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News • Fluorescence assay
A 'FAIRY' to rapidly determine virus infectivity
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
New research reveals a promising approach to developing a universal influenza vaccine that confers lifetime immunity against an evolving virus considered most likely to trigger the next pandemic.
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
When point-of-care testing (POCT) models for diagnosing infectious disease are effective, the quality of pathology results can be equivalent to laboratory tests, new research shows.
Burnout, fear of infection, lack of support: One in three doctors and nurses considered leaving their job, or the healthcare profession altogether, during the Covid-19 pandemic, a new study shows.
A new approach to vaccine development could produce vaccines before the disease-causing pathogen – such as a new variant of the coronavirus Sars-CoV-2 – even emerges.
New research provides cause for optimism that long Covid can resolve over time. Following people from the first wave of Covid-19, it monitored the longevity of immune abnormalities after an infection.
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
A recent suggestion to stop using the term ‘long-Covid’ may have been well-intentioned, but could ultimately do more harm than good, experts point out.
Using ultrasound imaging to detect Covid-19 infections, a new automated detection tool could help doctors in the emergency room diagnose patients quickly and accurately.
Patients who are suffering from aftereffects of a coronavirus infection often receive the diagnosis 'long Covid'. However, new research presented at ECCMID 2024 calls that term into question.
New study results explore the long-term effects of infection with Sars-CoV-2, and challenge the idea that vaccine immunity fades quickly.
How does a coronavirus infection cause neurological symptoms such as headaches, memory problems, and fatigue? A new study points to a different reason than previously assumed.
A new way to analyze blood samples for suspected sepsis gives doctors test results two days earlier than before – a head start that could mean life or death for patients.
During the Covid-19 pandemic, Switzerland relied on contact tracing to identify people likely to have been contaminated by an acquaintance. A research team assessed the effectiveness of this method.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
Researchers from the University of Southampton investigated how ultraviolet laser light destroys the coronavirus Sars-CoV-2 by impacting components critical for infection.
A new, large-scale study from Sweden underlines the importance of vaccination against Covid-19: The research shows that an infection raises the risk of heart rhythm disturbances.
Using diffusion MRI technology, researchers in Sweden have found differences in brain tissue structure between patients with persisting symptoms after Covid-19 and healthy people.
Being overweight – not just being obese – can increase Covid-19 severity. the elevated BMI creates an impaired antibody response to SARS-CoV-2 infection but not to vaccination, new research finds.
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
A new study on public health communication shows that the term commonly used to describe bacteria resistant to current medicines or antibiotics fails to stick in people’s memories.
Researchers from Osaka University present a novel technique to detect different coronavirus variants quickly, including fast-spreading strains present in human saliva.
What does the future of the coronavirus look like? An international research team from Cologne and New York has developed a model to predict the likely evolution of Sars-CoV-2.
A new study found that the antibody response of infants and young children against Sars-CoV-2 deviates from that of adults in a small, but very significant way.
New research from Copenhagen University Hospital – Rigshospitalet and Herlev and Gentofte Hospital has shed new light on the immune system’s complex struggle against the coronavirus.
The enhanced infection safety measures installed for the Covid-19 pandemic also had a beneficial effect on hospital-acquired infections (HAIs) overall, a new US study suggests.
For their contributions to developing mRNA vaccines to fight Covid-19, Katalin Karikó, PhD, and Drew Weissman, MD, PhD, have been jointly awarded the 2023 Nobel Prize in Physiology or Medicine.
A new molecular test for bacteria and viruses, including Sars-CoV-2, has been developed at the University of Surrey, as they warn that the world needs to be prepared for the next pandemic.
Researchers from Rutgers University developed a way to help hospitals identify life-threatening Covid-19 cases using machine-learning software. The algorithm identified six crucial parameters.
A research team led by the Institute for Bioengineering of Catalonia (IBEC) and Hospital del Mar has conducted a study to analyze cough sounds recorded by smartphones in patients with Covid-19.
Two new studies based on a large-scale cohort in Denmark explored the side effects of the coronavirus vaccine – one focused on acute effects, the other on a women's health issue.
Patients with immunodeficiency cannot benefit from conventional Covid-19 vaccines and still at risk from infection. A promising new approach now brings hope for this patient group.
Researchers from the University of Chicago developed a deep-learning model to assess chest X-ray radiographs for probable Covid-19 severity.
Researchers in France identified changes to the immune memory after infection with the Omicron BA.1 variant in thrice-vaccinated patients. The remodeling actually works to the patients' benefit.
A family physician at Tufts University School of Medicine offers advice for how to treat allergies and how to tell if symptoms are due to allergies, the common cold, the flu, or Covid-19.
A new device that combines microfluidics on paper, electrochemical transduction and immunoassays on magnetic nanoparticles is useful for easy and rapid diagnosis of lung diseases.
Combining aerosol sampling and ultrasensitive biosensing, researchers have created a real-time monitor that can detect any of the Sars-CoV-2 virus variants in a room in about 5 minutes.
Do coronavirus vaccines skew the menstrual cycle, cause more bleeding or pain? Anecdotal reports hint at a connection. Now, a new study led by Boston University provides answers.
Research by the University of Southampton has shown that repeated Covid-19 vaccination increases the ability of lymphoma patients to prevent infection from the virus, particularly after four doses.
A new publication discusses deep-ultraviolet (DUV) photonics for the disinfection of Sars-CoV-2 and its variants (Delta and Omicron) in the cryogenic environment.
An MRI invention from engineers at the University of Waterloo reveals better than many existing imaging technologies how Covid-19 can change the human brain.
Gentle cleansers are just as effective in killing viruses – including coronavirus – as harsh soaps, according to a new study from scientists at the University of Sheffield.
A study led by the National Institutes of Health’s RECOVER Initiative and supported by NYU Langone Health provides an expanded working definition of long Covid.
German researchers have now investigated whether there is a temporal association between infection with the Sars-CoV-2 virus and the development of type 1 diabetes.
Protection offered by Covid-19 vaccination declines more rapidly in people with severe obesity than in those with normal weight, scientists at the Universities of Cambridge and Edinburgh have found.
A study by investigators from the Mongan Institute at Massachusetts General Hospital shows serious effects in many aspects of the lives of health care workers due to the pandemic.
Getting vaccines to people who need them isn't always easy. Many vaccines require cold storage, making it difficult to ship them to remote areas that don't have the necessary infrastructure.
Messenger Ribonucleic Acid (mRNA) as a therapeutic approach is gaining momentum due to its ability to be rapidly manufactured and its promising outcomes.
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.
Among all but oldest age groups, the US has higher death rates than five high-income European nations, according to new UCLA research. However, this gap is only partly due to Covid-19.
US scientists report using a single-atom-thick nanomaterial to simultaneously detect Covid-19 and flu viruses — at much lower levels and much more quickly than conventional tests for either.
Predicting a Covid-19 infection from the sound of a cough? Researchers found that technology using Machine Learning performed no better than simply asking people to report their symptoms.
Researchers at the Universitat Autònoma de Barcelona (UAB) have developed a new type of nanoparticles inspired by the structure of amyloids, capable of neutralising the SARS-CoV-2 virus.
True or false: Webcams have only recently been introduced in neonatology and are a patient-side component of the Digital Health Portfolio. False! Already in 1989, Professor Dr Roland Wauer at Charité Berlin built his DIY system to transmit images from the neonatology ward.
A new mathematical model developed by Hokkaido University engineers uses wastewater samples to effectively forecast the number of clinical Covid-19 cases in a community five days in advance.
Researchers have developed an inhalable powder that could protect lungs and airways from invasion from the coronavirus or flu viruses by reinforcing the body’s own mucosal layer.
Nurses who worked in critical care during the Covid pandemic are at an increased risk of mental health problems, according to a new study.
The European Football Championship in 2021 had an impact on the participating countries' coronavirus infections, a new study shows. However, the extent depended greatly on the initial situation.
A novel imaging agent can reduce the number of false-positive PET/CT findings among cancer patients recently vaccinated for Covid-19. This may mitigate the issue of tracer uptake in lymph nodes associaed with the vaccine.
After an infection with SARS-CoV-2, some people fail to recover their sense of smell. US researchers took a closer look at the olfactory nerve cells to find the reason for Covid-19-induced anosmia.
A newly developed rapid test needs only a few seconds to reliably detect pathogens such as SARS-CoV-2. It is based on specially designed magnetic nanoparticles.
A new study has found that antibodies produced in the nose decline nine months after Covid-19 infection, while antibodies found in the blood last at least a year.
Covid-19 vaccinations that combine two or more distinct variants of SARS-CoV-2 could offer protection against current and future ‘variants of concern’, say scientists from UK and Austria.
A new study demonstrates that AI models, using symptom and demographic features, can help predict Covid-19 infections, providing a way for rapid screening and cost-effective infection detection.
How does the coronavirus actually work? Dutch researchers have produced an animated video to visualise the life cycle of the virus using real-life microscopic images of infected cells.
In their pursuit of solutions for pandemic challenges, a US hospital system applied telemedicine principles to respiratory therapy – with impressive results.
Researchers tracked viruses passing through face masks and compared their failure on the filter layers of different mask types. This could accelerate the development of surfaces that can kill viruses.
A promising new application for photon-counting CT: The new technology outperforms conventional CT in detecting subtle damage in the lungs of patients with persistent symptoms of Covid-19.
Adults with asthma had, at one point, an approximately doubled risk of a severe asthma attack after Covid-19 restrictions were relaxed in the UK, according to new research.
Eunsin Bae, M.D. specializes in laboratory medicine and leads the Institute of Clinical Research at Seegene Inc. Her research focuses on microbiology, molecular biology, and hematology. Dr. Bae is currently working toward implementing a global clinical study and establishing an international network of clinical investigations.
Innovative gastrointestinal imaging, medical panel PCs with hygiene optimisation, smartphone-based diagnostic tools, and sustainable hardware setups: At Medica 2022, manufacturers from Taiwan again showed their capability to adapt and provide solutions for a world radically changed by the Covid-19 pandemic. Under the “Taiwan Excellence” banner, outstanding products from the island nation’s…
Using a special type of MRI, researchers have uncovered brain changes in patients up to six months after they recovered from Covid-19, according to a study being presented at the annual RSNA meeting.
During the Covid-19 pandemic, the use of these single-use diagnostics, or point-of-care tests has exploded. This is having major environmental consequences, experts point out.
There is no evidence of higher risk of miscarriage or ectopic pregnancy following vaccination against Covid-19 or infection with the disease, according to a new study.
Innovative smart weighing scales are adding a new dimension to home monitoring for healthcare. By collecting data via sensors and proprietary technology as people stand on them, the scales can assess health metrics to give users more precise measurements for a deeper understanding of their body.
A new X-ray technology has been used to identify a link between the damage that severe Covid-19 can inflict on lungs and pulmonary fibrosis, a disease that causes severe scarring of lung tissue.
Until now, it was feared that vaccination against Covid-19 could reduce the success of treatment for patients with nasopharyngeal cancer. A recent study now gives the all-clear in this regard.
Speed or accuracy? As far as Covid-19 tests go, this was the choice you had to make. In the future, this dilemma could be a thing of the past.
Donor hearts from people who were Covid-19-positive appear to be as safe for transplantation as those from people without Covid-19, according to a new short-term analysis.
The Pluslife Mini Dock System is a Next-Generation POC molecular diagnostic tool that can be used in different application scenarios, which aims to help the decentralization of MDx in diagnosing facilities.
Despite treatment, chronic lung diseases such as COPD or cystic fibrosis can become so severe that a lung transplant is necessary. Dr Urte Sommerwerck explains which patients might be considered for transplantation and why follow-up is as important as the surgery itself.
The coronavirus pandemic caused by SARS-CoV-2 and its variants is still a major public safety issue worldwide. The “alpha” variant B.1.1.7, the “gamma” variant P.1, the “beta” variant B.1.351, and the “delta” variant B.1.617 are of particular concern because of their high prevalence. Large-scale vaccination and sensitive detection are vital for preventing the spread of Covid-19.
The coronavirus pandemic is a huge challenge for global public health and welfare. Decentralized, affordable POC MDx platforms would allow more effective control of SARS-CoV-2 and other infections.
Research presented in a new preprint suggests that SARS-CoV-2 might have been artificially created in a laboratory. Experts from Würzburg have reviewed the paper – and remain unconvinced.
A vaccine design approach that could protect against new variants of SARS-CoV-2 but also potentially protects against other coronaviruses is one step closer to reality as a result of new research.
A new study finds that virtual care during the Covid-19 pandemic led to a significant reduction in CO2 emissions and patient travel-related expenses, such as gasoline, parking or public transit costs.
Covid-19 has led to global mortality changes unprecedented in the last 70 years, according to new research. However, the drop in life expectancy is not equally high in all countries.
A study in Japan finds antibody response to the Moderna Covid-19 mRNA vaccine does not vary depending on the time of day when the dose was received.
Referrals to Cambridge’s long Covid clinic fell dramatically in the period August 2021 to June 2022, which researchers say is likely due to the successful rollout of the vaccine.
Researchers have shown that when brain cells are directly exposed to blood taken from Covid-19 patients with delirium, there is an increase in cell death and a decrease in the generation of new brain cells.
It’s widely known that more than 70% of today’s medical decisions involve the results of laboratory tests, but the insights clinicians derive from these tests today may only be scratching the surface of their potential.
A research group has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.
What will the next pandemic look like? Health officials from across the globe gathered in Geneva in late August at a World Health Organization meeting to focus on how lessons learned from Covid-19 might best prepare civilization for the "next one."
How can rapid antigen tests be adjusted to reliably detect future variants of SARS-CoV-2? A research team funded by the National Institutes of Health is currently working on finding an answer.
An international team of researchers advises that strong care needs to be taken not to misuse or overuse machine learning (ML) in healthcare research, despite all of its benefits.
A new system capable of reading lips with remarkable accuracy even when speakers are wearing face masks could help create a new generation of hearing aids.
Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.
Artificial intelligence (AI) can be used to detect COVID-19 infection in people’s voices by means of a mobile phone app, according to research to be presented at the European Respiratory Society International Congress.
Vaccination projects across the world are at a pivotal post-Covid moment, according to one of the leading experts in the field. Speaking to Healthcare in Europe ahead of the World Innovation Summit for Health (WISH) congress in Qatar – where vaccination will be a central topic – Dr Jerome Kim said there is an urgent need to regain a ‘positive consensus’ around the value of vaccines. He…
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
Danish smokers bought less tobacco and more quit smoking during the Covid pandemic, new research finds. This comes as a surprise given that mental health and exercise habits waned during the lockdown.
The overall risk of myocarditis is substantially higher immediately after being infected with Covid-19 than it is in the weeks following vaccination for the coronavirus, a large new study shows.
New diagnoses of disorders including psychosis, dementia, seizures and ‘brain fog’ remain commoner two years after Covid-19 than after other respiratory infections, new research finds.
The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.
At the ECR 2022 congress in Vienna, Hologic went beyond just showcasing new systems for women’s health. Additional focus topics were the mitigation of the pandemic impact on screening programmes and the situation of women around the world without access to advanced diagnostic technologies – or even the most basic standards of healthcare.
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
More than 225,000 tweets with the hashtags #scamdemic and #plandemic led to an “infodemic” of misinformation and disinformation on Twitter during the first year of the pandemic, a new study finds.
Avian flu, MERS, Covid-19, monkeypox: outbreaks of infectious diseases are getting more common in Europe. As a result, the EU must adapt its surveillance strategies and introduce more data-driven, interdisciplinary countermeasues.
Researchers propose a new Covid-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies - a promising alternative for people with a weakened immune system.
Long Covid sufferers have experienced a wider set of symptoms than previously thought including hair loss and sexual dysfunction, new research has found.
As knowledge about Covid-19 advances, so does the arsenal of techniques to predict, diagnose and follow up on the disease. At ECR, researchers presented a range of promising imaging modalities to keep track of Covid-19 symptoms, severity, and mortality, often including AI support to enhance or accelerate diagnostics.
Researchers have developed a new Covid-19 test distribution method that uses drones to quickly deliver at-home diagnostic tests to individuals who suspect they have Covid-19.
A sprayable coating that can prevent the surface spread of infection from bacteria and viruses – including Covid-19 – over a sustained period has been developed by Australian researchers.
Leading radiologists have debated whether working from home is a blessing or a curse amid the evolving impact of teleradiology. In a hybrid ECR session examining working from home in radiology, speakers discussed their own experiences.
Skin swabs are "surprisingly effective" at identifying Covid-19 infection, according to new research, offering a route to a non-invasive future for Covid-19 testing.
The Covid-19 pandemic has highlighted the importance of the fast and accurate diagnosis of infectious diseases in clinical settings. Harald Maier discusses the implementation of rapid molecular diagnostics in the central clinical diagnostics laboratory at Innklinikum Altötting and Mühldorf, highlighting how the use of PCR testing has benefitted the hospital during the Covid-19 pandemic.
Researchers have been able to produce antibodies to the SARS-CoV-2 spike protein in hen eggs. Antibodies harvested from eggs might be used to treat Covid-19 or as a preventative measure.
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from Geneva reveals the exceptional capacity of Omicron to evade our immunity.
A new type of vaccine provides protection against a variety of SARS-like betacoronaviruses, including SARS-CoV-2 variants, in mice and monkeys, according to a new study.
Using functional MRI with inhaled xenon gas, researchers have identified that long COVID symptoms are related to microscopic abnormalities that affect how oxygen is exchanged from the lungs to the red blood cells.
Staff across all levels of UK health and social care reported feeling betrayed, morally violated and being treated unjustly and unfairly at work during the Covid-19 pandemic.
Russia's war against Ukraine is also playing out in cyberspace. In the process, clinics in Germany could also be caught in the digital crossfire, IT experts warn.
Recovery from severe Covid-19 is characterized by a reduction of certain white blood cells and changes in the molecular regulation of the immune system, an international research team found.
Handheld, instrument-free test delivers lab-quality molecular results – 97.9% accuracy – in about 15 minutes, right at the point of care.
Over the past years, the world has been transforming into a post-Covid era. Taiwan has stepped up to the challenge on innovation and taking the advancement of digital healthcare to a whole new level.
A research group from Kyoto developed two in vitro models to study SARS-CoV-2, and showed that they can be used for drug screening for infectious diseases including Covid-19.
COVID-19 pandemic has caused “global collateral damage” by disrupting cardiac services . Across the world problems with heart health will “...continue to accrue unless mitigation strategies are speedily implemented”.
When a virus makes its way into the body, one of the immune system’s first responders is a set of pathogen-removal cells called macrophages. But they don’t all target viruses in the same way.
A special type of MRI found lung abnormalities in patients who had previously had COVID-19, even those who had not been hospitalized with the illness.
Researchers have developed a novel way to fabricate diagnostic devices using paper-based microfluidics that can be rapidly prototyped and scaled for manufacturing.
In patients with serious and long-term Covid-19, disturbed blood coagulation is often observed. Now, Swedish researchers found a connection between harmful amyloid production and Covid-19 symptoms.
SARS-CoV-2 depends on the broadly antiviral interferon-induced human transmembrane proteins , to enter human cells and replicate inside them.
Two years after infection with COVID-19, half of patients who were admitted to hospitals still have at least one symptom, according to the longest follow-up study to date.
UV radiation is one of the go-to methods for preventing the spread of SARS-CoV-2. But what UV dosage kills the virus? What wavelength? How long? A new study answers many of those questions.
In 2020 and 2021, the death toll associated with Covid-19 was approximately 14.9 million, according to the World Health Organization. However, the global distribution has been far from equal.
Personalised screening, data-driven aproaches: In a dedicated press conference in Paris, French oncologists presented promising research that might bring hope for many cancer patients.
Cognitive impairment as a result of severe Covid-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, scientists found.
A method for delivering genetic material to the body that has proven useful in Covid-19 vaccination is now being tested as a way to repair damaged heart muscle after a heart attack.
Six in ten people with Covid-19 still have at least one symptom a year later, a new study has found. Furthermore, symptoms that don’t clear up after 15 weeks are likely to last at least a year.
Using mass spectrometry and chromatography techniques, UK researchers have developed an approach to predict infection severity among Covid-19 patients, as well as potential outcomes.
A global analysis of nearly 6 million Covid-19 deaths finds an increase in mortality at weekends compared to weekdays. Bureaucratic and reporting delays alone do not explain this, researchers report.
By comparing the infectious viral load caused by ancestral SARS-CoV-2 as well as by the Delta and Omicron variants, scientists highlight the benefits of vaccination.
A new study enables developers to determine vaccine safety via smart sensors that measure objective physiological parameters. This could end the reliance on subjective reports of study participants.
The COVID-19 testing device can detect coronavirus infection in as little as 30 seconds as sensitively and accurately as a PCR test.
Point-of-care testing (POCT) is a “win-win” scenario for patients and healthcare professionals in delivering care when and where it is needed, according to pathologist Adil Khan, MSc, PhD.
Hygienic, single-use components are widely used in endoscopy to ensure patient safety but are considered wasteful. Reprocessing is a more sustainable alternative but requires special equipment and training to avoid equipment contamination. This creates an area of conflict for physicians, hospital staff, but also for manufacturers. We spoke with two experts at Pentax Medical about challenges in…
SARS-CoV-2 has heavily impacted global society with high pressure on public health and economics. MolGen is proud to assist in relieving some of the pressure and support the testing framework.
Contrast agents in the wastewater and power-hungry imaging systems: The eco-footprint of healthcare is huge, and radiology departments are among the main culprits. An expert panel at the ECR Overture explored ways to make the field “greener”.
Researchers have found another long-term complication associated with Covid-19 infections: peripheral neuropathy during and following their bouts with the virus.
To provide a solution for the challenges of the coronavirus pandemic, Beckman Coulter recently launched the DxU Iris, a urinalysis solution which aims to improve lab workflows.
A significant number of Covid-19 neurological complications – such as fatigue, headache, and cognitive impairment – are ultimately reversible, according to new research.
People who were bedridden for at least a week due to Covid-19 are more likely to experience anxiety and depression for up to 16 months after the infection, a new study shows.
The MD-Bio BCC19 Coronavirus test utilizes RT-LAMP technology to provide accurate results in just 30 minutes.
The new 3D-printable mask design promises easy breathing for users while maintaining similar levels of protection against pathogens found in N95 and surgical masks.
Combining questions about a person's health with data from smartwatch sensors, a new app can predict within minutes whether someone is infected with COVID-19.
COVID-19 measures such as school closures and ‘high-traffic and mixing’ areas had the strongest association, providing clues for new intervention approaches.
A new study has analyzed over 3000 proteins to identify which are causally linked to the development of severe Covid-19. This provides insight into potential new targets for treatment and prevention.
Traces of the SARS-CoV-2 coronavirus that causes COVID-19 can be detected in microscopically small fluid droplets exhaled during a very short time span.
The tool has made it possible to detect SARS-CoV-2 in exudate from symptomatic patients with a sensitivity of 100% and a specificity of 87.5%
The Covid pandemic might be responsible for a “substantial decrease” in mental wellbeing in the UK, according to new research from the University of East Anglia and University of York.
A new UK review shows that people who have had one or more doses of a coronavirus vaccine are less likely to develop long Covid than those who remain unvaccinated.
Is the Underground a safe means of transport in times of Covid-19? A computer simulation, developed at the University of Leeds, has calculated the infection risk.
Scientists have confirmed that an inhaled form of COVID vaccine can provide broad, long-lasting protection against the original strain of SARS-CoV-2 and variants of concern.
Researchers have developed an inexpensive, non-toxic coating for almost any fabric that decreases the infectivity of the virus that causes COVID-19 by up to 90 per cent.
Researchers have developed a noninvasive and reagent-free technique for the efficient detection of COVID-19.
Professor Richard Neher from the Biozentrum of the University of Basel is using his Nextstrain platform to investigate which variants of the SARS-CoV-2 virus are currently circulating worldwide.
Researchers from Charité – Universitätsmedizin Berlin and Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) present new findings on the immune response against SARS-CoV-2.
A new study shows that the SARS-CoV-2 Omicron variant is less effective than Delta at blocking a cellular defence mechanism against viruses, the so-called 'interferon response'.
How long can Covid-19 antigen tests reliably tell the antibody status? Researchers at the Paul-Ehrlich-Institut identified several factors that affect the detection duration.
A passive air sampler clip can help assess personal exposure to SARS-CoV-2, which could be especially helpful for workers in high-risk settings.
Researchers have developed a diagnostic for SARS-CoV-2 that is capable of differentiating between COVID-19 and the garden-variety bug with fast turnaround.
The COVID-19 pandemic has led to deficiencies and large inequalities in the care of mothers and newborns in Europe.
The long-term impact of the coronavirus pandemic on antimicrobial resistance remains difficult to predict. Infectious diseases consultant Professor Alison Holmes reflects on Covid-19's effect on antibiotic use in hospitals and beyond.
Scientists at have designed a quantum sensor to detect SARS-CoV-2 faster, cheaper, and more accurate than the current gold-standard technique, PCR.
Ever since the Abbe diffraction limit of conventional microscopy has been surpassed, super-resolution techniques have been diving ever deeper into the most miniscule details of molecular structures. We spoke with Prof. Dominic Zerulla, whose company PEARlabs is developing an imaging technique that sets out to push the boundaries once more – by looking at in-vivo nano-scale processes in motion.
The Coronavirus SARS-CoV-2 infects the kidneys and contributes to tissue scarring, as shown by researchers from Germany and the Netherlands.
An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants.
Using a new x-ray imaging approach, an interdisciplinary research team has detected significant changes in the heart muscle tissue of people who died from Covid-19.
The Omicron variant of SARS-CoV-2 may be significantly better at evading vaccine-induced antibodies – but preliminary evidence suggests it is less likely to cause severe illness in the lungs.
An invisible protective wall of UV-C light developed by researchers in Munich could reliably curb the spread of viruses and other pathogens in rooms while allowing total freedom of movement.
A worldwide consortium aims to equip researchers in low- and middle-income countries (LMICs) with cheap and accessible methods for sequencing large collections of bacterial pathogens.
Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…
Researchers in the UK and China have developed an AI model that can diagnose Covid-19 as well as a panel of professional radiologists, while preserving the privacy of patient data.
Radiologists in Paris have developed a standardised simple visual lung damage CT severity score for Covid-19 patients who do not have symptoms of severe acute respiratory syndrome (SARS) at the time of initial treatment.
Doctors in Lisbon report on the case of a 61-year-old man who received a double lung transplant after his lungs were irreparably damaged by Covid-19.
When the coronavirus first struck in the US, hospitals in New York City were the first to feel the impact. Radiologists Professor Judy Yee, M.D., and Mark C. Liszewski, M.D., describe the lessons learned and talk about their firsthand experiences.
A large-scale qualitative study looks into the difficulties frontline doctors faced across two waves of the Covid-19 pandemic in the UK and Ireland since early 2020.
Safety trials are underway for a Cambridge-led vaccine that could be used as a booster targeting Covid-19 virus variants and relatives that threaten future coronavirus pandemics.
Founded in 2018 as a DNA extraction chemistry company, Dutch company MolGen entered the market operating within the agricultural sector. At first, the company’s founders, Maarten de Groot, Wim van Haeringen and Niels Kruize, focused solely on this one industry, mainly developing and marketing advanced bulk chemistry kits for DNA/RNA extraction. These testing products and solutions successfully…
A new strategy to reduce the spread of COVID-19 employs a mobile robot that detects people in crowds who are not observing social-distancing rules, navigates to them, and encourages them to move apart.
In experiments using saliva samples from COVID-19 patients, the gum, which contains the ACE2 protein, neutralized the virus.
Test could measure patient immunity against multiple COVID-19 variants such as Omicron and Delta at once and inform which synthetic monoclonal antibody to use for treatments.
After the four-day run, organisers of Medica and Compamed express their satisfaction with the results of the events in Düsseldorf. From 15 to 18 November 2021, the world’s leading information and communication platforms for the medical technology industry and its supplier sector presented a wealth of convincing innovations as well as an accompanying programme that covered a wide range of…
Compared to previous SARS and MERS, SARS-CoV-2 became a pandemic due to the high infectivity and different mode of contagion. SARS-CoV-2 spreads more because it is contagious also before symptoms, during incubation phase. No tests to date have been able to find the virus during the pre-symptomatic stage. Stark has developed a new, rapid, non-invasive method "Stark Portable Covid-19 Antigen…
Video streaming of surgeries, augmented reality displays and at-home assessment of sleep apnea: Medtech companies from Taiwan will showcase their newest products at Medica in Düsseldorf. Ahead of the trade fair, the Taiwan External Trade Development Council (TAITRA) presented award-winning examples of the nation’s ingenuity.
The Corona pandemic has a major impact on all areas of life. Nearly everyone is affected in some way – in their health, in their jobs, in their entire lives. But there are also notable bright spots. Chief among these effects is the rapid development of vaccines, test kits and, in the future, medicines that are making a significant contribution to overcoming the crisis. Microfluidic components…
The damage caused by Covid-19 to the lungs’ smallest blood vessels has been intricately captured using high-energy X-rays emitted by a special type of particle accelerator. Scientists used a new imaging technology called Hierarchical Phase-Contrast Tomography (HiP-CT), to scan donated human organs, including lungs from a Covid-19 donor.
There has been a "positive shift" in inclusive gender practices in Covid-19 vaccine research, but there is still room for improvement, experts say. Women have been equally recruited and represented in randomised control trial research about Covid-19 vaccine safety, efficacy and effectiveness, according to a new study by The George Institute for Global Health and The Australian National…
A study by the Universities of Basel and Saarland shows that there is almost no risk of transmission of the Covid-19 virus on the field. They suggest that blanket quarantine measures for opposing teams are not justified if no close contact has taken place off the playing field. Governments have introduced various measures over the past 18 months in an effort to curb transmission of the Covid-19…
French researchers have found that addressing concerns related to the Covid-19 vaccination via a chatbot interface might be capable of swaying the vaccine-hesitant. Vaccine hesitancy is one of the major challenges in containing the Covid-19 pandemic. Previous studies have revealed that mass communication—through short messages relayed by television or radio—is not a very effective means of…
“Twindemic” is a term that has not yet been in the headlines but is likely to become part of our lexicon as the summer progresses.
Scientists at Lausanne University Hospital (CHUV) and École polytechnique fédérale de Lausanne (EPFL) have discovered a highly potent monoclonal antibody that targets the SARS-CoV-2 spike protein and is effective at neutralizing all variants of concern identified to date, including the delta variant. Their findings are published in the journal Cell Reports.
A new rapid molecular diagnostic test from Cepheid has received the CE mark for distribution in the European market. The test, called Xpert Xpress CoV-2/Flu/RSV plus, is designed for qualitative detection of the viruses causing Covid-19, Flu A, Flu B, and respiratory syncytial virus (RSV) infections from a single patient sample. The new plus version of the test provides a third gene target for…
The Covid-19 crisis that gripped England between September 2020 and June 2021 can be thought of as a series of overlapping epidemics, rather than a single event, say researchers at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and the German Cancer Research Center.
Making recommendations for change, academics analyzed global data into the prevalence of antimicrobial resistance in urban areas—the rise of which is threatening the lifesaving role of the medications.
Hope for a future without fear of Covid-19 comes down to circulating antibodies and memory B cells. Unlike circulating antibodies, which peak soon after vaccination or infection only to fade a few months later, memory B cells can stick around to prevent severe disease for decades. And they evolve over time, learning to produce successively more potent “memory antibodies” that are better at…
After infection with SARS-CoV-2, where does the immune system store the memory to provide long-term protection against reinfection? Though numerous studies have examined blood to track immune responses to SARS-CoV-2, a new study of Covid survivors shows that the memory of the infection is primarily stored in T and B cells within the lung and the lymph nodes surrounding the lung.
Water, hygiene and infection prevention solutions and services provider Ecolab launches its Hand Hygiene Compliance Measurement (HHCM) System, a digitally connected technology to systematically monitor and improve hand hygiene in healthcare settings, across Europe. In healthcare settings, clean hands save lives. While the Covid-19 outbreak increased adoption of hand hygiene measures at first,…
The impact of the coronavirus pandemic on lung cancer patient care across Europe, and the contribution lung pathologists, have led to a better understanding of Covid-19, as outlined during the 33rd European Congress of Pathology, Within ‘The lung pathologist in the Covid-19 pandemic’ session, speakers detailed how the pandemic has affected patients, diagnosis and clinical trials, yet also…
The number of colorectal cancer (CRC) cases diagnosed fell dramatically by 40% in a year during the Covid-19 pandemic, new research presented at United European Gastroenterology (UEG) Week Virtual 2021 has shown. The research, which was conducted across multiple hospitals in Spain, compared data from the first year of the Covid-19 pandemic with data from the previous year. Of 1,385 cases of CRC…
Medical technology startup EpiGuard has received the 2021 Oslo Innovation Award. Presented during the first day of the of Oslo Innovation Week, the Scandinavian city’s annual technology festival, Ellen Cathrine Andersen, CEO of EpiGuard, collected the award from Vegar Andersen, advisor for the City of Oslo’s Vice Mayor for Business Development and Public Ownership.
A study found that women who contract Covid-19 during pregnancy are at significantly higher risk of developing pre-eclampsia. In their study, researchers said their systematic review shows that women with SARS-CoV-2 infection during pregnancy had 62% higher odds of developing preeclampsia than those without the infection during pregnancy.
Long COVID symptoms rarely persisted beyond 12 weeks in children and adolescents unlike adults.
A treatment combining two antibodies is recommended for two specific groups of patients with Covid-19 by a WHO Guideline Development Group panel of international experts and patients.
Study suggests need for better ventilation and tight-fitting masks, in addition to widespread vaccination to help stop spread of the virus.
According to new research, vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death from 14 days post the second dose vaccination, when substantial immunity should be expected.
Thousands of unvaccinated French health workers face suspension without pay under a new COVID-19 law that punishes people in care professions who refuse to get immunised against the virus.
Hospitalized Covid-19 patients are substantially more likely to harbor autoantibodies — antibodies directed at their own tissues or at substances their immune cells secrete into the blood — than people without Covid-19, according to a new study.
Colourful, 3D rendered scientific images are fascinating - but can they deceive viewers? New research from Spain suggests this might be the case. According to the study by the Instituto de Radio Televisión Española and the Universitat Autònoma de Barcelona conducted during the Covid-19 lockdown, black and white images of SARS-CoV-2 make the virus seem more infectious. The results, published on…
To better prepare and protect the world from global disease threats, H.E. German Federal Chancellor Dr Angela Merkel and Dr Tedros Adhanom Ghebreyesus, World Health Organization (WHO) Director-General, have inaugurated the new WHO Hub for Pandemic and Epidemic Intelligence, based in Berlin.
Covid-19 infection does not appear to affect the lung function of young adults, according to new research presented at the ‘virtual’ European Respiratory Society International Congress. In the first study to investigate the impact of Covid-19 infection on lung function, researchers led by Dr Ida Mogensen, a post-doctoral fellow at the Karolinska Institute, Stockholm, Sweden, found that even…
Researchers in Thailand have developed a device to get the most out of vaccine supplies: The automated vaccine filling machine from the Faculty of Engineering at Chulalongkorn University can fill AstraZeneca vaccine into syringes with precision, speed, and safety, helping to increase the number of vaccinated people by 20 percent. The prototype is now operating at Chula Vaccination Center and more…
Adults who have received a double vaccination are 49% less likely to have Long Covid should they contract a Covid-19 infection, according to new research from King's College London. The scientists analysed data from participants logging their symptoms, tests and vaccines on the UK ZOE COVID Symptom Study app between 8th December 2020 and 4 July 2021, including 1,240,009 (first dose) and 971,504…
Delegates at an international radiography conference were given an insight into the impact Covid-19 has had on their profession and practice in five countries across the world. A special session at the online ISRRT (International Society of Radiographers and Radiological Technologists) congress in Dublin (August 20-22) heard experiences from Thailand, Nigeria, Italy, India and Ireland, with…
The World Health Organization (WHO) has taken a closer look at coronavirus variant B.1.621. The strain, first encountered in January 2021 in Colombia, shows traits that could enable the virus to circumvent immune response to vaccination. As a result, the variant, named "Mu", has been classified as "Variant of Interest" (VOI). Despite its prominence in Colombian new infection,…
Unsupervised deep learning breaks new ground by predicting the progression of COVID-19 and survival of patients directly from their chest CT images.
Researchers from the University of Oxford have announced the results of a study into thrombocytopenia (a condition with low platelet counts) and thromboembolic events (blood clots) following vaccination for Covid-19, some of the same events which have led to restricted use of the Oxford-AstraZeneca vaccine in a number of countries.
Scientists have grown beating heart cells to attempt to identify drugs to prevent Covid-19-related heart damage. Concerns over the extent of cardiac damage among Covid patients emerged during the coronavirus pandemic and there are also suggestions that the impact on cardiomyocytes could contribute to the symptoms of long Covid. To explore these issues, a research team at the University of…
Each wave of the pandemic has underscored just how contagious Covid-19 is, but there is less clarity among experts on exactly when—and to what extent—infected individuals are most likely to spread the virus.
Obtaining two vaccine doses remains the most effective way to ensure protection against the Covid-19 Delta variant of concern dominant in the UK today, according to a study from the University of Oxford. Conducted in partnership with the Office of National Statistics (ONS) and the Department for Health and Social Care (DHSC), the study found that with Delta, Pfizer-BioNTech and Oxford-AstraZeneca…
New research from the University of Oxford and the UK Centre for Ecology & Hydrology uses mathematical modelling to determine the most equitable way to share vaccines between nations. Vaccines provide a route to achieving high levels of immunity against SARS-CoV-2 across populations, and provide a route to reopening economies, tourism, and livelihoods. However, vaccine resources amongst…
A new study of patients with cerebral venous thrombosis (CVT) following Covid-19 vaccination provides a clearer guide for clinicians trying to diagnose and treat patients. The research, led by University College London (UCL) and UCL Health and published in The Lancet, is the most detailed account of the characteristics of CVT, when it is caused by the novel condition vaccine-induced immune…
Covid-19 disease severity is determined by the individual patient’s immune response. The precise mechanisms taking place inside the lungs and blood during the early phase of the disease, however, remain unclear. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität Berlin have now studied the cellular mechanisms…
Researchers identify two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants. The team, spearheaded by researchers at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – may have found the “Achilles’ heel” of the virus, with potential for pan-variant therapeutic interventions. The findings are now published in the EMBO…
Some people change the narrative about technology and society. One of them is Nuria Oliver, Chief Data Scientist at Data-Pop Alliance, Chief Scientific Advisor at the Vodafone Institute, and Co-founder and Vice-president of the European Laboratory for Learning and Intelligent Systems (ELLIS). In an interview with HiE, she explains how she develops computational tools and uses artificial…
A research team led by scientists in the labs of Jennifer Doudna, David Savage and Patrick Hsu at the University of California, Berkeley, is aiming to develop a rapid Covid-19 diagnostic test that is much faster and easier to deploy than qRT-PCR. It has now combined two different types of CRISPR enzymes to create an assay that can detect small amounts of viral RNA in less than an hour. Doudna…
Microwave engineers, infectious disease specialists and polymer scientists from the University of Edinburgh, Heriot-Watt University and the University of Strathclyde have teamed up to create a novel microwave sterilisation method that could revolutionise the way ambulances and hospitals are being disinfected.
Italy, France, and Greece have made Covid-19 vaccination mandatory for healthcare workers, and England is making it compulsory for care home workers and consulting on whether to extend this to healthcare workers and other social care staff. Experts debate in The BMJ whether frontline health and social care workers should be compelled to take up the vaccine, if efforts to encourage them fail.…
Israel’s first virtual hospital has been created following the advances and applications learned from using telemedicine tools and techniques to care for coronavirus patients in isolation wards. Sheba Beyond was established in January and over the last few months has successfully delivered care to patients across a range of areas. The development of the project was outlined to the DMEA –…
A novel study published in AACC’s The Journal of Applied Laboratory Medicine shows that delaying the second Covid-19 vaccine dose for more than the recommended 3-4 weeks results in higher antibody levels. This finding could play a vital role in shaping vaccine distribution strategies that increase access to the vaccine around the globe.
How long do coronaviruses remain infectious on banknotes and coins? Is it possible to become infected through contact with cash? Experts at the European Central Bank, in collaboration with the Department of Medical and Molecular Virology at Ruhr-Universität Bochum, wanted to clarify this question. The researchers led by Professor Eike Steinmann and Dr. Daniel Todt developed a method specifically…
Home test kits to check for Covid-19 spike proteins and anti-Covid-19 antibodies are fast and simple to use but lack the sensitivity and accuracy of laboratory tests. Researchers from Eindhoven University of Technology with Utrecht University have developed a new type of sensor that combines the sensitivity and accuracy of current laboratory-based measurements with the speed and low-cost of…
In view of the continuing high numbers of infections, vaccination offers important protection against severe Covid-19 disease. Scientists from the Faculty of Medicine – University of Freiburg have now been able to determine in detail at what time point initial immune protection is established after vaccination with an mRNA-based vaccine and how the reactions of the various components of the…
Patients who experience long Covid have reported more than 200 symptoms across 10 organ systems, in the largest international study of ‘long-haulers’ to date, led by scientists at University College London together with a patient-led research collaborative.
Markers in our blood – ‘fingerprints’ of infection – could help identify individuals who have been infected by SARS-CoV-2, the coronavirus that causes Covid-19, several months after infection even if the individual had only mild symptoms or showed no symptoms at all, say Cambridge researchers. The team has received funding from the National Institute for Health Research to develop a test…
David Johnson, Global Director Commercial Excellence at ADVANZ PHARMA, explains the value of off-patent medicines to hospitals and healthcare systems, as the repercussions of the Covid-19 pandemic are still having a significant impact on resources.
The Lausanne University Hospital (CHUV) and EPFL teamed up to develop a new test that’s sensitive enough to measure the amount of SARS-CoV-2 neutralizing antibodies present in the bloodstream. The scientists’ discovery, published in Science Translational Medicine, opens promising new avenues for tracking immunity acquired by infection or vaccination.