Do laboratory tests using blood-based biomarkers (BBB) represent the next type of universally recommended screening tests for Alzheimer's disease (AD)? Experts curb the high expectations for this type of diagnostic tool.
Machine learning (ML) for personalised care, large language models for empathy training of cardiologists, wearable sensor data for better screening, and more: Digital technologies hold great potential to improve diagnosis and treatment of patients with atrial fibrillation (AF). At the ESC 2024 cardiology congress in London, four experts explored the benefits of new solutions and pointed out…
Researchers have developed an AI tool that creates synthetic yet medically accurate models of fibrotic heart tissue (heart scarring), aiding treatment planning for atrial fibrillation (AF) patients.
A network of artificial neurons imitating the human brain could help identify patients at risk of a serious arrhythmia from an ECG and avoid many cases of sudden cardiac death, a new study suggests.
Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…
Nuclear cardiology is a specialised field in nuclear medicine that evaluates the heart function to help diagnosing conditions such as coronary artery disease and to assess treatment efficacy, whilst minimising invasive procedures like biopsies. More recently, clinicians have increasingly opted for nuclear imaging over endomyocardial biopsy to diagnose cardiac amyloidosis, allowing for earlier…
Scientists have now discovered that the heart has its own complex nervous system – a 'mini brain', if you will – that is crucial to controlling its rhythm.
Surgeons have performed an unprecedented procedure on a two-year-old child diagnosed with scimitar syndrome. This marks the world’s first successful application of the “Double-decker Technique”.
Catheter ablation of atrial fibrillation is an important treatment option for heart rhythm maintenance and symptom reduction. Now, an international consensus statement reflects new techniques.
Combining a biological heart and a silicone robotic pump, researchers created a biorobotic heart that beats like a real one, with a focus on a valve on the left side of the heart.
Scientists have developed an ingestible device that can safely monitor vital signs like breathing and heart rate from inside humans, providing accessible and convenient care for people at risk of opioid overdose.
New research led by Brigham and Women’s Hospital unveils that women who struggle with getting enough sleep might be at greater risk of developing hypertension, or high blood pressure.
Scientists have developed a tool to create a digital replica of an individual's heart, which could inform the diagnosis and treatment of cardiovascular diseases.
More than 40% of women report anxiety four months after a cardiac arrest compared with 23% of men, according to research presented at ESC Acute CardioVascular Care 2023.
Monitoring the proper blood supply to the brain could be used to prevent or even treat neurological diseases. A new technique called πNIRS aims to do just that.
Increasing accessibility of remote and home monitoring for patients with pulmonary diseases can help improve treatment and rehabilitation adherence, and support health systems and hospitals in tackling waiting lists. The various advantages of remote monitoring systems will be highlighted in a Medica session focusing on “Preventing chronic diseases with diagnostics and analytics”.
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
Atrial fibrillation screening using conventional smartphones more than doubles the detection and treatment rate in older people compared to routine screening, new research finds.
A special type of MRI found lung abnormalities in patients who had previously had COVID-19, even those who had not been hospitalized with the illness.
For people with atrial fibrillation, one of our most common cardiac disorders, dementia risk is elevated.
An ECRC research team has introduced CRISPR-Cas9 into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.
A tiny ‘pop-up’ sensor monitors the electrical activity inside heart cells. The device could provide new insights into cardiac diseases, including myocardial infarction and arrhythmias.
Wearables are a trend in respiratory care and many products are being developed to monitor patients remotely. But how much can these tools really help clinicians? An Italian expert discussed current solutions and challenges to their development.
A study found that women who contract Covid-19 during pregnancy are at significantly higher risk of developing pre-eclampsia. In their study, researchers said their systematic review shows that women with SARS-CoV-2 infection during pregnancy had 62% higher odds of developing preeclampsia than those without the infection during pregnancy.
A nationwide US study has shown that the rate of opioid-related cardiac arrests has steeply risen and is now on par with the rate of cardiac arrest from other causes. The research is presented at ESC Congress 2021. Opioid use disorder, which includes dependence and addiction, affects more than two million people in the US, while opioid overdose is the leading cause of death for those aged 25 to…
Women are missing out on appropriate cardiac care because guidelines and medications often fail to take into account gender and conditions that specifically affect the female population. Women are also underrepresented in clinical trials for new cardiac therapies.
For the first time, a prospective, international study has shown that chest pain caused by problems with the very small vessels supplying blood to the heart is an important health problem that increases the risk of heart attacks, stroke and death due to cardiovascular reasons. The study, which is published in the European Heart Journal, recruited 686 patients from 14 institutions in seven…
Physicians are increasingly using software to automatically evaluate Holter ECG signals in adult patients, but so far, no software has been developed for children. Cardiomatics and the Medical University of Warsaw are on the way to a breakthrough in paediatric cardiology. They are developing an international tool for automatic assessment, analysis, and interpretation of electrocardiographic…
Self-organizing heart organoids – developed at the Austrian Academy of Sciences – are also effective injury- and in vitro congenital disease models. These “cardioids” may revolutionize research into cardiovascular disorders and malformations of the heart. The results are published in the journal Cell.
Omega-3 supplements are associated with an increased likelihood of developing atrial fibrillation in people with high blood lipids. That’s the finding of a study published in European Heart Journal - Cardiovascular Pharmacotherapy, a journal of the European Society of Cardiology (ESC).
A new photonics device currently in development aims to reduce unnecessary disabilities by improving the instant, real-time monitoring of newborn babies with harmless light particles.
Smart speakers, such as Amazon Echo and Google Home, have proven adept at monitoring certain health care issues at home. For example, researchers at the University of Washington have shown that these devices can detect cardiac arrests or monitor babies breathing. But what about tracking something even smaller: the minute motion of individual heartbeats in a person sitting in front of a smart…
Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an ongoing need for alternative therapies. With new developments in cardiac assistance systems, we can delay the need for a transplant – or even eliminate it altogether,” says Professor Yves Perriard, head of EPFL’s…
Engineers at EPFL’s Center for Artificial Muscles have developed a silicone aorta that can reduce how hard patients’ hearts have to pump. Their breakthrough could offer a promising alternative to heart transplants. “Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an…
An up-and-coming gene therapy for blood disorders. A new class of medications for cystic fibrosis. Increased access to telemedicine. These are some of the innovations that will enhance healing and change healthcare in the coming year, according to a distinguished panel of clinicians and researchers from Cleveland Clinic. In conjunction with the 2020 Medical Innovation Summit, Cleveland Clinic…
Michigan State University researchers have created for the first time a miniature human heart model in the laboratory, complete with all primary heart cell types and a functioning structure of chambers and vascular tissue.
Pupil size predicts death and hospital readmission in patients with heart failure, according to new research. “Our results suggest that pupil area is a novel way to identify heart patients at elevated risk of death or hospital readmission,” said study author Dr. Kohei Nozaki of Kitasato University Hospital, Kanagawa, Japan. “This provides an opportunity to intervene and improve outlook.”
Biomedical engineering researchers at Texas A&M University designed a medical device that mimics blood vessels to design and monitor drugs for patients with clotting disorders. This approach could be especially beneficial for pediatric patients. Unlike what a biology textbook may show, blood vessels are not straight cylinders. They are tortuous, meaning they have complex curves, spirals and…
Siemens Healthineers announced today that it is now shipping worldwide its laboratory-based total antibody test1 to detect the presence of SARS-CoV-2 IgM and IgG antibodies in blood.
At least half of all patients who survive treatment in an intensive care unit will experience at least one of a triad of problems associated with post-intensive care syndrome, or PICS, and this may be true for people recovering from COVID-19 following ICU care. PICS can manifest as problems with physical function, cognition and mental health, according to a fact sheet from the American Thoracic…
Getting a good night’s sleep is important and insufficient sleep has been linked to poor health in many studies. Analysing data collected from wearable trackers, researchers from the SingHealth Duke-NUS Institute of Precision Medicine (PRISM) and the National Heart Centre Singapore (NHCS) recently demonstrated that chronic sleep deprivation is associated with increased cardiovascular disease…
Researchers at National Jewish Health and dozens of leading institutions around the nation have proposed new criteria for diagnosing chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the United States. The proposal expands diagnostic criteria from a single measure of lung function to include environmental exposure, symptoms, and abnormal CT scans.
Patients with the rare Loeys-Dietz syndrome suffer from aortic enlargement which may result in sudden over-expansion and a fatal aortic tear. In order to prevent this from happening, an aortic prosthesis must be implanted. A team of vascular surgeons at the University Hospital of Zurich was one of the first in the world to risk undertaking this life-saving operation on a child as an emergency…
Researchers at the University of Strathclyde have developed an innovative, low cost test for earlier diagnosis of sepsis which could save thousands of lives. The simple system for sensitive real-time measurement of the life threatening condition is much quicker than existing hospital tests, which can take up to 72 hours to process. Using a microelectrode, a biosensor device is used to detect if…
How can we detect the first signs of disease as early as possible? Could closer investigation at the cellular level help to quickly prevent disease progression through appropriate treatment? The European Union is now investing a million euros over a one-year period to devise the plan for a fundamentally new approach to understanding the constant changes within cells and their relationships to one…
Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart — a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.
Transgender individuals may be at higher risk for myocardial infarction and death due to cardiovascular disease, according to several studies. This increased risk may be due to the hormone therapy that transgender patients take for masculinization or feminization. A review authored by Michael S. Irwig, MD, associate professor of medicine at the George Washington University (GW) School of Medicine…
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers at the Cincinnati Children’s Heart Institute report in the journal Circulation testing a manufactured peptide called pUR4 to block the fibronectin protein in human…
The heart is capable of terminating arrhythmias itself after local gene therapy, potentially avoiding the need for patients to undergo painful electric shocks, according to a proof-of-concept study presented today at EHRA 2018, a European Society of Cardiology congress. Atrial fibrillation is the most common heart rhythm disorder (arrhythmia). Treatment aims to restore the heart’s normal rhythm…
The Clinica Creu Blanca Diagnostic Group in Barcelona, Spain, is the first clinic in Europe to use Canon Medical System’s new Celesteion PET-CT Scanner. Dr. Xavier Alomar, Head of the Diagnostic Imaging Department at the Clinic, explains how the new system has opened up a large field of diagnostic possibilities for the Group in Metabolic Medicine in Oncology, Neurology, Cardiology and…
Stopping abdominal wall bleeding with contrast-enhanced ultrasound was just one of the exciting developments in CEUS presented at the Bubble Conference 2017 in Chicago. When you cut your finger you apply pressure to the wound until the bleeding stops. Professor Dirk-André Clevert from the Institute for Clinical Radiology at the Ludwig Maximilian University Hospital, Munich, Germany, remembered…
Modifying a DNA sequence to alter a cell to cure a disorder, prevent a genetic disease being passed on to next generations, or to use genetic modification as a way to diagnose a virus: yes, these tasks are possible. The recently discovered CRISPR technique can do it all.
Researchers who studied beer drinkers at the Munich Oktoberfest have found that the more alcohol consumed the higher was the likelihood of developing abnormal heart rhythms called cardiac arrhythmias.
Patients with locally advanced rectal cancer have been treated with intra-operative radiotherapy (IORT) for over twenty years. Partly due to this type of radiation, survival rates in a group of patients considered to have inoperable cancer changed dramatically from five to 70 percent.
SIGNA Pioneer, a new 3.0 T Magnetic Resonance Imaging (MRI) system, embodies the exploration and expansion of modern medical imaging and blazes a trail to the future of MRI. Dr. Ahlers, general manager of radiomed, shares his experience with SIGNA Pioneer recently installed at radiomed practice in Wiesbaden, Germany – one of the first installations worldwide.
The conventional 12-lead ECG has certainly proved its worth in displaying rhythm disorders or ischemia. Nevertheless, as the display possibilities of a 12-lead ECG are limited to only about 110 degrees of the heart, an exact location of a cardiac event often cannot be determined.
As new cardiac genetic testing panels become available, cardiologists have been warned not to lose sight of the importance of comprehensive clinical evaluation. While genetic testing is helping to identify more people at risk of inherited conditions, experts stress they are only part of the diagnostic toolkit.
Philips Minicare delivers rule-in/rule-out readings for heart attacks in 10 minutes. It takes a lot of hard work to make things easy. Biomedical experts at Royal Philips have spent more than 10 years developing a simple test for the emergency department that, in less than 10 minutes, may indicate whether a patient suffering chest pains is having a heart attack.
Publicly insured Americans who undergo lung transplantation for cystic fibrosis fare markedly worse in the long run than both publicly insured patients in the United Kingdom and privately insured Americans, according to the results of a study conducted by researchers from Johns Hopkins in Baltimore and U.K. colleagues working in that nation’s government-funded National Health Service.
Cardiomyopathy is a disease with many faces, a 'chameleon', according to Professor Jeanette Schulz-Menger. MRI benefits and potential should be communicated better and to a wider clinical audience. Report: Axel Viola
Someone once described the fusion of positron emission tomography (PET) and magnetic resonance imaging (MRI) as a great technology looking for an application. Report: John Brosky
Congenital heart defects are the most common congenital disorders found in newborns – around one in a hundred babies are affected. This type of heart defect can be reliably diagnosed with ultrasound, usually during the detailed foetal scan carried out halfway through the pregnancy. Report: Brigitte Dinkloh
Ultrasound Contrast Agent SonoVue usable in case of recent acute coronary syndrome or clinically unstable ischaemic cardiac disease.
In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.
Despite the availability of cardioversion, ablation and medications to treat AF, outcomes are often poor because it is unclear which patients will benefit most. A new classification of atrial fibrillation (AF) by electrocardiogram (ECG) is set to be developed by European experts to aid personalised management of this devastating condition.
The insight that psychological, social and environmental conditions affect a person’s health is insufficiently considered in medical training and in the every-day diagnosis and treatment of patients.
The Catharina Hospital (Eindhoven, the Netherlands) and Royal Philips (NYSE: PHG, AEX: PHIA) today announced the results of a clinical study involving the treatment of 136 patients with complex heart rhythm disorders such as atrial fibrillation (AF).
Artificial hearts, originally designed to bridge the time on the waiting list for a heart transplant, in recent years have increasingly become an independent treatment option for patients with chronic heart failure (HF).
Artificial hearts, originally designed to bridge the time on the waiting list for a heart transplant, in recent years have increasingly become an independent treatment option for patients with chronic heart failure (HF). Interview: Bettina Döbereiner
More anatomy details, real-time visualisation of catheter movement, and reduced exposure – MRI has promising potential in rhythmology, explain Professor Matthias Gutberlet and PD Dr Christopher Piorkowski, at the Heart Centre, University Hospital Leipzig, Germany.
The biggest cause of death for most adult women in industrialised nations is coronary heart disease (CHD). Why the disease affects the genders differently is still not fully understood. European Hospital Editor Brigitte Dinkloh asked Professor Rafaelle Bugiardini MD FESC, from the Department of Internal Medicine Department, University of Bologna, whether he could explain the reasons and what…
Imaging of the chest is the most common radiological examination worldwide. With the incidence of respiratory problems and lung cancer growing, all radiologists should be familiar with the appropriate imaging protocols. In a field dominated by chest x-ray (CXR) and CT, controlling radiation dose is mandatory.
In 2012, Chicago’s Children’s Memorial Hospital will be in transition, with a change of name as well as location, when its top class technology, physicians, scientists, staff and patients transfer to a new state-of-the-art complex three miles away.
Acute myocardial Infarction (AMI) is a major cause of death and disability. Worldwide, one in eight patients die of an ischemic heart disease. Its rapid and accurate diagnosis is critical for the initiation of effective evidence based medical management, including early revascularization, but is still an unmet clinical need. The gradual implementation of high-sensitive cardiac troponins (hs-cTnT)…
Royal Philips Electronics provided clinicians from across the globe with a glimpse of future innovations designed to advance cardiac care, including the current management of cardiovascular disease (CVD) and associated cardiac conditions, during the 2011 Congress of the European Society of Cardiology (ESC).
Siemens Healthcare presented solutions for sustainable cardiovascular care at the European Society of Cardiology (ESC) congress in Paris, France, under the motto "Are you ready for the long run?". This includes all modern imaging technologies, in-vitro diagnostics, IT solutions and consulting services.
A hefty debate on controversial issues in cardiology is the definite intent of Congress President Professor Michel Komajda and the ESC 2011 congress organisers. To that end, he plans to open the event with a focus on disagreements among cardiologists over treatment methods. This is not the only promise of a lively meeting for congress participants, as Prof Komajda explained in conversation with…
A modern-day childhood totally differs from what was common just a few decades ago. It is mostly spent sitting -- at school desks, in front of TV screens or before computer monitors – all combined with the sweet temptations of the kid’s food industry. According to a WHO worldwide estimate, an estimated 10% of school-age children between five and 17 years old are overweight or obese. The…
Research introduced at SNM’s 58th Annual Meeting may lead to much-needed cardiovascular disease screening for diabetic patients at risk of ischemic heart disease, a disorder marked by significantly reduced blood flow in the heart. Ischemia of the myocardium, or cardiac muscle, can signal diminished oxygenation of the heart tissue and trigger a heart attack if left untreated.
This April the 77th Annual Meeting of the German Cardiac Society (DGK) presented over 300 events with 1,800 speakers, covering the entire spectrum of cardiovascular diseases, from fundamental research to clinical routine. Professor Gerd Hasenfuss, Director of the Department of Cardiology and Pulmonology and Chair of the Heart Research Centre in Gottingen, particularly requested a focus on …
Biomarkers as the key to prevention and early detection were the subject this autumn at the 7th Annual Congress of the German Society for Clinical Chemistry and Laboratory Medicine (DGKL) in Mannheim. For the DGKL president Professor Karl J Lackner MD, Director of the Institute for Clinical Chemistry and Laboratory Medicine at Johannes Gutenberg University, Mainz, the topic is of increasing…
Today in most countries of the world almost 50 % of patients in hospital for a cardiac condition began their treatment as emergency cases: chest pain at home . . . a cardiac arrest in the street. Thus, according to Dr Peter Clemmensen, of the 22 million hospital admissions in Europe each year for acute cardiac events, more than 10 million of them would have begun as an emergency and without…
Five days at ESC 2010, the world’s biggest international cardiology meeting -- with the Spotlight 2010 strongly focused on "Coronary Artery Disease: From Genes To Outcomes", but yes, so much more, too. This year’s programme is based on 4167 abstracts selected from more than 9,500 submissions, as well as over 120 Hotline and Clinical Trial Update presentations. From these, 35 Hotline sessions…
‘There are few reasons to deny a patient an MRI scan, and nearly all of them are having a pacemaker,’ said Pierre Bordachar MD at the Centre Hopitalière Universitaire (CHU), Bordeaux, France. Yet one-in-five pacemaker patients will require an MRI scan within the first year of receiving a pacemaker, while more than half of all pacemaker patients will need such a scan at some later point in…
According to data appeared on January, 26th, 2010 in JAMA (Journal of American Medical Association), patients with a common heart rhythm disorder, called Atrial Fibrillation, who were treated with catheter ablation* demonstrated significantly better outcomes at one year compared to those receiving drug therapy. In addition, the patients treated with catheter ablation reported markedly fewer…
Western societies are struggling to pay for their ever increasing medical budgets. In the US up to 393 billion US-$ were spent in 2005 for cardiovascular diseases alone. Based on epidemiologic studies in primary prevention it is reasonable to estimate that 30% of coronary heart disease and stroke could be prevented by 2.5 hours of brisk walking per week.
Echocardiography is the work horse of non-invasive cardiovascular diagnostics. Has this developed?
University of Utah researchers have found that delayed-enhancement magnetic resonance imaging (DE-MRI) holds promise for predicting treatment outcomes and measuring disease progression for patients with atrial fibrillation (AF), a little known heart rhythm disorder that affects more than 3.5 million Americans and causes more than 66,000 deaths a year. Their latest study on a novel application of…
In a symposium organised by Bayer Schering Pharma at the 2009 European Congress of Radiology (ECR), the audience heard a series of four presentations on the potential advantages of high-signal-intensity contrast agents for MRI, focusing on gadobutrol (Gadovist). During the discussion, several claims made by the speakers were challenged and debated by ECR delegates.
Royal Philips Electronics of the Netherlands and global company Bard Electrophysiology are starting a collaboration to develop new clinical tools for the work of electrophysiologists and lab staff. The ambitious goals are to improve the workflow with simpler and more intuitive approaches and to gain detailed visualization for interventions within the heart's electrical circuitry.
The common parlance knew it long before experts paid attention to it: a persons mood can be associated to its heart. But indeed in recent years much attention has been spend to depression following heart attack and its effects on prognosis. On the Congress of the European Society of Cardiology (ESC) two Dutch studies have been introduced indicating that especially somatic and incident depression…
Two Dutch studies indicate that especially somatic and incident depressions are associated with poor prognosis in cardiac patients, which is very different from the 'typical' psychiatric depression that is usually characterised by cognitive and recurrent depressive symtoms.
Royal Philips Electronics is to lead `euHeart´, the new European Union (EU) funded research project that aims to improve CVD diagnosis, therapy planning and treatment.
The diagnostic work-up of syncope patients often raises the question of how much diagnosis is necessary and what examination methods are really needed. To save time, specialists recommend focusing on determining whether the syncope may be caused by a cardiac problem - a question answered quite easily in many cases. Karl Eberius MD, European Hospital's new correspondent, discussed advice for…
Scanning the heart's arteries for calcium deposits might be one of the best ways to predict the overall risk of death for adults with cardiac trouble, a new study suggests. This might also help end the controversial discussions about calcium scans.
The Czech Republic's first cardiac transplant took place in 1984; now about 40 take place annually. The country's first lung transplants began ten years ago; to date around a hundred have been performed by Professor Pavel Pafko and colleagues at the Motol Faculty Hospital, in Prague.
Hall 16 While it is often possible to determine drug costs (or at least the defined daily dose) it is often impossible to determine actual costs of a particular case.
The European Commission (EC) has postponed the EU Directive that would have affected the use of MRI until 30 April 2012, to allow time for a substantive amendment to be adopted.
A joint project of more than 30 European stroke units just started to examine a potential connection between Fabry disease and stroke in young patients. The results of the worldwide SIFAP (Stroke in Young Fabry Patients) study might give an explanation for some of the 25% of strokes with unknown origin in patients aged 18-55 years.
During the annual meeting of the Society of Nuclear Medicine, in California this June, GE Healthcare announced the first installations of its new Discovery VCT - described as “the world's first true 64-slice combination positron emission tomography and volume computed tomography (PET/CT) system.”
25,000 visitors and medical professionals from 47 National Cardiac Societies across central and greater Europe, will attend the 2004 ESC Congress, where 'Diabetes and heart disease' will be the main theme. Lars Ryden, ESC Past-President, team member for the Euro-Heart Survey on Diabetes, and Chairman of the 'Guidelines for Diabetes & the Heart', and William Wijns, co-chair and Chairman of the…
