News • Insights on bias avoidance
New breast imaging technique to improve visibility across skin tones
A new imaging technique reduces skin tone bias in breast cancer detection, improving visibility across diverse skin tones.
Search for: "Cancer Research" - 250 articles found
News • New therapy approach for brain tumors
Attacking glioblastoma from multiple angles
A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.
News • Interstital lung disease
Lung cancer: PET/CT imaging analysis with AI predicts immunotherapy side effects
PET/CT image analysis using artificial intelligence (AI) can predict the occurrence of interstitial lung disease, a serious side effect of immunotherapy in lung cancer, a new study shows.
News • Incidentaloma detection
Liquid biopsy as diagnostic tool for pancreatic lesions
New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.
Article • Between good practice and financial pitfalls
Delivering molecular pathology at lower costs
Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.
News • Do no harm
“Never words” in doctor-patient communication (and what to say instead)
“There’s nothing else we can do”, “Why did you wait so long to come?” – doctors should avoid using such phrases. A new study points out the destructive potential of “never words”.
News • Tradefair programme overview
Don't miss: Hot issues, current trends and innovations at the Medica 2024 Labmed Forum
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
News • Research on new sensing mechanism
Finding signs of lung cancer in exhaled breath
Researchers from China have developed ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer.
Sponsored • GI Genius enters NAIAD large-scale clinical trial
AI making earlier detection of colorectal cancer possible
Early detection is crucial for effective treatment of colorectal cancer, but the initial stages are easily missed during endoscopy screenings. With GI Genius, Medtronic presents an AI-powered tool to help detect precancerous lesions in real-time. In an upcoming large-scale trial, the intelligent endoscopy module will demonstrate its benefit in the clinical context.
News • Microgravity-induced changes
How cancer cell cultures in space can help defeat cancer on Earth
New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.
News • Insights into tumor biology
Breast cancer: Exploring metastasis diversity
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
News • Research on "double strike" mechanism
Induction of defective cell division could improve blood cancer therapy
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.
News • Photothermal disinfection
Frying bacteria on implants with tiny gold radiators
New technology shows promise in protecting an implant against infections from resistant bacteria: By heating up small nanorods of gold with near-infrared light (NIR), the bacteria are killed.
News • Catch some EVs
Liquid biopsy to improve cancer diagnosis
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
News • Insights into bile production
Liver discovery could lead to better CVD treatments
A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.
News • Radiopharmaceutical study
New mini-protein shows promise in targeted radiation delivery to tumors
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
Sponsored • United Imaging debuts new PET/CT platform at EANM 2024
Celebrating molecular imaging milestones across Europe
United Imaging launches the uMI Panvivo, the uMI Panorama GS and Nuclear Medicine AI Solution at EANM, and announces strategic partnerships, reinforcing its commitment to advancing molecular imaging in Europe and beyond.
Video • Cancer research
3D-printed tumor model reveals metastasis mechanisms
New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.
Sponsored • Innovation in action
Taipei showcases cutting-edge medical devices & diagnostics at Medica 2024
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
Interview • Congress showcases advances
Making immunotherapy work for more cancer patients
Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.
News • PFAS and Kidney Health
New research reveals connection between PFAS, kidney function and gut health
New research has revealed that the connection between PFAS, and kidney damage may be tied to dysregulation of the gut microbiome.
News • Hibernation
Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold
A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.
News • Cancer treatment advances
USC study findings: early blood test forecasts survival rates in patients with metastatic prostate cancer
A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.
News • DNA damage response
New insights into the DNA damage response
The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.
Interview • AI, modern mammography, and more
Breast imaging breakthroughs presented at EUSOBI 2024
Minimally invasive surgical interventions, innovative imaging and the use of AI: At the upcoming EUSOBI congress in Lisbon, experts present and discuss the latest advances in breast imaging. We spoke with Tanja Brycker from Hologic ahead of the event about new trends in women’s health, the company’s investment in innovation and education, and what the future of mammography looks like with the…
News • Miniature instrument transport
Robotic "convoy" advances endoscopic surgery
Miniature robots often lack the strength to transport instruments for endoscopic microsurgery. But what if they worked together? Scientists have pursued this idea to perform a surgical procedure.
News • Discussion on nomenclature
“Prostate cancer” or “incidentaloma”: What should early findings be called?
Certain early-stage changes to the prostate very rarely develop into aggressive cancer, but are still called that. Would it create a false sense of security to not call these “cancer” at all?
News • BAC as predictor of cardiovascular disease
Mammograms can detect more than breast cancer, study finds
Measuring the calcium build up in the arteries of the breast, researchers have developed an AI-generated score for predicting cardiovascular disease in women from their mammograms.
News • Single-cell metabolic profiling
Mass-spec and IMC give deep insights into tumors
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
News • Brain cancer immunotherapy
Turning immune cells against glioblastomas
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
News • Experts propose combination strategy
Kidney cancer: early detection through 'piggyback' screening
Kidney cancer is relatively rare, so dedicated screening programmes would not be cost-effective. Combined with lung cancer screening, however, this would be much more feasible, a new study shows.
News • Hematology
Using AI to predict multiple myeloma evolution
Researchers have succeeded in identifying patterns of response to treatment in patients with multiple myeloma using AI tools, which helps to accurately predict the evolution of the tumor.
News • Hard to treat cancers
KRAS “degrader” could lead to treatment for millions of cancer patients
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
News • Transport of minuscule gold particles
Nanoparticles could detect kidney disease better than blood tests
Before administering certain drugs, doctors check a patient’s kidney function by testing their blood urea nitrogen and creatinine levels. New research shows that gold nanoparticles might give more accurate results.
News • Individualized therapy planning
Tumour irradiation: a little different every day
A bit more mucus in the nose, a little less air in the gut: Even small changes can be important when planning proton therapy against cancer. A new workflow allows for an adapted irradiation every day.
News • Groundwork for new treatments
Fibrosis a prognostic biomarker for HER2-negative breast cancer
A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.
News • Breast cancer detection
Decade of DBT: 10-year study shows benefits of tomosynthesis
Evidence of the superiority of tomosynthesis for breast cancer detection is stacking up, with new results from a 10-year study further demonstrating the 3D imaging technique's benefits.
News • Strengthening the immune defense
STAb-T: new immunotherapy method shows promise against lung cancer
STAb-T, a new form of immunotherapy to treat solid tumours shows therapeutic potential in animal models with non-small cell lung cancer. The new strategy is designed to strengthen the defensive cells.
News • AnWj blood group antigen
MAL: new blood group system discovered
Researchers identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of patients lacking this blood group.
News • When red means bad (for the heart)
Nutri-Score hints at foods that increase CVD risk
The Nutri-Score is designed to provide consumers with information on nutritional quality. New research reveals that the ratings also correspond with the cardiovascular health impact of the products.
News • Checkpoint inhibitor research
Five key factors predict response to cancer immunotherapy
Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.
News • Multimodal analysis
Immunotherapy: tumour microenvironment holds clues to treatment success
Currently, it is difficult to predict whether a cancer patient will respond to immunotherapy or not. A new method to quantify the heterogeneity of the tumour microenvironment aims to improve this.
News • Research on BRCA recurrence
Breastfeeding after breast cancer treatment is safe, studies find
Two international studies presented at the ESMO Congress 2024 show no increase in recurrence or new breast cancers in women who breastfeed after being treated for breast cancer.
News • Glioblastoma research
Brain scars from cancer treatment key factor for relapse
Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.
News • Dynamic network analysis
AI unlocks new path to personalized cancer treatments
A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.
News • Reducing chemotherapy side effects
Trapping cancer cells in molecular 'cages'
Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.
News • COPD and asthma
Certain lung conditions could "mask" lung cancer, delay diagnosis
Certain long-term health conditions such as chronic obstructive pulmonary disease (COPD) and asthma, can obscure early symptoms of lung cancer, leading to delays in diagnosis, a new study finds.
News • Quicker, cheaper and less painful test
Blood crystals to reveal early signs of prostate cancer
A new method of analysing the crystals in dehydrated blood could lead to a quicker, cheaper and less painful technique to diagnose, early detect, and monitor prostate cancer.
News • Breast cancer screening
The emotional impact of false positive mammograms
Mammography can lead to “false positives,” meaning they do not result in a breast cancer diagnosis. This may discourage some women from future screenings, according to a new study.
News • Towards personalised risk assessment
Training an AI to early detect dementia with big data
With enough medical training data, AI can predict health conditions with astounding accuracy. Now, researchers want to use brain scans of the entire Scottish population to have an algorithm early detect dementia.
News • High-resolution cell scans
AI spots cancer and viral infections at nanoscale precision
Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.
News • Remote procedure from Hongkong to Zurich
Telemedicine: endoscopic surgery across 9300 km
Breakthrough for telemedicine: Surpassing a distance of 9,300 kilometers, surgeons from Hongkong and Zurich successfully performed an endoscopic procedure in an animal model.
News • Circadian-based therapeutic strategies
Cancer drugs more effective when the time-of-day is right, study finds
The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.
News • Automated tissue analysis
Digital pathology: AI platform to improve lung cancer diagnosis
Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.
News • Neuroblastoma diagnosis without anaesthesia
New PET/CT technique improves brain tumour detection in children
To diagnose neuroblastoma in children, lengthy scans and anaesthesia are often required. A new PET/CT imaging technique could deliver faster results without sedation for the paediatric patients.
News • Antibiotic resistance control
Better tracking of AMR hospital bacteria
Infections caused by antibiotic-resistant (AMR) bacteria are a major issue in hospitals. A new technique aims to effectively track all types of relevant microorganisms simultaneously.
News • Time loss vs. life expectancy gains
Dialysis: Is the tradeoff always worth it?
New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.
News • COLO-DETECT trial
Bowel cancer: AI improves early detection
Artificial intelligence (AI) can be used to great effect in colonoscopies to spot abnormalities potentially leading to bowel cancer. This is the result of the recently completed COLO-DETECT trial.
News • Promising research on oral rinse-based test
Wash, rinse – detect head and neck cancer?
Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.
News • Combined chemo and radiotherapy
Promising treatment for rectal cancer to avoid surgery
When a person is diagnosed with rectal cancer, part of the bowel is often removed, often resulting in the need for a stoma or problems with bowel control. A new therapy could help avoid this surgery.
News • Glycopeptide probes for antibody detection
New method speeds up pancreatic cancer detection
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
News • Prevention of surgery complication
Sterilization: cut or remove fallopian tubes?
Women whose Fallopian tubes are removed during sterilization have only marginally more surgical complications than those whose tubes are simply cut, a study shows.
Article • AI is key
Lung cancer screening initiatives across Europe
Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.
News • Recurrence timeframe analysis
Breast cancer radiotherapy: new insights on duration of protective effect
After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.
News • Genome and transcriptome analysis
Colorectal cancer prognosis derived from genetic signatures
Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.
News • Non-invasive risk assessment
Prostate cancer: avoiding unnecessary biopsies with AI
Combining risk markers, systematic evaluation of MRI images and AI, researchers aim to predict the risk of prostate cancer more accurately than before. This could save many patients from a biopsy.
News • Image analysis
Deep learning model detects prostate cancer on MRI scans
The interpretation of prostate MRI is notoriously difficult. Annotating AI shows promise to help improve diagnostic performance through increased cancer detection rates with fewer false positives.
News • Macrocyclic hybrid probe
New dual PET/MRI contrast agent to enhance kidney diagnostics
A new type of contrast agent for use in both MRI and PET imaging has the potential to significantly enhance diagnosis and subsequent treatment, particularly for kidney diseases and tumors.
News • Promising study results
Cancer of Unknown Primary: on the way to targeted therapies
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
News • Basal cell carcinoma diagnostics
BCC: AI helps identify aggressive types
Dermatologists could benefit from a new algorithm that can help recognize patients with a highly aggressive form of basal cell carcinoma (BCC) of the face.
News • Brain cancer research
Glioblastoma: Surprising find of immune cells
Researchers discovered islands of highly potent immune cells in the vicinity of glioblastomas. This may open up prospects for new therapies for these aggressive brain tumours.
News • Lower dose, improve tolerability, retain efficacy
Prostate cancer therapy: benefits of therapy deescalation
Radiotherapy of prostate cancer often comes with side effects, causing some patients to discontinue treatment. New research shows the benefits of at lowering the dose over subsequent treatment cycles.
News • Tumor assessment via chromatin imaging
From DCIS to IDC: AI identifies breast cancer stages
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
News • Concerns about hurried adoption
Survey: Is medical AI taking over too quickly?
The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.
Opinion article • Wearable medical devices
Sweat analysis reveals a wealth of health information
Diagnosis and monitoring medical conditions, including cancer, diabetes, heart disease, and infections: In this opinion article, Alix Joseph (Linxens) explores the potential of sweat analysis.
News • Hydrogel solution
Breakthrough in fridge-free storage of medicines
Many medicines require cold storage, which is a challenge for infrastructure and sustainability. Now, researchers designed a hydrogel protecting therapeutics at temperatures as high as 50°C.
News • Focus on ferroptosis
Major step towards a treatment for metastasis
Researchers have discovered an Achilles heel of migratory metastatic cells: They now investigate how the cell death mechanism ferroptosis can be utilized for future cancer treatments.
News • Immunology
“One and done”: promise for a universal influenza vaccine
New research reveals a promising approach to developing a universal influenza vaccine that confers lifetime immunity against an evolving virus considered most likely to trigger the next pandemic.
News • Public survey on medical conditions
Cancer seen as #1 health concern, AI as solution
Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.
News • Electronic prompt in the EHR
‘Nudging’ surgeons away from breast cancer overtreatment
Sentinel lymph node biopsies can help detect breast cancer – but not every patient benefits from the procedure. New research finds that a simple EHR prompt can prevent unnecessary surgery.
Article • Delivering more efficient healthcare
How teleoperation is changing radiology
As opportunities for teleoperations rapidly expand within radiology, the concept is being deployed across an array of modalities to deliver more efficient healthcare. A range of speakers covered the topic of ‘Teleoperations in radiology’ at ECR2024, discussing its benefits in applications in MRI, ultrasound, during the social restrictions of the Covid-19 pandemic and military use. However,…
News • Diffuse Large B-Cell Lymphoma (DLBCL)
Personalised simulations predict outcomes for blood cancer treatment
Using genomic sequencing data, researchers have created personalised simulations of individual patients that can quantify the impact of genetic mutations on cancer cell behaviour.
News • Tailored chatbot
Customized ChatGPT to advance digital pathology
New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.
News • Tumour infiltrating lymphocyte measurement
Breast cancer: AI tool predicts which DCIS cases become invasive
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
News • Taxane-induced peripheral neuropathy
New tool predicts nerve damage after breast cancer chemotherapy
Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.
News • Focus on microproteins
Researchers find potential target for liver cancer vaccine
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
News • HPV oncoprotein quantification
Urine test improves cervical cancer early detection
A new test shows promise in making cervical cancer screening more accessible and less invasive by detecting oncoproteins of the human papillomavirus (HPV) in urine samples.
News • Circulating tumor extracellular vesicles
Metastatic prostate cancer: better monitoring with new liquid biopsy method
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
Article • Institutional setup guide at SNMMI 2024
How to establish a hospital theranostics treatment centre
The nuclear medicine global market is projected to see a significant increase in the coming years, with the lion's share being attributed to radiotherapeutics. So, how to set up a dedicated theranostics centre? At the annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Toronto, Ontario, an entire session was dedicated to planning logistics, radiation safety, and…
News • Adaptive mutability
How bowel cancer flips the switch to avoid immune detection
Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.
News • Research on physical conditions
Exploring the link between obesity and cancer risk
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
News • The role of tissue stiffness
Pancreatic cancer: new approach could reverse chemo resistance
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
News • Diabetes, hypertension, and more
AI reads facial temperature for early diagnosis of metabolic diseases
Measuring temperatures in different face regions could be used to earlier detect chronic illnesses, such as diabetes and hypertension. Researchers now show the potential of an AI-based approach.
Article • Compared to laparoscopy
Robotic surgery improves colorectal surgery outcomes
When colorectal surgery was first performed with robotic assistance in 2014, the procedure was questioned about safety, efficacy, and outcomes. Today it is an established option. Well-trained surgeons use robotic surgical systems confidently. Numerous clinical studies have verified its intraoperative benefits for patients and surgeons alike, as well as very positive outcomes for patients.
Sponsored • Diagnostic imaging in Rome
Brand-new nuclear medicine department equipped with advanced Total-Body PET/CT system
The new Nuclear Medicine Department of the San Pietro Fatebenefratelli Hospital was inaugurated in Rome. The Department was inaugurated with the online intervention of Health Minister Orazio Schillaci and in the presence of Maria Tripodi (Undersecretary at the Ministry of Foreign Affairs and International Cooperation), Antonello Aurigemma (President of Lazio Regional Council).
News • New insights on shape and toxicity
Small, but mighty – how gold nanoparticles (actually) kill cancer
Smaller kills faster – this is what was previously thought about gold nanoparticles used to fight cancer cells. However, new research reveals a more complex picture of these interactions.
News • "Candycrunch"
AI and mass spectrometry to find cancer clues at lightning speed
Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.
News • Vital mechanism discovered
Promising approach to prevent breast cancer recurrence
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
Article • Professional perspectives
Theranostics: A career opportunity for Nuclear Medicine Technologists
What is an advanced clinical practitioner (ACP) and why should nuclear medicine technologists strive to become one? At the 2024 annual meeting of the SNMMI in Toronto, ACP Luisa Roldão Pereira outlined the position and its importance in the clinical context.
News • Digital support
New app triples chance to quit smoking
Finnish researchers found that using a mobile application based on cognitive behavioral therapy can significantly boost success rates of people attempting to stop smoking.
Article • Addressing diagnostic backlogs
Harnessing the power of AI for women's health
Although the Covid-19 pandemic is behind us, healthcare facilities continue to experience workflow challenges and resource constraints impacting women’s health and a patient’s ability to receive a timely diagnosis. Clinical specialties like breast radiology and cytology are especially susceptible to these issues and continue to experience backlogs, which impact their ability to deliver timely…
News • Iontronic technology
Slowly but steady gets the brain tumour
Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.
Article • Challenges and opportunities
Molecular pathology in Europe: in search of standardization
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
Article • Benefits of seated placement
Patient positioning during cancer radiotherapy: Upright is alright
The concept of delivering radiation therapy to cancer patients seated in an upright position is undergoing a major resurgence. Evidence is already highlighting that patients feel more comfortable seated upright and enjoy better communication with radiotherapists during their care. In addition, there are indications of less internal organ movement, enabling more accurate treatment delivery.…
News • Reduction of greenhouse gas emissions
Telemedicine for more sustainable cancer care
Cancer care that utilizes telehealth and local care would generate 33.1% less greenhouse gas emissions than the traditional model, new research finds.
Sponsored • All in one scan
World's First Total-Body PET/CT with 194 cm Axial FOV installed in Europe
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
News • Impact on mammography performance
Breast cancer screening: better detection, fewer false positives with AI
Using artificial intelligence (AI), breast radiologists in Denmark have improved breast cancer screening performance and reduced the rate of false-positive findings.
News • Antibacterial protein as therapeutic target
Pancreatic cancer: new approach for immunotherapy
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
Sponsored • Brachytherapy in LAPC patients
Innovative Avenue of Treatment – Internal Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer
In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.
News • Foetal development research
Tracing back the origins of AML childhood leukaemia
Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.
News • Neuropathology
Technology offers new insights into pediatric brain tumors
A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.
News • Integration of microanalysis chips
Establishing microfluidic control technology for blood testing devices
A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.
News • Success of aRCC treatment
New biomarker to better predict immunotherapy response in kidney cancer
Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.
News • Insights into ink
Study links tattoos with increased lymphoma risk
A new study suggests that tattoos could be a risk factor for cancer in the lymphatic system, or lymphoma. Now, the researchers underline the need for more research on the topic.
Article • Pros and cons of diagnostic techniques
Liquid biopsy vs. tissue biopsy: Getting the best of both worlds
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
News • Stratification approach
Using national health data to predict cancer risk
Scientists show that health registry data can be used to predict individual risks for the 20 most common cancer types. This could help to identify high-risk groups and enrol them for screenings.
News • UK study confirms
Lung cancer screenings: benefits across all socioeconomic groups
Lung cancer screenings save lives – especially for those who live in economically deprived areas, a new study confirms. The researchers further demonstrate the benefits of using low-dose CT imaging.
News • Impact of patient characteristics
Breast cancer AI: unequal performance across ethnicities and age groups
Current AI systems for detecting breast cancer from mammography exams are more likely to produce false-positive results in black women and older patients, a new study finds.
News • CT-Derived Functional Imaging
CTFI: Enabling CT lung diagnosis without contrast
Diagnosing lung conditions such as pulmonary embolism is more challengenging when a patient cannot tolerate contrast agents. Now, a new software solution is addressing the issue.
News • Hydrogel catalyst
Breaking down alcohol in the body: Researchers develop "detox gel"
Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.
News • Research on DNA danage
Surprise finding on cancer cell death to impact therapies
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
Article • Advancements in endoscopy
Enhancing diagnosis and disease monitoring for ulcerative colitis
Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.
News • Clear cell renal cell cancer
Same-day imaging for ccRCC kidney cancer with new PET agent
A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).
News • Three-dimensional tissue processing
Pathology performs leap into 3D with AI
Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.
News • 6.5 million European funding
Fighting cancer with artificial cells and tissue
Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.
News • Leukemia MRD after chemo
AML: Residual cancer testing as an important safeguard
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
News • On-demand reversibility
Anticoagulation with an ‘on/off’ switch
Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.
News • Opportunity for new treatment approaches
Atherosclerosis and cancer share surprising similarities, study finds
In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.
News • Ciliopathy reseach
Rare lung disease: genetics reveals cause of PCD
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
News • MRSA and other infections
Researchers develop vaccine to fight antibiotic resistance
Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.
News • Urine-based diagnostics
New prostate cancer test to help avoid unnecessary biopsies
US researchers have developed and validated a new urine-based test for prostate cancer, which was shown to meaningfully reduce unnecessary prostate biopsies while providing highly accurate detection.
News • Research on large foundation models
Reducing bias in pathology AI
A study highlights performance differences in computational pathology systems, depending on demographic profiles associated with histology images. The researchers also propose a way to fix this bias.
News • Nuclear medicine
Prostate cancer: New SPECT/CT technique for greater treatment precision
A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.
News • GMAI for cancer treatment
Generalist Medical AI: Experts propose legal guardrails
Generalist Medical Artificial Intelligence (GMAI) models pose a significant challenge to current regulatory frameworks. Experts discuss how regulation of these models could work in the future.
News • Novel probe assesses cell stiffness
A 3D endo-microscope for early cancer diagnosis
Stiffness in tissues can be a valuable indicator of cancer formation. Now, researchers have developed a microscopic probe to perform histology at the single cell level inside the human body.
News • Atypical teratoid/rhabdoid tumours
Understanding the development of AT/RT brain cancer in children
Unlike most tumours, atypical teratoid/rhabdoid (AT/RT) tumours develop very quickly. Now, researchers explored the mechanisms of these aggressive brain tumours that mainly affect young children.
News • Voice box cancer treatment
Laryngeal cancer: AI software to better predict outcomes
Experts at Newcastle University have discovered artificial intelligence can be used to analyse medical imaging from CT scans, which is aimed at predicting survival in patients with laryngeal cancer.
News • Research on biomechanics
Tumour 'softness' can drive aggressiveness of breast cancer
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
Article • Lesion detection and mammographic texture analysis
Dual AI model to optimize breast cancer risk assessment
A team of Danish and Dutch researchers has combined an AI diagnostic tool with a mammographic texture model to improve the assessment of short- and long-term breast cancer risk. This new approach represents a significant step forward in refining the ability to predict the complexities of breast cancer risk.
News • Mechanistic subtypes
The telltale traces long Covid leaves in the blood
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Article • Pharmaceutical research
Boosting biomarker detection with digital pathology
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
News • Microbial influence on treatment
Study explores the role of bacteria in cancer
Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.
News • Promising secretory granules
New micromaterial to fight cancer with nanoparticle-targeting
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
News • Biparametric scan
Prostate cancer screening: two-part MRI is enough, study shows
A three-part ‘multiparametric’ MRI of the prostate is standard of care in the UK for patients suspected of having prostate cancer. Now, a study shows two-part scans are sufficient for diagnosis.
Article • Prostate cancer treatment
MR-guided radiotherapy: a potential game changer
Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
News • Preventive blood test
Prostate cancer screening: Study advocates 5-year-interval
How often should men get checked for their level of PSA, a marker for prostate cancer? A German study involving over 12,500 men shows that a five-year interval between tests is safe.
News • Omitting axillary lymph node removal
Breast cancer trial explores benefits of less extensive surgery
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
News • Osteosarcoma model
Bone cancer prognosis enhanced via deep learning
Osteosarcoma is the most prevalent malignant bone tumor. Now, researchers have developed a machine-learning model to predict the density of viable tumor cells after surgery and chemotherapy treatment.
News • Minimally invasive procedure
Microwave ablation: alternative to thyroid cancer surgery
Papillary thyroid carcinoma (PTC) is often treated with surgical resection, which often comes with significant side effects. Now, a new study points to a minimally invasive alternative.
News • Technique comparison study
Oesophageal cancer: standard or keyhole surgery?
When treating oesophageal cancer, surgeons may have a preference towards either open surgery or keyhole techniques. Now, a study explored superiority of one over the other in terms of recovery time and complications.
News • BRCA1 and BRCA2 malfunctions
Targeting 'exhausted' immune cells to prevent breast cancer
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
News • Bioinformatics
New tool identifies chromosomal instability in cancer cells
A new detection tool is designed to contribute to improving tumour research and classification by identification and quantification of chromosomal instability in the nuclei of cancer cells.
News • Implant and app
New device monitors bladder fullness
A new bioelectronic sensor enables continuous monitoring of bladder function. This could be a game-changer for people with paralysis, spina bifida, bladder cancer or end-stage bladder disease.
News • 3D mammography
Trial shows benefits of digital breast tomosynthesis in breast cancer screening
A clinical trial has revealed the effectiveness of '3D mammography' in reducing by almost half the incidence of interval breast cancer appearing between two rounds of screening.
News • Promising study
Pre-operative PET-MRI to improve breast cancer treatment
A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.
News • Tumor proliferation insights
Computational model simulates biomechanical growth of breast cancer
A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.
News • Potential for screening and treatments
Study links bacteria subtype to colorectal cancer growth
A specific subtype of a microbe commonly found in the mouth has been identified that is able to travel to the gut and grow within colorectal cancer tumors, driving cancer progression.
News • Tumor organoid platform
Personalized 3D bioprinting to advance gastric cancer treatment
Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.
News • Characterization of cancer relevant genes
Breast cancer: Researchers take a deep dive into cell lines
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
News • Noninvasive stratification
Multiplex PET helps doctors 'see' bowel cancer
Multiplex PET imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, according to scientists in Glasgow.
News • Heart rhythm disorder
Stroke prevention: experts recommend routine atrial fibrillation testing
Atrial fibrillation is the most common heart rhythm disorder globally. Patients at high risk for AF, such as those with heart failure or prior stroke, should be tested at every GP visit, experts say.
News • Tissue analysis tool
'Smart scalpel' to help remove brain tumours
Researchers have developed the 'iKnife', a smart scalpel that is able to recognise healthy tissue from brain tumour in seconds as it cuts, with more than 98% accuracy.
News • Chemotherapy and novel surgery technique
Study explores new approach to 'inoperable' pancreatic cancer
US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.
News • Ovarian, testicular cancer
Germ cell tumours: Lower survival in women
Women with a type of ovarian cancer known as germ cell tumours have a worse prognosis than men with similar tumours. The five-year survival rate was 98% for men, but 85% for women, a new study finds.
News • Voxel-wise classification
Deep learning tool uses MRI to enhance brain tumor diagnosis
A novel AI-based, non-invasive diagnostic tool enables accurate brain tumor diagnosis, outperforming current classification methods. The tool leverages MRI information to aid clinical decision making.
News • Review calls for immediate action
Medical devices: prone to unfair bias, study finds
Pulse oximeters delivering poorer results in people with darker skin tones, underdiagnosis of cardiac conditions in women: some medical devices are not as fair as the ought to be, a new review finds.
News • Radiofrequency electromagnetic radiation
Do long calls on mobile phones increase brain cancer risk? Study says no
Holding a mobile phone close to the head for an extended amount of time has long been connected to brain cancer. Now, a new study found no hints for an increased risk.
News • Interpretable machine learning system
AI to detect colorectal cancer from pathology slides
Researchers work on the first prototype that applies AI to colorectal diagnosis. The prototype achieved a diagnostic acuity of 93.44% and a sensitivity of 99.7% in the detection of high-risk lesions.
News • Accurate detection and removal
Radioguided surgery to treat metastatic lymph nodes in prostate cancer
Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.
News • Memory impairment
"Chemo brain": gamma waves may be key to protection
Researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating memory impairment and other cognitive effects of chemotherapy.
News • Reimbursement and access
Lung cancer care: addressing inequalities across Europe
When it comes to lung cancer care, patients in Europe face significant differences depending on the country they are in. Researchers from Amsterdam analysed the landscape.
Article • Joint action
A pan-European effort to tackle cancer and NCDs
This February, the Norwegian Institute of Public Health officially launched the ‘Joint Action on cancer and other non-communicable disease prevention project‘ (JA PreventNCD). In the four-year-initiative, 22 EU member states plus Iceland, Norway and Ukraine have joined forces to combat the increasing burden of non-communicable diseases (NCDs) across national borders.
News • Personalised oncology
New platform to significantly reduce cancer drug testing and screening time
In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.
News • Cortisol sampling from blood
Paving the way for better diagnosis and treatment of endocrine diseases
A team of researchers has discovered a new method of measuring levels of cortisol directly from a blood sample - a significant step forward in diagnosis and treatment of a wide range of diseases.
News • Women's health imaging
Breast cancer: MRI surveillance reduces mortality in BRCA1 high-risk women
An international study has revealed that MRI monitoring in women with mutations in the BRCA1 genes significantly reduces breast cancer mortality without the need for preventive mastectomy.
News • Revealed by AI
Prostate cancer: more than just one disease
Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer which could revolutionise how the disease is diagnosed and treated in the future.
News • Radiology congress
Hologic reveals AI research at ECR 2024
Hologic, Inc. unveils new research in artificial intelligence (AI) and offering innovative educational opportunities at the annual European Congress of Radiology (ECR) in Vienna, Austria.
News • Telesurgery
First robot-assisted remote radical distal gastrectomy with 5G technology
A potential milestone for telesurgery: a team of researchers from China reported the first robot-assisted remote radical distal gastrectomy performed using 5G communication technology.
News • Diabetes management
Reducing blood sugar levels with red light
Researchers have found a surprising method to reduce blood glucose levels in a person: Shining red light on their back. This could help control diabetes without medication.
Article • Imaging in characterisation and classification of tumour types
Taking a closer look at breast cancer
Breast cancer has no “one size fits all” therapy approach: subtypes differ significantly in malignancy, progression, and treatment response. Therefore, the more is known about the type of carcinoma in a patient, the better the outcome. At the annual scientific EUSOBI meeting in Valencia, Dr Ramona Woitek pointed out the potential of novel imaging techniques and computational image analysis…
Article • Additional findings from the MIPA study
Benefits of preoperative breast MRI
Ordering preoperative breast MRI exams of diagnosed breast cancer patients used to be controversial: Did they aid surgical planning better than the combination of mammography and breast ultrasound? Or did their findings cause overtreatment, specifically mastectomy, when breast-conservation surgery would have sufficed? New research has now settled the issue.
Article • New system combines nanotechnology and ultrasound
Reducing over-treatment of rectal cancer
An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.
News • Alternative to endoscopy
Sponge-on-a-string test as less invasive method to diagnose oesophageal cancer
A new test to help diagnose Barrett’s oesophagus – a condition that can lead to oesophageal cancer – has reduced the need for invasive endoscopy in thousands of low-risk patients.
News • Fertility research
Researchers produce testicle organoids in the lab
A research team created "laboratory testicles" that may significantly advance understanding of the mechanisms involved in sex determination and provide solutions for male infertility.
News • Metastasis susceptibility
How chronic stress spreads cancer
Chronic stress can have a significant impact on health, from an increased risk for heart disease to a greater susceptibility of cancer metastasis. New research points out the underlying mechanisms.
News • Research on radiation interaction
Lung tissue model to increase cancer radiotherapy safety
Cancer patients receiving radiotherapy run the risk of injuring their lungs. This can lead to conditions like pneumonitis and fibrosis. A new cell-by-cell model can help make treatments safer.
News • European Congress of Radiology
ESR and GE HealthCare team up once more for ECR 2024
GE HealthCare and the European Society of Radiology (ESR) renew their collaboration for the upcoming European Congress of Radiology (ECR) from February 28 to March 3 in Vienna.
Article • Imaging controversial
MRI breast cancer screening of high-risk women: benefits outweigh drawbacks
Breast MRI is increasingly being used as a primary breast cancer screening exam for young women. It brings benefits in women with dense breasts, who are at an elevated risk of developing breast cancer. The technique is also being ordered as a supplemental screening exam following mammography or breast ultrasound for women of all ages at high risk. But use of breast MRI as a screening tool is…
News • Pan-cancer proteogenomics
Characterizing the immune landscape in cancer
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
News • Saliva test device
Breast cancer screening: Biosensor could offer alternative to diagnostic imaging
A newly-developed biosensor could be an alterative to MRI and mammography for breast cancer screening. The handheld device uses saliva on test strips to determine whether cancer is present.
News • Focus on protein GDF15
Newfound mechanism could improve efficiency of diabetes treatments
Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.
News • Histological transformation
How lung cancer can transform into another type
Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.
News • Molecular method
Low-dose PEM imaging to transform breast cancer detection
A new breast imaging technique provides high sensitivity for detecting cancer while significantly reducing the likelihood of false positive results, according to a new study.
News • Equipment and technology fair
Labs Expo announces extensive and engaging programme
Registration is now open for the Labs Expo Laboratory Equipment and Technology Fair (March 19-20), the premier event in the laboratory industry in Poland.
News • Portable diagnostic tool
Breast cancer detection: New program tracks tumour heat
Researchers in Singapore have developed an AI-based software to assist in the early detection of breast cancer. Using thermal imaging, the program assesses the malignancy of a tumour.
News • Chemotherapy and cancer drugs
‘Heart-on-a-Chip’ to test cardiotoxicity of treatments
Chemotherapy can be toxic to heart cells. To help protect the hearts of cancer patients, Cedars-Sinai investigators have created a three-dimensional “heart-on-a-chip” to evaluate drug safety.
News • Restoring responsiveness
New method could crack treatment-resistant prostate cancer
Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.
Article • During lumpectomy
Fluorescence-guided surgery identifies breast cancer in margins
Breast surgery is a traumatic experience for a woman, no matter whether breast-conservation surgery (BCS) or a mastectomy. Trauma levels are greatly enhanced, if pathological evaluation findings of an excised breast tumour following a lumpectomy suggest that additional cancer may still be in the margins, and a second surgical procedure is required. A new system with the ability to accurately…
News • Appeal for better approval conditions
AI in personalised cancer medicine: “A fundamental change is needed”
AI technology holds promise for personalised cancer therapies. However, rigid and slow approval requirements impede its introduction, say experts – and point out how this might be changed.
News • Inequalities in diagnostics, treatments and care
Cancer care in Europe: alarming gaps remain
On the occasion of World Cancer Day on February 4, the Union for International Cancer Control points out persisting care gaps across Europe due to disparities in income, education and other factors.
News • Increasing cell visibility
Making cancer easier to find and destroy for the immune system
Researchers in Japan and the US have developed technology to robustly augment the amount of MHC class I molecules in cancer cells. This makes them easier to find and destroy for the immune system.
News • Accelerated sample analysis
Digital pathology cleared for use in cancer screening programmes
Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.
Article • Addressing an unmet need
MCED: a simple test for widespread early detection of cancer
Academic labs and biotech firms pioneer multi-cancer early detection with emerging technologies. Screening for multiple cancers with a simple blood or urinary draw could be a game-changer. Two research teams in particular have advanced the field.
News • Elimination of senescent tumour cells
Study: Immunotherapy makes anti-cancer chemotherapy more efficient
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
News • Blood-based diagnosis of glioblastoma
Sparing brain cancer patients from undergoing risky surgery
A simple blood test could help diagnose patients with glioblastoma, the deadliest form of brain cancer, sparing them from undergoing invasive and highly-risky surgery, report UK researchers.
Article • UK research project
"Our Future Health": Shifting from curative to preventive care
As a result from better living standards and medical advances, population longevity increases – a development which, paradoxically, current healthcare systems are ill-prepared for, Sir John Bell points out. The UK’s Our Future Health programme, which he chairs, exemplifies the paradigm shift to a prevention-centered healthcare approach.
News • Molecular machines
Killing cancer cells: the 'jackhammer' approach
Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.
News • Mammacarcinoma research
Study pinpoints breast cancer ‘cells-of-origin’ in high-risk women
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
News • Men's health
Gynaecomastia linked to heightened risk of death
Men with gynaecomastia (non-weight-related enlarged breast tissue) may be at heightened risk of an early death before the age of 75, suggests the first study of its kind.
News • Urea-powered machines
Nanorobots to reduce bladder tumours by 90%
New research demonstrates how tiny nanomachines could greatly reduce bladder cancer by precisely targeting the tumour and attacking it with a radioisotope carried on their surface.
Article • Experts explore impact of technology
AI in radiology: helper or bane of society and the environment?
The climate crisis and AI – arguably two of the most hotly-debated and relevant topics of our time – share an intricate relationship: While computation of complex AI routines commands an immense carbon footprint, it is these algorithms that might be the very key to mitigate the effects of global warming. In a dedicated session at ECR 2023, radiologists explored the societal and environmental…
News • Promising study in mice
Exploring the potential of mRNA technology for rare diseases
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
News • Finding therapy-relevant genetics
Leukaemia: AI provides support in diagnostics
Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.
News • Water exchange detection
New MRI-based method measures tumor malignancy
An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.
News • Point-of-care diagnostic platform
Inhalable sensors for early lung cancer detection
Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.
News • Promising approach
Researchers use nanodrones for targeted cancer treatment
A research team has successfully developed “NK cell-engaging nanodrones” capable of selectively targeting and eliminating cancer cells, offering a potential solution for intractable cancer types.
News • Fullness simulator
This vibrating, ingestible capsule might help treat obesity
When your stomach is full after a large meal, certain receptors are activated to tell the brain. A newly developed capsule could provoke this fullness signal early, potentially helping with treating obesity.
News • Technology assessment
AI in medical research: Promise and challenges
A powerful tool, but the need for human judgment remains: In an editorial published in PNAS Nexus, Monica M. Bertagnolli assesses the promise of AI and machine learning to study and improve health.
News • Expert prediction of financial aspects
Why precision medicine will save lives (but not costs)
While genetic information may lead to better treatments, promises of cost savings are unfounded. Instead, a large additional bill is more likely, according to University of Copenhagen researchers.
News • "Gene scissors" vs. sickle cell disease
FDA approves first CRISPR/Cas therapy
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
News • CTC, ctDNA and exosomes in PCa management
Prostate cancer: Blood-based liquid biopsies yield valuable information
US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.
News • Tissue oxygenation
Photoacoustic imaging for better diagnoses of ovarian cancer
Researchers and clinicians at Washington University in St. Louis found a way to improve diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes.
News • Cytokine reference
New “dictionary” reveals suprising complexity of immune responses
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
News • Friend and foe in one
Breast cancer: The paradoxical role of white blood cells
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
Article • Knowledge gaps in gender medicine
Covid-19 and sex: higher mortality of male patients
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
News • SCN tumor development
How prostate cancer grows aggressive to evade treatment
In a new study, UCLA researchers demonstrated how small cell neuroendocrine prostate cancer tumor cells can arise from less aggressive prostate tumors.
News • Using low-frequency electromagnetic fields
New method can detect early-stage breast cancer in two minutes
University of Waterloo researchers are pioneering a method to detect breast cancer in women early enough for them to receive life-saving treatment.
News • Based on image-based flow cytometry
Rapid test to predict severe Covid-19 infections
Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…
News • WSI-based analysis
AI-driven classification of diffuse gliomas skips molecular testing
Research from Shenzhen proposes an integrated diagnosis model for automatic classification of adult-type diffuse gliomas directly from annotation-free standard whole-slide pathological images.
News • Encouraging results of DARS trial
A ‘new gold standard’ for head and neck cancer radiotherapy
New research suggests a new approach to precision radiotherapy can reduce the risk of swallowing problems for patients, without impacting the success of treatment.
News • Flexible materials for imaging
'Bendy' X-ray detectors could revolutionise cancer treatment
New tissue-equivalent materials developed at the University of Surrey could pave the way for a new generation of flexible X-ray detectors, with potential applications in cancer treatment.
News • Opportunistic screening using chest X-rays
AI identifies non-smokers at high risk for lung cancer
Incidence of lung cancer among people who never smoked is rising. A new AI tool opens the door for opportunistic screening for this group, using existing chest X-rays in the electronic medical record.
Article • Trade fair presence
Taiwan blends tech and tradition at Medica 2023
AI features for automation, integrated systems and more: the role of medical technology has never been as vital as today, and MedTech companies from Taiwan are putting their best foot forward to contribute. At the 2023 Medica trade fair, visitors of the Taiwanese pavilion not only had the opportunity to see the latest medical products on display, but also get acquainted with Taiwanese culture in…
News • Lab model to find treatments for stroke, dementia
Finding (and fixing) vascular leaks in the brain
Using small blood vessels grown in the lab, researchers discover how vascular leaks leading to dementia and stroke emerge – and how this damage might be fixed.
News • Clinical marketing
Specialize or diversify? Study advises on hospital portfolio strategy
Should a hospital cover all specialties, or focus to excel at one area? US researchers have assessed the impact of a hospital’s portfolio strategy on patient demand.
News • Study on NHS DPP
Diabetes prevention: UK programme may have global impact
A nationwide programme to reduce the risk of developing diabetes in the United Kingdom is proven beyond reasonable doubt to work, a new study reveals.
News • Nuclear medicine
Prostate cancer: staging issues in bone scans compared with PSMA PET
Bone scans have been found to overstage prostate cancer at initial staging compared to prostate specific membrane antigen (PSMA) PET, according to new research.
Article • Latest advances
Lab-on-a-chip systems in 2023: The micro-lab revolution
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
News • Study confirms association
CT scans in young people increase cancer risk
A multinational study confirms a strong and clear association between exposure to radiation from CT scans in young people and an increased risk of blood cancers.
News • PDAC subtype classification
Attacking the roots of pancreatic cancer
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
News • 20-year study shows benefits
Lung cancer: screening with low-dose CT sharply improves long-term survival
Diagnosing early-stage lung cancer with low-dose CT screening dramatically improves the long-term survival rate of cancer patients, a large-scale, 20-year international study shows.
News • Prognostic model
New urine-based test offers hope for bladder cancer patients
In a new study, researchers from Fudan University have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.
News • Ultraviolet cell visualisation
'Seeing' cancer though the eyes of a butterfly
Inspired by the enhanced visual system of butterflies, researchers have developed an imaging sensor to “see” into the UV range for differentiating between cancer and normal cells.
News • Interaction with cancer patients
Experts raise ethics concerns posed by patient-facing AI in oncology
Bioethics researchers call on medical societies, government leaders, clinicians, and researchers to work together to ensure AI-driven healthcare preserves patient autonomy and respects human dignity.
News • Screening study
Mammography screening: false positive results increase breast cancer risk
Mammography screening is vital in breast cancer prevention, but about 3% of women receive a false-positive result. This not only causes worry, but also increases risk of developing breast cancer.
News • RENACER repository
Brain cancer tissue samples to gain new insights
A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.
Article • Need for diversity in training datasets
Artificial intelligence in healthcare: not always fair
Machine learning and AI are playing an increasingly important role in medicine and healthcare, and not just since ChatGPT. This is especially true in data-intensive specialties such as radiology, pathology or intensive care. The quality of diagnostics and decision-making via AI, however, does not only depend on a sophisticated algorithm but – crucially – on the quality of the training data.
News • VITT reseach
Cause for rare, but deadly vaccine-related blood clotting found
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
News • Surgical navigation system
Breast cancer localization: study puts new device to the test
A new device that acts like a GPS to locate and remove breast and lymph node tumors was tested for its safety and effectiveness in a feasibility study - with promising results.
News • Good killer cells
Cellular immunotherapy: a new approach against cancer
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.