Glucose stabilisation right from the beginning

Image source: Greiner Bio-One

Product of the Month

Glucose stabilisation right from the beginning

Effective glycolysis inhibition for precise determination of the in vivo blood sugar content with the Vacuette® FC Mix Tube of Greiner Bio-One.

Plasma glucose levels are essential for the evaluation of diabetes mellitus as well as gestational diabetes. Diabetes mellitus is one of the most common metabolic disorders in the world. The breakdown of glucose (glycolysis) in venous blood samples is of great significance in pre-analytics, particularly in relation to the diagnosis of diabetes mellitus and gestational diabetes.

Photo

Image source: Greiner Bio-One

Greiner Bio-One has a solution in the form of the Vacuette® FC Mix Tube. This special additive mixture not only reduces the pH value and blocks the pH-dependent enzymes that would be active in the initial stage of the glycolysis cascade. The Vacuette® FC Mix Tube from Greiner Bio-One can also stabilize the sample immediately after collection for up to 48 hours.

The time from collection until separation of plasma and cells, temperature as well as cell count strongly affect glucose levels, possibly leading to false low results. Unfortunately, fluoride alone is not able to stabilize the real in-vivo glucose level completely. 

Vacuette® FC Mix Tubes are citrated and therefore can help to prevent the initial loss of glucose within the first few hours from collection until fluoride shows its effect. Buffered Na2EDTA, citric acid, sodium citrate and sodium fluoride are used to decrease the pH and block the pH dependent enzymes, which would be active in the initial stage of the glycolysis cascade.

Photo

Image source: Greiner Bio-One

The shatter-proof tube is made of polyethylene terephthalate (PET). PET is important for the stability of the vacuum. The safety cap is particularly easy to open and allows for hygienic working. The transparent plastic label provides an optimum view of the tube contents. 

The powder additive in the Vacuette® FC Mix Tube has no dilution effect. There is no need to take a conversion factor into consideration. Inverting ten times ensures that the tube additive is completely dissolved and well mixed with the sample.

Should the tubes be stored longer than 24 hours at room temperature, samples should be centrifuged after blood collection. Centrifuged aliquots from FC Mix Tubes can be stored for up to 48 hours at room temperature. Tubes should be centrifuged within 20 minutes after blood collection. Cooling of the samples is also suitable for 48 hours glucose stabilization.


More information on the Greiner Bio-One website www.gbo.com.

01.03.2021

More on the subject:More on companies:
Read all latest stories

Related articles

Photo

Product of the Month

For your most precious samples: MiniCollect® Capillary Blood Collection System

MiniCollect® offers a gentle way to collect small blood samples for a wide range of analyses. The capillary blood sample is becoming increasingly popular as specimen material due to its simpler and…

Photo

The gentle touch

Vacuette® Evoprotect Safety Blood Collection Set: the next evolution of safety

Greiner Bio-One presents the Vacuette® Evoprotect Safety Blood Collection Set - the ideal choice for venous blood collection and short-term infusion of intervenous fluids.

Photo

Product of the Month

The gentle touch

The brand-new Vacuette® Evoprotect Safety Blood Collection Set is the next evolution of safety.

Related products

Greiner – Saliva Collection System

Rapid Testing

Greiner – Saliva Collection System

Greiner Bio-One
Greiner – Vacuette CAT Serum Fast Tube

Clinical Chemistry

Greiner – Vacuette CAT Serum Fast Tube

Greiner Bio-One
Greiner – Vacuette Coagulation Tube

Hemostaseology

Greiner – Vacuette Coagulation Tube

Greiner Bio-One
Greiner – Vacuette EDTA Tube

Blood Cell Counter

Greiner – Vacuette EDTA Tube

Greiner Bio-One
Greiner – VACUETTE FC Mix tube

Blood Glucose

Greiner – VACUETTE FC Mix tube

Greiner Bio-One
Subscribe to Newsletter