News • New antibodies discovered
Researchers snake toward a universal antivenom
Scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia.
Search for: "HIV" - 215 articles found
News • Invasive fungal infection
Cryptococcosis: Guideline for better diagnosis and treatment
A new guideline for the diagnosis and treatment of cryptococcosis is designed to support medical staff in handling invasive fungal infections and provide guidance and support in decision-making.
News • Sexual health pilot project
Vending machines offer convenient STI testing
Vending machines dispensing self-test kits for sexually transmitted infections (STIs) have proven to be an effective and widely accepted means of reaching individuals who rarely or never get tested.
Sponsored • Effects of the pandemic on patient care
Why safe blood collection is more important to nurses in 2023 than ever before
Being able to rely on a quality, safety-engineered device for blood collection allows staff to perform their tasks with the minimum of fuss. Nurse Constance Mak talks about the benefits of closed collection systems.
News • HIV & hepatitis detection
HIV, hepatitis B and hepatitis C can be detected from a single drop of blood, study shows
Data on a test that can detect HIV, hepatitis B and hepatitis C from a single drop of blood is being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases.
News • New treatment insights
Successful cure of HIV infection after stem cell transplantation
A new study confirms that haematopoietic stem cell transplantation can be used to cure patients with HIV infections. This third successful case gives new insights into the underlying processes.
News • Appeal for sustainability
POCT: Why the medical sector must tackle its single-use diagnostic waste
During the Covid-19 pandemic, the use of these single-use diagnostics, or point-of-care tests has exploded. This is having major environmental consequences, experts point out.
News • CSCC study finds distinct subgroups
Cervical cancer: major new clue to understanding aggressiveness
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
Article • Infection prevention
Vaccination: why ‘positive consensus’ is crucial
Vaccination projects across the world are at a pivotal post-Covid moment, according to one of the leading experts in the field. Speaking to Healthcare in Europe ahead of the World Innovation Summit for Health (WISH) congress in Qatar – where vaccination will be a central topic – Dr Jerome Kim said there is an urgent need to regain a ‘positive consensus’ around the value of vaccines. He…
News • Insufficient treatment advice
Monkeypox: experts state urgent need for high quality guidelines
A lack of high quality, up to date clinical guidance on monkeypox may be hampering effective and safe treatment of the infection around the world, a new review finds.
News • Genome instability
Gene editing via CRISPR/Cas9 can lead to cell toxicity
Researchers identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches.
News • To enter human cells
SARS-CoV-2 hijacks antiviral human proteins
SARS-CoV-2 depends on the broadly antiviral interferon-induced human transmembrane proteins , to enter human cells and replicate inside them.
News • Elusive variants
Rare genetic markers of drug-resistant tuberculosis identified
The search for rare mutations in bacterial genome could lead to better diagnostics and treatments – reducing morbidity caused by the deadly disease.
News • Coronavirus complications
Covid-19 infection linked to higher risk of neuropathy
Researchers have found another long-term complication associated with Covid-19 infections: peripheral neuropathy during and following their bouts with the virus.
News • AI-GUIDE system
Handheld robot can help stem fatal blood loss
The AI-Guided Ultrasound Intervention Device is a lifesaving technology that helps a range of users deliver complex medical interventions at the point of injury.
Article • Point-of-care testing
Emerging technologies in POCT
Considerable advances in point-of-care testing (POCT) devices are emerging from lab-on-a-chip platforms, innovations in smartphone-based technology and wearable technology. Cloud-based deep learning systems herald a future revolution.
News • Roadmap for Improvement
Inaugural Global Women’s Health Index
Hologic, Inc. shared the findings from its inaugural Hologic Global Women’s Health Index, the world’s most comprehensive, globally comparative survey about women’s health.
News • Genome editing
Using CRISPR to speed up Covid-19 testing
A research team led by scientists in the labs of Jennifer Doudna, David Savage and Patrick Hsu at the University of California, Berkeley, is aiming to develop a rapid Covid-19 diagnostic test that is much faster and easier to deploy than qRT-PCR. It has now combined two different types of CRISPR enzymes to create an assay that can detect small amounts of viral RNA in less than an hour. Doudna…
News • Deep learning vs Aids
AI app could help diagnose HIV more accurately
Pioneering technology developed by University College London (UCL) and Africa Health Research Institute (AHRI) researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries. Academics from the London Centre for Nanotechnology at UCL and AHRI used deep learning (artificial intelligence/AI) algorithms to improve health workers’…
News • Cardiology research
Statins could reduce risk of cancer among heart failure patients
Statin use among patients with heart failure is associated with a 16% lower risk of developing cancer compared with non-statin users during an average of four years of follow-up. This is according to new research published in the European Heart Journal. In addition, the study found that statin use was associated with a 26% reduced risk of dying from cancer over the same period.
News • Fighting the pandemic
90 drugs against Covid-19
Mining the world's most comprehensive drug repurposing collection for Covid-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.
News • Molecular research
How retroviruses become infectious
Understanding every step in the life cycle of a virus is crucial for identifying potential targets for treatment. Now, scientists at the Institute of Science and Technology (IST) Austria were able to show how a virus from the retrovirus family – the same family as HIV – protects its genetic information and becomes infectious. Furthermore, they show an unexpected flexibility of the virus. This…
Article • Digital pathology
AI delivers cervical cancer screening to rural areas of Kenya
Experts from Sweden, Finland and Kenya are using digital microscopy combined with Artificial Intelligence (AI) to deliver a rapid and effective cervical screening service to rural locations in Kenya. The project sees AI and digital diagnostics bridge the gap between low-resource settings and the availability of centralised AI-enhanced expertise and pathology services, located in larger cities in…
Sponsored • Wako β-glucan test
Better detection and diagnosis of fungal infections
Beta-glucan tests are proving to be pivotal in the better detection and diagnosis of fungal infections. As a robust complimentary test for traditional testing techniques and biomarkers, it is helping clinicians deliver rapid results and offering greater reassurance in more accurately identifying such infections. β-glucan testing, which is an in vitro diagnostic test, is regularly used at…
News • nsp14-ExoN
Is this the Achilles' heel of the coronavirus?
Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.
News • "Faces" of the disease
Covid-19: researchers identify at least 5 variants
According to current studies, the Covid-19 disease which is caused by the SARS-CoV-2 coronavirus comprises at least five different variants. These differ in how the immune system responds to the infection. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, together with other experts from Germany, Greece and the Netherlands, present these findings…
News • Virion recreated
First computational model of entire SARS-CoV-2 virus
Researchers at the University of Chicago have created the first usable computational model of the entire virus responsible for Covid-19—and they are making this model widely available to help advance research during the pandemic. “If you can understand how a virus works, that’s the first step towards stopping it,” said Prof. Gregory Voth, whose team created the model published in…
News • Promising candidate
Single-dose nanoparticle vaccine for Covid-19 in development
Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza. But, within days of closing their campus lab space as part of Covid-19 precautions, they turned their attention to a vaccine for SARS-CoV-2, the virus that causes Covid-19. Although the coronavirus was outside the lab’s specific area of expertise,…
News • Austrian study
Insights into transmission of SARS-CoV-2
In the COVID-19 pandemic, 57 million people have already been infected worldwide. In the search for vaccines and therapies, a precise understanding of the virus, its mutations and transmission mechanisms is crucial.
Article • Diagnosing SARS-CoV-2
The arsenal: Molecular (PCR), antigen and antibody testing
Germany’s lack of diagnostic ability led to significantly underestimation of its own as well as global Covid-19 infection levels during the first wave. Now, however, improved testing and diagnosis of the condition more realistically reveal nearer 20,000 new cases a day across the country, according to Professor Hendrik Streeck, one of the country’s leading virologists. Speaking at a virtual…
News • Intratumoral B cells
Another side to cancer immunotherapy?
Scientists report on their detailed look at B cells' presence inside tumors. B cells represent the other major arm of the adaptive immune system, besides T cells, and could offer opportunities for new treatments against some kinds of cancers.
Article • Workplace inclusion
Surgery in a wheelchair: breaking barriers in the OR and beyond
You don’t need to stand up to stand out. A few decades ago, a little boy believed he could tend to patients in spite of being in a wheelchair – and he did. During the EANS 2020 virtual meeting, Prof. Dr. Thomas Kapapa explained how he breaks barriers and helps promote diversity every day in his clinical practice in Germany and Malawi.
News • Block of erythrocytes formation
SARS-CoV-2 might attack red marrow
Specialists from the Department of Fundamental Medicine of Far Eastern Federal University (FEFU) with Russian and Japanese colleagues have probed into mechanisms of COVID-19 inside-the-body distribution linked to erythrocytes damaging.
Sponsored • Product of the Month
Needlestick Injuries are history
Injuries due to contaminated puncture devices are still the most frequent cause of accidents in hospitals. This is a significant source of danger for many employees in the healthcare industry. At this moment in time, there are already more than 20 bloodborne pathogens that we know of. The most dangerous are HBV, HCV and HIV. Recent studies show that it is up to ten times more likely for more…
News • COVID immunity research
Coronavirus re-infection: what we know so far – and the vital missing clues
As President Trump claims that he is immune to COVID-19 and isolated reports emerge of reinfection, what is the truth about immunity to COVID-19? To date, there have been six published cases of COVID-19 reinfection, with various other unverified accounts from around the world. Although this is a comparably small fraction of the millions of people known to have been infected, should we be…
News • Uncommon, but reversible
Sudden deaf: permanent hearing loss linked to COVID-19
Although uncommon, sudden permanent hearing loss seems to be linked to COVID-19 infection in some people, warn doctors, reporting the first UK case in the journal BMJ Case Reports. Awareness of this possible side effect is important, because a prompt course of steroid treatment can reverse this disabling condition, they emphasise. Sudden hearing loss is frequently seen by ear, nose and throat…
News • 3-D analysis
RNA molecules in high resolution
University of Maryland scientists have developed a method to determine the structures of large RNA molecules at high resolution.
Video • For breakthroughs against Hepatitis C
Nobel Prize in Medicine goes to Harvey J. Alter, Michael Houghton and Charles M. Rice
The 2020 Nobel Prize in Medicine is awarded to three scientists who have made a decisive contribution to the fight against blood-borne hepatitis, a major global health problem that causes cirrhosis and liver cancer in people around the world. Harvey J. Alter, Michael Houghton and Charles M. Rice made seminal discoveries that led to the identification of a novel virus, Hepatitis C virus.
News • Zika and chikungunya
Mosquito-borne viruses could cause stroke
A deadly combination of two mosquito-borne viruses may be a trigger for stroke, new research published in the The Lancet Neurology has found. University of Liverpool researchers and Brazilian collaborators have been investigating the link between neurological disease and infection with the viruses Zika and chikungunya. These viruses, which mostly circulate in the tropics, cause large outbreaks of…
Article • Blood poisoning
Exploring the importance and challenges of early sepsis diagnosis
On the occasion of this year's World Sepsis Day, we spoke with Elena Sukhacheva, Ph.D., director of medical and scientific affairs at Beckman Coulter, about the status quo and outlook on sepsis diagnostics. With the severity of sepsis symptoms, it’s easy to comprehend why it is invaluable to diagnose this disease properly and in a timely manner. Dr Sukhacheva takes an in-depth look at…
News • Under cover
Do masks give us a false sense of security? Probably not, says science
Existing limited evidence suggests that wearing face coverings to protect against COVID-19 does not lead to a false sense of security and is unlikely to increase the risk of infection through wearers foregoing other behaviours such as good hand hygiene, say researchers from the University of Cambridge and King’s College London.
Article • Corona management in Taiwan
Standing united against COVID-19
Despite its proximity to China, Taiwan contained COVID-19 successfully, without a lockdown or movement restriction measures introduced elsewhere. With few new cases reported, life almost returned to normal. Behind the scenes, however, efforts have continued to maintain that positive situation.
News • COVID-19
Novel viral transport media for testing of multiple infectious diseases
EKF Diagnostics, the global in vitro diagnostics company, announces that it has added a novel viral transport media for the safe sample handling and testing of multiple infectious diseases from a single swab to its product range.
Sponsored • Preventing needle-stick injuries
SAFETY Blood Collection Sets – Because safety is more important than ever
One of the most effective ways to protect yourself against needle-stick injuries (NSI) is to use safety products in your everyday work. In this area, Greiner Bio-One can offer you a comprehensive portfolio for a variety of requirements.
News • COVID-19
Ebola drug is effective against a key enzyme of coronavirus
Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published in the Journal of Biological Chemistry.
News • COVID-19 research
Clues to coronavirus’s vulnerability emerge from SARS antibody
An antibody recovered from a survivor of the SARS epidemic in the early 2000s has revealed a potential vulnerability of the new coronavirus at the root of COVID-19, according to a study from scientists at Scripps Research. The study, published in Science, is the first to map a human antibody’s interaction with the new coronavirus at near-atomic-scale resolution. Although the antibody was…
Article • Coronavirus disease research
Seeking a COVID-19 antidote: the potential of ACE2
As coronavirus disease COVID-19 continues to jet and alight invisibly around the globe, scientists now report that the virus has mutated to become two strains: the older ‘S-type’ appears milder and less infectious, while the later-emerging ‘L-type’, is more aggressive, spreads more quickly, and currently accounts for about 70 per cent of cases. Worldwide, medical researchers are exploring…
News • COVID-19 medication safety
New traffic light system to prevent coronavirus drug interaction
The University of Liverpool launched a new website featuring a traffic light system to aid the safe prescribing of experimental drugs being trialled against coronavirus (COVID-19). The site, created by the University’s Liverpool Drug Interactions Group, provides vital information on whether or not combinations of an experimental drug and co-medications are safe to prescribe. This is of…
News • Surprising discovery
Fatty liver disease can also affect lean people
Non-alcoholic fatty liver disease (NAFLD) is mostly diagnosed in overweight and obese people. However, severe forms of NAFLD can also be detected in rare genetic diseases such as lipodystrophy or in patients with HIV, putting them at a high risk for developing liver failure, diabetes and cardiovascular diseases. Norbert Stefan and colleagues have now detected a yet unknown cause of NAFLD in lean…
Sponsored • Product of the Month
Using safety products reduces the risk of needlestick injuries
If a health sector employee falls ill with a bloodborne illness, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with an NSI, is one of the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Don’t take the dangers posed by NSI lightly: get…
Article • Positive findings in PD-1 inhibitor immunotherapy
Hope increases for HIV cancer patients
Advances in antiretroviral therapy mean that today, people infected with the human immunodeficiency virus (HIV) can expect a healthy and long life. However, living with HIV does increase the risk of cancer. The reasons for this are multiple and include behavioural risk factors (smoking etc.) but many cancers can be attributed to the effects the virus has on the immune system, specifically its…
News • Tiny biomaterials
On the way to safer nanomedicine
Tiny particles that can fight cancer or that can easily pass through any interface within our body are a great promise for medicine. But there is little knowledge thus far about what exactly will happen to nanoparticles within our tissues and whether or not they can cause disease by themselves. Within an international research consortium, Empa scientists have now developed guidelines that should…
Article • IT
What data hackers get from hospital
When hospitals are hacked, the public hears about the number of victims – but not what information the cybercriminals stole.
News • Immune response alteration
Can a parasite infection protect against HIV?
Parasitic worm infections can reduce the susceptibility of immune cells to HIV infection, according to new University of Liverpool research. Some species of parasitic worm, such as the water-borne Schistosoma mansoni, have developed strategies to evade, skew and dampen human immune responses. This includes being able to alter the response of a type of immune system cell called a CD4+ T cell,…
Sponsored • Safety products
Abolish needlestick injuries
If a health sector employee falls ill with a bloodborne disease, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with a needlestick injury (NSI), is among the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Among the most effective ways to…
News • Global health
WHO updates list of essential medicines and diagnostics
The World Health Organisation's (WHO) Essential Medicines List and List of Essential Diagnostics are core guidance documents that help countries prioritize critical health products that should be widely available and affordable throughout health systems. Now, updated versions of the two lists have been published, focusing on cancer and other global health challenges, with an emphasis on effective…
Article • Boosting our immune surveillance
Antibodies PD-1 and PD-L1: a quantum leap in cancer therapy
Immuno-oncology is a therapy in which the body’s immune system treats a tumour. Dr Eric Borges, from the Research and Development Centre at Boehringer Ingelheim Pharma GmbH in Germany, explains why this is revolutionary. Unlike conventional cancer therapies, with immuno-oncology the tumour cell is not the direct target, it’s the patient’s immune system. The medication stimulates this to…
Article • Detecting migrant health risks
‘Refugees do not bring diseases to western shores’
The migrant population is fast growing and heterogeneous. Experts at a session held during the European Congress of Radiology (ECR 2019) concluded that radiologists can play a key role in detecting and differentiating related diseases. Migration is a growing phenomenon and has an impact on health, according to Jozef Bartovic from the World Health Organisation (WHO) in Copenhagen, Denmark.…
News • Gene-editing
CRISPR baby mutation significantly increases mortality
A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life, according to an analysis by scientists from UC Berkeley. The researchers scanned more than 400,000 genomes and associated health records contained in a British database, UK Biobank, and…
News • CRISPR
Could gold be the key to making gene therapy for HIV?
A proof-of-principle study shows that gold nanoparticles loaded with CRISPR and other gene-editing tools safely and effectively edited blood stem cells.
News • Sexually transmitted infections
New findings could improve STI vaccinations
In a new study, researchers from King’s College London have shown how skin vaccination can generate protective CD8 T-cells that are recruited to the genital tissues and could be used as a vaccination strategy for sexually transmitted infections (STIs), such as HIV or herpes simplex virus.
News • Fake pills
'Decoy' antibiotics dupe bacteria’s defences
Imperial medical students have helped to devise a new type of ‘decoy’ drug to tackle infections that are resistant to antibiotics. In lab tests on bacterial cultures, the new drug successfully killed a strain of drug-resistant bacteria. It works by delivering two antibiotics, one of which is effectively hidden. When the bacteria fight against the first ‘decoy’ antibiotic, this action…
Article • Blood transfusions
Donor organs become immunologically invisible
The safety of blood transfusions is questioned again and again by the mass media. Sometimes ‘bad’ blood causes infections; sometimes a transfusion leads to cancer years later. The fact is that transfer blood is subjected to the highest safety standards – there are very clear statutory regulations. Nonetheless, there will be shortages of ‘life’s fluid’ because, given increasing…
News • Gene editing
DNA “shredder”: a different kind of CRISPR
In the last six years, a tool called CRISPR-Cas9 has transformed genetic research, allowing scientists to snip and edit DNA strands at precise locations like a pair of tiny scissors. But sometimes, it takes more than scissors to do the job. Now, a collaborative international team has unveiled a new CRISPR-based tool that acts more like a shredder, able to wipe out long stretches of DNA in human…
News • Virology
Trapping viruses inside a cell: harmful or helpful?
Viruses are often used as vehicles for delivery in gene therapy because they’re engineered not to damage the cell once they get there, but neglecting to consider how the virus will exit the cell could have consequences. Some viruses use a molecule called heparan sulfate to help them attach to cells. The molecule, found in many different kinds of cells (including those from animal tissue), could…
News • X-ray crystallography
Seeing the unseeable life inside a virus
Researchers at Cardiff University have used x-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection. The new insight could help in the development of drugs and therapies for infections and further advance the exploitation of viruses for medical treatments. The first author of the study, Alex Baker from Cardiff University’s School of…
News • Dormant virus
Finding 'hidden' HIV in cells
Until now, researchers haven’t been able to accurately quantify a latent form of HIV that persists in patients’ immune cells. A new genetic technique is fast and 10 to 100 times more accurate than previous diagnostics. This hidden, inactive version of HIV embeds into cells’ genomes and can persist despite otherwise successful therapies – thwarting attempts to cure the infection. Using a…
Article • ß-D Glucan
New test for early fungal infection detection
At the National Reference Centre for Invasive Fungal Infections (Hans-Knöll Institute Jena) and the Institute for Hygiene and Microbiology, Würzburg University, Professor Oliver Kurzai and team utilise the fast and user-friendly β-D-Glucan Test, supplied by Fujifilm Wako Chemicals Europe GmbH, to check immunocompromised patients for signs of life-threatening, invasive fungal infections.…
Article • Medica 2018
The Czech med-tech market is thriving
The Czech Republic has a long tradition of ground-breaking medical innovations. At Medica 2018, the presence of Czech companies and traders underlined that medical devices and technologies from this country have continuing strength and value. Having recorded steady growth over the past few years, the Czech medical technology sector now produces a volume of around €870 million. 13,400 people…
Video • Controversial research
HIV and gene editing: beware of the butterfly effect, cautions expert
The claim of a chinese professor has caused quite a controversy: He Jiankui announced that he successfully modified human DNA to prevent two girls from contracting HIV. Upon the leak of this research, ethicists and scientists alike condemned Jiankui's gene editing in humans. West Virginia University Vice President and Executive Dean for Health Sciences Dr. Clay Marsh says that although “a lot…
Article • Evolving technique
Flow cytometry rises to new challenges
Flow cytometry has proved an invaluable diagnostic tool for leukaemia and lymphoma for almost three decades. Now, however, this is evolving in applications to seek out residual disease in cases and in fusion with molecular testing to advance its diagnostic potential. However, although recognised as fast, flexible and accurate, flow cytometry suffers from a lack of standardisation, according to…
News • Tick-borne infection
New techniques detects Lyme disease weeks before current tests
Researchers have developed techniques to detect Lyme disease bacteria weeks sooner than current tests, allowing patients to start treatment earlier. The new techniques can detect an active infection with the Lyme bacteria faster than the three weeks it takes for the current indirect antibody-based tests, which have been a standard since 1994. Another advantage of the new tests is that a positive…
News • Therapy
Could these special antibodies lead to HIV vaccine?
Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV. Researchers from the University of Zurich and the University Hospital Zurich have now shown that the genome of the HI virus is a decisive factor in determining which antibodies are formed.
News • HIV
Researchers date 'hibernating' HIV strains
Researchers have developed a novel way for dating "hibernating" HIV strains, in an advancement for HIV cure research in the province. The HIV cure research confirms that dormant HIV strains can persist in the body for decades.
News • Patient and staff safety
‘Any needlestick injury is one too many’
‘With Vacuette safety products you can minimise the risk of contamination and injury,’ the manufacturer Greiner Bio-One reports. ‘Needlestick injuries from contaminated puncture devices are the most common source of infection for diseases transmitted by blood or other bodily fluids and are still among the most common occupational accidents today. This is a serious danger!
News • Patient safety
Greiner Bio-One expands blood collection product range
The Vacuette Safety Winged Set is a new addition to Greiner Bio-One’s (GBO) range of safety products. GBO now offers its customers an even wider selection of safety blood collection sets. In response to high demand for Greiner Bio-One safety products, the existing range will be joined by the new Vacuette Safety Winged Set. As always, the aim is to provide functional, user-friendly and…
News • Therapy
A 'super' receptor that helps kill HIV infected cells
While treatments for HIV mean that the disease is no longer largely fatal, the world still lacks a true therapy that can eradicate the virus across a globally—and genetically different—population.
News • When the phosphate decides...
Defense against viruses or autoimmune disorder?
The first defense line of the body against virus infections is composed of so-called restriction factors. SAMHD1, one of such restriction factors, does not only play a role in the defense against viruses but also in the development of autoimmune disorders and cancer. The question of which effect SAMHD1 exertsin the cell is decided by addition or removal of phosphate groups.
News • New function assessment
Measuring immune cell response within minutes
T cells fight pathogens and tumors: Researchers from the Universities of Tübingen and Lübeck present a simple and fast method to rapidly assess their function. Due to its simplicity, reliability and versatility, it could be broadly implemented for basic research and in the clinical setting. Methods so far to test T-cell response were technically cumbersome and time-consuming and therefore only…
Article • Sexually-transmitted infections
Are Facebook and Twitter to blame for increasing STI rates?
While specific data remains limited on a possible connection between online forums and sexually-transmitted infections (STIs), this has become an area of increased focus. The subject was, for example, aired in April by one of the UK’s leading experts in the field, during the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), in Madrid. At the four-day event, Dr…
News • Tuberculosis
New blood test predicts TB onset up to two years in advance
A new blood test has been found to more accurately predict the development of tuberculosis up to two years before its onset in people living with someone with active TB, according to research published online in the American Journal of Respiratory and Critical Care Medicine, an American Thoracic Society journal. Those living with someone with active TB are at highest risk for developing the…
Sponsored • Innovative test
Diagnosis of bacterial vaginosis
Bacterial vaginosis (BV) is a common infectious disorder that affects millions of women worldwide. Women of all ages are at risk for BV and its complications, which include a greater susceptibility to sexually transmitted infections (STIs) such as herpes simplex virus and HIV. If left undetected and untreated, BV can increase a woman's risk of upper genital tract infections such as pelvic…
News • Feline findings
Cats could help in development of anti-HIV drugs
Feline AIDS is caused by the Feline Immunodeficiency Virus (FIV), which is very similar to the HIV-1 virus that affects millions of humans. While FIV does not infect humans, many groups research the virus to benefit cats, and perhaps more importantly, because of its many parallels with the AIDS virus. Despite the use of dedicated drugs, HIV-1 manages to thrive and multiply within the cell and…
Interview • Clinical practice
LC-MS/MS enters the medical laboratory
Over the last four years, Dr Thomas Stimpfl and his team have integrated mass spectrometry into routine analysis. The analytical technique liquid chromatography–mass spectrometry (LC-MS) combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analytical capabilities of mass spectrometry (MS). LC- and MS procedures were not originally developed for…
News • New data
WHO: High levels of antibiotic resistance found worldwide
WHO’s first release of surveillance data on antibiotic resistance reveals high levels of resistance to a number of serious bacterial infections in both high- and low-income countries. WHO’s new Global Antimicrobial Surveillance System (GLASS) reveals widespread occurrence of antibiotic resistance among 500 000 people with suspected bacterial infections across 22 countries.
News • Blood Donor Month
Things you should know about blood donation
Donating blood is a tangible way to help people who are struggling with serious health conditions, yet many people may not think about it or make time for it. In January – which the American Red Cross has dubbed National Blood Donor Month – blood bank supplies are typically among the lowest of the year, as many people have been traveling or busy with the holidays. Inclement weather can also…
News • Antiviral design
CAR-T gene therapy could provide long-term HIV protection
Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells not only destroyed the infected cells, they persisted for more than two years, suggesting the potential to create long-term immunity from the virus…
Video • In development
A more accurate tool to track new HIV infections
Researchers at the Duke Human Vaccine Institute have led an effort to develop a more accurate way to gauge the incidence of HIV infections in large populations, which will improve research and prevention strategies worldwide. The new method more correctly identifies new vs. long-standing infections – an important distinction for determining where to target public health measures and research,…
News • Infection research
Designer nanoparticles destroy a broad array of viruses
Viral infections kill millions of people worldwide every year, but currently available antiviral drugs are limited in that they mostly act against one or a small handful of related viruses. A few broad-spectrum drugs that prevent viral entry into healthy cells exist, but they usually need to be taken continuously to prevent infection, and resistance through viral mutation is a serious risk. Now,…
News • Prognosis and diagnosis
Deep insight into the heart
By no means are only elderly people at risk from heart diseases. Physically active individuals can also be affected, for example if a seemingly harmless flu bug spreads to the heart muscle. Should this remain undetected and if, for example, a builder continues with his strenuous job or an athlete carries on training, this can lead to chronic inflammation and in the worst case even to sudden…
News • Infectious disease
One in two people living with HIV in Europe is diagnosed late
The WHO European Region is the only region worldwide where the number of new HIV infections is rising. With more than 160 000 people newly diagnosed with HIV across the Region, including more than 29 000 new cases from the European Union and European Economic Area (EU/EEA), this trend continued in 2016. One reason for this worrying trend: over half (51%) of the reported HIV diagnoses happen in a…
News • Superbug MRSA
Unlocking the secrets of Staph's immune bypass
For years, medical investigators have tried and failed to develop vaccines for a type of staph bacteria associated with the deadly superbug MRSA. But a new study by Cedars-Sinai investigators shows how staph cells evade the body’s immune system, offering a clearer picture of how a successful vaccine would work.
Interview • From step-child to limelight
Virologists: Interdisciplinary and global cooperation is vital
Over recent years, virology, once medicine‘s step-child, moved into the limelight, pushed by impressive progress and pulled by globalisation-induced need for expertise in virus diagnostics and viral epidemics.
News • Study
Mushroom protein could be used in leukemia treatments
A protein found in the edible mushroom known as "shaggy ink cap" might be able to kill a type of leukemia cell, new research suggests.
Article • Antimicrobial resistance
Prudence is the cornerstone of prevention
Following a top level EU report showing antimicrobial resistance (AMR) remains high, Professor Mike Catchpole, Chief Scientist at the European Centre for Disease Prevention and Control (ECDC), has warned that stricter use of antibiotics is critical.
Interview • Infection control
Virologists are today’s universal necessities
Globalisation has been a defining term in this 21st century: with almost anybody able to visit any place at any time, diseases, viruses and bacteria can be travel companions. Thus virology is gaining increased attention. Professor Barbara Gärtner, President of the German Association of Virology, talks about the issues and challenges arising from this development.
News • Infections
Viruses Overheard Talking to One Another
Viruses may be stealthy invaders, but a study at the Weizmann Institute of Science reveals a new, chatty side of some: for the first time, viruses have been found communicating with one another. This communication – short “posts” left for kin and descendants – helps the viruses reading them to decide how to proceed with the process of infection. The research was reported in Nature.
News • Wound Management
Using fat to help wounds heal without scars
Doctors have found a way to manipulate wounds to heal as regenerated skin rather than scar tissue. The method involves transforming the most common type of cells found in wounds into fat cells – something that was previously thought to be impossible in humans. Researchers began this work at the Perelman School of Medicine at the University of Pennsylvania, which led to a large-scale, multi-year…
Article • Combatting infections
The global migration mapping project
Experts at a university in the United Kingdom have designed a large-scale data and mapping project that they hope will help in the global fight against infectious diseases.
News • Celebrity
The ‘Angelina Jolie’ Effect on breast cancer screening
Angelina Jolie received widespread media attention in 2013 when she told the public that she'd tested positive for BRCA1, a gene associated with an increased risk of breast and ovarian cancers, and subsequently had a double mastectomy. Now research shows a spike in genetic tests for breast cancer after actress’ public disclosure, but no corresponding increase in mastectomies.
Article • Molecular diagnostics
A one-step system for faster turnaround of hospital samples
A new molecular diagnostics system is revolutionising analysis of hospital samples across an area of northern Italy. The Greater Romagna Area Hub Laboratory has recently installed the Beckman Coulter DxN VERIS Molecular Diagnostics System and is already reporting improved workflow and quicker turnaround time for results.
News • Unsung Heroes
CARES Award helps people living with HIV/AIDS
Beckman Coulter Life Sciences is launching an international HIV/AIDS award at the 2016 conference for the African Society for Laboratory Medicine (ASLM) being held in Cape Town, South Africa (December 3 to 8).
Article • Frontline medical advances
Virology is now a key discipline
Virology is fast emerging as a key discipline within modern healthcare against a backdrop of a shifting global demographic and the impact of climate change.
News • Chronic Viral Infection
Inflammation triggers unsustainable immune response
Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development.
News • Melanoma treatment
Dermatology develops an effective immunotherapy against solid cancer
Melanomas account among the eight most frequent deadly cancers in Europe and Northern America. Two major clinical criteria separate melanomas from most other cancers: the risk to die from a melanoma is a question of being less or more than 1 mm – and not a question of cm. About 95% of patients with melanomas ≤0.5 mm in thickness are clinically cured by early detection and appropriate melanoma…
Sponsored • HIV
Experts Launch New Healthcare Trends Report
The HIV: The Long View initiative launches today with the release of an evidence-based report that examines the potential implications of future healthcare trends on HIV care and management in Western Europe.
Article • Research
First accurate simulation of a virus invading a cell
For the first time, scientists know what happens to a virus’ shape when it invades a host cell, thanks to an experiment by researchers at Penn State College of Medicine and University of Pittsburgh School of Medicine. Understanding how the virus shape specifically changes could lead to more effective anti-viral therapies.
News • Study
Link between Zika virus and severe joint condition at birth?
A study published by The BMJ provides more details of an association between Zika virus infection in the womb and a condition known as arthrogryposis, which causes joint deformities at birth, particularly in the arms and legs.
Interview • EU regulation
Stopping unsafe medical device production
According to Dr Peter Liese (CDU), speaker for health issues for the European People’s Party (EPP Group), the largest parliamentary group, this is an important step for Europeans who have long awaited appropriate consequences to follow scandals such as poor quality breast implants, stents or unsafe HIV tests. Due to extremely complex issues, it took several years to reach an agreement,…
Article • Disaster areas
Winners on the firing line
Jens Hahn MD is an Internal Medicine and Intensive Care Specialist who works with the international, independent, medical humanitarian organisation Médecins Sans Frontières (MSF in English: Doctors Without Borders). Here he describes his work in Afghanistan and South Sudan, and the use of rapid diagnostic tests in the field.
Article • Politics
Medics urged to organise refugee screening
Thousands upon thousands of humans have taken and are continuing to take flight from wars, persecution and economic stress, seeking the chance of survival in European and other countries. They arrive not only physically exhausted, but also in mourning for those killed in their own countries, or during hellish journeys – therefore many also suffer unimaginable mental traumas. Clearly they need…
News • EADV Symposium
Dermatologists and Venereologists discuss refugee crisis
The 13th Symposium of the European Academy of Dermatology and Venereology, which opened its doors last Thursday 19th May and took place in Athens, Greece, came to a conclusion yesterday, after more than 2,000 participants benefited from a series of scientific sessions focusing on the latest developments in Dermatology and Venereology.
First diagnosed case of Alzheimer’s Disease in HIV-positive individual
Georgetown University researchers are reporting the first case of Alzheimer’s disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer’s risk begins to escalate.
News • Key factor identified
Why is the immune system unable to combat HIV?
An international research group with essential participation of the Paul-Ehrlich-Institut, has identified NLRX1, a cellular factor of the human cell that is indispensable to the replication of Human Immunodeficiency Virus (HIV-1). This factor plays a key role in attenuating the innate immune system towards HIV-1. Until now, the significance of NLRX1 for the replication of HIV-1 and the…
News • Infectiology
Immune factor allows viral infections to become chronic
Many viral diseases tend to become chronic – including infections with the HI virus. In persons affected, the immune response is not sufficient to eliminate the virus permanently. Scientists at the University of Bonn have now identified an immune factor which is partially responsible for this. Their results give rise to hopes for new therapeutic approaches. The work, which included researchers…
News • Computational modeling
Analyzing genetic tree sheds light on disease outbreaks
Scientists have a new tool for unraveling the mysteries of how diseases such as HIV move through a population, thanks to insights into phylogenetics, the creation of an organism’s genetic tree and evolutionary relationships.
Article • Refugees
The major healthcare challenge
The refugee wave rolls on with no ebb in sight. For many, Germany remains their travel destination. In August and September alone, tens of thousands refugees arrived in Munich, presenting the Bavarian capital with a major challenge: How could the city provide initial medical care for everyone? While the German Asylum Procedure Act governs the appropriate procedures, in this unprecedented…
Diagnostics with birefringence
Nothing could be simpler: a drop of blood is placed on a special carrier substance; after a wait of a few minutes, the slide is placed on a device that emits polarised light thanks to an inexpensive polarisation filter. It is covered with a lid containing a second polarisation filter, which blocks the light from all materials except crystalline or materials with directional properties.
Article • Update
Hepatitis C management in Spain
Leading Spanish experts presented the latest developments in hepatitis C management in their country during the May meeting of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) in Seville. Report: Mélisande Rouger
News • Protein DART
New shock-and-kill strategy against HIV
A unique molecule developed at Duke Medicine, the University of North Carolina at Chapel Hill and MacroGenics, Inc., is able to bind HIV-infected cells to the immune system’s killer T cells. It could become a key part of a shock-and-kill strategy being developed in the hope of one day clearing HIV infection.
An antibody that can attack HIV in new ways
Proteins called broadly neutralizing antibodies (bNAbs) are a promising key to the prevention of infection by HIV, the virus that causes AIDS, say researchers at California Institute of Technology.
News • Fighting AIDS
Targeting HIV in semen to shut down AIDS
There may be two new ways to fight AIDS -- using a heat shock protein or a small molecule – to attack fibrils in semen associated with the human immunodeficiency virus (HIV) during the initial phases of infection, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
Needle exchange program prevented 120 new cases of HIV in 2 years
The District of Columbia's needle exchange program prevented 120 new cases of HIV infection and saved an estimated $44 million over just a two-year period, according to a first-of-a-kind study published today by researchers at the Milken Institute School of Public Health (Milken Institute SPH) at the George Washington University.
Article • Infectious diseases
Developing vaccines and nanotechnology
Vaccination remains one of the most efficient strategies against infectious diseases, often being the best protection against infections such as hepatitis B, or influenza. European Hospital reports on expert reviews of vaccines in the pipeline and the potential of nanomedicine given during the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) annual meeting in…
Agricultural intervention improves HIV outcomes
A multifaceted farming intervention can reduce food insecurity while improving HIV outcomes in patients in Kenya, according to a randomized, controlled trial led by researchers at UC San Francisco.
News • Aspergillus
ESCMID cautions that Europe is now a hotbed of global fungal resistance
ESCMID Fungal Infection Study Group (EFISG) argues that fungal resistance now represents a huge healthcare threat – with many cases remaining massively undiagnosed even in the developed world – and that there is a rising prevalence of the most invasive and deadly forms. Conversely, in the developing world we are seeing very treatable fungal infections killing huge numbers – half a million…
News • Market
EIB supports Cavidi’s development of HIV viral load monitoring device
The European Investment Bank (EIB) has provided a EUR 10 million long-term loan to Swedish biotech company Cavidi AB for developing a next generation automated testing device for HIV viral load. This is the first transaction under InnovFin Infectious Diseases, an innovative high risk-taking financial instrument recently established within the new generation of financial products for innovative…
News • HIV
Identification of a molecule that recognizes HIV in immune cells
In collaboration with colleagues from California and New York, researchers of the Paul-Ehrlich-Institut have identified a cytosolic receptor which enables cells of the immune system to recognize HIV and to trigger an immune response. The findings of the researchers may be a useful tool for creating an effective endogenous immune response against HIV and helpful to boost vaccine responses.
Test could identify resistant tuberculosis faster
The time needed to genetically sequence the bacteria causing tuberculosis (Mtb) from patient samples has been reduced from weeks to days using a new technique developed by a team at University College London (UCL). This could help health service providers to better treat disease, control transmission of this infection, and monitor outbreaks.
Sponsored • POCT
This market will boom
The turnover in POCT diagnostics will continue to increase substantially according to participants in an ‘In Vitro Diagnostic Products’ meeting held in Toronto, Canada last October. Sponsored by the German Institute for Standardisation, the event included participation by the DIN Standards Committee Medicine (NAMed; NA 063) and the Working Committee on Point of Care Testing (POCT) (NA…
News • News
Beckman Coulter launches diagnostics system
Beckman Coulter Diagnostics will be showcasing its new DxN VERIS Molecular Diagnostics System at ECCMID 2015 in Copenhagen.
Bio-Rad Laboratories and Beckman Coulter expands cooperation
Bio-Rad Laboratories, a global provider of life science research and clinical diagnostic products, announced that Bio-Rad is extending its agreement with Beckman Coulter and has named the company exclusive global distributor of Bio-Rad's Access HIV combo assay and the Access hepatitis C virus (HCV) assay in select geographies.
Interview • Health Apps
Can medical apps replace conventional medical diagnostics?
The question as to whether or not there is a point in using medical apps on private smartphones is being asked more frequently. Issues around medical diagnostics are among the key points here. We asked Prof. Dr. Dr. Norbert Gässler, Head of the Centre for Laboratory Diagnostics at the St. Bernward Hospital, Hildesheim, for competent advice. Interview: Walter Depner
Fighting HIV with antibodies
30 years after HIV was discovered to be the cause of the acquired immune deficiency syndrome AIDS, and despite intensive research, no vaccine or cure has yet been found. An international team of scientists, in collaboration with the German Center for Infection Research (DZIF) and the University Hospital of Cologne, has now tested a new generation of antibodies in humans for the first time. They…
Giant virus revealed in 3-D using X-ray laser
For the first time, researchers have produced a 3-D image revealing part of the inner structure of an intact, infectious virus, using a unique X-ray laser at the Department of Energy’s SLAC National Accelerator Laboratory. The virus, called Mimivirus, is in a curious class of “giant viruses” discovered just over a decade ago.
Article • IVD Market
Santa’s bag full of cash
We are seeing great priority shifts in China’s funding for R&D and manufacturing expansion. Even the agency responsible for selecting the recipients has changed, Jie Ren reports from the Beijing-based market analysis consultancy Whitney Research Inc. Report: John Brosky
Article • Infection Control
POCT accelerates diagnosis of STDs
Trichomonias, with an estimated 187 million cases, and Chlamydia with around 100 million, are the most prevalent sexually transmitted diseases (STDs), according to the World Health Organisation (WHO). There are approximately 36 million cases each of gonorrhoea and syphilis. HIV1/2 cases are around 34 million. Report: Cynthia Keen
Liquid biopsy
It sounds amazingly simple: a structured medical Seldinger guidewire is inserted via a peripheral venous catheter to ‘fish’ for circulating tumour cells (CTC) in the blood of cancer patients. Report: Bettina Döbereiner
Integration is key to tackling infectious diseases
World-renowned experts discussed the situation of predomonant epidemics at the International Roche Infectious Disease Symposium in Barcelona.
Redefining diagnostics
New molecular technologies to screen drug-resistant TB are replacing, for example, culture-based tests that are slow, require experienced personnel, and need stringent microbiological safety precautions.
New trial to combat gonorrhoea
A Birmingham hospital trust is to lead a major research study over concerns that one of the commonest sexually transmitted infections is becoming resistant to current treatment.
Tiny tools, big effects
imec, the European research centre for nanoelectronics, has linked with Johns Hopkins University in Baltimore, USA, to develop the next generation of highly miniaturised medical tools.
Curse or blessing?
A small prick to sample blood instead of complex pathological or other diagnostic procedures – this is how early cancer diagnosis will be in the near future. Blood tests to diagnose tumorous diseases early are already being researched for clinical use.
Fighting tuberculosis in Russia remains a challenge
Approximately 1.7 billion people worldwide carry Mycobacterium tuberculosis (MTB), i.e. about one-third of the population. The rate of new infections is highest in Africa, followed by certain Asian regions, including areas in Russia.
Chronic disease
There is a global shortage of doctors that is getting worse every year. With the demographic shift in many countries from a predominantly young to an increasing aging population, a steep increase in chronic disease is occurring.
An international impact on immunoassay
Snibe, the Shenzhen New Industries Biomedical Engineering Company Ltd., is a leading Chinese biomedical technology company dedicated to developing and manufacturing clinical laboratory equipment and in vitro reagents. Founded 18 years ago and a growing force in the Chinese market, the firm is based in Shenzhen, China’s fourth largest city, situated in Guangdong Province.
Goodbye to needlestick injuries
All hospital professions can be affected by injuries resulting from cuts and needlesticks, whether they are doctors, nurses or cleaners.
Investigating the HFN1 virus
Dutch virologist Ron Fouchier and his colleagues around the world stopped their research into the bird flu virus H5N1 for a whole year to allow an international debate surrounding the benefits and risks of their work.
Snibe makes an entry at EuroMedLab
Snibe, Shenzhen New Industries Biomedical Engineering Co., Ltd., is a leading Chinese biomedical technology company dedicated to developing and manufacturing clinical laboratory equipment and reagents.
The Robert Koch Foundation announces the 2013 laureates
Robert Koch Award 2013 goes to Jeffrey I. Gordon for pioneering studies of the human microbiome; Anthony S. Fauci receives the Robert Koch Gold Medal 2013 for outstanding scientific contributions to HIV research
POCT testing technology
Julian Baines, Group CEO of EKF Diagnostics Holdings plc, considers the present role of point of-care tests and their potential value to health services
Adoption of HIV nucleic acid testing and automation to spur market growth
Over 32% of HIV+ people in Europe remain undiagnosed. This large untapped pool and the development of novel nucleic acid test (NAT) and non-NAT technology based platforms offers growth potential for HIV diagnostics manufacturers.
Tangible Return on EU Investment in Global Health R&D
At the launch of the Policy Cures study ‘Saving Lives and Creating Impact: EU Investment in Poverty-Related and Neglected Diseases’ in Brussels today, DSW (Deutsche Stiftung Weltbevoelkerung) confirmed that EU funding for Global Health Research and Development (R&D) has a direct benefit on both developing countries and the European Union.
Molecular diagnoses will become routine
Molecular diagnostics is one of the most important technological advances in clinical diagnostics, seeing the €3.6 billion market grow 10% in constant currency (CC) in 2010 and predicted continual growth well above the diagnostic industry rates. The recipe for success in this field lies in three critical components: core technology, automation and menu. During our interview with Marc Meyer, the…
Drug-resistant tuberculosis fuels need for faster testing & development of new combination therapies
Johns Hopkins experts in the prevention and treatment of multidrug-resistant tuberculosis are calling for increased screening and more rapid testing of the 9 million people worldwide estimated to be infected each year with TB, and now at risk for this form of the highly contagious lung disease.
Growing presence of drug-resistant tuberculosis
Johns Hopkins experts in the prevention and treatment of multidrug-resistant tuberculosis are calling for increased screening and more rapid testing of the 9 million people worldwide estimated to be infected each year with TB, and now at risk for this form of the highly contagious lung disease.
European Congress of Radiology (ECR) 2012 opened
The European Congress of Radiology (ECR), the annual meeting of the die European Society of Radiology (ESR), started on Thursday in Vienna. 20,000 visitors are expected to participate in the congress which is one of the largest healthcare events worldwide.
New studies show which anti-HIV drug combinations work better than others
Using a mathematical formula that carefully measures the degree to which HIV infection of immune system cells is stalled by antiretroviral therapy, AIDS experts at Johns Hopkins have calculated precisely how well dozens of such anti-HIV drugs work, alone or in any of 857 likely combinations, in suppressing the virus.
Neurorad 2011 - Europe’s largest gathering of neuroradiologists
neurorad 2011 recently drew over 1,000 German neuroradiologists to Cologne, Germany, making this annual congress the biggest of its kind in Europe, as Professor Olav Jansen, President of the German Society of Neuroradiology, pointed out in his opening speech. Report: Alex Viola
Laboratory challenges in disasters and world tragedies
This May, IFCC WorldLab Berlin with its manifold scientific programme gives clinical lab physicians the opportunity to see over the rim of the tea cup of their working field. Within the congress theme ‘Healing the world’ comes an exciting lecture on laboratory work in third world countries and disaster areas.
A not so healthy glance at EU health
More than doubling over the last 20 years in most EU Member States, obesity has considerable implications for health, health systems and the economy. Over half our adult population is now overweight or obese, according to the joint European Commission and OECD report "Health at a Glance: Europe 2010".
Advancing POC diagnostics
Improvements in microfluidics and detection technologies are beginning to expand the range of point-of-care diagnostics beyond simple blood chemistry tests to sophisticated immuno-assays and molecular diagnostics. Though yet to see much adoption in European hospitals, these point-of-care (POC) diagnostics are coming into use in the USA, initially in emergency rooms and ICUs where fast results are…
AACC 2010
California, USA: 20,000 visitors and 700 manufacturers showing products in almost 2000 booths at the American Association for Clinical Chemistry (AACC) annual meeting (July 5-29, 2010) underlined the importance of this, the world’s largest gathering of clinical laboratory professionals.
Neurological diseases on the rise
„Diseases of the nervous system and the brain occur more frequently than cancer. According to recent calculations of health care costs, they represent a burden of 386 billion euros a year on European economies,“ says Prof. Gérard Said, newly elected president of the European Neurological Society (ENS) at the annual meeting in Berlin, Germany. „This is often greatly underestimated.“
Causes of death in AIDS patients
New research from the University of Bristol and a large group of international collaborators shows that Antiretroviral Therapy (ART) continues to dramatically reduce rates of mortality from HIV infection in high-income countries, such that non-AIDS-related deaths exceed AIDS deaths after approximately four years of taking ART.
International Day for Fighting Infection focuses on hospital infection control
Hospital acquired infections are the focus for the 3rd International Day for Fighting Infection, being marked on St. George’s Day (23 April), as experts meet in Florence to look at the evolution of infection control in hospitals.
The two faces of HIV/AIDS in the brain
The Opening Lecture at ECR always draws immense attention. On March 4th, it was the “First Lady of Radiology” as Congress President M. Szczerbo-Trojanowska called her, Professor Dr Anne G. Osborn, University of Utah, USA, who opened the event. The internationally renowned doctor of diagnostic neuroradiology spoke about “The two faces of HIV/AIDS in the brain” – a matter close to her…
Communicable disease programmes in Europe
One of the main topics at Health Forum Gastein 2009 was the way in which various healthcare systems struggle to cope with communicable diseases and their prevention. During the event, Dr Hans Kluge, Head of the Country Policies and Systems Unit, at the WHO regional office for Europe, spoke with Meike Lerner about omnipresent factors that work against effective TB and HIV/AIDS prevention…
Controlling infectious diseases in north-east Europe
Several years ago the Partners of the Northern Dimension Partnership in Public Health and Social Well-being (NDPHS) was organised to serve the Baltic Sea region. Due to the very different levels of public healthcare systems in north-east European countries, the NDPHS decided its main mission is to reduce social and economic differences and improve quality of life and demographic issues.
ESCAIDE 2009
The European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE) aims to strengthen and expand the network of specialists, share scientific knowledge and experience internationally, and provide a dedicated platform for EPIET/FETP (field epidemiology training programme) fellows to present their work.
European Practice Assessment wins Health Award 2009
The "European Health Award" presented this year at the European Health Forum Gastein (EHFG) goes to the European Patient Assessment (EPA) project. EPA is designed to improve the exchange of knowledge and experience by practical physicians in the area of primary care. Cross-border healthcare initiatives are distinguished every year with the European Health Award.
Threat of communicable diseases to become worse
The threat of communicable diseases will become even worse in the near future. At the European Health Forum Gastein, the European Union's leading health policy congress for experts and decision-makers, experts stressed that there are a number of risk factors which contribute to a growing risk of the spread of communicable diseases into Europe, namely into the European Union.
European Health Forum Gastein
600 international politicians, economists, scientists, NGOs and healthcare organisations will discuss the effects of the global economic crisis on European healthcare systems during this autumn's European Health Forum Gastein (EHFG).
International TB support from KfW Development Bank
Within the World Health Organisation European region three quarters of all new tuberculosis (TB) infections occur in Kazakhstan, Romania, Russia, Uzbekistan, the Ukraine and Turkey. The multi-resistant TB viruses, which can no longer be treated with conventional medication, are particularly common there.
Speeding up vaccine production
During the race to produce vaccines against evolving influenza viruses the slowness of their manufacture has turned producers more sharply towards cell culture technology. Using the traditional process, fertilised chicken eggs must first be inoculated with live flu virus, then the resulting egg-adapted virus must be purified and inactivated to produce trivalent inactivated virus (TIV), during…
Futures: HIV self-monitoring
HIV/AIDS has reached pandemic proportions. 35 million people are infected. Given the situation of hard pressed general practitioners (GPs) today, as well as geographical and other difficulties (as in Africa, for example), a new device that will enable HIV patients to monitor their own health and the effectiveness of treatments, without visiting their doctors so often, is indeed promising.
Delivering leading edge diagnostic tools to developing markets
Basic diagnostic x-ray services are a key component of primary health care delivery. However, two-thirds of the world's population is without access to it, according to World Health Organization (WHO) estimates. The WHO further estimates that there is a need for one diagnostic imaging machine for every 50,000 people. The World Health Imaging Alliance announced that it has cemented key…
New assay to identify acute HIV infections
A new HIV antigen-antibody combination assay, currently available in Europe, can be useful for high-volume screening to identify individuals with acute HIV infection, who would be missed by traditional HIV antibody tests, according to research presented by Johns Hopkins University, Abbott and others at the 16th Conference on Retroviruses and Opportunistic Infections (CROI).
Genome Structural Variation Consortium used Roche technology
Roches NimbleGen´s CGH microarray platform was used to generate the highest-resolution map of human genome copy number variation. Recent advances in microarray technology have led to the discovery of extensive copy number variation in the human genome, including DNA copy number gains (duplications), losses (deletions), and multiallelic or complex rearrangements.
Small device counts viruses in minutes
The machine 'qViro' which is the size of a coffee grinder will make virus counting much cheaper than traditional virus counting technology. The revolutionary new invention offers the potential to quickly muster and count the number of viruses in a sample in minutes - it is a portable, desktop instrument, powered from the USB drive of a computer - current competitors are the size of washing…
European researchers awarded for viral discoveries
German scientist Harald zur Hausen showed that oncogenic human papilloma virus (HPV) cause cervical cancer, the second most common cancer among women. Françoise Barré-Sinoussi and Luc Montagnier from France discovered HIV.
Drug resistant tuberculosis test within hours
GenoType® MTBDR plus, a new molecular test for multidrug-resistant tuberculosis has recently been approved in Europe. The test, developed by the Foundation for Innovative New Diagnostics (FIND) and Hain Lifescience, offers a fast solution to detect MDR-TB and XDR-TB at a reasonable price, a good condition for the application in poorer countries.
Vulvar cancer: a hidden disease
Vulvar cancer is the fourth most common cancer of the female genital tract. In 2008, roughly 3,460 cases of vulvar cancer will be diagnosed in the United States and about 870 will die of this cancer, according to the American Cancer Society.
French to the fore in HIV tests
During the XVII International AIDS Conference held in Mexico City this August, keynote speakers from Europe, Latin America and Africa addressed issues including the importance of early detection of HIV infection, the relevance of rapid testing for epidemiology studies, the use of Dried Blood Spots for routine viral-load testing in remote areas, and the experience of South Africa in routine…
Finn got 10 years for criminal HIV transmission
A 25 year-old Finnish man, who is HIV-positive, has been sentenced to ten years in prison for five counts of criminal HIV transmission, 14 counts of attempted criminal HIV exposure, and one count of rape.
Gleam of hope for people living with HIV
The “Project Connect”, a program designed to build Public Private Partnerships to combat HIV and tuberculosis in India recently recorded a huge success:
Better protection for nurses! - A global call to action
Provision of standard infectious disease precautions and safe workplaces for nurses all around the world are the main claims of a statement shaped during the International AIDS Conference by Physicians for Human Rights and the Association of Nurses in AIDS Care.
New treatment guidelines for HIV infection
An international panel of physicians has updated the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection after evaluating recent data, according to an article in JAMA, a theme issue on HIV/AIDS.
ESCAIDE 2008
For the second time the European Centre for Disease Prevention and Control (ECDC) in Stockholm, Sweden, invites to the European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE). The ECDC published now a forecast about expectations and the global hot topics of the international event in Berlin, November 19-21.
Russia: Fight against HIV
Russia has one of the fastest-growing AIDS epidemic in the world. One reason for this development is unsafe sex of addicts. Therefore sexual behaviour should be considered as an important component in the treatment of drug-dependent people to stop HIV-transmission.
India's world experts on TB
Every three minutes, two people living in India die of tuberculosis. This equates to approximately 370,000 deaths each year, and a staggering economic toll: an estimated US$300 million in direct costs and US$3 billion in indirect costs.
Nurses receive award for their work in tuberculosis
By putting the World TB Day slogan 'I am stopping TB' into action, 11 nurses have earned the 2008 ICN/Lilly Award, for their outstanding work in fighting tuberculosis (TB) and multi-drug resistant TB (MDR-TB)[1]. The award recipients come from six TB affected countries: from Kenya (Diana Jelegat Kipsoisoi), Lesotho (Likhapha Ntlamelle ), Malawi (Chrisie Bwazi, Rodwell Gundo and Shouts Simeza),…
Surgeons urged to 'think twice' before giving blood transfusions
The USA's National Institutes of Health aims to review blood transfusion safety
Surgeons urged to 'think twice'before giving blood transfusions
Hospitals are urged to tighten up on blood transfusions, following a growing number of reports on unrecognised risks from blood transfusions - and these are not the generally-known infection risks, such as HIV.
Personalised medicine?
'How do you treat the HIV-positive, diabetic, schizophrenic patient presenting with chest pain? By making the necessary information available for personalised medicine'
Europe's brain drain
Biotechnologist Dr Jens Meiler explains his reasons for emigration to America
HIV
By Tamar Jehuda-Cohen PhD, Biomedical Engineering Department, Technion Institute of Technology, Haifa, Israel
Rapid diagnostics from Inverness Medical
Inverness Medical acquired the Determine Brand of diagnostics was from Abbott laboratories in 2005. This move was part of their ongoing strategy to provide clinicians worldwide with a comprehensive portfolio of rapid, potentially life-saving diagnostic tools.
The SMARTube
SMARTube technology enables super-stimulation of lymphocytes, which leads to enhanced production of antibodies in vitro. This enables better and earlier detection of infections.
At a glance
Where are the most high-tech start-ups? That`s an easy one: Silicon Valley. But who comes in a close second? Surprisingly: Israel. Further: Israel ranks Number 1 in terms of availability of scientists and engineers and Number 2 in quality of higher education. The result of this impressive track record is a wide range of successful enterprises and products, particularly related to the life…
Development of potential Hepatitis C vaccine
The British Midlands' University of Nottingham discovered a possible vaccine for use in the treatment of Hepatits C. At the 161st. meeting of the Society for General Microbiology in Edinburgh, UK, a paper titled “Human Antibodies to Hepatits C Virus – Potential for Vaccine Design” was presented.
Setting international standards for TB care
By Professor Giovanni Battista Migliori MD, Director of the WHO Collaborating Centre for Control of Tuberculosis and Lung Diseases.
AACC emphasises preventive diagnostics
San Diego, California - 20,000 international physicians, scientists and other visitors travelled to the Annual Meeting & Clinical Lab Expo of the American Association for Clinical Chemistry (AACC) in July, and 750 exhibitors emphasised the increasing importance of this gathering
Libyan HIV Infection case becomes EU wide affair
At second instance a Libyan court sentenced five Bulgarian nurses to death. The healthcare workers are accused of allegedly infecting more than 400 children in Libya with HIV through contaminated blood products. Now Bulgaria will bring charges against 11 Libyan police officers for torturing the nurses into confessing that crime, that they allegedly did not commit.
Help for the helpers
Healthcare systems in Africa are facing a huge threat in their fight against AIDS - an increasing shortfall of nursing staff. Workers are either infected themselves or can no longer cope with the daily fight against the disease. Despite this, there is hope - the first wellness centre for healthcare workers, which provides medical and psychological help to nursing staff and their families, was…
TB - Tuberculosis
Discovery of cell receptor CCR5 might help tackle TB.
Verdict 'soon' in Libya
The five Bulgarian nurses and a Palestinian doctor, accused of intentional mass HIV infection, face their final court sitting on 31 October. A verdict is expected soon afterwards.
Pandemic panic sends feathers flying
AIDS, SARS and now H5NI; just a brief beginning or the end? As the virus moves towards Europe, and millions of birds are slaughtered, interest has risen in a Chinese herb, a patent-sharing controversy and drug stockpiling
Asylum seekers and healthcare
UK - Over 100,000 asylum seekers have been relocated throughout London and England's southeast, to spread the cost of their medical care.
Challenges for the new EU member states
Austria. 6-9 October - Challenges of the new EU Member States will be high on the agenda of this year's EHFG.
Tuberculosis blood test gains EU approval
TB causes three million deaths annually, ranking it higher than any other infectious disease. And TB has resurged in Europe. In August, the British Thoracic Society, British Lung Foundation and TB Alert highlighted its increase in over the last 15 years in the UK alone.
HIV
Medication regimes based on cocktails of antiretroviral drugs can reduce the AIDS virus to almost undetectable levels.
Award for HIV monitoring
The CyFlow and CyLab technique (e.g. for economical CD4/CD8 counting in HIV monitoring in developing countries) has received 1st prize in the Innovations Award 2003, given by the State Ministry of Economy, Dresden, Germany.