A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.
In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.
Social deprivation, infectious diseases, broken bones, and even poison apples: The life of Disney princesses is fraught with hidden health risks, a new study reveals.
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Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
Spinal cord stimulation is performed for patients with chronic pain. However, for some patients, the procedure is not effective. A new method involving fMRI could help predict success.
Opposing views on new implantable cardiac devices were aired in a Great Debate session at the European Society of Cardiology’s annual 2024 congress in London. Experts discussed emerging techniques and technologies and debated whether they are actually ready for clinical application. At the core of the session was the issue of whether conduction system pacing (CSP) should replace cardiac…
Precise segmentation of anatomical structures greatly benefits cancer diagnosis. Using AI and deep learning methods, researchers are developing a high-precision 3D viewer software for medical image data.
A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.
US researchers have developed a comprehensive deep learning AI model designed to more accurately identify and classify cells in high-content tissue images.
The current rise in antibiotic resistance is once again sparking interest in phage therapy. Now, scientists developed a new tool that recommends the best possible phage cocktail for a given patient.
A wearable electrical nerve stimulation (TENS) device, which uses low-voltage electrical currents, could help reduce pain, fatigue, and mobility issues associated with long-Covid, a new study finds.
A research team has found wearable organic x-ray sensors could be the answer towards safer radiotherapy protocols for cancer patients, reducing the debilitating side-effects of the treatment.
New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.
Mindray, one of the world's leading developers and providers of advanced medical imaging devices and solutions, launched Resona A20, a premium ultrasound system, at EUROSON 2024 in Naples, Italy.
A newly developed ‘biocooperative’ material based on blood can guide key processes taking place during the natural healing of tissues to create living materials that enhance tissue regeneration.
A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.
Royal Philips announced a major advance in radiation oncology with 510(k) clearance from the US Food and Drug Administration (FDA) for its new detector-based spectral CT radiotherapy solution.
PET/CT image analysis using artificial intelligence (AI) can predict the occurrence of interstitial lung disease, a serious side effect of immunotherapy in lung cancer, a new study shows.
Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.
Scientists have developed a novel method for deploying several magnetic miniature robots which can easily navigate through a 3D matrix resembling a network of blood vessels.
To take cell therapy in regenerative medicine to a new level, experts consider 3D bioprinting a key technology. However, there are still quality issues that need to be overcome to achieve this.
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
How can innovations help to master challenges and demands in healthcare? This central question will be addressed at the Medica Health IT Forum, an established part of the programme at the trade fair.
Research shows a one-third chance of restoring blood circulation during cardiac arrest, regardless of whether the medication is administered into the bloodstream or bone marrow.
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.
New research suggests that transcranial ultrasound stimulation (TUS) could be used to help people with pain, alcoholism, OCD, and Parkinson’s disease, without drugs or surgery.
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
The year: 2034. Breast cancer patients benefit from perfectly personalised diagnostics and therapies. The tedium of follow-up treatments is a thing of the past, thanks to AI, augmented reality and robotics. Just a tale from the realm of science fiction, or could this soon be clinical reality? At the annual meeting of the German Senologic Society, Prof Dr Marc Thill from the Agaplesion Markus…
Rsearchers developed a novel bioelectronic device that taps into the natural electrical activity of certain bacteria found on our skin, paving the way for a drug-free approach to managing infections.
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
New insights into metastasis: Scientists created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells. This could help discover new screening and treatment options.
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.
Telesurgical procedures, new resection techniques, robot-assisted surgery: The sixth Semi-Live conference at University Hospital Heidelberg looked at how surgical approaches have evolved in the last few decades driven by technical advances in the ongoing quest for precision and excellence in patient care.
A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.
Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.
Women with severe native valvular heart disease (VHD) are less likely to be treated in accordance with guidelines than men, finds a new study conducted at more than 200 centres across Europe.
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
Researchers have succeeded in identifying patterns of response to treatment in patients with multiple myeloma using AI tools, which helps to accurately predict the evolution of the tumor.
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
A bit more mucus in the nose, a little less air in the gut: Even small changes can be important when planning proton therapy against cancer. A new workflow allows for an adapted irradiation every day.
STAb-T, a new form of immunotherapy to treat solid tumours shows therapeutic potential in animal models with non-small cell lung cancer. The new strategy is designed to strengthen the defensive cells.
Ultrasound plays a pivotal role in the assessment of organ transplant patients. It enables physicians to safely and easily assess progress, identify complications and resolve problems, as well as deliver long-term monitoring. The value of ultrasound in the transplant space was highlighted in a session at ECR 2024, covering liver, renal, pancreas, paediatric and multi-organ transplants with…
Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.
Currently, it is difficult to predict whether a cancer patient will respond to immunotherapy or not. A new method to quantify the heterogeneity of the tumour microenvironment aims to improve this.
Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.
A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.
Immunocompromised patients are at greatest risk of developing severe Covid-19 after an infection. While early antiviral treatments yield best results, even late-onset therapies still show benefits.
An AI-enabled digital stethoscope could help doctors identify twice as many cases of heart failure during pregnancy compared to regular obstetric care and screening, acording to a new study.
Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.
The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.
Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.
Researchers discovered a gene that might be a key factor in the progression of Huntington’s disease in organoids. The gene may contribute to brain abnormalities much earlier than previously thought.
Brazilian researchers have identified a key mechanism of Sars-CoV-2 to manipulate its host’s immune defense. This discovery could pave the way for the development of novel therapies.
Researchers explore the native bioproduction facilities in bacteria to synthesize a new biopolymer with tissue-healing properties. The resulting hydrogel could be used for muscle tissue regeneration.
New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.
Systemic lupus erythematodes can lead to severe kidney damage. However, until now, the cause for this remained unclear. New research has now revealed the underlying mechanism.
When a person is diagnosed with rectal cancer, part of the bowel is often removed, often resulting in the need for a stoma or problems with bowel control. A new therapy could help avoid this surgery.
Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.
After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.
Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.
A crucial component in joints, cartilage is notoriously difficult to repair. Now, US researchers have developed a promising bioactive material to regenerate cartilage in knee joints.
Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.
Researchers discovered islands of highly potent immune cells in the vicinity of glioblastomas. This may open up prospects for new therapies for these aggressive brain tumours.
US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.
Radiotherapy of prostate cancer often comes with side effects, causing some patients to discontinue treatment. New research shows the benefits of at lowering the dose over subsequent treatment cycles.
Using vascular organoids derived from stem cells, researchers gain new insights into how diabetes damages blood vessels. This could lead to to the development of new treatments.
The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.
Many medicines require cold storage, which is a challenge for infrastructure and sustainability. Now, researchers designed a hydrogel protecting therapeutics at temperatures as high as 50°C.
Researchers have discovered an Achilles heel of migratory metastatic cells: They now investigate how the cell death mechanism ferroptosis can be utilized for future cancer treatments.
Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.
Enzyme-driven nanorobots could be used in the treatment of joint diseases such as arthritis. A new research project explores the potential of this technology.
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
The nuclear medicine global market is projected to see a significant increase in the coming years, with the lion's share being attributed to radiotherapeutics. So, how to set up a dedicated theranostics centre? At the annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) in Toronto, Ontario, an entire session was dedicated to planning logistics, radiation safety, and…
The new Nuclear Medicine Department of the San Pietro Fatebenefratelli Hospital was inaugurated in Rome. The Department was inaugurated with the online intervention of Health Minister Orazio Schillaci and in the presence of Maria Tripodi (Undersecretary at the Ministry of Foreign Affairs and International Cooperation), Antonello Aurigemma (President of Lazio Regional Council).
Smaller kills faster – this is what was previously thought about gold nanoparticles used to fight cancer cells. However, new research reveals a more complex picture of these interactions.
A novel blood test shows promise to predict Parkinson's disease in risk patients up to seven years before the typical motor symptoms appear.
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
What is an advanced clinical practitioner (ACP) and why should nuclear medicine technologists strive to become one? At the 2024 annual meeting of the SNMMI in Toronto, ACP Luisa Roldão Pereira outlined the position and its importance in the clinical context.
Finnish researchers found that using a mobile application based on cognitive behavioral therapy can significantly boost success rates of people attempting to stop smoking.
In lab models of stroke, a research team showed that laser therapy improved blood flow in the brain and decreased stroke injury by stimulating the production of nitric oxide.
Scientists discover how the production of antibodies is regulated in allergy and infections. This opens the door to new therapies, without affecting the beneficial response of the immune system.
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
The concept of delivering radiation therapy to cancer patients seated in an upright position is undergoing a major resurgence. Evidence is already highlighting that patients feel more comfortable seated upright and enjoy better communication with radiotherapists during their care. In addition, there are indications of less internal organ movement, enabling more accurate treatment delivery.…
Researchers have developed a technology for targeted stimulation of the brain with ultrasound. This could be used to treat diseases and conditions such as epilepsy, Parkinson’s disease, depression, addiction, and even the aftereffects of stroke.
Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.
Digital twin technology can transform clinical practice by aiding patient-specific prediction and supporting personalized treatment models. Expert speakers at an ECR 2024 session in Vienna focussed on how radiology will play a leading role in the advance through data acquisition via a range of imaging modalities.
The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the smallest tumour cells.
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
Microbubbles in a contrast agent allows for ultrasound imaging of the finest vascular details. This is the working principle of a technique called ultrasound localization microscopy (ULM).
For many, the term “metaverse” evokes images of VR headsets and the rebranded company behind Facebook – but can the digital parallel universe provide actual benefits for healthcare? Dr Anke Diehl has studied the technology intensively and recognises significant potential for medical applications. However, the expert for digital transformation at Essen University Medicine, Germany, cautions…
In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.
Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.
Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.
Diagnosing lung conditions such as pulmonary embolism is more challengenging when a patient cannot tolerate contrast agents. Now, a new software solution is addressing the issue.
Delegates from Hannover Medical School and the University of Glasgow have now signed a letter of intent to intensify their collaboration in the field of infection research.
Singing rehabilitates speech production in post-stroke aphasia. Researchers at the University of Helsinki investigated the rehabilitative effect of singing on the brain.
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.
A new study suggests superiority of the novel investigational PET imaging agent ⁶⁸Ga-DPI-4452 (Debio 0328) to standard CT imaging in the context of clear cell renal cell cancer (ccRCC).
A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis.
Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.
New research into a life-threatening, but underestimated complication in lung transplants not only provides new insights, but also approaches for early detection and timely treatment.
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
In some patients with multiple sclerosis (MS), symptoms worsen during treatment, but MRI scans do not indicate any change. In such cases, positron emission tomography could help, a new study suggests.
Researchers present a new method for generating human alveolar epithelial type I cells. This could ultimately progress therapies for people living with pulmonary diseases.
Coronary artery disease causes more than 1.8 million heart attacks each year in Europe. In most cases, rehabilitation helps the patients to return to their everyday life. But what happens once the patients have left the rehab clinic?
A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
Decreased rates of death and stroke: new research shows the validity of transcatheter aortic valve replacement in low-risk patients. This advocates a less invasive alternative to surgical options.
Bacteria can help – or hinder – the treatment of cancer. How this happens, however, is largely unknown. Now, researchers have mapped bacteria in cancer metastases to shed more light on their role.
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
Catheter ablation of atrial fibrillation is an important treatment option for heart rhythm maintenance and symptom reduction. Now, an international consensus statement reflects new techniques.
Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.
Researchers discovered three distinct immunological endophenotypes of multiple sclerosis, defined by specific blood immune signatures. This opens new avenues for personalized treatment strategies.
A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.
A specific subtype of a microbe commonly found in the mouth has been identified that is able to travel to the gut and grow within colorectal cancer tumors, driving cancer progression.
Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.
A team of Northwestern University scientists has developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn’s disease.
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
Awareness of the importance of women’s health is on the rise, but many challenges remain: At ECR 2024 in Vienna, we spoke with Hologic about their continued evaluation of healthcare efforts for women. At the congress, the company also shared how AI could be used to mitigate the effects of medical staff shortage.
An ageing population and modern lifestyle conditions have greatly increased the case numbers for hip arthroplasty. To prevent complications, it is important for orthopaedic surgeons to identify high-risk patients and take proper precautions. At the Heraeus symposium at DKOU, two experts explored the special measures that should be taken to ensure better outcomes for elderly and frail patients.
Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.
Researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating memory impairment and other cognitive effects of chemotherapy.
In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.
PPE compliance, air and environment monitoring, antibiotic treatment decision support: AI has great potential to help prevent infectious disease outbreaks, a review at the upcoming ECCMID points out.
Breast cancer has no “one size fits all” therapy approach: subtypes differ significantly in malignancy, progression, and treatment response. Therefore, the more is known about the type of carcinoma in a patient, the better the outcome. At the annual scientific EUSOBI meeting in Valencia, Dr Ramona Woitek pointed out the potential of novel imaging techniques and computational image analysis…
An innovative solution based on nanotechnology and ultrasound could prevent over-treatment of patients with rectal cancer. The magnetomotive ultrasound system uses nanotechnology for reliable diagnosis of any spread of rectal cancer to nearby lymph nodes.
‘Next Generation Radiology: Embracing the future and redefining the field of radiology’: In the run-up to the European Congress of Radiology 2024, we spoke with ESR President Professor Carlo Catalano from Rome, Italy, about the meeting’s content and its intriguing theme.
Patients suffering from cartilage defects in the knee may benefit from a new method in development: Using cartilage from the nose, researchers grow a tailor-made implant.
Cancer patients receiving radiotherapy run the risk of injuring their lungs. This can lead to conditions like pneumonitis and fibrosis. A new cell-by-cell model can help make treatments safer.
Using light instead of x-rays, a new imaging method from Philips is designed to advance navigation through a patient's blood vessels during minimally-ivasive procedures.
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GE HealthCare and the European Society of Radiology (ESR) renew their collaboration for the upcoming European Congress of Radiology (ECR) from February 28 to March 3 in Vienna.
A new guideline for the diagnosis and treatment of cryptococcosis is designed to support medical staff in handling invasive fungal infections and provide guidance and support in decision-making.
After a stroke, patients often experience uncontrollable spasms of their arms and hands. Engineers have developed a glove-like wearable medical device that offer relief for the condition.
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.
Heat waves are becoming more common due to climate change. Researchers in Cologne explore what this might mean for the effectiveness of medication.
Chemotherapy can be toxic to heart cells. To help protect the hearts of cancer patients, Cedars-Sinai investigators have created a three-dimensional “heart-on-a-chip” to evaluate drug safety.
Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.
AI technology holds promise for personalised cancer therapies. However, rigid and slow approval requirements impede its introduction, say experts – and point out how this might be changed.
Researchers in Japan and the US have developed technology to robustly augment the amount of MHC class I molecules in cancer cells. This makes them easier to find and destroy for the immune system.
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Neuroscientists recently discovered that low-dose ionizing radiation (LDIR) can reduce lesion size and reverse motor deficits in TBI and ischemic stroke mice, demonstrating its therapeutic potential.
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
As a result from better living standards and medical advances, population longevity increases – a development which, paradoxically, current healthcare systems are ill-prepared for, Sir John Bell points out. The UK’s Our Future Health programme, which he chairs, exemplifies the paradigm shift to a prevention-centered healthcare approach.
Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.
The underlying mechanisms of Guillain-Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.
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Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
New research demonstrates how tiny nanomachines could greatly reduce bladder cancer by precisely targeting the tumour and attacking it with a radioisotope carried on their surface.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
Millions suffer from obesity, an epidemic that continues to trend upward. While bariatric surgery is a very effective treatment option, a new survey reveals common misconceptions about the procedure.
Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.
Long confined to surgery, robots are making their first steps in interventional radiology. Those devices could help improve accuracy in tumour targeting during needle insertion and help less experienced radiologists perform ablations, a leading French interventional radiologist showed at the Spectrum conference in Miami.
Tinnitus is common, affecting up to one in four people. Now a study shows that the debilitating effects on mental health can often be reduced via training and sound therapy in a smartphone app.
A feasibility study by Swiss researchers shows that AI systems are able to reliably predict therapeutic success in patients with borderline personality pathology by detecting emotions on their face.
A research team has successfully developed “NK cell-engaging nanodrones” capable of selectively targeting and eliminating cancer cells, offering a potential solution for intractable cancer types.
Given the limited success of traditional therapies for depression, recent years have witnessed the emergence of technology-based interventions. One such intervention is transcranial electromagnetic stimulation (TMS).
When your stomach is full after a large meal, certain receptors are activated to tell the brain. A newly developed capsule could provoke this fullness signal early, potentially helping with treating obesity.
A low-cost technology involving nano-sized antimicrobial compounds against tuberculosis has been developed by researchers at São Paulo State University (UNESP).
Operating a surgical robot is complicated, but now, researchers may have found a surprising way to shorten the learning process: with electricity applied to the head.
Researchers have created a first-of-its-kind immune cell atlas of the developing lung, revealing coordination between the immune and respiratory systems much earlier than previously thought.
Using AI and optoacoustic imaging, researchers have developed a new method to assess microvascular changes in the skin – and thus the severity of diabetes in the patient.
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
Assays: Clozapine, Risperidone, Aripiprazole, Olanzapine, Quetiapine, Paliperidone Highlights:Antipsychotic drug monitoring provides healthcare professionals accurate and vital information.Testing of antipsychotic drugs can help manage patient therapy by providing greater clarity on the causes of treatment failure (i.e., adherence, drug resistance, drug-drug interactions and drug…
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White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
According to the European Dementia Monitor, there is still a clear East/West divide, with significant differences between countries in terms of availability, affordability, legal and human rights.
Neurobiologists in Sweden have discovered a way to partially restore communication between nerve cells in the brain after a stroke. This could lead to future treatments, the researchers say.
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
In a new study, UCLA researchers demonstrated how small cell neuroendocrine prostate cancer tumor cells can arise from less aggressive prostate tumors.
Ten times more detail than current 7T scanners, over 50 times more than 3T: A new type of functional MRI will allow neuroscientists to more precisely localize and trace brain networks.
New research suggests a new approach to precision radiotherapy can reduce the risk of swallowing problems for patients, without impacting the success of treatment.
Scientific articles about psiorasis suffer from a shortage of actual patient images, according to a new study. This makes it hard for patients to grasp the condition, the authors argue.
Drinking more than three liters of fluid per day may be a harmless habit – or a warning sign for a rare hormone deficiency. Swiss researchers investigated tests to differentiate between the two.
Bone scans have been found to overstage prostate cancer at initial staging compared to prostate specific membrane antigen (PSMA) PET, according to new research.
In the last few years, virtual reality has become a very significant tool in therapeutic applications, for example, to overcome deep-seated fears or the lack of empathy in abusers.
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
Diagnosing early-stage lung cancer with low-dose CT screening dramatically improves the long-term survival rate of cancer patients, a large-scale, 20-year international study shows.
A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.
MEDICA trade fair (Nov 13-16, Düsseldorf) is a major event for start-ups entering the health sector. Hundreds of young developers seek business contacts for cooperation concerning funding, production, approval, marketing or sales of their products.
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
Philips and Quibim have signed a multi-year agreement to work on an integrated solution including an AI-based software to automate real-time prostate gland segmentation in MR images.
New trial results suggest that a short course of induction chemotherapy prior to chemoradiation could reduce the rate of relapse and death among patients with locally advanced cervical cancer.
A collaborative study, led by Cima Universidad de Navarra, has identified key epigenetic targets for the treatment of hepatoblastoma, the most frequent liver cancer in childhood.
Chronic wounds in diabetes patients are often slow to heal, which can lead to serious infections and even limb amputation. Now, researchers propose to address this with a magnetic wound-healing gel.
University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.
When a woman becomes pregnant, sometimes her pre-existing rheumatoid arthritis will 'magically' go away. In others, the condition becomes even worse. Now, US researchers may have found an explanation.
Highlights Nowadays 3D plays a key role in high risk procedures such as aneurysm coiling, AVM / Fistula embolization, endovascular aortic aneurysm repair, etc. The Alphenix Sky+ incorporates state-of-the-art technologies allowing 3D body coverage at 80°/sec covering a range of 210°, from head to toe without any patient or table movement and free head access. Helping clinicians…
A team of researchers from Vienna has discovered that dormant breast cancer tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein.
University of Oxford researchers demonstrated that neural cells can be 3D printed to mimic the architecture of the cerebral cortex. This could be used in patients after brain injuries.
A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.
Researchers in Spain have developed a system using patient cells which represents the first 3D muscle model capable of replicating the damage caused by Duchenne muscular dystrophy (DMD).
After pelvic radiotherapy, patients may live with low-grade chronic inflammation of the lower intestine 20 years after the treatment, a new study shows.
Researchers at the University of Michigan have zeroed in on Candida auris – a fungus with the uncanny ability to stick to everything from skin to catheters – and made a startling discovery.
US researchers have discovered that radiation therapy combined with two types of immunotherapy can control tumors in preclinical models of triple negative breast cancer.
Swiss scientists report that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across spinal cord injuries and guide nerves to reconnect to their natural targets.
New methods to predict outcomes for pregnancies where there are issues with poor growth of the baby inside the womb have been developed by a team of scientists.
A new onco-therapeutic vaccine candidate against human papillomavirus (HPV)-induced cancers, such as cervical and oropharyngeal cancers, has shown promising results in the preclinical phase.
Modern cancer therapies are tough on the tumours, but often, also on the heart of the patients. The “CARDIOCARE” project aims to reduce the cardiac burden of anti-cancer therapies through more patient-tailored treatment approaches. At the ESC 2023 cardiology congress, Professor Katerina Naka from the project’s consortium explained why older patients are at the highest risk of cardiotoxic…
A team at Politecnico di Milano developed iHEART, a mathematical and computational model of the human heart designed for studying coronary artery disease.
A newly discovered mechanism involving exosomes can drive inflammation and impair healing of wounds in diabetes patients, according to a new study led by University of Pittsburgh and UPMC researchers.
From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.
A new research breakthrough could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis.
A new type of microdevice could offer new ways to treat brain cancer. The shape and size of a grain of rice, it is implanted into a tumor to study the effects of ongoing therapies.
For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).
Experts from Brigham and Women’s Hospital have tasked ChatGPT to generate recommendations for cancer treatment – with some promise, but ultimately inadequate results.
Cardiologists in Zurich demonstrate that immediate revascularization of non-involved blood vessels offers better outcomes for patients after a heart attack than a delayed procedure.
Patients with immunodeficiency cannot benefit from conventional Covid-19 vaccines and still at risk from infection. A promising new approach now brings hope for this patient group.
Machines are getting smarter every day, and companies across the world are discovering new ways in which they can use AI to significantly enhance engagement and customer experience. That is why decision-makers from pharmaceutical companies, hospitals and healthcare providers gather to network and discuss the latest innovations, as well as the potential for both AI and robotics, at Healthcare…
A new analysis exploring the finances of bringing new cancer drugs to market has found that precision oncology drugs could be $1 billion cheaper to develop than non-precision drugs.
Experts presented state-of-the-art and emerging techniques to treat chest tumours and discussed common issues in the management of pneumothorax at RSNA 2022. Current ablation methods in the thorax include radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation (CRYO), irreversible electroporation (IRE) and pulsed electric field.
Centralized review of slides combined with telepathology has opened up the potential for a dramatic reduction in the waiting times for breast cancer patients to start their therapy. Jan Hudecek from the Netherlands Cancer Institute outlined his team’s framework for multi-centre clinical trials with centralized digital pathology review at the 9th Digital Pathology and Artificial Intelligence…
Brain tumour progression to a malignant state is believed to be the result of an intricate interplay between cancer cells and the tumour microenvironment. Greek researchers shed new light on the mechanisms.
In a new editorial paper, researchers from the Army Hospital Hamburg discuss treatment strategies for common, but highly malignant types of head and neck tumors.
German bioinformaticians have now detected an unexpected diversity of certain cell appendages in the bacterium Acinetobacter baumannii that are associated with its pathogenicity.
ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia: beta thalassaemia and sickle cell anaemia.
While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.
Researchers have unveiled a key mechanism of breast cancer cells to infiltrate lymph nodes. The discovery may lead to new metastasis-blocking treatments and improve patients’ lives.
Researchers at Mayo Clinic have developed a 3D prototype of human skin bioprinted to model inflammatory skin disease such as atopic dermatitis — more commonly known as eczema.
AI can use data from low-dose CT scans of the lungs to improve risk prediction for death from lung cancer, cardiovascular disease and other causes, a new study finds.
A new study by investigators from Brigham and Women’s Hospital demonstrates the potential for restoring fertility when the ovaries have stopped working.
A new study led by researchers from the University of Notre Dame links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors.
Combining two types of heart scan techniques could help doctors to detect deadly hypertrophic cardiomyopathy (HCM) before symptoms and signs on conventional tests appear.
Scientists have developed a tool to create a digital replica of an individual's heart, which could inform the diagnosis and treatment of cardiovascular diseases.
The International Alzheimer's Congress (AAIC) in Amsterdam saw the presentation of new guidelines for diagnosing Alzheimer's disease - with blood biomarkers taking a central role.
A new device could monitor and treat heart disease and dysfunction in the days, weeks or months following traumatic heart-related events — and harmlessly dissolve afterwards.
Treatment times for radiotherapy could be reduced for some early breast cancer patients, according to a trial led by University of Cambridge and The Institute of Cancer Research, London.
Post-pandemic problems, ageing societies, the impact of climate change on human health: To find solutions for new and ongoing healthcare challenges, thinking outside the box is crucial. This year’s Medical Taiwan Health & Care Expo took this approach to heart: True to its motto “beyond healthcare”, the event showcased a wide range of innovative products, promising start-up presentations…
A new PET tracer, 89Zr-DFO-girentuximab, can accurately detect a type of kidney cancer called clear cell renal cell carcinoma and differentiate it from other types of kidney tumors.
The combination of curettage and cryosurgery is safe and effective for treating the most common form of skin cancer, basal cell carcinoma, a study from the University of Gothenburg shows.
While it’s true that AI holds tremendous potential for improving the science and practice of psychotherapy, it remains a definitively high-stakes area. Stanford experts define the potential benefits and concerns of deploying the technology.
A new US-led study shows that astrocyte brain cells play an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.
For proton radiation therapy against cancer, there is yet no direct method for mapping the beam range during dose delivery. A new method devised by Dresden scientists could help.
Results from a large European study reinforce the use of Extracorporeal photopheresis (ECP) in heart transplant patients as a treatment for heart transplant rejection and prevention of rejection.
Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…