Search for: "trial" - 250 articles found

Article • Risk stratification initiatives in Europe and UK

The future of breast imaging: a date with density

About 60% women in Europe enrolled in a national breast cancer screening programme who have a screening mammogram can feel reasonably confident that radiologists will be able to diagnose early-stage breast cancer. But what about the 30% categorised as having dense breasts, and the 10% who have extremely dense breasts? At the 2025 SBI (Society of Breast Imaging) Breast Imaging Symposium held in…

News • Multi-lens ultrasound arrays

4D blood flow imaging of whole organs

3D + time: a new 4D ultrasound imaging technique could both improve our understanding of the circulatory system and facilitate the diagnosis of certain blood circulation-related diseases.

News • Link between Covid, flu, HIV and CVD

Viral infections may increase the risk of cardiovascular disease

After a bout of influenza or Covid, the risk of heart attack or stroke may rise dramatically, and chronic infections may increase the long-term risk of serious cardiovascular disease events.

Article • Reshaping GI cancer care

Pathologists at the heart of precision oncology

Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…

News • Neurostimulation system

New implant partially restores vision in AMD patients

A novel subretinal implant could help patients with age-related macular degeneration (AMD) partially restore eyesight, a new study shows. Participants recovered their ability to read letters, numbers and words.

News • AI in cancer care

New 3-tier framework sets safety standards for LLMs in oncology

Underscoring the growing role of large language models (LLM) in cancer care, ESMO released the first structured set of recommendations to bring AI language models into oncology safely and effectively.

Automation

AIRAQc

Our AI-powered pre-analytical quality-control platform that identifies and quantifies artifacts in WSIs promptly flagging artifacts like air bubbles, tissue folds, knife lines or out of focus to ensure consistent image quality.This in turn reduces the turnaround time and improves downstream accuracy. This solution is built for oncology diagnostics and clinical trials, our solutions deliver…

Automation

AIRAQc

News • Proteins for personalized treatments

Tracking Duchenne muscular dystrophy with blood biomarkers

Newly discovered blood biomarkers may offer new options to track Duchenne muscular dystrophy (DMD) in a less invasive way than physical tests or biopsies. This could support more tailored treatments.

News • Long-term subcutaneous EEG

Breaking new ground to advance seizure monitoring and epilepsy diagnosis

Traditional diagnostic methods for epilepsy face significant limitations. A new clinical trial explores the potential of advanced brain monitoring to improve diagnosis and management of the condition.

News • Radiation-induced cognitive decline

New approach to protect the brain during radiation therapy

Researchers identified a targeted way to protect the brain from harmful side effects of cranial radiation therapy, potentially preserving the quality of life for millions of brain cancer survivors.

News • Focus on Helicobacter pylori

Towards a vaccine against ulcers, stomach cancer

Scientists are on the way to finding a vaccine to fight off Helicobacter pylori - a bacterium found in over 60% of people - possibly preventing stomach ulcers and lowering the risk for stomach cancer.

News • Study explores clinical potential of WGS

Whole genome sequencing could help 15,000 breast cancer patients per year, study finds

Breast cancer claims around 670.000 lives each year. Now, researchers propose that whole genome sequencing (WGS) could help many patients find better treatments or match them with clinical trials.

News • Precision Oncology Ireland (POI)

Ireland’s largest ever cancer research programme enters next phase

Precision Oncology Ireland (POI), a €28M cancer research programme uniting universities, charities and industry to develop tailored diagnostic and therapeutic solutions, has now entered phase 2.

News • Unified framework

Establishing a global standard in sepsis and critical care

The heterogeneity of critical illnesses like sepsis, ARDS, and trauma creates immense challenges. A new, unified way to classify patients aims to improve treatment.

Article • Personalizing stroke care

Advancing genomic medicine from promise to practice with digital technology

Stroke patients in four NHS hospitals are now receiving genetic tests that determine whether a commonly prescribed drug will work for them – a breakthrough that could transform treatment for millions. Digital approaches are spearheading a drive to help make genomic medicine part of everyday care. The role of digital tools was a central theme at the HETT (Healthcare Excellence Through…

News • Peripheral immune tolerance

Immune system researchers receive Nobel Prize 2025 in Medicine

The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.

News • AML targetable immune escape mechanism

How leukemia cells trick the immune system

Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.

News • Call for more informed decision

Hormone replacement therapy after breast cancer: a risk worth taking?

Breast cancer survivors are often discouraged from undergoing hormone replacement therapy (HRT) to alleviate menopause symptoms. Now, new research paints a more differentiated picture.

News • How much does it hurt?

‘Monetizing’ pain for more accurate assessments

Asking people how much money they would accept to experience pain again can provide a more accurate and comparable measure of pain levels than the familiar 1–10 scale, according to new research.

News • Remote paediatric care

Asthma in children: study shows benefits of at-home monitoring

Children with asthma using at-home monitoring are around half as likely to visit the ED or be hospitalised, compared to those only receiving care from their medical team, new research shows.

News • Estimation of nodule malignancy risk

Lung cancer screening: AI to reduce false positives

Misinterpreting the malignancy risk of lung nodules often results in high false-positive rates, unnecessary follow-ups, increased patient anxiety and healthcare costs. A new study suggests that AI can fix this.

News • Response to changes in pH levels

‘Artificial cartilage’ releases drugs to counter arthritis flare-ups

A squishy new ‘artificial cartilage’ material could improve arthritis treatments by releasing anti-inflammatory drugs in response to a flare-up.

News • EGFR-mutated non-small cell lung cancer

NSCLC: Surgical combination therapy may prolong disease control

In metastatic EGFR-mutated non-small cell lung cancer (NSCLC), targeting residual disease through surgery can extend the benefits of EGFR TKI therapy beyond standard monotherapy, a new study finds.

News • In situ printing of biodegradable implants

Fixing bone fractures with a glue gun? Not as crazy as it sounds

Historically, implants to repair bone fractures have been made of metal, donor bone, or 3D-printed material. Now, scientists propose an in-situ printing approach - using a modified glue gun.

News • Focus on health-related quality of life

Pushing for a more patient-centered approach to advanced cancer care

Currently, cancer treatment evaluation focuses heavily on survival outcomes, but doesn't adequately consider how treatments affect quality of life. A new policy review aims to change this.

News • Clarithromycin versus endoscopy

Sinusitis: Study favors surgery over antibiotics

Surgery or antibiotics? For the first time, a major clinical trial compared treatment options for chronic rhinosinusitis (CRS), or sinusitis – clearly favoring the surgical approach.

Roxana Mehran, MD

Prestigious honor for contributions to cardiovascular medicine

The European Society of Cardiology (ESC) has awarded Roxana Mehran, MD, from Mount Sinai, with its top honor, the “ESC Gold Medal”, during a special ceremony at the ESC Congress in Madrid.

News • Pharmaceutical Automation and Digitalisation Congress

AI in Action: Transforming Pharma Industry with AUTOMA+ 2025

The Pharmaceutical Automation and Digitalisation Congress (AUTOMA+) 2025 is a hub for decision-makers and digital innovators for exchanging insights on the integration of AI within pharma operations. To bring on the networking discussions, the Congress is held in Vösendorf, Austria on November 24-25.

News • Prediction of treatment sensitivity

Personalising prostate cancer treatment through molecular testing

A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.

News • Implicit information

In-depth AI microbiome analysis reveals colorectal cancer

Scientists developed an AI-based approach to diagnose colorectal cancer from different microbial subgroups in the gut microbiota – a non-invasive and low-cost alternative to colonoscopy screening.

News • Evidence-generated sockets

Data-driven designs to improve prosthetic legs

Researchers have developed a new, data-driven way of fitting prosthetic legs which could lead to better fitting prosthetics, in less time and at a lower cost.

News • SEBS material safety

New artificial heart valve passes long-term test in animals

An artificial heart valve made from SEBS, a new type of highly durable and biocompatible plastic, could be a step closer to use in humans, following a successful long-term safety test in animals.

News • Breast cancer screening

Mammography: Hybrid reading to overcome AI overconfidence

Mammography image interpretation AI models are unreliable – but so are human readers. A new hybrid strategy could reduce radiologist workload by 38% without compromising diagnostic efficacy.

News • Study explores drug misinformation

Breastfeeding and medication: safety advice often unfounded

Breastfeeding women often choose not to take their medications because they worry about their baby; or stop breastfeeding because of their medicines. However, new research suggests that this is often unnecessary.

News • Adenoma detection rate

Using AI support makes endoscopists lose skills, study finds

AI tools for adenoma polyp detection are designed to help increase the accuracy of colonoscopies. However, a new study finds that using AI may lead to loss of detection skills in health professionals.

News • Review explores bacterial impact

Vaginal microbiome holds untapped potential for women's health

The vaginal microbiome is a largely overlooked area of medicine that could dramatically improve outcomes for common infections, infertility and even cancer for millions of women, a new review finds.

News • Microsatellite instability

Predicting tumor MSI status for precision cancer treatments

Microsatellite instability-high (MSI-H) tumors are associated with better clinical outcomes. A novel AI model for accurate MSI prediction could help battle gastric and colorectal cancers.

News • Cardiovascular benefits and risks of CPAP

Sleep apnoea treatment improves heart health for some (but makes it worse for others)

A treatment commonly used for obstructive sleep apnoea (OSA), lowers the risk of serious cardiovascular events in some patients but not others, according to new research.

Article • Blood-based biomarkers under scrutiny

BBB testing for universal Alzheimer’s screening? It’s complicated

Do laboratory tests using blood-based biomarkers (BBB) represent the next type of universally recommended screening tests for Alzheimer's disease (AD)? Experts curb the high expectations for this type of diagnostic tool.

News • Predictive phenotypes

Ovarian cancer: new insights into immune landscapes

Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.

News • Rapid exosome isolation and detection

Researchers develop at-home skin patch test for melanoma

Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.

News • Proportional assist ventilation (PAV+)

Personalized ventilation to help ICU patients breathe

A new ventilation mode called proportional assist ventilation (PAV+) could improve outcomes for patients in the intensive care unit (ICU) who require help breathing, a new study finds.

News • Prediction of regurgitant valvular heart diseases

AI identifies hidden heart valve defects from a patient’s ECG

A new AI tool has been shown to accurately predict who would go on to develop leaks in the heart valves – conditions known as regurgitant valvular heart diseases, at a very early stage from an ECG.

News • The nose knows

Dogs successfully trained to sniff out Parkinson's disease

Two dogs have been trained to distinguish between sebum swabs from people with and without Parkinson’s disease. This is especially relevant, as a definitive diagnostic test remains elusive.

News • Under-the-skin glucagon reservoir

Diabetes: emergency implant to stave off hypoglycemia

An implantable device could save diabetes patients from life-threatening hypoglycemia. Remaining under the skin, it can be triggered to release glucagon when blood sugar levels get too low.

News • Autonomous system trained on surgical videos

Robot performs realistic surgery without human help

A potentially transformative advancement in surgical robotics: A robot trained on videos of surgeries successfully performed a lengthy phase of a gallbladder removal without human help.

News • Mechanical forces guide axon growth

Magnet-pulling brain cells to treat Parkinson's

In an unconventional, but promising approach to treat neurological conditions like Parkinson, researchers use nanoscale magnetic pull to rebuild lost conncections between brain cells.

News • Study shows benefits of earlier FIT

Colorectal cancer screening: 40 is the new 50

Starting fecal immunochemical testing (FIT) early significantly reduces both the incidence and mortality of colorectal cancer. These results of a new study support earlier screening.

News • Emergency hospitalisation driver

Polypharmacy: hidden risks for older patients

Too many medicines, too many hospital visits: Inappropriate polypharmacy is a major driver of emergency hospital admissions among adults aged 65 and over, according to a new study.

News • Tumor microenvironment in nasopharyngeal carcinoma

Towards more personalized treatment of nose cancer

Molecular profiling of over 1,000 nasopharyngeal cancer (NPC) tumours reveals distinct differences in tumour microenvironment of locoregionally advanced NPC, supporting personalised treatment.

News • Dual targeting radioligand

“Smart missile” radiopharmaceutical shows promise against multiple cancers

New research makes a strong case for a new dual-targeting radiopharmaceutical, designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy.

Article • Diagnostic and care support

Atrial fibrillation: digital technology to the rescue?

Machine learning (ML) for personalised care, large language models for empathy training of cardiologists, wearable sensor data for better screening, and more: Digital technologies hold great potential to improve diagnosis and treatment of patients with atrial fibrillation (AF). At the ESC 2024 cardiology congress in London, four experts explored the benefits of new solutions and pointed out…

Article • New technologies, old limitations?

Robot-assisted surgery in Europe: high tech between scalpel and legislation

The use of surgical robots offers a wide range of possibilities, but in Europe the technology is often unable to reach its full potential. Dr. med. Christoph Wandhöfer explains why.

News • Fluorescent probe

New visualisation tool targets breast cancer dissemination

In a new study, researchers have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells, to uncover a new therapeutic possibility for limiting breast cancer spread.

News • Precision medicine

Melanoma: with 43,000 data points to tailored treatments

Using nine different molecular biological technologies, researchers were able to precisely measure the properties of a melanoma tumor in four weeks and enable a precise treatment decision.

News • Genetic signature mapping

Diagnosing Parkinson’s from a blood sample

In a world first, researchers have identified a set of biomarkers that could someday make it easy to spot Parkinson's disease in a patient’s blood sample.

News • Early detection of life-threatening conditions

Newborn immune profiling to improve neonatal care

Newborns, especially those born prematurely, are vulnerable to conditions such as sepsis. A new device profiles an infant’s immune function from a single drop of blood to improve neonatal care.

News • Appeal for tailored care approaches

Breast cancer: Study reveals ethnic differences in development and outcomes

When it comes to breast cancer, ethnic differences matter, putting some women at a significantly higher risk, a new study finds. Genetic ancestry should therefore be considered as a risk factor.

News • Diagnostic assistance

Pancreatic cancer: clinical deployment of AI system for early detection

Survival rates for pancreatic cancer rise drastically the earlier it is detected, but early-stage tumors are notoriously difficult to spot. A new AI-powered diagnostic system is set to improve this.

News • Study on diagnostic accuracy of AB-MRI

Abbreviated MRI effectively detects cancer in dense breasts

Diagnosing breast cancer in women with extremely dense breasts often comes down to MRI, but the scans take long and are expensive. Research confirms that shorter protocols also yield accurate results.

News • Deep learning-based assessment

AI ‘Sybil’ predicts lung cancer risk from single LDCT scan

A deep learning model was able to predict future lung cancer risk from a single low-dose chest CT (LDCT) scan, according to new research published at the ATS 2025 International Conference.

News • Boron neutron capture therapy

BNCT: From clinical trial to cancer treatment

With the introduction of boron neutron capture therapy (BNCT), Helsinki University Hospital offers a new radiation therapy method that can destroy cancer cells while sparing the surrounding tissue.

Dr Jakob Kirkegård

Leveraging the power of data to improve pancreatic cancer treatment

Jakob Kirkegård is a physician, associate professor, and now also a doctor at Aarhus University's Department of Clinical Medicine and Aarhus University Hospital. He has just obtained his doctoral degree in the surgical treatment of pancreatic cancer – one of the most deadly forms of cancer.

News • New organ-preserving options explored

Five major advances in anal and rectal cancer treatment with radiotherapy

From organ-preserving treatments to chemo-immunotherapy combinations: five studies presented at ESTRO 2025 showcase how radiotherapy is reshaping the treatment landscape for anal and rectal cancer.

News • From RRMS to SPMS

Multiple sclerosis: AI detects crucial transition point

Multiple sclerosis often transitions from a relapsing-remitting to secondary progressive form, which requires different treatment. Now, an AI model can determine this change with 90% certainty.

News • Reactions to noise as biomarkers

Tinnitus diagnosis via AI-powered face scan

Pupil dilation and involuntary facial movements could provide a window into diagnosing tinnitus. A new method uses AI to detect minuscule reactions to various sounds and noises.

News • Combining spatial transcriptomics, pseudotime and machine learning

More precise than PSA: New biomarkers for prostate cancer found in urine

Using AI and extensive analyses of gene activity in tumours, researchers have found new, precise biomarkers to diagnose prostate cancer at an early stage through a simple urine sample.

News • Electron-sink-enhanced nanoshells

A label-free method for trace detection of cancer

A new approach enables the detection of even trace amounts of cancer cells. The method leverages SERS for signal amplification, eliminating the need for fluorescent dyes.

News • Hybrid imaging

PET/MR update for added value in theranostics

Bringing diagnostics and therapy closer together - that is the basic concept behind theranostics. Through further development of its PET/MR scanners, Siemens Healthineers aims to advance this approach. Andreas Schneck, Head of the MRI Division at Siemens Healthineers, talks about the new system, which was also presented at the European Congress of Radiology (ECR) in Vienna, and its advantages in…

Dr Ari Melnick

A new chapter in leukaemia and hematologic disease research

Dr Ari Melnick has been appointed the new Director of the Josep Carreras Leukaemia Research Institute by the Board of Trustees. The institute specialises in biomedical research and precision medicine in the field of leukaemia and other hematologic malignancies.

News • Carotid artery stenosis

After stroke: new approach favors medication over surgery

A risky carotid artery operation may no longer be necessary for patients who suffer a stroke due to carotid artery narrowing, research suggests. Instead, medication-only treatment may also be viable.

News • Synthetic fibrosis distributions

AI generates ‘scarred hearts’ for better cardiac treatments

Researchers have developed an AI tool that creates synthetic yet medically accurate models of fibrotic heart tissue (heart scarring), aiding treatment planning for atrial fibrillation (AF) patients.

News • Affordable, wearable solution

Vibrating glove to help treat Parkinson's disease

Using vibrations to help people living with Parkinson's disease regain motor control: Engineering students have created a special glove that aims to reduce the symptoms of the condition.

News • Brain MRI analysis

AI tool tracks effectiveness of multiple sclerosis treatments

A new AI tool can extract key information from brain MRI scans of multiple sclerosis (MS) patients. This could be used to improve disease and treatment response monitoring.

News • Swedish national initiative

Precision omics to boost data-driven medicine

The new national Precision Omics Initiative Sweden (PROMISE) aims to generate and integrate extensive molecular data to create a model for precision medicine implementation for Sweden.

News • Trial on selective surgery omission

Invasive breast cancer: surgery not always necessary, study finds

Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant chemotherapy and standard radiotherapy, new research finds.

News • Arrhythmia prediction

Using AI to prevent sudden cardiac death

A network of artificial neurons imitating the human brain could help identify patients at risk of a serious arrhythmia from an ECG and avoid many cases of sudden cardiac death, a new study suggests.

News • Landmark surgery trial

Gastric bypass, sleeve or band? Study weighs up surgical options for severe obesity

Severe obesity comes with serious health risks, which can be reduced with metabolic and bariatric surgery. Now, a landmark study reveals which operation is most effective or cost-effective.

News • Potential for patients with knee pain

Artificial lateral meniscus makes clinical debut

Researchers have designed an artificial lateral (outer) meniscus that could help patients with chronic knee pain. The first patients have already undergone surgery and begun rehabilitation.

News • Threat to medical device availability

Cardiologists call for urgent MDR revision

While the Medical Device Regulation was designed to enhance safety and quality, its complexity and certification costs threaten the availability of vital devices. Cardiologists urge for revision.

News • Alternative to MRI-guided biopsy

Micro-ultrasound to speed up prostate cancer diagnosis

To diagnose prostate cancer, an MRI-guided biopsy is often performed. Now, a study shows that micro-ultrasound is just as effective, cheaper and easier to use. This could help free up MRI capacities.

Video • Oloid-shaped magnet-driven probe

Virtual biopsy: tiny robot wobbles its way through the gut

Engineers developed a robotic probe that can generate high-resolution 3D ultrasound images from deep inside the gastrointestinal tract. The robot reaches its target with a unique kind of movement.

News • Nuclear medicine

Lung fibrosis: radiopharmaceutical improves diagnosis and monitoring

Nuclear medicine specialists have successfully used the radiopharmaceutical Ga-68-Trivehexin from Trimt to accurately diagnose patients with pulmonary fibrosis and concurrent lung cancer.

News • Pilot study on wearables

Telemonitoring t-shirt allows patients to return home earlier after urological surgery

Could a t-shirt with sensors reduce the time patients need to stay in hospital after a urological surgery? A recent pilot study suggests it might.

Article • Freezing cancer cells

Cryoablation: A treatment option for low-risk early-stage breast cancer

Cryoablation, the destruction of malignant cancer cells by freezing them, is increasingly becoming an alternative to having conventional lumpectomy for patients diagnosed with early-stage, localised, low-risk breast cancer. Findings from numerous recent clinical trials show that cancer recurrence rates are very low and are comparable to breast conservation surgery (BCS).

News • High-channel prostheses

One step closer to visual implants

Electrodes implanted directly onto the brain’s visual cortex could eventually restore a rudimentary form of vision to people suffering from blindness worldwide, new research suggests.

News • Plasma vs. whole blood resuscitation

Trauma surgeons propose ‘precision transfusion’ approach

Giving separated blood plasma improves outcomes in patients with traumatic brain injury (TBI) or shock, whereas unseparated or “whole” blood may be best for patients with traumatic bleeding.

News • Neuroprosthesis research

Restoring movement to paralysis patients with robotics and spinal stimulation

A new system that seamlessly integrates an implanted spinal cord neuroprosthesis with rehabilitation robotics delivers well-timed electrical pulses to enhance mobility and foster long-term recovery.

News • Circulating tumor DNA analysis

Liquid biopsy helps reduce chemotherapy in colon cancer patients

For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.

News • LDCT rule-out

AI shows potential for workload reduction in lung cancer screening

A new study reveals that AI can accurately rule out negative low-dose CT (LDCT) scans, potentially reducing the workload of radiologists in lung cancer screening by up to 79%.

Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…

Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

News • From the heart to the mind

'Dorian Gray' to uncover link between CVD and MCI

Around one third of people with cardiovascular disease (CVD) also have mild cognitive impairment (MCI), yet the condition is often undiagnosed. A new project aims to untangle this MCI-CVD connection.

Article • Congress preview

ECR 2025: Welcome to Planet Radiology!

Science, sustainability, and society – these are the three cornerstones of this year’s European Congress of Radiology (ECR) in Vienna, Austria. Following the motto “Planet Radiology”, the congress focuses on the environmental impact of diagnostic imaging while exploring ways to advance equitable global healthcare access.

News • Potential for recovery

PET tracer offers new insights into spinal cord injuries

By detecting nerve connections in the injured spinal cord, a newly developed radiotracer could help diagnose injuries more precisely, monitor recovery, and evaluate therapy effectiveness.

News • Reduced need for follow-up treatments

Crohn's disease: Mesenteric-based surgery shows promise

Crohn’s disease is incurable, with high rates of recurrence. A new approach, involving surgical removal of the mesentery, dramatically reduces the possibility that follow-up surgery will be needed.

News • Amyotrophic lateral sclerosis research

AML: sleep problems identified as early warning sign

Promising insights into amyotrophic lateral sclerosis (ALS): New research links characteristic symptoms of the disease, such as motor impairment and respiratory issues, to sleep disorders.

News • Alternative to diagnostic brain imaging

Exploring the potential of blood tests for dementia diagnosis

Molecular changes associated with brain inflammation and dementia can be detected in the blood. Researchers want to use this to establish blood tests as an alternative to more costly brain scans.

News • Millimeter-wave sensor technology

Non-contact breathing monitoring for X-ray and CT imaging

To improve breathing monitoring during radiotherapy, researchers have developed a millimeter-wave sensor capable of non-invasively visualizing respiratory movement during X-ray and CT examinations.

News • Micro Immune Response On chip (MIRO)

Replicating tumours to assess cancer immunotherapy efficacy

Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.

News • Mechanical vs medication approach

Stroke: thrombectomy and thrombolysis equally effective in preventing disability

While thrombectomy to remove blood clots after a stroke is increasingly performed, new research suggests that it may not be needed in all cases.

News • PROLIFERATE_AI evaluates RAPIDx AI

AI keeps an eye on health AI

It takes one to know one: Researchers have developed an AI-based evaluation tool to assess how well clinical AI tools perform in the hospital.

News • Trial results surpass expectations

AI enhances breast cancer screening performance

AI-supported screening for breast cancer can detect more cancer cases compared with traditional screening, and find more invasive cancers at an early stage, results from the MASAI trial indicate.

News • Exploring the neurovascular unit (NVU)

Promising new approach to detecting Alzheimer's

Research suggests a new approach to detecting Alzheimer’s disease: changes in brain oxygenation dynamics and neuronal function contribute to the neurodegeneration.

News • Promising imaging agents

Alzheimer's disease: New radiotracers for better detection

Two new radiotracers outperform the current FDA-approved tracer for detecting Alzheimer's disease, showing higher binding to affected tissue and greater selectivity for identifying tau tangles.

News • Structural research

Researchers use “hallmarks of cancer” to understand tumour growth

“What is a tumour?” Researchers explore tumour architecture as a valuable source of information to understand tumour dynamics and predict its sensitivity to anticancer drugs.

Extensive testing demonstrates the efficiency of the Pentax Medical PlasmaTyphoon™+

Patient safety is at the heart of every medical advancement, and technologies like endoscopes have been pivotal in transforming surgery by enabling minimally invasive procedures. This evolution has led to safer operations, reduced complications, and improved patient outcomes. However, these advancements depend on rigorous hygiene protocols for reusable medical equipment.

News • Coronary computed tomography angiography

CCTA routine scans prevent thousands of heart attacks, study finds

Coronary computed tomography angiography (CCTA) 3D imaging of the heart greatly contributes to preventing heart attacks, compared to standard tests, a new study finds.

News • Oncological gynecology

Cervical cancer: HPV vaccine to get rid of precancerous lesions

Infection with the human papillomavirus (HPV) is the most common cause for cervical cancers. Now, researchers have developed a promising therapeutic vaccine against precancerous lesions.

News • From CT to prototype

Designing 3D printed surgical guides for cardiovascular surgeries

Patient-specific 3D printed surgical guides could provide a clear visual aid that helps cardiac surgeons locate key treatment areas on the heart, such as the optimal location to build the bypass vein.

Video • Miniaturisation milestone

Sub-millimetre robot for interventional diagnosis and treatment

Less than a millimetre: the world's smallest biomedical robot is designed for imaging, sampling, drug delivery, and laser ablation. The developers highlight potential new clinical applications.

News • From core to penumbra

‘Stroke-on-a-chip’ model to replace animal testing

Researchers are developing a new in vitro model for stroke. If successful, this could significantly reduce reliance on animal models in stroke research by up to 1,000 animals each year across the UK.

News • mpMRI vs TURBT

Bladder cancer: MRI scanning and biopsy as shortcut to correct treatment

Patients with a common aggressive type of bladder cancer could get correct treatment significantly quicker as new research suggests that initial MRI imaging and biopsy could reduce wait times.

News • Outbreak response study

Hepatitis E vaccination: 2 out of 3 doses still effective in an epidemic

The vaccine to protect against Hepatitis E is given in a 3-dose regimen. However, in an epidemic setting, two doses have also proven effective, a new study shows.

News • Catheter-based approach

New method aims to "steam away" prostate cancer

Steam eliminates wrinkles and germs, but can it destroy cancer cells too? A multisite clinical trial explores the potential of a water vapor system using steam to kill prostate cancer cells.

News • Long-wavelength exposure

Red light linked to lowered blood clot risk

Light can change biological processes and affect health. For example, new research finds that red light can lower rates of blood clots that can cause heart attacks, lung damage and strokes.

News • Checkpoint inhibitor immunotherapy efficacy

AI tool uses routine blood tests to predict cancer immunotherapy response

Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.

News • Bacterial-induced host metabolic shift

How Salmonella can lead to colon cancer (and how it may be stopped)

Infections with Salmonella can increase the risk of colon cancer. New research sheds light on how this bacterium can cause this. The findings provide new leads for new treatments.

Article • Keynote on integrated diagnostics

Predicting – and shaping – the future of modern pathology

Complex diseases could require complex biomarkers for accurate diagnosis in the years ahead, according to a leading pathologist. In a keynote address to the 36th European Congress of Pathology in Florence, Italy, Professor Manuel Salto-Tellez highlighted this as one of the major future challenges for the discipline. However, he also believes pathologists will sit at the core of modern medicine.

News • PET compound

New radiotracer lights up aggressive cancer tumours

A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.

News • DTI reveals intraepithelial neoplasia

Detecting pre-malignant pancreatic lesions with diffusion tensor MRI

In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.

News • Human papillomavirus infection

Cervical cancer: improved screening through HPV risk groups

Analyses of self-tests for human papillomavirus (HPV) can be used to divide HPV-positive women into three risk groups, according to a new study. This could enhance cervical cancer screening.

News • New approach to combat treatment resistance

How chemotherapy affects ovarian cancer tumours

Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.

News • Striking structural reorganisation

Pregnancy and nursing massively changes up mothers' intestines

When women are pregnant and nurse their babies, their bodies change to ensure the health of both mother and child. Researchers now surprisingly find that the intestine also changes completely.

News • Hyperpolarised carbon-13 imaging

Metabolic MRI imaging distinguishes ovarian cancer subtypes

A new MRI-based imaging technique predicts the response of ovarian cancer tumours to treatment, and rapidly reveals how well treatment is working, in patient-derived cell models.

News • Functional connectivity imaging

fMRI brain scan predicts effectiveness of spinal cord surgery

Spinal cord stimulation is performed for patients with chronic pain. However, for some patients, the procedure is not effective. A new method involving fMRI could help predict success.

A technological solution for preventing device-detected subclinical AF?

As pharmacological options for subclinical Atrial Fibrillation and atrial high-rate episodes continue to run into challenges, new research suggests more physiological pacing solutions can help reduce risks of progression to clinical AF.

Article • Experts explore the future of CSP, CRT, ICD

Implantable cardiac devices: which techniques are ready for prime time?

Opposing views on new implantable cardiac devices were aired in a Great Debate session at the European Society of Cardiology’s annual 2024 congress in London. Experts discussed emerging techniques and technologies and debated whether they are actually ready for clinical application. At the core of the session was the issue of whether conduction system pacing (CSP) should replace cardiac…

Article • Artificial intelligence meets internal medicine

Medical AI: Enter ‘dea ex machina’

In the world of theatre, the ‘deus ex machina’, the god from the machine, is a dramaturgical trick to resolve seemingly unsolvable conflicts. Can artificial intelligence (AI) also be such a universal problem solver for internal medicine? At the Annual Congress of the German Society of Internal Medicine (DGIM), Dr Isabella Wiest explored the potential – and limitations – of AI helpers.

News • Tackling bacterial infections

Personalised phage therapy as alternative to antibiotics

The current rise in antibiotic resistance is once again sparking interest in phage therapy. Now, scientists developed a new tool that recommends the best possible phage cocktail for a given patient.

Article • Generative AI

Large language models: enabler or eroder of cardiovascular care?

Large language models (LLMs) have potential in healthcare settings to help support both patients and clinicians. Cardiologist Dr Robert van der Boon believes they could have several applications, including patient communication and education, clinical decision support and administrative tasks. Delegates to ESC 2024 in London heard roles explored for LLMs in areas of clinical decision-making,…

News • New therapy approach for brain tumors

Attacking glioblastoma from multiple angles

A new approach to fight glioblastoma: Swiss researchers have now developed an immunotherapy that not only attacks the brain tumor—it also turns its microenvironment against it.

News • Research on bearing materials

Hip replacement: Study shows which implants are built to last

New research has identified hip implant materials with the lowest risk of needing revision, helping hospitals, surgeons and patients to choose what hip implant to use for replacement surgery.

AI making earlier detection of colorectal cancer possible

Early detection is crucial for effective treatment of colorectal cancer, but the initial stages are easily missed during endoscopy screenings. With GI Genius, Medtronic presents an AI-powered tool to help detect precancerous lesions in real-time. In an upcoming large-scale trial, the intelligent endoscopy module will demonstrate its benefit in the clinical context.

Article • HBOT to reduce toxic effects

Hyperbaric oxygen therapy shows promise after breast cancer radiotherapy

Hyperbaric oxygen therapy (HBOT) treatments could offer relief to breast cancer patients who experience late toxicities following radiotherapy treatment. To date, the handful of completed clinical trials only produced inconclusive or contradictory results. Therefore, results from the latest trial, named HONEY (Effect of Hyperbaric Oxygen Therapy on Breast Cancer Patients with Late Radiation…

Article • Transformative technology

Debating the case for AI in pathology

Artificial Intelligence (AI) remains a divisive topic within the discipline of pathology with a range of opinions over its current value and applicability in clinical settings. While most experts agree that the technology will not replace pathologists, it might still spell bad news for those who do not embrace AI in their daily practice. On the other hand, reservations persist about whether…

Article • Automated glucose monitoring

Pregnancy and diabetes: reducing complications with technology

Women with type 1 or type 2 diabetes often have difficulty getting pregnant, due to complications from the disease, being obese or seriously underweight, or having conditions like polycystic ovary syndrome. Once pregnant, they face challenges of having a safe pregnancy and delivering a healthy baby. Recent advances in diabetes technology, including continuous glucose monitoring (CGM) and most…

News • Study on vascular access options

Intraosseous or intravenous: which way to administer medication during cardiac arrest?

Research shows a one-third chance of restoring blood circulation during cardiac arrest, regardless of whether the medication is administered into the bloodstream or bone marrow.

News • Radiopharmaceutical study

New mini-protein shows promise in targeted radiation delivery to tumors

A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.

News • Transformation study

Turning labs into “discovery factories” with AI and robotics

Increasing implementation of robotic automation and AI will speed up scientific progress in science laboratories, according to a new study. The experts outline this process across distinctive levels.

Interview • Congress showcases advances

Making immunotherapy work for more cancer patients

Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.

News • Cancer treatment advances

USC study findings: early blood test forecasts survival rates in patients with metastatic prostate cancer

A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.

News • Brain cancer immunotherapy

Turning immune cells against glioblastomas

Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.

News • Experts propose combination strategy

Kidney cancer: early detection through 'piggyback' screening

Kidney cancer is relatively rare, so dedicated screening programmes would not be cost-effective. Combined with lung cancer screening, however, this would be much more feasible, a new study shows.

News • Burst wave lithotripsy

Pushing kidney stones with ultrasound

Sometimes all it takes is a little push: Using ultrasound to reposition small kidney-stone fragments significantly lowers patients’ returns to the operating room, a new study finds.

News • Trial of laboratory service

Drone delivery of blood samples debuts in London

The delivery of blood samples via drone from a hospital to a medical laboratory can save a lot of time, compared with land-based transport. A new trial explores the potential in London.

News • Planning of implant positioning

Force sensor to improve hip replacement surgery

A sensor that measures forces passing through the hip joint could help surgeons assess and balance the soft tissues before performing hip implant surgery, leading to more accurate implant positioning.

News • Strengthening the immune defense

STAb-T: new immunotherapy method shows promise against lung cancer

STAb-T, a new form of immunotherapy to treat solid tumours shows therapeutic potential in animal models with non-small cell lung cancer. The new strategy is designed to strengthen the defensive cells.

News • Antifungal resistance

Just a bit of mold? Why fungal disease should not be underestimated

While awareness for antimicrobial resistance (AMR) in bacteria is relatively high, fungal pathogens remain largely ignored – a blind spot with potentially dire consequences for global health.

News • Checkpoint inhibitor research

Five key factors predict response to cancer immunotherapy

Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.

News • Biorobotics breakthrough

Promising hand prosthesis controlled by thought and magnets

A new type of magnetically controlled prosthetic hand allows amputees to reproduce all movements simply by thinking and to control the force applied when grasping fragile objects.

News • Glioblastoma research

Brain scars from cancer treatment key factor for relapse

Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.

News • Thermal-responsive magnetic nanorobot collectives

Stopping brain bleeds from aneurysms with tiny robots

Brain aneurysms cause around 500,000 deaths globally each year and can lead to stroke and disability. Now, researchers created nanoscale robots to manage bleeds in the brain caused by aneurysms. 

News • Study on antiviral therapy efficacy

Covid-19 treatment of immunocompromised patients: better late than never

Immunocompromised patients are at greatest risk of developing severe Covid-19 after an infection. While early antiviral treatments yield best results, even late-onset therapies still show benefits.

News • Surprising study results

Coronary bypass: new insights on ‘no-touch’ vein harvesting

For coronary artery bypass grafting (CABG), a ‘no-touch’ technique to harvest the saphenous vein graft has been considered superior to the conventional approach. Surprisingly, a new study comes to a different conclusion.

News • Under-diagnosed condition

AI-enabled stethoscope helps detect pregnancy-related heart failure

An AI-enabled digital stethoscope could help doctors identify twice as many cases of heart failure during pregnancy compared to regular obstetric care and screening, acording to a new study.

Article • Oxford debate at senology congress

DCIS: pros and cons of radiotherapy

Radiologists and gynaecologists entered a veritable bout during the Oxford debate at the 43rd annual congress of the German Senologic Society in Dresden. Controversy was sparked by the question of whether all patients with a ductal carcinoma in situ (DCIS) should undergo radiotherapy.

Article • Patent for promising medical product

Breast cancer radiotherapy: new positioning system protects surrounding organs

Radiotherapy for breast cancer is always associated with the risk of damage to organs or surrounding tissue. A new positioning system, which has now been patented by the Hamm-Lippstadt University of Applied Sciences (HSHL), positions the breast far away from the upper body and thus increases the distance to the organs at risk. The medical device called "X-Akt Mamma RTX" is now set to be…

News • Towards personalised risk assessment

Training an AI to early detect dementia with big data

With enough medical training data, AI can predict health conditions with astounding accuracy. Now, researchers want to use brain scans of the entire Scottish population to have an algorithm early detect dementia.

News • Time loss vs. life expectancy gains

Dialysis: Is the tradeoff always worth it?

New research sheds light on the tradeoffs between survival and time spent in inpatient care that dialysis might entail. This could help patients with kidney failure make more informed decisions.

News • COLO-DETECT trial

Bowel cancer: AI improves early detection

Artificial intelligence (AI) can be used to great effect in colonoscopies to spot abnormalities potentially leading to bowel cancer. This is the result of the recently completed COLO-DETECT trial.

News • Promising research on oral rinse-based test

Wash, rinse – detect head and neck cancer?

Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.

News • Staging and monitoring tool

Diagnosing lung disease with quantitative ultrasound parameters

Using conventional ultrasound, researchers have developed a model that determines whether conditions such as fibrosis or edema are present in the lungs, and gives information about the severity.

News • Alternative to blood transfusion

Rhesus pregnancy: immunotherapy to protect the foetus

In rhesus pregnancy, antibodies from the pregnant mother can lead to anaemia for the foetus in the uterus. A new study suggests that a drug could serve as a non-surgical alternative.

Article • AI is key

Lung cancer screening initiatives across Europe

Artificial Intelligence will be a critical component in ensuring a Europe-wide lung cancer screening programme can achieve its potential, according to speakers at a special ECR 2024 session. Delegates heard that the SOLACE project (Strengthening the screening of Lung Cancer in Europe) will be supported by AI in terms of workflow, diagnostics, and image and data analysis.

News • Recurrence timeframe analysis

Breast cancer radiotherapy: new insights on duration of protective effect

After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.

News • Research on fitness training

Exercise after stroke: intensity matters

Extensive and moderate, or short and intense? New research suggests which approach to physical exercise is more effective for improving fitness among people recovering after a stroke.

News • Promising study results

Cancer of Unknown Primary: on the way to targeted therapies

Metastases, but no sign of the original tumor: A large international study shows how this phantom cancer can nevertheless be treated.

News • ICD usage in HF patients

Kidney dysfunction as a predictor of sudden cardiac death

A prospective study has revealed that kidney dysfunction may be a powerful predictor of sudden cardiac death. Findings could lead to revisions in the guidelines for ICD usage.

News • Synthetic nanofibers

Repairing cartilage damage with ‘dancing’ molecules

US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.

News • Lower dose, improve tolerability, retain efficacy

Prostate cancer therapy: benefits of therapy deescalation

Radiotherapy of prostate cancer often comes with side effects, causing some patients to discontinue treatment. New research shows the benefits of at lowering the dose over subsequent treatment cycles.

News • Effects of smartwatch alerts

Heart rate monitoring: wearable devices can drive anxiety, possibly affect health

For patients with atrial fibrillation, using a wearable device can lead to higher anxiety about symptoms and treatment, doctor visits, and use of informal healthcare resources, a new study finds.

News • Concerns about hurried adoption

Survey: Is medical AI taking over too quickly?

The pace of artificial intelligence (AI) adoption in personalised medicine is unsettling for great parts of the public. A new survey reflects the worried state of mind in the UK.

News • Horizon grant for "KEEPCARING"

Study to prevent burnout of surgeons and OR staff

To address the increasing stress and burnout rates among healthcare professionals, Amsterdam UMC will lead a European consortium in search of the best solutions.

News • Immunology

“One and done”: promise for a universal influenza vaccine

New research reveals a promising approach to developing a universal influenza vaccine that confers lifetime immunity against an evolving virus considered most likely to trigger the next pandemic.

News • Electronic prompt in the EHR

‘Nudging’ surgeons away from breast cancer overtreatment

Sentinel lymph node biopsies can help detect breast cancer – but not every patient benefits from the procedure. New research finds that a simple EHR prompt can prevent unnecessary surgery.

News • Biomaterial-based device

Heart valve made of human collagen opens up new treatment avenues

A new heart valve comprised of biological material obtained from human cells, opens up new therapeutic avenues for patients with paediatric heart diseases, such as tetralogy of Fallot.

News • Finding fibrosis

Hyperpolarized MRI improves early detection of kidney diseases

Using an advanced scanner, researchers have developed a technology that can detect the earliest changes in the kidney when scar tissue begins to form.

News • Tumour infiltrating lymphocyte measurement

Breast cancer: AI tool predicts which DCIS cases become invasive

Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.

News • Specific TB scan

PET imaging shows tuberculosis in the body

A new radiotracer enables positron emission tomography (PET) scans to be used for the first time to accurately pinpoint when and where tuberculosis (TB) is still active in a patient’s lungs.

Article • Professional perspectives

Theranostics: A career opportunity for Nuclear Medicine Technologists

What is an advanced clinical practitioner (ACP) and why should nuclear medicine technologists strive to become one? At the 2024 annual meeting of the SNMMI in Toronto, ACP Luisa Roldão Pereira outlined the position and its importance in the clinical context.

News • Digital support

New app triples chance to quit smoking

Finnish researchers found that using a mobile application based on cognitive behavioral therapy can significantly boost success rates of people attempting to stop smoking.

News • Iontronic technology

Slowly but steady gets the brain tumour

Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.

News • Near-infrared photobiomodulation

Noninvasive laser therapy shows promise in stroke treatment

In lab models of stroke, a research team showed that laser therapy improved blood flow in the brain and decreased stroke injury by stimulating the production of nitric oxide.

News • Brain stimulation

Treating neurological diseases with 3D ultrasound

Researchers have developed a technology for targeted stimulation of the brain with ultrasound. This could be used to treat diseases and conditions such as epilepsy, Parkinson’s disease, depression, addiction, and even the aftereffects of stroke.

Article • Interactive VR worlds in healthcare

Metaverse in medicine: between potential and pioneering spirit

For many, the term “metaverse” evokes images of VR headsets and the rebranded company behind Facebook – but can the digital parallel universe provide actual benefits for healthcare? Dr Anke Diehl has studied the technology intensively and recognises significant potential for medical applications. However, the expert for digital transformation at Essen University Medicine, Germany, cautions…

Innovative Avenue of Treatment – Internal Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer

In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.

News • Success of aRCC treatment

New biomarker to better predict immunotherapy response in kidney cancer

Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.

News • UK study confirms

Lung cancer screenings: benefits across all socioeconomic groups

Lung cancer screenings save lives – especially for those who live in economically deprived areas, a new study confirms. The researchers further demonstrate the benefits of using low-dose CT imaging.

Article • Advancements in endoscopy

Enhancing diagnosis and disease monitoring for ulcerative colitis

Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.

News • Vaccines for future pathogens

“We don’t have to wait for new coronaviruses to emerge”

A new approach to vaccine development could produce vaccines before the disease-causing pathogen – such as a new variant of the coronavirus Sars-CoV-2 – even emerges.

News • Transfusion medicine

One step closer to universal donor blood

Donor blood is a scarce and valuable resource. Researchers aim to mitigrate this by using enzymes to remove specific sugars that make up the A and B antigens in the human ABO blood groups.

News • Missed in MRI

Multiple sclerosis: PET scans reveal 'hidden' inflammation

In some patients with multiple sclerosis (MS), symptoms worsen during treatment, but MRI scans do not indicate any change. In such cases, positron emission tomography could help, a new study suggests.

News • MRSA and other infections

Researchers develop vaccine to fight antibiotic resistance

Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.

News • Atrial fibrillation early warning

Deep learning predicts heart arrhrythmia 30 minutes in advance

Researchers have developed a deep-learning model that predicts the transition from a normal cardiac rhythm to atrial fibrillation 30 minutes before onset, with an accuracy of around 80%.

News • Urine-based diagnostics

New prostate cancer test to help avoid unnecessary biopsies

US researchers have developed and validated a new urine-based test for prostate cancer, which was shown to meaningfully reduce unnecessary prostate biopsies while providing highly accurate detection.

News • Nuclear medicine

Prostate cancer: New SPECT/CT technique for greater treatment precision

A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.

News • Mechanistic subtypes

The telltale traces long Covid leaves in the blood

Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.

News • Minimally invasive procedure

Aortic valve replacement: TAVR on par with surgical approach

Decreased rates of death and stroke: new research shows the validity of transcatheter aortic valve replacement in low-risk patients. This advocates a less invasive alternative to surgical options.

News • Biparametric scan

Prostate cancer screening: two-part MRI is enough, study shows

A three-part ‘multiparametric’ MRI of the prostate is standard of care in the UK for patients suspected of having prostate cancer. Now, a study shows two-part scans are sufficient for diagnosis.

Article • Prostate cancer treatment

MR-guided radiotherapy: a potential game changer

Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.

News • Preventive blood test

Prostate cancer screening: Study advocates 5-year-interval

How often should men get checked for their level of PSA, a marker for prostate cancer? A German study involving over 12,500 men shows that a five-year interval between tests is safe.

News • Omitting axillary lymph node removal

Breast cancer trial explores benefits of less extensive surgery

A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.

News • Technique comparison study

Oesophageal cancer: standard or keyhole surgery?

When treating oesophageal cancer, surgeons may have a preference towards either open surgery or keyhole techniques. Now, a study explored superiority of one over the other in terms of recovery time and complications.

News • BRCA1 and BRCA2 malfunctions

Targeting 'exhausted' immune cells to prevent breast cancer

A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.

News • 3D mammography

Trial shows benefits of digital breast tomosynthesis in breast cancer screening

A clinical trial has revealed the effectiveness of '3D mammography' in reducing by almost half the incidence of interval breast cancer appearing between two rounds of screening.

News • Promising study

Pre-operative PET-MRI to improve breast cancer treatment

A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.

News • Tumor organoid platform

Personalized 3D bioprinting to advance gastric cancer treatment

Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.

News • Chemotherapy and novel surgery technique

Study explores new approach to 'inoperable' pancreatic cancer

US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.

Endoprostheses for elderly and frail patients: Preparation is half the battle

An ageing population and modern lifestyle conditions have greatly increased the case numbers for hip arthroplasty. To prevent complications, it is important for orthopaedic surgeons to identify high-risk patients and take proper precautions. At the Heraeus symposium at DKOU, two experts explored the special measures that should be taken to ensure better outcomes for elderly and frail patients.

News • Accurate detection and removal

Radioguided surgery to treat metastatic lymph nodes in prostate cancer

Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.

News • Memory impairment

"Chemo brain": gamma waves may be key to protection

Researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating memory impairment and other cognitive effects of chemotherapy.

News • Personalised oncology

New platform to significantly reduce cancer drug testing and screening time

In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.

News • Follow the evidence

Optimising preventive measures to stop surgical infections

Why are we doing what we are doing to stop surgical infections? A new research review in the run-up to the ECCMID congress 2024 will look at improving preventive measures.

News • Telesurgery

First robot-assisted remote radical distal gastrectomy with 5G technology

A potential milestone for telesurgery: a team of researchers from China reported the first robot-assisted remote radical distal gastrectomy performed using 5G communication technology.

News • Alternative to endoscopy

Sponge-on-a-string test as less invasive method to diagnose oesophageal cancer

A new test to help diagnose Barrett’s oesophagus – a condition that can lead to oesophageal cancer – has reduced the need for invasive endoscopy in thousands of low-risk patients.

News • Wearable medical device

Vibrating glove helps stroke patients recover from muscle spasms

After a stroke, patients often experience uncontrollable spasms of their arms and hands. Engineers have developed a glove-like wearable medical device that offer relief for the condition.

Article • During lumpectomy

Fluorescence-guided surgery identifies breast cancer in margins

Breast surgery is a traumatic experience for a woman, no matter whether breast-conservation surgery (BCS) or a mastectomy. Trauma levels are greatly enhanced, if pathological evaluation findings of an excised breast tumour following a lumpectomy suggest that additional cancer may still be in the margins, and a second surgical procedure is required. A new system with the ability to accurately…

News • Accelerated sample analysis

Digital pathology cleared for use in cancer screening programmes

Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.

News • Molecular machines

Killing cancer cells: the 'jackhammer' approach

Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.

Article • Experts explore impact of technology

AI in radiology: helper or bane of society and the environment?

The climate crisis and AI – arguably two of the most hotly-debated and relevant topics of our time – share an intricate relationship: While computation of complex AI routines commands an immense carbon footprint, it is these algorithms that might be the very key to mitigate the effects of global warming. In a dedicated session at ECR 2023, radiologists explored the societal and environmental…

News • Promising study in mice

Exploring the potential of mRNA technology for rare diseases

Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.

News • Training course and sound therapy

Can an app train the brain to overcome tinnitus?

Tinnitus is common, affecting up to one in four people. Now a study shows that the debilitating effects on mental health can often be reduced via training and sound therapy in a smartphone app.

News • Point-of-care diagnostic platform

Inhalable sensors for early lung cancer detection

Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.

News • Emergency decision assistance

Research: In-ambulance AI support could save more lives

If healthcare professionals could get support making fast-paced, life-critical decisions from an AI tool, more lives could be saved, according to new research results from Sweden.

News • Automa+ Congress

Towards tomorrow: Insights from Zurich on pharma's progressive trajectory

The Automa+ 2023 congress has brought fascinating insights into the pharmaceutical landscape. This article distills highlights from the congress, illuminating the paradigm-shifting strides that are set to propel the pharmaceutical industry into a future characterized by interconnected, empathetic, and forward-thinking practices.

Article • Technology-based therapy approach

Self-administered brain stimulation as a novel tool for depression treatment

Given the limited success of traditional therapies for depression, recent years have witnessed the emergence of technology-based interventions. One such intervention is transcranial electromagnetic stimulation (TMS).

News • Fullness simulator

This vibrating, ingestible capsule might help treat obesity

When your stomach is full after a large meal, certain receptors are activated to tell the brain. A newly developed capsule could provoke this fullness signal early, potentially helping with treating obesity.

News • Novel treatment strategy

Antibacterial nanoparticles to shorten tuberculosis therapy duration

A low-cost technology involving nano-sized antimicrobial compounds against tuberculosis has been developed by researchers at São Paulo State University (UNESP).

News • "Gene scissors" vs. sickle cell disease

FDA approves first CRISPR/Cas therapy

It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.

Article • Digital breast tomosynthesis

Transforming breast screening: The role of AI in improving reading workflow

While having more centers adopt digital breast tomosynthesis (DBT) for breast cancer screenings into their practice is a positive change, it also presents some challenges for radiologists—particularly the increased number of images for radiologists to review. This challenge has paved the way for AI to offer innovative workflow solutions for radiologists that do not sacrifice accuracy.

News • National policies benchmark

Dementia care and treatment: Continuing inequalities across Europe

According to the European Dementia Monitor, there is still a clear East/West divide, with significant differences between countries in terms of availability, affordability, legal and human rights.

Video • Digital design-to-manufacturing process

3D printing personalised prosthetics anywhere in the world

A fully digital design-to-manufacturing process developed at Loughborough University has the potential to revolutionise lower limb socket production by allowing printing outside of hospital settings.

News • Troponin assessment

Blood test aids emergency diagnosis of heart conditions

A high sensitivity blood test can improve diagnosis for one in five patients who have a heart muscle injury, according to new research.

News • Encouraging results of DARS trial

A ‘new gold standard’ for head and neck cancer radiotherapy

New research suggests a new approach to precision radiotherapy can reduce the risk of swallowing problems for patients, without impacting the success of treatment.

News • Opportunistic screening using chest X-rays

AI identifies non-smokers at high risk for lung cancer

Incidence of lung cancer among people who never smoked is rising. A new AI tool opens the door for opportunistic screening for this group, using existing chest X-rays in the electronic medical record.

Article • Trade fair presence

Taiwan blends tech and tradition at Medica 2023

AI features for automation, integrated systems and more: the role of medical technology has never been as vital as today, and MedTech companies from Taiwan are putting their best foot forward to contribute. At the 2023 Medica trade fair, visitors of the Taiwanese pavilion not only had the opportunity to see the latest medical products on display, but also get acquainted with Taiwanese culture in…

News • First human clinical trial

Pill-sized device monitors breathing from the gut

Scientists have developed an ingestible device that can safely monitor vital signs like breathing and heart rate from inside humans, providing accessible and convenient care for people at risk of opioid overdose.

News • Nuclear medicine

Prostate cancer: staging issues in bone scans compared with PSMA PET

Bone scans have been found to overstage prostate cancer at initial staging compared to prostate specific membrane antigen (PSMA) PET, according to new research.

News • Septoplasty assessment

Crooked septum: surgery beats nasal spray

Surgery to straighten a crooked septum (the thin wall of bone and cartilage dividing the space between the two nostrils) is more effective than nasal sprays, a new study suggests.

Article • Technology overview and outlook

AI in healthcare: Significant potential – and serious obstacles

Sure, AI still has a long way go. But maybe one day in the not-so-distant future, AI will provide us with information about our current state of health, such as the number of red blood cells, cholesterol levels, fat percentage, and how many seconds last night's beer will shorten our life expectancy.

News • RENACER repository

Brain cancer tissue samples to gain new insights

A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.

News • Mobile point-of-care imaging

An MRI-equipped ambulance: A game-changer for stroke care?

Because time is brain: To explore the potential for accelerated stroke diagnostics, US researchers equipped an ambulance with a portable MRI – with promising first results.

News • Platform for new companies

MEDICA 2023: Start-ups are shaking things up

MEDICA trade fair (Nov 13-16, Düsseldorf) is a major event for start-ups entering the health sector. Hundreds of young developers seek business contacts for cooperation concerning funding, production, approval, marketing or sales of their products.

News • Good killer cells

Cellular immunotherapy: a new approach against cancer

Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.

News • Glioma imaging

PET imaging for more effective treatment of aggressive brain tumors

Advances in positron computed tomography (PET) could lead to a more refined approach to the precise removal of brain tumors is on the horizon, experts from Poland point out.

News • IC before CRT

Cervical cancer: Improved treatment course increases survival, reduces recurrence

New trial results suggest that a short course of induction chemotherapy prior to chemoradiation could reduce the rate of relapse and death among patients with locally advanced cervical cancer.

News • Sensorised equipment

'Smart' scalpel could help doctors hone surgical skills

Scalpels with built-in sensors could streamline training for surgeons and pave the way for procedures performed by robotic devices, a study suggests.

News • Postpartum hemorrhage

Two easy fixes to reduce bleeding after C-section

Postpartum hemorrhage is a leading cause of maternal mortality at birth, especially after cesarean deliveries. Now, anesthesiologists propose two simple solutions to help prevent the severe bleeding.