Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show a dramatic reduction in side effects, improving patient outcomes and quality of life.
Multiplex PET imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, according to scientists in Glasgow.
Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.
After pelvic radiotherapy, patients may live with low-grade chronic inflammation of the lower intestine 20 years after the treatment, a new study shows.
Cancer has become strikingly more common in people under 50 in the past three decades, an international research team finds. The reseachers explore what this means for future death tolls.
A mystery which has stumped bowel cancer researchers for decades, has been solved by scientists at the Cancer Research UK Beatson Institute and University of Glasgow.
A trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms.
Scientists from the University of Edinburgh have found that the accuracy of detecting bowel cancer is increased to almost 100% by carrying out a common test twice rather than once.
Patients with advanced ovarian cancer are now being recommended surgery that University of Birmingham researchers have found leads to better outcomes.
A new clinical trial has shown that men diagnosed with prostate cancer can benefit from ‘radical radiotherapy’ that delivers treatment in five hospital visits instead of the typical 20.
January 28 saw the celebration of the “Data Protection Day” as it is called in Europe, or respectively the “Privacy Day” as it is referred to outside of Europe. It marks the date on which the Council of Europe’s data protection convention, known as “Convention 108” was opened for signature back in 1981. According to the Council of Europe, it is the ‘only international,…
New tests can identify over 50 types of cancer and boost detection of traditionally elusive cancers from tumour DNA in blood, researchers showed at the ESMO congress in September. These multi-cancer early detection (MCED) tests in development can spot common cancer signals and predict where the signal comes from in the body, results from a prospective investigation suggest.
An advanced radiotherapy technique can be used to safely treat prostate cancer patients in as little as one to two weeks, compared with the current standard, which takes one to two months.
A new randomized study confirms that men with high-risk prostate cancer can be treated with a moderately shortened course (5 vs. 8 weeks) of radiation therapy.
Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models.
Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.
A randomized study shows colonoscopy screening reduces the risk of colorectal cancer by 18 percent. The reduction is much smaller than experts previously assumed.
Development of effective live bacterial therapeutics may depend more on using and re-introducing native microbes that can stick around than how the microbes are modified.
Hospital patients who develop infections where 10% of sufferers die will be offered double the traditional course of antibiotics in a new trial.
New research suggests that providing a break in treatment to patients with advanced bowel cancer could not only benefit a patient’s quality of life but could also help reduce costs.
More than 70% of patients with bowel cancer are not diagnosed using screening programmes meaning diagnoses are often made late, when the cancer is at an advanced stage, according to new research.
Surgeons completed the first documented ‘net zero’ operation in the NHS, combining evidence-based approaches and documents using a carbon output calculator developed specifically for this task.
The number of colorectal cancer (CRC) cases diagnosed fell dramatically by 40% in a year during the Covid-19 pandemic, new research presented at United European Gastroenterology (UEG) Week Virtual 2021 has shown. The research, which was conducted across multiple hospitals in Spain, compared data from the first year of the Covid-19 pandemic with data from the previous year. Of 1,385 cases of CRC…
A new technology that can study which therapies will work on patients with solid cancerous tumours has been developed by scientists at University College London (UCL). Researchers say the tool, which can rapidly test tumorous tissue against different treatments, such as chemotherapy, immunotherapy or radiotherapy, could be used by clinicians to pinpoint the best therapy for a particular patient.
Prostate cancer specialists from the Radiotherapy Department at Norfolk and Norwich University Hospitals Foundation Trust have become the first in the world to use an innovative technique to help patients receiving treatment for prostate cancer. Some patients receiving radiotherapy for prostate cancer will have their treatment split into two portions. The first stage of killing the cancerous…
Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms. In a paper published in the cancer journal Annals of Oncology, researchers report that the test accurately detected…
Statin use among patients with heart failure is associated with a 16% lower risk of developing cancer compared with non-statin users during an average of four years of follow-up. This is according to new research published in the European Heart Journal. In addition, the study found that statin use was associated with a 26% reduced risk of dying from cancer over the same period.
Specialist biorepositories are helping advance personalised medicine by supporting the availability of human tissue for research using digital pathology techniques. The pivotal role of the Glasgow Tissue Research Facility (GTRF) in making tissue available to shape new therapies and treatments was outlined in a presentation to the online “Transforming Digital Pathology – Integrating AI to Move…
The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (ASE) have joined the International Contrast Ultrasound Society (ICUS) in recognizing the relatively low risk and important clinical benefits of ultrasound contrast agents (UCAs), which are used routinely around the world to help detect heart disease, stratify the risk of heart attack or stroke,…
Bowel cancer survival rates could be improved if chemotherapy drugs were delivered via tiny nanoparticles to the diseased organs rather than oral treatment. That’s the finding from Indian and Australian scientists who have undertaken the first study, using nanoparticles to target bowel cancer, the third most common cancer in the world and the second most deadliest.
A test which uses artificial intelligence (AI) to measure proteins present in some patients with advanced bowel cancer could hold the key to more targeted treatment, according to new research. A team at the University of Leeds collaborated with researchers at Roche Diagnostics to develop the technique, which will help doctors and patients to decide on the best treatment options.
DNA errors in the cell’s energy ‘factories’ increases the chances of survival for people with bowel cancer, also known as colorectal cancer, according to a new study. Studying how DNA errors (mutations) can drive cancer development, as well as help it adapt and evolve, has been a key focus of cancer research. But much of that focus has been on DNA found in the cell’s nucleus. Experts say…
Miniature cameras which patients can swallow to get checked for cancer are being trialled across the NHS. The imaging technology, in a capsule no bigger than a pill, can provide a diagnosis within hours. Known as a colon capsule endoscopy, the cameras are the latest NHS innovation to help patients access cancer checks at home. Traditional endoscopies mean patients need to attend hospital and have…
Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. In the latest predictions for cancer deaths in the EU and UK for 2021, published in the cancer journal Annals of Oncology, researchers led by Carlo La Vecchia (MD), a professor…
Setting up ‘COVID-19 free’ hospital areas for surgical patients could save lives during the second wave of the pandemic – reducing the risk of death from lung infections associated with coronavirus, a new global study reveals. Researchers working together in Brazil and beyond found that that patients who had their operation and hospital care in ‘COVID-19 free’ areas had better outcomes.…
An AI (Artificial Intelligence) assisted polyp detector is helping endoscopists find more lesions during colorectal examinations. Leading endoscopists highlighted how the system is improving performance and finding flat or hidden polyps that the human eye could miss, in a webinar entitled “Artificial Intelligence - How to unleash the potential for colorectal polyp detection.” Hosted by the…
Smoking is strongly linked to lower use of cancer screening services by women, and more advanced disease once cancer is diagnosed, new research reveals. Tobacco use is falling in many parts of the world, but it’s falling less rapidly among women than it is among men. And lung cancer remains the leading cause of cancer death among women, say the researchers. The evidence also suggests that women…
Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.
Researchers have developed the first blood test that can accurately detect more than 50 types of cancer and identify in which tissue the cancer originated, often before there are any clinical signs or symptoms of the disease. In a paper published in the leading cancer journal Annals of Oncology, the researchers show that the test, which could eventually be used in national cancer screening…
Researchers from Karolinska Institutet, Örebro University and Aarhus University, Denmark, have published the largest study to date on the risk of colorectal cancer in Crohn's disease. The article is published in the journal The Lancet Gastroenterology Hepatology. Crohn's disease is a chronic inflammatory bowel disease (IBD). Several previous studies have reported an increased risk of colorectal…
The need to consider a formal recommendation on early screening for lung cancer was acknowledged by the Cross Party Group for Cancer, held at the Scottish Parliament in Edinburgh in January. Attended by over 40 people representing patients, the medical community, and the pharmaceutical industry as well as political advisers and Members of the Scottish Parliament, the Group agreed to write to the…
Computed tomography (CT) plays an increasingly important role in assessing pelvic disease, particularly when patients present with acute abdominal pain. In addition, radiomic approaches on CT are being developed to increase the characterisation of ovarian cancer for optimising treatment planning.
Diseases such as cardiovascular diseases, cancer or certain lung diseases are among the most common non-natural causes of death today and account for about 70 percent of deaths worldwide. They are defined by the World Health Organization (WHO) as non-communicable because they are assumed to be caused by a combination of genetic, lifestyle and environmental factors and cannot be transmitted…
Prostate cancer is the second cause of cancer-related death in men. Currently, its diagnosis occurs via imaging and must be confirmed by biopsy. Simona Turco from the Eindhoven University of Technology (TU/e) wants to improve prostate cancer diagnosis by using machine learning algorithms to localize tumors and thereby replace entirely the necessity for biopsies. Besides, by combining this with…
More than one in ten cancer patients do not die from their cancer but from heart and blood vessel problems instead, according to new research published in the European Heart Journal. For some cancers, like breast, prostate, endometrial, and thyroid cancer, around half will die from cardiovascular disease (CVD). Dr Nicholas Zaorsky, a radiation oncologist, and Dr Kathleen Sturgeon, an assistant…
Five talented robotics specialists were selected by an international jury for the finals of the Kuka innovation competition from among 30 applications from all over the world. For the first time, the focus was put on medical robotics and the topic of “Healthy Living”. Each of the finalists were provided with the sensitive Kuka lightweight robot LBR Med and a 3D vision system from Roboception…
Augsburg, Bavaria – Five teams of robotics specialists are finalists in the KUKA Innovation Award 2019 competition. Established in 2014, the Award focuses on medical robotics for the first time, Dr Rainer Bischoff, Vice President Corporate Research at KUKA, one of the judges of the award, explained. Around thirty talented robotics teams from all over the world submitted their concepts and an…
Chemical analysis of blood samples, combined with an artificial intelligence program, could speed up the diagnosis of brain tumours, according to research presented at the 2019 NCRI Cancer Conference. Brain tumours tend to have ambiguous symptoms, such as headache or memory problems, and a brain scan is currently the only reliable way of diagnosing them. Researchers say their test, which works by…
The results of a major study across 195 countries, presented at UEG Week Barcelona 2019, indicate that global death rates for pancreatic cancer and incidence rates for colorectal cancer both increased by 10% between 1990 and 2017. The Global Burden of Disease study, is the first to provide comprehensive worldwide estimates of the burden, epidemiological features and risk factors of a number of…
The World Health Organisation's (WHO) Essential Medicines List and List of Essential Diagnostics are core guidance documents that help countries prioritize critical health products that should be widely available and affordable throughout health systems. Now, updated versions of the two lists have been published, focusing on cancer and other global health challenges, with an emphasis on effective…
Cancers with the same genetic weaknesses respond differently to targeted drugs depending on the tumour type of the patient, new research reveals. The study is set to prompt changes in thinking around precision medicine—because it shows that the genetics of a patient's cancer may not always be enough to tell whether it will respond to a treatment. The researchers are already starting to design…
The pros and cons of CT (computed tomography), MRI (magnetic resonance imaging) and CEUS (contrast enhanced ultrasound) for emergency abdominal use were highlighted by speakers in an ECR 2019 session under the broader heading: ‘Abdominal Emergencies: advanced imaging in daily routine’.
Immuno-oncology is a therapy in which the body’s immune system treats a tumour. Dr Eric Borges, from the Research and Development Centre at Boehringer Ingelheim Pharma GmbH in Germany, explains why this is revolutionary. Unlike conventional cancer therapies, with immuno-oncology the tumour cell is not the direct target, it’s the patient’s immune system. The medication stimulates this to…
While the onset of inflammatory bowel disease (ulcerative colitis or Crohn’s disease) in adulthood is tied to a higher mortality, the actual number of deaths has been falling, a Swedish study from Karolinska Institutet published in the journal Gut reports. Now it is a case of ascertaining which of the newer treatments are the most efficacious, say the researchers. Using the Swedish National…
The rate of bowel cancer – also known as colorectal cancer or CRC – is rising among adults aged 20-49 in Europe, suggests new research. Rates rose most steeply among the youngest age group (20-29 years), and the authors warn that if the trend continues, screening guidelines may need to be reconsidered. Rates tend to be lower among people over 50, but the opposite is true among younger adults…
Cancer patients who undergo chemotherapy could soon benefit from a new AI that is able to identify and predict the development of different combinations of symptoms – helping to alleviate much of the distress caused by their occurrence and severity. In the first study of its kind, published by Nature Scientific Reports, researchers from the University of Surrey and the University of California…
The first report from a phase II, multi-center clinical trial indicates that a newer, more aggressive form of radiation therapy — stereotactic radiation — can extend long-term survival for some patients with stage-IV cancers while maintaining their quality of life. The study is published in the January issue of International Journal of Radiation Oncology • Biology • Physics (Red Journal),…
A pathology test that applies artificial intelligence (AI) to characterize tissue samples can accurately predict clinically significant prostate cancer disease progression following surgery, according to a study conducted at the Icahn School of Medicine at Mount Sinai.
Neuroscientist Lynda Chin MD, Founder and CEO of Real-world Education Detection and Intervention, has little doubt: ‘Artificial intelligence to the rescue,’ she proclaimed in her keynote address at the Artificial Intelligence and Machine Learning Summit, held in Las Vegas this spring. ‘We need a system and analytics to interpret data!’ she urged, despite being well aware that building a…
Obesity, cancers and other gastrointestinal diseases have digestive systems all over Europe in a chokehold. In a new report, non-profit organisation United European Gastroenterology (UEG) sheds a spotlight on the issues, challenges and inequalities of digestive health - and points out ways to fix the most pressing problems.
A far-reaching study conducted by scientists at Cincinnati Children’s reports that the Epstein-Barr virus (EBV)—best known for causing mononucleosis—also increases the risks for some people of developing seven other major diseases.
Testing cancer drugs on miniature replicas of a patient’s tumour could help doctors tell in advance which treatments will work, a major new study reports. The exciting new technique involves growing ‘mini tumours’ from biopsy samples – and could help end reliance on trial and error in selecting cancer treatments for patients where genetic tests are not predictive of response. Researchers…
Early detection of mesenteric ischemia increases treatment options and the possibility of a full recovery, but the condition’s rarity may lead to a delay in diagnosis while more common causes of abdominal pain are explored. An article in the February 2018 issue of Critical Care Nurse (CCN) aims to heighten nurses’ knowledge of mesenteric ischemia and infarction (MI), which are infrequent but…
Radiation therapy is a popular and effective treatment for many men with prostate cancer, and now a temporary gel offers greater protection for organs at risk during treatments. “Treating prostate cancer with radiation therapy can cause unintended injury to adjacent, healthy tissue, which can lead to bowel and urinary problems, as well as erectile dysfunction,” said Daniel Krauss, M.D., a…
A new genetic test to assess breast cancer risk in women who have a family history of the disease could be introduced into clinical practice in the UK within the next few months. Devised at Manchester University NHS Foundation Trust (MFT) and the University of Manchester, researchers believe the test for high-risk groups could also help reduce the number of women needing to have surgery to remove…
Nitzan Rosenfeld from Cancer Research UK in Cambridge is being honored with the 2017 Meyenburg Award, which carries a €50,000 monetary prize. He receives the award for his excellent work on the detection of tumor DNA in the blood. Rosenfeld has made seminal contributions to advancing a method for detecting cancer DNA in the blood to applicability in cancer medicine. The Meyenburg-Award will be…
Doctors have found that treating prostate cancer with a single, high dose of radiation delivered precisely to the site of the tumour results in good quality of life and fewer trips to the hospital, with adverse side effects that are no worse than if the radiation treatment had been given in several lower doses.
The Technion breathalyzer would give pathology groups and medical laboratories unprecedented ability to support physicians in diagnosing and treating cancers, chronic diseases, and other illnesses.
Pentax Medical EMEA announces its continued cooperation with SMART Medical to support the distribution and deployment of SMART’s G-EYE technology integrated with Pentax Medical’s HD+ systems to the EMEA market.
Professor Hans Clevers, researcher and group leader at the Hubrecht Institute in Utrecht, the Netherlands, invented the organoids, a ground-breaking new technique to grow new ‘organs’ and to test medication.
An international team of 56 researchers in five countries has confirmed a hypothesis first proposed by the ancient Greeks – that different diseases are characterized by different “chemical signatures” identifiable in breath samples. The findings by the team led by Professor Hossam Haick of the Technion-Israel Institute of Technology Department of Chemical Engineering and Russell Berrie…
Rectal cancer surgery - using a Da Vinci robot and conducted by Tas Qureshi, Consultant Surgeon and robotic lead at Poole Hospital NHS Foundation Trust - was beamed live from his operating theatre by satellite to an international conference of specialist doctors, student doctors and to a worldwide audience via multimedia platforms with live audio and twitter feedback.
Robot-assisted surgery still meets with considerable skepticism even though Intuitive Surgical’s Da Vinci system has been around for more than a decade. However, few surgeons and researchers are seeking ways to expand the surgical toolbox. Not so the members of the working group ‘Surgical technology and training’ at the General, Visceral and Transplantation Surgery Department, University…
A research team from the University of Liverpool has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.
Led by Professor Teoh Swee Hin, scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells. Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.
Around 25 treatments for seriously ill patients with specific cancers listed on England’s National Health Service’s Cancer Drug Fund are to be removed. This large change is likely to affect patients with cancers of the breast, bowel, prostate, blood, upper gastrointestine, brain and central nervous system, as well as gynaecological cases. Report: Mark Nicholls
A number of innovative research results were presented at the 24th Congress of the European Academy of Dermatology and Venereology that took place in Copenhagen from 7 to 11 October 2015. Some of these results are expected to impact medicine far beyond dermatology, demonstrating the innovative character of the specialty.
People have highly variable views on how much overdetection is acceptable in cancer screening, finds a UK survey. The authors say invitations for screening "should include clear information on the likelihood and consequences of overdetection to allow people to make an informed choice."
DNA Electronics (‘DNAe’), the inventors of semiconductor DNA sequencing technology and developers of a new point-of-need test for blood infections, highlights the urgent need for fast diagnostics to help tackle the growing threat of antibiotic resistance.
A first of its kind expert consensus report on Clostridium difficile infection (CDI), contributed to by more than 1,000 healthcare professionals across Europe, has been presented today at the Healthcare Infection Society (HIS) International Congress in Lyon, France. The consensus report aimed to identify a set of expert views on CDI management, in order to determine attitudes to diagnosis,…
For gastrointestinal exams, MRI fluoroscopy offers an alternative to conventional methods of swallowing and gastric emptying that are so repugnant to patients.
About 20 years ago the first tumour boards were set up in Germany. Initiated and led by surgeons, they not only invited oncologists, radiotherapists and radiologists to conferences but also, increasingly often, pathologists.
The NHS has to overcome people’s ‘status-quo bias’ if it is to increase the number of screenings for bowel cancer.
Dr Peter Choyke, Chief of the Molecular Imaging Programme at the National Cancer Institute in Bethesda, USA, believes that new tracers will have an evolving role to play and represent an exciting development in the imaging of cancers.
Along with a call for earlier identification and intervention in sepsis cases, intensive care consultant Dr Ron Daniels also stressed that timely intervention is cost-effective for health systems as it leads to fewer sepsis patients needing treatment in intensive care units (ICU).
Sahlgrenska University Hospital provides emergency and basic care for the 700,000 inhabitants of the Gothenburg region. It also provides highly specialised care for the 1.7 million inhabitants in Sweden’s west because, in this country, endoscopic ultrasound examinations are only provided in university hospitals. Thus Sahlgrenska’s physicians receive referrals of difficult diagnostic cases…
In 2006, about 307,432 new cases of colorectal cancer arose in the European Union. The rates varied by a factor of two for women and three for men. The lowest rates were in Greece; the highest in Hungary and the Czech Republic. The incidence of colorectal cancer is increasing in Europe, particularly in the south and east, where rates were originally lower than in Western Europe.
A small team of researchers at Barts and London School of Medicine and Dentistry, in London, has developed a rapid, cheap and effective kit to test for the presence of Clostridium difficile. And, they report that the new kit costs as little as 50 pence to £1 per test and can deliver results in under an hour, compared to commercial kits that cost up to £25 and in some cases take significantly…
Advanced endoscopes have already transformed certain surgical procedures. Thanks to minimally invasive surgery (MIS), such as NOTES (Natural Orifice Translumental Endoscopic Surgery), even bowel resection can be relatively scar-less. Such procedures are entering gastroenterology, as presented at the 40th Congress of the German Society of Endoscopy this March.
In 2000, the Israeli firm Given Imaging introduced Video Capsule Endoscopy (VCE), a new technology initially devoted to small bowel examination. Since then, the EndoCapsule from Olympus Japan, MiroCam from IntroMedic Korea and some less advanced devices from China have been introduced as technical competition for some new areas, such as oesophagus or colon.
Colorectal cancer is a suitable target for screening when it has a relatively high incidence – the second highest cancer incidence among women and third among men in Europe – and has a high mortality (~50% are expected to die of the disease), but can be cured if detected at an early stage.
Colorectal cancer occurs in approximately one in every 17 people during their lifetime and is the second leading cause of cancer death in Europe. Two new blood tests could aid in the early identification of patients with gastrointestinal (GI) cancers. The tests will make GI cancer detection simpler, cost-effective, and more acceptable to patients than current methods, the researchers say.
Colorectal cancer (CRC) jointly describes cancers of the colon and rectum. Worldwide, CRCs are among the most common cancers. In Europe and the USA the occurrence of CRCs are considerably higher than in Africa and Asia.
Incidence data from cancer registries have drawn the attention to colorectal cancer. It is one of the most common cancers in developed countries. In 2006, the estimated number of new cases in the European Union of 25 member states was 297,000 for both genders.
Founded and managed by Prof Peter Schlag, the Charité Comprehensive Cancer Centre (CCCC) co-ordinates cancer diagnostics and therapies across all medical disciplines. Interdisciplinary tumour boards decide on therapies/strategies; cooperation is close with general practitioners, regional hospitals and clinics.
To date, there is insufficient knowledge as to the cause of this disease, or how to prevent it. We asked some of our EH correspondents to report on measures taken in their countries to ensure that men are made more aware of this disease and whether screening services are provided for early prostate cancer detection.
Sonoelastography, a procedure that measures the elasticity of tissue and differentiates between healthy and hardened pathological tissue, will make cancer diagnosis safer in the future. For example, it has been shown to improve the accuracy of prostate cancer diagnosis by 20%.
Experts on a US panel expressed their doubts on the beneficial quality of prostate cancer screenings for elderly men. Prostate cancer often grows very slowly and may not kill an older man before he suffers from another death reason, they pointed out.
Brenda Marsh reports on the country's flourishing and expanding breast screening programme
Denmark - Regular drinkers significantly increase their risk of rectal cancer, but that risk is reduced if wine makes up a third or more of weekly consumption, according to research carried out by Professor Morten Grønbaek, at the Centre for Alcohol Research, National Institute of Public Health, Copenhagen, published in the journal GUT.
France - Less than 50% of those affected by bowel cancer survive beyond five years after diagnosis. However, new research* surprisingly suggests that a high calorie diet may increase chances of survival for longer.