Search for: "Cancer Research" - 250 articles found

Article • Insights and perspectives presented at ECR 2025

Nuclear medicine: Innovations, challenges, and new horizons

Nuclear medicine (NM), one of the more mature technologies of diagnostic imaging, has been experiencing a rebirth in innovation and interest. The increasing prevalence of cancer, in part the result of improved diagnostic tests, an aging global population, and greater longevity, has created a robust demand for nuclear medicine. At the European Congress of Radiology (ECR) in Vienna, presenters…

News • Bioengineered scaffolds

New hydrogel to improve CAR T immunotherapy

Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.

News • Adversarial robust image processing

Defense system protects medical digital twins from cyberattack

Medical digital twins can help predict diseases, but are vulnerable to cyberattacks that can lead to incorrect diagnoses. Researchers have developed a new defense system to address this threat.

News • Pulsed infrared light to enhance diagnostics

Finding the ‘fingerprints’ of cancer

New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.

News • Cardio-diagnostics for untrained users

Heart disease screening made easy with new handheld device

A new device for people with or without medical training could be used as an easier, more forgiving alternative to stethoscopes to accurately detect valvular heart disease (VHD).

News • Study on Staphylococcus aureus

Understanding bacterial antiviral defenses to tackle antibiotic resistance

In a new study, researchers show that the emergence of antibiotic resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.

News • Swedish national initiative

Precision omics to boost data-driven medicine

The new national Precision Omics Initiative Sweden (PROMISE) aims to generate and integrate extensive molecular data to create a model for precision medicine implementation for Sweden.

News • Targeting early versions

A 'head start' in the race against pancreatic cancer

Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.

News • Lifestyle-related disease prevention

Soccer: an underrated champion of global health

Soccer is not only a fun and popular sport, but can also help prevent many lifestyle-related conditions, including diabetes, heart disease, obesity, several cancers, and mental health challenges.

News • Double Stokes polarimetric microscopy

New method to help accelerate cancer diagnosis

A new method to quickly and accurately analyze the structure of collagen in tissue shows promise to improve the diagnostics of cancer and other diseases.

News • Trial on selective surgery omission

Invasive breast cancer: surgery not always necessary, study finds

Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant chemotherapy and standard radiotherapy, new research finds.

Article • Digital pathology discussion panel

The AI tools pathologists want and need

The evolving role of AI tools in digital pathology was explored at an open discussion during the annual Digital Pathology and AI Congress in London with a high-level panel of practitioners looking at current and future technology options. The panel of pathologists, scientists and academics from Europe and the USA assessed the tools they currently use and are available to them, and those they…

News • Systemic cell rewiring

How midkine helps tumours evade immunotherapy

Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.

News • Study on incidence and risk factors

Many breast cancers are detected between screenings

3 out of 10: Mammography screening has been shown to be effective in reducing breast cancer mortality. Still, many cancers are diagnosed between screening rounds, a new study shows.

News • Cardiac event marker

Coronary artery calcium score: useful regardless of age

A large new study of more than 40,000 patients finds that a zero coronary artery calcium score continues to be an accurate indicator of a low risk for a coronary heart event even as a person ages.

News • Mortality, CVD, cancer, and more

Weight loss protects (even when it's regained)

Losing weight is a great way to improve one's overall health. But, are these benefits gone once a person is gaining weight again? Not necessarily, a new study points out.

News • Alternative to MRI-guided biopsy

Micro-ultrasound to speed up prostate cancer diagnosis

To diagnose prostate cancer, an MRI-guided biopsy is often performed. Now, a study shows that micro-ultrasound is just as effective, cheaper and easier to use. This could help free up MRI capacities.

News • Machine learning analysis

Breast cancer: AI predicts metastasis from recurrence

The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.

News • HBV point-of-care identification

Hepatitis B: rapid diagnostic test to halt mother-to-child transmission

A new rapid diagnostic test can identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This could help prevent mother-to-child transmission during childbirth.

Video • Oloid-shaped magnet-driven probe

Virtual biopsy: tiny robot wobbles its way through the gut

Engineers developed a robotic probe that can generate high-resolution 3D ultrasound images from deep inside the gastrointestinal tract. The robot reaches its target with a unique kind of movement.

News • Study shows GP imaging benefits

Lung fibrosis: radiopharmaceutical improves diagnosis and monitoring

Nuclear medicine specialists have successfully used the radiopharmaceutical Ga-68-Trivehexin from Trimt to accurately diagnose patients with pulmonary fibrosis and concurrent lung cancer.

News • Pilot study on wearables

Telemonitoring t-shirt allows patients to return home earlier after urological surgery

Could a t-shirt with sensors reduce the time patients need to stay in hospital after a urological surgery? A recent pilot study suggests it might.

News • Review of colonoscopy CADe systems

AI for colon cancer detection: "Right now, this is version 1.0. We need version 4.0”

A rigorous review of evidence showed that AI-assisted technology helps identify colorectal polyps. However, its impact on preventing colon cancer remains unclear.

News • Deep learning-based CVD risk prediction

Mammography and AI open a new window into heart health

New findings show how AI-assisted mammography may not only reveal breast cancer, but can also assess calcium buildup in the arteries within breast tissue—an indicator of cardiovascular health.

Article • Freezing cancer cells

Cryoablation: A treatment option for low-risk early-stage breast cancer

Cryoablation, the destruction of malignant cancer cells by freezing them, is increasingly becoming an alternative to having conventional lumpectomy for patients diagnosed with early-stage, localised, low-risk breast cancer. Findings from numerous recent clinical trials show that cancer recurrence rates are very low and are comparable to breast conservation surgery (BCS).

News • Actionable genetic variants

Look into "Viking Genes" shows benefits of personalised health insights

A research project investigating the genetics and health of volunteers from the Hebrides, Shetland or Orkney shows how distinct genetic populations can benefit from tailored screening programmes.

News • Behavioural intervention study

Want to boost bowel cancer screening response? Add a deadline

Screening for colorectal cancer has proven effective for reducing mortality, but response rates are lacking. A new study finds that putting on the pressure can provide the necessary encouragement.

News • Triple-negative breast cancer

Novel radiotracer identifies TNBC biomarker

A new PET tracer has the potential to play a critical role in the diagnosis, treatment, and monitoring of aggressive triple-negative breast cancer (TNBC), improving clinical outcomes for patients.

News • Intrinsic electrical activity drives cancer progression

SCLC: Deciphering the unusual aggressiveness of small cell lung cancer

New research reveals that self-generated electrical activity of small cell lung cancer (SCLC) directly promotes tumor metastasis and progression. This may provide new avenues for future treatments.

News • Responsiveness of machine learning models

Will an AI recognize patient deterioration in the ICU? Not quite yet

Machine learning models fail to detect key health deteriorations in the ICU: a new study reveals that 66% of critical injuries in hospitals would go unnoticed if the current AI models were put to use.

News • Circulating tumor DNA analysis

Liquid biopsy helps reduce chemotherapy in colon cancer patients

For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.

News • Ionic liquid-carbon nanohorn complexes

Magnet-guided, laser-heated nanoparticles for precision cancer treatment

Japanese researchers have developed magnetic nanoparticles that can be directed to tumors using a magnet and then heated with a laser to destroy cancer cells while sparing healthy tissue.

News • LDCT rule-out

AI shows potential for workload reduction in lung cancer screening

A new study reveals that AI can accurately rule out negative low-dose CT (LDCT) scans, potentially reducing the workload of radiologists in lung cancer screening by up to 79%.

Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

News • Deep and ensemble learning improve performance

New AI tool surpasses previous methods in colorectal cancer tissue analysis

Researchers developed an advanced AI tool for automatic analysis of colorectal cancer tissue slides. The new model outperformed all predecessors in the classification of tissue microscopy samples.

News • Longitudinal image analysis

AI tool detects changes in series of medical images

Researchers developed an AI-based system which has has a broad ability to identify even subtle differences between medical images taken at different times, and to predict related outcome measures.

News • Field cycling imaging

FCI sees 'previously undetectable' cancer spread

Using a prototype field cycling imager (FCI) scanner to examine breast cancer tissue, scientists distinguish tumour material from healthy tissue with more accuracy than current MRI methods.

News • Promising method for cancer imaging

Using photon counting for fast color X-ray images

Photon counting detectors along with novel algorithms allow for more precise 3D visualization of different tissues and contrast agents by capturing X-rays at multiple energy levels simultaneously.

News • Aldosterone-producing adenomas

The surprising complexity of adrenal gland tumors

New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.

Article • Imaging modality comparison presented at RSNA 2024

Photon-counting CT advances identification of pancreatic cystic lesions

Pancreatic cystic lesions – indicating an increased risk of pancreatic cancer – are an occasional incidental finding in routine computed tomography (CT) abdominal imaging. New research suggests that the superior image quality of photon-counting CT (PCCT) can help detect more of these lesions. At the RSNA annual meeting, an expert outlined the benefits and limitations of the imaging technique…

News • Correlated diffusion imaging

AI makes breast cancer “glow” in MRI images

A new AI-enhanced technique makes breast cancer tissue “glow” on MRI scans. This not only improves breast cancer detection but also can help treat it more effectively, the researchers say.

News • Variations in patient access

Biliary tract cancer: inequalities across Europe

Research on biliary tract cancer is advancing rapidly, ranging from targeted treatments to new drugs. However, the delivery of these advances to patients is lagging behind, new European studies find.

News • Tissue microstructure analysis

New cancer imaging technique inspired by butterfly wings

The shimmering blue wings of a Morpho butterfly are not just beautiful to look at - they can also help make cancer diagnosis faster, more accurate and more accessible, new research finds.

News • Cell-free tumor DNA analysis

Liquid biopsy to unlock breast cancer treatments

New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.

News • Multi-omics-based prediction

Pancreatic cancer: 'biomarker panel' brings hope for early detection

The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.

News • A closer look at the GI microbiome

“Gut-on-a-chip” predicts immunotherapy efficacy against melanoma

The gastrointestinal microbiome holds valuable information that can help predict whether immunotherapy will be successful against melanoma. A new “gut-on-a-chip” is designed to do exactly that.

News • Hyper-elevated RNAPII detection

New biomarker predicts aggressiveness of brain, breast cancer

Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting the aggressiveness of meningioma brain tumors and breast cancers.

News • Age-related cellular and molecular changes

How aging breast tissue shapes breast cancer risk

Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.

News • Alteration of immune response

Multiple myeloma: dangerous diversity

When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.

News • Micro Immune Response On chip (MIRO)

Replicating tumours to assess cancer immunotherapy efficacy

Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.

News • Research on RAD51 biomarker

Next-generation sequencing for personalizing prostate cancer treatment

Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.

News • Trial results surpass expectations

AI enhances breast cancer screening performance

AI-supported screening for breast cancer can detect more cancer cases compared with traditional screening, and find more invasive cancers at an early stage, results from the MASAI trial indicate.

News • Quantification of serum biomarkers

Early detection of lung cancer with low-cost biosensor

A sensor, similar to glucose monitoring devices, detects lung cancer biomarkers from a blood sample in just 40 minutes. The technology has potential to identify at-risk patients and tailor treatments.

Article • Point-of-care diagnostics

Improving women’s health in remote regions with digital pathology

Point-of-care diagnostics based on a combination of mobile-sized scanners and artificial intelligence (AI) are helping save the lives of women in low-resource settings. The AI technique is being applied in Kenya and Tanzania to deliver screening for cervical cancer – now the leading cause of cancer-related deaths in women in that region and a bigger cause of death than childbirth.

News • Researcher reveals vulnerability

New approach to crack persister tumour cells

Persister cells arise as a result of cancer treatment and are often responsible for tumour relapse. Researchers identified a distinctive feature of persister cells, paving the way for new treatments.

News • Structural research

Researchers use “hallmarks of cancer” to understand tumour growth

“What is a tumour?” Researchers explore tumour architecture as a valuable source of information to understand tumour dynamics and predict its sensitivity to anticancer drugs.

News • Neuro-Oncology

Why late-stage breast cancer patients should receive routine brain MRI screening

Late-stage breast cancer patients are more often affected by brain metastases than previously believed, a new study finds. The researchers suggest that MRI screening guidelines should reflect this.

News • Successful clinical validation

Urine-based test detects aggressive prostate cancer

Researchers have clinically validated a previously developed urine test for prostate cancer screening, which can potentially bypass invasive procedures among men who are unlikely to benefit.

News • Oncological gynecology

Cervical cancer: HPV vaccine to get rid of precancerous lesions

Infection with the human papillomavirus (HPV) is the most common cause for cervical cancers. Now, researchers have developed a promising therapeutic vaccine against precancerous lesions.

News • Molecular mechanism discovered

Researchers find a way to stop harmful cells after cancer treatment

Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.

News • Immuno-monitoring study

New ways for childhood cancer immunotherapies

The immune system of children reacts differently to cancer than that of adults. New insights into these differences have the potential to lead to new tailored treatments for children with cancer.

News • Automated tumor detection and segmentation

Deep learning helps detect lung cancer on CT

A new deep learning model shows promise in detecting and segmenting lung tumors. The findings of the study could have important implications for lung cancer treatment.

News • mpMRI vs TURBT

Bladder cancer: MRI scanning and biopsy as shortcut to correct treatment

Patients with a common aggressive type of bladder cancer could get correct treatment significantly quicker as new research suggests that initial MRI imaging and biopsy could reduce wait times.

News • Machine learning prediction

AI opens non-surgical way to detect brain cancer metastasis

Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients’ cancer without aggressive surgery.

News • Catheter-based approach

New method aims to "steam away" prostate cancer

Steam eliminates wrinkles and germs, but can it destroy cancer cells too? A multisite clinical trial explores the potential of a water vapor system using steam to kill prostate cancer cells.

News • Patient-derived samples

New ‘explant’ technique predicts breast cancer therapy response

A new study measured how well breast cancer patients’ tumour ‘explants’ respond to chemotherapy or HER2 antibody therapy in the laboratory. This could help improve clinical outcomes.

News • Promising prototype

A “diagnostic wand” to detect oral cancer

Liverpool physicists have developed a “diagnostic infrared wand” to more accurately predict the prognosis of oral cancer lesions than current H&E staining techniques.

News • Osteosarcoma research

Driver behind aggressive bone cancer identified

By analysing the largest collection of whole-genome data from osteosarcoma patients, researchers identified a driving mechanism behind the aggressive development of these bone cancer tumours.

News • Early-stage disease stratification

Predicting lung cancer outcomes with tumour DNA in the blood

A new personalised oncology platform has been tested to detect circulating tumour DNA (ctDNA) in patients with lung adenocarcinoma before surgery, to predict their risk of cancer relapse.

News • Long-wavelength exposure

Red light linked to lowered blood clot risk

Light can change biological processes and affect health. For example, new research finds that red light can lower rates of blood clots that can cause heart attacks, lung damage and strokes.

News • Surprising insights

Research explains how tumor cells die after radiotherapy

Why does radiation therapy kill cancer cells from the same tumour in different ways? This has long remained poorly understood. Now, new findings open up opportunities to improve treatment.

News • Research on MRD in tongue cancer

Understanding chemotherapy resistance in oral cancers using organoids

Tongue cancer cells can become resistant to chemotherapy under certain circumstances. Investigating these mechanisms, researchers shed light on promising avenues toward new treatments for this cancer.

News • World first procedure

Testicular tissue transplant provides hope for restoring fertility after chemotherapy

A premiere that brings hope for fertility restoration to men who underwent chemotherapy during childhood: Researchers reintroduced cryopreserved immature testicular tissue taken 16 years prior.

News • Results from the PRAIM study

Mammography screening enhanced by AI

Improved breast cancer detection, reduced workload for radiologists: The world’s largest prospective study on AI in Germany’s Mammography Screening Program reveals the technology's benefits.

News • Checkpoint inhibitor immunotherapy efficacy

AI tool uses routine blood tests to predict cancer immunotherapy response

Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.

News • Pandemic-induced treatment delays

“Heartbreaking”: the impact of Covid on children with brain tumours

Paediatric brain tumours are difficult to diagnose and treat – especially, when delays occur. A new study explored the impact of the Covid-19 pandemic on children with brain tumours.

News • Precision oncology research

Breast cancer chemotherapy receives boost from localised magnetic fields

Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of breast cancer chemotherapy while reducing its harmful side effects.

News • Immunology

Researchers discover new type of anticancer T-cell

A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.

News • Bacterial-induced host metabolic shift

How Salmonella can lead to colon cancer (and how it may be stopped)

Infections with Salmonella can increase the risk of colon cancer. New research sheds light on how this bacterium can cause this. The findings provide new leads for new treatments.

News • Ultrasound-based lesion detection

Ovarian cancer diagnosis improved by AI

Ovarian cancer is common and often only detected by chance. A newly developed AI-based model could help differentiate between benign and malignant ovarian lesions.

News • Driving mechanism identified

Why the lung is a frequent site of cancer metastasis

More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the lungs such a tempting place for cancer cells? New research may have an answer.

Article • Keynote on integrated diagnostics

Predicting – and shaping – the future of modern pathology

Complex diseases could require complex biomarkers for accurate diagnosis in the years ahead, according to a leading pathologist. In a keynote address to the 36th European Congress of Pathology in Florence, Italy, Professor Manuel Salto-Tellez highlighted this as one of the major future challenges for the discipline. However, he also believes pathologists will sit at the core of modern medicine.

News • Rupture prevention

Breast implants: the importance of regular screenings

Women with breast implants should regularly attend follow-up care to avoid the risk of "silent" implant ruptures and their long-term complications, experts caution in a new publication.

News • Research into new therapies

How natural killer cells could fight leukemia more effectively

Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.

News • PET compound

New radiotracer lights up aggressive cancer tumours

A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.

News • DTI reveals intraepithelial neoplasia

Detecting pre-malignant pancreatic lesions with diffusion tensor MRI

In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.

News • Accelerated bone-to-implant integration

Responsive coating could fast-track implant integration after surgery

A new type of photocurrent-responsive coating has been shown to shorten the bone-to-implant integration time after orthopaedic surgery to just two weeks.

News • Field-cycling imaging

FCI: New MRI-derived scanner shows promise for stroke imaging

Using a technique called field-cycling imaging (FCI) derived from MRI, researchers are able to detect signs of brain damage from stroke at ultra-low magnetic fields.

News • Human papillomavirus infection

Cervical cancer: improved screening through HPV risk groups

Analyses of self-tests for human papillomavirus (HPV) can be used to divide HPV-positive women into three risk groups, according to a new study. This could enhance cervical cancer screening.

News • Cancer development research

Exploring the role of sex in tumor growth

Tumors in female fruit flies grow significantly larger than in male ones, a new study finds. The findings could lead to a better understanding of how the biological sex impacts cancer development.

News • Reduction of severe side-effects

A 'kinder' chemotherapy for Hodgkin lymphoma

Treating patients with Hodgkin lymphoma with a different form of chemotherapy shows promise to reduce severe side effects, shorten hospital time and increase likelihood of recovering fertility.

News • New approach to combat treatment resistance

How chemotherapy affects ovarian cancer tumours

Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.

News • Advances in precision medicine

MASLD: Research reveals two types of fatty liver disease

Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.

News • Striking structural reorganisation

Pregnancy and nursing massively changes up mothers' intestines

When women are pregnant and nurse their babies, their bodies change to ensure the health of both mother and child. Researchers now surprisingly find that the intestine also changes completely.

News • Inhibition of Sars-CoV-2 proliferation

New 'hairpin' tool stops coronavirus in its tracks

A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.

News • Hyperpolarised carbon-13 imaging

Metabolic MRI imaging distinguishes ovarian cancer subtypes

A new MRI-based imaging technique predicts the response of ovarian cancer tumours to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.

Article • AI-assisted image analysis

More accuracy in brain tumour segmentation

Precise segmentation of anatomical structures greatly benefits cancer diagnosis. Using AI and deep learning methods, researchers are developing a high-precision 3D viewer software for medical image data.

News • R&D platform

Integrating AI into clinical workflows for medical imaging

To advance the transition of AI from research to clinical application, Nvidia announced that Siemens Healthineers has adopted MONAI, an open-source medical imaging framework.

Article • Artificial intelligence meets internal medicine

Medical AI: Enter ‘dea ex machina’

In the world of theatre, the ‘deus ex machina’, the god from the machine, is a dramaturgical trick to resolve seemingly unsolvable conflicts. Can artificial intelligence (AI) also be such a universal problem solver for internal medicine? At the Annual Congress of the German Society of Internal Medicine (DGIM), Dr Isabella Wiest explored the potential – and limitations – of AI helpers.

News • Coronary artery disease detection

Low-dose chest CT may detect more than just lung cancer

As new research shows, low-dose chest computed tomography (CT) can identify coronary artery calcium, a strong risk factor for coronary artery disease (CAD), in patients without cardiac symptoms.

News • From the brain to the abdomen

Stroke might affect arteries in other body regions

New research has linked having a cerebral stroke to lasting changes in the arteries in the abdomen. The study in animal models with hypertension could lead to new preventative strategies.

News • Deep learning advances

New AI model for cell segmentation and classification

US researchers have developed a comprehensive deep learning AI model designed to more accurately identify and classify cells in high-content tissue images.

News • Solving the key constraints of PET substrates

Safer radiotherapy with wearable organic x-ray sensors

A research team has found wearable organic x-ray sensors could be the answer towards safer radiotherapy protocols for cancer patients, reducing the debilitating side-effects of the treatment.

News • Tumour movement across tissues

Understanding metastasis: migration strategies of ovarian cancer

A new study shows how inherent variations in a cancer cell and its interactions with its surroundings mould its migration. The findings provide valuable insights into the processes behind metastasis.

News • Dermatology

Exploring fibroblast subtypes and skin cancer aggressiveness

New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.

News • New insights on aneuploid epithelial cells

Breast cancer-like cells also found in healthy women

A certain type of cells, called aneuploid epithelial cells, are usually associated with breast cancer. However, new research reveals that they can also be found in healthy women.

News • Insights on bias avoidance

New breast imaging technique to improve visibility across skin tones

A new imaging technique reduces skin tone bias in breast cancer detection, improving visibility across diverse skin tones.

News • New therapy approach for brain tumors

Attacking glioblastoma from multiple angles

A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.

News • Interstital lung disease

Lung cancer: PET/CT imaging analysis with AI predicts immunotherapy side effects

PET/CT image analysis using artificial intelligence (AI) can predict the occurrence of interstitial lung disease, a serious side effect of immunotherapy in lung cancer, a new study shows.

News • Incidentaloma detection

Liquid biopsy as diagnostic tool for pancreatic lesions

New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.

Article • Between good practice and financial pitfalls

Delivering molecular pathology at lower costs

Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.

News • Do no harm

“Never words” in doctor-patient communication (and what to say instead)

“There’s nothing else we can do”, “Why did you wait so long to come?” – doctors should avoid using such phrases. A new study points out the destructive potential of “never words”.

News • Tradefair programme overview

Don't miss: Hot issues, current trends and innovations at the Medica 2024 Labmed Forum

Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.

News • Research on new sensing mechanism

Finding signs of lung cancer in exhaled breath

Researchers from China have developed ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer.

AI making earlier detection of colorectal cancer possible

Early detection is crucial for effective treatment of colorectal cancer, but the initial stages are easily missed during endoscopy screenings. With GI Genius, Medtronic presents an AI-powered tool to help detect precancerous lesions in real-time. In an upcoming large-scale trial, the intelligent endoscopy module will demonstrate its benefit in the clinical context.

News • Microgravity-induced changes

How cancer cell cultures in space can help defeat cancer on Earth

New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.

News • Insights into tumor biology

Breast cancer: Exploring metastasis diversity

In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.

News • Research on "double strike" mechanism

Induction of defective cell division could improve blood cancer therapy

Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.

News • Photothermal disinfection

Frying bacteria on implants with tiny gold radiators

New technology shows promise in protecting an implant against infections from resistant bacteria: By heating up small nanorods of gold with near-infrared light (NIR), the bacteria are killed.

News • Catch some EVs

Liquid biopsy to improve cancer diagnosis

A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.

News • Insights into bile production

Liver discovery could lead to better CVD treatments

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.

News • Radiopharmaceutical study

New mini-protein shows promise in targeted radiation delivery to tumors

A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.

Celebrating molecular imaging milestones across Europe

United Imaging launches the uMI Panvivo, the uMI Panorama GS and Nuclear Medicine AI Solution at EANM, and announces strategic partnerships, reinforcing its commitment to advancing molecular imaging in Europe and beyond.

Video • Cancer research

3D-printed tumor model reveals metastasis mechanisms

New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.

Taipei showcases cutting-edge medical devices & diagnostics at Medica 2024

Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.

Interview • Congress showcases advances

Making immunotherapy work for more cancer patients

Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.

News • PFAS and Kidney Health

New research reveals connection between PFAS, kidney function and gut health

New research has revealed that the connection between PFAS, and kidney damage may be tied to dysregulation of the gut microbiome.

News • Hibernation

Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold

A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.

News • Cancer treatment advances

USC study findings: early blood test forecasts survival rates in patients with metastatic prostate cancer

A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.

News • DNA damage response

New insights into the DNA damage response

The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.

Interview • AI, modern mammography, and more

Breast imaging breakthroughs presented at EUSOBI 2024

Minimally invasive surgical interventions, innovative imaging and the use of AI: At the upcoming EUSOBI congress in Lisbon, experts present and discuss the latest advances in breast imaging. We spoke with Tanja Brycker from Hologic ahead of the event about new trends in women’s health, the company’s investment in innovation and education, and what the future of mammography looks like with the…

News • Miniature instrument transport

Robotic "convoy" advances endoscopic surgery

Miniature robots often lack the strength to transport instruments for endoscopic microsurgery. But what if they worked together? Scientists have pursued this idea to perform a surgical procedure.

News • Discussion on nomenclature

“Prostate cancer” or “incidentaloma”: What should early findings be called?

Certain early-stage changes to the prostate very rarely develop into aggressive cancer, but are still called that. Would it create a false sense of security to not call these “cancer” at all?

News • BAC as predictor of cardiovascular disease

Mammograms can detect more than breast cancer, study finds

Measuring the calcium build up in the arteries of the breast, researchers have developed an AI-generated score for predicting cardiovascular disease in women from their mammograms.

News • Single-cell metabolic profiling

Mass-spec and IMC give deep insights into tumors

By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.

News • Brain cancer immunotherapy

Turning immune cells against glioblastomas

Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.

News • Experts propose combination strategy

Kidney cancer: early detection through 'piggyback' screening

Kidney cancer is relatively rare, so dedicated screening programmes would not be cost-effective. Combined with lung cancer screening, however, this would be much more feasible, a new study shows.

News • Hematology

Using AI to predict multiple myeloma evolution

Researchers have succeeded in identifying patterns of response to treatment in patients with multiple myeloma using AI tools, which helps to accurately predict the evolution of the tumor.

News • Hard to treat cancers

KRAS “degrader” could lead to treatment for millions of cancer patients

A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.

News • Transport of minuscule gold particles

Nanoparticles could detect kidney disease better than blood tests

Before administering certain drugs, doctors check a patient’s kidney function by testing their blood urea nitrogen and creatinine levels. New research shows that gold nanoparticles might give more accurate results.

News • Individualized therapy planning

Tumour irradiation: a little different every day

A bit more mucus in the nose, a little less air in the gut: Even small changes can be important when planning proton therapy against cancer. A new workflow allows for an adapted irradiation every day.

News • Groundwork for new treatments

Fibrosis a prognostic biomarker for HER2-negative breast cancer

A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.

News • Breast cancer detection

Decade of DBT: 10-year study shows benefits of tomosynthesis

Evidence of the superiority of tomosynthesis for breast cancer detection is stacking up, with new results from a 10-year study further demonstrating the 3D imaging technique's benefits.

News • Strengthening the immune defense

STAb-T: new immunotherapy method shows promise against lung cancer

STAb-T, a new form of immunotherapy to treat solid tumours shows therapeutic potential in animal models with non-small cell lung cancer. The new strategy is designed to strengthen the defensive cells.

News • AnWj blood group antigen

MAL: new blood group system discovered

Researchers identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of patients lacking this blood group.

News • When red means bad (for the heart)

Nutri-Score hints at foods that increase CVD risk

The Nutri-Score is designed to provide consumers with information on nutritional quality. New research reveals that the ratings also correspond with the cardiovascular health impact of the products.

News • Checkpoint inhibitor research

Five key factors predict response to cancer immunotherapy

Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.

News • Multimodal analysis

Immunotherapy: tumour microenvironment holds clues to treatment success

Currently, it is difficult to predict whether a cancer patient will respond to immunotherapy or not. A new method to quantify the heterogeneity of the tumour microenvironment aims to improve this.

News • Research on BRCA recurrence

Breastfeeding after breast cancer treatment is safe, studies find

Two international studies presented at the ESMO Congress 2024 show no increase in recurrence or new breast cancers in women who breastfeed after being treated for breast cancer.

News • Glioblastoma research

Brain scars from cancer treatment key factor for relapse

Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.

News • Dynamic network analysis

AI unlocks new path to personalized cancer treatments

A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.

News • Reducing chemotherapy side effects

Trapping cancer cells in molecular 'cages'

Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.

News • COPD and asthma

Certain lung conditions could "mask" lung cancer, delay diagnosis

Certain long-term health conditions such as chronic obstructive pulmonary disease (COPD) and asthma, can obscure early symptoms of lung cancer, leading to delays in diagnosis, a new study finds.

News • Quicker, cheaper and less painful test

Blood crystals to reveal early signs of prostate cancer

A new method of analysing the crystals in dehydrated blood could lead to a quicker, cheaper and less painful technique to diagnose, early detect, and monitor prostate cancer.

News • Breast cancer screening

The emotional impact of false positive mammograms

Mammography can lead to “false positives,” meaning they do not result in a breast cancer diagnosis. This may discourage some women from future screenings, according to a new study.

News • Towards personalised risk assessment

Training an AI to early detect dementia with big data

With enough medical training data, AI can predict health conditions with astounding accuracy. Now, researchers want to use brain scans of the entire Scottish population to have an algorithm early detect dementia.

News • High-resolution cell scans

AI spots cancer and viral infections at nanoscale precision

Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.

News • Remote procedure from Hongkong to Zurich

Telemedicine: endoscopic surgery across 9300 km

Breakthrough for telemedicine: Surpassing a distance of 9,300 kilometers, surgeons from Hongkong and Zurich successfully performed an endoscopic procedure in an animal model.

News • Circadian-based therapeutic strategies

Cancer drugs more effective when the time-of-day is right, study finds

The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.

News • Automated tissue analysis

Digital pathology: AI platform to improve lung cancer diagnosis

Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.

News • Neuroblastoma diagnosis without anaesthesia

New PET/CT technique improves brain tumour detection in children

To diagnose neuroblastoma in children, lengthy scans and anaesthesia are often required. A new PET/CT imaging technique could deliver faster results without sedation for the paediatric patients.

News • Antibiotic resistance control

Better tracking of AMR hospital bacteria

Infections caused by antibiotic-resistant (AMR) bacteria are a major issue in hospitals. A new technique aims to effectively track all types of relevant microorganisms simultaneously.

News • Time loss vs. life expectancy gains

Dialysis: Is the tradeoff always worth it?

New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.

News • COLO-DETECT trial

Bowel cancer: AI improves early detection

Artificial intelligence (AI) can be used to great effect in colonoscopies to spot abnormalities potentially leading to bowel cancer. This is the result of the recently completed COLO-DETECT trial.

News • Promising research on oral rinse-based test

Wash, rinse – detect head and neck cancer?

Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.

News • Combined chemo and radiotherapy

Promising treatment for rectal cancer to avoid surgery

When a person is diagnosed with rectal cancer, part of the bowel is often removed, often resulting in the need for a stoma or problems with bowel control. A new therapy could help avoid this surgery.

News • Glycopeptide probes for antibody detection

New method speeds up pancreatic cancer detection

A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.

News • Prevention of surgery complication

Sterilization: cut or remove fallopian tubes?

Women whose Fallopian tubes are removed during sterilization have only marginally more surgical complications than those whose tubes are simply cut, a study shows.

Article • AI is key

Lung cancer screening initiatives across Europe

Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.

News • Recurrence timeframe analysis

Breast cancer radiotherapy: new insights on duration of protective effect

After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.

News • Genome and transcriptome analysis

Colorectal cancer prognosis derived from genetic signatures

Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.

News • Non-invasive risk assessment

Prostate cancer: avoiding unnecessary biopsies with AI

Combining risk markers, systematic evaluation of MRI images and AI, researchers aim to predict the risk of prostate cancer more accurately than before. This could save many patients from a biopsy.

News • Image analysis

Deep learning model detects prostate cancer on MRI scans

The interpretation of prostate MRI is notoriously difficult. Annotating AI shows promise to help improve diagnostic performance through increased cancer detection rates with fewer false positives.

News • Macrocyclic hybrid probe

New dual PET/MRI contrast agent to enhance kidney diagnostics

A new type of contrast agent for use in both MRI and PET imaging has the potential to significantly enhance diagnosis and subsequent treatment, particularly for kidney diseases and tumors.

News • Promising study results

Cancer of Unknown Primary: on the way to targeted therapies

Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.

News • Basal cell carcinoma diagnostics

BCC: AI helps identify aggressive types

Dermatologists could benefit from a new algorithm that can help recognize patients with a highly aggressive form of basal cell carcinoma (BCC) of the face.

News • Brain cancer research

Glioblastoma: Surprising find of immune cells

Researchers discovered islands of highly potent immune cells in the vicinity of glioblastomas. This may open up prospects for new therapies for these aggressive brain tumours.

News • Lower dose, improve tolerability, retain efficacy

Prostate cancer therapy: benefits of therapy deescalation

Radiotherapy of prostate cancer often comes with side effects, causing some patients to discontinue treatment. New research shows the benefits of at lowering the dose over subsequent treatment cycles.

News • Tumor assessment via chromatin imaging

From DCIS to IDC: AI identifies breast cancer stages

Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.

News • Concerns about hurried adoption

Survey: Is medical AI taking over too quickly?

The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.

Opinion article • Wearable medical devices

Sweat analysis reveals a wealth of health information

Diagnosis and monitoring medical conditions, including cancer, diabetes, heart disease, and infections: In this opinion article, Alix Joseph (Linxens) explores the potential of sweat analysis.

News • Hydrogel solution

Breakthrough in fridge-free storage of medicines

Many medicines require cold storage, which is a challenge for infrastructure and sustainability. Now, researchers designed a hydrogel protecting therapeutics at temperatures as high as 50°C.

News • Focus on ferroptosis

Major step towards a treatment for metastasis

Researchers have discovered an Achilles heel of migratory metastatic cells: They now investigate how the cell death mechanism ferroptosis can be utilized for future cancer treatments.

News • Immunology

“One and done”: promise for a universal influenza vaccine

New research reveals a promising approach to developing a universal influenza vaccine that confers lifetime immunity against an evolving virus considered most likely to trigger the next pandemic.

News • Public survey on medical conditions

Cancer seen as #1 health concern, AI as solution

Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.

News • Electronic prompt in the EHR

‘Nudging’ surgeons away from breast cancer overtreatment

Sentinel lymph node biopsies can help detect breast cancer – but not every patient benefits from the procedure. New research finds that a simple EHR prompt can prevent unnecessary surgery.

Article • Delivering more efficient healthcare

How teleoperation is changing radiology

As opportunities for teleoperations rapidly expand within radiology, the concept is being deployed across an array of modalities to deliver more efficient healthcare. A range of speakers covered the topic of ‘Teleoperations in radiology’ at ECR2024, discussing its benefits in applications in MRI, ultrasound, during the social restrictions of the Covid-19 pandemic and military use. However,…

News • Diffuse Large B-Cell Lymphoma (DLBCL)

Personalised simulations predict outcomes for blood cancer treatment

Using genomic sequencing data, researchers have created personalised simulations of individual patients that can quantify the impact of genetic mutations on cancer cell behaviour.

News • Tailored chatbot

Customized ChatGPT to advance digital pathology

New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.

News • Tumour infiltrating lymphocyte measurement

Breast cancer: AI tool predicts which DCIS cases become invasive

Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.

News • Taxane-induced peripheral neuropathy

New tool predicts nerve damage after breast cancer chemotherapy

Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.

News • Focus on microproteins

Researchers find potential target for liver cancer vaccine

Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.

News • HPV oncoprotein quantification

Urine test improves cervical cancer early detection

A new test shows promise in making cervical cancer screening more accessible and less invasive by detecting oncoproteins of the human papillomavirus (HPV) in urine samples.

News • Circulating tumor extracellular vesicles

Metastatic prostate cancer: better monitoring with new liquid biopsy method

A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.

Article • Institutional setup guide at SNMMI 2024

How to establish a hospital theranostics treatment centre

The nuclear medicine global market is projected to see a significant increase in the coming years, with the lion's share being attributed to radiotherapeutics. So, how to set up a dedicated theranostics centre? At the annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Toronto, Ontario, an entire session was dedicated to planning logistics, radiation safety, and…

News • Adaptive mutability

How bowel cancer flips the switch to avoid immune detection

Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.

News • Research on physical conditions

Exploring the link between obesity and cancer risk

Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.

News • The role of tissue stiffness

Pancreatic cancer: new approach could reverse chemo resistance

Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.

News • Diabetes, hypertension, and more

AI reads facial temperature for early diagnosis of metabolic diseases

Measuring temperatures in different face regions could be used to earlier detect chronic illnesses, such as diabetes and hypertension. Researchers now show the potential of an AI-based approach.

Article • Compared to laparoscopy

Robotic surgery improves colorectal surgery outcomes

When colorectal surgery was first performed with robotic assistance in 2014, the procedure was questioned about safety, efficacy, and outcomes. Today it is an established option. Well-trained surgeons use robotic surgical systems confidently. Numerous clinical studies have verified its intraoperative benefits for patients and surgeons alike, as well as very positive outcomes for patients.

Brand-new nuclear medicine department equipped with advanced Total-Body PET/CT system

The new Nuclear Medicine Department of the San Pietro Fatebenefratelli Hospital was inaugurated in Rome. The Department was inaugurated with the online intervention of Health Minister Orazio Schillaci and in the presence of Maria Tripodi (Undersecretary at the Ministry of Foreign Affairs and International Cooperation), Antonello Aurigemma (President of Lazio Regional Council).

News • New insights on shape and toxicity

Small, but mighty – how gold nanoparticles (actually) kill cancer

Smaller kills faster – this is what was previously thought about gold nanoparticles used to fight cancer cells. However, new research reveals a more complex picture of these interactions.

News • "Candycrunch"

AI and mass spectrometry to find cancer clues at lightning speed

Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.

News • Vital mechanism discovered

Promising approach to prevent breast cancer recurrence

Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.

Article • Professional perspectives

Theranostics: A career opportunity for Nuclear Medicine Technologists

What is an advanced clinical practitioner (ACP) and why should nuclear medicine technologists strive to become one? At the 2024 annual meeting of the SNMMI in Toronto, ACP Luisa Roldão Pereira outlined the position and its importance in the clinical context.

News • Digital support

New app triples chance to quit smoking

Finnish researchers found that using a mobile application based on cognitive behavioral therapy can significantly boost success rates of people attempting to stop smoking.

Article • Addressing diagnostic backlogs

Harnessing the power of AI for women's health

Although the Covid-19 pandemic is behind us, healthcare facilities continue to experience workflow challenges and resource constraints impacting women’s health and a patient’s ability to receive a timely diagnosis. Clinical specialties like breast radiology and cytology are especially susceptible to these issues and continue to experience backlogs, which impact their ability to deliver timely…

News • Iontronic technology

Slowly but steady gets the brain tumour

Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.

Article • Challenges and opportunities

Molecular pathology in Europe: in search of standardization

Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.

Article • Benefits of seated placement

Patient positioning during cancer radiotherapy: Upright is alright

The concept of delivering radiation therapy to cancer patients seated in an upright position is undergoing a major resurgence. Evidence is already highlighting that patients feel more comfortable seated upright and enjoy better communication with radiotherapists during their care. In addition, there are indications of less internal organ movement, enabling more accurate treatment delivery.…

News • Reduction of greenhouse gas emissions

Telemedicine for more sustainable cancer care

Cancer care that utilizes telehealth and local care would generate 33.1% less greenhouse gas emissions than the traditional model, new research finds.

World's First Total-Body PET/CT with 194 cm Axial FOV installed in Europe

The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.

News • Impact on mammography performance

Breast cancer screening: better detection, fewer false positives with AI

Using artificial intelligence (AI), breast radiologists in Denmark have improved breast cancer screening performance and reduced the rate of false-positive findings.

News • Antibacterial protein as therapeutic target

Pancreatic cancer: new approach for immunotherapy

Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.

Innovative Avenue of Treatment – Internal Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer

In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.

News • Foetal development research

Tracing back the origins of AML childhood leukaemia

Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.

News • Neuropathology

Technology offers new insights into pediatric brain tumors

A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

News • Integration of microanalysis chips

Establishing microfluidic control technology for blood testing devices

A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.

News • Success of aRCC treatment

New biomarker to better predict immunotherapy response in kidney cancer

Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.

News • Insights into ink

Study links tattoos with increased lymphoma risk

A new study suggests that tattoos could be a risk factor for cancer in the lymphatic system, or lymphoma. Now, the researchers underline the need for more research on the topic.

Article • Pros and cons of diagnostic techniques

Liquid biopsy vs. tissue biopsy: Getting the best of both worlds

Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.

News • Stratification approach

Using national health data to predict cancer risk

Scientists show that health registry data can be used to predict individual risks for the 20 most common cancer types. This could help to identify high-risk groups and enrol them for screenings.

News • UK study confirms

Lung cancer screenings: benefits across all socioeconomic groups

Lung cancer screenings save lives – especially for those who live in economically deprived areas, a new study confirms. The researchers further demonstrate the benefits of using low-dose CT imaging.

News • Impact of patient characteristics

Breast cancer AI: unequal performance across ethnicities and age groups

Current AI systems for detecting breast cancer from mammography exams are more likely to produce false-positive results in black women and older patients, a new study finds.

News • CT-Derived Functional Imaging

CTFI: Enabling CT lung diagnosis without contrast

Diagnosing lung conditions such as pulmonary embolism is more challengenging when a patient cannot tolerate contrast agents. Now, a new software solution is addressing the issue.

News • Hydrogel catalyst

Breaking down alcohol in the body: Researchers develop "detox gel"

Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.

News • Research on DNA danage

Surprise finding on cancer cell death to impact therapies

Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.

Article • Advancements in endoscopy

Enhancing diagnosis and disease monitoring for ulcerative colitis

Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.

News • Clear cell renal cell cancer

Same-day imaging for ccRCC kidney cancer with new PET agent

A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).

News • Three-dimensional tissue processing

Pathology performs leap into 3D with AI

Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.

News • 6.5 million European funding

Fighting cancer with artificial cells and tissue

Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.

News • Leukemia MRD after chemo

AML: Residual cancer testing as an important safeguard

Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.

News • On-demand reversibility

Anticoagulation with an ‘on/off’ switch

Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.

News • Opportunity for new treatment approaches

Atherosclerosis and cancer share surprising similarities, study finds

In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.

News • Ciliopathy reseach

Rare lung disease: genetics reveals cause of PCD

Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.

News • MRSA and other infections

Researchers develop vaccine to fight antibiotic resistance

Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.

News • Urine-based diagnostics

New prostate cancer test to help avoid unnecessary biopsies

US researchers have developed and validated a new urine-based test for prostate cancer, which was shown to meaningfully reduce unnecessary prostate biopsies while providing highly accurate detection.

News • Research on large foundation models

Reducing bias in pathology AI

A study highlights performance differences in computational pathology systems, depending on demographic profiles associated with histology images. The researchers also propose a way to fix this bias.

News • Nuclear medicine

Prostate cancer: New SPECT/CT technique for greater treatment precision

A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.

News • GMAI for cancer treatment

Generalist Medical AI: Experts propose legal guardrails

Generalist Medical Artificial Intelligence (GMAI) models pose a significant challenge to current regulatory frameworks. Experts discuss how regulation of these models could work in the future.

News • Novel probe assesses cell stiffness

A 3D endo-microscope for early cancer diagnosis

Stiffness in tissues can be a valuable indicator of cancer formation. Now, researchers have developed a microscopic probe to perform histology at the single cell level inside the human body.

News • Atypical teratoid/rhabdoid tumours

Understanding the development of AT/RT brain cancer in children

Unlike most tumours, atypical teratoid/rhabdoid (AT/RT) tumours develop very quickly. Now, researchers explored the mechanisms of these aggressive brain tumours that mainly affect young children.

News • Voice box cancer treatment

Laryngeal cancer: AI software to better predict outcomes

Experts at Newcastle University have discovered artificial intelligence can be used to analyse medical imaging from CT scans, which is aimed at predicting survival in patients with laryngeal cancer.

News • Research on biomechanics

Tumour 'softness' can drive aggressiveness of breast cancer

Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.

Article • Lesion detection and mammographic texture analysis

Dual AI model to optimize breast cancer risk assessment

A team of Danish and Dutch researchers has combined an AI diagnostic tool with a mammographic texture model to improve the assessment of short- and long-term breast cancer risk. This new approach represents a significant step forward in refining the ability to predict the complexities of breast cancer risk.

News • Mechanistic subtypes

The telltale traces long Covid leaves in the blood

Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.

Article • Pharmaceutical research

Boosting biomarker detection with digital pathology

Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.

News • Microbial influence on treatment

Study explores the role of bacteria in cancer

Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.

News • Promising secretory granules

New micromaterial to fight cancer with nanoparticle-targeting

A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.