Search for: "Parkinson’s disease" - 145 articles found

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Unprecedented improvements

Gene therapy 'reprograms' cells to reverse AADC deficiency

A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities. The study, led by researchers at The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine, offers new hope to those living with incurable genetic and neurodegenerative diseases.

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Sonothermogenetics

Tool activates deep brain neurons by combining ultrasound, genetics

Neurological disorders such as Parkinson’s disease and epilepsy have had some treatment success with deep brain stimulation, but those require surgical device implantation. A multidisciplinary team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely…

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Neuroscience

A deep dive into the brain

Researchers from ETH Zurich and University of Zurich have developed a new microscopy technique that lights up the brain with high resolution imagery. This allows neuroscientists to study brain functions and ailments more closely and non-​invasively.

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Battle for the brain

New Alzheimer's treatment approach targets tau

A new idea for treating Alzheimer’s disease could eradicate the toxic proteins most closely linked to cognitive decline in the places where they do the most damage, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests. The study was published online in Science Translational Medicine.

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dPCR and HSAFM

Low-cost technique for missed genetic mutations

A new low-cost method targeting genetic mutations often missed by existing diagnostic approaches has been developed. Researchers at Virginia Commonwealth University (VCU) in the United States noted that most rearrangement mutations implicated in cancer and neurological diseases fall between what can be detected by DNA sequence reads and optical microscopy methods. The new technique combines…

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Merging modalities

AI combines ECG and X-ray to diagnose arrhythmic disorders

Kobe University Hospital’s Dr. Makoto Nishimori and Project Assistant Professor Kunihiko Kiuchi et al. (of the Division of Cardiovascular Medicine, Department of Internal Medicine) have developed an AI that uses multiple kinds of test data to predict the location of surplus pathways in the heart called ‘accessory pathways’, which cause the heart to beat irregularly. In this study, the…

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Reparative hydrogel

Fixing traumatic head injury with 'brain glue'

At a cost of $38 billion a year, an estimated 5.3 million people are living with a permanent disability related to traumatic brain injury (TBI) in the United States today, according to the Centers for Disease Control and Prevention. The physical, mental and financial toll of a TBI can be enormous, but new research from the University of Georgia provides promise. In a new study, researchers at…

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Mass spectrometry analysis

Skin swabs can detect Covid-19

Skin swab samples analysed using mass spectrometry could be used to detect Covid-19 in patients, according to research conducted at the University of Surrey in the UK. Current Covid-19 testing is via a polymerase chain reaction (PCR) test, which involves taking a swab of the back of the throat and inside the nose, but the team from Surrey - working with Frimley NHS Trust and the Universities of…

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AI uncovers neurological changes

Facial analysis algorithm to track Parkinson’s Disease

Parkinson’s disease (PD) usually causes facial abnormalities that affect a person’s self-esteem and relationships. However, these abnormalities are difficult to analyze quantitatively with current methods. To address this issue, scientists from Okayama University, Japan, explored whether commercial AI-based facial analysis software could be useful in this context. Their results show that…

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Degenerative disease diagnostics

Parkinson's: Scientists develop ‘game-changing’ skin swab test

It is possible to identify Parkinson’s Disease based on compounds found on the surface of skin, according to new research. The findings offer hope that a pioneering new test could be developed to diagnose the degenerative condition through a simple and painless skin swab. Scientists at The University of Manchester have developed a technique which works by analysing compounds found in sebum -…

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iPSC research

'Brain cell grafts' hold promise for reversing Parkinson’s symptoms

Grafting neurons grown from monkeys’ own cells into their brains relieved the debilitating movement and depression symptoms associated with Parkinson’s disease, researchers at the University of Wisconsin–Madison report. In a study published in the journal Nature Medicine, the team describes its success with neurons made from induced pluripotent stem cells from the monkeys’ own bodies.…

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Microbiome research

'Organs-on-a-chip' system sheds light on interactions between gut and brain

In many ways, our brain and our digestive tract are deeply connected. Feeling nervous may lead to physical pain in the stomach, while hunger signals from the gut make us feel irritable. Recent studies have even suggested that the bacteria living in our gut can influence some neurological diseases. Modeling these complex interactions in animals such as mice is difficult to do, because their…

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Alternative to traditional surgery

Focused ultrasound shows promise for Parkinson’s treatment

A scalpel-free alternative to brain surgery has the potential to benefit people with Parkinson’s disease symptoms that are much more severe on one side of the body, new research suggests. More testing is needed, but the approach, which uses a technology called focused ultrasound, could offer a new option for patients whose symptoms are poorly controlled by medications and those who cannot or do…

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Crossing the blood-brain barrier

Nanoparticle drug-delivery system to treat brain disorders

In the past few decades, researchers have identified biological pathways leading to neurodegenerative diseases and developed promising molecular agents to target them. However, the translation of these findings into clinically approved treatments has progressed at a much slower rate, in part because of the challenges scientists face in delivering therapeutics across the blood-brain barrier (BBB)…

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spotlight at virtual.MEDICA

Digital health is on the rise due to COVID-19

MEDICA in Düsseldorf is a world-leading platform for the medical technology business and the healthcare industry and has always been one of the places to be for the entire sector as it covers current digital health trends, innovative products and services for linking all of the major stakeholders in medical care. Consequently, digital health is a mainstay of virtual.MEDICA, which, due to the…

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Nitrogen dioxide levels

Air pollution linked to higher COVID-19 mortality

Scientists have unearthed a possible link between the severity of COVID-19 and air quality. The preliminary study – looking at whether areas with higher levels of air pollutants in England are associated with a larger number of cases/deaths from COVID-19 – was conducted by a team from the University of Cambridge. Aware of the effects that air pollutants have on human health – and that…

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Origins of the disease(s) explained

Parkinson's: not one, but two diseases?

Although the name may suggest otherwise, Parkinson's disease is not one but two diseases, starting either in the brain or in the intestines. Which explains why patients with Parkinson’s describe widely differing symptoms, and points towards personalised medicine as the way forward for people with Parkinson's disease. This is the conclusion of a study which has just been published in the leading…

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Cardiology research

Predicting longevity in heart failure patients - by looking at their eyes

Pupil size predicts death and hospital readmission in patients with heart failure, according to new research. “Our results suggest that pupil area is a novel way to identify heart patients at elevated risk of death or hospital readmission,” said study author Dr. Kohei Nozaki of Kitasato University Hospital, Kanagawa, Japan. “This provides an opportunity to intervene and improve outlook.”

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FDG-PET imaging of the brain

The nuclear medicine approach to Alzheimer’s

Nuclear Medicine techniques have an important role in the clinical diagnosis of patients with cognitive impairment. And such techniques are not only valuable in a clinical setting but also in research, according one of the leading experts in the field, Javier Arbizu, who is Professor of Radiology and Nuclear Medicine at the Faculty of Medicine at the University of Navarra, Spain.

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First biomarker for regenerative medicine

MRI predicts efficacy of stem cell therapy for brain injury

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Loma Linda University Health have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury—a first-ever “biomarker” for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve…

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Wearable against diabetic retinopathy

Smart contact lenses for diabetes diagnosis and treatment

Diabetes is called an incurable disease because once it develops, it does not disappear regardless of treatment in modern medicine. Having diabetes means a life-long obligation of insulin shots and monitoring of blood glucose levels. Recently, a research team at Pohang University of Science and Technology developed a wirelessly driven ‘smart contact lens’ technology that can detect diabetes…

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A look at oligodendrocytes

Parkinson’s disease may start in the gut

Researchers at Karolinska Institutet and the University of North Carolina have mapped out the cell types behind various brain disorders. The findings are published in Nature Genetics and offer a roadmap for the development of new therapies to target neurological and psychiatric disorders.

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Reducing side effects

Nanohybrid vehicles to deliver drugs into the human body

Researchers in The University of Texas at El Paso’s (UTEP) Department of Chemistry and Biochemistry have developed a nanohybrid vehicle that can be used to optimally deliver drugs into the human body. The research was published in ACS Applied Materials & Interfaces. Leading the study are Mahesh Narayan, Ph.D., professor, and Sreeprasad Sreenivasan, Ph.D., assistant professor, both from the…

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Look out!

Eye movement test confirms brain-ageing effects

University of Liverpool researchers have used a newly developed eye movement test to improve the understanding of how parts of the brain work. Healthy, older adults are widely reported to experience cognitive decline, including impairments in inhibitory control (the ability to stop ourselves thinking or doing things). However, because ageing effects on inhibitory control are highly variable…

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Finding treatment for Parkinson's disease

Synthetic neurons could take brain research to the next level

The body can recover from many things, but the damage caused by Parkinson’s disease isn’t one of them. No cure exists for Parkinson’s, which 1 million people in the U.S. are expected to be living with by 2020. But an outright cure isn’t the primary objective of research by Chongli Yuan, a Purdue University chemical engineering professor and leader of Purdue’s section of a…

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Molecular diversity

New insights into abnormal proteins in Parkinson’s disease and MSA

Parkinson’s and multisystem atrophy (MSA) – both of them neurodegenerative diseases – are associated with the accumulation of alpha-synuclein proteins in the brain. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Max Planck Institute for Biophysical Chemistry (MPI-BPC) have investigated the molecular makeup of these protein deposits finding structural…

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Neurology

Overcoming the blood-brain-barrier: Delivering therapeutics to brain

For the first time, scientists have found a way that can effectively transport medication into the brain - which could lead to improved treatments for neurological and neurodegenerative diseases. In a study, scientists from Newcastle University have led an international team in a major breakthrough in unlocking the secrets of how medications can infiltrate the brain.

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Oncology

Killing the unkillable cancer cells

We all know someone affected by the battle against cancer. And we know that treatments can be quite efficient at shrinking the tumor but too often, they can’t kill all the cells, and so it may come back. With some aggressive types of cancer, the problem is so great that there is very little that can be done for the patients.

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Up in smoke

Early exposure to nicotine predisposes brain to addiction

Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a study published in Biological Psychiatry. A UC San Diego School of Medicine team of scientists, headed by senior author Davide Dulcis, PhD, associate professor in the…

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CMT, Alzheimer's, Parkinson's

Study links key protein to Charcot-Marie-Tooth and other nerve diseases

A new study provides critical insight into a little-known, yet relatively common, inherited neurological condition called Charcot-Marie-Tooth disease (CMT). The findings point to a pathway to possible treatments for this disease and better understanding of other neurodegenerative disorders, including Alzheimer's disease, that affect millions. The study focused on two related proteins, MFN2 and…

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Unique detection

'Super smeller' could lead to parkinson skin swab test

A study has identified chemicals in the skin responsible for a unique scent in people with Parkinson’s disease. The chemicals can be detected in an oily substance secreted from the skin called sebum, the researchers found. The findings suggest Parkinson’s disease could one day be diagnosed from skin swabs, potentially leading to new tests. There are no tests for Parkinson’s disease at…

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Endoprosthetics

Joint efforts: New guidelines for arthroplasty

According to the Swedish Knee Arthroplasty Register, knee arthroplasty – with a revision rate of five percent after ten years – is one of the most successful surgical interventions of the post-World War II decades. The most frequent reasons for revision are loosening or infections, whereas patient dissatisfaction is often caused by mobility impairment and pain. Since many adverse events are…

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Get some rest

Sleep deprivation accelerates Alzheimer’s brain damage

Poor sleep has long been linked with Alzheimer’s disease, but researchers have understood little about how sleep disruptions drive the disease. Now, studying mice and people, researchers at Washington University School of Medicine in St. Louis have found that sleep deprivation increases levels of the key Alzheimer’s protein tau. And, in follow-up studies in the mice, the research team has…

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Wireless WAND

Can 'pacemaker for the brain' help to treat neurological disorders?

A new neurostimulator developed by engineers at the University of California, Berkeley, can listen to and stimulate electric current in the brain at the same time, potentially delivering fine-tuned treatments to patients with diseases like epilepsy and Parkinson's. The device, named the WAND, works like a "pacemaker for the brain," monitoring the brain's electrical activity and…

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Neurology

Focused ultrasound: CE Mark for Exablate Neuro

Siemens Healthineers and Insightec announce the CE clearance of Exablate Neuro compatible with Magnetom Skyra, Prisma and Prisma Fit scanners from Siemens Healthineers. Exablate Neuro uses focused ultrasound for treatments deep within the brain with no surgical incisions. MR imaging provides a complete anatomical survey of the treatment area, patient-specific planning and real-time outcome…

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Gait analysis

What your walk says about your health

The way you walk can reveal current and future health problems. New research from Halmstad University suggests the use of wearable sensors for analysing your movement. This can potentially result in early detection of for example Parkinson’s disease, dementia, multiple sclerosis and other neuro-physiological disorders. Many of our body systems, such as the cardio-vascular system and the…

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Pivotal trial

Parkinson's disease: First patient treated with focused ultrasound

The first patient in a multicenter pivotal trial using focused ultrasound to address the major motor symptoms of Parkinson’s disease has been treated at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center in New York. This randomized, double-blind clinical trial is evaluating the safety and efficacy of using Insightec’s Exablate Neuro device in more than 100 patients…

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GCCA/GBCA safety

Gadolinium @ ECR 2018 – diverse and “disunited”?

Gadolinium-containing/gadolinium-based contrast agents (GCCAs/GBCAs) and their usage was a major topic at ECR 2018. Fuelled by the current debate a number of presentations focused on possible impact, risks and necessities. Some were highly specific, others took a broader view. The only consensus, however, seems to be the need for more research and the focus on safety. Three ECR speakers, Joseph…

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Alzheimer’s, Parkinson’s and Huntington’s

The role of misfolded proteins in neurodegenerative diseases

Alzheimer’s, Parkinson’s and Huntington’s disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three. A recent study by David Smith, associate professor of biochemistry in the West Virginia University School of Medicine, suggests that at the heart of all three…

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Triggering inflammatory reactions

Parkinson’s gene initiates disease outside of the brain

Until very recently, Parkinson’s had been thought a disease that starts in the brain, destroying motion centers and resulting in tremors and loss of movement. New research published this week, shows the most common Parkinson’s gene mutation may change how immune cells react to generic infections like colds, which in turn trigger the inflammatory reaction in the brain that causes…

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New test

Tears don't lie – they may even help diagnose Parkinson’s

Tears may hold clues to whether someone has Parkinson’s disease, according to a preliminary study released that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018. “We believe our research is the first to show that tears may be a reliable, inexpensive and noninvasive biological marker of Parkinson’s disease,” said study…

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AEC syndrome

Cause of severe genetic disease identified

Mutations in the p63 protein lead to a number of disorders, but none is as severe as the AEC syndrome. Scientists at Goethe University Frankfurt in collaboration with a research group from the University of Naples Federico II have now discovered that this syndrome resembles diseases such as Alzheimer’s, Parkinson’s or ALS more closely than it does other p63-based syndromes. Their results,…

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In sheep's clothing

Research examines a different culprit behind Alzheimer's disease

What if one of the prime suspects behind Alzheimer’s disease was a case of mistaken identity? Amyloid plaques, sticky buildup that accumulates in and around neurons in the brain, have long been believed to be an indicator of neurodegenerative disease. Most clinical drug trials for Alzheimer’s disease treatment have failed, presumably because they target these plaques. But according to Raymond…

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High levels, low levels

How caffeine may help diagnose Parkinson’s disease

Testing the level of caffeine in the blood may provide a simple way to aid the diagnosis of Parkinson’s disease, according to a study published in the online issue of Neurology, the medical journal of the American Academy of Neurology. The study found that people with Parkinson’s disease had significantly lower levels of caffeine in their blood than people without the disease, even if they…

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"Stormram 4"

This 3D-printed robot could be the future of cancer treatment

Cancer surgeons perform an estimated 1.7 breast biopsies each year, according to the American Association of Preferred Provider Organizations. This makes the procedure a significant proportion of cases referred to anatomic pathologists. This surgery, however, is time-consuming and not always accurate due to shortcomings in existing surgical technology and to human error. Now, a 3D-printed…

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Research

Experimental drug interferes with Alzheimer’s mechanisms

The chemical compound “anle138b” eases cognitive deficits and normalizes gene expression in a mouse model of Alzheimer’s disease. Furthermore, the drug seems to close harmful openings in the membrane of nerve cells. An international collaboration reports these findings in the journal “EMBO Molecular Medicine”. The scientists suggest that anle138b should be validated in clinical trials…

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Clever peptides

Biomarker may predict early Alzheimer’s disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a peptide that could lead to the early detection of Alzheimer’s disease (AD). The discovery, published in Nature Communications, may also provide a means of homing drugs to diseased areas of the brain to treat AD, Parkinson’s disease, as well as glioblastoma, brain injuries and stroke. “Our goal was to…

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Neurotransmissions

Nanosensors uncloak the mysteries of brain chemistry

Nanosensors are incredible information-gathering tools for myriad applications, including molecular targets such as the brain. Neurotransmitter molecules govern brain function through chemistry found deep within the brain, so University of California, Berkeley researchers are developing nanosensors to gain a better understanding of exactly how this all plays out. During the AVS 64th…

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Protein quality control system

Cellular power outage

A common feature of neurodegenerative diseases are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions. Scientists report that, even in normal cells, aberrant aggregation-prone proteins are continually produced due to partial failure of the respiratory system. Unless they are removed by degradation, aggregates accumulate preferentially in the…

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Cell activity

Individual receptors caught at work

G protein-coupled receptors (GPCRs) are among the "hottest” targets for the therapy of diseases such as hypertension, asthma or Parkinson's. These receptors are the site of action of many hormones and neurotransmitters and allow them to regulate the activity of our cells. How and where this happens has long been the subject of numerous hypotheses. An international team of scientists from…

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Biology of Ageing

Road map to a longer life

In old age a variety of cellular processes decline and the risk to develop age-related diseases such as Alzheimer’s, Parkinson’s or Diabetes increases dramatically. But does ageing affect all organs and tissues in the body in the same way? And should drugs that are developed to improve health in old age have the same effect on every organ? Now scientists from the Max Planck Institute for…

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Predicting cognitive decline

Odor identification problems may be a warning bell for dementia

A long-term study of nearly 3,000 adults, aged 57 to 85, found that those who could not identify at least four out of five common odors were more than twice as likely as those with a normal sense of smell to develop dementia within five years. Although 78 percent of those tested were normal – correctly identifying at least four out of five scents – about 14 percent could name just three out…

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Neurological diseases

No health without brain health

A largely aged population is already a reality in some countries, and this will become a worldwide problem by 2047, when the number of the Earth’s old people is likely to surpass the number of young people.

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Ophthalmology

New eye test detects earliest signs of glaucoma

A simple eye test could help solve the biggest global cause of irreversible blindness, glaucoma. In clinical trials, the pioneering diagnostic test - developed by researchers at UCL Institute of Ophthalmology and the Western Eye Hospital - allowed doctors to see individual nerve cell death in the back of the eye.

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Sarcoidosis

Penn Medicine Launches First Apple ResearchKit App for Sarcoidosis Patients

Penn Medicine today launched its first Apple ResearchKit app, focused on patients with sarcoidosis, an inflammatory condition that can affect the lungs, skin, eyes, heart, brain, and other organs. The effort marks Penn’s first time using modules from Apple’s ResearchKit framework, as part of the institution’s focus on mobile health and innovative research strategies.

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Alzheimer's

Concussion linked to brain changes in people at genetic risk for Alzheimer's

Moderate-to-severe traumatic brain injury is a known risk factor for diseases that gradually destroy the brain - such as late-onset Alzheimer's disease. Now, a new study links mild traumatic brain injury, or concussion, in people at genetic risk for Alzheimer's to accelerated brain deterioration and mental decline associated with the disease.

breath samples

You are what you exhale

An international team of 56 researchers in five countries has confirmed a hypothesis first proposed by the ancient Greeks – that different diseases are characterized by different “chemical signatures” identifiable in breath samples. The findings by the team led by Professor Hossam Haick of the Technion-Israel Institute of Technology Department of Chemical Engineering and Russell Berrie…

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Study

Molecular Roots of Alzheimer’s

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.

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Neurodegenerative diseases

Brain cell ‘executioner’ identified

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's. Now, researchers at Johns Hopkins say they have pinpointed the protein at the end of that chain of events, one that delivers the fatal strike by carving up a cell's DNA. The find, they say, potentially…

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For tissue engineering

Technique generates human neural stem cells

Tufts University researchers have discovered a new technique for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications, including a three-dimensional model of the human brain, according to a paper published in Stem Cell Reports. The work could pave the way for experiments that engineer other innervated tissues, such as the skin and…

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Stroke

Imaging in intra-arterial interventions

Stroke patients will first undergo a CT scan as they enter the hospital. Before any further imaging scan is carried out, the medical team must decide whether they need to intervene intra or extra cranially. ‘Imaging enables you to see which pathology you are dealing with and helps you select patients for either recanalisation or revascularisation or, in some cases, occlusion by embolisation,’…

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Infection control

Scientists gain ground against resistance

The mechanism by which drug-resistant bacteria maintain a defensive barrier has been identified by researchers at England’s University of East Anglia (UEA) and their findings could result in a new wave of drugs that can bring down those defensive walls rather than attack the bacteria – thus they may not develop drug-resistance at all.

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heat-shock

HSF1 – in case of emergency

When there is an accident or a house fire, we call the police or the fire services. A control room quickly coordinates emergency operations. The cells in our bodies also have helpers in a crisis; the heat-shock proteins. These are triggered in response to cellular stress, such as high temperature, UV radiation or cancer. Heat-shock proteins help other proteins maintain their functional structure…

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Bioengineering

Squeezing cells into stem cells

École polytechnique fédérale de Lausanne (EPFL) scientists have developed a new method that turns cells into stem cells by "squeezing" them. The method paves the way for large-scale production of stem cells for medical purposes.

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Neurodegenerative diseases

The case of the sticky protein

Proteins are like a body’s in-house Lego set. These large, complex molecules are made up of building blocks called amino acids. Most of the time, proteins fold correctly, but sometimes they can misfold. This misfolding causes the proteins to get sticky, and that can promote clumping, or aggregation, which is the hallmark of several neurodegenerative diseases such as ALS, Alzheimer’s and…

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Neurology

Improved brain implants

By implanting electrodes in the brain tissue one can stimulate or capture signals from different areas of the brain. These types of brain implants, or neuro-prostheses as they are sometimes called, are used to treat Parkinson's disease and other neurological diseases.

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Parkinson’s Disease

Noninvasive brain stimulation improves motor symptoms

People with Parkinson’s disease (PD) tend to slow down and decrease the intensity of their movements even though many retain the ability to move more quickly and forcefully. Now, in proof-of-concept experiments with “joysticks” that measure force, a team of Johns Hopkins scientists report evidence that the slowdown likely arises from the brain’s “cost/benefit analysis,” which gets…

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Fighting AIDS

Targeting HIV in semen to shut down AIDS

There may be two new ways to fight AIDS -- using a heat shock protein or a small molecule – to attack fibrils in semen associated with the human immunodeficiency virus (HIV) during the initial phases of infection, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

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Event

International Day of Radiology

Radiology will be in the spotlight on November 8, as radiologists celebrate the International Day of Radiology (IDoR) through a series of events and information campaigns to help the public better understand the role of medical imaging in healthcare.

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Chronic disease

There is a global shortage of doctors that is getting worse every year. With the demographic shift in many countries from a predominantly young to an increasing aging population, a steep increase in chronic disease is occurring.

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Gene Therapy in the EU

For the first time, a EU agency recommends a gene therapy drug for commercial release in Europe. The European Medicine's Agency announced in late July 2012 that its Committee for Medicinal Products for Human Use (CHMP) recommends Glybera for commercial release in the European Union

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Determining the site of deep brain implants

Uncontrollable convulsions, tremor or spasms can considerably impair the lives of neurodegenerative disease patients. Deep brain stimulation (DBS) – for which tiny electrodes are implanted in the brain to stimulate the target areas continuously with electrical impulses – can significantly reduce the movement disorder.

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The European Health Forum Gastein

More than 600 distinguished guests from 40 countries are expected at this year’s European Health Forum Gastein (EHFG). ‘Since its foundation in 1998, the EHFG has developed into an international meeting point for the highest-ranking healthcare politicians, managers and scientists from all over the world,’ said EHFG President Professor Günther Leiner.

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Costs of Parkinson's disease differ greatly between countries

Care for Parkinson's patients can cost between 5,240 and 19,620 Euro a year. This has been shown in a study done in six European countries by the European Cooperative Network for Research, Diagnosis and Therapy of Parkinson’s Disease (EuroPa). The results are presented at the European Neurology Congress in Berlin. The goal of the study was a comprehensive comparison of health care costs

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Neurological diseases on the rise

„Diseases of the nervous system and the brain occur more frequently than cancer. According to recent calculations of health care costs, they represent a burden of 386 billion euros a year on European economies,“ says Prof. Gérard Said, newly elected president of the European Neurological Society (ENS) at the annual meeting in Berlin, Germany. „This is often greatly underestimated.“

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Diagnosis, Management, Treatment

EPDA Champions Change for People with Parkinson’s Disease in Europe

To mark the first European Parkinson’s Action Day on April 12th, the European Parkinson’s Disease Association (EPDA) announced the launch of a major new investigation into the care of people with Parkinson’s across 36 European countries. Parkinson’s disease is the second most common progressive neurodegenerative condition which affects people from all around the world.

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NHS needs to invest in increasing specialists´nurses

The Royal College of Nursing (RCN) has joined forces with almost 40 of the UK's leading health organisations to warn that cutting specialist nurse services for people with long term conditions would be a "false economy", as they began a campaign for guaranteed access to specialist nursing care for all patients with long term conditions.

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Handwriting revisited

A specialised brain area involved in the production of written language was first empirically described by 19th century scientist S. Exner. At that time, the only way to investigate was by post mortem study of patients who had experienced writing problems during their lives. Now, in France, a team of researchers led by Jean François Démonet, has applied state-of-the art technology to study…

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Parkinson's Disease: genetic risk factors identified

Two genes containing mutations known to cause rare familial forms of parkinsonism are also associated with the more common, sporadic form of the disease where there is no family history, researchers have found. An International study reveals common gene variants in people of European descent.

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The first whole-body MRI-PET system

The technological integration of positron emission tomography (PET) and magnetic resonance imaging (MRI) has been the dream of molecular imaging experts and engineers for some time. Now, the German Science Council has agreed to provide 6.56 million funding to install a whole-body MRI-PET prototype in the centre of excellence for imaging procedures at the radiology clinic in Eberhard-Karls…

Safeguarding the future of MRI

Europe holds a leading position in the research and development of MRI, which has been used for over 25 years, imaging up to 500 million patients without evidence of harm to workers due to EMF exposure. It is also well known that MRI is free from health risks associated with ionising radiation such as X-rays, in many situations the alternative to MRI

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Tasty and healthy food against chronic diseases

Now it seems to be proven: The reason why people in Mediterranean countries live longer and healthier can be connected with their nutrition. Researchers in Italy found that sticking rigidly to a full Mediterranean diet can help reduce deaths from major chronic diseases like heart disease, cancer, Parkinson's and Alzheimer's disease.

Eat Mediterranean to stay healthy

Mediterranean diet protects against chronic diseases like heart disease, cancer, Parkinson's and Alzheimer's disease. Italian scientists bolstering one more time the idea that low intake of meat, dairy products and alcohol, but high intake of vegetables, fruits, nuts, olive oil, grains and fish servers as a model of healthy eating, according to a study in the British Medical Journal.

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Improved and faster analysis of MR images

Thanks to a new software, MR images from a five-minute scan may generate the images for a complete and comprehensive examination and therefore eliminating the need to perform multiple scans. The advanced software developed by Synthetic MR AB will be offered as a clinical application in Sectra´s PACS system.

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First human ultrahigh-field MRI installed in the Netherlands

The Virtual Institute for Seven Tesla Applications (VISTA) is a partnership of several Dutch universities. To evaluate the benefit of ultrahigh-field MRI the first human 7.0T whole-body research scanner, supplied by Philips Medical Systems, was installed at the Leiden University Medical Center (LUMC). Roland Plasterk, the Durch minister of education, culture and science, attended at the opening…

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World's first human brain images scanned with a PET/MRI hybrid system

The next-generation of hybrid imaging technology was presented at this years SNM meeting in Washington, D.C: The first human brain images from a prototype PET/MRI system, which is developed by a collaborative team of German and US researchers from the Universities of Tübingen and Tennessee, as well as Siemens Medical Solutions.

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Treating Alzheimer with a skin patch

“Exelon Patch”, developed by Novartis is the first skin patch to treat patients with mild to moderate Alzheimer disease. The new therapy that has already been approved by the FDA, is said to be more compliant for it causes less incidents of nausea and vomiting.

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Molecular imaging

GE was the first to undertake molecular imaging development on a large scale. 'You have to be a very special company to work in this discipline,' Reinaldo Garcia, President and Chief Executive Officer of GE Healthcare International, pointed out, when we asked for an update on his company's progress in this field

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7-TESLA

Mastering the “uncontrollable beast” By Brenda Marsh, Editor, European Hospital.

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Freezing cardiology

Cryoablation – a safer therapy for children with arrhythmias

Freezing abnormal electrical pathways in the hearts of young patients may be a safer alternative to zapping them with powerful radiofrequency probes to treat tachycardias and other arrhythmias, according to Dr Fabrizio Drago, of the Bambino Gesù Hospital, Rome. ‘If you have a child with a supraventricular tachycardia due to a re-entry circuit, or a target very close to the atrioventricular…

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PET scanning the heart cuts costs

USA - Using positron emission tomography (PET) scanning rather than other types of imaging as the first tool to diagnose heart-vessel blockages is more accurate, less invasive and saves money, according to researchers reporting at the American College of Cardiology's Annual Scientific Session in March.

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