In the laboratory, researchers increased the bactericidal effect of antibiotics 64-fold with the use of a new hydrogel. The material made the antibiotics effective even against resistant bacteria.
It would seem that developing antibiotic resistance would give bacteria an immense advantage over their non-resistant counterparts. So, why do they not become dominant? New research may provide an answer.
Protection against blood clots: A new material, designed to mimic blood vessels, could allow for safer use of devices like catheters, stents, blood-oxygenation machines and dialysis machines.
Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.
How can innovations help to master challenges and demands in healthcare? This central question will be addressed at the Medica Health IT Forum, an established part of the programme at the trade fair.
New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
Misfolded proteins lead to Alzheimer's disease – but where do they come from? Using a particularly powerful imaging technique, Swiss researchers now uncovered a key mechanism.
A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.
A ‘mini-protein’ can deliver radiation doses directly to tumours without harming healthy tissues. The approach shows promise for the treatment of metastatic bladder cancer and other tumours.
Magnetic resonance imaging (MRI) has made the jump to the Antarctic continent. A new mobile scanner at the Concordia research station is used to study effects on the brain even further away: in space.
Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
How do the three large protein complexes – the ribosome, the SKI complex and the exosome – interact? A team of scientists led by Elena Conti reveals this question in their current study.
A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.
Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.
Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue.
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.
Researchers identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of patients lacking this blood group.
Researchers have identified biomarkers that, in conjunction with PET imaging, enable doctors to reliably distinguish between primary 4-repeat tauopathies and Alzheimer's disease.
The Nutri-Score is designed to provide consumers with information on nutritional quality. New research reveals that the ratings also correspond with the cardiovascular health impact of the products.
Researchers have identified fibrotic scarring as a key source of resurgence of glioblastoma multiforme (GBM). The new insights could lead to better prevention of this type of brain cancer.
Brain aneurysms cause around 500,000 deaths globally each year and can lead to stroke and disability. Now, researchers created nanoscale robots to manage bleeds in the brain caused by aneurysms.
A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.
A new method of analysing the crystals in dehydrated blood could lead to a quicker, cheaper and less painful technique to diagnose, early detect, and monitor prostate cancer.
Protection from established Covid-19 vaccines wanes relatively quickly. A new vector vaccine elicits prolonged immune response in animal models, and maintains its efficacy over extended time.
Researchers discovered a gene that might be a key factor in the progression of Huntington’s disease in organoids. The gene may contribute to brain abnormalities much earlier than previously thought.
Brazilian researchers have identified a key mechanism of Sars-CoV-2 to manipulate its host’s immune defense. This discovery could pave the way for the development of novel therapies.
Systemic lupus erythematodes can lead to severe kidney damage. However, until now, the cause for this remained unclear. New research has now revealed the underlying mechanism.
Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
Just a concussion? Head injury can lead to persistent symptoms, yet CT scans often fail to identify these cases. Researchers explore the potential of diffusion tensor imaging for better diagnostics.
A crucial component in joints, cartilage is notoriously difficult to repair. Now, US researchers have developed a promising bioactive material to regenerate cartilage in knee joints.
Researchers have created a mucus-based bioink which can be used for 3D printing lung tissue. This advance could one day help study and treat chronic lung conditions.
Toxoplasma gondii is a parasite with the ability to infect the brain, causing life-threatening diseases. Researchers now want to harness its properties to advance treatment of cognitive disorders.
US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
Many medicines require cold storage, which is a challenge for infrastructure and sustainability. Now, researchers designed a hydrogel protecting therapeutics at temperatures as high as 50°C.
New research reveals a promising approach to developing a universal influenza vaccine that confers lifetime immunity against an evolving virus considered most likely to trigger the next pandemic.
A new heart valve comprised of biological material obtained from human cells, opens up new therapeutic avenues for patients with paediatric heart diseases, such as tetralogy of Fallot.
Enzyme-driven nanorobots could be used in the treatment of joint diseases such as arthritis. A new research project explores the potential of this technology.
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
A new test shows promise in making cervical cancer screening more accessible and less invasive by detecting oncoproteins of the human papillomavirus (HPV) in urine samples.
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.
A novel blood test shows promise to predict Parkinson's disease in risk patients up to seven years before the typical motor symptoms appear.
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
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Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
Structural differences in male and female brains might explain why women are more prone to concussions and experience longer recovery from the injury than men, according to a new preclinical study.
Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
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A new approach to vaccine development could produce vaccines before the disease-causing pathogen – such as a new variant of the coronavirus Sars-CoV-2 – even emerges.
A new sensor prototype can detect errors in MRI scans in a way that is impossible for current electrical sensors – and hopefully pave the way for MRI scans that are better, cheaper and faster.
New research challenges assumptions about the origin of rheumatoid arthritis, which are probably too simple. The findings may point towards improved diagnostics of this painful autoimmune disease.
Researchers developed a new type of anticoagulant whose action can be rapidly stopped. This reversible activity could revolutionise the use of anticoagulants in surgery or other applications.
Could the 'gene scissors' CRISPR be used to make resistant bacteria susceptible to first-line antibiotics again? According to new reseach, yes – but the experts also point out serious caveats.
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.
Aiming to shorten recovery times after a bone fracture, an Osaka Metropolitan University-led research group is focusing on plasma irradiation as a treatment method to speed up bone healing.
Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.
Takotsubo cardiomyopathy (‘broken heart syndrome’) is a known complication of Guillain-Barré, but not much is known about the association between the two. New research aims to change this.
Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
A newly-developed material made of proteins shows promise for targeted cancer therapies: Like secretory granules in the endocrine system, it delivers nanoparticles which attack specific cancer cells.
Researchers are developing novel active substances designed to cut off the nutrient supply of resistant bacteria, effectively starving them to death.
Using 3D bioprinting to accurately replicate the biological environment surrounding gastric cancer cells, researchers predicted a patient’s response to anticancer drugs during the preclinical stage.
Much like joints or blood vessels, the brain can be affected by calcifications. This can lead to neurodegenerative disease, but is not well studied. Now, researchers from Norway identified a gene that provides new insights.
New research could revolutionize noninvasive monitoring of blood glucose levels (BGLs): a Japanese team developed a novel methodology to estimate BGLs from near-infrared light (NIR) measurements.
New study results explore the long-term effects of infection with Sars-CoV-2, and challenge the idea that vaccine immunity fades quickly.
Scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia.
Not all medication can safely be taken together. Using a machine-learning algorithm, researchers predict interactions that could interfere with a drug’s effectiveness.
How does a coronavirus infection cause neurological symptoms such as headaches, memory problems, and fatigue? A new study points to a different reason than previously assumed.
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.
Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.
The loss of myelin sheaths in the brain is a hallmark of multiple sclerosis. Swiss researchers have now developed an MRI method that maps the condition of this nerve insulation layer more accurately.
Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.
Bone fractures caused by osteoporosis are a common major global health risk. The International Osteoporosis Foundation (IOF) reports that one in three women over the age of 50 will sustain a potentially life-threatening fragility fracture in their remaining lifetimes. Early diagnosis and proactive treatment to keep bones healthy, including prescription medication and lifestyle changes, has the…
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
Using lab-grown ‘mini-placentas’, researchers from the UK and Switzerland hope to get new insights on dangerous pregnancy complications, such as pre-eclampsia.
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
A new soldering technique developed by Empa researchers is expected to prevent wound healing disorders and life-threatening complications from leaking sutures.
New research demonstrates how tiny nanomachines could greatly reduce bladder cancer by precisely targeting the tumour and attacking it with a radioisotope carried on their surface.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
Researchers from the University of Southampton investigated how ultraviolet laser light destroys the coronavirus Sars-CoV-2 by impacting components critical for infection.
An Italian research team has introduced a new MRI-based method for assessing water water exchange to estimate the degree of malignancy and the success of treatments in tumors.
Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.
A research team has successfully developed “NK cell-engaging nanodrones” capable of selectively targeting and eliminating cancer cells, offering a potential solution for intractable cancer types.
A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
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Researchers have developed a simple, yet efficient way to create cell-like synthetic structures. These artificial cells could be used for a range of medical purposes – for example, in drug delivery.
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
Researchers from the University of Birmingham have designed and developed a novel diagnostic device to detect traumatic brain injury (TBI) by shining a safe laser into the eye.
A high sensitivity blood test can improve diagnosis for one in five patients who have a heart muscle injury, according to new research.
A newly discovered signaling mechanism implicated in the development of ventricular fibrillation offers promise of future treatment options for this life threatening condition.
Ten times more detail than current 7T scanners, over 50 times more than 3T: A new type of functional MRI will allow neuroscientists to more precisely localize and trace brain networks.
Researchers from the Chinese Academy of Sciences, Beijing, have genetically engineered stem cells so that liver cells obtained from them would be invisible to the immune system.
Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.
A team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly.
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
In a new study, researchers from Fudan University have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.
Inspired by the enhanced visual system of butterflies, researchers have developed an imaging sensor to “see” into the UV range for differentiating between cancer and normal cells.
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
Chemotherapy, radiotherapy or surgery – these are the three common forms of cancer therapy. Now, lymphoma specialists in Essen are investigating the possibility of a different approach.
Researchers from Osaka University present a novel technique to detect different coronavirus variants quickly, including fast-spreading strains present in human saliva.
Chronic wounds in diabetes patients are often slow to heal, which can lead to serious infections and even limb amputation. Now, researchers propose to address this with a magnetic wound-healing gel.
A new study found that the antibody response of infants and young children against Sars-CoV-2 deviates from that of adults in a small, but very significant way.
University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.
What role should artificial life play in medicine? Researchers from Denmark and the US explore the potential of hybrid peptide-DNA nanostructures for diagnosing and treating diseases.
A European team of researchers have successfully developed a new, living organ model which could advance rapid testing of new or common drugs to treat diseases of the liver.
A team of researchers from Vienna has discovered that dormant breast cancer tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein.
Researchers in Spain have developed a system using patient cells which represents the first 3D muscle model capable of replicating the damage caused by Duchenne muscular dystrophy (DMD).
Researchers at the University of Michigan have zeroed in on Candida auris – a fungus with the uncanny ability to stick to everything from skin to catheters – and made a startling discovery.
Researchers from Rutgers University developed a way to help hospitals identify life-threatening Covid-19 cases using machine-learning software. The algorithm identified six crucial parameters.
A new class of antibiotics, based on proven drugs used in cancer treatment, is now being developed by researchers at Linköping University. They could be used against resistant bacteria.
Could a single biomarker detect all types of diseases related to dopamine deficiency in the brain? According to a Swedish research group, such a marker may have just been found.
Swiss scientists report that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across spinal cord injuries and guide nerves to reconnect to their natural targets.
New methods to predict outcomes for pregnancies where there are issues with poor growth of the baby inside the womb have been developed by a team of scientists.
A new onco-therapeutic vaccine candidate against human papillomavirus (HPV)-induced cancers, such as cervical and oropharyngeal cancers, has shown promising results in the preclinical phase.
Engineers from MIT are developing a device containing insulin-producing cells and a tiny oxygen-producing factory to keep the cells of diabetes patients healthy.
A newly discovered mechanism involving exosomes can drive inflammation and impair healing of wounds in diabetes patients, according to a new study led by University of Pittsburgh and UPMC researchers.
A new research breakthrough could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis.
It had long been recognized that the brain was made up of two types of cells, neurons and glial cells. Now, neuroscientists discovered an additional type - with huge implications for brain disorders.
Researchers in France identified changes to the immune memory after infection with the Omicron BA.1 variant in thrice-vaccinated patients. The remodeling actually works to the patients' benefit.
A team from Geneva demonstrates the value of imaging to detect the presence of tau protein in the brain to predict cognitive decline due to Alzheimer’s disease.
German bioinformaticians have now detected an unexpected diversity of certain cell appendages in the bacterium Acinetobacter baumannii that are associated with its pathogenicity.
ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia: beta thalassaemia and sickle cell anaemia.
An 'encyclopaedia' of protein alterations in soft tissue sarcomas could open the door to a new era of understanding and treatment for this group of rare cancers.
Scientists have developed a tool to create a digital replica of an individual's heart, which could inform the diagnosis and treatment of cardiovascular diseases.
Combining aerosol sampling and ultrasensitive biosensing, researchers have created a real-time monitor that can detect any of the Sars-CoV-2 virus variants in a room in about 5 minutes.
A new publication discusses deep-ultraviolet (DUV) photonics for the disinfection of Sars-CoV-2 and its variants (Delta and Omicron) in the cryogenic environment.
Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.
A research team from Barcelona studied the liver of Alzheimer's disease mice models, and demonstrated the importance of the liver-brain axis regarding the psychological symptoms of the disease.
A gel that combines both stiffness and toughness is a step forward in the bid to create biodegradable implants for joint injuries, according to new research from the University of British Columbia.
To ensure that wounds remain tightly sealed in the abdomen after surgery, researchers at Empa and ETH Zurich have developed a patch with a sensor function.
Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…
US researchers identified a potential breakthrough in glioblastoma treatment. Using a modified virus, they created a treatment that specifically attacks tumor cells, while leaving normal cells intact.
Unanswered questions are hampering clinicians in their efforts to get the best out of a precision medicine approach for their patients. Speaking at the Genomics and Precision Medicine Expo in London at the end of May, cancer educator Dr Elaine Vickers said the benefits of being matched to an investigational drug remain questionable for most people with advanced cancer.
Damage to the brains of patients operated on for brain tumors may be assessed by measuring biomarkers in the blood pre- and postoperatively, a new study from the University of Gothenburg shows.
Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
Researchers at Karolinska Institutet have found further evidence for how the Epstein-Barr virus (EBV) can trigger multiple sclerosis (MS) or drive disease progression.
An algorithm developed using artificial intelligence could soon be used by doctors to diagnose heart attacks with better speed and accuracy than ever before, according to new research.
Researchers at the University of Helsinki have demonstrated that certain strains of Desulfovibrio bacteria are the likely cause of Parkinson’s disease in most cases.
Dutch scientists have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer.
A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.
Getting vaccines to people who need them isn't always easy. Many vaccines require cold storage, making it difficult to ship them to remote areas that don't have the necessary infrastructure.
Autism spectrum disorder (ASD) is a developmental disorder associated with difficulties in interacting with others, repetitive behaviors, restricted interests and other symptoms that can impact academic or professional performance.
Neurodegeneration, or the gradual loss of neuron function, is one of the key features of Alzheimer's disease. However, it doesn't affect all parts of the brain equally.
Genes are full of clues about a person's health and might also show the way for stroke recovery.
A new artificial intelligence model could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer.
Researchers at the University of Campinas and the Federal University of São Carlos in Brazil have developed an electrochemical sensor that detects Parkinson's disease at different stages.
Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors: Cisplatin is used successfully in the chemotherapy of testicular cancer.
Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.
A research team from DGIST develops an electronic medicine technology that restores abnormal protein behavior, the cause of Charcot-Marie-Tooth Disease (CMT).
A new study led by the University of Edinburgh has identfied areas of the brain susceptible to damage from high blood pressure, affecting memory loss, thinking skills and dementia.
US scientists report using a single-atom-thick nanomaterial to simultaneously detect Covid-19 and flu viruses — at much lower levels and much more quickly than conventional tests for either.
Chemotherapy resistance is a main cause of treatment failure and death in cancer patients. Researchers from Brussels found how cancer cells protect themselves from the aggressive treatment.
For pancreatic cancer, the effect of immunotherapy is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this sex difference.
Scientists have discovered why breast cancer cells that have spread to the lungs may ‘wake up’ following years of sleep - forming incurable secondary tumours.
French scientists are developing and testing a new vaccine to combat allergic asthma. Their latest study results pave the way for the organization of a clinical trial.
Researchers at the Universitat Autònoma de Barcelona (UAB) have developed a new type of nanoparticles inspired by the structure of amyloids, capable of neutralising the SARS-CoV-2 virus.
Researchers in Frankfurt have now been able to show how ferroptosis can be used to make immunotherapies against liver cancer more effective in mice.
Scientists are developing a new kind of light-activated cancer treatments. This would work by switching on LED lights embedded close to a tumour, which would then activate biotherapeutic drugs.
In a world first, scientists from Singapore and Germany have shown that regenerative therapy to restore impaired kidney function may soon be a possibility.
Combining single-cell data with a self-learning algorithm reveals how structural changes in chromosomes can trigger cancer. This could pave the way for personalized cancer treatments.
High-intensity focused ultrasound (HIFU) ablation is a noninvasively treatment for benign thyroid nodules that are causing distress to patients. Brian H. H. Lang, MD, Clinical Professor in the Department of Surgery at the University of Hong Kong, and chief of the Division of Endocrine Surgery at Queen Mary Hospital, is a preeminent investigator, proponent, and pioneer of this technique. He…
Canadian researchers are developing a new, ultra-sensitive biosensor to screen for Alzheimer’s disease and other diseases. The device has successfully completed the proof-of-concept stage.
Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.
A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research.
Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
New research shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. This could improve diagnosis and treatment of uterine cancer.
In a recent study, a US research team developed a revolutionary laser-based approach to perform microbiopsies. Their novel method could make biopsies faster, more cost-effective, and less harmful to the patient.
How does the coronavirus actually work? Dutch researchers have produced an animated video to visualise the life cycle of the virus using real-life microscopic images of infected cells.
Researchers have developed a so-called “heart attack on a chip”, which could one day serve as a testbed to develop new heart drugs and even personalized medicines.
Scientists from Singapore discovered a novel low-cost method of testing for cancers. The test sequences heated clinical samples to isolate cancer-specific signatures found in a patient’s blood.
An international team highlights the importance of localising BRCA1 and BRCA2 gene mutations for the treatment of ovarian cancer.
For the first time, a new study has identified enlarged perivascular spaces in the brains of migraine sufferers. Results of the study will be presented at the annual RSNA meeting.
At this year's Medica tradefair, laboratory medicine, medical technology and life sciences give new impulses to the entire healthcare market - especially in times of the corona pandemic. An overview.
Speed or accuracy? As far as Covid-19 tests go, this was the choice you had to make. In the future, this dilemma could be a thing of the past.
Imagine, one single standardising solution, enabling uncompromisingly fast results and providing you with the exact same predictable turnaround time.
The risk of developing breast cancer is higher in breasts with high density. But why is that? Researchers at Linköping University have shown major biological differences that promote cancer growth.
With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.
Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.
Research presented in a new preprint suggests that SARS-CoV-2 might have been artificially created in a laboratory. Experts from Würzburg have reviewed the paper – and remain unconvinced.
Some leukemias evade treatment by changing their appearance and identity through changing the read-out of their DNA, a new study has found.
Researchers in Finland have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumours.
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
A vaccine design approach that could protect against new variants of SARS-CoV-2 but also potentially protects against other coronaviruses is one step closer to reality as a result of new research.
Treatment of central nervous system diseases and tumors is often hindered by the blood-brain barrier. A new method aims to overcome this obstacle using focused ultrasound intranasal delivery (FUSIN).
Researchers mapped in detail how the immune system acts against pathogens invading the brain. This sheds new light on host-pathogen interactions and the long-term consequences of brain infections.
Researchers have shown that when brain cells are directly exposed to blood taken from Covid-19 patients with delirium, there is an increase in cell death and a decrease in the generation of new brain cells.
Scientists in Italy discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells. They also devised an experimental therapy to bypass or prevent this.
Researchers at Lund University in Sweden and Skåne University Hospital have conducted an animal study bringing hope that more donor lungs could be used in the future.
A research team has investigated how contrast agents disperse inside cells. This could improve the assessment and further development of these agents and contribute to future medical diagnostics.
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
A newly developed capsule that tunnels through mucus in the GI tract could be used to orally administer large protein drugs such as insulin.
A research group has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.
A new device for diagnosing bone fragility invented by the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE) has been approved for marketing in the European Economic Area and Switzerland. The device is based on a new approach to assessing bone quality via blood sampling.
The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team now showed that EVI1's cancer causing effect relies on activating a single gene — the stem cell transcription factor ERG.
Alveolar rhabdomyosarcoma is a rare pediatric tumor. For more than 40 years there has not been any new development regarding treatment. Research led by Prof. Dr. Anton Henssen at Charité University Berlin has now identified a new therapeutic option, using a drug that is currently under investigation for other types of cancer.
UC San Francisco researchers have developed a drug marking cancer cells for destruction by the immune system.
How can rapid antigen tests be adjusted to reliably detect future variants of SARS-CoV-2? A research team funded by the National Institutes of Health is currently working on finding an answer.
A new study led by researchers in Barcelona has determined the protein TIMP-1 as a valuable biomarker for the progression of lung adenocarcinoma. The results open the door to new treatments.
Researchers at Nottingham Trent University and Nottingham University Hospitals NHS Trust have developed a new biosensor capable of accurately monitoring the condition of a chronic wound.
An animal study brings hope that more donor lungs could be used in the future. The researchers have launched a pilot study to investigate whether the treatment will have the same positive effects on human beings.
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
Novel 3D imaging could comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease.
The interplay between the patient’s BMI, tumour size and cancer-specific proteins is of importance for the prognosis of breast cancer, a study from Sweden shows.
A considerable proportion of patients suffering from cancer of unknown primary (CUP) could benefit from comprehensive molecular analysis and molecularly-informed targeted therapies.
Researchers at McMaster University create device to replicate conditions in blood vessels after grafts.
The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.
Researchers identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches.
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
The development of a simple blood test for glioblastomas could mean earlier diagnosis and more effective and personalised treatment options against the most common type of malignant brain cancer.
Researchers have developed adeno-associated virus variants that target heart muscle cells and can thus be used for the precise treatment of heart diseases.
Researchers propose a new Covid-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies - a promising alternative for people with a weakened immune system.
An advanced form of cardiac MRI has for the first-time enabled clinicians to measure the effectiveness of chemotherapy in patients with the life-limiting condition ‘stiff heart syndrome’.
A sensor identifies misfolded protein biomarkers in the blood. This offers a chance to detect Alzheimer's disease before any symptoms occur. Researchers intend to bring it to market maturity.
Researchers in Sweden have now discovered a faster and easier way to determine who has an aggressive form of prostate cancer, and who has not.
Researchers have been able to produce antibodies to the SARS-CoV-2 spike protein in hen eggs. Antibodies harvested from eggs might be used to treat Covid-19 or as a preventative measure.
By recreating the helical structure of heart muscles, bioengineers improve understanding of how the heart beats.
Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease, researchers found.
A new type of vaccine provides protection against a variety of SARS-like betacoronaviruses, including SARS-CoV-2 variants, in mice and monkeys, according to a new study.
Research team led by Göttingen University combine two techniques to achieve isotropic super-resolution imaging.
To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.
The speedy, high-tech method of inexpensive, accurate and high-throughput protein biomarker assay testing is being touted as a much-needed development in point-of-care (PoC) testing.