Treating Alzheimer with a skin patch

“Exelon Patch”, developed by Novartis is the first skin patch to treat patients with mild to moderate Alzheimer disease. The new therapy that has already been approved by the FDA, is said to be more compliant for it causes less incidents of nausea and vomiting.

Photo: Treating Alzheimer with a skin patch
The FDA also approved the Exelon Patch for the treatment of patients with mild to moderate Parkinson´s disease dementia, a common disorder that affects about 20 % of Parkinson patients.
Exelon Patch is a transdermal patch which can be applied to the back, the chest or the upper arm of the patient and supplies the organism with a steady bloodstream level of the drug rivastigmine for 24 hours. This method extends the drug´s tolerability and its effectiveness over a wider range of patients, e.g. those who are not able to take the oral capsule version because of the increased prevalence of gastrointestinal side effects: Due to a study the patch version resulted in three times fewer incidents of nausea and vomiting compared to the oral capsule.
The new product should be available in US pharmacies soon. It was also submitted for approval in the European Union.
Dieser Artikel ist auch auf Deutsch vorhanden, bitte klicken Sie hier, um ihn zu lesen!


More on the subject:
Read all latest stories

Related articles


Medication chemistry

Stabilising drugs with 'heavy' hydrogen

A new method involving deuterium can be used to stabilise compounds against degradation. This discovery could result in new drugs that can be taken in lower doses or less frequently.


Covid-19 protection

Needle-free coronavirus vaccine enters clinical trial

Safety trials are underway for a Cambridge-led vaccine that could be used as a booster targeting Covid-19 virus variants and relatives that threaten future coronavirus pandemics.


Additive manufacturing

3D printed medication activated by smartphone screen

The light from a smartphone screen can be used to print medications, in a new 3D printing technique developed by UCL researchers.

Subscribe to Newsletter