Researchers used state-of-the-art 3D bioprinting to replicate the complex structure and environment of spinal discs. Their insights hold promise for understanding back pain and disc degeneration.
Results of a new retrospective study demonstrate the potential of a novel, CT-based deep learning-driven tool to enhance liver cancer diagnosis, treatment planning, and response evaluation.
At the San Antonio Breast Cancer Symposium (SABCS), three experts presented new approaches and study results for the treatment of breast cancer in young women.
A new biomarker for multiple sclerosis: the inflammatory cell rim from microglial cells surrounding brain lesions was found to directly correlate with the severity and speed of disease progression.
From organ-preserving treatments to chemo-immunotherapy combinations: five studies presented at ESTRO 2025 showcase how radiotherapy is reshaping the treatment landscape for anal and rectal cancer.
Pupil dilation and involuntary facial movements could provide a window into diagnosing tinnitus. A new method uses AI to detect minuscule reactions to various sounds and noises.
A new approach enables the detection of even trace amounts of cancer cells. The method leverages SERS for signal amplification, eliminating the need for fluorescent dyes.
Bringing diagnostics and therapy closer together - that is the basic concept behind theranostics. Through further development of its PET/MR scanners, Siemens Healthineers aims to advance this approach. Andreas Schneck, Head of the MRI Division at Siemens Healthineers, talks about the new system, which was also presented at the European Congress of Radiology (ECR) in Vienna, and its advantages in…
Unprecedented insights into the inner workings of an early-stage lung tumor: An international research team describes a new method for 3D mapping cellular interactions in the tumor microenvironment.
Radiation therapy is an effective component of many cancer treatments, but some patients experience severe side effects. A new study shows that hyperbaric oxygen therapy can provide long-term relief.
Breast MRI has emerged as a powerful diagnostic tool, particularly for women with dense breast tissue where traditional mammography faces limitations. In her presentation at ECR 2025, radiographer Hanna Kalliomäki highlighted several technological advances transforming breast cancer detection and diagnosis. From time-saving abbreviated protocols and AI-assisted analysis to contrast-free…
Arginine vasopressin deficiency (AVP-D) is a rare condition affecting the body's water management. However, it is also known under a different name – this can lead to fatal mix-ups.
A risky carotid artery operation may no longer be necessary for patients who suffer a stroke due to carotid artery narrowing, research suggests. Instead, medication-only treatment may also be viable.
Nuclear medicine (NM), one of the more mature technologies of diagnostic imaging, has been experiencing a rebirth in innovation and interest. The increasing prevalence of cancer, in part the result of improved diagnostic tests, an aging global population, and greater longevity, has created a robust demand for nuclear medicine. At the European Congress of Radiology (ECR) in Vienna, presenters…
Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.
Researchers have succeeded in mapping how blood vessels in the brain react after a stroke. This new insight can lead to more effective treatment and fewer complications for patients.
RNA researcher Anastasia Khvorova, PhD, professor of RNA therapeutics at UMass Chan Medical School, will receive this year's Else Kröner Fresenius Prize for Medical Research on May 15, 2025. The award ceremony will be a part of the festive event together with the Fresenius SE & Co. KGaA celebrating the 100th birthday of Else Kröner, at the Städel Museum in Frankfurt am Main.
Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant chemotherapy and standard radiotherapy, new research finds.
New research has revealed how Duchenne muscular dystrophy (DMD) also profoundly affects the brain, leading to cognitive and behavioural challenges that are very diverse and some could be reversible.
Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.
3 out of 10: Mammography screening has been shown to be effective in reducing breast cancer mortality. Still, many cancers are diagnosed between screening rounds, a new study shows.
The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.
Leveraging bioink from pancreatic tissue and 3D bioprinting, researchers developed a structure closely mimicking the structure of a pancreas, in which cultured cells can resume insulin production.
A new rapid diagnostic test can identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This could help prevent mother-to-child transmission during childbirth.
Using ‘parallel transmit’ technique, researchers have found a new way to detect lesions in the brain of patients with treatment-resistant epilepsy in an MRI scan, without imaging signal dropouts.
Transmission of tuberculosis (TB) in the European Region is still ongoing, and immediate public health measures are needed to control and reduce the growing burden of the disease, experts urge.
World TB Day raises awareness about tuberculosis and commemorates the discovery of the source bacterium M. tuberculosis. More than a century later, scientists still refine anti-TB strategies.
Nuclear medicine specialists have successfully used the radiopharmaceutical Ga-68-Trivehexin from Trimt to accurately diagnose patients with pulmonary fibrosis and concurrent lung cancer.
Cryoablation, the destruction of malignant cancer cells by freezing them, is increasingly becoming an alternative to having conventional lumpectomy for patients diagnosed with early-stage, localised, low-risk breast cancer. Findings from numerous recent clinical trials show that cancer recurrence rates are very low and are comparable to breast conservation surgery (BCS).
For Esaote, a leading Italian innovator in medical imaging - ultrasound, dedicated magnetic resonance and medical IT - the mission is to develop new technologies that can help advance diagnosis and improve patient care. Esaote has always leveraged continuous innovation as the key driver of its business strategy. This approach is also embodied in its three business areas.
A novel sensor placed on a patient’s head registers nanometric expansions of the skull in each cardiac cycle in real time to measure intracranial pressure more accurately and non-invasively.
A new system that seamlessly integrates an implanted spinal cord neuroprosthesis with rehabilitation robotics delivers well-timed electrical pulses to enhance mobility and foster long-term recovery.
Japanese researchers have developed magnetic nanoparticles that can be directed to tumors using a magnet and then heated with a laser to destroy cancer cells while sparing healthy tissue.
The boom in interventional radiology procedures has enabled great strides in ischemic stroke management. But while a myriad of techniques are available, the challenge remains in choosing the most appropriate thrombectomy treatment on the spot, according to Jordi Blasco Andaluz, a neuroradiologist at Hospital Clinic Barcelona. The new ROSSETTI registry is designed to change this.
By detecting nerve connections in the injured spinal cord, a newly developed radiotracer could help diagnose injuries more precisely, monitor recovery, and evaluate therapy effectiveness.
Research on biliary tract cancer is advancing rapidly, ranging from targeted treatments to new drugs. However, the delivery of these advances to patients is lagging behind, new European studies find.
New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.
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The gastrointestinal microbiome holds valuable information that can help predict whether immunotherapy will be successful against melanoma. A new “gut-on-a-chip” is designed to do exactly that.
The Diagnostica e Terapia Centro Aktis in Marano di Napoli, Italy, has expanded its diagnostic department with the addition of three imaging systems from United Imaging.
Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.
When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.
To improve breathing monitoring during radiotherapy, researchers have developed a millimeter-wave sensor capable of non-invasively visualizing respiratory movement during X-ray and CT examinations.
Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.
While thrombectomy to remove blood clots after a stroke is increasingly performed, new research suggests that it may not be needed in all cases.
New AI-enabled systems, intelligent software, and imaging cloud services for improved radiology workflows: Royal Philips announces its solutions that will be showcased at ECR 2025 in Vienna.
Mobile stroke units can greatly reduce time-to-treatment. At this year's International Stroke Conference, Siemens Healthineers is showcasing its new mobile solution to support stroke diagnosis.
Persister cells arise as a result of cancer treatment and are often responsible for tumour relapse. Researchers identified a distinctive feature of persister cells, paving the way for new treatments.
Two recent studies find that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.
“What is a tumour?” Researchers explore tumour architecture as a valuable source of information to understand tumour dynamics and predict its sensitivity to anticancer drugs.
Late-stage breast cancer patients are more often affected by brain metastases than previously believed, a new study finds. The researchers suggest that MRI screening guidelines should reflect this.
Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.
The immune system of children reacts differently to cancer than that of adults. New insights into these differences have the potential to lead to new tailored treatments for children with cancer.
A new deep learning model shows promise in detecting and segmenting lung tumors. The findings of the study could have important implications for lung cancer treatment.
Steam eliminates wrinkles and germs, but can it destroy cancer cells too? A multisite clinical trial explores the potential of a water vapor system using steam to kill prostate cancer cells.
A new study measured how well breast cancer patients’ tumour ‘explants’ respond to chemotherapy or HER2 antibody therapy in the laboratory. This could help improve clinical outcomes.
By analysing the largest collection of whole-genome data from osteosarcoma patients, researchers identified a driving mechanism behind the aggressive development of these bone cancer tumours.
A new personalised oncology platform has been tested to detect circulating tumour DNA (ctDNA) in patients with lung adenocarcinoma before surgery, to predict their risk of cancer relapse.
Light can change biological processes and affect health. For example, new research finds that red light can lower rates of blood clots that can cause heart attacks, lung damage and strokes.
Why does radiation therapy kill cancer cells from the same tumour in different ways? This has long remained poorly understood. Now, new findings open up opportunities to improve treatment.
A premiere that brings hope for fertility restoration to men who underwent chemotherapy during childhood: Researchers reintroduced cryopreserved immature testicular tissue taken 16 years prior.
New insights on the degradation of implantable chips in the body could lead to enhanced longevity of the chips and better treatments for patients with Parkinson's or clinical depression.
Acoustofluidics company Aenitis Technologies has entered a Memorandum of Understanding (MOU) with pharmaceutical company Bracco Imaging to develop next-generation acoustic microspheres.
Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.
Paediatric brain tumours are difficult to diagnose and treat – especially, when delays occur. A new study explored the impact of the Covid-19 pandemic on children with brain tumours.
Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of breast cancer chemotherapy while reducing its harmful side effects.
Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.
A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.
In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.
Social deprivation, infectious diseases, broken bones, and even poison apples: The life of Disney princesses is fraught with hidden health risks, a new study reveals.
Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
Spinal cord stimulation is performed for patients with chronic pain. However, for some patients, the procedure is not effective. A new method involving fMRI could help predict success.
Precise segmentation of anatomical structures greatly benefits cancer diagnosis. Using AI and deep learning methods, researchers are developing a high-precision 3D viewer software for medical image data.
Opposing views on new implantable cardiac devices were aired in a Great Debate session at the European Society of Cardiology’s annual 2024 congress in London. Experts discussed emerging techniques and technologies and debated whether they are actually ready for clinical application. At the core of the session was the issue of whether conduction system pacing (CSP) should replace cardiac…
A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.
US researchers have developed a comprehensive deep learning AI model designed to more accurately identify and classify cells in high-content tissue images.
The current rise in antibiotic resistance is once again sparking interest in phage therapy. Now, scientists developed a new tool that recommends the best possible phage cocktail for a given patient.
A wearable electrical nerve stimulation (TENS) device, which uses low-voltage electrical currents, could help reduce pain, fatigue, and mobility issues associated with long-Covid, a new study finds.
A research team has found wearable organic x-ray sensors could be the answer towards safer radiotherapy protocols for cancer patients, reducing the debilitating side-effects of the treatment.
New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.
Mindray, one of the world's leading developers and providers of advanced medical imaging devices and solutions, launched Resona A20, a premium ultrasound system, at EUROSON 2024 in Naples, Italy.
A newly developed ‘biocooperative’ material based on blood can guide key processes taking place during the natural healing of tissues to create living materials that enhance tissue regeneration.
A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.
Royal Philips announced a major advance in radiation oncology with 510(k) clearance from the US Food and Drug Administration (FDA) for its new detector-based spectral CT radiotherapy solution.
PET/CT image analysis using artificial intelligence (AI) can predict the occurrence of interstitial lung disease, a serious side effect of immunotherapy in lung cancer, a new study shows.
Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.
Scientists have developed a novel method for deploying several magnetic miniature robots which can easily navigate through a 3D matrix resembling a network of blood vessels.
To take cell therapy in regenerative medicine to a new level, experts consider 3D bioprinting a key technology. However, there are still quality issues that need to be overcome to achieve this.
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
How can innovations help to master challenges and demands in healthcare? This central question will be addressed at the Medica Health IT Forum, an established part of the programme at the trade fair.
Research shows a one-third chance of restoring blood circulation during cardiac arrest, regardless of whether the medication is administered into the bloodstream or bone marrow.
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.
New research suggests that transcranial ultrasound stimulation (TUS) could be used to help people with pain, alcoholism, OCD, and Parkinson’s disease, without drugs or surgery.
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
The year: 2034. Breast cancer patients benefit from perfectly personalised diagnostics and therapies. The tedium of follow-up treatments is a thing of the past, thanks to AI, augmented reality and robotics. Just a tale from the realm of science fiction, or could this soon be clinical reality? At the annual meeting of the German Senologic Society, Prof Dr Marc Thill from the Agaplesion Markus…
Rsearchers developed a novel bioelectronic device that taps into the natural electrical activity of certain bacteria found on our skin, paving the way for a drug-free approach to managing infections.
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.
Telesurgical procedures, new resection techniques, robot-assisted surgery: The sixth Semi-Live conference at University Hospital Heidelberg looked at how surgical approaches have evolved in the last few decades driven by technical advances in the ongoing quest for precision and excellence in patient care.
A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.
Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.
Women with severe native valvular heart disease (VHD) are less likely to be treated in accordance with guidelines than men, finds a new study conducted at more than 200 centres across Europe.
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
Researchers have succeeded in identifying patterns of response to treatment in patients with multiple myeloma using AI tools, which helps to accurately predict the evolution of the tumor.
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
A bit more mucus in the nose, a little less air in the gut: Even small changes can be important when planning proton therapy against cancer. A new workflow allows for an adapted irradiation every day.
STAb-T, a new form of immunotherapy to treat solid tumours shows therapeutic potential in animal models with non-small cell lung cancer. The new strategy is designed to strengthen the defensive cells.
Ultrasound plays a pivotal role in the assessment of organ transplant patients. It enables physicians to safely and easily assess progress, identify complications and resolve problems, as well as deliver long-term monitoring. The value of ultrasound in the transplant space was highlighted in a session at ECR 2024, covering liver, renal, pancreas, paediatric and multi-organ transplants with…
Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.
Currently, it is difficult to predict whether a cancer patient will respond to immunotherapy or not. A new method to quantify the heterogeneity of the tumour microenvironment aims to improve this.
Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.
A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.
Immunocompromised patients are at greatest risk of developing severe Covid-19 after an infection. While early antiviral treatments yield best results, even late-onset therapies still show benefits.
An AI-enabled digital stethoscope could help doctors identify twice as many cases of heart failure during pregnancy compared to regular obstetric care and screening, acording to a new study.
Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.
The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.
Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.
Researchers discovered a gene that might be a key factor in the progression of Huntington’s disease in organoids. The gene may contribute to brain abnormalities much earlier than previously thought.
Brazilian researchers have identified a key mechanism of Sars-CoV-2 to manipulate its host’s immune defense. This discovery could pave the way for the development of novel therapies.
Researchers explore the native bioproduction facilities in bacteria to synthesize a new biopolymer with tissue-healing properties. The resulting hydrogel could be used for muscle tissue regeneration.
New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.
Systemic lupus erythematodes can lead to severe kidney damage. However, until now, the cause for this remained unclear. New research has now revealed the underlying mechanism.
When a person is diagnosed with rectal cancer, part of the bowel is often removed, often resulting in the need for a stoma or problems with bowel control. A new therapy could help avoid this surgery.
Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.
After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.
Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.
A crucial component in joints, cartilage is notoriously difficult to repair. Now, US researchers have developed a promising bioactive material to regenerate cartilage in knee joints.
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
Researchers discovered islands of highly potent immune cells in the vicinity of glioblastomas. This may open up prospects for new therapies for these aggressive brain tumours.
US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.
Radiotherapy of prostate cancer often comes with side effects, causing some patients to discontinue treatment. New research shows the benefits of at lowering the dose over subsequent treatment cycles.
Using vascular organoids derived from stem cells, researchers gain new insights into how diabetes damages blood vessels. This could lead to to the development of new treatments.
The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.
Many medicines require cold storage, which is a challenge for infrastructure and sustainability. Now, researchers designed a hydrogel protecting therapeutics at temperatures as high as 50°C.
Researchers have discovered an Achilles heel of migratory metastatic cells: They now investigate how the cell death mechanism ferroptosis can be utilized for future cancer treatments.
Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.
Enzyme-driven nanorobots could be used in the treatment of joint diseases such as arthritis. A new research project explores the potential of this technology.
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
The nuclear medicine global market is projected to see a significant increase in the coming years, with the lion's share being attributed to radiotherapeutics. So, how to set up a dedicated theranostics centre? At the annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Toronto, Ontario, an entire session was dedicated to planning logistics, radiation safety, and…
The new Nuclear Medicine Department of the San Pietro Fatebenefratelli Hospital was inaugurated in Rome. The Department was inaugurated with the online intervention of Health Minister Orazio Schillaci and in the presence of Maria Tripodi (Undersecretary at the Ministry of Foreign Affairs and International Cooperation), Antonello Aurigemma (President of Lazio Regional Council).
Smaller kills faster – this is what was previously thought about gold nanoparticles used to fight cancer cells. However, new research reveals a more complex picture of these interactions.
A novel blood test shows promise to predict Parkinson's disease in risk patients up to seven years before the typical motor symptoms appear.
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
What is an advanced clinical practitioner (ACP) and why should nuclear medicine technologists strive to become one? At the 2024 annual meeting of the SNMMI in Toronto, ACP Luisa Roldão Pereira outlined the position and its importance in the clinical context.
Finnish researchers found that using a mobile application based on cognitive behavioral therapy can significantly boost success rates of people attempting to stop smoking.
In lab models of stroke, a research team showed that laser therapy improved blood flow in the brain and decreased stroke injury by stimulating the production of nitric oxide.
Scientists discover how the production of antibodies is regulated in allergy and infections. This opens the door to new therapies, without affecting the beneficial response of the immune system.
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
The concept of delivering radiation therapy to cancer patients seated in an upright position is undergoing a major resurgence. Evidence is already highlighting that patients feel more comfortable seated upright and enjoy better communication with radiotherapists during their care. In addition, there are indications of less internal organ movement, enabling more accurate treatment delivery.…
Researchers have developed a technology for targeted stimulation of the brain with ultrasound. This could be used to treat diseases and conditions such as epilepsy, Parkinson’s disease, depression, addiction, and even the aftereffects of stroke.
Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.
Digital twin technology can transform clinical practice by aiding patient-specific prediction and supporting personalized treatment models. Expert speakers at an ECR 2024 session in Vienna focussed on how radiology will play a leading role in the advance through data acquisition via a range of imaging modalities.
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
Microbubbles in a contrast agent allows for ultrasound imaging of the finest vascular details. This is the working principle of a technique called ultrasound localization microscopy (ULM).
For many, the term “metaverse” evokes images of VR headsets and the rebranded company behind Facebook – but can the digital parallel universe provide actual benefits for healthcare? Dr Anke Diehl has studied the technology intensively and recognises significant potential for medical applications. However, the expert for digital transformation at Essen University Medicine, Germany, cautions…
In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.
Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.
Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.
Diagnosing lung conditions such as pulmonary embolism is more challengenging when a patient cannot tolerate contrast agents. Now, a new software solution is addressing the issue.
Delegates from Hannover Medical School and the University of Glasgow have now signed a letter of intent to intensify their collaboration in the field of infection research.
Singing rehabilitates speech production in post-stroke aphasia. Researchers at the University of Helsinki investigated the rehabilitative effect of singing on the brain.
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.
A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).
A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis.
Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.
New research into a life-threatening, but underestimated complication in lung transplants not only provides new insights, but also approaches for early detection and timely treatment.
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
In some patients with multiple sclerosis (MS), symptoms worsen during treatment, but MRI scans do not indicate any change. In such cases, positron emission tomography could help, a new study suggests.
Researchers present a new method for generating human alveolar epithelial type I cells. This could ultimately progress therapies for people living with pulmonary diseases.
Coronary artery disease causes more than 1.8 million heart attacks each year in Europe. In most cases, rehabilitation helps the patients to return to their everyday life. But what happens once the patients have left the rehab clinic?
A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
Decreased rates of death and stroke: new research shows the validity of transcatheter aortic valve replacement in low-risk patients. This advocates a less invasive alternative to surgical options.
Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
Catheter ablation of atrial fibrillation is an important treatment option for heart rhythm maintenance and symptom reduction. Now, an international consensus statement reflects new techniques.
Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
Researchers discovered three distinct immunological endophenotypes of multiple sclerosis, defined by specific blood immune signatures. This opens new avenues for personalized treatment strategies.
A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.
A specific subtype of a microbe commonly found in the mouth has been identified that is able to travel to the gut and grow within colorectal cancer tumors, driving cancer progression.
Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.
A team of Northwestern University scientists has developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn’s disease.
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
Awareness of the importance of women’s health is on the rise, but many challenges remain: At ECR 2024 in Vienna, we spoke with Hologic about their continued evaluation of healthcare efforts for women. At the congress, the company also shared how AI could be used to mitigate the effects of medical staff shortage.
An ageing population and modern lifestyle conditions have greatly increased the case numbers for hip arthroplasty. To prevent complications, it is important for orthopaedic surgeons to identify high-risk patients and take proper precautions. At the Heraeus symposium at DKOU, two experts explored the special measures that should be taken to ensure better outcomes for elderly and frail patients.
Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.
Researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating memory impairment and other cognitive effects of chemotherapy.
In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.
PPE compliance, air and environment monitoring, antibiotic treatment decision support: AI has great potential to help prevent infectious disease outbreaks, a review at the upcoming ECCMID points out.
Breast cancer has no “one size fits all” therapy approach: subtypes differ significantly in malignancy, progression, and treatment response. Therefore, the more is known about the type of carcinoma in a patient, the better the outcome. At the annual scientific EUSOBI meeting in Valencia, Dr Ramona Woitek pointed out the potential of novel imaging techniques and computational image analysis…
An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.
‘Next Generation Radiology: Embracing the future and redefining the field of radiology’: In the run-up to the European Congress of Radiology 2024, we spoke with ESR President Professor Carlo Catalano from Rome, Italy, about the meeting’s content and its intriguing theme.
Patients suffering from cartilage defects in the knee may benefit from a new method in development: Using cartilage from the nose, researchers grow a tailor-made implant.
Cancer patients receiving radiotherapy run the risk of injuring their lungs. This can lead to conditions like pneumonitis and fibrosis. A new cell-by-cell model can help make treatments safer.
Using light instead of x-rays, a new imaging method from Philips is designed to advance navigation through a patient's blood vessels during minimally-ivasive procedures.
GE HealthCare and the European Society of Radiology (ESR) renew their collaboration for the upcoming European Congress of Radiology (ECR) from February 28 to March 3 in Vienna.
A new guideline for the diagnosis and treatment of cryptococcosis is designed to support medical staff in handling invasive fungal infections and provide guidance and support in decision-making.
After a stroke, patients often experience uncontrollable spasms of their arms and hands. Engineers have developed a glove-like wearable medical device that offer relief for the condition.
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.
Heat waves are becoming more common due to climate change. Researchers in Cologne explore what this might mean for the effectiveness of medication.
Chemotherapy can be toxic to heart cells. To help protect the hearts of cancer patients, Cedars-Sinai investigators have created a three-dimensional “heart-on-a-chip” to evaluate drug safety.
Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.
AI technology holds promise for personalised cancer therapies. However, rigid and slow approval requirements impede its introduction, say experts – and point out how this might be changed.
Researchers in Japan and the US have developed technology to robustly augment the amount of MHC class I molecules in cancer cells. This makes them easier to find and destroy for the immune system.
Neuroscientists recently discovered that low-dose ionizing radiation (LDIR) can reduce lesion size and reverse motor deficits in TBI and ischemic stroke mice, demonstrating its therapeutic potential.
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
As a result from better living standards and medical advances, population longevity increases – a development which, paradoxically, current healthcare systems are ill-prepared for, Sir John Bell points out. The UK’s Our Future Health programme, which he chairs, exemplifies the paradigm shift to a prevention-centered healthcare approach.
Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.
The underlying mechanisms of Guillain-Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
New research demonstrates how tiny nanomachines could greatly reduce bladder cancer by precisely targeting the tumour and attacking it with a radioisotope carried on their surface.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
Millions suffer from obesity, an epidemic that continues to trend upward. While bariatric surgery is a very effective treatment option, a new survey reveals common misconceptions about the procedure.
Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.
Long confined to surgery, robots are making their first steps in interventional radiology. Those devices could help improve accuracy in tumour targeting during needle insertion and help less experienced radiologists perform ablations, a leading French interventional radiologist showed at the Spectrum conference in Miami.
Tinnitus is common, affecting up to one in four people. Now a study shows that the debilitating effects on mental health can often be reduced via training and sound therapy in a smartphone app.
A feasibility study by Swiss researchers shows that AI systems are able to reliably predict therapeutic success in patients with borderline personality pathology by detecting emotions on their face.
A research team has successfully developed “NK cell-engaging nanodrones” capable of selectively targeting and eliminating cancer cells, offering a potential solution for intractable cancer types.
Given the limited success of traditional therapies for depression, recent years have witnessed the emergence of technology-based interventions. One such intervention is transcranial electromagnetic stimulation (TMS).
When your stomach is full after a large meal, certain receptors are activated to tell the brain. A newly developed capsule could provoke this fullness signal early, potentially helping with treating obesity.
A low-cost technology involving nano-sized antimicrobial compounds against tuberculosis has been developed by researchers at São Paulo State University (UNESP).
Operating a surgical robot is complicated, but now, researchers may have found a surprising way to shorten the learning process: with electricity applied to the head.
Researchers have created a first-of-its-kind immune cell atlas of the developing lung, revealing coordination between the immune and respiratory systems much earlier than previously thought.
Using AI and optoacoustic imaging, researchers have developed a new method to assess microvascular changes in the skin – and thus the severity of diabetes in the patient.
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
Highlights:Laboratory results influence therapy decisions by 70 to 85 percent. For both the doctor and the patient, it is important that laboratory results are incorporated into therapy decisions quickly and without compromise.The S-Monovette Lithium Heparin Gel+ guarantees reliable sample quality at a reduced TAT: The centrifugation time is reduced by up to 50 percent which enables…
Assays: Clozapine, Risperidone, Aripiprazole, Olanzapine, Quetiapine, Paliperidone Highlights:Antipsychotic drug monitoring provides healthcare professionals accurate and vital information.Testing of antipsychotic drugs can help manage patient therapy by providing greater clarity on the causes of treatment failure (i.e., adherence, drug resistance, drug-drug interactions and drug…
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
According to the European Dementia Monitor, there is still a clear East/West divide, with significant differences between countries in terms of availability, affordability, legal and human rights.
Neurobiologists in Sweden have discovered a way to partially restore communication between nerve cells in the brain after a stroke. This could lead to future treatments, the researchers say.