early warning signs of breast cancer.
News • Peripheral immune tolerance
Immune system researchers receive Nobel Prize 2025 in Medicine
The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.
News • AML targetable immune escape mechanism
How leukemia cells trick the immune system
Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.
News • Focus on adipose tissue metabolism
Endometrial cancer: visceral fat may drive aggressiveness
Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.
News • Study shows widespread disruption
Glioblastoma: damage beyond the brain
Scientists have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body’s immune response.
News • Call for more informed decision
Hormone replacement therapy after breast cancer: a risk worth taking?
Breast cancer survivors are often discouraged from undergoing hormone replacement therapy (HRT) to alleviate menopause symptoms. Now, new research paints a more differentiated picture.
Interview • An interview with the President of JFR 2025
What the clinic does not say
This year, the Journées Francophones de Radiologie (JFR) will carry a clinical ambition as simple as it is essential: to shine a spotlight on those who are often overlooked. Under the presidency of Professor Mathieu Lederlin, thoracic radiologist at Rennes University Hospital, vulnerable patients will be at the heart of the annual meeting of the French Society of Radiology that will unfold…
News • Focus on methylation changes
Detecting tumour DNA in urine to identify bladder cancer
Researchers from the University of Birmingham’s Bladder Cancer Research Centre have found a new way of detecting tumour DNA in urine to identify bladder cancer.
News • Microbiome
Fatty acids fuel cancer-promoting gut bacteria
TU München researchers discover how chronic cellular stress changes gut microbiome composition, promoting cancer development through altered lipid metabolism.
News • Pediatric Radiology
Medical imaging raises blood cancer risk in young patients
Study of 3.7 million children reveals small but significant increased risk of blood cancers from medical imaging radiation, with CT scans posing highest risk
News • Research
Stuttgart researchers enhance CRISPR for cellular analysis
University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.
News • Machine learning analysis
‘Two-for-one’ screening uses mammograms to predict heart disease in women
Using AI to help detect one of the leading killers of women worldwide: A new machine learning model can successfully predict heart disease risk in women by analysing mammograms.
News • Estimation of nodule malignancy risk
Lung cancer screening: AI to reduce false positives
Misinterpreting the malignancy risk of lung nodules often results in high false-positive rates, unnecessary follow-ups, increased patient anxiety and healthcare costs. A new study suggests that AI can fix this.
News • Hurdles for AI implementation
What's holding back the digital transformation of NHS healthcare
Digital transformation, including AI, is key to improving healthcare services - but this may be easier said than done: A new UK study identifies hurdles for AI implementation in NHS hospitals.
News • Kinetic analysis of therapeutics
How boron may point the way to better therapies for head and neck cancer
A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumours in some cancers.
News • Response to changes in pH levels
‘Artificial cartilage’ releases drugs to counter arthritis flare-ups
A squishy new ‘artificial cartilage’ material could improve arthritis treatments by releasing anti-inflammatory drugs in response to a flare-up.
News • EGFR-mutated non-small cell lung cancer
NSCLC: Surgical combination therapy may prolong disease control
In metastatic EGFR-mutated non-small cell lung cancer (NSCLC), targeting residual disease through surgery can extend the benefits of EGFR TKI therapy beyond standard monotherapy, a new study finds.
News • Evaluating tadiotheranostic targets
Endometrial cancer: new markers for PET imaging
Researchers explored two promising new biomarkers as potential radiotheranostic targets for endometrial cancer. This could help identify patients who are likely to respond to targeted therapeutics.
News • Focus on health-related quality of life
Pushing for a more patient-centered approach to advanced cancer care
Currently, cancer treatment evaluation focuses heavily on survival outcomes, but doesn't adequately consider how treatments affect quality of life. A new policy review aims to change this.
News • Reliability of mammography analysis
AI still misses 14% of advanced breast cancer cases, study finds
AI may be effective at detecting advanced breast cancer in mammograms, but current models still lack reliability. New research from Korea suggests that up to 14% of invasive cases are missed.
Article • AI-powered prediction
Machine learning identifies cardiotoxicity risk in breast cancer patients
Researchers have developed a machine learning algorithm that uses cardiac MRI images to help identify breast cancer patients who may be at risk of cardiotoxicity during cancer treatment. The research, led by cardiologist Dr Paaladinesh Thavendiranathan, was presented at the European Society of Cardiology's Cardio-Oncology Conference in Florence in June.
News • Prediction of treatment sensitivity
Personalising prostate cancer treatment through molecular testing
A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.
News • Optical technique
AI-assisted autofluorescence imaging to early detect colorectal cancer
An advanced imaging method that uses the natural glow of tissues could help detect subtle differences in the tissue’s biochemistry, offering a way to earlier detect colorectal cancer via endoscopy.
News • Study on deliberate ignorance
Why one in three people avoid information about their own health
One in three people do not want to know about serious illnesses—even if they might be affected themselves. A new review study explores the reasons for this deliberate ignorance.
Article • From H&E to multiplex
Self-learning AI: a boost for digital pathology
Self-learning artificial intelligence approaches are offering a number of advantages for digital pathology when compared to established AI options. The benefits, which range from greater speed and capacitive flexibility to ‘wholly interpretable’ analyses, were outlined at the Digital Pathology and AI Congress in London.
News • Patient-specific dose quantification
New method to protect blood during radiotherapy
A newly developed method to accurately quantify how much radiation is absorbed by the blood during cancer treatment could lead to more personalised, preventive, and safer radiotherapy.
News • Implicit information
In-depth AI microbiome analysis reveals colorectal cancer
Scientists developed an AI-based approach to diagnose colorectal cancer from different microbial subgroups in the gut microbiota – a non-invasive and low-cost alternative to colonoscopy screening.
Article • Societal and ethical impacts explored at ECR 2025
How AI is transforming radiology – and radiologists
Patient communication facilitated by chatbots, image quality optimized by machine learning: Artificial intelligence (AI) is entering radiology at breakneck speed, transforming the specialty almost beyond recognition. So, how will the future of diagnostic imaging under AI look like, and which role will humans still play in it? At the ECR congress in Vienna, experts explored the societal and…
News • Discovery of tumour indicating morphological changes
Prostate cancer: AI finds changes missed by pathologists
Men assessed as healthy may still have an early form of prostate cancer. Using AI, researchers found signs that were missed in more than 80% of samples of men who later developed cancer.
News • Research on Antrodia cinnamomea
Promising fungal compound to fight cancer and inflammation
Studies have found that natural polysaccharides from a medical fungus endemic to Taiwan can not only effectively inhibit inflammation, but also fight the proliferation of lung cancer cells.
News • Fluorescent 18F-PET imaging
Dual-mode PET tracer lets surgeons see – and hear – prostate cancer
Tracer molecules serve to provide visual guidance in nuclear medicine, but a new molecule could give surgeons additional audio cues to help them locate prostate cancer tumors and metastases.
News • SEBS material safety
New artificial heart valve passes long-term test in animals
An artificial heart valve made from SEBS, a new type of highly durable and biocompatible plastic, could be a step closer to use in humans, following a successful long-term safety test in animals.
News • Endoscopic magnetometer
Finding cancer with diamond sensors
Researchers report they have built a new non-toxic and non-radioactive handheld device that uses the unique properties of diamonds to diagnose metastasized breast cancer.
News • Breast cancer screening
Mammography: Hybrid reading to overcome AI overconfidence
Mammography image interpretation AI models are unreliable – but so are human readers. A new hybrid strategy could reduce radiologist workload by 38% without compromising diagnostic efficacy.
News • Neural anticipation of infection
Virtual health threats trigger real immune response
The mere fact of being exposed to a sick avatar in a virtual reality environment triggers a measurable immune response in humans, a multidisciplinary research team discovered.
News • Nasopharyngeal carcinoma detection
Virtual MRI for contrast-free NPC tumour imaging
Gadolinium-based contrast agents enhance visibility but also pose a significant health risk. A new AI-powered virtual MRI imaging technique is designed to offer a safer diagnostic approach.
News • Mammogram assessment
AI can replace second radiologist in breast cancer screening, study finds
More clinically relevant tumors detected at an earlier stage and at lower costs: New research finds that AI can replace the second radiologist in the Dutch breast cancer screening program.
News • Adenoma detection rate
Using AI support makes endoscopists lose skills, study finds
AI tools for adenoma polyp detection are designed to help increase the accuracy of colonoscopies. However, a new study finds that using AI may lead to loss of detection skills in health professionals.
News • Risk prediction
Kidney failure: frail CKD patients might fall under the radar
New research suggests that KFRE, a common prognostic tool to predict kidney failure, could underestimate the risk for individuals with chronic kidney disease (CKD) who also have frailty.
News • Review explores bacterial impact
Vaginal microbiome holds untapped potential for women's health
The vaginal microbiome is a largely overlooked area of medicine that could dramatically improve outcomes for common infections, infertility and even cancer for millions of women, a new review finds.
News • Chronic obstructive pulmonary disease
One step closer to COPD population screening
A multicenter study involving leading hospitals across Spain, has confirmed that people with COPD show altered levels of specific metabolites in their blood.
News • Microsatellite instability
Predicting tumor MSI status for precision cancer treatments
Microsatellite instability-high (MSI-H) tumors are associated with better clinical outcomes. A novel AI model for accurate MSI prediction could help battle gastric and colorectal cancers.
News • Goodbye to the needle
Replace injections with pills? New technology could make it happen
Some medications can only be taken as an injection, which is often painful, unpleasant and inconvenient for patients. A new transport system could make it possible to swap these injections for pills.
Article • Blood-based biomarkers under scrutiny
BBB testing for universal Alzheimer’s screening? It’s complicated
Do laboratory tests using blood-based biomarkers (BBB) represent the next type of universally recommended screening tests for Alzheimer's disease (AD)? Experts curb the high expectations for this type of diagnostic tool.
News • Patient involvement enables research
Tumor vesicles as a promising biomarker for early cancer detection
Tumor vesicles may serve as early indicators of cancer and help monitor the effectiveness of treatments. Now, researchers discovered a new way to detect these vesicles.
News • Predictive phenotypes
Ovarian cancer: new insights into immune landscapes
Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.
News • Risk of misclassification
Prostate cancer: why “low-grade” might not be “low risk”
Classifying prostate cancer as “low-grade” could create a false sense of security and delay definitive treatments. A new study shows that the biopsy grade alone can paint an incomplete picture.
News • Respiratory viruses wake up cells in the lungs
How Covid-19 and flu infections revive dormant breast cancer
Common respiratory infections such as influenza and Covid-19 can awaken dormant breast cancer cells that have spread to the lungs, setting the stage for new metastatic tumors, new research finds.
News • Mitochondria-derived nuclear ATP surge
Pressed to the limit: New study explores cancer cell defense mechanism
How cancer cells survive the journey through the body to form metastases is still poorly understood. New insights into how cells survive intense physical stress could pave the way for new treatments.
News • Rapid exosome isolation and detection
Researchers develop at-home skin patch test for melanoma
Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.
News • Position and completeness assessment
3D CT analysis benefits liver tumor ablation
By analyzing CT images with 3D software, researchers demonstrated that small liver tumors can be successfully treated using ablation. This could enable more confident use of ablation treatments.
Article • Sustainable workflows
Designing the laboratory of the future
Laboratories across Europe are embracing sustainability through paperless workflows and automation. In this guest article, Gavin Hirst, Clinical Flow Cytometry Account Manager at Beckman Coulter Life Sciences, shares his thoughts on how digital transformation and eco-friendly practices not only advance climate goals but enhance efficiency, allowing scientists to focus on critical research rather…
News • Lifetime risk thresholds for mastectomy
Breast cancer: When should clinicians offer surgical options?
When should preventive mastectomy be offered for women at higher risk of breast cancer? A new evaluation model defines thresholds at which risk reducing surgery should be recommended.
News • Enhanced imaging and surgical guidance
Fluorescent bacteria light up tumors like a neon sign
A new, bacteria-based contrast agent illuminates tumors like a neon sign during surgery, enabling more precise resection and reducing the risk of recurrence.
News • Beyond the mammogram
Cracking the code of breast calcifications – with geology?
Dense calcifications are common in breast tissue, but not every finding in a mammogram is a precursor of cancer. New insights could lead to fewer benign biopsies and guide therapeutic development.
News • Electrical impedance spectroscopy
EIS shows promise to advance cancer cell monitoring
Through quantitative real-time monitoring of cell spatiotemporal dynamics, or cell changes over time, electrical impedance spectroscopy (EIS) could be used to predict cancer growth.
News • Proteomic-based score
AI measures tumor ‘stemness’ to predict cancer aggressiveness
A new AI-based tool measures cancer aggressiveness by analyzing the ‘stemness’ of tumors – their similarity to pluripotent stem cells. This could pave the way for new therapies.
