New technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.
To ensure that wounds remain tightly sealed in the abdomen after surgery, researchers at Empa and ETH Zurich have developed a patch with a sensor function.
At the ESGE Days 2023 in Dublin, Pentax Medical has launched its newest products: the Inspira premium video processor, and the i20c video endoscope series.
Scientists at the University of Applied Sciences Krems (IMC Krems) show that CRISPR-Cas9 can also be used to inhibit viruses such as adenoviruses in cell cultures.
In a promising study, Canadian researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients.
A newly developed capsule that tunnels through mucus in the GI tract could be used to orally administer large protein drugs such as insulin.
Colonoscopies performed with AI support may yield an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27% in average-risk patients, according to new data.
Researchers from Tokyo Medical and Dental University (TMDU) develop a protocol to transplant 3D cellular structures that could regenerate damaged intestine.
Engineers at MIT have developed a kind of surgical duct tape — a strong, flexible, and biocompatible sticky patch that can be applied to biological tissues and organs to help seal tears and wounds.
The light from a smartphone screen can be used to print medications, in a new 3D printing technique developed by UCL researchers.
Virtual insights, telehealth devices portable imaging solutions and innovative approaches to endoscopy - at this year's Medica, Taiwanese companies again showcased their latest products. Even with a slightly reduced attendance due to the pandemic, the exhibitors found ingenious ways to promote their merchandise and attract the attention of potential business partners.
The number of colorectal cancer (CRC) cases diagnosed fell dramatically by 40% in a year during the Covid-19 pandemic, new research presented at United European Gastroenterology (UEG) Week Virtual 2021 has shown. The research, which was conducted across multiple hospitals in Spain, compared data from the first year of the Covid-19 pandemic with data from the previous year. Of 1,385 cases of CRC…
Researchers from the German Center for Infection Research (DZIF) at Charité – Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage. According to their report in Nature Communications, the researchers were able to identify four substances which inhibit SARS-CoV-2…
Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.
In many ways, our brain and our digestive tract are deeply connected. Feeling nervous may lead to physical pain in the stomach, while hunger signals from the gut make us feel irritable. Recent studies have even suggested that the bacteria living in our gut can influence some neurological diseases. Modeling these complex interactions in animals such as mice is difficult to do, because their…
Anorexia is a debilitating eating disorder, and was long thought to be purely psychological. New research is challenging this by revealing that gut microbes may have a significant role in anorexia. A recent review examines the evidence that gut microbes can contribute to anorexia and may provide a new method to treat it.
Researchers of the Technical University of Munich (TUM) have cultured so-called intestinal organoids from human intestinal tissue, which is a common byproduct when performing bowel surgery.
Bacteria and other microorganisms in the digestive tract are linked with dozens of health conditions including high blood pressure, high blood lipids, and body mass index (BMI) according to research presented at ESC Congress 2020. “Our study indicates that microbiota might have an important role in maintaining health and could help us develop novel treatments,” said study author Dr. Hilde…
Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.
In animals, a vaccine modifying the composition and function of the gut microbiota provides protection against the onset of chronic inflammatory bowel diseases and certain metabolic disorders, such as diabetes and obesity. This research was conducted by the team of Benoît Chassaing, Inserm researcher at Institut Cochin (Inserm/CNRS/Université de Paris), whose initial findings have been…
Dr Nicolas Azulay is a general medicine doctor specialising in scheduled and emergency ultrasound examinations at the University Hospitals of Nice, where he works at the Pasteur II and Cimiez hospitals. As part of the clinical research programme GERICARE, he recently studied the impact of point-of-care ultrasound (POCUS) assessment of patients admitted to the short-stay geriatric unit at Cimiez,…
All living creatures – from the simplest animal and plant organisms right up to the human body – are colonised by numerous microorganisms. They are thus in a functional relationship with these microbes, and together form a so-called metaorganism. The investigation of this symbiotic cooperation between host organism and microorganisms is a key challenge for modern life sciences research. The…
Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago. In carefully controlled experiments using germ-free mice populated with microbes from conventionally raised mice, the researchers showed that while the makeup of the microbial input largely determined the resulting…
Tiny particles that can fight cancer or that can easily pass through any interface within our body are a great promise for medicine. But there is little knowledge thus far about what exactly will happen to nanoparticles within our tissues and whether or not they can cause disease by themselves. Within an international research consortium, Empa scientists have now developed guidelines that should…
Targeting medical treatment to an ailing body part is a practice as old as medicine itself. A Band-Aid is placed on a skinned knee. Drops go into itchy eyes. A broken arm goes into a cast. But often what ails us is inside the body and is not so easy to reach. In such cases, a treatment like surgery or chemotherapy might be called for. A pair of researchers in Caltech's Division of Engineering and…
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body’s metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence. A research group led by Matteo Serino, Inserm researcher at the Digestive Health Research…
Engineers have developed a prototype endoscope which they say could cut the cost of manufacture from £80,000 to just £40. The redesigned device has the potential to revolutionise cancer screening in low-to-middle income countries where the cost of equipment makes screening prohibitively expensive. The endoscope is designed to see inside the upper part of the digestive tract for signs of…
Shahid Umar, PhD, researcher with The University of Kansas Cancer Center, has dedicated two decades of his scientific exploration to better grasp the connection between colon cancer and the human microbiome. Called the “forgotten organ,” the microbiome comprises trillions and trillions of microbes, including bacteria, fungi and viruses, in our body.
By studying fish raised in aquaculture, researchers from the Helmholtz Zentrum München, the University of Copenhagen and the University of Campinas in Brazil have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to the study published in the journal ‘Microbiome’, those mechanisms are more varied than previously thought. “In…
A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas of the body (metastases). The new findings are published ahead of print in the American Journal of Physiology—Gastrointestinal…
Obesity, cancers and other gastrointestinal diseases have digestive systems all over Europe in a chokehold. In a new report, non-profit organisation United European Gastroenterology (UEG) sheds a spotlight on the issues, challenges and inequalities of digestive health - and points out ways to fix the most pressing problems.
A recently identified pig virus can readily find its way into laboratory-cultured cells of people and other species, a discovery that raises concerns about the potential for outbreaks that threaten human and animal health. Researchers at The Ohio State University and Utrecht University in the Netherlands collaborated to better understand the new virus and its potential reach. Their study, the…
Hygiene is still a leading topic in endoscopy, and education remains crucial in Europe, according to Ulrike Beilenhoff, scientific secretary of the European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA). The two subjects took centre stage during the 21st ESGENA Conference, held during UEG Week in Barcelona this October. With around 600 participants, lectures, posters,…
21st century challenges are multitudinous for all. Ageing populations, a changing disease burden; increasing obesity with associated morbidities – Type 2 diabetes, cancer and cardiovascular disease; climate change pressures and more. Any new build plan demands a low carbon footprint; respect for the environment is paramount. To capture all those elements, the plan to regenerate a previously 10…
Columbia University Medical Center (CUMC) researchers have identified cells in the upper digestive tract that can give rise to Barrett’s esophagus, a precursor to esophageal cancer. The discovery of this “cell of origin” promises to accelerate the development of more precise screening tools and therapies for Barrett’s esophagus and esophageal adenocarcinoma, the fastest growing form of…
Over the next few years, in a research project funded by the EU, an international consortium is developing a new technology for a better treatment of multiple sclerosis. The idea of the innovative “Nose2Brain” approach is to transport a special active substance directly through the nose into the central nervous system.
Researchers at Cincinnati Children’s Hospital Medical Center grew functional stomach and intestinal tissues to study diseases and new drugs. They use pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes.
University of Limerick professor J Calvin Coffey has identified an emerging area of science having reclassified part of the digestive system as an organ.
Technological advances increasingly enable endoscopists to treat disease and perform surgical procedures. However, professionals must work hard to learn and maintain knowledge of complex interventions, says Dr Ferran González-Huix Lladó, President of the Spanish society of digestive endoscopy (SEED)
The increasing numbers of bacteria resistant to the newer generations of antibiotics is a public health problem on a global scale. Bacteria have an extraordinary capacity for adaptation, mutating permanently to overcome the action of our increasingly impotent antimicrobial armamentarium. A situation further aggravated by the use of the powerful ‘large spectrum’ antibiotics, creating further…
No one knows for sure how they got there. But the discovery that bacteria that normally live in the gut can be detected in the lungs of critically ill people and animals could mean a lot for intensive care patients.
With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Researchers at the University of Michigan Medical School have started to answer these questions by studying the microbiome of the lungs – the community of microscopic organisms that are…
The human body is inhabited by billions of symbiotic bacteria, carrying a diversity that is unique to each individual. The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. It is well established that a loss of bacterial symbionts promotes the development of allergies. Scientists at Helmholtz Zentrum Munich, at the Technical University of Munich…
‘Health insurers should keep a tighter rein on the quality of endoscopic interventions because, mostly, they represent a gentler alternative to surgery,’ asserts international expert Horst Neuhaus, during an EH interview. Report: Daniela Zimmermann/Juliane Dannert
Wrist-watches, wrist and arm bands, tags, finger rings, clips, smart glasses, shoes, insoles, smart patches (as thermometers), sensors woven into fabrics for T-shirts and socks and, of course, implantable devices as well as ingested pills were displayed by 23 exhibitors in the Wearable Technologies Show at Medica this year. Report: Cornelia Wels-Maug
At the close of the Gastrointestinal Medicine and Surgery meeting in Leipzig, Professor Peter R Galle, Congress President of the German Society for Gastroenterology, Digestive and Metabolic Diseases, spoke with EH about today’s emphasis on interdisciplinary exchange and the need to augment cooperation even further. Report: Chrissanthi Nikolakudi
The future will be aesthetic or, put another way, Art meets Science. With this motto, the 43rd Congress of the German Society for Endoscopy and Imaging Procedures e.V., jointly held in Munich with six other specialist associations, demonstrated that aesthetic means the brilliance of images generated by the latest generation of X-ray, CT, MRI and ultrasound equipment.
Major advances in Natural Orifice Transluminal Endoscopic Surgery (NOTES) lead to a tremendous interest in new surgical endoscopes. The advantages of minimally invasive surgery via natural body orifices, such as the mouth, are obvious: less post-operative pain, a minor infection rate, minor incisional hernia, shorter hospitalisation and, finally, better cosmetic results. Karoline Laarmann reports
World of Ultrasound met Prof. Ioan Sporea, Prof. Gebhard Mathis and Prof. Byung Ihn Choi to ask them three questions.
Morbid obesity is a chronic, lifelong, multifactorial, constitutional disease with negative medical, psychological, physical, social and economic side-effects. Obesity-related secondary diseases are Type 2 diabetes mellitus (T2DM), cardiovascular diseases such as hypertension or sleep apnoea. Report: Holger Zorn
Mechanical suturing tools are an indispensable part of modern surgery. Gastro-intestinal surgery as well as minimally invasive surgeries, would be unthinkable without this technology, a growing sub-market in an ever-growing industry, possibly driven by the patient’s benefit, writes Holger Zorn.
Endoscopy has advanced dramatically in the past decade with innovative technologies introduced by industry and novel procedures pioneered by physicians. Given a choice among the broad range of new tools, endoscopic surgeons simply want it all -- and are asking for more. During the Medica 2010 Congress, the Innovations in Endoscopy session rang with the word ‘combinations’.
Endoscopy has advanced dramatically in the past 10 years with innovative technologies introduced by industry and novel procedures pioneers by physicians. Given a choice among the broad range of new tools and techniques, endoscopic surgeons have decided they want it all. And they are asking for more.
Admittedly not one of the easiest names to pronounce but a name to note: Luhacovice in the Czech Republic.
Sonoelastography, a procedure that measures the elasticity of tissue and differentiates between healthy and hardened pathological tissue, will make cancer diagnosis safer in the future. For example, it has been shown to improve the accuracy of prostate cancer diagnosis by 20%.
Accurate diagnostic analysis and staging of cancer of the bile duct still remains a challenge. According to a new study from Germany a new imaging system called Cellvizio allows physicians to examine tissue at the cellular level from inside the body may now enable them to diagnose one of the most difficult cancers to detect.
French findings support the notion that gastric bypass can rapidly reverse diabetes symptoms' a side-effect that lap-band surgery does not show. The benefit results from a new-found element of glucose production by the intestine which also increases insulin sensitivity and lowers blood sugar.
Enzymes are biocatalysts that control the different metabolic processes of living organisms. These range from digestion to the copying of genetic information.
The World Health Organisation (WHO) quotes figures that indicate there are over one billion overweight adults spread across the world, as of 2007, with at least 300 million of these defined as clinically obese (as defined by a BMI (body mass index) of 30).
Wilhelm Niedergoeker, Managing Director of the Messe Dusseldorf GmbH, previews this year's events.