Researchers have created a first-of-its-kind immune cell atlas of the developing lung, revealing coordination between the immune and respiratory systems much earlier than previously thought.
Incidence of lung cancer among people who never smoked is rising. A new AI tool opens the door for opportunistic screening for this group, using existing chest X-rays in the electronic medical record.
A new survey by The BMJ reveals shortages of vital diagnostic tests for respiratory conditions, such as COPD and asthma, across some of the most deprived areas of England.
Heatwaves, wildfires, flooding: effects of climate change will further exacerbate breathing difficulties for millions of people living with lung conditions, new research finds.
Osaka Metropolitan University scientists have developed an advanced AI model that utilizes chest radiographs to accurately estimate a patient’s "true" age.
A new AI model finds that x-ray images collected during routine medical care can provide warning signs for diabetes, even in patients who don’t meet the guidelines for elevated risk.
A new device that combines microfluidics on paper, electrochemical transduction and immunoassays on magnetic nanoparticles is useful for easy and rapid diagnosis of lung diseases.
AI can use data from low-dose CT scans of the lungs to improve risk prediction for death from lung cancer, cardiovascular disease and other causes, a new study finds.
Photon-counting CT allows for a comprehensive, simultaneous evaluation of lung structure and function, something not possible with standard CT, according to a new study.
New research suggests that combining blood biomarkers with genomic information more accurately, cost-effectively predicts the risk of developing diseases.
People with strong legs are less likely to develop heart failure after a heart attack, according to research presented at the Heart Failure 2023 scientific congress in Prague.
A new study from Finland and Norway shows that babies born preterm are more likely to have asthma or chronic obstructive pulmonary disease, COPD, in adulthood.
Predicting a Covid-19 infection from the sound of a cough? Researchers found that technology using Machine Learning performed no better than simply asking people to report their symptoms.
Increasing accessibility of remote and home monitoring for patients with pulmonary diseases can help improve treatment and rehabilitation adherence, and support health systems and hospitals in tackling waiting lists. The various advantages of remote monitoring systems will be highlighted in a Medica session focusing on “Preventing chronic diseases with diagnostics and analytics”.
Artificial intelligence (AI) can be used to detect COVID-19 infection in people’s voices by means of a mobile phone app, according to research to be presented at the European Respiratory Society International Congress.
Dark-field radiography uses a part of X-rays that has hardly been considered so far to expand the spectrum of diagnostic imaging. At the ECR Overture, Theresa Urban presented the new method.
Researchers developed two concepts of wearable smart bioelectronic devices, materials for better real-time monitoring of a person’s health, including vitals.
Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis.
Scientists at the La Jolla Institute for Immunology discover new drug target for severe asthma and fibrosis.
Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the medications’ effectiveness. These interactions - seen for many drugs including those used to treat depression, diabetes, and asthma - could help researchers to better understand how drug effectiveness and side-effects differ between individuals. The study is…
Triage HF Plus, highlighted in the BCS conference session ‘Digital Innovation in Cardiology - What's new?’ is a digital heart failure care project that uses a customised algorithm to detect early signs of deterioration in patients with implanted devices. During her presentation ‘Digital solutions to identify worsening heart failure’, consultant cardiologist Dr Fozia Ahmed discussed the…
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune response in COPD patients.
Body composition information derived from routine chest CTs can provide important information on the overall health of people with chronic obstructive pulmonary disease (COPD), including their risk of all-cause mortality. This is the result of a new study, published in Radiology. COPD is a group of chronic, progressive lung diseases that affect about 30 million people in the United States alone.…
In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study, which was published in Immunity, may contribute to future treatments for Covid-19, among other diseases.
Chronic illnesses can have a dramatic impact on a patient's later life. An early diagnosis of such diseases opens up the possibility of taking medical action in good time.
Around 550 million people have chronic obstructive pulmonary disease (COPD), according to two University of Manchester medical students. The figure more than doubles the previous estimate of 251 million people with the illness linked to smoking by the World Health Organization (WHO) Global Burden of Disease Study. The University of Manchester students, Emily Hammond and Charles McDonald, made the…
Bacteria and other microorganisms in the digestive tract are linked with dozens of health conditions including high blood pressure, high blood lipids, and body mass index (BMI) according to research presented at ESC Congress 2020. “Our study indicates that microbiota might have an important role in maintaining health and could help us develop novel treatments,” said study author Dr. Hilde…
Researchers studying tissue removed from patients noses during surgery believe they may have discovered the reason why so many people with COVID-19 lose their sense of smell, even when they have no other symptoms. In their experiments they found extremely high levels of angiotensin converting enzyme II (ACE-2) only in the area of the nose responsible for smelling. This Enzyme is thought to be the…
Coronavirus can be identified automatically from sick patients’ lung X-rays using artificial intelligence (AI) developed at Brunel University London.
A smart shirt, developed by Canadian startup Hexoskin, has been successfully tested as a potential diagnostic modality for chronic obstructive pulmonary disease (COPD) at the Radboud University Medical Centre in The Netherlands. “COPD is a growing problem with around 64 million people suffering with the condition worldwide. When patients suffer an increase in their symptoms, such as coughing…
Researchers at National Jewish Health and dozens of leading institutions around the nation have proposed new criteria for diagnosing chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the United States. The proposal expands diagnostic criteria from a single measure of lung function to include environmental exposure, symptoms, and abnormal CT scans.
Spanish researchers in Valencia have identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. Presenting the research at the European Respiratory Society International Congress, Dr Francisco Sanz said the findings could enable doctors to test quickly for these biological markers when a patient is admitted to…
The latest study by the German Society for Haematology and Oncology (DGHO), ‘Prognosis for population-based morbidity for common cancers in Germany – impact on provision’ has made it clear that due to demographic developments in Germany and to medical advances in oncology, the requirements for cancer patients’ care are ever more diverse. The increase in newly diagnosed cancer patients is…
Researchers at Queen’s University Belfast have discovered a novel experimental treatment for chronic lung diseases that could improve the lives for people with Cystic Fibrosis (CF) and Chronic Obstructive Pulmonary Disease (COPD).
A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Albuminuria, Lung Function Decline, and Risk of Incident COPD: the NHLBI Pooled Cohorts Study,” Elizabeth C.…
Big Data can be a critical tool in helping clinicians develop advanced patient health risk assessment and stratification models as well as leading to a new level of patient empowerment. Professor Josep Roca outlined the benefits of Big Data in a laboratory context during the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference held in Mannheim, Germany,…
Innovative ‘artificial lungs’, which help the patients to breathe, offer less traumatic treatment for severe diseases such as acute respiratory distress syndrome (ARDS) or chronic obstructive pulmonary disease (COPD/AECOPD). Respiratory failure is one of the most frequent causes of ICU admission. It may occur inter alia in patients with ARDS, a dangerous condition when the respiratory system…
Nearly a quarter of patients with chronic ischaemic cardiovascular disease are dead or hospitalised within six months, reports a European Society of Cardiology (ESC) study published in the European Journal of Preventive Cardiology. “Coronary artery disease is the leading cause of death worldwide yet some patients appear to get lost in the system after their initial visit to a hospital or…
Older people who use steroid inhalers for asthma or chronic obstructive pulmonary disease (COPD) are more likely to suffer particular bacterial infections, according to a large study published in the European Respiratory Journal.
In a study conducted on mice, researchers found a receptor that could reverse inflammatory responses and combat chronic obstructive pulmonary disease (COPD) and other lung diseases.
Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.
Since lung diseases tend to be complex, imaging is a crucial diagnostic tool. While computed tomography has become the standard modality, which is frequently used outside hospital settings, specialised MRI diagnostics remains the preserve of large university medical centres.
Conventional therapy for ARDS patients and for patients with exacerbation of chronic obstructive pulmonary disease (COPD) has relied on invasive mechanical ventilation. Mechanical ventilation, however, has several major drawbacks: sedation has to be induced and the air being pressed into the lungs with positive pressure can damage the pulmonary alveoli or the diaphragm. Moreover, even maximum…
North West EHealth announced that its unique Linked Database System technology was used to deliver the world’s first digitally enhanced Randomised Controlled Trial (RCT) in the ground-breaking Salford Lung Study* (SLS). The study relied on bespoke software, developed by NorthWest EHealth and securely hosted within the NHS network, that integrated the electronic medical records of consented…
New research has found that a process initiated in white blood cells known as neutrophils may lead to worse outcomes for some patients with chronic obstructive pulmonary disease (COPD). The discovery may help identify patients at higher risk for COPD progression, who might also show little benefit from standard treatments.
Individuals with depression are more than twice as likely to have hospitalizations that might be preventable with timely outpatient medical care in the community, a new study finds.
It is estimated that half of all cancer patients suffer from a muscle wasting syndrome called cachexia. Cancer cachexia impairs quality of life and response to therapy, which increases morbidity and mortality of cancer patients. Currently, there is no approved treatment for muscle wasting but a new study from the Research Institute of the McGill University Health Centre (RI-MUHC) and University…
With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers at the University of Michigan Medical School have started to answer these questions by studying the microbiome of the lungs – the community of microscopic organisms that are…
Magnetic resonance imaging (MRI) and computed tomography (CT) provide important information on the symptoms and exercise capabilities of people with mild-to-moderate chronic obstructive pulmonary disease (COPD), according to a new study published online in the journal Radiology. Researchers said the findings point the way to better treatment for some COPD patients.
“I am very concerned about the impact that Angelina Jolie has on the media,” Walter Rocca, professor of epidemiology and neurology at the Mayo Clinic in Rochester, Minnesota, stated. He wasn’t hinting to Jolie’s acting choices or waifish silhouette, but to the confusion surrounding her decision to remove her ovaries to prevent ovarian cancer. By Mélisande Rouger
Given the increasing focus on telehealth and telecare services aimed at improving long-term patients’ living conditions and save costs, numerous pilots in various countries have been conducted for proof of concept purposes. Among these, the United Kingdom’s ‘Whole System Demonstrator’ (WSD) programme is the largest randomised controlled trial. Set up by the English National Health Service…
Research being conducted in the United Kingdom is focusing on techniques to help improve the weaning process for patients coming off mechanical ventilation in hospital intensive care units. Report: Mark Nicholls
Smoking prevalence is 50% higher in this group; Researchers say that more effort is needed to help them quit.
Screening for lung cancer saves lives. This fact has been documented by outcomes of the U.S. National Lung Screening Trial (NLST) which showed a 20% reduction in lung cancer-specific deaths in patients who had a chest CT screening. What is controversial is how to establish the radiology resources needed to perform exams for all the people who need it and then how to pay for the exams.
Despite some decline in cigarette consumption during the last decades, chronic obstructive pulmonary disease (COPD) remains a major public health concern. COPD is among the top five leading causes of chronic morbidity and mortality in the US and in Europe. Nevertheless, COPD is substantially underdiagnosed.
“On a day-to-day basis, each of us in thoracic imaging is dealing with a large number of patients with pulmonary metastasis or lung cancer,” said Christoph Engelke, MD. “These patients have been targeted by different chemotherapies and surgical therapies. Yet the prognosis in advanced lung cancer stages has not been changed.”
Will MRI become routine modality? Today, thoracic MRI is rarely performed in Europe. But this will change over the next decade, predicts Professor Hans-Ulrich Kauczor, Medical Director of the Radiology Clinic at University Hospital Heidelberg. He expects Germany to be at the forefront of this development because MRI technology, despite the high costs, is already widely used here and because CT…
Many smokers continue to use tobacco despite high taxes and drastic health warnings. Indeed, in industrialised countries, tobacco-related mortality rates or illnesses are increasing. These include chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in adults – and rising.
Morbid obesity is a chronic, lifelong, multifactorial, constitutional disease with negative medical, psychological, physical, social and economic side-effects. Obesity-related secondary diseases are Type 2 diabetes mellitus (T2DM), cardiovascular diseases such as hypertension or sleep apnoea. Report: Holger Zorn
This March, Heinz-Dieter Hilgers arrived for his once-monthly check-up at Ruhrlandklinik in Essen. Last June, his situation was far less relaxed. Suffering chronic obstructive pulmonary disease (COPD) for almost two years, he had been listed for a lung transplant since April 2009. During his wait for an organ, his illness increased.
Renewing Health is the Veneto Region’s response to the third Call of Proposals by the European Information Communication Technology Policy Support Programme (ICT-PSP). The project, which falls under the ICT-PSP financing plans, aims to facilitate the use of ICT-based solutions and services for citizens, the government, and businesses, as well as aiding their diffusion throughout Europe.
The lungs had to be regarded as the black hole for MRI for a long time. However, since the introduction of substantial improvements in hardware and scanner technology, there is certainly light at the end of the tunnel. MRI offers two main advantages for the diagnostic pathways for pulmonary diseases applied today.
In November 2009 about 150 leading infectious disease researchers gathered in Berlin for the National Forum for Innovation in Medicine. During the meeting, Professor Antoni Torres MD (Hospital Clinic-Ciberes, University of Barcelona) gave Meike Lerner insights into community acquired pneumonia research projects and findings
Investigating the appropriate use of procedures to open narrowed coronary arteries, e.g. angioplasty and stenting, researchers at UCSF (University of California, USA) found that less than 50% of Medicare patients had documented non-invasive stress testing prior to elective percutaneous coronary intervention, or PCI (clinical name for these procedures).
Experts starts to identify nutrition's components that might support the fight against diseases. Recently researchers from John Hopkins Medical School found that a decrease in lung concentrations of NFR2-dependent antioxidants, key components of the lung's defense system, is linked to the severity of chronic obstructive pulmany disease (COPD) in smokers.
Drug access by older citizens varies widely across 25 EU member countries, according to a new study by IMS Health. Per capita usage of drugs to treat Alzheimer's disease in the five EU countries where utilization was highest was 20 times greater than in the five lowest-use countries.
Hospital admission might probably determine the severity of heart failure. By analysing data from 260 hospitals across the United States researchers created a model to reduce in-hospital mortality and more quickly identify triage methods and treatment decisions.
USA - A new tuberculosis vaccine successfully tested at the University of North Carolina (UNC) is easier to administer and store and just as effective as one commonly used worldwide, according to research published in the Proceedings of the National Academy of Sciences.
Encouraged by the success of the Dual-Source CT system Somatom Definition with two X-ray tubes that simultaneously generate different energies, Siemens Healthcare has already developed six specific dual energy applications. At the ECR 2008, the company presents four new applications that simplify the diagnosis of diseases of the heart, brain, lungs and extremity joints.
Since its early beginnings in Europe, during the polio epidemics of the 1950s, intensive care medicine has grown to become a specialty in its own right and the intensive care unit (ICU) occupies an increasingly important position in every hospital. Intensive care doctors are responsible for the management of very sick patients often with multiple and complex disease processes, and ICUs are now…
Detroit based Delphi Medical Systems is a world-class provider of technology, products, and product development and manufacturing for many major sectors of the medical industry. Amongst their latest technologies on show at Medica (Hall 11) is the Delphi Portable O2, a light weight oxygen supply for patients with respiratory diseases or other illnesses requiring supplemental oxygen such as chronic…
By Paolo Montuschi MD, of the Department of Pharmacology, Faculty of Medicine, Catholic University of the Sacred Heart, Rome, Italy.
Belgium and United Kingdom - Two researchers, Dr Charles Pilette, currently at the Pneumology Department, University Hospital of Louvain, St-Luc, Belgium, and Dr William Man, who is completing specialist clinical training in Respiratory Medicine and General Internal Medicine, in London, have received this year's awards for research into Chronic Obstructive Pulmonary Disease (COPD), granted by…
A report from the 2nd Telemedicine Forum, organised by Tele Medical Systems AG (TMS).
Dr Christiane Eickelberg, of the University of Giessen Lung Centre (UGLC), outlines the centre's research projects, aims and academic offerings
From burden to therapy. By Andrea Rossi MD, Director of the Respiratory Division at Bergamo General Hospital Bergamo, Italy, and Chair of the Scientific Committee of the European Respiratory Society
Telemonitoring can improve survival and increase quality of life in patients with chronically diseases.
The Vest Airway Clearance System (which is technique independent and treats all lobes of the lungs simultaneously) helps to mobilise pulmonary secretion via high-frequency chest wall oscillation.
Breathlessness, the most common symptom in patients with chronic obstructive pulmonary disease (COPD), greatly reduces their ability to participate in day-to-day activities.