News • mRNA-based strategy
Cystic fibrosis: new study identifies gene therapy
Now, a new study identified a gene therapy for individuals with cystic fibrosis (CF) caused by a specific mutation and for whom there was no treatment available until now.
Search for: "genetic disease" - 250 articles found
News • Focal cortical dysplasia
Lab-grown mini-brains shed light on childhood epilepsy
Why does the same genetic mutation cause FCDII in some patients but not in others? Researchers developed organoids to model a brain malformation responsible for drug-resistant epilepsy in children.
Article • Experts explore often-overlooked patient group in oncology
A rising tide: cancer in young adults
For a young adult, a cancer diagnosis hits different: a more aggressive disease course, greater disruptive potential, longer survivorship. Yet most healthcare institutions seem poorly prepared for this growing patient group. A plenary session at the NCCN 2026 Annual Conference examined a striking shift in modern oncology: the rising incidence of cancer in adolescents and young adults (AYA).
News • Genetic CAD risk scores
Researchers link diabetes subgroups to coronary heart disease risk
Researchers have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease.
News • Cryo-electron tomography
3D microscopy reveals how tick-borne virus replicates
Tick‑borne encephalitis is one of the most dangerous viral diseases spread in Europe. Researchers have discovered how the viruses replicate inside cells, paving the way for future treatments.
News • Medical computer models
Digital twin hearts succeed in arrhythmia trial
Working with “digital twins” of patients’ hearts, doctors improved cardiac ablation outcomes for patients with life-threatening arrythmias.
Sponsored • New study data presented at ECR 2026
Redrawing contrast dose limits in MRI
At this year’s European Congress of Radiology (ECR) in Vienna, Bayer presented new data on a contrast agent that could transform MRI imaging: gadoquatrane, which requires up to 60% less gadolinium than previous standard macrocyclic preparations whilst maintaining the same diagnostic accuracy. Prof. Hubertus Pietsch, Head of MRI & CT Contrast Agent Research at Bayer and one of the key…
News • Neuro-oncology
Simple blood test could detect glioblastoma in the future
Glioblastoma is notorious for late diagnosis, rapid progression, resistance to treatment and its biological complexity. A new experimental method could help detect this deadly type of brain cancer.
News • Common comorbidity
Researchers find genetic link between type 2 diabetes and hypertension
Type 2 diabetes and high blood pressure share a genetic link, new research from the UK and France shows. People with one condition are more likely to develop the other.
News • AI detects unseen connection
Insulin resistance identified as risk factor for cancer
Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.
News • Research on metastasis mechanism
How ovarian cancer hijacks abdominal cells as an invasion force
Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.
News • CTNNB1 in focus
Mutation strength may hold key to personalized cancer treatment
Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.
News • Plasmid-specific ecological adaptation
How antimicrobial resistance spreads from gut bacteria to hospital superbugs
Researchers have uncovered how a high-risk class of genetic vectors can efficiently spread antibiotic resistance within the gut, enabling even highly virulent bacteria to acquire drug resistance.
News • Gastric multi-regional assembloid
Lab-grown mini-stomachs to boost understanding of rare diseases
A new type of lab-grown organoid that mimics the behaviour of a human stomach could boost the understanding of rare gastric diseases, researchers say.
News • Neurosciences
New insights on the onset of Huntington's disease
Why does Huntington’s disease begin at very different ages? Using advanced AI techniques, neuroscientists from the University of Barcelona found a way to better answer this question.
News • Exploring the mutational landscape
Colorectal cancer: DNA testing unlocks hereditary clues
DNA analysis of colorectal polyps provides important additional information on the development of these polyps and colorectal cancer, research finds. This leads to better diagnostics and treatment.
News • Intragenic complementation
Rare disease genetics: two wrongs actually can make a right, study shows
Scientists have overturned a long-held belief in genetics: that inheriting two harmful variants in the same gene always worsens disease. Instead, this can actually restore normal protein function.
Article • Personalised medicine
Gene-editing technologies: from lab to patient
Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
News • Between the heart and the brain
Why cardiovascular disease and depression often develop together
Cardiovascular disease and depression do not co-occur by chance; the TO_AITION project aims to enable earlier diagnosis of comorbidity, better risk prediction and personalised treatment strategies.
News • When good bacteria fight back
Klebsiella strain to protect against IBD gut infections
New research shows that a harmless strain of Klebsiella – discovered by chance in laboratory experiments – can eliminate infections and reduce gut inflammation in inflammatory bowel disease (IBD).
News • Genetic risk-based approach
Enhancing breast cancer screening to save young women’s lives
Breast cancer screening for women under 50 isn't cost-effective – yet 1 in 5 diagnoses occurs in this age group. A new study suggests a personalised approach that could change this equation.
News • ‘Reverse genetics’ system
New approach to norovirus vaccine and drug development
Researchers from Osaka have developed a simple and efficient system for understanding the functions of specific norovirus genes, providing new avenues for developing antivirals and vaccines.
Article • Overlooked and underserved populations
Breast imaging for male and transgender patients: bridging the knowledge gap
Breast imaging for male and transgender patients remains an under-researched field with significant gaps in guidelines and clinical practice. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting, experts presented findings from a pan-European survey on male breast imaging and announced plans for a similar initiative focusing on transgender patients.
News • New insights on nosocomial pathogen
Research reveals ‘hidden movement’ of Pseudomonas aeruginosa
Pseudomonas aeruginosa, a hospital-acquired bacterium that causes serious infections, can move from the lungs to the gut inside the same patient, raising the risk of sepsis, new research reveals.
News • Exploration of novel biomarkers
Depression: not just a disease of the mind
Depression is not only a disease of the mind or the brain, a new study finds: a research team has revealed deep connections to abnormalities in the body's overall immune response.
News • Sex-specific dysregulation
Why women are three times more likely to get severe long Covid
New research reveals why women with long Covid — especially those who develop chronic fatigue syndrome — tend to experience more severe and persistent symptoms than men do.
News • Ultrasound-guided gene therapy
New approach for targeted seizure control without surgery
New hope for patients with neurological diseases: A combination of focused ultrasound and gene therapy enables targeted, nonsurgical control of seizure-relevant brain regions.
News • New targetable driver of growth found
Thyroid gland: unexpected key to prostate cancer treatment
An international research team has discovered a promising new therapeutic approach for aggressive prostate cancer – in the thyroid gland.
News • Selective degradation of neurons
ALS: Key mechanism behind motor function loss discovered
Why does amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, attack motor neurons, the cells that control body movement, while others are spared? A new study may have found an answer.
Sponsored • Solutions aligned with global clinical market needs
Innovative biomedical solutions from Taipei presented at MEDICA 2025
With Taipei City Government's support, six Taipei companies will showcase innovative biotech and medical device solutions at MEDICA 2025 (Nov 17–20, Düsseldorf), advancing healthcare with speed and precision.
News • Proteins for personalized treatments
Tracking Duchenne muscular dystrophy with blood biomarkers
Newly discovered blood biomarkers may offer new options to track Duchenne muscular dystrophy (DMD) in a less invasive way than physical tests or biopsies. This could support more tailored treatments.
News • Radiation-induced cognitive decline
New approach to protect the brain during radiation therapy
Researchers identified a targeted way to protect the brain from harmful side effects of cranial radiation therapy, potentially preserving the quality of life for millions of brain cancer survivors.
News • Genomic care in the NICU
World record for fastest whole genome sequencing paves the way for POCT usage
In the NICU, a few hours can mean the difference between unnecessary procedures and targeted, life-saving treatment. A new speed record for WGS opens new diagnostic possibilities.
News • Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Blood test for ME/CFS unveiled
Chronic fatigue (ME/CFS) affects millions worldwide, but is poorly understood and has long lacked reliable diagnostic tools. Now, a new blood test claims to diagnose the condition with 96% accuracy.
News • Study explores clinical potential of WGS
Whole genome sequencing could help 15,000 breast cancer patients per year, study finds
Breast cancer claims around 670.000 lives each year. Now, researchers propose that whole genome sequencing (WGS) could help many patients find better treatments or match them with clinical trials.
News • Depth-resolved fiber photometry
Tracking Alzheimer’s progression in real time
Scientists have developed a new method to track the build-up of amyloid plaques – a key characteristic of Alzheimer’s disease – in real time – an important step forward towards new treatments.
Article • Personalizing stroke care
Advancing genomic medicine from promise to practice with digital technology
Stroke patients in four NHS hospitals are now receiving genetic tests that determine whether a commonly prescribed drug will work for them – a breakthrough that could transform treatment for millions. Digital approaches are spearheading a drive to help make genomic medicine part of everyday care. The role of digital tools was a central theme at the HETT (Healthcare Excellence Through…
News • Peripheral immune tolerance
Immune system researchers receive Nobel Prize 2025 in Medicine
The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.
News • AML targetable immune escape mechanism
How leukemia cells trick the immune system
Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.
News • Research
Stuttgart researchers enhance CRISPR for cellular analysis
University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.
News • Virology
HIV genome integration mechanism decoded by German researchers
German researchers discover how HIV selects genome integration targets using RNA:DNA hybrids as guides, revealing new therapeutic approaches for controlling viral reservoirs.
News • Prediction of treatment sensitivity
Personalising prostate cancer treatment through molecular testing
A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.
News • Bacterial buildup to myocardial infarction
Heart attacks may be triggered by infection, study finds
An unexpected trigger for heart attack: Researchers show that dormant bacteria can contribute to atherosclerotic plaques and fatal myocardial infarction, effectively making it an infectious disease.
Article • On the hunt for skilled personnel
Staff shortage in the medical lab: solutions for a growing challenge
Shortages of skilled staff is creating challenges in medical laboratories across Europe. Many workers are nearing retirement age with numerous hospital laboratories having unfilled positions and facing the further issue of sharp competition from the pharmaceutical industry for skilled personnel. The challenges, and potential solutions, for medical laboratories were aired at a session looking…
News • Genomics
Chronic cough: study points to neurological mechanisms
Chronic cough affects approximately 1 in 10 adults in the UK, but the causes are often unknown and treatment options limited. Now, a new study has identified neurological mechanisms as key drivers.
News • Lifetime risk thresholds for mastectomy
Breast cancer: When should clinicians offer surgical options?
When should preventive mastectomy be offered for women at higher risk of breast cancer? A new evaluation model defines thresholds at which risk reducing surgery should be recommended.
News • Tracking current and emerging threats
Combined wastewater and individual testing for better virus detection
When someone is infected with a virus, traces of it are shed in their bodily waste and end up in the sewage system. Thus, combined wastewater and individual testing can benefit public health response.
News • Potential diagnostic medium
Saliva analysis could reveal risk of cancer, heart disease or Parkinson’s
Molecular markers in saliva could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases, new research finds.
News • Chromatin remodeling
New protein targets for cancer treatments
A research team at the University of Geneva has identified two new proteins that regulate gene expression, a discovery that could pave the way for new cancer and brain disorder treatments.
News • Genetic signature mapping
Diagnosing Parkinson’s from a blood sample
In a world first, researchers have identified a set of biomarkers that could someday make it easy to spot Parkinson's disease in a patient’s blood sample.
News • Machine learning analysis
Cancer genomics: new ML tool weeds out false positives
A major challenge in cancer genomics is separating meaningful mutations from false positives. A new tool uses machine learning to significantly reduce these errors.
News • Promising protein analysis tool
New blood test to enable rapid diagnosis of rare genetic diseases
An Australian research team has developed a blood-based method of analysing thousands of proteins in a single, untargeted test. This potentially enables rapid diagnosis of many rare genetic diseases.
News • Intestinal disease diagnosis
Next-generation tools find infections missed by standard tests
A University of Liverpool study has used advanced genetic and genomic techniques to offer a major step forward in understanding and diagnosing infectious intestinal diseases.
News • Amyotrophic lateral sclerosis
New insights on ALS onset opens paths to earlier treatment
New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.
News • New insights on CLEC5A
Immune gene discovery could prevent memory loss in Alzheimer's patients
A gene once believed to fight only viral infections could also hold the key to preventing memory loss in Alzheimer’s patients, a new study finds. This paves the way for new drug developments.
News • Cardiovascular research
Thousands of ‘digital twins’ offer new insights into the heart
Creating cardiac ‘digital twins’ at a large scale, researchers hope to gather new insights into heart health. This includes effects of age, sex, and lifestyle factors on heart disease risk.
News • Long-term risk assessment
MRI to identify cardiovascular disease ten years in advance
People at risk of cardiovascular disease could be identified a decade before they have a heart attack or stroke, a new University of Dundee study has discovered.
Article • San Antonio Breast Cancer Symposium (SABCS)
Young women and breast cancer: research in focus
At the San Antonio Breast Cancer Symposium (SABCS), three experts presented new approaches and study results for the treatment of breast cancer in young women.
News • Exploring the role of colibactin
Research links bacterial toxin to colorectal cancer
The incidence of colorectal cancer in young adults has doubled over the last 20 years, with no known reason. Now, a new study links this mysterious trend to childhood exposure to a bacterial toxin.
Anastasia Khvorova, PhD
Pioneering work in the field of RNA-based therapies for Huntington's disease
RNA researcher Anastasia Khvorova, PhD, professor of RNA therapeutics at UMass Chan Medical School, will receive this year's Else Kröner Fresenius Prize for Medical Research on May 15, 2025. The award ceremony will be a part of the festive event together with the Fresenius SE & Co. KGaA celebrating the 100th birthday of Else Kröner, at the Städel Museum in Frankfurt am Main.
News • Swedish national initiative
Precision omics to boost data-driven medicine
The new national Precision Omics Initiative Sweden (PROMISE) aims to generate and integrate extensive molecular data to create a model for precision medicine implementation for Sweden.
News • Targeting early versions
A 'head start' in the race against pancreatic cancer
Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.
News • Duchenne muscular dystrophy
Impact of DMD on the brain may be reversible, study finds
New research has revealed how Duchenne muscular dystrophy (DMD) also profoundly affects the brain, leading to cognitive and behavioural challenges that are very diverse and some could be reversible.
News • Machine learning analysis
Breast cancer: AI predicts metastasis from recurrence
The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.
News • Actionable genetic variants
Look into "Viking Genes" shows benefits of personalised health insights
A research project investigating the genetics and health of volunteers from the Hebrides, Shetland or Orkney shows how distinct genetic populations can benefit from tailored screening programmes.
Article • Promising, but in need of further validation
Implementation challenges of blood biomarkers for Alzheimer’s disease
Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…
News • Aldosterone-producing adenomas
The surprising complexity of adrenal gland tumors
New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.
News • Amyotrophic lateral sclerosis research
AML: sleep problems identified as early warning sign
Promising insights into amyotrophic lateral sclerosis (ALS): New research links characteristic symptoms of the disease, such as motor impairment and respiratory issues, to sleep disorders.
News • Alternative to diagnostic brain imaging
Exploring the potential of blood tests for dementia diagnosis
Molecular changes associated with brain inflammation and dementia can be detected in the blood. Researchers want to use this to establish blood tests as an alternative to more costly brain scans.
News • Multi-omics-based prediction
Pancreatic cancer: 'biomarker panel' brings hope for early detection
The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.
News • Age-related cellular and molecular changes
How aging breast tissue shapes breast cancer risk
Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.
News • Recent detections cause concern
Polio return to Europe: call for urgent action
Europe has been polio-free since 2002 – but a recent surge in poliovirus detections across several European countries shows that the threat from this vastly-forgotten disease is over, warn experts.
News • Osteosarcoma research
Driver behind aggressive bone cancer identified
By analysing the largest collection of whole-genome data from osteosarcoma patients, researchers identified a driving mechanism behind the aggressive development of these bone cancer tumours.
News • Potential for neurodegeneration
Head injuries may activate dormant viruses, trigger neurodegeneration, study finds
More than just a sports injury: A new study shows that head trauma may activate latent viruses, leading to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease.
News • Driving mechanism identified
Why the lung is a frequent site of cancer metastasis
More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the lungs such a tempting place for cancer cells? New research may have an answer.
News • Cancer development research
Exploring the role of sex in tumor growth
Tumors in female fruit flies grow significantly larger than in male ones, a new study finds. The findings could lead to a better understanding of how the biological sex impacts cancer development.
News • Advances in precision medicine
MASLD: Research reveals two types of fatty liver disease
Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.
News • Inhibition of Sars-CoV-2 proliferation
New 'hairpin' tool stops coronavirus in its tracks
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
News • Tumour movement across tissues
Understanding metastasis: migration strategies of ovarian cancer
A new study shows how inherent variations in a cancer cell and its interactions with its surroundings mould its migration. The findings provide valuable insights into the processes behind metastasis.
News • New insights on aneuploid epithelial cells
Breast cancer-like cells also found in healthy women
A certain type of cells, called aneuploid epithelial cells, are usually associated with breast cancer. However, new research reveals that they can also be found in healthy women.
News • Study on ventricular shapes
How heart shape links to cardiovascular disease risk
Researchers have published findings that show the genetic structure of the heart’s shape may offer new insights into individual heart health.
News • Incidentaloma detection
Liquid biopsy as diagnostic tool for pancreatic lesions
New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.
Article • Between good practice and financial pitfalls
Delivering molecular pathology at lower costs
Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.
News • Tradefair programme overview
Don't miss: Hot issues, current trends and innovations at the Medica 2024 Labmed Forum
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
News • Catch some EVs
Liquid biopsy to improve cancer diagnosis
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
News • Insights into bile production
Liver discovery could lead to better CVD treatments
A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.
News • From silent to destructive
Exploring the two phases of Alzheimer's disease
Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.
Sponsored • Innovation in action
Taipei showcases cutting-edge medical devices & diagnostics at Medica 2024
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
News • Irritable bowel syndrome
How genes determine the effectiveness of diets in irritable bowel syndrome
A European research team has now shown that dietary measures are more effective in IBS patients with defects in carbohydrate digestion genes than in those without these changes.
News • Hibernation
Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold
A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.
News • Microbiome research
Intensive research of intestinal microbiome: The vital role of small RNA in colonization
The gut microbiome varies from person to person in terms of the bacterial species represented and their colonization density. Segatella copri is the most prominent germ. Researchers at the Helmholtz Centre for Infection Research goal to clarify its health significance.
News • DNA damage response
New insights into the DNA damage response
The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.
News • Gene Therapy
Innovative gene therapy for hemophilia
Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.
News • Brain cancer immunotherapy
Turning immune cells against glioblastomas
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
News • Hard to treat cancers
KRAS “degrader” could lead to treatment for millions of cancer patients
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
News • Checkpoint inhibitor research
Five key factors predict response to cancer immunotherapy
Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.
News • MCMV based approach
Covid-19: vector vaccine offers long-term protection
Protection from established Covid-19 vaccines wanes relatively quickly. A new vector vaccine elicits prolonged immune response in animal models, and maintains its efficacy over extended time.
News • Automated tissue analysis
Digital pathology: AI platform to improve lung cancer diagnosis
Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.
News • Neurometabolism
Huntington: New insights into disease progression
Researchers discovered a gene that might be a key factor in the progression of Huntington’s disease in organoids. The gene may contribute to brain abnormalities much earlier than previously thought.
News • Antibiotic resistance control
Better tracking of AMR hospital bacteria
Infections caused by antibiotic-resistant (AMR) bacteria are a major issue in hospitals. A new technique aims to effectively track all types of relevant microorganisms simultaneously.
News • Focus on ILC immune cells
Research reveals cause for lupus kidney damage
Systemic lupus erythematodes can lead to severe kidney damage. However, until now, the cause for this remained unclear. New research has now revealed the underlying mechanism.
News • Duchenne muscular dystrophy
DMD: New tool helps manage neurobehavioral difficulties
Many patients with Duchenne muscular dystrophy (DMD) suffer from neurobehavioral difficulties that can significantly impact quality of life. A new screening tool shows promise for assessing this.
News • Patient-written symptom descriptions
ChatGPT struggles when medical questions are put in layman's terms
Enter symptoms into ChatGPT, receive an accurate diagnosis? Research reveals that LLM AI models are not quite there yet, struggling to identify genetic conditions from patient-written descriptions.
News • Cardiovascular magnetic resonance
Non-invasive MRI technique to predict heart failure risk
New resesarch suggests a new way of assessing the risk of heart failure without invasive diagnostic tests. The method involves MRI to measure heart pressure as a predictive factor.
News • Genome and transcriptome analysis
Colorectal cancer prognosis derived from genetic signatures
Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.
News • Promising diagnostic tool
Alzheimer's: New test to detect side effect risk from drugs
A novel test aims to predict whether Alzheimer’s patients are genetically predisposed to side effects from anti-amyloid drugs, a promising new class of Alzheimer’s therapeutics.
News • Promising study results
Cancer of Unknown Primary: on the way to targeted therapies
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
News • Concerns about hurried adoption
Survey: Is medical AI taking over too quickly?
The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.
News • Public survey on medical conditions
Cancer seen as #1 health concern, AI as solution
Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.
News • Taxane-induced peripheral neuropathy
New tool predicts nerve damage after breast cancer chemotherapy
Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.
News • Circulating tumor extracellular vesicles
Metastatic prostate cancer: better monitoring with new liquid biopsy method
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
News • Adaptive mutability
How bowel cancer flips the switch to avoid immune detection
Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.
News • Aortic analysis
Exploring the aorta's "weak spots" for aneurysms
Why do aortic aneurysms form where they typically do, at the upper arch or in the abdominal cavity? A new study explores the predilection of these sites for vascular dilatations.
News • Research on physical conditions
Exploring the link between obesity and cancer risk
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
News • Tracking the spread and evolution of superbugs
Mapping the movement of people (and their pathogen travel companions)
Integrating bacterial genomic data with detailed human mobility data makes it possible to see how pathogens causing pneumonia and meningitis, move between regions and evolve over time.
News • Disturbed lipid metabolism
Charcot-Marie-Tooth: Researchers uncover impact of genetic cause
Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.
News • Leukemia MRD after chemo
AML: Residual cancer testing as an important safeguard
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
News • Opportunity for new treatment approaches
Atherosclerosis and cancer share surprising similarities, study finds
In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.
News • Gene-snipping bacterial defenses
CRISPR: a promising tool to fight antibiotic resistance, but...
Could the 'gene scissors' CRISPR be used to make resistant bacteria susceptible to first-line antibiotics again? According to new reseach, yes – but the experts also point out serious caveats.
News • Ciliopathy reseach
Rare lung disease: genetics reveals cause of PCD
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
News • BRCA1 and BRCA2 malfunctions
Targeting 'exhausted' immune cells to prevent breast cancer
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
Article • Photon-counting CT, strain imaging, 4D flow MRI
How new technologies shape the future of cardiovascular radiology
New approaches to cardiovascular radiology are evolving to help clinicians gain an increasingly better insight into heart conditions. Latest developments in cardiovascular radiology include myocardial strain imaging, 4D flow and photon-counting CT technology. An ECR 2024 session shone the spotlight on these areas of cardiovascular imaging with expert speakers outlining the pros and cons of each.
Article • Interdisciplinary diagnostics
Crossing the radiology-pathology boundary
In diagnostics, there used to be a hard divide between radiology and pathology, where methods were largely considered incompatible with one another. However, to pave the way for next-generation diagnosis, Professor Regina Beets-Tan urged both sides to come out from their trenches and appreciate the synergies the fields have to offer. In her presentation at the European Congress of Radiology (ECR)…
News • Characterization of cancer relevant genes
Breast cancer: Researchers take a deep dive into cell lines
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
News • Noninvasive stratification
Multiplex PET helps doctors 'see' bowel cancer
Multiplex PET imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, according to scientists in Glasgow.
News • Neurodegeneration
New insights on cause of brain calcification
Much like joints or blood vessels, the brain can be affected by calcifications. This can lead to neurodegenerative disease, but is not well studied. Now, researchers from Norway identified a gene that provides new insights.
Article • Joint action
A pan-European effort to tackle cancer and NCDs
This February, the Norwegian Institute of Public Health officially launched the ‘Joint Action on cancer and other non-communicable disease prevention project‘ (JA PreventNCD). In the four-year-initiative, 22 EU member states plus Iceland, Norway and Ukraine have joined forces to combat the increasing burden of non-communicable diseases (NCDs) across national borders.
News • Women's health imaging
Breast cancer: MRI surveillance reduces mortality in BRCA1 high-risk women
An international study has revealed that MRI monitoring in women with mutations in the BRCA1 genes significantly reduces breast cancer mortality without the need for preventive mastectomy.
News • Revealed by AI
Prostate cancer: more than just one disease
Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer which could revolutionise how the disease is diagnosed and treated in the future.
News • Persistence of K. pneumoniae and E. coli
Exploring long-time colonization with resistant enterobacteria
Once a patient’s body has been colonized by resistant bacteria, they can persist for a long time, a new study by the University and University Hospital of Basel shows.
News • Blood-based diagnosis of glioblastoma
Sparing brain cancer patients from undergoing risky surgery
A simple blood test could help diagnose patients with glioblastoma, the deadliest form of brain cancer, sparing them from undergoing invasive and highly-risky surgery, report UK researchers.
News • Updated diagnostic criteria
Parkinson's: New three-type classification
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
Article • UK research project
"Our Future Health": Shifting from curative to preventive care
As a result from better living standards and medical advances, population longevity increases – a development which, paradoxically, current healthcare systems are ill-prepared for, Sir John Bell points out. The UK’s Our Future Health programme, which he chairs, exemplifies the paradigm shift to a prevention-centered healthcare approach.
News • Mammacarcinoma research
Study pinpoints breast cancer ‘cells-of-origin’ in high-risk women
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
News • Promising study in mice
Exploring the potential of mRNA technology for rare diseases
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
News • Finding therapy-relevant genetics
Leukaemia: AI provides support in diagnostics
Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.
News • Point-of-care diagnostic platform
Inhalable sensors for early lung cancer detection
Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.
News • Noninvasive fetal screening
Blood test to identify genetic diseases in unborn babies
A research team from Denmark has developed an innovative screening test. With a blood sample from the expectant mother, they can scrutinize all the genes in the fetus.
News • Expert prediction of financial aspects
Why precision medicine will save lives (but not costs)
While genetic information may lead to better treatments, promises of cost savings are unfounded. Instead, a large additional bill is more likely, according to University of Copenhagen researchers.
News • "Gene scissors" vs. sickle cell disease
FDA approves first CRISPR/Cas therapy
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
Article • Knowledge gaps in gender medicine
Covid-19 and sex: higher mortality of male patients
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
News • Ventricular fibrillation research
Promising therapeutic target for cardiac arrhythmias discovered
A newly discovered signaling mechanism implicated in the development of ventricular fibrillation offers promise of future treatment options for this life threatening condition.
Article • Infection control
The strain typing technologies of tomorrow
Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.
News • PDAC subtype classification
Attacking the roots of pancreatic cancer
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
News • Viral impostors
Pseudoviruses with click chemistry help understand infections
Würzburg resarchers have created a new pseudovirus design that allows tracking of penetration of viruses into cells.
News • Good killer cells
Cellular immunotherapy: a new approach against cancer
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
News • Common liver cancer in children
Potential targets to treat hepatoblastoma identified
A collaborative study, led by Cima Universidad de Navarra, has identified key epigenetic targets for the treatment of hepatoblastoma, the most frequent liver cancer in childhood.
News • New insights into genetic markers
Pregnancy can be a 'miracle cure' for rheumatoid arthritis – but why?
When a woman becomes pregnant, sometimes her pre-existing rheumatoid arthritis will 'magically' go away. In others, the condition becomes even worse. Now, US researchers may have found an explanation.
News • New imaging agent
HER2-positive breast cancer: Whole-body PET/CT predicts targeted therapy response
A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.
News • Preparing for the next pandemic
New rapid electronic diagnostic test for infectious diseases
A new molecular test for bacteria and viruses, including Sars-CoV-2, has been developed at the University of Surrey, as they warn that the world needs to be prepared for the next pandemic.
News • BRCA mutation vs family history
Breast cancer: Genetic test may make women misjudge their risk
A genetic test for BRCA1 or BRCA2 gene mutations may drive women to undergo breast cancer surgery, even though their risk might not even be drastically affected by this, a new study finds.
News • MEDICA Labmed Forum
Hot issues, current trends and innovations in lab medicine
From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.
News • Surge in under 50s in past decades
The rising tide of early-onset cancers
Cancer has become strikingly more common in people under 50 in the past three decades, an international research team finds. The reseachers explore what this means for future death tolls.
News • Biomarker-based predictions
AI drives precision oncology for colorectal cancer
For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).
News • Tool for myeloid neoplasms
New test to identify risk of AML and related cancers
Using data from more than 400,000 individuals, researchers have created a platform for predicting the risk of developing blood cancers such as acute myeloid leukaemia over a 10-15-year period.
News • Presented at AACC 2023
AI to predict multiple sclerosis, detect contaminated lab samples
The 2023 AACC meeting saw two exciting AI applications in lab medicine: a predictive algorithm for MS, and machine learning for detecting contaminated lab samples.
News • Advanced biosensor
Researchers engineer tumor-detecting bacteria
Scientists from the University of California San Diego and their colleagues in Australia have engineered bacteria that can detect the presence of tumor DNA in a live organism.
News • Promising application of "gene scissors"
Using CRISPR-Cas9 to treat anaemia
ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia: beta thalassaemia and sickle cell anaemia.
News • Proof-of-concept research
Researchers reverse chemotherapy-related fertility loss
A new study by investigators from Brigham and Women’s Hospital demonstrates the potential for restoring fertility when the ovaries have stopped working.
News • Hypertrophic cardiomyopathy imaging
Combining cDTI and CMR to detect deadly heart condition
Combining two types of heart scan techniques could help doctors to detect deadly hypertrophic cardiomyopathy (HCM) before symptoms and signs on conventional tests appear.
News • Genotype-specific strategy
‘Digital twins’ of patients’ hearts give insights into cardiac health
Scientists have developed a tool to create a digital replica of an individual's heart, which could inform the diagnosis and treatment of cardiovascular diseases.
News • Real-time tumor profiling
AI tool decodes brain cancer’s genome during surgery
Scientists have designed an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery — critical information that can guide treatment decisions.
News • Multi-ancestry polygenic score
Dataset diversity improves heart disease risk prediction
By using genetic data on multiple traits from people of non-European ancestry, scientists have improved the accuracy of polygenic scores in predicting disease risk for all.
News • From 529 million to 1.3 billion cases by 2050
Diabetes: Experts predict drastic increase in the next 30 years
More than half a billion people are living with diabetes worldwide, and that number is projected to more than double to 1.3 billion people in the next 30 years.
News • Counteracting neuroinflammation
Multiple sclerosis: Why women get better when pregnant
Women suffering from multiple sclerosis temporarily get much better when pregnant. Researchers have now identified the beneficial changes naturally occurring during pregnancy.
News • Beyond polygenic risk scores
Adding blood biomarkers to genomics to better predict common disease risk
New research suggests that combining blood biomarkers with genomic information more accurately, cost-effectively predicts the risk of developing diseases.
News • Chronic myeloid leukaemia
CML therapy response predicted by AI "crystal ball"
AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.
News • Prostate cancer detection
Personalized PSA screening may improve accuracy
The accuracy of prostate-specific antigen (PSA) screening can be improved by including genetic factors that cause changes in PSA levels not associated with cancer, according to a multi-center study.
News • Potential for new treatments
Researchers find new subtypes for ovarian cancer
New research from the University of Helsinki increases the understanding of ovarian cancer: the identification of new subtypes could help discover new treatments.
News • HSNCC treatment stratification
Head and neck cancer: using organoids for personalized therapy
Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).
News • Bias in datasets
Diversity is a challenge for rare disease-detecting AI, study finds
Most AI techniques for rare disease diagnosis use anthropometric measurements of European origins, ignoring the genetic and morphological diversity of humans, a new study finds.
News • Research on mini organs
Organoids bring new insights into liver cancer
Dutch scientists have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer.
News • Oncology & Biomedical Technology
New treatment option in bone cancer: gene therapy combined with chemotherapy
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
News • Genetics & Viruses
"Gene scissors" in human cells inhibit viral infections
Scientists at the University of Applied Sciences Krems (IMC Krems) show that CRISPR-Cas9 can also be used to inhibit viruses such as adenoviruses in cell cultures.
News • Breast cancer
Study shows: Association between antibiotics and an increased risk of death after breast cancer
Women with triple-negative breast cancer who received multiple antibiotic prescriptions within three years after their cancer diagnosis were more likely to experience disease recurrence and to die from their cancer.
News • Neuroscience & Alzheimer's disease
Researchers identifiy subset of neurons that are most susceptible to Alzheimer's disease
Neurodegeneration, or the gradual loss of neuron function, is one of the key features of Alzheimer's disease. However, it doesn't affect all parts of the brain equally.
News • Genetics & Neuroscience
Research investigates the convergence of schizophrenia risk genes in brain coexpression networks
Johns Hopkins researchers, along with colleagues in Italy, have published a study that looks into the genetic mechanisms behind the development of schizophrenia.
News • Oncology & Immunology
Research shows promising results for better treatments of aggressive brain cancer
For decades, researchers have marveled at the ability of glioblastoma, a particularly aggressive brain cancer, to turn off a patient's cancer-fighting immune cells, thereby allowing tumors to grow freely.
News • Genetics & Neuroscience
Improvement of stroke diagnosis and treatment through specific genes
Genes are full of clues about a person's health and might also show the way for stroke recovery.
News • Oncology & health informatics
Colon cancer: AI tool predicts survival, treatment response
A new artificial intelligence model could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer.
News • HIV & hepatitis detection
HIV, hepatitis B and hepatitis C can be detected from a single drop of blood, study shows
Data on a test that can detect HIV, hepatitis B and hepatitis C from a single drop of blood is being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases.
News • Genetic diseases
Study sheds light on causes of rare genetic diseases in 5,500 people
Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study in the U.K..
News • Prevention of blood cancer
Research identifies new target that may prevent blood cancer
An international coalition of biomedical researchers has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.
News • Electric stimulation instead of drug therapy
A new approach to treat Charcot-Marie-Tooth (CMT) Disease
A research team from DGIST develops an electronic medicine technology that restores abnormal protein behavior, the cause of Charcot-Marie-Tooth Disease (CMT).
News • Hypertension and the brain
Study links high blood pressure to memory loss and dementia
A new study led by the University of Edinburgh has identfied areas of the brain susceptible to damage from high blood pressure, affecting memory loss, thinking skills and dementia.
News • Blood cancer research
Novel disease models for multiple myeloma
A team of scientists has successfully generated genetically defined mouse models for two subtypes of multiple myeloma. This will contribute to a better understanding of how the disease develops in humans.
News • Up to 12 year in advance
Urine gene test can predict bladder cancer years before diagnosis
Testing for genetic mutations in urine can detect bladder cancer years before the disease shows clinical symptoms, new research has shown - reaching more than a decade for the most common cancer type.
News • Overlooked by most doctors
Income and ethnicity identified as risk factors for cardiovascular disease
According to Dutch researchers, people with low income are up to 1.5 times more at risk of a heart attack or stroke than their wealthier compatriots. Ethnicity was also identified as a risk factor.
News • Novel therapeutic strategy
Chemogenetics for the treatment of challenging epilepsy cases
Scientists from Japan demonstrated, for the first time, a successful chemogenetic suppression of widespread epileptic seizures in macaque monkeys. Their findings represent an essential step towards clinical trials, and effective treatment for patients with severe epilepsy.
News • Tissue meets tech
Researchers grow electrodes in the brain
Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body’s molecules as triggers.
News • SARS-CoV-2 genetic material in wastewater
Using sewage to forecast Covid-19 infections
A new mathematical model developed by Hokkaido University engineers uses wastewater samples to effectively forecast the number of clinical Covid-19 cases in a community five days in advance.
Article • Radioembolization
Breast cancer metastasis: benefits and limitations of trans-arterial therapy
Evidence that radioembolization, a trans-arterial therapy, is safe and stops disease progression in metastatic breast cancer is increasing, a prominent American interventional radiologist showed at the Spectrum conference in Miami.
News • Researchers improve DNA cut-and-paste technique
Increasing safety for "gene scissors" CRISPR-Cas9
A new approach on the genetic tool CRISPR-Cas9 could reduce the risk of unwanted mutation, making it safer for use in humans, Dutch researchers have found.
News • Dissection, rupture, dilatation
Aortic stability assessment to identify high-risk patients
MRI-derived wall shear stress values predict pathological changes in the aortic wall in patients with ascending aortic dilatation. This can help identfy at-risk patients.
Video • Mini-bones from the lab
Toward a personalized approach of bone cancer research and therapy
Researchers generated human mini bones in the lab which mirror the composition and function of human bone - a step toward the development of future patient-tailored models of bone cancers and tumors.
News • Medication and surgery recommendations
Childhood obesity guidelines: the end of 'watchful waiting'
The American Academy of Pediatrics has issued its first comprehensive guideline on the evaluation and treatment of children and adolescents with obesity, marking an end to previous recommendations.
News • Intestinal distress
Multiple sclerosis: a closer look at the gut microbiome
Findings of bacteria with anti-inflammatory effects in the intestines of MS patients with no evidence of active disease indicate that diet, bacteria and disease progression are linked.
News • Hereditary non-polyposis colorectal cancer
Lynch syndrome: AI improves colorectal cancer screening
Researchers have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.
News • Patient-derived whole-tumor cell culture model
Breast cancer: New method finds the right therapy
Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.
News • Potential and pitfalls of CRISPR
Gene therapies raise difficult legal and ethical questions
New advanced therapies can alleviate or cure chronic diseases. But medical progress, such as the gene editing tool CRISPR, raises the question of how rights should be protected and balanced.
News • Promising reseach results
Using artificial DNA to kill cancer
Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way. The method showed promising results against various cancers in lab tests on mice.
Article • Image augmentation, interpretation and evaluation
AI in multimodality hybrid imaging: a diamond in the rough
AI-based models for multimodality hybrid imaging have the potential to be a potent clinical tool but are currently held back by a lack of transparency and maturity, says Dr Irène Buvat, from the Laboratory of translational Imaging in Oncology, Institute Curie in Paris, France.
News • Novel approach in pathology
Laser microbiopsy: a minimally invasive method to extract tissue samples
In a recent study, a US research team developed a revolutionary laser-based approach to perform microbiopsies. Their novel method could make biopsies faster, more cost-effective, and less harmful to the patient.
News • Drivers of health disparities
The impact of racism and discrimination on global health
Racism, xenophobia, and discrimination are important influences on health globally, but have so far been overlooked by health researchers, policymakers, and practitioners, finds new research.
News • MCED test
Groundbreaking new method for multi-cancer early detection
An international study shows that a new method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods.
News • Precision medicine
Localising BRCA gene mutations to better treat ovarian cancer
An international team highlights the importance of localising BRCA1 and BRCA2 gene mutations for the treatment of ovarian cancer.
News • Increased infection risk
AMR: drug resistant bacteria can travel from gut to lung
A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.
Article • Don't miss:
Talks and panel discussion at the Labmed forum
At this year's Medica tradefair, laboratory medicine, medical technology and life sciences give new impulses to the entire healthcare market - especially in times of the corona pandemic. An overview.
News • Metastatic recurrence
Researchers discover mechanism responsible for colon cancer relapse
Researchers in Barcelona discovered the population of residual tumour cells responsible for the recurrence of colorectal cancer in other organs after removal of the primary tumour.
News • Tumor location as important growth factor
New molecular microscopy uncovers breast cancer spread
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease.
News • CLL types with distinct biological and clinical features
Whole genome profiling reveals new leukaemia subgroups
A collaborative study has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukaemia (CLL), and associated these with clinical outcomes.
Article • Brain imaging
White matter hyperintensities: a valuable biomarker to assess mortality risk
White matter hyperintensities (WMH) on the brain seen on MRI represent a biomarker associated with a 50/50 risk of death within five years after a first incident acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Article • Detecting several different diseases
Multiplex diagnostics: next-generation techniques for new challenges
With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.
Sponsored • Diagnostics Alliance against SARS-CoV-2
The Global Alliance for Diagnostics Sets Next-Generation POC Molecular Testing Collaboration
The coronavirus pandemic is a huge challenge for global public health and welfare. Decentralized, affordable POC MDx platforms would allow more effective control of SARS-CoV-2 and other infections.
News • New treatment approach
Colon cancer: Overcoming chemotherapy resistance
Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.
News • Leukemia research
How 'chameleon cancers' change their colors to survive treatment
Some leukemias evade treatment by changing their appearance and identity through changing the read-out of their DNA, a new study has found.
News • CSCC study finds distinct subgroups
Cervical cancer: major new clue to understanding aggressiveness
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
News • Children’s cancer
Rhabdomyosarcoma: Blood tests could offer smarter treatment
A simple 'liquid biopsy' blood test could help guide the treatment of children with the cancer rhabdomyosarcoma, a new study reports.
News • Answer to SARS-CoV-2 mutations
One step closer to 'variant-proof' Covid-19 vaccine
A vaccine design approach that could protect against new variants of SARS-CoV-2 but also potentially protects against other coronaviruses is one step closer to reality as a result of new research.
News • Researchers develop noninvasive approach
FUSIN: Delivering gene therapy with ultrasound
Treatment of central nervous system diseases and tumors is often hindered by the blood-brain barrier. A new method aims to overcome this obstacle using focused ultrasound intranasal delivery (FUSIN).
News • Infection control
Legionnaire's disease: genetic analysis key to understanding risk
Routine sampling of water supplies and genomic sequencing of Legionella bacteria could play a key role in identifying the source of Legionnaires’ disease outbreaks, research suggests.
News • How cancer spreads
Cancer metastasis: Breakthrough to lead to better treatments
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
News • Cancer research
Key function of important leukemia gene demystified
The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team now showed that EVI1's cancer causing effect relies on activating a single gene — the stem cell transcription factor ERG.
News • Hopeful study
A noninvasive way to diagnose endometriosis
Women can suffer for years with the debilitating pain and medical complications of endometriosis without a diagnosis. Now, researchers believe they may be able to diagnose the condition using just menstrual blood.
News • Conference attendance
New lab systems for virology showcased at ESCV 2022
Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.
News • Streptococcus pneumoniae
Technique helps discover whether bacteria are antibiotic resistant
A new study could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae, which cause meningitis, are resistant to antibiotics.
Article • Infection prevention
Vaccination: why ‘positive consensus’ is crucial
Vaccination projects across the world are at a pivotal post-Covid moment, according to one of the leading experts in the field. Speaking to Healthcare in Europe ahead of the World Innovation Summit for Health (WISH) congress in Qatar – where vaccination will be a central topic – Dr Jerome Kim said there is an urgent need to regain a ‘positive consensus’ around the value of vaccines. He…
Article • Modelling systems for human biology
Organoid technology: new opportunities for drug discovery
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
News • High-glade glioma research
Understanding why deadly brain cancer comes back
A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.
News • Tumor identification in CUP patients
Cancer of unknown primary: comprehensive molecular analysis can improve therapy
A considerable proportion of patients suffering from cancer of unknown primary (CUP) could benefit from comprehensive molecular analysis and molecularly-informed targeted therapies.
Article • Preventing clinical errors
Supporting transgender health in the clinical laboratory
Clinical laboratories need to be proactive to attract transgender patients for testing and to ensure that they are comfortable with the services provided. This issue is of great importance to the American Association for Clinical Chemistry (AACC), which conducted a scientific session on transgender health at its recent annual meeting in Chicago.
Video • Clonal somatic mutations
How does cancer grow? Genetic mapping gives new insight
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
News • Spit take
Portable diagnostic detects SARS-CoV-2 RNA and antibodies
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
News • Cardiomyopathy research
Genetic defects can cause heart failure
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
Article • Outbreak prevention and management efforts
Infectious diseases: new challenges for EU monitoring
Avian flu, MERS, Covid-19, monkeypox: outbreaks of infectious diseases are getting more common in Europe. As a result, the EU must adapt its surveillance strategies and introduce more data-driven, interdisciplinary countermeasues.
News • Gene therapy in the heart muscle
Targeting heart disease with viral vectors
Researchers have developed adeno-associated virus variants that target heart muscle cells and can thus be used for the precise treatment of heart diseases.
News • Cell production changes as an early warning
Blood test could predict future risk of leukaemia
A blood test could predict risk of developing leukaemia in the elderly population years in advance by identifying changes in blood cell production, according to new research.
News • Betacoronavirus protection
Nanoparticle vaccine protects against Covid-19 variants and related viruses
A new type of vaccine provides protection against a variety of SARS-like betacoronaviruses, including SARS-CoV-2 variants, in mice and monkeys, according to a new study.
News • Novel disease therapies
"Soft” CRISPR may offer fix for genetic defects
A new approach makes use of natural DNA repair machinery and provides a foundation for novel gene therapy strategies with the potential to cure a large spectrum of genetic diseases.
News • Not just for bitcoin
Blockchain can secure and store genomes
Blockchain is a digital technology that allows a secure and decentralized record of transactions. Now, researchers leveraged blockchain to give individuals control of their own genomes.
News • Eye treatment
Self-plugging microneedle for drug delivery
Reseachers have developed a novel microneedle for injecting therapeutics into the eyes, potentially solving one of the major challenges of treating eye diseases.
News • AI approach to colorectal tumors
Deep learning identifies molecular patterns of cancer
A new AI platform can analyze genomic data extremely quickly, picking out key patterns to classify different types of colorectal tumors and improve the drug discovery process.
News • Genetics research
Chromosomes: How the 'extra X factor' is putting men at risk
Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis.
News • Faulty gene is catalyst
New liver and kidney disease identified
Scientists have identified a new disease in a ground-breaking discovery that could help patients with unexplained liver and kidney problems.
Article • Glioblastoma analysis
Revealing tell-tale signs of deadly brain cancer
A new way of differentiating healthy from diseased cells could pave the way for more personalised treatment for patients diagnosed with glioblastoma multiforme (GBM), a common and aggressive type of brain tumour.
News • Hypoxia
Stopping lung damage before it turns deadly
Scientists at the La Jolla Institute for Immunology discover new drug target for severe asthma and fibrosis.
News • Elusive variants
Rare genetic markers of drug-resistant tuberculosis identified
The search for rare mutations in bacterial genome could lead to better diagnostics and treatments – reducing morbidity caused by the deadly disease.
News • Cancer therapy side-effects
Researchers investigate link between chemotherapy and infertility
In order to better prevent and restore fertility and reduce the risk of sterility in cancer survivors, researchers investigate the mechanisms behind negative effects of chemotherapy.
News • Metabolic disorders
Decoding a direct dialog between gut microbiota and brain
Hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and body temperature accordingly.
News • Regenerative medicine
Injectable stem cell assembly for cartilage regeneration
Researchers have established an injectable hybrid inorganic nanoscaffold-templated stem cell assembly and applied it to the regeneration of critically-sized cartilage defects.
