Staphylococcus aureus is a leading cause of hospital-acquired bacterial infection, associated with over one million deaths worldwide each year. Now, researchers could be one step closer to a vaccine.
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
A new test shows promise in making cervical cancer screening more accessible and less invasive by detecting oncoproteins of the human papillomavirus (HPV) in urine samples.
Integrating bacterial genomic data with detailed human mobility data makes it possible to see how pathogens causing pneumonia and meningitis, move between regions and evolve over time.
A new approach to vaccine development could produce vaccines before the disease-causing pathogen – such as a new variant of the coronavirus Sars-CoV-2 – even emerges.
TikTok has become a go-to platform for young people seeking answers – including health information. But how accurate are the medical ‘Toks’? A new study analyzed the quality of the content.
Antimicrobial-resistant infections have become a global threat, with an annual death toll of over 1 million. Now, reseachers created a promising vaccine candidate for antibiotic-resistant bacteria.
The world has hardly processed Covid-19, so the thought of another pandemic is far from pleasant. Yet, infectious disease experts have picked the most likely candidate in a new survey.
New research provides cause for optimism that long Covid can resolve over time. Following people from the first wave of Covid-19, it monitored the longevity of immune abnormalities after an infection.
A recent suggestion to stop using the term ‘long-Covid’ may have been well-intentioned, but could ultimately do more harm than good, experts point out.
Patients who are suffering from aftereffects of a coronavirus infection often receive the diagnosis 'long Covid'. However, new research presented at ECCMID 2024 calls that term into question.
New study results explore the long-term effects of infection with Sars-CoV-2, and challenge the idea that vaccine immunity fades quickly.
Scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
A new, large-scale study from Sweden underlines the importance of vaccination against Covid-19: The research shows that an infection raises the risk of heart rhythm disturbances.
Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.
Being overweight – not just being obese – can increase Covid-19 severity. the elevated BMI creates an impaired antibody response to SARS-CoV-2 infection but not to vaccination, new research finds.
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
The Wallonia Export & Investment Agency welcomes the entire spectrum of the MedTech Industry on the Belgium Pavilion at Medica 2023 (Nov 13-16).
Sure, AI still has a long way go. But maybe one day in the not-so-distant future, AI will provide us with information about our current state of health, such as the number of red blood cells, cholesterol levels, fat percentage, and how many seconds last night's beer will shorten our life expectancy.
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
What does the future of the coronavirus look like? An international research team from Cologne and New York has developed a model to predict the likely evolution of Sars-CoV-2.
A new study found that the antibody response of infants and young children against Sars-CoV-2 deviates from that of adults in a small, but very significant way.
What role should artificial life play in medicine? Researchers from Denmark and the US explore the potential of hybrid peptide-DNA nanostructures for diagnosing and treating diseases.
New research from Copenhagen University Hospital – Rigshospitalet and Herlev and Gentofte Hospital has shed new light on the immune system’s complex struggle against the coronavirus.
For their contributions to developing mRNA vaccines to fight Covid-19, Katalin Karikó, PhD, and Drew Weissman, MD, PhD, have been jointly awarded the 2023 Nobel Prize in Physiology or Medicine.
Researchers from Rutgers University developed a way to help hospitals identify life-threatening Covid-19 cases using machine-learning software. The algorithm identified six crucial parameters.
A new onco-therapeutic vaccine candidate against human papillomavirus (HPV)-induced cancers, such as cervical and oropharyngeal cancers, has shown promising results in the preclinical phase.
Two out of the four screening tools used by emergency medical services are inadequate for recognising sepsis, according to new research presented at the EUSEM Congress.
Two new studies based on a large-scale cohort in Denmark explored the side effects of the coronavirus vaccine – one focused on acute effects, the other on a women's health issue.
Patients with immunodeficiency cannot benefit from conventional Covid-19 vaccines and still at risk from infection. A promising new approach now brings hope for this patient group.
Researchers in France identified changes to the immune memory after infection with the Omicron BA.1 variant in thrice-vaccinated patients. The remodeling actually works to the patients' benefit.
A family physician at Tufts University School of Medicine offers advice for how to treat allergies and how to tell if symptoms are due to allergies, the common cold, the flu, or Covid-19.
Do coronavirus vaccines skew the menstrual cycle, cause more bleeding or pain? Anecdotal reports hint at a connection. Now, a new study led by Boston University provides answers.
Research by the University of Southampton has shown that repeated Covid-19 vaccination increases the ability of lymphoma patients to prevent infection from the virus, particularly after four doses.
Missing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers’ technology for making time-released drugs.
German researchers have now investigated whether there is a temporal association between infection with the Sars-CoV-2 virus and the development of type 1 diabetes.
Protection offered by Covid-19 vaccination declines more rapidly in people with severe obesity than in those with normal weight, scientists at the Universities of Cambridge and Edinburgh have found.
Getting vaccines to people who need them isn't always easy. Many vaccines require cold storage, making it difficult to ship them to remote areas that don't have the necessary infrastructure.
Messenger Ribonucleic Acid (mRNA) as a therapeutic approach is gaining momentum due to its ability to be rapidly manufactured and its promising outcomes.
As ChatGPT becomes more popular among those seeking health advice, researchers try to find out whether the information provided by the AI chatbot is reliable and accurate.
Among all but oldest age groups, the US has higher death rates than five high-income European nations, according to new UCLA research. However, this gap is only partly due to Covid-19.
New research suggests most people don’t understand the difference between a preprint and a published academic journal article. Here is the distinction between the two – and why it is important.
French scientists are developing and testing a new vaccine to combat allergic asthma. Their latest study results pave the way for the organization of a clinical trial.
A new mathematical model developed by Hokkaido University engineers uses wastewater samples to effectively forecast the number of clinical Covid-19 cases in a community five days in advance.
The European Football Championship in 2021 had an impact on the participating countries' coronavirus infections, a new study shows. However, the extent depended greatly on the initial situation.
A novel imaging agent can reduce the number of false-positive PET/CT findings among cancer patients recently vaccinated for Covid-19. This may mitigate the issue of tracer uptake in lymph nodes associaed with the vaccine.
A new study has found that antibodies produced in the nose decline nine months after Covid-19 infection, while antibodies found in the blood last at least a year.
Covid-19 vaccinations that combine two or more distinct variants of SARS-CoV-2 could offer protection against current and future ‘variants of concern’, say scientists from UK and Austria.
There is no evidence of higher risk of miscarriage or ectopic pregnancy following vaccination against Covid-19 or infection with the disease, according to a new study.
At this year's Medica tradefair, laboratory medicine, medical technology and life sciences give new impulses to the entire healthcare market - especially in times of the corona pandemic. An overview.
Until now, it was feared that vaccination against Covid-19 could reduce the success of treatment for patients with nasopharyngeal cancer. A recent study now gives the all-clear in this regard.
Researchers from Barcelona report that vaccination with senescent cells shows promise in experimental models of melanoma and pancreatic cancer.
Despite treatment, chronic lung diseases such as COPD or cystic fibrosis can become so severe that a lung transplant is necessary. Dr Urte Sommerwerck explains which patients might be considered for transplantation and why follow-up is as important as the surgery itself.
The coronavirus pandemic caused by SARS-CoV-2 and its variants is still a major public safety issue worldwide. The “alpha” variant B.1.1.7, the “gamma” variant P.1, the “beta” variant B.1.351, and the “delta” variant B.1.617 are of particular concern because of their high prevalence. Large-scale vaccination and sensitive detection are vital for preventing the spread of Covid-19.
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
A vaccine design approach that could protect against new variants of SARS-CoV-2 but also potentially protects against other coronaviruses is one step closer to reality as a result of new research.
Covid-19 has led to global mortality changes unprecedented in the last 70 years, according to new research. However, the drop in life expectancy is not equally high in all countries.
A study in Japan finds antibody response to the Moderna Covid-19 mRNA vaccine does not vary depending on the time of day when the dose was received.
Referrals to Cambridge’s long Covid clinic fell dramatically in the period August 2021 to June 2022, which researchers say is likely due to the successful rollout of the vaccine.
It’s widely known that more than 70% of today’s medical decisions involve the results of laboratory tests, but the insights clinicians derive from these tests today may only be scratching the surface of their potential.
As the monkeypox outbreak continues to spread around the globe, a rare but potentially serious complication of the virus has been discovered.
What will the next pandemic look like? Health officials from across the globe gathered in Geneva in late August at a World Health Organization meeting to focus on how lessons learned from Covid-19 might best prepare civilization for the "next one."
Using a newly launched, comprehensive monkeypox registry, health professionals can share data on the skin symptoms of monkeypox and the vaccine to improve patient care.
Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.
Vaccination projects across the world are at a pivotal post-Covid moment, according to one of the leading experts in the field. Speaking to Healthcare in Europe ahead of the World Innovation Summit for Health (WISH) congress in Qatar – where vaccination will be a central topic – Dr Jerome Kim said there is an urgent need to regain a ‘positive consensus’ around the value of vaccines. He…
The overall risk of myocarditis is substantially higher immediately after being infected with Covid-19 than it is in the weeks following vaccination for the coronavirus, a large new study shows.
New diagnoses of disorders including psychosis, dementia, seizures and ‘brain fog’ remain commoner two years after Covid-19 than after other respiratory infections, new research finds.
A lack of high quality, up to date clinical guidance on monkeypox may be hampering effective and safe treatment of the infection around the world, a new review finds.
The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
Researchers propose a new Covid-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies - a promising alternative for people with a weakened immune system.
Researchers have been able to produce antibodies to the SARS-CoV-2 spike protein in hen eggs. Antibodies harvested from eggs might be used to treat Covid-19 or as a preventative measure.
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from Geneva reveals the exceptional capacity of Omicron to evade our immunity.
A new type of vaccine provides protection against a variety of SARS-like betacoronaviruses, including SARS-CoV-2 variants, in mice and monkeys, according to a new study.
To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.
Scientists shared one of the first high-resolution looks at the rabies virus glycoprotein in its vulnerable 'trimeric' form, revealing potential vaccine targets.
Over the last 50 years, malaria parasites have developed resistance to seven drugs, but a new way to identify future antimalarials holds promise.
Researchers have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.
Two years after infection with COVID-19, half of patients who were admitted to hospitals still have at least one symptom, according to the longest follow-up study to date.
The search for rare mutations in bacterial genome could lead to better diagnostics and treatments – reducing morbidity caused by the deadly disease.
A method for delivering genetic material to the body that has proven useful in Covid-19 vaccination is now being tested as a way to repair damaged heart muscle after a heart attack.
Climate change and antimicrobial resistance (AMR) are forming an alarming alliance: Global warming creates new breeding grounds for resistant bacteria. A serious and very real threat to public health – but not quite the doomsday scenario some might make it out to be, says Prof Sabiha Essack from the University of KwaZulu-Natal in Durban, South Africa.
Cedars-Sinai physician-scientists are pioneering imaging techniques and investigating new biomarkers to improve multiple sclerosis (MS) diagnosis and treatment.
By comparing the infectious viral load caused by ancestral SARS-CoV-2 as well as by the Delta and Omicron variants, scientists highlight the benefits of vaccination.
A new study enables developers to determine vaccine safety via smart sensors that measure objective physiological parameters. This could end the reliance on subjective reports of study participants.
A platform for studying how the human immune system responds to hepatitis C infection by combining microfluidic technology with liver organoids could speed the hunt for a vaccine.
Researchers have found another long-term complication associated with Covid-19 infections: peripheral neuropathy during and following their bouts with the virus.
An ECRC research team has introduced CRISPR-Cas9 into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.
The tool has made it possible to detect SARS-CoV-2 in exudate from symptomatic patients with a sensitivity of 100% and a specificity of 87.5%
A new study offers hope against liver cancer: A vaccine proved to be safe and effective protection in premalignant and malignant liver diseases in preclinical mouse models.
A new UK review shows that people who have had one or more doses of a coronavirus vaccine are less likely to develop long Covid than those who remain unvaccinated.
Is the Underground a safe means of transport in times of Covid-19? A computer simulation, developed at the University of Leeds, has calculated the infection risk.
Scientists have confirmed that an inhaled form of COVID vaccine can provide broad, long-lasting protection against the original strain of SARS-CoV-2 and variants of concern.
RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based compounds is far from being fully tapped, as RNA allows for entirely new therapeutic approaches.
Professor Richard Neher from the Biozentrum of the University of Basel is using his Nextstrain platform to investigate which variants of the SARS-CoV-2 virus are currently circulating worldwide.
Researchers from Charité – Universitätsmedizin Berlin and Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) present new findings on the immune response against SARS-CoV-2.
A new study shows that the SARS-CoV-2 Omicron variant is less effective than Delta at blocking a cellular defence mechanism against viruses, the so-called 'interferon response'.
How long can Covid-19 antigen tests reliably tell the antibody status? Researchers at the Paul-Ehrlich-Institut identified several factors that affect the detection duration.
A connection between the Epstein-Barr virus and multiple sclerosis has long been suspected. A new study provides ‘compelling evidence of causality’.
An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants.
The Omicron variant of SARS-CoV-2 may be significantly better at evading vaccine-induced antibodies – but preliminary evidence suggests it is less likely to cause severe illness in the lungs.
Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…
Safety trials are underway for a Cambridge-led vaccine that could be used as a booster targeting Covid-19 virus variants and relatives that threaten future coronavirus pandemics.
In experiments using saliva samples from COVID-19 patients, the gum, which contains the ACE2 protein, neutralized the virus.
AI-designed Xenobots reveal an entirely new form of biological self-replication—promising for regenerative medicine.
Test could measure patient immunity against multiple COVID-19 variants such as Omicron and Delta at once and inform which synthetic monoclonal antibody to use for treatments.
The Corona pandemic has a major impact on all areas of life. Nearly everyone is affected in some way – in their health, in their jobs, in their entire lives. But there are also notable bright spots. Chief among these effects is the rapid development of vaccines, test kits and, in the future, medicines that are making a significant contribution to overcoming the crisis. Microfluidic components…
There has been a "positive shift" in inclusive gender practices in Covid-19 vaccine research, but there is still room for improvement, experts say. Women have been equally recruited and represented in randomised control trial research about Covid-19 vaccine safety, efficacy and effectiveness, according to a new study by The George Institute for Global Health and The Australian National…
French researchers have found that addressing concerns related to the Covid-19 vaccination via a chatbot interface might be capable of swaying the vaccine-hesitant. Vaccine hesitancy is one of the major challenges in containing the Covid-19 pandemic. Previous studies have revealed that mass communication—through short messages relayed by television or radio—is not a very effective means of…
Researchers from Cleveland Clinic have opened a novel study for a vaccine aimed at eventually preventing triple-negative breast cancer, the most aggressive and lethal form of the disease. This phase I trial is designed to determine the maximum tolerated dose of the vaccine in patients with early-stage triple-negative breast cancer and to characterize and optimize the body’s immune response. The…
“Twindemic” is a term that has not yet been in the headlines but is likely to become part of our lexicon as the summer progresses.
Scientists at Lausanne University Hospital (CHUV) and École polytechnique fédérale de Lausanne (EPFL) have discovered a highly potent monoclonal antibody that targets the SARS-CoV-2 spike protein and is effective at neutralizing all variants of concern identified to date, including the delta variant. Their findings are published in the journal Cell Reports.
The Covid-19 crisis that gripped England between September 2020 and June 2021 can be thought of as a series of overlapping epidemics, rather than a single event, say researchers at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and the German Cancer Research Center.
Hope for a future without fear of Covid-19 comes down to circulating antibodies and memory B cells. Unlike circulating antibodies, which peak soon after vaccination or infection only to fade a few months later, memory B cells can stick around to prevent severe disease for decades. And they evolve over time, learning to produce successively more potent “memory antibodies” that are better at…
After infection with SARS-CoV-2, where does the immune system store the memory to provide long-term protection against reinfection? Though numerous studies have examined blood to track immune responses to SARS-CoV-2, a new study of Covid survivors shows that the memory of the infection is primarily stored in T and B cells within the lung and the lymph nodes surrounding the lung.
Long COVID symptoms rarely persisted beyond 12 weeks in children and adolescents unlike adults.
Study suggests need for better ventilation and tight-fitting masks, in addition to widespread vaccination to help stop spread of the virus.
A two-minute passive-test that measures people’s brain waves in response to a series of images, 'Fastball EEG', could help expand early dementia diagnosis.
According to new research, vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death from 14 days post the second dose vaccination, when substantial immunity should be expected.
Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body’s own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.
Thousands of unvaccinated French health workers face suspension without pay under a new COVID-19 law that punishes people in care professions who refuse to get immunised against the virus.
Hospitalized Covid-19 patients are substantially more likely to harbor autoantibodies — antibodies directed at their own tissues or at substances their immune cells secrete into the blood — than people without Covid-19, according to a new study.
Covid-19 infection does not appear to affect the lung function of young adults, according to new research presented at the ‘virtual’ European Respiratory Society International Congress. In the first study to investigate the impact of Covid-19 infection on lung function, researchers led by Dr Ida Mogensen, a post-doctoral fellow at the Karolinska Institute, Stockholm, Sweden, found that even…
Researchers in Thailand have developed a device to get the most out of vaccine supplies: The automated vaccine filling machine from the Faculty of Engineering at Chulalongkorn University can fill AstraZeneca vaccine into syringes with precision, speed, and safety, helping to increase the number of vaccinated people by 20 percent. The prototype is now operating at Chula Vaccination Center and more…
Adults who have received a double vaccination are 49% less likely to have Long Covid should they contract a Covid-19 infection, according to new research from King's College London. The scientists analysed data from participants logging their symptoms, tests and vaccines on the UK ZOE COVID Symptom Study app between 8th December 2020 and 4 July 2021, including 1,240,009 (first dose) and 971,504…
Delegates at an international radiography conference were given an insight into the impact Covid-19 has had on their profession and practice in five countries across the world. A special session at the online ISRRT (International Society of Radiographers and Radiological Technologists) congress in Dublin (August 20-22) heard experiences from Thailand, Nigeria, Italy, India and Ireland, with…
The World Health Organization (WHO) has taken a closer look at coronavirus variant B.1.621. The strain, first encountered in January 2021 in Colombia, shows traits that could enable the virus to circumvent immune response to vaccination. As a result, the variant, named "Mu", has been classified as "Variant of Interest" (VOI). Despite its prominence in Colombian new infection,…
Researchers from the University of Oxford have announced the results of a study into thrombocytopenia (a condition with low platelet counts) and thromboembolic events (blood clots) following vaccination for Covid-19, some of the same events which have led to restricted use of the Oxford-AstraZeneca vaccine in a number of countries.
Scientists have grown beating heart cells to attempt to identify drugs to prevent Covid-19-related heart damage. Concerns over the extent of cardiac damage among Covid patients emerged during the coronavirus pandemic and there are also suggestions that the impact on cardiomyocytes could contribute to the symptoms of long Covid. To explore these issues, a research team at the University of…
Each wave of the pandemic has underscored just how contagious Covid-19 is, but there is less clarity among experts on exactly when—and to what extent—infected individuals are most likely to spread the virus.
Obtaining two vaccine doses remains the most effective way to ensure protection against the Covid-19 Delta variant of concern dominant in the UK today, according to a study from the University of Oxford. Conducted in partnership with the Office of National Statistics (ONS) and the Department for Health and Social Care (DHSC), the study found that with Delta, Pfizer-BioNTech and Oxford-AstraZeneca…
Will telehealth replace traditional in-person healthcare? Healthcare and digital health professionals around the world have moved beyond this question. Telehealth scenarios are here to stay, and so is traditional healthcare. The relevant question is how both can be combined for optimum results. This is the focus of hybrid care models. Jonah Comstock of HIMSS recently presented a webinar on…
New research from the University of Oxford and the UK Centre for Ecology & Hydrology uses mathematical modelling to determine the most equitable way to share vaccines between nations. Vaccines provide a route to achieving high levels of immunity against SARS-CoV-2 across populations, and provide a route to reopening economies, tourism, and livelihoods. However, vaccine resources amongst…
A new study of patients with cerebral venous thrombosis (CVT) following Covid-19 vaccination provides a clearer guide for clinicians trying to diagnose and treat patients. The research, led by University College London (UCL) and UCL Health and published in The Lancet, is the most detailed account of the characteristics of CVT, when it is caused by the novel condition vaccine-induced immune…
Some people change the narrative about technology and society. One of them is Nuria Oliver, Chief Data Scientist at Data-Pop Alliance, Chief Scientific Advisor at the Vodafone Institute, and Co-founder and Vice-president of the European Laboratory for Learning and Intelligent Systems (ELLIS). In an interview with HiE, she explains how she develops computational tools and uses artificial…
Nanocontainers can transport substances into cells where they can then take effect. This is the method used in, for example, the mRNA vaccines currently being employed against Covid-19 as well as certain cancer drugs. In research, similar transporters can also be used to deliver labelled substances into cells in order to study basic cellular functions. To take advantage of their full potential,…
Italy, France, and Greece have made Covid-19 vaccination mandatory for healthcare workers, and England is making it compulsory for care home workers and consulting on whether to extend this to healthcare workers and other social care staff. Experts debate in The BMJ whether frontline health and social care workers should be compelled to take up the vaccine, if efforts to encourage them fail.…
A novel study published in AACC’s The Journal of Applied Laboratory Medicine shows that delaying the second Covid-19 vaccine dose for more than the recommended 3-4 weeks results in higher antibody levels. This finding could play a vital role in shaping vaccine distribution strategies that increase access to the vaccine around the globe.
In view of the continuing high numbers of infections, vaccination offers important protection against severe Covid-19 disease. Scientists from the Faculty of Medicine – University of Freiburg have now been able to determine in detail at what time point initial immune protection is established after vaccination with an mRNA-based vaccine and how the reactions of the various components of the…
Scientists from the German Cancer Research Center and Heidelberg University Hospital have for the first time been able to delay the development of hereditary colorectal cancer with a protective vaccination. Mice with a hereditary predisposition to colorectal cancer survived significantly longer after vaccination than unvaccinated animals. Combining the vaccination with an anti-inflammatory drug…
Markers in our blood – ‘fingerprints’ of infection – could help identify individuals who have been infected by SARS-CoV-2, the coronavirus that causes Covid-19, several months after infection even if the individual had only mild symptoms or showed no symptoms at all, say Cambridge researchers. The team has received funding from the National Institute for Health Research to develop a test…
The Lausanne University Hospital (CHUV) and EPFL teamed up to develop a new test that’s sensitive enough to measure the amount of SARS-CoV-2 neutralizing antibodies present in the bloodstream. The scientists’ discovery, published in Science Translational Medicine, opens promising new avenues for tracking immunity acquired by infection or vaccination.
To date, there are no effective antidotes against most virus infections. An interdisciplinary research team at the Technical University of Munich (TUM) has now developed a new approach: they engulf and neutralize viruses with nano-capsules tailored from genetic material using the DNA origami method. The strategy has already been tested against hepatitis and adeno-associated viruses in cell…
The net benefit of vaccinating children is unclear, and vulnerable people worldwide should be prioritised instead, say experts in The BMJ today. But others argue that Covid-19 vaccines have been approved for some children and that children should not be disadvantaged because of policy choices that impede global vaccination.
Rapid tests effectively broke Covid-19 infection chains in spring 2021. This is shown by a model developed by researchers of the ECONtribute: Markets & Public Policy Cluster of Excellence of the Universities of Bonn and Cologne, the Collaborative Research Center Transregio 224 EPoS of the Universities of Bonn and Mannheim, and the Institute for the Study of Labor (IZA). According to the…
234 random passersby got the opportunity to try a new virtual reality game, when researchers from the University of Copenhagen visited Fælledparken to test the efficiency of VR technology within health information. During the event, the participants tried their strength against a new VR game that simulates the effect of herd immunity. The game is developed by researchers at the Virtual Learning…
A new paper on long-Covid describes persistent symptoms six months after acute Covid-19, even in young home isolated people. The study from the Bergen Covid-19 Research Group, which was published in the journal Nature Medicine, followed infected patients during the first pandemic wave in Bergen. "The main novel finding is that more than fifty per cent of young adults up to 30 years old,…
In-vitro-diagnostics company bioMérieux has launched Episeq SARS-CoV-2, a genomic software solution to support microbiology labs in identification and reporting from raw sequencing data related to SARS-CoV-2 variants. Viral mutation is a naturally occurring phenomenon leading to the emergence of variants that can have different characteristics. Today, a number of SARS-CoV-2 variants are…
La Trobe University researchers are the first in the world to characterize precisely how Covid-19 attacks lung tissues — an important step in preventing long-term damage.
Higher levels of vaccination against COVID-19 were associated with lower rates of infection with SARS-CoV-2 among a group of unvaccinated people of 16 years of age and under.
A team of Johns Hopkins researchers has developed a rapid blood test that could confirm a person has been vaccinated while they wait to board a plane or enter a sporting event.
Mining the world's most comprehensive drug repurposing collection for Covid-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.
Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.
A study of healthcare workers shows they were three times more likely to become infected during the Covid-19 pandemic compared to the general population. Around one in five of workers who were infected were asymptomatic and unaware they had Covid-19. The study published in ERJ Open Research also shows that it was not only frontline staff who faced the higher risk, suggesting that there was…
Almost 1 million extra deaths relating to the Covid-19 pandemic occurred in 29 high income countries in 2020, finds a study published by The BMJ. Except for Norway, Denmark and New Zealand, all other countries examined had more deaths than expected in 2020, particularly in men. The five countries with the highest absolute number of excess deaths were the US, UK, Italy, Spain, and Poland.
A low-cost, rapid diagnostic test for Covid-19 developed by Penn Medicine provides Covid-19 results within four minutes with 90 percent accuracy. A paper published this week in Matter details the fast and inexpensive diagnostic test, called RAPID 1.0 (Real-time Accurate Portable Impedimetric Detection prototype 1.0). Compared to existing methods for Covid-19 detection, RAPID is inexpensive and…
Delaying the second dose of Covid-19 vaccines, at least for people aged under 65, could result in up to 20% lower mortality, but only under certain conditions, finds a US study published by The BMJ. These conditions include a one dose vaccine effectiveness (efficacy) of 80% or higher and vaccination rates of 0.1% to 0.3% of the population per day. If these conditions apply, the researchers say…
A large study from Denmark and Norway published by The BMJ sheds more light on the risk of rare blood clots in adults receiving their first dose of the Oxford-AstraZeneca Covid-19 vaccine. The findings show slightly increased rates of vein blood clots including clots in the veins of the brain, compared with expected rates in the general population. However, the researchers stress that the risk of…
Women and men are different – nobody would argue with this statement. However, in medicine, gender plays a subordinate role. Neither research, prevention nor therapy adequately reflect this difference. “This is no longer acceptable,” says internist and cardiologist Prof. Dr. Vera Regitz-Zagrosek.
Clinical diagnostics company Beckman Coulter announced the European launch of the DxA 5000 Fit, a workflow-automation solution designed to fit into medium-sized labs that run fewer than 5,000 tests a day. The clinical laboratory has gone through trial by fire in 2020, where total testing was 245% of baseline volumes, with ~55% being SARS-CoV-2 molecular tests. Despite vaccines, many industry…
A collaboration spanning four research labs and hundreds of miles has used the organ-on-a-chip (Organ Chip) technology from the Wyss institute at Harvard Univesity to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes Covid-19. The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the…
Researchers from Cleveland Clinic and Case Western Reserve University collaborate on genetic study of SARS-CoV-2 mutations. Results show how the different COVID-19 clades evolved.
Advice on the application of the Medicrime Convention in the context of counterfeit COVID-19 vaccines.
A team led by a clinical academic at University College London (UCL) has outlined the mechanism behind rare cases of blood clots and low platelets seen in patients who have had the Oxford/AstraZeneca vaccine. The new study, published in the New England Journal of Medicine, highlights the importance of rapidly spotting this new syndrome, known as vaccine-induced thrombosis and thrombocytopenia…
The world is still failing to develop desperately needed antibacterial treatments, despite growing awareness of the urgent threat of antibiotic resistance, according to a new report by the World Health Organization. WHO reveals that none of the 43 antibiotics that are currently in clinical development sufficiently address the problem of drug resistance in the world’s most dangerous bacteria.…
New research by University of Texas at Dallas scientists could help solve a major challenge in the deployment of certain Covid-19 vaccines worldwide — the need for the vaccines to be kept at below-freezing temperatures during transport and storage. In a study published online in Nature Communications, the researchers demonstrate a new, inexpensive technique that generates crystalline…
Researchers at the University of Oxford report that the risk of the rare blood clotting known as cerebral venous thrombosis (CVT) following Covid-19 infection is around 100 times greater than normal, several times higher than it is post-vaccination or following influenza. The study authors, led by Professor Paul Harrison and Dr Maxime Taquet from Oxford University’s Department of Psychiatry and…
Any future attempts to reduce the spread of Covid-19 should be focused on tackling close airborne transmission of the virus which is considered to be the primary route for its circulation, according to experts. Respiratory experts argue that it is now clear that SARS-CoV-2 is most likely to transmit between people at close range through inhalation rather than through contact with surfaces or…
Researchers running the Com-Cov study, launched in February to investigate alternating doses of the Oxford-AstraZeneca vaccine and the Pfizer vaccine, announce that the programme will be extended to include the Moderna and Novavax vaccines in a new study.
SARS-CoV-2 is the virus responsible for the Covid-19 pandemic. We know that mutations in the genome of SARS-CoV-2 have occurred and spread, but what effect do those mutations have? Current methods for studying mutations in the SARS-CoV-2 genome are very complicated and time-consuming because coronaviruses have large genomes, but now a team from Osaka University and Hokkaido University have…
Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms’ DNA. While the system could potentially be useful in treating a variety of diseases, CRISPR-Cas9 editing involves cutting DNA strands, leading to permanent changes to the cell’s genetic material. Now, in a paper published online in Cell,…
Clinicians using a new viral screening test can not only diagnose Covid-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses—like influenza—that might be mistaken for the coronavirus. At the same time, they can sequence the virus, providing valuable information on the spread of Covid-19 mutations and variants. The new test, dubbed…
A new study by scientists at Kyoto University and the University of Fukui may offer hope for adults who have lost their teeth. The team reports that an antibody for one gene - uterine sensitization associated gene-1 or USAG-1 - can stimulate tooth growth in mice suffering from tooth agenesis, a congenital condition. The paper was published in Science Advances. Although the normal adult mouth has…
A University of Manchester team has applied new techniques to detect and track the transmission of Covid-19 in hospital. The proof of concept system combines the movement and interaction of staff and patients with genomic sequencing of the virus, helping to signpost how best to improve patient pathways, staff movement and reduce risk. They identified hotspots within hospitals where patients and…
Experts from Sweden, Finland and Kenya are using digital microscopy combined with Artificial Intelligence (AI) to deliver a rapid and effective cervical screening service to rural locations in Kenya. The project sees AI and digital diagnostics bridge the gap between low-resource settings and the availability of centralised AI-enhanced expertise and pathology services, located in larger cities in…
Tumor vaccines can help the body fight cancer. Mutations in the tumor genome often lead to protein changes that are typical of cancer. A vaccine can alert the patients' immune system to these mutated proteins. For the first time, physicians and cancer researchers from Heidelberg and Mannheim have now carried out a clinical trial to test a mutation-specific vaccine against malignant brain tumors.…
In the largest study of its kind to date, researchers at Massachusetts General Hospital, Brigham and Women’s Hospital and the Ragon Institute of MGH, MIT and Harvard have found the new mRNA Covid-19 vaccines to be highly effective in producing antibodies against the SARS-CoV-2 virus in pregnant and lactating women. They also demonstrated the vaccines confer protective immunity to newborns…
More than four in five (86%) people who were unsure or said no to a Covid-19 vaccine in December 2020 would now take one, or have already been vaccinated, finds the latest research by the Virus Watch study conducted by University College London (UCL).
Scientists from Singapore found that antibodies against SARS-CoV-2 wane at different rates, lasting for mere days in some individuals, while remaining present in others for decades. The study, published in The Lancet Microbe, shows that the severity of the infection could be a deciding factor in having longer-lasting antibodies. Individuals with low levels of neutralising antibodies may still be…
Researchers are developing a COVID-19 vaccine that could provide protection against both existing and future strains of the COVID-19 virus, and other coronaviruses, and cost about $1 a dose has shown promising results in early animal testing.
Researchers at University of Toronto have developed a new test to accurately detect coronavirus antibodies in a drop of blood in less than an hour.
Researchers investigated whether the vaccine recipients developing unusual thrombotic events and thrombocytopenia could have a prothrombotic disorder caused by platelet-activating antibodies directed against a platelet protein, as a similar mechanism is known to be caused by heparin and sometimes other environmental triggers.
Even as vaccines are becoming more readily available, protecting against the asymptomatic and pre-symptomatic spread of the virus (SARS-CoV-2) that causes Covid-19 is key to ending the pandemic, say two infectious disease experts at the Georgetown University Medical Center. In their Perspective, “SARS-CoV-2 Transmission Without Symptoms,” published in the journal Science, they make the case…
Moderna and IBM announced their intentions to explore technologies, including artificial intelligence, blockchain and hybrid cloud, that could help support smarter Covid-19 vaccine management. Central to the effort will be a pilot of open, standardized, technology-enabled vaccine distribution approaches aimed to improve supply chain visibility and foster near real-time tracking of vaccine…
In what is believed to be the first published study of Covid-19 vaccine effectiveness in long-term care facilities such as nursing homes, a research team co-led by the Yale School of Public Health found a widely used vaccine is highly successful in preventing infections. Residents of such facilities, particularly those in skilled nursing facilities (SNFs), have experienced disproportionately high…
The highly infectious variant of Covid-19 discovered in Kent, which swept across the UK last year before spreading worldwide, is between 30 and 100 per cent more deadly than previous strains, new analysis has shown. A pivotal study, by epidemiologists from the Universities of Exeter and Bristol, has shown that the SARS-CoV-2 variant, B.1.1.7, is associated with a significantly higher mortality…
Diphtheria – a relatively easily-preventable infection – is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India. The researchers, led by scientists at the University of Cambridge, say that the impact of Covid-19 on diphtheria vaccination schedules, coupled with a rise in…
An international research group led by the University of Basel has developed a promising strategy for therapeutic cancer vaccines. Using two different viruses as vehicles, they administered specific tumor components in experiments on mice with cancer in order to stimulate their immune system to attack the tumor. The approach is now being tested in clinical studies.
Temperature control equipment and systems company Lauda is expanding its portfolio with its new Versafreeze product line. This consists of high-quality ultra-freezers which have been optimized for the extreme requirements of deep-freeze storage. Lauda thereby meets the requirements of vaccine producers, pharmaceutical service providers, vaccination centers and universities for the safe storage of…
The European Commission has launched a contingency plan to meet the challenge of the various mutations of the coronavirus. Karolinska Institutet and Karolinska University Hospital are contributing to a new network for the evaluation and testing of new vaccines. The network is called "Vaccelerate" and it will contribute both to the evaluation of ongoing and future vaccinations, as well…
The European Commission has proposed a European Partnership for Health Innovation under Horizon Europe - an endeavour that is supported by health industry stakeholders representing pharmaceutical and medical technology companies. In a joint statement, COCIR, EFPIA, EuropaBio, MedTech Europe and Vaccines Europe voice their approval: The Covid-19 pandemic has shown the importance of an environment…
A potential new treatment to protect immunosuppressed patients from human cytomegalovirus (HCMV) has been discovered by scientists at the University of Cambridge. Their study shows that certain epigenetic inhibitors expose and help to destroy dormant HCMV infections, which often reactivate to cause serious illness and death in these vulnerable groups. Subject to clinical trials, their proposed…
For many women, swollen lymph nodes are a red flag pointing to breast cancer – but may also be a normal immune reaction to a Covid-19 vaccination. In this Q&A, breast imaging experts address the most important facts on the topic.
Covid-19 vaccine passports could be created, but significant challenges need to be overcome first, according to a report from a panel led by Oxford Professors Melinda Mills and Chris Dye, which outlines a dozen issues which must be addressed before passports can be introduced. The report is published by the SET-C (Science in Emergencies Tasking: Covid-19) group at the Royal Society and it…
Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. In the latest predictions for cancer deaths in the EU and UK for 2021, published in the cancer journal Annals of Oncology, researchers led by Carlo La Vecchia (MD), a professor…
Preventing air contamination in healthcare facilities is crucial to minimise the airborne spread of Covid-19 and its new strains. Universal masking, rigorous use of and safe disposal of PPE, plus building ventilation are vital. Twenty-four studies reporting hospital SARS-CoV-2 air contamination are summarised in a meta-analysis by a multi-institutional team of French researchers. These show that,…
The impact of Covid-19 in Africa has been vastly underestimated, warn researchers in a new study. Outside of South Africa, this is the first study to provide systematic surveillance data capturing the impact of Covid-19 in Africa. Their findings are based on polymerase chain reaction (PCR) test results for 364 deceased people of all ages at the University Teaching Hospital morgue in Lusaka,…
The PCR test is the most accurate tool to identify SARS-CoV-2. However, valid results are often available only after days. Moreover, the laboratory must be well equipped, have trained personnel and sufficient financial resources. All of this is usually a problem in Africa. A portable suitcase could help. In cooperation with several African universities, scientists at Leipzig University have found…
Scientific and public health experts have been raising the alarm for decades, imploring public officials to prepare for the inevitability of a viral pandemic. Infectious epidemics seemingly as benign as "the flu" and as deadly as the Ebola virus provided ample warning, yet government officials seemed caught off guard and ill prepared for dealing with Covid-19.
People who are sceptical of getting vaccinated against infectious diseases may soon get a whole new perspective on things. Professor Robert Böhm and Associate Professor Guido Makransky from the Center for Social Data Science (SODAS) and the Department of Psychology at the University of Copenhagen have received DKK three million in funding from EIT Health for developing a virtual reality app to…
Researchers from the University of Nottingham have discovered a novel antiviral property of a drug that could have major implications in how future epidemics/pandemics – including Covid-19 – are managed. The study, published in Viruses, shows that thapsigargin is a promising broad‑spectrum antiviral, highly effective against SARS-CoV-2, a common cold coronavirus, respiratory syncytial virus…
USC researchers have developed a new method to counter emergent mutations of the coronavirus and hasten vaccine development to stop the pathogen responsible for killing thousands of people and ruining the economy.
The continuing corona virus epidemic has impacted strongly on cancer care and research, including the delay of treatments and diagnoses as well as on trials of new therapies, and the shift in research to develop a Covid-19 vaccine. However, the session ‘Cancer research and Covid-19’, during the National Cancer Research Institute (NCRI) Virtual Showcase (online 2-3 November) looked at how UK…
The emergence of SARS-CoV-2 virus variants that are adding twists in the battle against COVID-19 highlight the need for better genomic monitoring of the virus, says Katia Koelle, associate professor of biology at Emory University.
This FAQ from the American College of Allergy, Asthma and Immunology is provided to help answer patient questions about COVID-19 vaccines. These recommendations are based on best knowledge to date, but could change at any time, pending new information and further guidance from the FDA or CDC.
Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.
The Belgian initiative icovid, which supports radiologists in the assessment of CT images of the lungs of COVID-19 patients, has grown into a multicentre European project, co-funded by the EU Horizon 2020 programme. Icovid was set up in March by UZ Brussel, KU Leuven, icometrix and ETRO, an imec research group of VUB.
As the first coronavirus vaccines started to be rolled out at the end of a tumultuous 2020, UK officials unexpectedly endorsed stretching the gap between the first and second vaccine dose by up to three months – an approach also considered by other countries.
Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too. Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and…
Clinical diagnostics company Beckman Coulter launched its Access SARS-CoV-2 IgG II assay in countries accepting the CE Mark. The new Access SARS-CoV-2 IgG II assay quantitatively measures a patient’s level of antibodies in response to a previous SARS-CoV-2 infection. The ability to establish a quantitative baseline to evaluate an individual’s immune response to the SARS-CoV-2 virus allows…
The corona pandemic, which has been rampant for a year, and the Ebola epidemic of 2017 have shown the value of online courses for the rapid worldwide dissemination of life-saving knowledge, the German Hasso Plattner Institute (HPI) points out. One year ago, the World Health Organization (WHO) published its first online course on Covid-19 diseases. HPI head Prof. Christoph Meinel reflects on its…
With Covid-19 dominating medical science and human concern, chemists at the University of Sydney have developed a method to quickly and safely synthesise protein vaccines for respiratory diseases for pre-clinical tests. Their approach can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes Covid-19.
Scientists at The Ohio State University have discovered a new variant of SARS-Cov-2, the virus that causes Covid-19. The new variant carries a mutation identical to the U.K. strain, but it likely arose in a virus strain already present in the United States. The College of Medicine researchers also report the evolution of another U.S. strain that acquired three other gene mutations not previously…
Researchers at Karolinska Institutet have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells. The research study, published in Science, shows that a combined nanobody had a particularly good effect – even if the virus mutated. According to the researchers, the…
Siemens Healthineers announced CE mark has been achieved to use anterior nose swab sampling for the Clinitest Rapid Covid-19 Antigen test. This sampling method can be less cumbersome and time consuming for both the provider and the patient. The test is a point-of-care cassette test that does not require laboratory instruments or specialized lab personnel to administer, and it delivers results in…
Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body’s immune system within the first few days of the illness. But in a study published in Nature, investigators at Northwestern Medicine show Covid-19 pneumonia is…
Even those who understand the scientific process, trust medical experts and know how important vaccines are for fighting infectious diseases might still have some questions or concerns about the new Covid-19 vaccines. Here, Thaddeus Stappenbeck, MD, PhD, helps set the record straight on 8 common questions, concerns and myths that have emerged about Covid-19 vaccines.
Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza. But, within days of closing their campus lab space as part of Covid-19 precautions, they turned their attention to a vaccine for SARS-CoV-2, the virus that causes Covid-19. Although the coronavirus was outside the lab’s specific area of expertise,…
Patients with acute heart failure nearly double their risk of dying if they get Covid-19, according to new research. The small, single centre study highlights the need for patients with heart failure to take extra precautions to avoid catching Covid-19. “Our results support prioritising heart failure patients for Covid-19 vaccination once it is available,” said study lead investigator Dr.…
ZTA Biotech, a Budapest-based biotech startup, has developed a Covid-19 antibody (IgG) test using the ELISA protocol. This new detection method represents a great step forward in determining if patients have had a coronavirus infection and if they might still have immunity to the disease. Early results have proven 100% in specificity after testing 280 samples, and 100% sensitivity by testing 260…
Hundreds of thousands of cervical cancer cases per year could be prevented through widespread vaccinations for human papillomavirus (HPV) and annual pap smear tests, says an expert at a top American hospital, Cleveland Clinic, marking Cervical Cancer Awareness Month in January. Dr. Robert DeBernardo, Section Head of Gynecologic Oncology and Vice Chair Subspecialty Care for Women’s Health at…
The Covid-19 vaccine developed by Oxford University/AstraZeneca has been given regulatory approval by the Medicines and Healthcare products Regulatory Agency (MHRA) after meeting required safety, quality and effectiveness standards. Following a rigorous, detailed scientific review by the MHRA’s expert scientists and clinicians and on the basis of the advice of its scientific, independent…
The Covid-19 pandemic came as a shock but not a surprise. Bodies around the world have been warning for years of a novel disease that could wipe out millions and crash the global economy. In February 2019, Dr Jonathan Quick, chair of the Global Health Council, told Raconteur: “Our greatest fear is being blindsided by a new virus, most likely due to animal-human spill over, which then readily…
Nearly twice as many people were admitted to hospital for Covid-19 at the height of the pandemic than were for influenza at the peak of the 2018/2019 flu season, a study of French national data published in The Lancet Respiratory Medicine journal has found (Covid-19, 89,530 patients vs influenza, 45,819 patients).
Nearly a quarter of the world’s population may not have access to a covid-19 vaccine until at least 2022, warns a study published by The BMJ. A second study estimates that 3.7 billion adults worldwide are willing to have a covid-19 vaccine, highlighting the importance of designing fair and equitable strategies to ensure that supply can meet demand, especially in low and middle income countries.
In a preclinical study, NIH scientists found that the commonly used antibiotic methacycline may be effective at combating the neurological problems caused by Zika virus infections.
None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, researchers conclude after the analysis of virus genomes from over 46,000 people with COVID-19 from 99 countries.
A senior UK health figure has highlighted how contrasting leadership approaches are impacting the response to the global coronavirus crisis. Dr Clare Gerada also fears that response is affecting health professionals and leaders within the sector, with a significant rise numbers seeking help for mental health issues. Delivering the prestigious Sir Godfrey Hounsfield Lecture to the 2020 British…
In the COVID-19 pandemic, 57 million people have already been infected worldwide. In the search for vaccines and therapies, a precise understanding of the virus, its mutations and transmission mechanisms is crucial.
In a new study, researchers performed a detailed imaging analysis to determine how the virus reprograms infected cells.
Germany’s lack of diagnostic ability led to significantly underestimation of its own as well as global Covid-19 infection levels during the first wave. Now, however, improved testing and diagnosis of the condition more realistically reveal nearer 20,000 new cases a day across the country, according to Professor Hendrik Streeck, one of the country’s leading virologists. Speaking at a virtual…
Re-starting the global economy for billions of people will depend on successfully overcoming logistical challenges in the ‘last mile’ of a COVID-19 vaccine’s journey to immunisation stations, according to a new report.
Scientists report on their detailed look at B cells' presence inside tumors. B cells represent the other major arm of the adaptive immune system, besides T cells, and could offer opportunities for new treatments against some kinds of cancers.
A new study suggests that individuals who have previously had COVID-19 are highly unlikely to contract the illness again, for at least six months following their first infection. The study, done as part of a major collaboration between the University of Oxford and Oxford University Hospitals (OUH) NHS Foundation Trust, was published as a pre-print.
For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.
Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.
Siemens Healthineers announced its SARS-CoV-2 IgG Antibody Test (sCOVG) has proven to measure neutralizing antibodies and has achieved CE Mark. The test is an enhanced version of the assay which became available globally this summer. It demonstrates the ability to detect neutralizing antibodies and reports quantitative results measuring the amount of neutralizing antibodies present in a patient's…
In early 1990, at Analytica, in Munich, a young US-American researcher Kary B Mullis received the award for biochemical analytics for his 1983 invention: the polymerase chain reaction (PCR) – a success topped in 1993 by the Nobel Prize for chemistry. Mullis’ work revolutionised DNA copying, a process which, before PCR, had taken weeks. Whilst initially PCR was used to create digital…
Measures to reduce the spread of Covid-19 through non-pharmaceutical interventions (NPIs) such as mask wearing and social distancing are a key tool in combatting the impact of the ongoing coronavirus pandemic. These actions also have greatly reduced incidence of many other diseases, including influenza and respiratory syncytial virus (RSV).
Researchers at Duke University and the University of California, Los Angeles, have developed a biomaterial that significantly reduces scar formation after wounding, leading to more effective skin healing. This new material, which quickly degrades once the wound has closed, demonstrates that activating an adaptive immune response can trigger regenerative wound healing, leaving behind stronger and…
An innovative nanoparticle vaccine candidate for the pandemic coronavirus produces virus-neutralizing antibodies in mice at levels ten-times greater than is seen in people who have recovered from COVID-19 infections. Designed by scientists at the University of Washington School of Medicine in Seattle, the vaccine candidate has been transferred to two companies for clinical development.
Merck announced a collaboration with Mammoth Biosciences Inc. for the development, scale-up and commercial production of Mammoth’s CRISPR-based SARS CoV-2 diagnostic test.
Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe. Speaking before he delivered the prestigious Michel Clavel lecture to the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which was due to take place…
Vaccines are being hailed as the solution to the COVID-19 pandemic, but the vaccine trials currently underway are not designed to tell us if they will save lives, reports Peter Doshi, Associate Editor at The BMJ. Several COVID-19 vaccine trials are now in their most advanced (phase 3) stage, but what will it mean exactly when a vaccine is declared “effective”? Many may assume that successful…
A new risk tool, developed by UK researchers to predict a person’s risk of being admitted to hospital and dying from COVID-19 has been published by The BMJ. With cases increasing in the UK and elsewhere, and winter approaching, there is an urgent need for reliable models that predict the likely course of COVID-19, to support decisions about shielding, hospital admission, treatment, and…
The present Coronavirus pandemic with all its effects on society – both health and economic – highlights the urgency of developing new therapies for COVID-19 treatment. At the same time, it demonstrates the necessity to become well prepared for new virus infections we may be facing in the future. To help control the current pandemic and brace for novel pathogens that may cause future…
As President Trump claims that he is immune to COVID-19 and isolated reports emerge of reinfection, what is the truth about immunity to COVID-19? To date, there have been six published cases of COVID-19 reinfection, with various other unverified accounts from around the world. Although this is a comparably small fraction of the millions of people known to have been infected, should we be…
Researchers at CSIRO, Australia's national science agency, have found that SARS-CoV-2, the virus responsible for COVID-19, can survive for up to 28 days on common surfaces including banknotes, glass – such as that found on mobile phone screens - and stainless steel.
An up-and-coming gene therapy for blood disorders. A new class of medications for cystic fibrosis. Increased access to telemedicine. These are some of the innovations that will enhance healing and change healthcare in the coming year, according to a distinguished panel of clinicians and researchers from Cleveland Clinic. In conjunction with the 2020 Medical Innovation Summit, Cleveland Clinic…