News • Neurodegenerative diseases
New biomarker improves diagnosis of Parkinson's and LBD
A biomarker discovered in the cerebrospinal fluid could improve diagnosis of Parkinson's disease and dementia with Lewy bodies.
Search for: "protein" - 250 articles found
News • Microscopic medicines
Intrabodies unlock new treatments for MND and Alzheimer's
New treatments for neurodegenerative diseases like Alzheimer’s, Parkinson’s, and motor neurone disease (MND) could be unlocked thanks to microscopic medicines called intrabodies.
News • pTau217 and BDTau
Siemens Healthineers expands brain health research portfolio with new biomarker assays
Siemens Healthineers has announced the availability of two blood-based biomarker tests for research use: the Atellica IM Phosphorylated tau 217 (pTau217) and the Atellica IM Brain Derived Tau (BDTau) assays. Both are run on the Atellica Solution IM and Atellica CI Analyzers.
News • Neuro-oncology
Simple blood test could detect glioblastoma in the future
Glioblastoma is notorious for late diagnosis, rapid progression, resistance to treatment and its biological complexity. A new experimental method could help detect this deadly type of brain cancer.
News • Unexpected similarities
Different tumours, same origin: Surprising discovery in paediatric brain cancers
Researchers discovered that pineoblastoma, retinoblastoma and medulloblastoma – severe brain tumours in children that appear to be completely different – actually arise from the same type of cell.
News • tRNA reprogramming mechanism identified
New therapeutic target to curb coronavirus spread
Coronaviruses can generate new variants capable of infecting humans after circulating in animal reservoirs. Researchers develop broad-spectrum antiviral drugs to curb the spread of these pathogens.
News • Adhesive microgel-based coating
A spray-on shield to prevent transplant rejection
Korean researchers are developing a “spray shield that adheres to transplant organs” and reduces the burden on patients taking lifelong immunosuppressants to prevent transplant rejection.
News • Lymphovenous bypass
A surgical treatment for Alzheimer's disease?
A small but growing body of evidence suggests that a minimally invasive surgical procedure called lymphovenous anastomosis (LVA) might be an effective treatment for Alzheimer's disease.
News • (B)eating cancer
Bacteria to consume tumours from the inside out
A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.
News • Cancer “chronotherapy”
Beating cancer by the clock: Why the time of day matters for radiotherapy
Radiotherapy is more effective when administered at the right time of day, according to new research. This discovery opens the door to cancer “chronotherapy”, the researchers hope.
Article • Digital pathology and AI
Finding new biomarkers to match the biological complexity of cancer
Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…
News • Research on metastasis mechanism
How ovarian cancer hijacks abdominal cells as an invasion force
Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.
News • CTNNB1 in focus
Mutation strength may hold key to personalized cancer treatment
Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.
News • Research on dopaminergic neurons
Immunotherapy to prevent neuron loss in Parkinson’s disease
Promising new research points to a new immunotherapy approach that could help preserve viable neurons in people with Parkinson’s disease.
News • Liquid handling
New solution for low-volume dispensing presented at SLAS 2026
Analytik Jena will be presenting new automation solutions for laboratory workflows at the SLAS 2026 International Conference & Exhibition (February 7–11). A particular highlight is the launch of the PULSEspencer R – the first model in a digital and contactless dispenser series in the company's portfolio.
News • Laboratory equipment
CE IVDR certification for new benchtop hematology analyzer
Analytical and measurement technology copany Horiba has obtained CE IVDR certification for its new Yumizen H500 CRP benchtop hematology analyzer, designed for small laboratories.
News • Plasma protein profiling
Blood test spots cancer in patients with unspecific symptoms
Non-specific symptoms such as fatigue, pain or weight loss can be caused by cancer, another serious condition or something completely harmless. A blood test can help provide relevant information.
News • Study explores regenerative potential
How the heart regrows muscle cells after a heart attack
Pioneering research has shown that heart muscle cells regrow after a heart attack, opening up the possibility of new regenerative treatments for cardiovascular disease.
News • Neurosciences
New insights on the onset of Huntington's disease
Why does Huntington’s disease begin at very different ages? Using advanced AI techniques, neuroscientists from the University of Barcelona found a way to better answer this question.
News • Amyloid-β-induced functional placental impairment
Researchers link Alzheimer’s disease protein to preeclampsia
Researchers have discovered that amyloid-β deposits - similar to those found in Alzheimer’s disease - may contribute to the development of preeclampsia during pregnancy.
News • Brain-derived neurotrophic factor
Asthma-related depression distinct from MDD, new study finds
Symptoms of depression are common among people with asthma, but growing evidence suggests they may arise from biological mechanisms different from those underlying major depressive disorder.
News • Disease tolerance and infection pathogenesis
Different age, same infection treatment? Not a good idea, study finds
Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
News • Focus on tumor STAT1 acetylation
How cancer cells learn under pressure to evade immunotherapy
Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.
News • Immune response to viral infection
Multiple sclerosis: how EBV can evoke nerve damage
The immune system’s reaction to the common Epstein-Barr virus (EBV) can ultimately damage the brain and contribute to multiple sclerosis (MS), a new study shows.
News • Intragenic complementation
Rare disease genetics: two wrongs actually can make a right, study shows
Scientists have overturned a long-held belief in genetics: that inheriting two harmful variants in the same gene always worsens disease. Instead, this can actually restore normal protein function.
Article • Personalised medicine
Gene-editing technologies: from lab to patient
Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
News • Drivers of gray matter injury
Multiple sclerosis: Promising biomarker linked to progression and brain inflammation
A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.
News • Between the heart and the brain
Why cardiovascular disease and depression often develop together
Cardiovascular disease and depression do not co-occur by chance; the TO_AITION project aims to enable earlier diagnosis of comorbidity, better risk prediction and personalised treatment strategies.
News • New treatment approach
Ultrasound 'softens up' tumors before chemo
To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.
News • Brain damage analysis
Blood biomarker predicts recovery after cardiac arrest
A simple blood test that can very accurately predict the chance of survival with good recovery could be of great significance for patients in intensive care after a cardiac arrest.
News • Exploration of novel biomarkers
Depression: not just a disease of the mind
Depression is not only a disease of the mind or the brain, a new study finds: a research team has revealed deep connections to abnormalities in the body's overall immune response.
News • Sex-specific dysregulation
Why women are three times more likely to get severe long Covid
New research reveals why women with long Covid — especially those who develop chronic fatigue syndrome — tend to experience more severe and persistent symptoms than men do.
News • Ultrasound-guided gene therapy
New approach for targeted seizure control without surgery
New hope for patients with neurological diseases: A combination of focused ultrasound and gene therapy enables targeted, nonsurgical control of seizure-relevant brain regions.
News • Dual-barrier tumours
How colorectal cancer evades immunotherapy (and what to do about it)
Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.
News • Selective degradation of neurons
ALS: Key mechanism behind motor function loss discovered
Why does amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, attack motor neurons, the cells that control body movement, while others are spared? A new study may have found an answer.
Article • Reshaping GI cancer care
Pathologists at the heart of precision oncology
Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…
News • Nuclear medicine
PET imaging reveals which patients will (or will not) recover after heart attack
A new approach to PET imaging offers a promising way for physicians to promptly identify patients who are at risk for poor functional recovery after a heart attack, according to new research.
News • Proteins for personalized treatments
Tracking Duchenne muscular dystrophy with blood biomarkers
Newly discovered blood biomarkers may offer new options to track Duchenne muscular dystrophy (DMD) in a less invasive way than physical tests or biopsies. This could support more tailored treatments.
News • Radiation-induced cognitive decline
New approach to protect the brain during radiation therapy
Researchers identified a targeted way to protect the brain from harmful side effects of cranial radiation therapy, potentially preserving the quality of life for millions of brain cancer survivors.
News • New imaging solution
PSMA PET to detect prostate cancer recurrence
A novel imaging solution, called PSMA PET scanning, can more effectively detect the recurrence of prostate cancer compared to standard methods, and is associated with improved survival outcomes.
News • Focus on Helicobacter pylori
Towards a vaccine against ulcers, stomach cancer
Scientists are on the way to finding a vaccine to fight off Helicobacter pylori - a bacterium found in over 60% of people - possibly preventing stomach ulcers and lowering the risk for stomach cancer.
News • Peripheral immune tolerance
Immune system researchers receive Nobel Prize 2025 in Medicine
The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.
News • AML targetable immune escape mechanism
How leukemia cells trick the immune system
Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.
News • Microbiome
Fatty acids fuel cancer-promoting gut bacteria
TU München researchers discover how chronic cellular stress changes gut microbiome composition, promoting cancer development through altered lipid metabolism.
News • Diagnostics
Fast candida detection through sugar pattern analysis
Scientists created precise replicas of Candida sugar coats to understand immune responses, enabling fast bedside testing that could replace slow lab cultures.
News • Research
Stuttgart researchers enhance CRISPR for cellular analysis
University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.
News • New method to study embryonic implantation
Improving the odds for assisted reproduction
Assisted reproductive technologies like IVF are held back by the fact that more than half of all embryos fail to implant into the uterus. Now, new research explores ways to improve these odds.
News • Materials science meets medicine
Exploring why implants fail in the body
Even though many implants such as artificial joints and pacemakers are made of titanium, they occasionally break – but why? A researcher is investigating implant failure and how to prevent it.
News • Research on Antrodia cinnamomea
Promising fungal compound to fight cancer and inflammation
Studies have found that natural polysaccharides from a medical fungus endemic to Taiwan can not only effectively inhibit inflammation, but also fight the proliferation of lung cancer cells.
News • Crafting safe and appeling foods
Beyond just goo: 3D printing meals for dysphagia
Dysphagia can significantly reduce a person's quality of life. Now, research teams have developed a new 3D bioprinting method to create safe and appealing meals for dysphagia diets.
News • Fluorescent 18F-PET imaging
Dual-mode PET tracer lets surgeons see – and hear – prostate cancer
Tracer molecules serve to provide visual guidance in nuclear medicine, but a new molecule could give surgeons additional audio cues to help them locate prostate cancer tumors and metastases.
News • Microsatellite instability
Predicting tumor MSI status for precision cancer treatments
Microsatellite instability-high (MSI-H) tumors are associated with better clinical outcomes. A novel AI model for accurate MSI prediction could help battle gastric and colorectal cancers.
News • Goodbye to the needle
Replace injections with pills? New technology could make it happen
Some medications can only be taken as an injection, which is often painful, unpleasant and inconvenient for patients. A new transport system could make it possible to swap these injections for pills.
News • Patient involvement enables research
Tumor vesicles as a promising biomarker for early cancer detection
Tumor vesicles may serve as early indicators of cancer and help monitor the effectiveness of treatments. Now, researchers discovered a new way to detect these vesicles.
News • Predictive phenotypes
Ovarian cancer: new insights into immune landscapes
Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.
News • Viral persistence in the brainstem
Long Covid: Researchers find clues for "brain fog" origin
After an infection with the coronavirus Sars-CoV-2, the virus is able to persist at low levels in the brainstem, new research finds. This helps explain some of the enduring neurological symptoms.
News • Risk of misclassification
Prostate cancer: why “low-grade” might not be “low risk”
Classifying prostate cancer as “low-grade” could create a false sense of security and delay definitive treatments. A new study shows that the biopsy grade alone can paint an incomplete picture.
News • Respiratory viruses wake up cells in the lungs
How Covid-19 and flu infections revive dormant breast cancer
Common respiratory infections such as influenza and Covid-19 can awaken dormant breast cancer cells that have spread to the lungs, setting the stage for new metastatic tumors, new research finds.
News • Mitochondria-derived nuclear ATP surge
Pressed to the limit: New study explores cancer cell defense mechanism
How cancer cells survive the journey through the body to form metastases is still poorly understood. New insights into how cells survive intense physical stress could pave the way for new treatments.
News • Rapid exosome isolation and detection
Researchers develop at-home skin patch test for melanoma
Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.
News • Enhanced imaging and surgical guidance
Fluorescent bacteria light up tumors like a neon sign
A new, bacteria-based contrast agent illuminates tumors like a neon sign during surgery, enabling more precise resection and reducing the risk of recurrence.
News • Beyond the mammogram
Cracking the code of breast calcifications – with geology?
Dense calcifications are common in breast tissue, but not every finding in a mammogram is a precursor of cancer. New insights could lead to fewer benign biopsies and guide therapeutic development.
News • Proteomic-based score
AI measures tumor ‘stemness’ to predict cancer aggressiveness
A new AI-based tool measures cancer aggressiveness by analyzing the ‘stemness’ of tumors – their similarity to pluripotent stem cells. This could pave the way for new therapies.
News • Targeted drug delivery
Wireless NFC implant delivers chemotherapy deep into tumors
Korean researchers have developed a wireless implantable drug delivery system that enable chemotherapy drugs to penetrate deep into solid tumors—without harming surrounding healthy tissue.
News • Neural network screening tool
AI-enhanced ultrasound early detects cardiac amyloidosis
A neural network AI has been trained to detect cardiac amyloidosis from a single echocardiogram video of the heart's apical four-chamber view and differentiate it from similar heart conditions.
News • Under-the-skin glucagon reservoir
Diabetes: emergency implant to stave off hypoglycemia
An implantable device could save diabetes patients from life-threatening hypoglycemia. Remaining under the skin, it can be triggered to release glucagon when blood sugar levels get too low.
News • Microgravity-accelerated degeneration
Muscle tissue in space gives new insights on sarcopenia
Muscle tissue undergoes specific changes in space due to the absence of gravity. Investigating these changes opens opportunities for studying sarcopenia, which takes decades to develop on earth.
News • Dual role of tau phosphorylation
Surprising find: Alzheimer's biomarker found in newborn brains
What do the brains of newborns and patients with Alzheimer's disease have in common? Researchers have discovered a surprising shared trait - which might provide new insights into the disease.
News • Chromatin remodeling
New protein targets for cancer treatments
A research team at the University of Geneva has identified two new proteins that regulate gene expression, a discovery that could pave the way for new cancer and brain disorder treatments.
News • Research into immunocompetence
Early infection defense mechanism discovered in embryos
New research shows how embryos can protect themselves from bacterial infections even before forming their immune system. The findings could provide new insights into the origin of immunity.
News • Fluorescent probe
New visualisation tool targets breast cancer dissemination
In a new study, researchers have developed a new fluorescent probe to visualise signaling dynamics in moving cancer cells, to uncover a new therapeutic possibility for limiting breast cancer spread.
News • Precision medicine
Melanoma: with 43,000 data points to tailored treatments
Using nine different molecular biological technologies, researchers were able to precisely measure the properties of a melanoma tumor in four weeks and enable a precise treatment decision.
News • Stratification of TSCC immunotypes
Tongue cancer: Immune profiling for improved outcomes
Tongue squamous cell carcinoma, the most common type of oral cancer, is a challenging target for immunotherapies. Researchers now identified five immunotypes to better predict treatment response.
News • Early detection of life-threatening conditions
Newborn immune profiling to improve neonatal care
Newborns, especially those born prematurely, are vulnerable to conditions such as sepsis. A new device profiles an infant’s immune function from a single drop of blood to improve neonatal care.
News • Promising protein analysis tool
New blood test to enable rapid diagnosis of rare genetic diseases
An Australian research team has developed a blood-based method of analysing thousands of proteins in a single, untargeted test. This potentially enables rapid diagnosis of many rare genetic diseases.
Daniela Oprea-Lager
Pushing the boundaries of theranostics
Nuclear medicine specialist Daniela Oprea-Lager has been appointed Professor of Theranostics at Radboudumc / Radboud University. Her research focuses on the combination of diagnostics and treatment using radioactive substances, with particular interest for urological tumors, especially prostate cancer.
News • From neutrophil to PMN-MDSC
Blood cell corruption identified as path to severe Covid
A US research team has shown that Sars-CoV-2 can “reprogram” pathogen-fighting white blood cells into immune system suppressing cells — a potential mechanism by which severe Covid may arise.
News • Amyotrophic lateral sclerosis
New insights on ALS onset opens paths to earlier treatment
New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.
News • New insights on CLEC5A
Immune gene discovery could prevent memory loss in Alzheimer's patients
A gene once believed to fight only viral infections could also hold the key to preventing memory loss in Alzheimer’s patients, a new study finds. This paves the way for new drug developments.
News • ABO antigen analysis
Blood type A identified as breast cancer risk factor
Does having blood type A increase the risk of breast cancer? A new systematic review and meta-analysis involving more than 13,000 breast cancer patients suggests a connection.
News • Advance against back pain
3D bioprinting a functional spinal disc
Researchers used state-of-the-art 3D bioprinting to replicate the complex structure and environment of spinal discs. Their insights hold promise for understanding back pain and disc degeneration.
News • In vivo sound printing
One step closer to 3D printing inside the body
A team of scientists has developed a method for 3D printing polymers at specific locations deep within living animals.
Article • San Antonio Breast Cancer Symposium (SABCS)
Young women and breast cancer: research in focus
At the San Antonio Breast Cancer Symposium (SABCS), three experts presented new approaches and study results for the treatment of breast cancer in young women.
News • Retinal functional impairments as biomarkers
Eye exam shows potential for early detection of Parkinson's disease
Researchers from Université Laval discovered that the retina of people with Parkinson's disease responds differently to light than that of healthy people. This offers new diagnostic options.
News • Focus on mutation frequency decline
A new strategy to combat antibiotic resistance
Finding ways to target antibiotic-resistant bacteria is a scientific and medical priority. A consortium of researchers identified a compound capable of blocking a key protein for virulence, thus “disarming” the pathogenic bacteria.
News • Combining spatial transcriptomics, pseudotime and machine learning
More precise than PSA: New biomarkers for prostate cancer found in urine
Using AI and extensive analyses of gene activity in tumours, researchers have found new, precise biomarkers to diagnose prostate cancer at an early stage through a simple urine sample.
News • Spatial transcriptomics and ECM imaging
3D insights into the tumor microenvironment
Unprecedented insights into the inner workings of an early-stage lung tumor: An international research team describes a new method for 3D mapping cellular interactions in the tumor microenvironment.
News • Fibroblasts promote tumor growth and spread
Study explores reasons behind high aggressiveness of pancreatic cancer
Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.
News • Bioengineered scaffolds
New hydrogel to improve CAR T immunotherapy
Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.
News • Pulsed infrared light to enhance diagnostics
Finding the ‘fingerprints’ of cancer
New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.
Anastasia Khvorova, PhD
Pioneering work in the field of RNA-based therapies for Huntington's disease
RNA researcher Anastasia Khvorova, PhD, professor of RNA therapeutics at UMass Chan Medical School, will receive this year's Else Kröner Fresenius Prize for Medical Research on May 15, 2025. The award ceremony will be a part of the festive event together with the Fresenius SE & Co. KGaA celebrating the 100th birthday of Else Kröner, at the Städel Museum in Frankfurt am Main.
News • Study on Staphylococcus aureus
Understanding bacterial antiviral defenses to tackle antibiotic resistance
In a new study, researchers show that the emergence of antibiotic resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.
News • Targeting early versions
A 'head start' in the race against pancreatic cancer
Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.
News • Double Stokes polarimetric microscopy
New method to help accelerate cancer diagnosis
A new method to quickly and accurately analyze the structure of collagen in tissue shows promise to improve the diagnostics of cancer and other diseases.
News • Duchenne muscular dystrophy
Impact of DMD on the brain may be reversible, study finds
New research has revealed how Duchenne muscular dystrophy (DMD) also profoundly affects the brain, leading to cognitive and behavioural challenges that are very diverse and some could be reversible.
News • Nuclear imaging
PET radiotracer reveals inflammation in the brain
Using the COX-2 enzyme, a new PET imaging approach offers a never-before-seen view of inflammation in the brain, opening the door for clinical and research settings for various brain disorders.
News • Systemic cell rewiring
How midkine helps tumours evade immunotherapy
Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.
News • Alleviating inflammatory skin disorders
Microneedles to speed up diabetic wound healing
Researchers have developed ‘sponge-like’ microneedle patches that deliver bioactive ingredients and reduce inflammation in slow- and non-healing diabetic wounds.
News • Machine learning analysis
Breast cancer: AI predicts metastasis from recurrence
The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.
News • Extracellular microenvironments
Advancing diabetes treatment with 3D bioprinting
Leveraging bioink from pancreatic tissue and 3D bioprinting, researchers developed a structure closely mimicking the structure of a pancreas, in which cultured cells can resume insulin production.
News • Therapy innovation
Four advances that could change tuberculosis treatment
World TB Day raises awareness about tuberculosis and commemorates the discovery of the source bacterium M. tuberculosis. More than a century later, scientists still refine anti-TB strategies.
News • Nuclear medicine
Lung fibrosis: radiopharmaceutical improves diagnosis and monitoring
Nuclear medicine specialists have successfully used the radiopharmaceutical Ga-68-Trivehexin from Trimt to accurately diagnose patients with pulmonary fibrosis and concurrent lung cancer.
News • Plasma vs. whole blood resuscitation
Trauma surgeons propose ‘precision transfusion’ approach
Giving separated blood plasma improves outcomes in patients with traumatic brain injury (TBI) or shock, whereas unseparated or “whole” blood may be best for patients with traumatic bleeding.
News • Reseach on neurofilament light chain proteins
ALS: Improving diagnosis and management with new blood test
A new blood test, using neurofilament light chainproteins as biomarker, could lead to better diagnosis and management of amyotrophic lateral sclerosis (ALS).
Article • Imaging modalities for quantifying myocardial blood flow
Nuclear cardiology – a nuclear perspective on matters of the heart
Nuclear cardiology is a specialised field in nuclear medicine that evaluates the heart function to help diagnosing conditions such as coronary artery disease and to assess treatment efficacy, whilst minimising invasive procedures like biopsies. More recently, clinicians have increasingly opted for nuclear imaging over endomyocardial biopsy to diagnose cardiac amyloidosis, allowing for earlier…
Video • Zwitterion research
Polymer coating to prevent blood clotting in medical implants
Researchers at the University of Sydney are using so-called Zwitterions to create a surface coating that could stop blood clotting in medical devices and implants like catheters and stents.
News • Multi-omics-based prediction
Pancreatic cancer: 'biomarker panel' brings hope for early detection
The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.
News • Hyper-elevated RNAPII detection
New biomarker predicts aggressiveness of brain, breast cancer
Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting the aggressiveness of meningioma brain tumors and breast cancers.
News • Study explores impact
How brain trauma can trigger Alzheimer's disease
Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.
News • Micro Immune Response On chip (MIRO)
Replicating tumours to assess cancer immunotherapy efficacy
Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.
News • Research on RAD51 biomarker
Next-generation sequencing for personalizing prostate cancer treatment
Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.
News • Quantification of serum biomarkers
Early detection of lung cancer with low-cost biosensor
A sensor, similar to glucose monitoring devices, detects lung cancer biomarkers from a blood sample in just 40 minutes. The technology has potential to identify at-risk patients and tailor treatments.
News • Exploring the neurovascular unit (NVU)
Promising new approach to detecting Alzheimer's
Research suggests a new approach to detecting Alzheimer’s disease: changes in brain oxygenation dynamics and neuronal function contribute to the neurodegeneration.
News • Detection of glial fibrillary acidic protein (GFAP)
Blood test may detect stroke type before hospital arrival
A new blood test that detects a specific brain protein may help doctors determine the type of a stroke faster and allow them to start safe treatment for people before they get to the hospital.
News • Pyroptosis propagation
Sepsis, or death by lethal message
Dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues report. Their findings could lead to a new understanding of this dangerous illness.
News • Oncological gynecology
Cervical cancer: HPV vaccine to get rid of precancerous lesions
Infection with the human papillomavirus (HPV) is the most common cause for cervical cancers. Now, researchers have developed a promising therapeutic vaccine against precancerous lesions.
News • Molecular mechanism discovered
Researchers find a way to stop harmful cells after cancer treatment
Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.
News • Paediatric research
Molecular ‘fingerprint’ of long Covid in children's blood discovered
A new study has shown that the molecular signature of long Covid can be found in blood samples of children. Using an AI tool, the researchers were capable of diagnosing the condition with 93% accuracy.
News • Immuno-monitoring study
New ways for childhood cancer immunotherapies
The immune system of children reacts differently to cancer than that of adults. New insights into these differences have the potential to lead to new tailored treatments for children with cancer.
News • Variation in attitudes to biopsy practice
Global gaps in diagnosing kidney disease revealed
When is a biopsy needed to diagnose a kidney disease? This is handled very differently around the world, a new study finds. This could result in adverse patient outcomes, the researchers warn.
News • Research on MRD in tongue cancer
Understanding chemotherapy resistance in oral cancers using organoids
Tongue cancer cells can become resistant to chemotherapy under certain circumstances. Investigating these mechanisms, researchers shed light on promising avenues toward new treatments for this cancer.
News • Potential for neurodegeneration
Head injuries may activate dormant viruses, trigger neurodegeneration, study finds
More than just a sports injury: A new study shows that head trauma may activate latent viruses, leading to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease.
News • Checkpoint inhibitor immunotherapy efficacy
AI tool uses routine blood tests to predict cancer immunotherapy response
Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.
News • Immunology
Researchers discover new type of anticancer T-cell
A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.
News • Bacterial-induced host metabolic shift
How Salmonella can lead to colon cancer (and how it may be stopped)
Infections with Salmonella can increase the risk of colon cancer. New research sheds light on how this bacterium can cause this. The findings provide new leads for new treatments.
News • Surprising insights
Herpes infection might drive Alzheimer's, study suggests
Researchers uncovered a surprising link between Alzheimer’s disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease.
News • Driving mechanism identified
Why the lung is a frequent site of cancer metastasis
More than half of cancer patients in whom the cancer spreads beyond the primary site have lung metastases. What makes the lungs such a tempting place for cancer cells? New research may have an answer.
News • Research into new therapies
How natural killer cells could fight leukemia more effectively
Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.
News • PET compound
New radiotracer lights up aggressive cancer tumours
A new radiotracer – an injected compound used in PET scans – could help inform doctors that a patients aggressive cancer will not respond to chemotherapy before treatment is given.
News • Cancer development research
Exploring the role of sex in tumor growth
Tumors in female fruit flies grow significantly larger than in male ones, a new study finds. The findings could lead to a better understanding of how the biological sex impacts cancer development.
News • Clinical decision aids
Just a fever or sepsis? New way to treat babies without invasive tests
New study results could help detect whether a newborn baby with fever has sepsis or another serious bacterial infection, without the need for invasive testing.
News • Striking structural reorganisation
Pregnancy and nursing massively changes up mothers' intestines
When women are pregnant and nurse their babies, their bodies change to ensure the health of both mother and child. Researchers now surprisingly find that the intestine also changes completely.
News • Inhibition of Sars-CoV-2 proliferation
New 'hairpin' tool stops coronavirus in its tracks
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
News • Inclusion of all cell lineages
Advanced pancreas organoid for better insights
A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.
News • Dermatology
Exploring fibroblast subtypes and skin cancer aggressiveness
New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.
News • Restoring antibacterial efficacy
New hydrogel helps overcome antibiotic resistance
In the laboratory, researchers increased the bactericidal effect of antibiotics 64-fold with the use of a new hydrogel. The material made the antibiotics effective even against resistant bacteria.
News • Insights into ribosome variants
What keeps antibiotic-resistant bacteria from taking over?
It would seem that developing antibiotic resistance would give bacteria an immense advantage over their non-resistant counterparts. So, why do they not become dominant? New research may provide an answer.
News • Blood vessel-like coating
New material to protect devices against blood clot formation
Protection against blood clots: A new material, designed to mimic blood vessels, could allow for safer use of devices like catheters, stents, blood-oxygenation machines and dialysis machines.
News • Tradefair programme overview
Don't miss: Hot issues, current trends and innovations at the Medica 2024 Labmed Forum
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
News • Tradefair programme overview
Don't miss: Trends and innovations at the Medica 2024 Health IT Forum
How can innovations help to master challenges and demands in healthcare? This central question will be addressed at the Medica Health IT Forum, an established part of the programme at the trade fair.
Article • Molecular meets digital
Single-cell multiplex imaging: a powerful tool for digital pathology
Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…
News • Microgravity-induced changes
How cancer cell cultures in space can help defeat cancer on Earth
New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.
News • Research on "double strike" mechanism
Induction of defective cell division could improve blood cancer therapy
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.
News • Catch some EVs
Liquid biopsy to improve cancer diagnosis
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
News • Finding the fibrils
The “superspreaders” behind Alzheimer's disease
Misfolded proteins lead to Alzheimer's disease – but where do they come from? Using a particularly powerful imaging technique, Swiss researchers now uncovered a key mechanism.
News • Insights into bile production
Liver discovery could lead to better CVD treatments
A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.
News • Radiopharmaceutical study
New mini-protein shows promise in targeted radiation delivery to tumors
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
News • New frontiers in imaging
First MRI in Antarctica to study brains in space
Magnetic resonance imaging (MRI) has made the jump to the Antarctic continent. A new mobile scanner at the Concordia research station is used to study effects on the brain even further away: in space.
News • From silent to destructive
Exploring the two phases of Alzheimer's disease
Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.
Sponsored • Innovation in action
Taipei showcases cutting-edge medical devices & diagnostics at Medica 2024
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
News • Research into protein structures
New research findings on the interaction of the three large protein complexes
How do the three large protein complexes – the ribosome, the SKI complex and the exosome – interact? A team of scientists led by Elena Conti reveals this question in their current study.
News • Hibernation
Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold
A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.
News • Gene Therapy
Innovative gene therapy for hemophilia
Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.
News • Brain cancer immunotherapy
Turning immune cells against glioblastomas
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
News • Hard to treat cancers
KRAS “degrader” could lead to treatment for millions of cancer patients
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
News • Groundwork for new treatments
Fibrosis a prognostic biomarker for HER2-negative breast cancer
A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.
News • AnWj blood group antigen
MAL: new blood group system discovered
Researchers identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of patients lacking this blood group.
News • Neurodegenerative diseases
Tauopathy or Alzheimer's? Biomarker and PET imaging for improved diagnosis
Researchers have identified biomarkers that, in conjunction with PET imaging, enable doctors to reliably distinguish between primary 4-repeat tauopathies and Alzheimer's disease.
News • When red means bad (for the heart)
Nutri-Score hints at foods that increase CVD risk
The Nutri-Score is designed to provide consumers with information on nutritional quality. New research reveals that the ratings also correspond with the cardiovascular health impact of the products.
News • Glioblastoma research
Brain scars from cancer treatment key factor for relapse
Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.
News • Thermal-responsive magnetic nanorobot collectives
Stopping brain bleeds from aneurysms with tiny robots
Brain aneurysms cause around 500,000 deaths globally each year and can lead to stroke and disability. Now, researchers created nanoscale robots to manage bleeds in the brain caused by aneurysms.
News • Dynamic network analysis
AI unlocks new path to personalized cancer treatments
A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.
News • Quicker, cheaper and less painful test
Blood crystals to reveal early signs of prostate cancer
A new method of analysing the crystals in dehydrated blood could lead to a quicker, cheaper and less painful technique to diagnose, early detect, and monitor prostate cancer.
News • MCMV based approach
Covid-19: vector vaccine offers long-term protection
Protection from established Covid-19 vaccines wanes relatively quickly. A new vector vaccine elicits prolonged immune response in animal models, and maintains its efficacy over extended time.
News • Neurometabolism
Huntington: New insights into disease progression
Researchers discovered a gene that might be a key factor in the progression of Huntington’s disease in organoids. The gene may contribute to brain abnormalities much earlier than previously thought.
News • Sars-CoV-2 research
Coronavirus produces 'dummy' proteins to fool the immune system
Brazilian researchers have identified a key mechanism of Sars-CoV-2 to manipulate its host’s immune defense. This discovery could pave the way for the development of novel therapies.
News • Focus on ILC immune cells
Research reveals cause for lupus kidney damage
Systemic lupus erythematodes can lead to severe kidney damage. However, until now, the cause for this remained unclear. New research has now revealed the underlying mechanism.
News • Promising research on oral rinse-based test
Wash, rinse – detect head and neck cancer?
Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.
News • Glycopeptide probes for antibody detection
New method speeds up pancreatic cancer detection
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
News • DTI for concussion patients
Advanced brain MRI to reveal ‘hidden disease’
Just a concussion? Head injury can lead to persistent symptoms, yet CT scans often fail to identify these cases. Researchers explore the potential of diffusion tensor imaging for better diagnostics.
News • Bioactive polymer scaffold
New biomaterial regrows damaged cartilage in joints
A crucial component in joints, cartilage is notoriously difficult to repair. Now, US researchers have developed a promising bioactive material to regenerate cartilage in knee joints.
News • Sticky, yet promising research
3D printing lung tissue from mucus-based bioink
Researchers have created a mucus-based bioink which can be used for 3D printing lung tissue. This advance could one day help study and treat chronic lung conditions.
News • Focus on Toxoplasma gondii
Could brain parasites help treat cognitive disorders?
Toxoplasma gondii is a parasite with the ability to infect the brain, causing life-threatening diseases. Researchers now want to harness its properties to advance treatment of cognitive disorders.
News • Synthetic nanofibers
Repairing cartilage damage with ‘dancing’ molecules
US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.
News • Tumor assessment via chromatin imaging
From DCIS to IDC: AI identifies breast cancer stages
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
News • Fluorescence assay
A 'FAIRY' to rapidly determine virus infectivity
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
News • Hydrogel solution
Breakthrough in fridge-free storage of medicines
Many medicines require cold storage, which is a challenge for infrastructure and sustainability. Now, researchers designed a hydrogel protecting therapeutics at temperatures as high as 50°C.
News • Immunology
“One and done”: promise for a universal influenza vaccine
New research reveals a promising approach to developing a universal influenza vaccine that confers lifetime immunity against an evolving virus considered most likely to trigger the next pandemic.
News • Biomaterial-based device
Heart valve made of human collagen opens up new treatment avenues
A new heart valve comprised of biological material obtained from human cells, opens up new therapeutic avenues for patients with paediatric heart diseases, such as tetralogy of Fallot.
News • Nanorobots travelling through synovial fluid
Fighting arthritis with “OrthoBots”
Enzyme-driven nanorobots could be used in the treatment of joint diseases such as arthritis. A new research project explores the potential of this technology.
News • Focus on microproteins
Researchers find potential target for liver cancer vaccine
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
News • HPV oncoprotein quantification
Urine test improves cervical cancer early detection
A new test shows promise in making cervical cancer screening more accessible and less invasive by detecting oncoproteins of the human papillomavirus (HPV) in urine samples.
News • Circulating tumor extracellular vesicles
Metastatic prostate cancer: better monitoring with new liquid biopsy method
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
News • Research on physical conditions
Exploring the link between obesity and cancer risk
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
News • The role of tissue stiffness
Pancreatic cancer: new approach could reverse chemo resistance
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
News • "Candycrunch"
AI and mass spectrometry to find cancer clues at lightning speed
Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.
News • Biomarkers enhance early detection
Parkinson's: blood test predicts disease up to seven years before symptoms
A novel blood test shows promise to predict Parkinson's disease in risk patients up to seven years before the typical motor symptoms appear.
News • Vital mechanism discovered
Promising approach to prevent breast cancer recurrence
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
News • Disturbed lipid metabolism
Charcot-Marie-Tooth: Researchers uncover impact of genetic cause
Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.
News • Antibacterial protein as therapeutic target
Pancreatic cancer: new approach for immunotherapy
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
Article • Pros and cons of diagnostic techniques
Liquid biopsy vs. tissue biopsy: Getting the best of both worlds
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
News • Axon vulnerability to damage
Male and female brains are different – and so are the effects of concussions
Structural differences in male and female brains might explain why women are more prone to concussions and experience longer recovery from the injury than men, according to a new preclinical study.
News • Hydrogel catalyst
Breaking down alcohol in the body: Researchers develop "detox gel"
Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.
News • Research on DNA danage
Surprise finding on cancer cell death to impact therapies
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
News • Vaccines for future pathogens
“We don’t have to wait for new coronaviruses to emerge”
A new approach to vaccine development could produce vaccines before the disease-causing pathogen – such as a new variant of the coronavirus Sars-CoV-2 – even emerges.
News • Quantum sensing prototype
A sensor that detects errors in MRI scans
A new sensor prototype can detect errors in MRI scans in a way that is impossible for current electrical sensors – and hopefully pave the way for MRI scans that are better, cheaper and faster.
News • Research on autoantibody patterns
The unique and complex origins of rheumatoid arthritis
New research challenges assumptions about the origin of rheumatoid arthritis, which are probably too simple. The findings may point towards improved diagnostics of this painful autoimmune disease.
News • On-demand reversibility
Anticoagulation with an ‘on/off’ switch
Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.
News • Gene-snipping bacterial defenses
CRISPR: a promising tool to fight antibiotic resistance, but...
Could the 'gene scissors' CRISPR be used to make resistant bacteria susceptible to first-line antibiotics again? According to new reseach, yes – but the experts also point out serious caveats.
News • Ciliopathy reseach
Rare lung disease: genetics reveals cause of PCD
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
News • MRSA and other infections
Researchers develop vaccine to fight antibiotic resistance
Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.
News • Researchers explore new treatment method
Using plasma irradiation to speed up bone healing
Aiming to shorten recovery times after a bone fracture, an Osaka Metropolitan University-led research group is focusing on plasma irradiation as a treatment method to speed up bone healing.
News • Research on biomechanics
Tumour 'softness' can drive aggressiveness of breast cancer
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
News • Research on syndrome correlation
Finding the link between Guillain-Barré and Takotsubo
Takotsubo cardiomyopathy (‘broken heart syndrome’) is a known complication of Guillain-Barré, but not much is known about the association between the two. New research aims to change this.
News • Mechanistic subtypes
The telltale traces long Covid leaves in the blood
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Article • Pharmaceutical research
Boosting biomarker detection with digital pathology
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
News • Promising secretory granules
New micromaterial to fight cancer with nanoparticle-targeting
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
News • Proof of Concept funding
New research to starve resistant bacteria
Researchers are developing novel active substances designed to cut off the nutrient supply of resistant bacteria, effectively starving them to death.
News • Tumor organoid platform
Personalized 3D bioprinting to advance gastric cancer treatment
Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.
News • Neurodegeneration
New insights on cause of brain calcification
Much like joints or blood vessels, the brain can be affected by calcifications. This can lead to neurodegenerative disease, but is not well studied. Now, researchers from Norway identified a gene that provides new insights.
News • Using portable devices
Lighting the way to noninvasive blood glucose monitoring
New research could revolutionize noninvasive monitoring of blood glucose levels (BGLs): a Japanese team developed a novel methodology to estimate BGLs from near-infrared light (NIR) measurements.
News • Research on Sars-CoV-2 antibody response
Study: Coronavirus infections last a long time (but so does vaccine protection)
New study results explore the long-term effects of infection with Sars-CoV-2, and challenge the idea that vaccine immunity fades quickly.
News • New antibodies discovered
Researchers snake toward a universal antivenom
Scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia.
News • Medication safety
Should these pills go together? ML model predicts drug interactions
Not all medication can safely be taken together. Using a machine-learning algorithm, researchers predict interactions that could interfere with a drug’s effectiveness.
News • Explanation for neurological symptoms
Coronavirus does not infect the brain, but...
How does a coronavirus infection cause neurological symptoms such as headaches, memory problems, and fatigue? A new study points to a different reason than previously assumed.
News • Pan-cancer proteogenomics
Characterizing the immune landscape in cancer
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
News • Focus on protein GDF15
Newfound mechanism could improve efficiency of diabetes treatments
Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.
News • Histological transformation
How lung cancer can transform into another type
Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.
News • Myelin visualisation
New MRI procedure makes multiple sclerosis visible
The loss of myelin sheaths in the brain is a hallmark of multiple sclerosis. Swiss researchers have now developed an MRI method that maps the condition of this nerve insulation layer more accurately.
News • Restoring responsiveness
New method could crack treatment-resistant prostate cancer
Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.
Article • Women's health
Osteoporosis and menopause: New measures to assess fracture risk
Bone fractures caused by osteoporosis are a common major global health risk. The International Osteoporosis Foundation (IOF) reports that one in three women over the age of 50 will sustain a potentially life-threatening fragility fracture in their remaining lifetimes. Early diagnosis and proactive treatment to keep bones healthy, including prescription medication and lifestyle changes, has the…
News • Elimination of senescent tumour cells
Study: Immunotherapy makes anti-cancer chemotherapy more efficient
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
News • Updated diagnostic criteria
Parkinson's: New three-type classification
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
News • Complication prevention
Placenta organoids help understand pre-eclampsia and pregnancy disorders
Using lab-grown ‘mini-placentas’, researchers from the UK and Switzerland hope to get new insights on dangerous pregnancy complications, such as pre-eclampsia.
News • Mammacarcinoma research
Study pinpoints breast cancer ‘cells-of-origin’ in high-risk women
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
News • Smart wound sealing
Soldering wounds with light and nano thermometers
A new soldering technique developed by Empa researchers is expected to prevent wound healing disorders and life-threatening complications from leaking sutures.
News • Urea-powered machines
Nanorobots to reduce bladder tumours by 90%
New research demonstrates how tiny nanomachines could greatly reduce bladder cancer by precisely targeting the tumour and attacking it with a radioisotope carried on their surface.
News • Promising study in mice
Exploring the potential of mRNA technology for rare diseases
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
News • Ultraviolet disinfection
Scientists discover how UV light destroys the coronavirus
Researchers from the University of Southampton investigated how ultraviolet laser light destroys the coronavirus Sars-CoV-2 by impacting components critical for infection.
News • Water exchange detection
New MRI-based method measures tumor malignancy
An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.
News • Point-of-care diagnostic platform
Inhalable sensors for early lung cancer detection
Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.
News • Promising approach
Researchers use nanodrones for targeted cancer treatment
A research team has successfully developed “NK cell-engaging nanodrones” capable of selectively targeting and eliminating cancer cells, offering a potential solution for intractable cancer types.
News • Raman spectroscopy
Novel bacteria identification methods to speed up disease diagnosis
A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
News • "Gene scissors" vs. sickle cell disease
FDA approves first CRISPR/Cas therapy
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
News • Cytokine reference
New “dictionary” reveals suprising complexity of immune responses
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
News • Synthetic biology
Artificial cells could be used in drug delivery, tissue engineering
Researchers have developed a simple, yet efficient way to create cell-like synthetic structures. These artificial cells could be used for a range of medical purposes – for example, in drug delivery.
Article • Knowledge gaps in gender medicine
Covid-19 and sex: higher mortality of male patients
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
News • Point-of-care neurodiagnosis
Eye-safe laser technology to diagnose traumatic brain injury
Researchers from the University of Birmingham have designed and developed a novel diagnostic device to detect traumatic brain injury (TBI) by shining a safe laser into the eye.
News • Troponin assessment
Blood test aids emergency diagnosis of heart conditions
A high sensitivity blood test can improve diagnosis for one in five patients who have a heart muscle injury, according to new research.
News • Ventricular fibrillation research
Promising therapeutic target for cardiac arrhythmias discovered
A newly discovered signaling mechanism implicated in the development of ventricular fibrillation offers promise of future treatment options for this life threatening condition.
News • Funcional brain imaging
New design increases fMRI resolution tenfold
Ten times more detail than current 7T scanners, over 50 times more than 3T: A new type of functional MRI will allow neuroscientists to more precisely localize and trace brain networks.
News • Stem cell research
Camouflaging transplants to avoid immune rejection
Researchers from the Chinese Academy of Sciences, Beijing, have genetically engineered stem cells so that liver cells obtained from them would be invisible to the immune system.
Article • Infection control
The strain typing technologies of tomorrow
Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.
News • Biosensor
Wireless, handheld device to detect Alzheimer’s and Parkinson’s biomarkers
A team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly.
Article • Latest advances
Lab-on-a-chip systems in 2023: The micro-lab revolution
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
News • PDAC subtype classification
Attacking the roots of pancreatic cancer
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
News • Prognostic model
New urine-based test offers hope for bladder cancer patients
In a new study, researchers from Fudan University have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.
News • Ultraviolet cell visualisation
'Seeing' cancer though the eyes of a butterfly
Inspired by the enhanced visual system of butterflies, researchers have developed an imaging sensor to “see” into the UV range for differentiating between cancer and normal cells.
News • VITT reseach
Cause for rare, but deadly vaccine-related blood clotting found
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
News • Good killer cells
Cellular immunotherapy: a new approach against cancer
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
