With a field strength of 11.7 T, the Iseult MRI machine currently is the most powerful scanner of its kind. Now, the first images of a living human brain showcase impressive resolution.
New research could revolutionize noninvasive monitoring of blood glucose levels (BGLs): a Japanese team developed a novel methodology to estimate BGLs from near-infrared light (NIR) measurements.
Adults who had amblyopia (lazy eye) in childhood are more likely to experience hypertension, obesity, and metabolic syndrome as an adult, as well as a higher heart attack risk, finds a new study.
Researchers have found a surprising method to reduce blood glucose levels in a person: Shining red light on their back. This could help control diabetes without medication.
Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.
A team from the UK and Turkey have developed a contact lens with embedded micro-sensors which can detect changes in eye pressure - a possible indicator of glaucoma.
A nationwide programme to reduce the risk of developing diabetes in the United Kingdom is proven beyond reasonable doubt to work, a new study reveals.
Chronic wounds in diabetes patients are often slow to heal, which can lead to serious infections and even limb amputation. Now, researchers propose to address this with a magnetic wound-healing gel.
University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.
The earlier it starts, the more type 2 diabetes shaves off of a person's life expectancy. For people in their 30s, this can be as much as 14 years less, new research finds.
Engineers from MIT are developing a device containing insulin-producing cells and a tiny oxygen-producing factory to keep the cells of diabetes patients healthy.
A team from Geneva demonstrates the value of imaging to detect the presence of tau protein in the brain to predict cognitive decline due to Alzheimer’s disease.
The risk for poor glycemic control in patients with type 2 diabetes can be predicted with confidence by using machine learning methods, a new study from Finland finds.
A device using next-gen technology to automatically deliver insulin was found to be more effective at maintaining blood glucose levels than standard-of-care management for type 1 diabetes.
Development of effective live bacterial therapeutics may depend more on using and re-introducing native microbes that can stick around than how the microbes are modified.
A new device, which doesn’t rely on immunosuppressing drugs, may assist efforts to develop an artificial pancreas to treat diabetes.
Similar to the way exercise helps muscles adapt to workouts, short, repeated bouts of reduced circulation with a blood pressure cuff may help prevent the worst outcomes of heart attacks and strokes.
This overview introduces connected and continuous glucose sensing technologies, smart insulin delivery systems and more innovations that help patients and doctors monitor and manage glucose levels and guide decision-making in diabetes care.
Silk-based material under skin changes color in response to oxygen, and in the future might be adapted to track glucose and other blood components.
Engineers have developed a prototype of a wearable that can continuously monitor several health stats—glucose, alcohol, and lactate levels—simultaneously in real-time.
Researchers developed a new microfluidic chip with broad applications for detecting viruses, pathogens, bacteria and other biomarkers in liquid samples.
In order to better prevent and restore fertility and reduce the risk of sterility in cancer survivors, researchers investigate the mechanisms behind negative effects of chemotherapy.
Point-of-care testing (POCT) is a “win-win” scenario for patients and healthcare professionals in delivering care when and where it is needed, according to pathologist Adil Khan, MSc, PhD.
The advantages and limitations of the value of traceability chains in therapeutic drug monitoring will be explored during a key session at the EuroMedLab event.
The number of gamified mobile applications is rising rapidly—especially in healthcare. Gamified apps or devices are used in many fields, from mental health therapy to stroke rehab to managing metabolic conditions. This article illustrates how gamification is employed in diabetes care.
Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…
This year as every year, the very best in global HealthTech will be converging on Dusseldorf for the Medica trade fair. With more than 127 companies attending the event from November 15-18, France will have one of the largest contingents there. Grouped together under the brand umbrella of “French Healthcare”, the French MedTech companies will be presenting their many innovations to industry…
Considerable advances in point-of-care testing (POCT) devices are emerging from lab-on-a-chip platforms, innovations in smartphone-based technology and wearable technology. Cloud-based deep learning systems herald a future revolution.
Plasma glucose levels are essential for the evaluation of diabetes mellitus as well as gestational diabetes. Diabetes mellitus is one of the most common metabolic disorders in the world. The breakdown of glucose (glycolysis) in venous blood samples is of great significance in pre-analytics, particularly in relation to the diagnosis of diabetes mellitus and gestational diabetes. Greiner Bio-One…
Tumour metabolism can be imaged with MRI as a technique to help determine cancer aggressiveness and response to therapy. The work by a UK-based group, on probing cancer metabolism non-invasively with clinical hyperpolarised carbon-13 MRI, can detect metabolic changes in the tumour. As metabolic changes occur much earlier than change in tumour size, this could have implications for quicker…
Plasma glucose levels are essential for the evaluation of diabetes mellitus as well as gestational diabetes. Diabetes mellitus is one of the most common metabolic disorders in the world. The breakdown of glucose (glycolysis) in venous blood samples is of great significance in pre-analytics, particularly in relation to the diagnosis of diabetes mellitus and gestational diabetes.
Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer’s levels of glucose as well as lactate, alcohol or caffeine. It is the first wearable device that monitors cardiovascular signals and multiple biochemical levels in the human body at the same…
Coronavirus-associated concerns dominate the Top 10 list of important technology hazard risks for hospitals, in an annual report published by ECRI, a nonprofit technology Pennsylvania research firm. The list is derived from ECRI’s team of technology experts who monitor hospital and healthcare organizations, and published to inform healthcare facilities about important safety issues involving…
All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases. This is shown in a study by the Institute for Diabetes Research and Metabolic Diseases (IDM) of Helmholtz Zentrum München at the University of Tübingen,…
A software tool to predict the most effective therapy for non-small cell lung cancer (NSCLC) developed by applying deep learning artificial intelligence (AI) to positron emission tomography/computed tomography (PET/CT) images has been developed by researchers at H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida. The tool is designed to provide a noninvasive, accurate method to…
In 2019, the Central Laboratory of the Institute for Clinical Chemistry and Pathobiochemistry at the Klinikum rechts der Isar of the Technical University Munich, headed by Professor Peter B Luppa, organised the 4th of the internationally renowned Munich Point-of-Care Testing Symposiums. Dr Andreas Bietenbeck is senior physician at the Institute which for many years has been focusing on…
Focused on updating healthcare through digitisation, 41 experts and around 500 delegates gathered for the 4th ‘Digital Health Conference’ late in 2019. At the Berlin venue, they focused on solutions such as the potential lack of skilled staff, demographic changes, urbanisation and multimorbidity.
A research team co-led by a scientist at City University of Hong Kong (CityU) has discovered a new, non-invasive way to detect early-stage Alzheimer’s disease, helping patients get the necessary treatments around 10 years before any symptoms appear. In collaboration with Johns Hopkins University in the US, Dr Kannie Chan Wai-yan, Associate Professor in the Department of Biomedical Engineering…
Whole body diffusion-weighted magnetic resonance imaging (DW MRI) may aid in the assessment of cancer treatment response in children and youth at much lower levels of radiation than current approaches, suggests a small study funded by the National Institutes of Health. The results appear in Radiology. Researchers compared DW MRI, which measures the density of tumors by tracking the movement of…
Diabetes is called an incurable disease because once it develops, it does not disappear regardless of treatment in modern medicine. Having diabetes means a life-long obligation of insulin shots and monitoring of blood glucose levels. Recently, a research team at Pohang University of Science and Technology developed a wirelessly driven ‘smart contact lens’ technology that can detect diabetes…
The world’s first licensed, downloadable artificial pancreas app for people with type 1 diabetes now launched, based on over a decade of research by Professor Roman Hovorka at the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. The CamAPS FX app works with an insulin pump and a glucose monitor to automatically deliver insulin to people living with the condition…
Radiology, pathology, medical genetics and laboratory medicine under one roof: many hospitals are toying with the idea of ‘integrated diagnostics’ but it was the medical management at Geneva’s University Hospital that dared to take the first step and consolidate all these diagnostic disciplines in a single organisational unit: The Diagnostic Department. ‘Our long-term vision is a…
An organic compound produced by the gut flora – the metabolite 4-Cresol – is considered to have protective effects against both type 1 and 2 diabetes, notably by stimulating the growth of the insulin-producing pancreatic beta cells. This is according to a new study led by Inserm researcher Dominique Gauguier at the Environmental Toxicology, Therapeutic Targets, Cell Signaling and Biomarkers…
MRI is now indispensable for diagnosing diseases and monitoring therapies. However, the ongoing discussion on gadolinium deposits in the brain has intensified the search for alternatives. Dr Daniel Paech of the German Cancer Research Centre in Heidelberg, Germany, discussed potential solutions to acquire high-quality images without contrast agents.
Stevens Institute of Technology has signed an exclusive licensing agreement with Bonbouton, giving the company the right to use and further develop a graphene sensing system that detects early signs of foot ulcers before they form, so diabetic patients can access preventative healthcare and manage their health.
Obesity not only means someone is overweight but, over time, they will probably suffer sequelae that increasingly impair quality of life and are potentially fatal – these include hypertension, coronary heart disease, type two diabetes, pulmonary function disorders, tumours, plus an increased risk during surgery and anaesthesia. In patients with morbid obesity, class three obesity, according to…
Getting a good night’s sleep is important and insufficient sleep has been linked to poor health in many studies. Analysing data collected from wearable trackers, researchers from the SingHealth Duke-NUS Institute of Precision Medicine (PRISM) and the National Heart Centre Singapore (NHCS) recently demonstrated that chronic sleep deprivation is associated with increased cardiovascular disease…
A photonics tech company from Vilnius are on their path to solve the 50-year-old task of making non-invasive blood analysis possible. With the help of a unique broadband laser-based sensor, the scientists and engineers at Brolis Sensor Technology are able to remotely sense concentration level of main critical blood constituents such as lactate, glucose, urea, ketones or ethanol without drawing…
The results of a major study across 195 countries, presented at UEG Week Barcelona 2019, indicate that global death rates for pancreatic cancer and incidence rates for colorectal cancer both increased by 10% between 1990 and 2017. The Global Burden of Disease study, is the first to provide comprehensive worldwide estimates of the burden, epidemiological features and risk factors of a number of…
A study of nearly half a million people has found for the first time that those with heart or blood vessel problems benefit more from having a physically active lifestyle than do healthy people without cardiovascular disease (CVD). Increased physical activity reduced the risk of dying during a six-year follow-up period for people with and without CVD, but the researchers found the greatest…
Fourteen metabolic biomarkers can predict long term mortality in individuals helping to determine life expectancy in general populations, a new study in the journal Nature Communications reports. In the largest study of its kind, researchers from Leiden University Medical Center in the Netherlands and the University of Surrey investigated predictors of long-term mortality risk. Current predictors…
A recent study can help governments understand which diagnostic laboratory tests are most important when developing universal health coverage systems. Researchers from five countries found that diagnostic laboratory tests are used similarly around the world, even though the institutions they studied differed in terms of poverty levels, health systems and prevalence of disease. “Even though…
It’s undeniable: the bulk of our population is growing older. Yet, this demographic change has not altered laboratory medicine: the reference values for many analyses are still based on data of a younger cohort. Inevitably this could lead to serious errors in the interpretation of older patients’ test results.
More than a third of people with Type 2 diabetes who took part in a weight management programme delivered by the NHS through GP surgeries remain free of diabetes two years later. These latest findings of the Diabetes Remission Clinical Trial (DiRECT), funded by Diabetes UK and led by experts at Newcastle University and the University of Glasgow, were announced today at Diabetes UK’s…
UC San Francisco researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes. Replacing these cells, which are lost in patients with T1 diabetes, has long been a dream of regenerative medicine, but until now scientists had not been able to figure out how to produce cells in a…
A diagnosis of prediabetes should be a warning for people to make lifestyle changes to prevent both full-blown diabetes and cardiovascular disease (CVD), according to scientists at Wake Forest School of Medicine.
New research by the University of Bristol in collaboration with Medical Detection Dogs has found that the best trained alert dogs have the potential to vastly improve the quality of life of people living with Type 1 diabetes. As reported in PLOS One, on average trained dogs alerted their owners to 83 per cent of hypoglycaemic episodes in over 4,000 hypo- and hyper-glycaemic episodes that were…
Using a common type of brain scan, researchers programmed a machine learning algorithm to diagnose early-stage Alzheimer's disease about six years before a clinical diagnosis is made – potentially giving doctors a chance to intervene with treatment.
Chronic stress is a well-known risk factor for the development of psychiatric illnesses including depression disorders. The brain requires a great deal of glucose, and stress is known to alter glucose metabolism. However, if stress-associated mental impairments are linked to affected glucose metabolism remains to be seen. Researchers at the Department for Psychiatry and Psychotherapy at the Mainz…
Researchers recently evaluated the accuracy of a technology to monitor blood glucose levels without needles or a finger prick. Early results show that the noninvasive technology measures blood glucose levels as effectively as a finger prick test — without drawing blood.
Lab-on-a-chip devices harness electrical signals to measure glucose, discern blood type and detect viruses or cancer. But biological samples need hafnium oxide for protection from electric fields.
According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub. The research found that soaking in a hot tub several times per week for two months results in improved measures of cardiovascular health, beneficial changes in fat tissue and other improvements…
An epidemiological study conducted by researchers at University of California San Diego School of Medicine and Seoul National University suggests that persons deficient in vitamin D may be at much greater risk of developing diabetes. The scientists studied a cohort of 903 healthy adults (mean age: 74) with no indications of either pre-diabetes or diabetes during clinic visits from 1997 to 1999,…
In a mouse study, a drug that has helped millions of people around the world manage their diabetes might also help people ready to kick their nicotine habits. In a report published in The Proceedings of the National Academy of Sciences of the United States of America (PNAS), investigators say metformin, an inexpensive drug commonly used to treat patients with type 2 diabetes, appears to block…
Diabetic eye disease is the leading cause of blindness among people ages 40 to 60. The longer you have diabetes, the greater your likelihood of developing vision problems increases. Keeping blood sugar, blood pressure and cholesterol levels under control can help people with diabetes maintain good eye health. They must also have a dilated eye exam once a year, says Dr. Malav Joshi, an…
Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. First, they silence a key cellular enzyme, and then they add a powerful drug. They describe their methods in a new paper published in Nature Communications. This research could accelerate the development of new treatments for liver cancer,…
Move over, lab-on-a-chip and lab-on-paper. There’s a new diagnostic technology in research labs that is gaining credibility. It is called lab-on-skin technology and some scientists are quite excited about how it might be used for a variety of clinical purposes. A recent story published in ACS Nano titled, “Lab-on-Skin: A Review of Flexible and Stretchable Electronics for Wearable Health…
Type 2 diabetes, which affects >0.5 billion people worldwide, results from the inability of beta cells in the pancreatic islets to provide the body with enough insulin to maintain blood glucose levels within the range for a healthy life. A collaborative study led by Prof. Michele Solimena at the Technische Universität in Dresden as well as the Helmholtz Zentrum München, Dr. Anke M Schulte at…
Just two decades ago, even though promising, point-of-care testing (POCT) was only used in hospitals and surgeries by a small number of specialists. Today POCT is in use throughout healthcare.
Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the University of North Carolina and NC State have now developed what could be a much more patient-friendly option: artificial cells that automatically release insulin into the bloodstream when glucose levels…
For POCT, point-of-care testing, a lab has to purchase new equipment, perform new measurements and handle new parameters – right? Right! However, more importantly, POCT requires the adaptation and integration of the existing lab organisation, with all its consequences, from additional quality control down to new areas of responsibility. Dr Herbert Stekel is currently integrating three…
Over seven million people were using remote monitoring in 2016, mainly for cardiac rhythm management (CRM) and sleep apnoea therapy. The number of users will soar as they can increasingly connect to servers and clouds, Swedish analyst Anders Frick predicts.
Celebrating 40 years of PCI, cardiologists fret over their future with big data, machine learning and robots.
German researches have linked the increased production of a certain enzyme in the liver to fatty liver and insulin resistance.
One in four patients in a university hospital suffers from diabetes (22 percent), and again as many suffer from prediabetes (24 percent), a current study finds. Furthermore, patients with diabetes have prolonged hospital stays and a higher risk of complications.
Scientists from the German Cancer Research Center (DKFZ), in collaboration with colleagues from Heidelberg University Hospital, have been able to visualize brain cancer using a novel MRI method. They use a simple sugar solution instead of conventional contrast agents, which can have side effects in the body.
Many diabetes patients must inject themselves with insulin, sometimes several times a day, while others take medications orally to control blood sugar. The injections, as well as the side effects from both regimens, can be painful. Now, one team reports in the Journal of the American Chemical Society progress toward an insulin-free diabetes treatment that requires fewer injections.
All cancer tumors have one thing in common – they must feed themselves to grow and spread, a difficult feat since they are usually in a tumor microenvironment with limited nutrients and oxygen. A study at The University of Texas MD Anderson Cancer Center has revealed new details about how an enzyme called acetyl-CoA synthetase 2 (ACSS2) allows brain tumors to grow despite their harsh…
Research published in Experimental Physiology shows that diabetes-induced changes in heartbeat are primarily regulated by the β1-adrenoceptor. This discovery, once confirmed in humans, may lead to better treatment of heart problems in diabetics by enabling more targeted drugs to be produced.
New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop. While many cancers are more common among those with diabetes, cancerous brain tumors called gliomas are less common among those with elevated blood sugar and diabetes, a study from The Ohio State University has found. The discovery builds…
Laboratory medicine delivery, regulation and accreditation vary between countries, e.g. Norway, Serbia and France recently aired at FiLM 2017. Leading figures explained the shape, scope and funding of healthcare and lab services and roles played by different professionals and challenges they face.
Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient’s immune system attacks, or “rejects,” the donated organ.
A novel population of neurons that are only activated following chronic stress is identified. Today, stress is part of everyday life. However, when stress is chronic it can lead to distressing illnesses such as depression and anxiety disorders. In their latest study, scientists at the Max Planck Institute of Psychiatry in Munich have identified a population of neurons in the hypothalamus that…
A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells. The team of researchers led by Prof. Michael Hall at the Biozentrum of the University of Basel has also reported that specific cancer cells respond to this combination of drugs.
ETH Researchers have used the simplest approach yet to produce artificial beta cells from human kidney cells. Like their natural model, the artificial cells act as both sugar sensors and insulin producers.
The power of computing grows more pervasive as it is increasingly integrated into everyday items within our immediate environment, as in smart toothbrushes, for example, or a vortex whistle for managing chronic lung function via smartphones. This September, scientists, developers and designers from around the world met in Heidelberg, Germany, for two parallel events: ACM International Joint…
Decision makers from all sectors of the international health industry meet again in Düsseldorf from Monday to Thursday. The world’s biggest medical trade fair, MEDICA 2016, and COMPAMED 2016, as the international leading trade fair for suppliers of the medical technology industry, take place from 14 to 17 November.
Some significant changes in the European hospital sector have occurred over the last 20 years. ‘The necessity to contain the exploding costs in particular has led to a reduction in the number of hospitals and hospital beds, and staffing levels have also been affected by the many cost cutting measures. This has not been without its consequences, as we now know,’ writes Ludwig F Rutten.
Insulin deficiency and hyperglycemia are two well-known culprits behind diabetes, both of which are reflected in blood glucose concentrations. Now, researchers are working to create ultrasensitive lab-on-a-chip devices to quickly measure glucose concentrations with the goal of developing device for early diagnosis and prevent of diabetes.
Identifying a blood disorder may be as easy as running a blood sample from a finger prick under a smartphone. That is the concept behind a new biomedical device being developed by Kansas State University researchers.
In patients suffering from Type 1 diabetes, the immune system attacks the pancreas, eventually leaving patients without the ability to naturally control blood sugar. These patients must carefully monitor the amount of sugar in their blood, measuring it several times a day and then injecting themselves with insulin to keep their blood sugar levels within a healthy range. However, precise control…
Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.
While most Down syndrome research has focused on the brain, a new report by Johns Hopkins University biologists uncovers how the disorder hampers a separate part of the nervous system that plays a key role in health and longevity.
What doesn't kill you could cure you. A growing interest in the therapeutic value of animal venom has led a pair of Columbia University data scientists to create the first catalog of known animal toxins and their physiological effects on humans.
Findings demonstrate that testosterone is a metabolic hormone as well as a sex hormone, University at Buffalo researchers say.
At this year’s MEDICA, CNOGA Medical Ltd. will be introducing its new line of non-invasive, pain-free patient vital signs monitoring TensorTip™ devices, and presenting its new Singular™ platform, a secure cloud-based ecosystem infrastructure platform as well as its new mobile application for sending results to physicians, friends and caretakers. CNOGA’s easy-to-use, portable devices are…
The University of Hawai'i Cancer Center discovery could warn patients years in advance allowing for a lifestyle change.
A panel of world experts in aging convened at Saint Louis University recommended that everyone 70 and older should have their memory and reasoning ability evaluated annually by a doctor or health care provider.
While Swatch and Rolex count the hours until their smart watches overwhelm the time market, medical informatics researchers have already been working on solutions to improve healthcare. Some demonstrated their work on a medication reminder application during the Medical Informatics Europe conference in Madrid. Report: Mélisande Rouger
Systems biology allows the mathematical visualisation through graphs and networks of complex body processes such as disease development. The aim is to improve understanding processes and triggers of diseases, so as to access and repair a damaged network. ‘We are still approaching this issue with a lot of naivety and underestimate the complexity of biological systems, and therefore of…
Researchers have successfully tested two new potential methods for diagnosing and monitoring diabetes in its standard and gestational forms. These findings, presented at the 2015 AACC Annual Meeting & Clinical Lab Expo in Atlanta, may lead to easier, timelier, and more affordable ways of identifying and treating this chronic disease.
Researchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance.
Fructose not only results in a lower level of satiety, it also stimulates the reward system in the brain to a lesser degree than glucose. This may cause excessive consumption accompanied by effects that are a risk to health, report researchers from the University of Basel in a study published in the scientific journal PLOS ONE. Various diseases have been attributed to industrial fructose in…
Painful insulin injections could become a thing of the past for the millions of Americans who suffer from diabetes, thanks to a new invention from researchers at the University of North Carolina and NC State, who have created a “smart insulin patch” that can detect increases in blood sugar levels and secrete doses of insulin into the bloodstream whenever needed.
This year’s German medical diagnostics manufacturers association (Verband der deutschen Diagnostica-Hersteller = VDGH) congress, focused on diabetes. The panel discussion that closed the evening session revealed unanimous support for the adoption of a German national diabetes plan. Report: Bettina Döbereiner
The focus of the 2015 Diabetes Congress held in Berlin this May was ‘Personalised diabetes treatment: innovative – individual – sustained’. EH reports on points aired during the supporting press briefing. Report: Bettina Döbereiner
National Institutes of Health (NIH) researchers and their colleagues have developed a "placenta-on-a-chip" to study the inner workings of the human placenta and its role in pregnancy.
Several EPFL laboratories are working on devices allowing constant analysis over as long a period as possible. The latest development is the biosensor chip, created by researchers in the Integrated Systems Laboratory working together with the Radio Frequency Integrated Circuit Group. Sandro Carrara is unveiling it today at the International Symposium on Circuits and Systems (ISCAS) in Lisbon.
The turnover in POCT diagnostics will continue to increase substantially according to participants in an ‘In Vitro Diagnostic Products’ meeting held in Toronto, Canada last October. Sponsored by the German Institute for Standardisation, the event included participation by the DIN Standards Committee Medicine (NAMed; NA 063) and the Working Committee on Point of Care Testing (POCT) (NA…
The question as to whether or not there is a point in using medical apps on private smartphones is being asked more frequently. Issues around medical diagnostics are among the key points here. We asked Prof. Dr. Dr. Norbert Gässler, Head of the Centre for Laboratory Diagnostics at the St. Bernward Hospital, Hildesheim, for competent advice. Interview: Walter Depner
Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn’t cancer usually requires a biopsy to study cells directly. Now results of a Johns Hopkins study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.
In breast cancer care each patient receives personalised, highly effective diagnosis and treatment procedures. In breast diagnostics this mainly revolves around new MRI scanning procedures that allow the quantification of biological and physiological processes on a cellular and molecular level.
Glucose testing is both a headache and an opportunity for clinical laboratories here in the United States and across the globe. It is a headache because many point-of-care and patient self-test glucose devices in wide use today lack the reliability of glucose testing performed in medical laboratories that use sophisticated diagnostic instruments.
We live in a connected world, a very different world than it was a decade ago, said Eric Topol MD. Mobile devices, wearable devices are driving a creative revolution, reducing costs of healthcare, increasing patient access to health information.
In intensive care units (ICUs) little can be automated to relieve staff pressures – with the exception of point of care testing (POCT)
Frost & Sullivan is carefully tracking the transforming global point-of-care testing (POCT) market, offering latest information on key opportunities and critical unmet needs by region
Demand is increasing for point of care (POC) diagnostic testing, particularly for tests that help foster clinical decision-making within 30 minutes or less.
The 2013 turnover expected by German in vitro diagnostics producers are significantly lower compared to last year, according to a survey of members carried out by the German Diagnostics Industry Association (VDGH) presented in January at the Diagnostica Forum in Berlin.
If technological innovation, interoperability and quality of information is your purpose, Pisa was the place to be in August.
Ensuring the safety of hospitalised patients is vital – and brought under a particularly strong focus in anaesthesiology. Launched in 2010, the Helsinki Declaration provided a further boost. Report: Holger Zorn
Anja Behringer reports on a neglected risk factor. With an aging population multimorbidity is increasingly a major challenge for hospital care. Diabetes is one of the medical conditions frequently encountered in multimorbid patients since cardiac and vascular diseases are often accompanied by dysfunctions of the blood sugar metabolism.
Obesity is physically debilitating – and costly for healthcare. Losing excess weight has positive effects on the entire metabolism and improves life expectancy. However, for patients who cannot lose their morbid, excess weight through diet, today’s surgical interventions can help towards permanent weight loss – and reduction in insulin dependency for diabetics.
Dysglycaemia is a new term in critical care that recognises the vital importance for glucose monitoring of patients in the intensive care unit (ICU). Beyond the clinical consensus over this word for grouping critically ill patients with hyperglycaemia, hypoglycaemia or high blood sugar, there is no broad agreement on how best to manage these patients. Report: John Brosky.
For three years the SWEET project, funded by the EU and the International Society for Paediatric and Adolescent Diabetes (ISPAD), has been preparing the establishment of centres of reference (CORs) for childhood diabetes. Now, the first 12 European CORs that are certified by SWEET have joined forces to promote improved cross-border cooperation in the treatment of young Type 1 and Type 2 diabetics.
UK -- Family doctors (GPs) in Norfolk are inviting patients aged over 40, with a Body Mass Index above 30 and a family history of diabetes, to take part in the Norfolk Diabetes Prevention Study (NDPS). Funded by the National Institute for Health Research, the innovative £2.2million project will run for five years at the Norfolk and Norwich University Hospital (NNUH) and will involve 10,000…
Morbid obesity is a chronic, lifelong, multifactorial, constitutional disease with negative medical, psychological, physical, social and economic side-effects. Obesity-related secondary diseases are Type 2 diabetes mellitus (T2DM), cardiovascular diseases such as hypertension or sleep apnoea. Report: Holger Zorn
Two small randomised trials published on bmj.com suggest that closed loop insulin delivery (also referred to as an artificial pancreas) may improve overnight blood glucose control and reduce the risk of nocturnal hypoglycaemia in adults with type 1 diabetes.
Medical imaging has recently advanced so rapidly that it should halt. Applying more power to computed tomography (CT) and magnetic resonance imaging (MRI) scanners is becoming too dangerous for patients and healthcare workers. Magnets for the next-generation MRIs are so powerful that they must be moved to a separate building on hospital campuses, while CT radiation levels have risen to alarming…
The International Diabetes Federation* (IDF) today launched the first ever Charter setting out the fundamental rights of more than 300 million people living with diabetes.
Metabolic syndrome, diabetes and vascular disease: What do we need to know? During ECR session this important question is addressed by vascular specialist Professor Erich Minar, Assistant Head of the Department of Angiology at the Vienna General Hospital (AKH), President of the Austrian Society of Angiology, and scientific researcher working closely with research centres in the USA.
Over the last 25 years overweight and obesity have become a global epidemic. According to WHO figures, at least 400 million adults are obese worldwide. Part of this phenomenon relates to lifestyle changes - lack of exercise, wrong eating habits - whereas genetic factors also play a role (according to twin studies, the determination of obesity is 70% nature and 30% nurture).
Much of the newly revealed variation in amputation rates in England is due to many diabetics not receiving nine key care processes, including checks on weight, blood pressure, blood glucose, cholesterol, urine and, in particular, consistent foot care checks.
During intensive care, hyperglycaemia and insulin resistance are widespread in diabetics as well as non-diabetics. However, whether the normalisation of blood glucose levels with insulin therapy improves the prognosis of such patients is still debated. Karoline Laarmann reports
Although there is still disagreement as to ‘how’, when it comes to the question of whether the glucose level affects the prognosis for intensive care patients, the answer is a definite ‘yes’. ‘
Innumerable studies (e.g. Ceriello A., et. al. 2006) have shown that postprandial hyperglycaemia is an independent risk factor for cardiovascular disease (CVD) in all populations. In diabetics, according to IDF figures, CVD is even the major cause of death (some 50 % of all diabetes fatalities) and much disability. ‘Therefore, the primary goal in diabetes treatment should be not only lowering…
7,000 people from 120 countries met in Stockholm this September to hear international experts discuss the progress, solutions and challenges of one of our greatest healthcare burdens. Prevention, self-monitoring, surgery, guidelines, economic problems, drug-safety, and co-morbidities – these are just a few of the problems associated with the care of about 55 million diabetics in Europe.
Malignant diseases rank second in mortality rates in Germany. These patients thus receive a major proportion of ambulant and hospital care, with apparent socioeconomic consequences. To optimise treatment planning, for all solid tumour entities it is mandatory to delineate or stage the primary extent of tumour invasion and spread prior to therapy as precisely as possible.
A nurse-initiated, nurse-led, and nurse-implemented study shows that nurses taking charge of diabetes care in hospital results in more patients hitting their target glucose levels. The study was led by Esther Boteach, Soroka University Medical Center Beer-Sheva, Israel, and co-workers.
Recently, the prevalence of diabetes mellitus in the Czech Republic reached 7-8% (783,321 diabetics were treated last year – 419,362 females and 363,959 males) but this figure leaps to 25-30% for diabetes related hospitalisations.
Dr Susan S Braithwaite, a visiting clinical professor in endocrinology at the Department of Medicine, University of Illinois, Chicago, specialises in the management of hyperglycaemia among hospitalised patients. Hyperglycaemia, the presence of an abnormally high concentration of glucose in the blood, is a common occurrence in adults who are hospital in-patients, especially among diabetic…
When in 1992 Dr Luigi Marzio Biasucci, head of the Sub-intensive Care Unit at the Catholic University of the Sacred Heart in Rome, Italy, published with his team the first paper on C-reactive protein (CRP) in unstable angina, few people believed in the diagnostic power of biochemical features to measure the effects or progress of disease, illness, or a condition. Today, biomarker tests are part…
A team led by UK-based researchers has found that having diabetes doubles the risk of developing a wide range of blood vessel diseases, including heart attacks and different types of stroke. The consortium, headed by Dr Nadeem Sarwar and Professor John Danesh of the University of Cambridge, analysed data from the individual records on 700,000 people, each of whom was monitored for about a decade…
The daily management of diabetes mellitus is a complex interaction between blood glucose measuring, lifestyle aspects and drug therapy. Large epidemiological trials such as UKPDS (United Kingdom Diabetes Prospective Study) have shown that an optimal blood glucose adjustment has beneficial long-term effects on type-2 diabetics’ risk of micro- and macrovascular secondary complications.
An adequate blood glucose level (4–7 mmol/l) is important not only for a diabetic’s daily well-being but also to prevent diabetes-related illnesses. HbA1c is the central marker to evaluate the success of diabetes management. But HbA1c measurement has a crucial limitation: current blood glucose fluctuations are not taken into consideration. However, the recognition of steep post-prandial blood…
Type 2 diabetics run an elevated risk of developing cancer, according to the world’s largest study on the combined risk of diabetes and cancer, conducted by scientists at the German Cancer Research Centre (DKFZ). The study focused on 24 types of cancer. The effect is most evident for liver cancer and pancreatic cancer. However, by contrast, diabetics have a significantly lower rate of prostate…
Around 75% of adult type 1 and type 2 diabetics say they believe they know what their blood sugar levels are, without testing, according to data presented at the American Diabetes Association 70th Scientific Sessions. These results are important to consider because self-monitoring with a blood glucose meter is essential for people with diabetes to obtain accurate blood glucose results that guide…
In 2009, the continuous glucose monitoring (CGM) market earned manufacturers $23.5; this is forecast to reach $52.0 million in 2016, according to a new analysis from Frost and Sullivan (F&S). For the study the markets covered by region are Benelux, Germany, France, Italy, Scandinavia, Spain and the United Kingdom.
2010 workshop in Aachen, Germany, in March, were welcomed by Professor Thomas M Deserno, head of the Medical Informatics Department at RWTH Aachen University and organiser of what turned out to be an ‘outstanding’ scientific programme.
In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate. However, a surprising discovery was made by Joslin Diabetes Center researchers in animal models of diabetes: insulin is important in regulating its own production.…
A study published this week in Lancet suggests that low A1C levels may be just as dangerous as high A1C levels in diabetes patients with respect to mortality and cardiovascular outcomes. Upon review of the study, The Endocrine Society released a statement recommending against any wholesale change in glycemic goals and strongly encourages patients to discuss these issues with their diabetes-care…
The World of Health IT Conference & Exhibition (WoHIT) 2010 will for the first time be held in conjunction with the European Union’s annual High Level eHealth Conference and is being organised by the European Commission, HIMSS Europe, the Spanish Ministry of Health and Social Policy, the Regional Government of Catalonia and Foundation TicSalut.
According to estimates up to 450 million patients will suffer from diabetes in the year 2025 (currently 250 million). In view of this, glucose monitoring is of utmost importance. Scientific studies and practical experiences with glucose monitoring at the point of care (POC) were evaluated recently during a meeting of experts in Vienna.
A child's blood pressure, body mass index, blood glucose level and other laboratory tests and simple office measures may predict the risk of developing type 2 diabetes nine and 26 years later, according to a report in the January issue of Archives of Pediatrics & Adolescent Medicine, one of, one of the JAMA/Archives journals.
Cancer imaging is one of the most promising medical fields. Hybrid technologies, such as PET/CT or future MRI/PET, are the tools radiologists and oncologists use to gain ever deeper insights into the biological characteristics of tumours. During the Medica Congress the Integrated diagnostics and therapy in oncology imaging session (Thursday 19 November) innovative tools and related developments…
Today testing of patients at the point of care (POC) accounts for 25% of all testing, and these portable assays are increasing their penetration into medical practice at rapid rate of 12% each year. Yet along with the growth comes an increasing risk of errors that adversely affect quality of clinical decision-making and patient safety.
When we organised the first Diagnostic Week in Karlsruhe, in 1969, no one could have known that this event would one day turn into the annual highlight in the world of medicine, reflected Dr Wolfgang Albath, laboratory medicine pioneer and one of the founding fathers of MEDICA the world`s largest medical trade show. Initially planned as a moving exhibition, the show has been based in…
Bayer Diabetes Care in the UK and Ireland has launched Didget, the first and only blood glucose meter for diabetic children that connects directly to Nintendo DS and DS Lite gaming systems.
Western societies are struggling to pay for their ever increasing medical budgets. In the US up to 393 billion US-$ were spent in 2005 for cardiovascular diseases alone. Based on epidemiologic studies in primary prevention it is reasonable to estimate that 30% of coronary heart disease and stroke could be prevented by 2.5 hours of brisk walking per week.
Type 1 diabetes is a life-long autoimmune disease with onset in early childhood. The diagnosis will initially turn the everyday life of children and their families topsy-turvy due to blood glucose testing, insulin injections, thorough calculation of meals, etc. It takes time before all these new and often frightening procedures become part of the daily routine of small diabetics.
The fact that child diabetics (type I) in Russia do not receive necessary and qualitative therapy was again highlighted during the 7th Russian conference 'The priority national project - Health - and the tasks of children's endocrinologists' held in Saint-Petersburg this June.
The global prevalence of Type 2 diabetes mellitus is rapidly accelerating towards a disastrous impact in just two decades.
This April, scientists, physicians, nurses, diabetes organisation heads, patients and representatives from Bayer HealthCare Diabetes Care gathered in Basel, Switzerland, for the third European Media Workshop on Diabetes. The event was hosted by Bayer HealthCare Diabetes Care, which is celebrating 40 years of innovative blood glucose monitoring.
CardioPod will be installed in pharmacies and GP surgeries across England, allowing patients easy access to an NHS Health Check carried out by a trained professional, who will give expert advice on their cardiovascular risk score and what action they can take to reduce the risk of heart disease, stroke, type II diabetes and kidney disease.
A study published by the Journal of the American Medical Association (JAMA) recently has found that those with type 2 diabetes who had a diet high in low-glycemic foods such as nuts, beans and lentils had greater improvement in glycemic control and risk factors for coronary heart disease than those on a diet with an emphasis on high-cereal fibre.
In a strategic move intended to enhance the global launch of its 'groundbreaking' diabetes monitoring device, set to help combat the 'worldwide epidemic', the US company Sensys Medical has chosen to relocate its world headquarters to the United Kingdom (UK).
A panel of experts, convened by the American Diabetes Association and the European Association for the Study of Diabetes, has issued updated treatment recommendations for type 2 diabetes, in a consensus statement published online in two journals: Diabetes Care and Diabetologia*.
Diabetes presents a special challenge for the young. Here we see how a young Swiss girl has successfully come to terms with her metabolic disorder. A true life story from Bayer HealthCare Diabetes Care (BayNews)
Approximately 31 million people in the European Union are suffering from diabetes, a devastating disease with severe consequences for patients and their families, but also for the society at large and the economic prosperity of Europe. This week EH Online will focus on innovative strategies in diabetes care and on new management systems to support physicians and patients alike. Moreover, we will…
Bayer HealthCare Diabetes Care unveiled the new CONTOUR® blood glucose meter with enhanced testing features at the 44th Annual Meeting of the European Association for the Study of Diabetes in Rome, Italy.
ESC speaker John Cleland from the University of Hull, UK, sumed up the latest treatment available for patients with diabetes mellitus and expressed his worries about side-effects and efficacy of available anti-diabetic drugs. If you want to read his ESC abstract, just click the “read more” button.
Lifestyle and risk factor results show that recommended scientific guidelines form a contrast to what is achieved in daily practice in high risk individuals in primary prevention of CVD. Together with its partners the ESC demands a comprehensive and multisdicplinary primary prevention programme involving the high-risk population, their GP's and other health professionals, a health insurance…
Unlike regular laboratory analyses, which is performed by clinical pathologists and technicians in the clinical laboratory, Point of Care Testing (POCT) are devices to perform laboratory analyses in the vicinity of the patient by the attending physician or nurses.
The probability of woman of suffering from cardiovascular diseases is often underestimated. A recent study evaluated the risk of nearly 9.000 women in the U.S. screened for heart-health risk: one in five women had a higher risk than measured by a frequently used predictor.
Diabetes fires researchers imagination: Two scientists at the University of Michigan Kellogg Eye Center developed a new screening device that gives early warnings of diabetes and its vision complications within five minutes.
This week not only one but rather two studies report about a new and independent marker that is associated with type 2 diabetes. The protein that is called fetuin-A is produced in the liver and secreted to the blood stream also indicates a higher risk of developing diabetes disease.
Bayer loves sports. Therefore it developes medical devices to work under extremes. Recently extrem-athlete and diabetic Geri Winkler conquered the Seven Summits - a group of mountains comprising the highest peaks on each of the seven continents. The blood glucose monitoring system from Bayer HealthCare is always with him.
During the 2nd European Workshop on Diabetes, hosted by Bayer HealthCare Diabetes Care, experts called for uncompromising management of diabetes.
By Professor Jean-Charles Preiser MD PhD, of the Department of General Intensive Care, University Hospital Centre, University of Liege, Belgium
For individualised radiotherapy, high-precision delineation and characterisation of the tumour is critical. If highest radiation doses are delivered in a targeted fashion, the chance of tumour cell kill increases and tumour control probability is enhanced.
Germany - Once again MEDICA 2007 drew healthcare professionals- this year around 137,000 — to attend the congress and view the enormous number of medical products demonstrated by over 4,300 exhibitors.
Presented during a symposium at Langenbeck-Virchow-Haus, in Berlin, the European CLINICIP research project aims to develop a method to improve glycaemic control during intensive care and provide a low-risk monitoring and control system that can control the metabolism of the critically ill
Born in 1891, Canadian Sir Frederick Banting was destined to become a medical scientist and Nobel Prize winner for work that led to the discovery of insulin. World Diabetes Day, held on his birthday, aims to sensitise the public - including potential patients - to this condition. Worldwide, around 245 million people suffer Diabetes mellitus. With 5.3 million of them in Germany, the country's…
The results of the blood pressure lowering arm of the ADVANCE (Action in Diabetes and Vascular Disease) study, the largest ever trial conducted in people with type 2 diabetes, were recently reported in the Lancet.
Professor Oliver Schnell, of the Diabetes Research Institute, Munich, reports on discussions and findings of a panel of diabetes experts who met this summer in Switzerland
Researchers from the Robert Gordon University in Aberdeen, UK, presented a study at The British Pharmaceutical Conference, held from 10th to 12th September, 2007, at Manchester Central, showing that a chemical coating is able to encapsulate and protect insulin against enzymes that usually break down the hormone in the gastrointestinal tract.
San Diego, California - 20,000 international physicians, scientists and other visitors travelled to the Annual Meeting & Clinical Lab Expo of the American Association for Clinical Chemistry (AACC) in July, and 750 exhibitors emphasised the increasing importance of this gathering
Phosphagenics' TPM uses natural dermal transport mechanisms to deliver a dose of medication through the skin into the bloodstream. Now a Phase 1b transdermal insulin trial was completed successfully.
Preliminary findings from the largest-ever study of treatments for diabetes provide no evidence that intensive treatment to lower blood glucose (sugar) increases risk of death.
By Stefan G Ruehm MD PhD, Associate Professor of Radiology, at the David Geffen School of Medicine, UCLA, California
The recent 26th International Symposium of Intensive Care and Emergency Medicine - the largest annual meeting of its kind - attracted around 5,000 participants, who travelled to Brussels from over 80 countries.
The 26th International Symposium of Intensive Care and Emergency Medicine in Brussels: A resumee.
UK - A hand-sized, electronic peak flow meter, which measures lung capacity and can be connected to a PDA mobile handset is being tested for use by asthma sufferers.