News • Tumor assessment via chromatin imaging
From DCIS to IDC: AI identifies breast cancer stages
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
As opportunities for teleoperations rapidly expand within radiology, the concept is being deployed across an array of modalities to deliver more efficient healthcare. A range of speakers covered the topic of ‘Teleoperations in radiology’ at ECR2024, discussing its benefits in applications in MRI, ultrasound, during the social restrictions of the Covid-19 pandemic and military use. However,…
New approaches to cardiovascular radiology are evolving to help clinicians gain an increasingly better insight into heart conditions. Latest developments in cardiovascular radiology include myocardial strain imaging, 4D flow and photon-counting CT technology. An ECR 2024 session shone the spotlight on these areas of cardiovascular imaging with expert speakers outlining the pros and cons of each.
The loss of myelin sheaths in the brain is a hallmark of multiple sclerosis. Swiss researchers have now developed an MRI method that maps the condition of this nerve insulation layer more accurately.
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
The underlying mechanisms of Guillain-Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.
A new soldering technique developed by Empa researchers is expected to prevent wound healing disorders and life-threatening complications from leaking sutures.
Cardiologists in Zurich demonstrate that immediate revascularization of non-involved blood vessels offers better outcomes for patients after a heart attack than a delayed procedure.
Machines are getting smarter every day, and companies across the world are discovering new ways in which they can use AI to significantly enhance engagement and customer experience. That is why decision-makers from pharmaceutical companies, hospitals and healthcare providers gather to network and discuss the latest innovations, as well as the potential for both AI and robotics, at Healthcare…
To ensure that wounds remain tightly sealed in the abdomen after surgery, researchers at Empa and ETH Zurich have developed a patch with a sensor function.
Photon-counting detector CT reduces the amount of contrast needed for CT angiography (CTA) while maintaining image quality, according to a new study published in Radiology: Cardiothoracic Imaging.
Swiss researchers developed a new MRI method to visualise metabolic processes in the body. Their objective is to improve the future diagnosis and treatment of heart disease.
The Red Cross is intended to protect aid workers from attack during their missions. Can this symbol also be used for the digital world – and what opportunities and risks are associated with it?
Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study examined how the treatment curbs the disease and how the immune system regenerates afterwards.
Driving the healthcare industry towards digital transformation was the main direction of Automa+ 2022. The Congress gathered leaders from hospitals and healthcare providers, pharmaceutical companies, governmental bodies and institutions as well as medical device manufacturers, service providers and start-ups in Zurich, Switzerland on September, 26-27, 2022.
Cancer immunotherapy is a successful treatment form in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers found.
Automa + Healthcare is held in September, and gathers leaders from hospitals & healthcare providers, governmental bodies and institutions with the goal to contribute to further development of ongoing digital health trends.
The research team Liver4Life has treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.
The impact of the coronavirus pandemic on lung cancer patient care across Europe, and the contribution lung pathologists, have led to a better understanding of Covid-19, as outlined during the 33rd European Congress of Pathology, Within ‘The lung pathologist in the Covid-19 pandemic’ session, speakers detailed how the pandemic has affected patients, diagnosis and clinical trials, yet also…
Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappeared completely, researchers at the University of Zurich (UZH) and University Hospital Zurich (USZ) have found. Their findings will now be tested in…
Researchers at ZHAW Zurich University of Applied Sciences are working with the Swiss company Osmotex AG to develop a self-disinfecting mask that inactivates viruses at the push of a button. The prototype of this mask made of electrochemical textiles shows an antiviral effect of over 99 percent. Further applications such as sterilizable seat covers are being examined.
To target ionised radiation as precisely as possible, imaging a tumour is vital in radiotherapy planning. ‘Today, imaging is used increasingly during the therapy itself,’ explained Professor Mark Ladd during the 51st annual meeting of the German Society for Medical Physics (DGMP).
Experts have identified two distinct immunological and cellular profiles in the lungs of Covid-19 patients which they believe could help define treatment pathways. From some of the earliest Covid-19 autopsies conducted in Europe, Swiss-based researchers have performed integrative digital pathology and transcriptomic analyses of lung tissues of 16 coronavirus patients who died from respiratory…
Bringing molecular and digital pathology closer together through a more integrative approach can lead to clear advantages for diagnostic and research workflows. During the recent Digital Pathology and AI Congress (London), Professor Viktor Koelzer explored the benefits and paid particular attention to colorectal cancer (CRC).
A team of researchers from Empa, ETH Zurich and Zurich University Hospital has succeeded in developing a novel sensor for detecting the new coronavirus. In future it could be used to measure the concentration of the virus in the environment - for example in places where there are many people or in hospital ventilation systems. Jing Wang and his team at Empa and ETH Zurich usually work on…
An international team of researchers from the University of Zurich, the University Hospital Zurich, Heidelberg and Glasgow has identified a novel function for the cell death regulating protein MCL1: It is essential in protecting the intestine against cancer development – independent of bacterial-driven inflammation. These findings have implications for the use of MCL1 inhibitors, currently…
Researchers at ETH Zurich and Inselspital, Bern University Hospital, have developed a method for predicting circulatory failure in patients in intensive care units (ICU) – enabling clinicians to intervene at an early stage. Their approach uses machine learning methods to evaluate an extensive body of patient data. Patients in a hospital’s ICU are kept under close observation: clinicians…
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week. This breakthrough may increase the number of available organs for transplantation, saving many lives of patients with severe liver diseases or cancer. Until now, livers could be stored…
Patients with the rare Loeys-Dietz syndrome suffer from aortic enlargement which may result in sudden over-expansion and a fatal aortic tear. In order to prevent this from happening, an aortic prosthesis must be implanted. A team of vascular surgeons at the University Hospital of Zurich was one of the first in the world to risk undertaking this life-saving operation on a child as an emergency…
In a symposium on September 9, 2019, the School for Translational Medicine and Biomedical Entrepreneurship (sitem-insel School) in Bern, Switzerland, provides an overview about current trends in artificial intelligence (AI) in medical imaging. From 8.30 to 17.00, participants in sitem-insel, Freiburgstraße, Bern will learn about the principles of AI as well as innovative applications in the…
Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma. A research team from University Hospital Zurich and the University of Oxford have now developed a method to predict the molecular classification of colorectal cancer from digital pathology slides.
Non-alcoholic fatty liver disease is among the most common chronic hepatic disorders in Western industrial countries and the rate is also rapidly rising in newly industrialized countries. Experts estimate that about 30 to 40 percent of the population worldwide develop this liver condition. In the United States, this disease is well on the way to becoming the most frequent indication for liver…
In intensive care units (ICU), some monitoring device or other is always sounding the alarm. Whether it’s a patient whose blood oxygen level is too low, someone in the next bed whose intracranial pressure is rising, or someone else whose blood pressure has taken a nosedive. Or perhaps just because a patient has shifted position in bed. False alarms like this last are all too common. They…
Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV. Researchers from the University of Zurich and the University Hospital Zurich have now shown that the genome of the HI virus is a decisive factor in determining which antibodies are formed.
‘Ultrasound plays a key role in diagnosis and monitoring of treatment in the A&E department,’ emphasises Professor Joseph Osterwalder, Medical Director of the Cantonal Hospital in Appenzell, Switzerland. ‘I cannot imagine emergency medicine without ultrasound.’
Just two decades ago, even though promising, point-of-care testing (POCT) was only used in hospitals and surgeries by a small number of specialists. Today POCT is in use throughout healthcare.
A Swiss hospital group is using drones to fly medical laboratory specimens between its key centres. In what is believed to be a world first, the eight-hospital Ticino EOC organisation has partnered with Swiss Post and US drone manufacturer Matternet to spearhead faster, more efficient specimens transport.
A controversy regarding the benefit of early screening programmes for breast cancer continues. Germany, Austria and Switzerland have developed individual strategies. European Hospital asked three experts from these countries to outline each chosen system. Markus Hahn MD, senior consultant at the University Breast Centre in Tübingen, Martin Daniaux, MD, Head of Breast Diagnostics at the Breast…
Celebrating 40 years of PCI, cardiologists fret over their future with big data, machine learning and robots.
Coronary angioplasty is arguably the most revolutionary breakthrough in the history of cardiology. While the technique is today performed on millions of patients worldwide, its origins can be traced back to Zurich, Switzerland, in the late 1970s.
Language recognition on the smartphone, spam filters in the e-mail programme, personalised product recommendations by Amazon or Netflix – all share one feature: they are based on an algorithm that recognises patterns in a set of data. This artificial generation of knowledge is called machine learning.
For the first time, researchers of the University of Zurich and Swiss Federal Institute of Technology in Zurich have demonstrated the causal context of why deep sleep is important to the learning efficiency of the human brain. They have developed a new, non-invasive method for modulating deep sleep in humans in a targeted region of the brain.
European Hospital reports a new approach in molecular diagnostics introduced during the IASLC World Conference in Vienna.
In rare cases, a dangerous bacterial infection occurs following major cardiac surgery. A device which is used for the regulation of body temperature has been found to be responsible for this. Since this discovery was made, Bern University Hospital has been working on guidelines for infection prevention.
Greater sensitivity and versatility of devices, as well as more patient-friendly implantation options, were issues outlined at the CardioStim 2016 EHRA Europace world congress on cardiac electrophysiology, held in Nice, France.
‘An autonomously working robot in the operating theatre will continue to be a vision of the future for a long time to come,’ according to Professor Uwe Spetzger, Clinical Director and Neurosurgery Specialist at Karlsruhe City Hospital. At the same time, he is calling for political support for the development and promotion of these innovative technologies and asking funding bodies to rethink…
The field is neither tedious nor monotonous; it’s fascinating every day, Professor Katharina Rentsch emphasises, when explaining the need to attract students to this often overlooked but intreguing and varied discipline.
Pathology is the gold standard of prostate diagnostics. Whilst the radiologist makes interpretations based on shadows and grey scale values visible on an image, the pathologist has the ‘fait accompli’ under the microscope. Professor Glen Kristiansen, Director at the Institute for Pathology at the University Hospital Bonn, explains why image-guided biopsies also make sense from the…
Radiotherapy always encounters particular challenges when a tumour is ‘mobile’. This is when radiotherapy must be carried out over several weeks. Within that period the tumour position, shape and expansion typically will keep changing. Thus radiotherapy needs continuous adaptation to maintain continuously precise radiation. Report: Chrissanthi Nikolakudi
'In paediatric cardiology, echocardiography is the method of choice for preoperative diagnostic purposes,' explains Professor Dr Emanuela Valsangiacomo-Büchel, senior cardiologist and director of cardiovascular imaging at the University Children’s Hospital Zurich, Switzerland. Report: Axel Viola
The number of radiological accident and emergency examinations had doubled within five years because many accident and emergency (A&E) patients are given CT scans even before having a comprehensive clinical examination. Report: Michael Krassnitzer
You are curious to know what this cardiac MRI thing is all about? You want to brush up on your cardiac MRI knowledge? Then we are afraid you have to delve into the technical basics. Sounds boring? It sure isn’t, says Dr Harald Quick.
Among new medical imaging innovations is a phase-contrast x-ray technique to bring greater precision to breast cancer assessment and improve biopsy diagnostics. EH asked research pioneer Professor Marco Stampanoni, a key figure in the development of this technique, to explain how it works. Report: Sascha Keutel
The ‘Fire of Life’ developed by Schiller is an intuitive visual presentation of frequency-domain heart rate variability (HRV) that makes the assessment of 24-hour results fast and simple.
Conflict and crisis situations pose specific challenges for medical care. The only way to cope with them is to apply scientific evidence from an exchange between academic surgeons and their colleagues active in the field. The EFORT Congress in London is a crucial hub at European level for this exchange.
European Hospital met up with Professor Harald H. Quick, PhD, who was appointed Director of the Erwin L. Hahn Institute (ELH) for Magnetic Resonance (MR) Imaging this February.
‘No large incision, no scalpel and no sutures: Radiologically guided, minimally invasive procedures can help many patients with chronic pain when conservative procedures don’t work,’ said Professor Siegfried Thurnher, head of the Department of Radiology and Nuclear Medicine at Vienna’s Hospital of St. John of God.
At the 99th Annual Meeting of the Radiological Society of North America (RSNA), two of Europe's leading radiologists were among the three recipients of the Honorary RSNA Membership Awards that recognize significant achievements in the field.
Neurologists keenly debate the value of mechanical reopening of blocked blood vessels in the brain, as demonstrated during the 21st World Congress for Neurology (WCN) in Vienna this September. Theoretically, endovascular thrombolysis can only be considered for 20-30% of all incidents of stroke.
Cooperation between the individual diagnostic fields of radiology, pathology and laboratory medicine has increased in daily clinical routine over the last few years. To a large extent, the three disciplines are faced with the same requirements and problems.
Experts from DEGUM, the German Society for Ultrasound in Medicine, are convinced that the use of ultrasound in preclinical and clinical emergency medicine can be further optimised, according to interim study results that indicate, in cases of unclear symptoms, the diagnosis and therefore decision for appropriate A&E treatment can be accelerated by using ultrasound.
Germany's hospitals are currently experiencing a construction boom: Whether its renovation, expansion or even new construction - the number of construction projects at German health care facilities is currently higher than at any time for 35 years with more than 1050 projects currently being implemented.
Petabytes of data on each patient will become the foundation of future diagnostics and therapy. Genetics, imaging and environmental information – toxins, lifestyle – will deliver a precise picture of the individual, allowing for diagnostic precision and targeted treatments.
Petabytes of data on each patient will become the foundation of future diagnostics and therapy.
In a market dominated by consolidations and falling prices, aiming to double turnover within three years requires either possession of the Philosopher’s Stone or extremely large amounts of creativity, entrepreneurial spirit and boldness. Diagnostics expert Unilabs, headquartered in Switzerland, belongs to the latter category.
They examine the structure of the heart muscle with magnetic resonance imaging (MRI) or evaluate the status of the coronary vessels with computed tomography (CT): radiologists increasingly use imaging methods to prevent or to assess cardiac diseases.
The fact that between 60% and 80% of people are expected experience some form of back pain at some point in their lives puts the importance of advances in imaging of the spine into context. A number of developments in imaging of the spine and peripheral nerves were outlined at a musculoskeletal scientific session at ECR 2012 in Vienna on Saturday morning.
The list of post-operative complications is long. Most common are fever, chest infection, pneumonia, wound infection, bleeding or deep vein thrombosis. As these post-surgical complications can range from minor, self-limiting problems to major life-threatening events, their definition and severity staging can be challenging.
Devices to treat chronic cardiac disease are winning credibility with new evidence from large-scale patient registries, John Brosky reports
An RFID transponder (also known as a tag) consists of a chip and tiny antenna. Thanks to their small size these transponders can be integrated into almost any object, including clothing, boxes or even sheets of paper. Thus the logistics industry numbers amongst the prolific areas of application for wireless frequency identification using RFID (radio frequency identification) technology.
How to finance the healthcare system? It’s an ongoing dilemma, particularly for in-patient care. According to a German Hospital Federation (DKG) estimate, the country’s hospitals currently suffer an investment backlog of €30-50 billion.
In hospitals, MRSA is considered Public Enemy Nr 1, and the increase in nosocomial infections, worldwide, has drawn universal attention to this ‘superbug’. However, Staphylococcus aureus is not alone – other pathogens are proving their resistance to antibiotics, in the last decade, gram-negative enterobacteria, which form the enzyme extended-spectrum beta-lactimases (ESBL), have joined the…
A special feature of this year’s scientific program at ECR 2010 was a joint session organized by the European Association for Nuclear Medicine with the European Society of Radiology. Two speakers representing the EANM took the podium to review developments in nuclear medicine and to challenge colleagues on specific applications.
The fast-expanding capabilities of imaging with computed tomography (CT) can leave your head spinning, which seemed to be the effect on the participants at the New Horizons Session at ECR 2010 entitled ‘Functional imaging in CT: Optional or built-in?’
Today testing of patients at the point of care (POC) accounts for 25% of all testing, and these portable assays are increasing their penetration into medical practice at rapid rate of 12% each year. Yet along with the growth comes an increasing risk of errors that adversely affect quality of clinical decision-making and patient safety.
At the European Society for Clinical Nutrition and Metabolism (ESPEN) congress in Vienna, experts highlighted the important relationship between nutrition and functionality in the elderly. They discussed the importance of an effective and flexible screening tool for the measurement of nutritional status, the impact of nutritional status on fall and fracture risk, and the role physical exercise…
The congress, held in tandem with this world famous medical fair, has traditionally been held in German. Now a new English language section is to be introduced to the Medica Congress 2009 programme. Speaking with Meike Lerner (EH), Dr Julia Rautenstrauch, Secretary General of Medica e.V. and head of congress, explained how the new concept will be integrated into the overall congress structure and…
Professor Wolfgang Heinrichs, of the AQAI Simulation Centre Mainz, Germany, notes that the 15th SESAM congress slogan "Europe-tradition and innovation in simulation", was born out by the choice of venue, the Mainz Simulation Centre was one of the first of its kind in Europe, and also hosted the 2000 SESAM congress.
Faced with death, what are the wishes of terminally ill patients? Does a request for euthanasia disappear with good palliative care? How invasive should medicine be at this final stage of life? Is comprehensive palliative care financially affordable? Can studies on those who are dying be ethically justified? Difficult questions, but all posed during the 11th European Association of Palliative…
The Magnetic Resonance Center of the University Children's Hospital Zurich has achieved a world first breakthrough in MR-guided, non-invasive neurosurgery. Ten patients have been successfully treated by means of transcranial high-intensity focused ultrasound. This fully non-invasive procedure opens new horizons for neurosurgery and the treatment of different neurological brain disorders.
“My dream is that children with neurological motion disorders will travel through virtual worlds with the help of a robotic gait orthosis. For example, they might explore a farm, smelling the country air and hearing the chickens cluck; while this is happening, the robot would provide them with physiological gait training”, said Professor Paolo Bonato, Director of the Motion Analysis…
IMRT is an evolving method of treatment for complex forms of cancer. Although patients benefit from treatment, a precise evaluation of that benefit and overall cost-effectiveness of the method is still an uncertain science. Mark Nicholls reports
Participation in the Hospital Manager Symposium, which is organized by EUROPEAN HOSPITAL in cooperation with the European Congress of Radiology and which is part of the congress, has increased continuously since its introduction six years ago. Last year about 250 attendees listened to the lectures and discussions.
The colder the weather, the greater the increase in blood pressure in the elderly population - to this conclusion comes a French study from Bordeaux, Dijon and Montpellier. The authors recommend to improve the blood pressure management in the elderly when outdoor temperature is very low by close monitoring of blood pressure and antihypertensive medication.
The Swiss charity EurAsia Heart, founded in 2006 by cardiac surgeon Professor Paul Vogt MD, at Zurich University Hospital, emerged from numerous contacts being made with Asian heart surgeons at the beginning of 2000, and consequent invitations to perform surgery and lecture tours in China.
The European multi-centre, multi-modality cardiac imaging project that could lead to a more intelligent and less costly use of today's technology in cardiac care.
According to a study conducted by researchers at the University of Zurich and the Zurich University Hospital the answer is: Yes. They demonstrated that one injection per month sufficed to improve blood sugar levels significantly. Even more: The insulin production of the patients improved.
Magnetic Resonance Guided Focused Ultrasound (MRgFUS) therapy was introduced in June at the Amperklinikum in Dachau, near Munich, the third German site, after Berlin and Bochum for this new technology.
For the first time in 33 years, wound healing was the focus of a dedicated session at the 33rd annual VEITHsymposium for vascular surgeons in New York (11/06). This underscores the fact that wound healing is heading increasingly towards a speciality that warrants the special attention of dedicated people willing to embrace an interdisciplinary approach to non-healing or complex wounds.
Slovakia was part of the Austrian-Hungarian Empire until 1918, when Czechs and Slovaks were brought together to form the Czechoslovak Republic. After World War II, and up to 1948, the country was still part of Europe, but then fell behind the 'Iron Curtain'. From 1989 it began 'knocking on the EU door' and entry was granted in 2003. Today Slovakia's population is around 5.38 million. To serve…
Fear for the quality of acute care for the injured and victims of accidents was expressed by Professor Vilmos Vécsei, traumatology and sports traumatology specialist and Head of the University Clinic for Trauma Surgery in Vienna (VV), as well as President and General Secretary of the European Trauma Society (ETS), and Professor Otmar Trentz, Director of the Trauma Surgery Clinic at University…
New pulsatile heart pumps (ventricular assist devices - VAD) can remain in the body as a permanent heart support.
Switzerland - Providing heroin addicts methadone or buprenorphine as a treatment for their addiction has led to a decline in the number of new heroin users in Zurich, according to a paper by Carlos Nordt and Rudolf Stohler from the Psychiatric University Hospital, Zurich, published in The Lancet.
Christopher Pryce, PhD, describes a promising test that can predict the onset of Alzheimer's disease some two years earlier than currently available tests can determine. Furthermore, the test can be used in non-human primates in order to research the neurobiology and pharmacology of such neurodegenerative illnesses. Dr. Pryce is conducting preclinical research with this test together with…