Findings from the largest UK study of patients hospitalised with Sars-CoV-2 infection show that long Covid leads to ongoing inflammation which can be detected in the blood.
Decreased rates of death and stroke: new research shows the validity of transcatheter aortic valve replacement in low-risk patients. This advocates a less invasive alternative to surgical options.
A recent suggestion to stop using the term ‘long-Covid’ may have been well-intentioned, but could ultimately do more harm than good, experts point out.
New approaches to cardiovascular radiology are evolving to help clinicians gain an increasingly better insight into heart conditions. Latest developments in cardiovascular radiology include myocardial strain imaging, 4D flow and photon-counting CT technology. An ECR 2024 session shone the spotlight on these areas of cardiovascular imaging with expert speakers outlining the pros and cons of each.
Using ultrasound imaging to detect Covid-19 infections, a new automated detection tool could help doctors in the emergency room diagnose patients quickly and accurately.
Patients who are suffering from aftereffects of a coronavirus infection often receive the diagnosis 'long Covid'. However, new research presented at ECCMID 2024 calls that term into question.
New study results explore the long-term effects of infection with Sars-CoV-2, and challenge the idea that vaccine immunity fades quickly.
Higher image quality, better spatial resolution: A new radiology study demonstrates how photon-counting CT imaging can improve evaluation of coronary artery disease.
How does a coronavirus infection cause neurological symptoms such as headaches, memory problems, and fatigue? A new study points to a different reason than previously assumed.
A new way to analyze blood samples for suspected sepsis gives doctors test results two days earlier than before – a head start that could mean life or death for patients.
During the Covid-19 pandemic, Switzerland relied on contact tracing to identify people likely to have been contaminated by an acquaintance. A research team assessed the effectiveness of this method.
Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.
An interplanetary title for a quite down-to-earth topic: The symposium "Men are from Mars, women are from Venus" at the EACVI congress (European Association of Cardiovascular imaging) launched into the differences between the hearts of men and women. While the speakers could firmly establish that both sexes share the same home world, variations in their cardiac anatomy warrant a more…
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
Researchers from the University of Southampton investigated how ultraviolet laser light destroys the coronavirus Sars-CoV-2 by impacting components critical for infection.
A new, large-scale study from Sweden underlines the importance of vaccination against Covid-19: The research shows that an infection raises the risk of heart rhythm disturbances.
Using diffusion MRI technology, researchers in Sweden have found differences in brain tissue structure between patients with persisting symptoms after Covid-19 and healthy people.
Being overweight – not just being obese – can increase Covid-19 severity. the elevated BMI creates an impaired antibody response to SARS-CoV-2 infection but not to vaccination, new research finds.
The Covid-19 pandemic has affected scientific research in numerous ways – for example by highlighting knowledge gaps in gender medicine. In many studies differences in morbidity and mortality between women and men surfaced incidentally. While the extent and causes of these differences remain largely unexplored, the preliminary insights confirm the need for further research.
Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…
Having coronary heart disease at a younger age was associated with an increased risk of dementia, Alzheimer’s disease and vascular dementia, a new study finds.
New research finds little evidence that post-surgical patient mortality is lower when patient and surgeon are the same gender.
A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.
A new study on public health communication shows that the term commonly used to describe bacteria resistant to current medicines or antibiotics fails to stick in people’s memories.
Researchers from Osaka University present a novel technique to detect different coronavirus variants quickly, including fast-spreading strains present in human saliva.
What does the future of the coronavirus look like? An international research team from Cologne and New York has developed a model to predict the likely evolution of Sars-CoV-2.
A new study shows five aspects of sleep that are almost equally important to explain the association between sleep and the risk of coronary events and stroke.
A new study found that the antibody response of infants and young children against Sars-CoV-2 deviates from that of adults in a small, but very significant way.
Stark inequalities in diagnosis and treatment of four of the most common heart conditions in the UK have been revealed in new research led by a team at the University of Leeds.
New research from Copenhagen University Hospital – Rigshospitalet and Herlev and Gentofte Hospital has shed new light on the immune system’s complex struggle against the coronavirus.
The enhanced infection safety measures installed for the Covid-19 pandemic also had a beneficial effect on hospital-acquired infections (HAIs) overall, a new US study suggests.
For their contributions to developing mRNA vaccines to fight Covid-19, Katalin Karikó, PhD, and Drew Weissman, MD, PhD, have been jointly awarded the 2023 Nobel Prize in Physiology or Medicine.
A new molecular test for bacteria and viruses, including Sars-CoV-2, has been developed at the University of Surrey, as they warn that the world needs to be prepared for the next pandemic.
Researchers from Rutgers University developed a way to help hospitals identify life-threatening Covid-19 cases using machine-learning software. The algorithm identified six crucial parameters.
A research team led by the Institute for Bioengineering of Catalonia (IBEC) and Hospital del Mar has conducted a study to analyze cough sounds recorded by smartphones in patients with Covid-19.
A team at Politecnico di Milano developed iHEART, a mathematical and computational model of the human heart designed for studying coronary artery disease.
From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.
Cardiologists in Zurich demonstrate that immediate revascularization of non-involved blood vessels offers better outcomes for patients after a heart attack than a delayed procedure.
Two new studies based on a large-scale cohort in Denmark explored the side effects of the coronavirus vaccine – one focused on acute effects, the other on a women's health issue.
Patients with immunodeficiency cannot benefit from conventional Covid-19 vaccines and still at risk from infection. A promising new approach now brings hope for this patient group.
Researchers from the University of Chicago developed a deep-learning model to assess chest X-ray radiographs for probable Covid-19 severity.
Researchers in France identified changes to the immune memory after infection with the Omicron BA.1 variant in thrice-vaccinated patients. The remodeling actually works to the patients' benefit.
A family physician at Tufts University School of Medicine offers advice for how to treat allergies and how to tell if symptoms are due to allergies, the common cold, the flu, or Covid-19.
While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.
A new device that combines microfluidics on paper, electrochemical transduction and immunoassays on magnetic nanoparticles is useful for easy and rapid diagnosis of lung diseases.
AI can use data from low-dose CT scans of the lungs to improve risk prediction for death from lung cancer, cardiovascular disease and other causes, a new study finds.
By using genetic data on multiple traits from people of non-European ancestry, scientists have improved the accuracy of polygenic scores in predicting disease risk for all.
Combining aerosol sampling and ultrasensitive biosensing, researchers have created a real-time monitor that can detect any of the Sars-CoV-2 virus variants in a room in about 5 minutes.
Do coronavirus vaccines skew the menstrual cycle, cause more bleeding or pain? Anecdotal reports hint at a connection. Now, a new study led by Boston University provides answers.
Research by the University of Southampton has shown that repeated Covid-19 vaccination increases the ability of lymphoma patients to prevent infection from the virus, particularly after four doses.
A new publication discusses deep-ultraviolet (DUV) photonics for the disinfection of Sars-CoV-2 and its variants (Delta and Omicron) in the cryogenic environment.
Surgical robots are becoming widespread in operating theatres, delivering accuracy and safety. An overview of the main systems, principal operators, the market and European initiatives in this field.
Photon-counting CT enables accurate diagnosis of coronary artery disease in high-risk patients, a potentially significant benefit for people previously ineligible for noninvasive screening.
An MRI invention from engineers at the University of Waterloo reveals better than many existing imaging technologies how Covid-19 can change the human brain.
Gentle cleansers are just as effective in killing viruses – including coronavirus – as harsh soaps, according to a new study from scientists at the University of Sheffield.
Results from a large European study reinforce the use of Extracorporeal photopheresis (ECP) in heart transplant patients as a treatment for heart transplant rejection and prevention of rejection.
Today, a large part of all further medical treatments is based on the results of laboratory analyses. The demand for complex test procedures remains high and the challenges for laboratories are growing.
Patients with heart disease could benefit from less extensive interventions thanks to technology that creates 3D computer models of blood flow through the heart's arteries, according to new research.
A study led by the National Institutes of Health’s RECOVER Initiative and supported by NYU Langone Health provides an expanded working definition of long Covid.
People with strong legs are less likely to develop heart failure after a heart attack, according to research presented at the Heart Failure 2023 scientific congress in Prague.
German researchers have now investigated whether there is a temporal association between infection with the Sars-CoV-2 virus and the development of type 1 diabetes.
Protection offered by Covid-19 vaccination declines more rapidly in people with severe obesity than in those with normal weight, scientists at the Universities of Cambridge and Edinburgh have found.
A study by investigators from the Mongan Institute at Massachusetts General Hospital shows serious effects in many aspects of the lives of health care workers due to the pandemic.
Getting vaccines to people who need them isn't always easy. Many vaccines require cold storage, making it difficult to ship them to remote areas that don't have the necessary infrastructure.
Messenger Ribonucleic Acid (mRNA) as a therapeutic approach is gaining momentum due to its ability to be rapidly manufactured and its promising outcomes.
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.
Among all but oldest age groups, the US has higher death rates than five high-income European nations, according to new UCLA research. However, this gap is only partly due to Covid-19.
US scientists report using a single-atom-thick nanomaterial to simultaneously detect Covid-19 and flu viruses — at much lower levels and much more quickly than conventional tests for either.
Predicting a Covid-19 infection from the sound of a cough? Researchers found that technology using Machine Learning performed no better than simply asking people to report their symptoms.
According to an accepted manuscript published in the American Journal of Roentgenology (AJR), using a dual-source CT (DSCT) scanner for coronary CTA can facilitate clinical processes by eliminating the need to administer beta-blockers for heart rate control while decreasing nondiagnostic examinations.
Researchers at the Universitat Autònoma de Barcelona (UAB) have developed a new type of nanoparticles inspired by the structure of amyloids, capable of neutralising the SARS-CoV-2 virus.
Arthroplasty for femoral neck fractures has seen enormous progress in recent years, but complications due to infections are still a major problem. With good preparation and the right technique, however, orthopaedic surgeons can take away much of the horror of this scenario.
True or false: Webcams have only recently been introduced in neonatology and are a patient-side component of the Digital Health Portfolio. False! Already in 1989, Professor Dr Roland Wauer at Charité Berlin built his DIY system to transmit images from the neonatology ward.
A new mathematical model developed by Hokkaido University engineers uses wastewater samples to effectively forecast the number of clinical Covid-19 cases in a community five days in advance.
Researchers developed a radiomics model that uses information from coronary CT angiography images to assess coronary plaque vulnerability, a common cause of heart attacks.
Researchers have developed an inhalable powder that could protect lungs and airways from invasion from the coronavirus or flu viruses by reinforcing the body’s own mucosal layer.
Nurses who worked in critical care during the Covid pandemic are at an increased risk of mental health problems, according to a new study.
Photon-counting detector CT reduces the amount of contrast needed for CT angiography (CTA) while maintaining image quality, according to a new study published in Radiology: Cardiothoracic Imaging.
The European Football Championship in 2021 had an impact on the participating countries' coronavirus infections, a new study shows. However, the extent depended greatly on the initial situation.
Artificial intelligence (AI) may help improve care for patients who show up at the hospital with acute chest pain, according to a new study published in Radiology.
A novel imaging agent can reduce the number of false-positive PET/CT findings among cancer patients recently vaccinated for Covid-19. This may mitigate the issue of tracer uptake in lymph nodes associaed with the vaccine.
After an infection with SARS-CoV-2, some people fail to recover their sense of smell. US researchers took a closer look at the olfactory nerve cells to find the reason for Covid-19-induced anosmia.
A newly developed rapid test needs only a few seconds to reliably detect pathogens such as SARS-CoV-2. It is based on specially designed magnetic nanoparticles.
A new study has found that antibodies produced in the nose decline nine months after Covid-19 infection, while antibodies found in the blood last at least a year.
Covid-19 vaccinations that combine two or more distinct variants of SARS-CoV-2 could offer protection against current and future ‘variants of concern’, say scientists from UK and Austria.
A new study demonstrates that AI models, using symptom and demographic features, can help predict Covid-19 infections, providing a way for rapid screening and cost-effective infection detection.
How does the coronavirus actually work? Dutch researchers have produced an animated video to visualise the life cycle of the virus using real-life microscopic images of infected cells.
In their pursuit of solutions for pandemic challenges, a US hospital system applied telemedicine principles to respiratory therapy – with impressive results.
Researchers tracked viruses passing through face masks and compared their failure on the filter layers of different mask types. This could accelerate the development of surfaces that can kill viruses.
Researchers have developed a so-called “heart attack on a chip”, which could one day serve as a testbed to develop new heart drugs and even personalized medicines.
A promising new application for photon-counting CT: The new technology outperforms conventional CT in detecting subtle damage in the lungs of patients with persistent symptoms of Covid-19.
Adults with asthma had, at one point, an approximately doubled risk of a severe asthma attack after Covid-19 restrictions were relaxed in the UK, according to new research.
Eunsin Bae, M.D. specializes in laboratory medicine and leads the Institute of Clinical Research at Seegene Inc. Her research focuses on microbiology, molecular biology, and hematology. Dr. Bae is currently working toward implementing a global clinical study and establishing an international network of clinical investigations.
Innovative gastrointestinal imaging, medical panel PCs with hygiene optimisation, smartphone-based diagnostic tools, and sustainable hardware setups: At Medica 2022, manufacturers from Taiwan again showed their capability to adapt and provide solutions for a world radically changed by the Covid-19 pandemic. Under the “Taiwan Excellence” banner, outstanding products from the island nation’s…
Using a special type of MRI, researchers have uncovered brain changes in patients up to six months after they recovered from Covid-19, according to a study being presented at the annual RSNA meeting.
During the Covid-19 pandemic, the use of these single-use diagnostics, or point-of-care tests has exploded. This is having major environmental consequences, experts point out.
There is no evidence of higher risk of miscarriage or ectopic pregnancy following vaccination against Covid-19 or infection with the disease, according to a new study.
Innovative smart weighing scales are adding a new dimension to home monitoring for healthcare. By collecting data via sensors and proprietary technology as people stand on them, the scales can assess health metrics to give users more precise measurements for a deeper understanding of their body.
At this year's Medica tradefair, laboratory medicine, medical technology and life sciences give new impulses to the entire healthcare market - especially in times of the corona pandemic. An overview.
A new X-ray technology has been used to identify a link between the damage that severe Covid-19 can inflict on lungs and pulmonary fibrosis, a disease that causes severe scarring of lung tissue.
Until now, it was feared that vaccination against Covid-19 could reduce the success of treatment for patients with nasopharyngeal cancer. A recent study now gives the all-clear in this regard.
Speed or accuracy? As far as Covid-19 tests go, this was the choice you had to make. In the future, this dilemma could be a thing of the past.
Donor hearts from people who were Covid-19-positive appear to be as safe for transplantation as those from people without Covid-19, according to a new short-term analysis.
The Pluslife Mini Dock System is a Next-Generation POC molecular diagnostic tool that can be used in different application scenarios, which aims to help the decentralization of MDx in diagnosing facilities.
Despite treatment, chronic lung diseases such as COPD or cystic fibrosis can become so severe that a lung transplant is necessary. Dr Urte Sommerwerck explains which patients might be considered for transplantation and why follow-up is as important as the surgery itself.
The coronavirus pandemic caused by SARS-CoV-2 and its variants is still a major public safety issue worldwide. The “alpha” variant B.1.1.7, the “gamma” variant P.1, the “beta” variant B.1.351, and the “delta” variant B.1.617 are of particular concern because of their high prevalence. Large-scale vaccination and sensitive detection are vital for preventing the spread of Covid-19.
The coronavirus pandemic is a huge challenge for global public health and welfare. Decentralized, affordable POC MDx platforms would allow more effective control of SARS-CoV-2 and other infections.
Research presented in a new preprint suggests that SARS-CoV-2 might have been artificially created in a laboratory. Experts from Würzburg have reviewed the paper – and remain unconvinced.
A vaccine design approach that could protect against new variants of SARS-CoV-2 but also potentially protects against other coronaviruses is one step closer to reality as a result of new research.
A new study finds that virtual care during the Covid-19 pandemic led to a significant reduction in CO2 emissions and patient travel-related expenses, such as gasoline, parking or public transit costs.
Methamphetamines, cocaine, opiates, and cannabis are associated with an increased likelihood of developing atrial fibrillation, a newly-published 11-year study shows.
Covid-19 has led to global mortality changes unprecedented in the last 70 years, according to new research. However, the drop in life expectancy is not equally high in all countries.
A study in Japan finds antibody response to the Moderna Covid-19 mRNA vaccine does not vary depending on the time of day when the dose was received.
Referrals to Cambridge’s long Covid clinic fell dramatically in the period August 2021 to June 2022, which researchers say is likely due to the successful rollout of the vaccine.
Researchers have shown that when brain cells are directly exposed to blood taken from Covid-19 patients with delirium, there is an increase in cell death and a decrease in the generation of new brain cells.
It’s widely known that more than 70% of today’s medical decisions involve the results of laboratory tests, but the insights clinicians derive from these tests today may only be scratching the surface of their potential.
Recent advances in CT have focused mainly on software, yet new technology could push the modality much further, experts showed at ECR 2022.
A research group has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.
What will the next pandemic look like? Health officials from across the globe gathered in Geneva in late August at a World Health Organization meeting to focus on how lessons learned from Covid-19 might best prepare civilization for the "next one."
How can rapid antigen tests be adjusted to reliably detect future variants of SARS-CoV-2? A research team funded by the National Institutes of Health is currently working on finding an answer.
An international team of researchers advises that strong care needs to be taken not to misuse or overuse machine learning (ML) in healthcare research, despite all of its benefits.
The hearts of men and women are different – while this insight has been established for quite some time now, it might even surprise cardiologists just how deep these differences really run. In her presentation at this year’s ESC, Diana Bonderman, MD, gave a comprehensive roundup on sex differences in risk factors and subtypes of heart failure.
A new system capable of reading lips with remarkable accuracy even when speakers are wearing face masks could help create a new generation of hearing aids.
An important prospective study showcases improvement in outcomes for women with ischemic heart disease by attending a multidisciplinary women’s health center.
Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.
Artificial intelligence (AI) can be used to detect COVID-19 infection in people’s voices by means of a mobile phone app, according to research to be presented at the European Respiratory Society International Congress.
Vaccination projects across the world are at a pivotal post-Covid moment, according to one of the leading experts in the field. Speaking to Healthcare in Europe ahead of the World Innovation Summit for Health (WISH) congress in Qatar – where vaccination will be a central topic – Dr Jerome Kim said there is an urgent need to regain a ‘positive consensus’ around the value of vaccines. He…
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
Danish smokers bought less tobacco and more quit smoking during the Covid pandemic, new research finds. This comes as a surprise given that mental health and exercise habits waned during the lockdown.
The critical times in a woman’s life of pregnancy and the menopause – and their relation to heart health – is explored at the ESC. The defined field of gender-specific cardiology is becoming an increasingly important area of focus, experts say.
It might sound like science fiction but it is reality in cardiology: with the help of artificial intelligence (AI) physicians can recognize from a patient’s headshot whether the person is suffering from coronary artery disease and is therefore at risk of myocardial infarction. But is that knowledge really useful? Professor Dr David Duncker calls for a differentiated and careful assessment of…
The overall risk of myocarditis is substantially higher immediately after being infected with Covid-19 than it is in the weeks following vaccination for the coronavirus, a large new study shows.
New diagnoses of disorders including psychosis, dementia, seizures and ‘brain fog’ remain commoner two years after Covid-19 than after other respiratory infections, new research finds.
The combination of deep-learning reconstruction and a subtraction technique yields promising diagnostic performance for the detection of in-stent restenosis by coronary CTA.
The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.
At the ECR 2022 congress in Vienna, Hologic went beyond just showcasing new systems for women’s health. Additional focus topics were the mitigation of the pandemic impact on screening programmes and the situation of women around the world without access to advanced diagnostic technologies – or even the most basic standards of healthcare.
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
More than 225,000 tweets with the hashtags #scamdemic and #plandemic led to an “infodemic” of misinformation and disinformation on Twitter during the first year of the pandemic, a new study finds.
Avian flu, MERS, Covid-19, monkeypox: outbreaks of infectious diseases are getting more common in Europe. As a result, the EU must adapt its surveillance strategies and introduce more data-driven, interdisciplinary countermeasues.
Researchers propose a new Covid-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies - a promising alternative for people with a weakened immune system.
Long Covid sufferers have experienced a wider set of symptoms than previously thought including hair loss and sexual dysfunction, new research has found.
As knowledge about Covid-19 advances, so does the arsenal of techniques to predict, diagnose and follow up on the disease. At ECR, researchers presented a range of promising imaging modalities to keep track of Covid-19 symptoms, severity, and mortality, often including AI support to enhance or accelerate diagnostics.
Researchers have developed a new Covid-19 test distribution method that uses drones to quickly deliver at-home diagnostic tests to individuals who suspect they have Covid-19.
A sprayable coating that can prevent the surface spread of infection from bacteria and viruses – including Covid-19 – over a sustained period has been developed by Australian researchers.
Leading radiologists have debated whether working from home is a blessing or a curse amid the evolving impact of teleradiology. In a hybrid ECR session examining working from home in radiology, speakers discussed their own experiences.
Skin swabs are "surprisingly effective" at identifying Covid-19 infection, according to new research, offering a route to a non-invasive future for Covid-19 testing.
The Covid-19 pandemic has highlighted the importance of the fast and accurate diagnosis of infectious diseases in clinical settings. Harald Maier discusses the implementation of rapid molecular diagnostics in the central clinical diagnostics laboratory at Innklinikum Altötting and Mühldorf, highlighting how the use of PCR testing has benefitted the hospital during the Covid-19 pandemic.
Researchers have been able to produce antibodies to the SARS-CoV-2 spike protein in hen eggs. Antibodies harvested from eggs might be used to treat Covid-19 or as a preventative measure.
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from Geneva reveals the exceptional capacity of Omicron to evade our immunity.
A new type of vaccine provides protection against a variety of SARS-like betacoronaviruses, including SARS-CoV-2 variants, in mice and monkeys, according to a new study.
Using functional MRI with inhaled xenon gas, researchers have identified that long COVID symptoms are related to microscopic abnormalities that affect how oxygen is exchanged from the lungs to the red blood cells.
Staff across all levels of UK health and social care reported feeling betrayed, morally violated and being treated unjustly and unfairly at work during the Covid-19 pandemic.
Russia's war against Ukraine is also playing out in cyberspace. In the process, clinics in Germany could also be caught in the digital crossfire, IT experts warn.
Recovery from severe Covid-19 is characterized by a reduction of certain white blood cells and changes in the molecular regulation of the immune system, an international research team found.
Handheld, instrument-free test delivers lab-quality molecular results – 97.9% accuracy – in about 15 minutes, right at the point of care.
Over the past years, the world has been transforming into a post-Covid era. Taiwan has stepped up to the challenge on innovation and taking the advancement of digital healthcare to a whole new level.
A research group from Kyoto developed two in vitro models to study SARS-CoV-2, and showed that they can be used for drug screening for infectious diseases including Covid-19.
COVID-19 pandemic has caused “global collateral damage” by disrupting cardiac services . Across the world problems with heart health will “...continue to accrue unless mitigation strategies are speedily implemented”.
When a virus makes its way into the body, one of the immune system’s first responders is a set of pathogen-removal cells called macrophages. But they don’t all target viruses in the same way.
A special type of MRI found lung abnormalities in patients who had previously had COVID-19, even those who had not been hospitalized with the illness.
Researchers have developed a novel way to fabricate diagnostic devices using paper-based microfluidics that can be rapidly prototyped and scaled for manufacturing.
In patients with serious and long-term Covid-19, disturbed blood coagulation is often observed. Now, Swedish researchers found a connection between harmful amyloid production and Covid-19 symptoms.
SARS-CoV-2 depends on the broadly antiviral interferon-induced human transmembrane proteins , to enter human cells and replicate inside them.
Two years after infection with COVID-19, half of patients who were admitted to hospitals still have at least one symptom, according to the longest follow-up study to date.
UV radiation is one of the go-to methods for preventing the spread of SARS-CoV-2. But what UV dosage kills the virus? What wavelength? How long? A new study answers many of those questions.
In 2020 and 2021, the death toll associated with Covid-19 was approximately 14.9 million, according to the World Health Organization. However, the global distribution has been far from equal.
Personalised screening, data-driven aproaches: In a dedicated press conference in Paris, French oncologists presented promising research that might bring hope for many cancer patients.
Cognitive impairment as a result of severe Covid-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, scientists found.
A method for delivering genetic material to the body that has proven useful in Covid-19 vaccination is now being tested as a way to repair damaged heart muscle after a heart attack.
Six in ten people with Covid-19 still have at least one symptom a year later, a new study has found. Furthermore, symptoms that don’t clear up after 15 weeks are likely to last at least a year.
Using mass spectrometry and chromatography techniques, UK researchers have developed an approach to predict infection severity among Covid-19 patients, as well as potential outcomes.
A global analysis of nearly 6 million Covid-19 deaths finds an increase in mortality at weekends compared to weekdays. Bureaucratic and reporting delays alone do not explain this, researchers report.
By comparing the infectious viral load caused by ancestral SARS-CoV-2 as well as by the Delta and Omicron variants, scientists highlight the benefits of vaccination.
A new study enables developers to determine vaccine safety via smart sensors that measure objective physiological parameters. This could end the reliance on subjective reports of study participants.
Sleep problems could hint at a heightened risk of heart disease, caution experts at the ESC Preventive Cardiology 2022 congress.
The COVID-19 testing device can detect coronavirus infection in as little as 30 seconds as sensitively and accurately as a PCR test.
Point-of-care testing (POCT) is a “win-win” scenario for patients and healthcare professionals in delivering care when and where it is needed, according to pathologist Adil Khan, MSc, PhD.
Hygienic, single-use components are widely used in endoscopy to ensure patient safety but are considered wasteful. Reprocessing is a more sustainable alternative but requires special equipment and training to avoid equipment contamination. This creates an area of conflict for physicians, hospital staff, but also for manufacturers. We spoke with two experts at Pentax Medical about challenges in…
Researchers are developing wearable devices to catch early signs and symptoms of diseases or monitor sick patients. We spoke to wearables and medical device expert Professor John Rogers about the benefits, challenges, trends and innovation within the sector.
SARS-CoV-2 has heavily impacted global society with high pressure on public health and economics. MolGen is proud to assist in relieving some of the pressure and support the testing framework.
Contrast agents in the wastewater and power-hungry imaging systems: The eco-footprint of healthcare is huge, and radiology departments are among the main culprits. An expert panel at the ECR Overture explored ways to make the field “greener”.
Researchers have found another long-term complication associated with Covid-19 infections: peripheral neuropathy during and following their bouts with the virus.
To provide a solution for the challenges of the coronavirus pandemic, Beckman Coulter recently launched the DxU Iris, a urinalysis solution which aims to improve lab workflows.
A significant number of Covid-19 neurological complications – such as fatigue, headache, and cognitive impairment – are ultimately reversible, according to new research.
People who were bedridden for at least a week due to Covid-19 are more likely to experience anxiety and depression for up to 16 months after the infection, a new study shows.
The MD-Bio BCC19 Coronavirus test utilizes RT-LAMP technology to provide accurate results in just 30 minutes.
The new 3D-printable mask design promises easy breathing for users while maintaining similar levels of protection against pathogens found in N95 and surgical masks.
Combining questions about a person's health with data from smartwatch sensors, a new app can predict within minutes whether someone is infected with COVID-19.
COVID-19 measures such as school closures and ‘high-traffic and mixing’ areas had the strongest association, providing clues for new intervention approaches.
A new study has analyzed over 3000 proteins to identify which are causally linked to the development of severe Covid-19. This provides insight into potential new targets for treatment and prevention.
When it comes to imaging stable cardiac chest pain, which modality should be used as the first-line test to investigate coronary artery disease: CT or MRI? Radiologists discussed the strengths and limitations of the two approaches in a lively Pros and Cons session at ECR Overture.
Traces of the SARS-CoV-2 coronavirus that causes COVID-19 can be detected in microscopically small fluid droplets exhaled during a very short time span.
The tool has made it possible to detect SARS-CoV-2 in exudate from symptomatic patients with a sensitivity of 100% and a specificity of 87.5%
The Covid pandemic might be responsible for a “substantial decrease” in mental wellbeing in the UK, according to new research from the University of East Anglia and University of York.
A new UK review shows that people who have had one or more doses of a coronavirus vaccine are less likely to develop long Covid than those who remain unvaccinated.
Cardiac rehabilitation can be done just as well at home as in the hospital. This is the conclusion of the most extensive research into ‘tele-rehabilitation’ to date.
Is the Underground a safe means of transport in times of Covid-19? A computer simulation, developed at the University of Leeds, has calculated the infection risk.
Scientists have confirmed that an inhaled form of COVID vaccine can provide broad, long-lasting protection against the original strain of SARS-CoV-2 and variants of concern.
Researchers have developed an inexpensive, non-toxic coating for almost any fabric that decreases the infectivity of the virus that causes COVID-19 by up to 90 per cent.
Researchers have developed a noninvasive and reagent-free technique for the efficient detection of COVID-19.
Professor Richard Neher from the Biozentrum of the University of Basel is using his Nextstrain platform to investigate which variants of the SARS-CoV-2 virus are currently circulating worldwide.
Researchers from Charité – Universitätsmedizin Berlin and Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) present new findings on the immune response against SARS-CoV-2.
A new study shows that the SARS-CoV-2 Omicron variant is less effective than Delta at blocking a cellular defence mechanism against viruses, the so-called 'interferon response'.
How long can Covid-19 antigen tests reliably tell the antibody status? Researchers at the Paul-Ehrlich-Institut identified several factors that affect the detection duration.
A passive air sampler clip can help assess personal exposure to SARS-CoV-2, which could be especially helpful for workers in high-risk settings.
Researchers have developed a diagnostic for SARS-CoV-2 that is capable of differentiating between COVID-19 and the garden-variety bug with fast turnaround.
The COVID-19 pandemic has led to deficiencies and large inequalities in the care of mothers and newborns in Europe.
New study results show that though men are more likely to have heart conditions, the impact on their memory and thinking skills is lower.
The long-term impact of the coronavirus pandemic on antimicrobial resistance remains difficult to predict. Infectious diseases consultant Professor Alison Holmes reflects on Covid-19's effect on antibiotic use in hospitals and beyond.
Interventional cardiology is entering a new era with the wider introduction of robotic procedures which bring significant benefits to the medical team and the patient. Two experts outlined the benefits at the ESC 2021 Digital Summit.
Scientists at have designed a quantum sensor to detect SARS-CoV-2 faster, cheaper, and more accurate than the current gold-standard technique, PCR.
Ever since the Abbe diffraction limit of conventional microscopy has been surpassed, super-resolution techniques have been diving ever deeper into the most miniscule details of molecular structures. We spoke with Prof. Dominic Zerulla, whose company PEARlabs is developing an imaging technique that sets out to push the boundaries once more – by looking at in-vivo nano-scale processes in motion.
The Coronavirus SARS-CoV-2 infects the kidneys and contributes to tissue scarring, as shown by researchers from Germany and the Netherlands.
An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants.
Using a new x-ray imaging approach, an interdisciplinary research team has detected significant changes in the heart muscle tissue of people who died from Covid-19.
The Omicron variant of SARS-CoV-2 may be significantly better at evading vaccine-induced antibodies – but preliminary evidence suggests it is less likely to cause severe illness in the lungs.
An invisible protective wall of UV-C light developed by researchers in Munich could reliably curb the spread of viruses and other pathogens in rooms while allowing total freedom of movement.
A worldwide consortium aims to equip researchers in low- and middle-income countries (LMICs) with cheap and accessible methods for sequencing large collections of bacterial pathogens.
Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…
Researchers in the UK and China have developed an AI model that can diagnose Covid-19 as well as a panel of professional radiologists, while preserving the privacy of patient data.
Radiologists in Paris have developed a standardised simple visual lung damage CT severity score for Covid-19 patients who do not have symptoms of severe acute respiratory syndrome (SARS) at the time of initial treatment.
Doctors in Lisbon report on the case of a 61-year-old man who received a double lung transplant after his lungs were irreparably damaged by Covid-19.
When the coronavirus first struck in the US, hospitals in New York City were the first to feel the impact. Radiologists Professor Judy Yee, M.D., and Mark C. Liszewski, M.D., describe the lessons learned and talk about their firsthand experiences.
A large-scale qualitative study looks into the difficulties frontline doctors faced across two waves of the Covid-19 pandemic in the UK and Ireland since early 2020.
Safety trials are underway for a Cambridge-led vaccine that could be used as a booster targeting Covid-19 virus variants and relatives that threaten future coronavirus pandemics.
A novel artificial intelligence score provides a more accurate forecast of the likelihood of patients with suspected or known coronary artery disease dying within 10 years than established scores used by health professionals worldwide. The research was presented at EuroEcho 2021, a scientific congress of the European Society of Cardiology (ESC).
Founded in 2018 as a DNA extraction chemistry company, Dutch company MolGen entered the market operating within the agricultural sector. At first, the company’s founders, Maarten de Groot, Wim van Haeringen and Niels Kruize, focused solely on this one industry, mainly developing and marketing advanced bulk chemistry kits for DNA/RNA extraction. These testing products and solutions successfully…
In experiments using saliva samples from COVID-19 patients, the gum, which contains the ACE2 protein, neutralized the virus.
A new strategy to reduce the spread of COVID-19 employs a mobile robot that detects people in crowds who are not observing social-distancing rules, navigates to them, and encourages them to move apart.
Test could measure patient immunity against multiple COVID-19 variants such as Omicron and Delta at once and inform which synthetic monoclonal antibody to use for treatments.
Since its introduction around 60 years ago, the screening of newborn babies for immune, hormone and metabolic disorders has prevented many people from experiencing severe disease progression. The scope of systematic early testing has been significantly enhanced through mass spectrometry (MS). In our interview, Professor Uta Ceglarek, one of the driving forces behind the introduction of MS…
After the four-day run, organisers of Medica and Compamed express their satisfaction with the results of the events in Düsseldorf. From 15 to 18 November 2021, the world’s leading information and communication platforms for the medical technology industry and its supplier sector presented a wealth of convincing innovations as well as an accompanying programme that covered a wide range of…
Compared to previous SARS and MERS, SARS-CoV-2 became a pandemic due to the high infectivity and different mode of contagion. SARS-CoV-2 spreads more because it is contagious also before symptoms, during incubation phase. No tests to date have been able to find the virus during the pre-symptomatic stage. Stark has developed a new, rapid, non-invasive method "Stark Portable Covid-19 Antigen…
Some ten years ago, it was unthinkable that virtually all company data was stored in the cloud. Now it’s what almost every company does. However, the increasing complexity of corporate IT infrastructures also comes at a price. The sheer size and complexity of the systems makes it difficult to keep track of everything that is going on digitally. And this leads to more and more successful…
X-ray vision, context-sensitive guidance, coordinator, training assistant and more: augmented reality (AR) has hit the OR. While still in its infancy AR does grow rapidly and has already shown enormous potential. University Professor Dr Rüdiger von Eisenhart-Rothe, Chair of Orthopaedics and Sports Orthopaedics at the Technical University Munich, explains the advantages of different AR…
Since Compamed could only be held digitally last year, due to the pandemic, the event now takes place publicly again. Almost 500 registrations from exhibitors prove that there is a high level of interest from medical technology suppliers – a huge step towards reaching normality again.
The Corona pandemic has a major impact on all areas of life. Nearly everyone is affected in some way – in their health, in their jobs, in their entire lives. But there are also notable bright spots. Chief among these effects is the rapid development of vaccines, test kits and, in the future, medicines that are making a significant contribution to overcoming the crisis. Microfluidic components…
Video streaming of surgeries, augmented reality displays and at-home assessment of sleep apnea: Medtech companies from Taiwan will showcase their newest products at Medica in Düsseldorf. Ahead of the trade fair, the Taiwan External Trade Development Council (TAITRA) presented award-winning examples of the nation’s ingenuity.
"Virtual Care & Digital Therapeutics", "Medical Artificial Intelligence & Robotics", "Fields of Innovation" and "Societal aspects of digitized healthcare" are the topics of this year's Health IT Forum at Medica. New this year: In line with the hybrid event concept of the trade fair, the Expert Panels, Tech Talks and Deep Dive Sessions can be…
The damage caused by Covid-19 to the lungs’ smallest blood vessels has been intricately captured using high-energy X-rays emitted by a special type of particle accelerator. Scientists used a new imaging technology called Hierarchical Phase-Contrast Tomography (HiP-CT), to scan donated human organs, including lungs from a Covid-19 donor.
There has been a "positive shift" in inclusive gender practices in Covid-19 vaccine research, but there is still room for improvement, experts say. Women have been equally recruited and represented in randomised control trial research about Covid-19 vaccine safety, efficacy and effectiveness, according to a new study by The George Institute for Global Health and The Australian National…
A study by the Universities of Basel and Saarland shows that there is almost no risk of transmission of the Covid-19 virus on the field. They suggest that blanket quarantine measures for opposing teams are not justified if no close contact has taken place off the playing field. Governments have introduced various measures over the past 18 months in an effort to curb transmission of the Covid-19…
French researchers have found that addressing concerns related to the Covid-19 vaccination via a chatbot interface might be capable of swaying the vaccine-hesitant. Vaccine hesitancy is one of the major challenges in containing the Covid-19 pandemic. Previous studies have revealed that mass communication—through short messages relayed by television or radio—is not a very effective means of…
At their workplace, neurosurgeons often have to make compromises since most ORs were not designed with the specific needs of their discipline in mind. To address this issue the University Hospital in Essen, Germany, equipped an OR especially for neuro- and spine surgery. The aim is nothing less than revolutionizing the field with the help of digitalisation and cutting-edge technology.
Researchers at the Catharina Heart and Vascular Center, together with Eindhoven University of Technology, have developed a new measurement method to analyze the smallest capillaries of the heart by measuring blood flow and resistance. The new method to assess coronary microcirculation allows cardiologists to make a clearer diagnosis. Until recently, the tests used for this purpose were not…
“Twindemic” is a term that has not yet been in the headlines but is likely to become part of our lexicon as the summer progresses.
Scientists at Lausanne University Hospital (CHUV) and École polytechnique fédérale de Lausanne (EPFL) have discovered a highly potent monoclonal antibody that targets the SARS-CoV-2 spike protein and is effective at neutralizing all variants of concern identified to date, including the delta variant. Their findings are published in the journal Cell Reports.
A new rapid molecular diagnostic test from Cepheid has received the CE mark for distribution in the European market. The test, called Xpert Xpress CoV-2/Flu/RSV plus, is designed for qualitative detection of the viruses causing Covid-19, Flu A, Flu B, and respiratory syncytial virus (RSV) infections from a single patient sample. The new plus version of the test provides a third gene target for…
The Covid-19 crisis that gripped England between September 2020 and June 2021 can be thought of as a series of overlapping epidemics, rather than a single event, say researchers at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and the German Cancer Research Center.
Making recommendations for change, academics analyzed global data into the prevalence of antimicrobial resistance in urban areas—the rise of which is threatening the lifesaving role of the medications.
Hope for a future without fear of Covid-19 comes down to circulating antibodies and memory B cells. Unlike circulating antibodies, which peak soon after vaccination or infection only to fade a few months later, memory B cells can stick around to prevent severe disease for decades. And they evolve over time, learning to produce successively more potent “memory antibodies” that are better at…
After infection with SARS-CoV-2, where does the immune system store the memory to provide long-term protection against reinfection? Though numerous studies have examined blood to track immune responses to SARS-CoV-2, a new study of Covid survivors shows that the memory of the infection is primarily stored in T and B cells within the lung and the lymph nodes surrounding the lung.
Water, hygiene and infection prevention solutions and services provider Ecolab launches its Hand Hygiene Compliance Measurement (HHCM) System, a digitally connected technology to systematically monitor and improve hand hygiene in healthcare settings, across Europe. In healthcare settings, clean hands save lives. While the Covid-19 outbreak increased adoption of hand hygiene measures at first,…
The impact of the coronavirus pandemic on lung cancer patient care across Europe, and the contribution lung pathologists, have led to a better understanding of Covid-19, as outlined during the 33rd European Congress of Pathology, Within ‘The lung pathologist in the Covid-19 pandemic’ session, speakers detailed how the pandemic has affected patients, diagnosis and clinical trials, yet also…
The number of colorectal cancer (CRC) cases diagnosed fell dramatically by 40% in a year during the Covid-19 pandemic, new research presented at United European Gastroenterology (UEG) Week Virtual 2021 has shown. The research, which was conducted across multiple hospitals in Spain, compared data from the first year of the Covid-19 pandemic with data from the previous year. Of 1,385 cases of CRC…
A new series of protocols for treating patients with the most severe types of hearts attacks can reduce deaths by more than 50%, and eliminate gender disparities in care and outcomes, according to a new study by Cleveland Clinic.
Medical technology startup EpiGuard has received the 2021 Oslo Innovation Award. Presented during the first day of the of Oslo Innovation Week, the Scandinavian city’s annual technology festival, Ellen Cathrine Andersen, CEO of EpiGuard, collected the award from Vegar Andersen, advisor for the City of Oslo’s Vice Mayor for Business Development and Public Ownership.
A study found that women who contract Covid-19 during pregnancy are at significantly higher risk of developing pre-eclampsia. In their study, researchers said their systematic review shows that women with SARS-CoV-2 infection during pregnancy had 62% higher odds of developing preeclampsia than those without the infection during pregnancy.
A treatment combining two antibodies is recommended for two specific groups of patients with Covid-19 by a WHO Guideline Development Group panel of international experts and patients.
Long COVID symptoms rarely persisted beyond 12 weeks in children and adolescents unlike adults.
Study suggests need for better ventilation and tight-fitting masks, in addition to widespread vaccination to help stop spread of the virus.
According to new research, vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death from 14 days post the second dose vaccination, when substantial immunity should be expected.
Thousands of unvaccinated French health workers face suspension without pay under a new COVID-19 law that punishes people in care professions who refuse to get immunised against the virus.
The role of Artificial Intelligence (AI) is one of the most divisive issues in cardiology. Two leading experts argue the pros and cons of its use, exploring its benefits and advantages to cardiac care, as well as highlighting the pitfalls and shortcomings of AI, while underlining the need for clear guidelines and regulations for its use going forward.
Hospitalized Covid-19 patients are substantially more likely to harbor autoantibodies — antibodies directed at their own tissues or at substances their immune cells secrete into the blood — than people without Covid-19, according to a new study.
Colourful, 3D rendered scientific images are fascinating - but can they deceive viewers? New research from Spain suggests this might be the case. According to the study by the Instituto de Radio Televisión Española and the Universitat Autònoma de Barcelona conducted during the Covid-19 lockdown, black and white images of SARS-CoV-2 make the virus seem more infectious. The results, published on…
To better prepare and protect the world from global disease threats, H.E. German Federal Chancellor Dr Angela Merkel and Dr Tedros Adhanom Ghebreyesus, World Health Organization (WHO) Director-General, have inaugurated the new WHO Hub for Pandemic and Epidemic Intelligence, based in Berlin.
Covid-19 infection does not appear to affect the lung function of young adults, according to new research presented at the ‘virtual’ European Respiratory Society International Congress. In the first study to investigate the impact of Covid-19 infection on lung function, researchers led by Dr Ida Mogensen, a post-doctoral fellow at the Karolinska Institute, Stockholm, Sweden, found that even…
Researchers in Thailand have developed a device to get the most out of vaccine supplies: The automated vaccine filling machine from the Faculty of Engineering at Chulalongkorn University can fill AstraZeneca vaccine into syringes with precision, speed, and safety, helping to increase the number of vaccinated people by 20 percent. The prototype is now operating at Chula Vaccination Center and more…
Adults who have received a double vaccination are 49% less likely to have Long Covid should they contract a Covid-19 infection, according to new research from King's College London. The scientists analysed data from participants logging their symptoms, tests and vaccines on the UK ZOE COVID Symptom Study app between 8th December 2020 and 4 July 2021, including 1,240,009 (first dose) and 971,504…
Delegates at an international radiography conference were given an insight into the impact Covid-19 has had on their profession and practice in five countries across the world. A special session at the online ISRRT (International Society of Radiographers and Radiological Technologists) congress in Dublin (August 20-22) heard experiences from Thailand, Nigeria, Italy, India and Ireland, with…
The World Health Organization (WHO) has taken a closer look at coronavirus variant B.1.621. The strain, first encountered in January 2021 in Colombia, shows traits that could enable the virus to circumvent immune response to vaccination. As a result, the variant, named "Mu", has been classified as "Variant of Interest" (VOI). Despite its prominence in Colombian new infection,…
Unsupervised deep learning breaks new ground by predicting the progression of COVID-19 and survival of patients directly from their chest CT images.
Combining imaging modalities is helping to achieve better diagnostic and therapeutic outcomes for heart patients. The topic, discussed in detail by experts at the ICNC-CT online International Conference on Nuclear Cardiology and Cardiac CT, examined hybrid/fusion imaging as the standard in cardiovascular imaging, and its value in clinical practice. Professor Terrence Ruddy spoke about the role of…
Researchers from the University of Oxford have announced the results of a study into thrombocytopenia (a condition with low platelet counts) and thromboembolic events (blood clots) following vaccination for Covid-19, some of the same events which have led to restricted use of the Oxford-AstraZeneca vaccine in a number of countries.
An AI-led device to assess coronary CT angiographs has been designed to assess cardiac plaque that may lead to myocardial infarction (MI). In his presentation ‘Vascular inflammation and cardiovascular risk assessment using coronary CT angiography’ (CCTA), Charambalos Antoniades, Professor of Cardiovascular Medicine at the University of Oxford, presented the research team’s findings during…
Coronary computed tomography angiography (CCTA) is a non-invasive imaging test which can be used to evaluate coronary artery stenosis and measure plaques. Current plaque analysis is time-consuming and needs expert readers in order to help assess a patient’s heart attack risk. That’s about to change.
Until recently, TAVI, the minimally invasive procedure in which a replacement valve is inserted inside a diseased valve has been mostly prescribed for patients too weak to face open heart surgery – largely involving those in the 80-plus age group. Today, due to greater longevity plus advancing skills that result in risks reduction, TAVI is increasingly prescribed for patients in their 70s and…
Artificial Intelligence (AI) is providing numerous opportunities across clinical care in the field of cardiovascular imaging. While challenges remain, AI is being applied in terms of diagnosis and prognosis, defining cardiovascular imaging pathways, and image acquisition and analysis. It can also help cardiologists predict which patients may do well, or which treatments are best applied to those…
Alongside the worldwide increase in longevity, inevitably with chronic health conditions rising, cardiovascular procedures and OR utilisation have surged. Thus the efficient and safe performance of surgeries is even more important. The intraoperative use of mobile C-arms increases accuracy, improving clinical outcomes, which can significantly reduce revision rates and thus overall healthcare…
People who work night shifts are at increased risk of developing an irregular and often abnormally fast heart rhythm called atrial fibrillation (AF), according to research published in the European Heart Journal. The study is the first to investigate the links between night shift work and AF. Using information from 283,657 people in the UK Biobank database, researchers found that the longer and…
Scientists have grown beating heart cells to attempt to identify drugs to prevent Covid-19-related heart damage. Concerns over the extent of cardiac damage among Covid patients emerged during the coronavirus pandemic and there are also suggestions that the impact on cardiomyocytes could contribute to the symptoms of long Covid. To explore these issues, a research team at the University of…
Each wave of the pandemic has underscored just how contagious Covid-19 is, but there is less clarity among experts on exactly when—and to what extent—infected individuals are most likely to spread the virus.
Obtaining two vaccine doses remains the most effective way to ensure protection against the Covid-19 Delta variant of concern dominant in the UK today, according to a study from the University of Oxford. Conducted in partnership with the Office of National Statistics (ONS) and the Department for Health and Social Care (DHSC), the study found that with Delta, Pfizer-BioNTech and Oxford-AstraZeneca…
New research from the University of Oxford and the UK Centre for Ecology & Hydrology uses mathematical modelling to determine the most equitable way to share vaccines between nations. Vaccines provide a route to achieving high levels of immunity against SARS-CoV-2 across populations, and provide a route to reopening economies, tourism, and livelihoods. However, vaccine resources amongst…
A new study of patients with cerebral venous thrombosis (CVT) following Covid-19 vaccination provides a clearer guide for clinicians trying to diagnose and treat patients. The research, led by University College London (UCL) and UCL Health and published in The Lancet, is the most detailed account of the characteristics of CVT, when it is caused by the novel condition vaccine-induced immune…
Covid-19 disease severity is determined by the individual patient’s immune response. The precise mechanisms taking place inside the lungs and blood during the early phase of the disease, however, remain unclear. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität Berlin have now studied the cellular mechanisms…
Researchers identify two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants. The team, spearheaded by researchers at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – may have found the “Achilles’ heel” of the virus, with potential for pan-variant therapeutic interventions. The findings are now published in the EMBO…
Some people change the narrative about technology and society. One of them is Nuria Oliver, Chief Data Scientist at Data-Pop Alliance, Chief Scientific Advisor at the Vodafone Institute, and Co-founder and Vice-president of the European Laboratory for Learning and Intelligent Systems (ELLIS). In an interview with HiE, she explains how she develops computational tools and uses artificial…
A research team led by scientists in the labs of Jennifer Doudna, David Savage and Patrick Hsu at the University of California, Berkeley, is aiming to develop a rapid Covid-19 diagnostic test that is much faster and easier to deploy than qRT-PCR. It has now combined two different types of CRISPR enzymes to create an assay that can detect small amounts of viral RNA in less than an hour. Doudna…
Microwave engineers, infectious disease specialists and polymer scientists from the University of Edinburgh, Heriot-Watt University and the University of Strathclyde have teamed up to create a novel microwave sterilisation method that could revolutionise the way ambulances and hospitals are being disinfected.
Italy, France, and Greece have made Covid-19 vaccination mandatory for healthcare workers, and England is making it compulsory for care home workers and consulting on whether to extend this to healthcare workers and other social care staff. Experts debate in The BMJ whether frontline health and social care workers should be compelled to take up the vaccine, if efforts to encourage them fail.…
Israel’s first virtual hospital has been created following the advances and applications learned from using telemedicine tools and techniques to care for coronavirus patients in isolation wards. Sheba Beyond was established in January and over the last few months has successfully delivered care to patients across a range of areas. The development of the project was outlined to the DMEA –…
A novel study published in AACC’s The Journal of Applied Laboratory Medicine shows that delaying the second Covid-19 vaccine dose for more than the recommended 3-4 weeks results in higher antibody levels. This finding could play a vital role in shaping vaccine distribution strategies that increase access to the vaccine around the globe.
How long do coronaviruses remain infectious on banknotes and coins? Is it possible to become infected through contact with cash? Experts at the European Central Bank, in collaboration with the Department of Medical and Molecular Virology at Ruhr-Universität Bochum, wanted to clarify this question. The researchers led by Professor Eike Steinmann and Dr. Daniel Todt developed a method specifically…
Home test kits to check for Covid-19 spike proteins and anti-Covid-19 antibodies are fast and simple to use but lack the sensitivity and accuracy of laboratory tests. Researchers from Eindhoven University of Technology with Utrecht University have developed a new type of sensor that combines the sensitivity and accuracy of current laboratory-based measurements with the speed and low-cost of…
In view of the continuing high numbers of infections, vaccination offers important protection against severe Covid-19 disease. Scientists from the Faculty of Medicine – University of Freiburg have now been able to determine in detail at what time point initial immune protection is established after vaccination with an mRNA-based vaccine and how the reactions of the various components of the…
Patients who experience long Covid have reported more than 200 symptoms across 10 organ systems, in the largest international study of ‘long-haulers’ to date, led by scientists at University College London together with a patient-led research collaborative.
Markers in our blood – ‘fingerprints’ of infection – could help identify individuals who have been infected by SARS-CoV-2, the coronavirus that causes Covid-19, several months after infection even if the individual had only mild symptoms or showed no symptoms at all, say Cambridge researchers. The team has received funding from the National Institute for Health Research to develop a test…
David Johnson, Global Director Commercial Excellence at ADVANZ PHARMA, explains the value of off-patent medicines to hospitals and healthcare systems, as the repercussions of the Covid-19 pandemic are still having a significant impact on resources.
The Lausanne University Hospital (CHUV) and EPFL teamed up to develop a new test that’s sensitive enough to measure the amount of SARS-CoV-2 neutralizing antibodies present in the bloodstream. The scientists’ discovery, published in Science Translational Medicine, opens promising new avenues for tracking immunity acquired by infection or vaccination.
To date, there are no effective antidotes against most virus infections. An interdisciplinary research team at the Technical University of Munich (TUM) has now developed a new approach: they engulf and neutralize viruses with nano-capsules tailored from genetic material using the DNA origami method. The strategy has already been tested against hepatitis and adeno-associated viruses in cell…
Artificial intelligence (AI) could match the impact of PACS on radiology. Covid-19 stimulated the development and testing of AI diagnostic-aiding tools in radiology, an unintended consequence of the pandemic. More image data sets have been created to train AI software – an unexpected benefit for radiology research.
Life science research and clinical diagnostics company Bio-Rad Laboratories announced the launch of its PREvalence ddPCR SARS-CoV-2 Wastewater Quantification Kit, a tool to detect the virus that causes Covid-19 in a community’s wastewater. "With wastewater testing becoming more widely adopted, this assay provides the ability for a community to determine if the virus is present days to…
The net benefit of vaccinating children is unclear, and vulnerable people worldwide should be prioritised instead, say experts in The BMJ today. But others argue that Covid-19 vaccines have been approved for some children and that children should not be disadvantaged because of policy choices that impede global vaccination.
Although the coronavirus affects men and women differently, the vast majority of clinical trials do not mention sex/gender, a new analysis of 4,420 studies concludes. Ultimately, it can influence the treatment negatively. The meta analysis is published in Nature Communications. According to the new research, only 4 percent of 4,420 registered studies explicitly plan to address sex and gender in…
Medical robotics company Robocath and Rennes University Hospital announce the launch of a co-development research program using robotics to improve treatment for stroke victims. With the support of Philips France, this program will be implemented over the next four years. It will focus on the use of robotics in treating strokes, the second most common cause of death globally after myocardial…
SpeeDx Pty, Ltd. and MolGen announced the signing of an agreement to collaborate on supply and distribution of clinical diagnostics products and instrumentation across Europe and Asia Pacific. The partnership links specimen handling, nucleic acid extraction, assay set-up, amplification, and results reporting in a seamless integration of the companies technologies. “This partnership capitalises…
A study by Newcastle University, University of East Anglia and charity Fifth Sense, shows poor levels of understanding and care from GPs and specialists about smell and taste loss in patients. This is an issue that has particularly come to the forefront during the Covid-19 pandemic as many people who have contracted the virus report a loss of taste and smell as their main symptoms.
Rapid tests effectively broke Covid-19 infection chains in spring 2021. This is shown by a model developed by researchers of the ECONtribute: Markets & Public Policy Cluster of Excellence of the Universities of Bonn and Cologne, the Collaborative Research Center Transregio 224 EPoS of the Universities of Bonn and Mannheim, and the Institute for the Study of Labor (IZA). According to the…
A pandemic is not a game. Yet, human response in dealing with Covid-19 resembles patterns known from games: people hoard resources, compare leaderboards and graphs, play certain social roles, establish a good-versus-evil narrative, and align themselves with prominent hero figures. The reasoning behind this is simple.
When patients are admitted to a hospital emergency room (ER) it is immediately vital to determine whether s/he has Covid-19. However, with a regular PCR test a result can take up to a few hours. Thus, initially, the patient must be isolated. During the height of the corona pandemic last year, researcher Ruben Deneer from Eindhoven University of Technology (TU/e) and clinical chemist Arjen-Kars…
Aerosol generated by playing woodwind and brass instruments is less than that produced when vocalising (speaking and singing) and is no different than a person breathing, new research has found. The findings could be crucial to developing a roadmap for lifting Covid-19 restrictions in the performing arts, which have been significantly restricted since the start of the pandemic.
234 random passersby got the opportunity to try a new virtual reality game, when researchers from the University of Copenhagen visited Fælledparken to test the efficiency of VR technology within health information. During the event, the participants tried their strength against a new VR game that simulates the effect of herd immunity. The game is developed by researchers at the Virtual Learning…
A new paper on long-Covid describes persistent symptoms six months after acute Covid-19, even in young home isolated people. The study from the Bergen Covid-19 Research Group, which was published in the journal Nature Medicine, followed infected patients during the first pandemic wave in Bergen. "The main novel finding is that more than fifty per cent of young adults up to 30 years old,…
In-vitro-diagnostics company bioMérieux has launched Episeq SARS-CoV-2, a genomic software solution to support microbiology labs in identification and reporting from raw sequencing data related to SARS-CoV-2 variants. Viral mutation is a naturally occurring phenomenon leading to the emergence of variants that can have different characteristics. Today, a number of SARS-CoV-2 variants are…
Epstein-Barr virus (EBV) reactivation resulting from the inflammatory response to coronavirus infection may be the cause of previously unexplained long Covid symptoms—such as fatigue, brain fog, and rashes—that occur in approximately 30% of patients after recovery from initial Covid-19 infection. The first evidence linking EBV reactivation to long Covid, as well as an analysis of long Covid…
Researchers from the German Center for Infection Research (DZIF) at Charité – Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage. According to their report in Nature Communications, the researchers were able to identify four substances which inhibit SARS-CoV-2…
The effects of Covid-19 on the brain can be accurately measured with positron emission tomography (PET), according to research presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2021 Annual Meeting. In the study, newly diagnosed Covid-19 patients, who required inpatient treatment and underwent PET brain scans, were found to have deficits in neuronal function and…
La Trobe University researchers are the first in the world to characterize precisely how Covid-19 attacks lung tissues — an important step in preventing long-term damage.
Digital transformation has been a significant factor in the way hospitals have responded to the challenges posed by the COVID-19 pandemic. However, at HIMSS21 European Health Conference, experts were also quick to point out that the approach of the ‘human resource’ to the challenges and changes was a key factor.
Women are missing out on appropriate cardiac care because guidelines and medications often fail to take into account gender and conditions that specifically affect the female population. Women are also underrepresented in clinical trials for new cardiac therapies.
Higher levels of vaccination against COVID-19 were associated with lower rates of infection with SARS-CoV-2 among a group of unvaccinated people of 16 years of age and under.
Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have published the first detailed atomic-level model of the SARS-CoV-2 "envelope" protein bound to a human protein essential for maintaining the lining of the lungs.
New artificial intelligence (AI) technology to scan for heightened blood vessel inflammation can calculate a person’s risk of death from Covid-19 and its variants.
A team of Johns Hopkins researchers has developed a rapid blood test that could confirm a person has been vaccinated while they wait to board a plane or enter a sporting event.
Mining the world's most comprehensive drug repurposing collection for Covid-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.
University of Washington researchers have discovered that AI models—like humans—have a tendency to look for shortcuts. In the case of AI-assisted disease detection, these shortcuts could lead to diagnostic errors if deployed in clinical settings.
Identifying new uses for approved therapeutic drugs continues to drive academics and clinicians to provide safe, affordable and rapid development of new treatment options for patients with common or rare diseases.
Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.
People with long Covid could be monitored with the aid of a ground-breaking mobile phone app and clinical website. The system has been developed to help NHS rehabilitation teams manage the large number of people suffering from the debilitating effects of the illness. Patients will also be able to use the app to track their recovery. The app will initially be available to patients in 27 NHS trusts…
Communities benefit from sharing knowledge and experience among their members. Following a similar principle - called “swarm learning” - an international research team has trained artificial intelligence algorithms to detect blood cancer, lung diseases and Covid-19 in data stored in a decentralized fashion. This approach has advantage over conventional methods since it inherently provides…
One of the negative impacts of the coronavirus pandemic has been the suspension or postponement of many cancer screening services. Each year, these services help prevent and detect the presence of cancer at an early stage; timely diagnosis and care are crucial in preventing the spread of cancer. The National Screening Observatory has confirmed this, reporting alarming statistics: during the first…
For the first time, a prospective, international study has shown that chest pain caused by problems with the very small vessels supplying blood to the heart is an important health problem that increases the risk of heart attacks, stroke and death due to cardiovascular reasons. The study, which is published in the European Heart Journal, recruited 686 patients from 14 institutions in seven…
A study of healthcare workers shows they were three times more likely to become infected during the Covid-19 pandemic compared to the general population. Around one in five of workers who were infected were asymptomatic and unaware they had Covid-19. The study published in ERJ Open Research also shows that it was not only frontline staff who faced the higher risk, suggesting that there was…
New regulations covering medical devices are set to come into effect across Europe. Originally intended to be implemented in May 2020, the introduction of the updated Medical Device Regulation (MDR) was delayed because of the coronavirus pandemic. The new regulations – the first major update in three decades – now come into force on May 26, and to mark the date a special conference discussed…
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune response in COPD patients.
Cities harbour a dangerous cocktail of environmental stressors which politicians must tackle to save lives and preserve health. That’s the conclusion of a paper published in European Heart Journal, a journal of the European Society of Cardiology (ESC). “By 2050, three in four people will live in cities, where up to 80% of energy is consumed and 70% of greenhouse gases are emitted,” said…
One in 7 (14%) adults with coronavirus infection developed at least one new condition that required medical care during the post-acute phase of illness, which is 5% higher than adults with no coronavirus infection in 2020, finds a US study published by The BMJ. The post-acute phase in this study started 21 days (or 3 weeks) after initial infection.
Almost 1 million extra deaths relating to the Covid-19 pandemic occurred in 29 high income countries in 2020, finds a study published by The BMJ. Except for Norway, Denmark and New Zealand, all other countries examined had more deaths than expected in 2020, particularly in men. The five countries with the highest absolute number of excess deaths were the US, UK, Italy, Spain, and Poland.
In Germany, more than 200,000 people suffer a heart attack every year. Despite good medical care, many are left with reduced cardiac output. This is particularly true for patients with severe heart attacks: more than 30 percent of those affected develop heart failure, and almost half of them die within the next five years. Experts at the Department of Cardiology and Angiology at Hannover Medical…
The Covid-19 pandemic made it clear technological innovations were urgently needed to detect, treat, and prevent the SARS-CoV-2 virus. A year and a half into this epidemic, waves of successive outbreaks and the dire need for new medical solutions — especially testing — continue to exist. In the Journal of Vacuum Science & Technology B, researchers from the University of Florida and…
A low-cost, rapid diagnostic test for Covid-19 developed by Penn Medicine provides Covid-19 results within four minutes with 90 percent accuracy. A paper published this week in Matter details the fast and inexpensive diagnostic test, called RAPID 1.0 (Real-time Accurate Portable Impedimetric Detection prototype 1.0). Compared to existing methods for Covid-19 detection, RAPID is inexpensive and…
Delaying the second dose of Covid-19 vaccines, at least for people aged under 65, could result in up to 20% lower mortality, but only under certain conditions, finds a US study published by The BMJ. These conditions include a one dose vaccine effectiveness (efficacy) of 80% or higher and vaccination rates of 0.1% to 0.3% of the population per day. If these conditions apply, the researchers say…
Researchers used AI to identify which daily changing clinical parameters best predict intervention responses in critically ill Covid-19 patients. The investigators used machine learning to predict which patients might get worse and not respond positively to being turned onto their front in intensive care units (ICUs) - a technique known as proning that is commonly used in this setting to improve…
An appeal is launched for Health Ministries across Europe to sign the Declaration for Action on the Stroke Action Plan for Europe to tackle one of the leading causes of death and disability. Led by The European Stroke Organisation (ESO) and Stroke Alliance for Europe (SAFE), the initiative aims to encourage European countries to show their commitment to improving stroke prevention, treatment,…
When a cell is infected, SARS-CoV-2 not only causes the host cell to produce new virus particles. The virus also suppresses host cell defence mechanisms. The virus protein nsP3 plays a central role in this. Using structural analyses, researchers at Goethe University in cooperation with the Swiss Paul Scherrer Institute have now discovered that a decomposition product of the virostatic agent…
A large study from Denmark and Norway published by The BMJ sheds more light on the risk of rare blood clots in adults receiving their first dose of the Oxford-AstraZeneca Covid-19 vaccine. The findings show slightly increased rates of vein blood clots including clots in the veins of the brain, compared with expected rates in the general population. However, the researchers stress that the risk of…
The use of Silver-based medical products has always been prevalent in hospital settings to kill bacteria instantly. As the Covid-19 pandemic rages on and many look for practical PPE equipment, manufacturer Suprcare launches its 'Suprmask' with Pure Silver technology. In addition, it can be reused without having to be washed.
Clinical diagnostics company Beckman Coulter announced the European launch of the DxA 5000 Fit, a workflow-automation solution designed to fit into medium-sized labs that run fewer than 5,000 tests a day. The clinical laboratory has gone through trial by fire in 2020, where total testing was 245% of baseline volumes, with ~55% being SARS-CoV-2 molecular tests. Despite vaccines, many industry…
Medical robotics company Robocath announces the successful completion of first five robotic coronary angioplasties in Belgium. The Percutaneous Coronary Interventions (PCI) were performed on April 8 and 13 by Prof. Stefan Verheye, a recognized and highly experienced interventional cardiologist at ZNA Middelheim hospital in Antwerp, and his team. Robotic-assisted PCI has never been done before in…
A collaboration spanning four research labs and hundreds of miles has used the organ-on-a-chip (Organ Chip) technology from the Wyss institute at Harvard Univesity to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes Covid-19. The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the…
Should outdoor face covering be normalised to reduce transmission of SARS-CoV-2—or should anti-Covid efforts rather focus on indoor protection? Experts argue the case for both sides in this controversial debate.
Diagnostic data from the massive amounts of testing being conducted can help make health systems more resilient in dealing with future health crises and pandemics. The importance of diagnostic data was explored during the Medtech Europe online session, “Unlocking the Value of Diagnostic Information – how to make European Health Systems more resilient?” where delegates heard that…
Researchers from Cleveland Clinic and Case Western Reserve University collaborate on genetic study of SARS-CoV-2 mutations. Results show how the different COVID-19 clades evolved.
Advice on the application of the Medicrime Convention in the context of counterfeit COVID-19 vaccines.
A major study from the Washington University School of Medicine details numerous long-term effects of COVID-19, pointing to massive health burden.
Fluxergy envisions that a fully articulated democratized testing health system has the potential to reduce the likelihood and the ultimate severity of pandemics like Covid-19. Our mission is to unlock the true potential of diagnostics to play a far greater and more important role in the early detection of diseases and ongoing monitoring of health status, where and when it matters most: at the…
Vigorous and rapid air exchanges might not always be a good thing when it comes to addressing levels of coronavirus particles in a multiroom building, according to a new modeling study. The study suggests that, in a multiroom building, rapid air exchanges can spread the virus rapidly from the source room into other rooms at high concentrations. Particle levels spike in adjacent rooms within 30…
The largest study of its kind in the UK has identified differences in the immune response to Covid-19 between people with no symptoms, compared to those suffering a more serious reaction to the virus. The research by Newcastle University and collaborators within the Human Cell Atlas initiative found raised levels of specific immune cells in asymptomatic people. They also showed people with more…
A team led by a clinical academic at University College London (UCL) has outlined the mechanism behind rare cases of blood clots and low platelets seen in patients who have had the Oxford/AstraZeneca vaccine. The new study, published in the New England Journal of Medicine, highlights the importance of rapidly spotting this new syndrome, known as vaccine-induced thrombosis and thrombocytopenia…
The pandemic could challenge what little achievement has been made so far in the field, a prominent Spanish medical oncologist explained during the virtual European Lung Cancer Conference
What happens when patients can no longer breathe on their own and need to be supported by machines? How far does infected air spread throughout a room? And what safety precautions do medical and nursing staff need to take? Respiratory specialists Dr. Dominic Dellweg and Dr. Jens Kerl together with Dr.-Ing. Conrad Völker, Amayu Wakoya Gena, and Dr. Hayder Alsaad from the Department of Building…
Coronavirus researchers under Prof. Rolf Hilgenfeld of the University of Lübeck and Dr. Albrecht von Brunn of the Ludwig-Maximilians University of Munich discovered how SARS viruses enhance the production of viral proteins in infected cells, so that many new copies of the virus can be generated. Other coronaviruses apart from SARS-CoV and SARS-CoV-2 do not use this mechanism, thereby providing a…
New research by University of Texas at Dallas scientists could help solve a major challenge in the deployment of certain Covid-19 vaccines worldwide — the need for the vaccines to be kept at below-freezing temperatures during transport and storage. In a study published online in Nature Communications, the researchers demonstrate a new, inexpensive technique that generates crystalline…
When it comes to Covid-19, women seem to be the stronger sex, suffering severe disease at about half the rate as men, but the reason for this has been elusive. Now a chance experiment by an ophthalmology researcher at Duke Health has led to an insight: Women have more of a certain type of immune cell that fights infections in mucosal tissue, and these immune cells amass in the lungs, poised to…
Researchers at the University of Oxford report that the risk of the rare blood clotting known as cerebral venous thrombosis (CVT) following Covid-19 infection is around 100 times greater than normal, several times higher than it is post-vaccination or following influenza. The study authors, led by Professor Paul Harrison and Dr Maxime Taquet from Oxford University’s Department of Psychiatry and…
Any future attempts to reduce the spread of Covid-19 should be focused on tackling close airborne transmission of the virus which is considered to be the primary route for its circulation, according to experts. Respiratory experts argue that it is now clear that SARS-CoV-2 is most likely to transmit between people at close range through inhalation rather than through contact with surfaces or…
Researchers running the Com-Cov study, launched in February to investigate alternating doses of the Oxford-AstraZeneca vaccine and the Pfizer vaccine, announce that the programme will be extended to include the Moderna and Novavax vaccines in a new study.
Does overcoming a SARS-CoV-2 infection protect against reinfection? The “Rhineland Study”, a population-based study conducted by DZNE in the Bonn area, is now providing new findings in this regard. Blood samples taken last year indicate that an important component of immunity – the levels of specific neutralizing antibodies against the coronavirus - had dropped in most of the study…
SARS-CoV-2 is the virus responsible for the Covid-19 pandemic. We know that mutations in the genome of SARS-CoV-2 have occurred and spread, but what effect do those mutations have? Current methods for studying mutations in the SARS-CoV-2 genome are very complicated and time-consuming because coronaviruses have large genomes, but now a team from Osaka University and Hokkaido University have…
Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms’ DNA. While the system could potentially be useful in treating a variety of diseases, CRISPR-Cas9 editing involves cutting DNA strands, leading to permanent changes to the cell’s genetic material. Now, in a paper published online in Cell,…
Now Available: The Fluxergy Analyzer System is a testing platform designed for sample-to-answer point-of-care testing, enabling clinicians to cost-effectively conduct molecular in vitro diagnostic tests. The analyzer system is designed to deliver test results within one hour. This device is solely intended to be used by healthcare professionals.
Antimicrobial technologies such as coatings and textiles containing silver and copper are helping people during the Covid-19 pandemic by ensuring that whatever they touch, whether that is a door handle or their own mask, is free from live SARS-CoV-2 particles. But how exactly do these antimicrobial technologies work? How can a silver, copper or even polymeric coating kill microorganisms such as…
A new report shows how palliative and end of life care in the UK was compromised by shortages of PPE, essential medicines, and equipment, because these services were not seen as ‘frontline NHS’ in the pandemic. Better End of Life – a collaboration between Marie Curie, Hull York Medical School, University of Hull, King’s College London Cicely Saunders Institute, and the University of…
Clinicians using a new viral screening test can not only diagnose Covid-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses—like influenza—that might be mistaken for the coronavirus. At the same time, they can sequence the virus, providing valuable information on the spread of Covid-19 mutations and variants. The new test, dubbed…
People discharged from hospital after Covid-19 appear to have increased risks of diseases across multiple organs and nearly a third are readmitted to hospital in the following months, according to a new study co-led by researchers at University College London. The study, published in The BMJ, looked at nearly 50,000 people who were discharged from hospital by August last year and compared them to…
A University of Manchester team has applied new techniques to detect and track the transmission of Covid-19 in hospital. The proof of concept system combines the movement and interaction of staff and patients with genomic sequencing of the virus, helping to signpost how best to improve patient pathways, staff movement and reduce risk. They identified hotspots within hospitals where patients and…
Recovery duration, co-morbidities, mortality, risk groups: A large UK study reports in detail on 'Long Covid'. We spoke with two of the study's co-investigators about why so many patients are still affected after a coronavirus infection.
Skin swab samples analysed using mass spectrometry could be used to detect Covid-19 in patients, according to research conducted at the University of Surrey in the UK. Current Covid-19 testing is via a polymerase chain reaction (PCR) test, which involves taking a swab of the back of the throat and inside the nose, but the team from Surrey - working with Frimley NHS Trust and the Universities of…
New research has shown that results of blood tests routinely performed by GPs everywhere contain a hidden fingerprint that can identify people silently developing potentially fatal liver cirrhosis. The researchers have developed an algorithm to detect this fingerprint that could be freely installed on any clinical computer, making this a low-cost way for GPs to carry out large scale screening…
The first known study to measure SARS-CoV-2 viral load in a variety of organs and tissues may aid our understanding of how Covid-19 develops following infection.
In the largest study of its kind to date, researchers at Massachusetts General Hospital, Brigham and Women’s Hospital and the Ragon Institute of MGH, MIT and Harvard have found the new mRNA Covid-19 vaccines to be highly effective in producing antibodies against the SARS-CoV-2 virus in pregnant and lactating women. They also demonstrated the vaccines confer protective immunity to newborns…
Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes. It is faster and cheaper than a conventional blood count. To demonstrate the technique’s potential, the researchers used blood plasma collected from Covid-19 patients.…
More than four in five (86%) people who were unsure or said no to a Covid-19 vaccine in December 2020 would now take one, or have already been vaccinated, finds the latest research by the Virus Watch study conducted by University College London (UCL).
The Institute for Research in Biomedicine (IRB) in Switzerland developed a second-generation ‘double antibody’ that protects from SARS-CoV-2, the virus causing Covid-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy. Antibody-based immunotherapy was already shown to be effective against Covid-19 but faces two main obstacles: it needs to work…
Scientists from Singapore found that antibodies against SARS-CoV-2 wane at different rates, lasting for mere days in some individuals, while remaining present in others for decades. The study, published in The Lancet Microbe, shows that the severity of the infection could be a deciding factor in having longer-lasting antibodies. Individuals with low levels of neutralising antibodies may still be…
Researchers are developing a COVID-19 vaccine that could provide protection against both existing and future strains of the COVID-19 virus, and other coronaviruses, and cost about $1 a dose has shown promising results in early animal testing.
Researchers at University of Toronto have developed a new test to accurately detect coronavirus antibodies in a drop of blood in less than an hour.
Thermo Fisher Scientific and Artificial have announced a strategic technology collaboration to develop an integrated and comprehensive software automation platform for Thermo Fisher’s standardized COVID-19 Testing Platform. The integration will result in increased testing throughput and support global healthcare initiatives.
Researchers from Cleveland Clinic’s Florida Research and Innovation Center (FRIC) have identified a potential new target for anti-COVID-19 therapies.
Researchers investigated whether the vaccine recipients developing unusual thrombotic events and thrombocytopenia could have a prothrombotic disorder caused by platelet-activating antibodies directed against a platelet protein, as a similar mechanism is known to be caused by heparin and sometimes other environmental triggers.
A study conducted by Columbia University Mailman School of Public Health researchers reports a high global prevalence of both depression and anxiety during the Covid-19 pandemic. It also shows how the implementation of mitigation strategies including public transportation and school closures, and stay-at-home orders impacted such disorders. Results are published in Psychological Medicine.
Even as vaccines are becoming more readily available, protecting against the asymptomatic and pre-symptomatic spread of the virus (SARS-CoV-2) that causes Covid-19 is key to ending the pandemic, say two infectious disease experts at the Georgetown University Medical Center. In their Perspective, “SARS-CoV-2 Transmission Without Symptoms,” published in the journal Science, they make the case…
Moderna and IBM announced their intentions to explore technologies, including artificial intelligence, blockchain and hybrid cloud, that could help support smarter Covid-19 vaccine management. Central to the effort will be a pilot of open, standardized, technology-enabled vaccine distribution approaches aimed to improve supply chain visibility and foster near real-time tracking of vaccine…
A study published by The BMJ sheds light on the risk of infection with SARS-CoV-2 and covid-19 outcomes among adults living with and without children during the first two waves of the UK pandemic. It finds no evidence of any increased risk in wave 1 (Feb to Aug 2020). Small increased risks of infection and hospital admission were seen in wave 2 (Sept to Dec 2020), but this did not translate into…
Rapid tests, PCR tests, self-tests… there are many test options to determine contamination with Covid-19. In most this is done by inserting a cotton swab deep into the nose and/or throat to extract some mucus – unpleasant for adults and often a drama for children. Towards the end of 2020, a new system emerged to rule out a Covid-19 contamination. The electronic SpiroNose performs a…
Liquid metal bearing (LMB) technology has been a key aspect of extending the lifespan of CT scanners, improving workflow, and enhancing patient and operator experience via noise reduction. The LMB concept has been pioneered by Dunlee, with senior CT product manager Robert Bayerlein noting that the Hamburg-based company has a long heritage in imaging innovation.
In what is believed to be the first published study of Covid-19 vaccine effectiveness in long-term care facilities such as nursing homes, a research team co-led by the Yale School of Public Health found a widely used vaccine is highly successful in preventing infections. Residents of such facilities, particularly those in skilled nursing facilities (SNFs), have experienced disproportionately high…
Systematic review finds that machine learning models for detecting and diagnosing Covid-19 from medical images have major flaws and biases, making them unsuitable for use in patients. However, researchers have suggested ways to remedy the problem. Researchers have found that out of the more than 300 Covid-19 machine learning models described in scientific papers in 2020, none of them is suitable…
The results of a large-scale study indicate that the introduction of an AI-powered solution by healthcare software company Radlogics into radiology workflow to analyze Chest-CT scans during the Covid-19 pandemic reduced report turnaround time by an average of 30 percent, which is equivalent to 7 minutes per case.
During pandemics, protective behaviors need to be motivated by effective communication. A critical factor in understanding a population’s response to such a threat is the fear it elicits, since fear both contributes to motivating protective responses, but can also lead to panic-driven behaviors. Furthermore, lockdown measures affect well-being, making it important to identify protective factors…
The highly infectious variant of Covid-19 discovered in Kent, which swept across the UK last year before spreading worldwide, is between 30 and 100 per cent more deadly than previous strains, new analysis has shown. A pivotal study, by epidemiologists from the Universities of Exeter and Bristol, has shown that the SARS-CoV-2 variant, B.1.1.7, is associated with a significantly higher mortality…
Chest pain is misdiagnosed in women more frequently than in men, according to research presented at ESC Acute CardioVascular Care 2021, an online scientific congress of the European Society of Cardiology (ESC). The study also found that women with chest pain were more likely than men to wait over 12 hours before seeking medical help. “Our findings suggest a gender gap in the first evaluation of…
Miniature cameras which patients can swallow to get checked for cancer are being trialled across the NHS. The imaging technology, in a capsule no bigger than a pill, can provide a diagnosis within hours. Known as a colon capsule endoscopy, the cameras are the latest NHS innovation to help patients access cancer checks at home. Traditional endoscopies mean patients need to attend hospital and have…
Magnetic resonance imaging (MRI) is widely used to identify the narrowing or blockage of blood vessels. Contrast agents improve the visibility of the structures and offer more accurate information of vascular conditions such as vascular blockage and stenosis. Commonly used gadolinium-based contrast agents must be administered in chelated forms due to the gadolinium ions' high toxicity and pose…
During a pandemic, the demands for laboratory testing challenge routines in an efficiently run clinical laboratory. Gold standard procedures may need modification, or to be discarded, and the more nimble, resilient and receptive a lab is to change, the better off it could be. Senior managers at ARUP Laboratories in Salt Lake City, Utah, a large clinical reference laboratory that offers over 3,000…
Despite Brexit uncertainties, four leading UK cancer research experts expressed optimism for continued pan-European collaboration and innovation during the online panel debate ‘Brexit deal: What it really means for cancer research and innovation’ hosted by the National Cancer Research Institute (NCRI).
Cardiac surgery across Europe is being set back as a result of the ongoing coronavirus. Operations are being postponed, treatment delayed, and critical care staff have been redeployed to cope with the impact of the Covid-19 epidemic on health services. However, gaining a clear picture of the Europe-wide situation, and the long-term effects coronavirus will have on heart surgery, is a challenge…
When airborne pollen levels are higher, increased SARS-CoV-2 infection rates can be observed. These results were determined by a large-scale study conducted by an international team headed by researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München. Members of high-risk groups could protect themselves by watching pollen forecasts and wearing dust filter masks.
In order to monitor and contain the spread of SARS-CoV-2 it is necessary to test large numbers of people on a regular basis in decentralized settings. Researchers of the Max Planck Institute for Evolutionary Anthropology and the Hospital St. Georg in Leipzig, Germany, have developed improved protocols for the detection of SARS-CoV-2. The method can detect a positive sample in a pool with 25…
Digital Covid-19 ‘symptom checkers’ may stop some patients from getting prompt treatment for serious illness, suggests an international case simulation study. Both the US and UK symptom checkers consistently failed to identify the symptoms of severe Covid-19, bacterial pneumonia, and sepsis, frequently advising these cases to stay home, the findings indicate. The availability and use of…
Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex and also rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL), together with international partners, have studied genotype-phenotype relationships in iPSCs using data from approximately one thousand donors. Tens of…
A global group of researchers is calling for better integration of viral genetics, bioinformatics, and public health to enable better pandemic response now and better pandemic preparedness in the future. In a comment piece in the journal Nature, an international collaboration of specialists in viral and genetic analysis, led by Swiss scientists Dr. Emma Hodcroft at the University of Bern and…
With a growing number of Artificial Intelligence (AI) algorithms to support medical imaging analysis, finding the best solution for specific radiology tasks is not always straightforward. Many are cloaked in secrecy and commercial sensitivity and while an algorithm may perform well in one area, evidence of performance and adaptability in another environment is not always available.
A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease. The study is based on laboratory experiments. Extensive clinical trials are still required for their further development as…
The impact of Covid-19 has been devastating; countless lives lost, millions of infections worldwide, health systems overwhelmed and economies rapidly shrinking. Screening, such as for breast or cervical cancer, is an area particularly affected, with numerous appointments delayed.
Improving workflow is one of the major challenges that radiology departments face. The need to be more efficient, deliver timely and effective patient care, and keep an eye on costs are all factors that seem to be ever-present in the modern imaging department. With the added demands of the coronavirus pandemic as radiology departments continue to play a critical role in the fight against…
Pan-European lung cancer screening is challenged due to the range of approaches in different countries. As attitudes towards smoking and smoking cessation programmes vary, experts are attempting to establish more unified lung cancer screening. The introduction of consistent pan-European lung cancer screening will be outlined at a special session during the online ECR 2021, with presentations…
Due to the coronavirus, hospitals and medical staff developed new work practices involving, in acute settings, social distancing, rigid use of personal protective equipment (PPE), handwashing, and disinfection of equipment every day. Additionally, portable, highly-mobile and versatile equipment came to the fore in point-of-care (POC) – particularly when wards and operating theatres are spread…
With public health issues continuing to make daily mainstream news headlines across the world, it is clear how much change the healthcare environment is going through. Not only are there existing pressures on resources, space, staff, certain procedures, and budgets, but there are brand new ones resulting from the ongoing global COVID-19 pandemic. This has led to an even greater need for…
Computer modelling to forecast Covid-19 mortality contains significant uncertainty in its predictions, according to an international study led by researchers at University College London (UCL) and Centrum Wiskunde & Informatica (CWI) in the Netherlands. Their article ‘The Impact of Uncertainty on Predictions of the CovidSim Epidemiological Code’ was published in Nature Computational…
Temperature control equipment and systems company Lauda is expanding its portfolio with its new Versafreeze product line. This consists of high-quality ultra-freezers which have been optimized for the extreme requirements of deep-freeze storage. Lauda thereby meets the requirements of vaccine producers, pharmaceutical service providers, vaccination centers and universities for the safe storage of…
The European Commission has launched a contingency plan to meet the challenge of the various mutations of the coronavirus. Karolinska Institutet and Karolinska University Hospital are contributing to a new network for the evaluation and testing of new vaccines. The network is called "Vaccelerate" and it will contribute both to the evaluation of ongoing and future vaccinations, as well…
Scientists have developed peptides that fit snugly into a groove on the SARS-CoV-2 Spike protein that it would normally use to access a host cell. These protein fragments effectively trick the virus into “shaking hands” with a replica rather than with the actual protein on a cell’s surface that lets the virus in. revious research has determined that the novel coronavirus binds to a receptor…
For many women, swollen lymph nodes are a red flag pointing to breast cancer – but may also be a normal immune reaction to a Covid-19 vaccination. In this Q&A, breast imaging experts address the most important facts on the topic.
Covid-19 vaccine passports could be created, but significant challenges need to be overcome first, according to a report from a panel led by Oxford Professors Melinda Mills and Chris Dye, which outlines a dozen issues which must be addressed before passports can be introduced. The report is published by the SET-C (Science in Emergencies Tasking: Covid-19) group at the Royal Society and it…
Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. In the latest predictions for cancer deaths in the EU and UK for 2021, published in the cancer journal Annals of Oncology, researchers led by Carlo La Vecchia (MD), a professor…
AI-based vocal biomarker company Vocalis Health announced results of a clinical study conducted in collaboration with the Municipal Corporation of Greater Mumbai (MCGM) at their NESCO Covid-19 Center to validate Vocalis Health’s Covid-19 screening tool, VocalisCheck. The study included over 2,000 participants who spoke numerous languages including English, Hindi, Marathi and Gujarati. Results…
Hospital data from a wide range of disciplines, departments and specialties strongly influences crucial decision-making and planning. Agfa HealthCare’s Business Intelligence solution, for example, uses data to measure, understand and predict developments, and aims to present this information in an accessible and transparent way so that administrators need not even ask for in-house generated…
Apheresis, a procedure that separates and removes particular blood constituents, shows promise for Covid-19 cases: the first patient successfully underwent so-called CRP apheresis, which can prevent potentially fatal consequences of the infection.
Preventing air contamination in healthcare facilities is crucial to minimise the airborne spread of Covid-19 and its new strains. Universal masking, rigorous use of and safe disposal of PPE, plus building ventilation are vital. Twenty-four studies reporting hospital SARS-CoV-2 air contamination are summarised in a meta-analysis by a multi-institutional team of French researchers. These show that,…
Researchers at ZHAW Zurich University of Applied Sciences are working with the Swiss company Osmotex AG to develop a self-disinfecting mask that inactivates viruses at the push of a button. The prototype of this mask made of electrochemical textiles shows an antiviral effect of over 99 percent. Further applications such as sterilizable seat covers are being examined.
Around 50% of patients who have been hospitalised with severe Covid-19 and who show raised levels of a protein called troponin have damage to their hearts. The injury was detected by magnetic resonance imaging (MRI) scans at least a month after discharge, according to new findings published in the European Heart Journal. Damage includes inflammation of the heart muscle (myocarditis), scarring or…
The impact of Covid-19 in Africa has been vastly underestimated, warn researchers in a new study. Outside of South Africa, this is the first study to provide systematic surveillance data capturing the impact of Covid-19 in Africa. Their findings are based on polymerase chain reaction (PCR) test results for 364 deceased people of all ages at the University Teaching Hospital morgue in Lusaka,…
To date, testing for SARS-CoV-2 infection mostly has relied on RT-PCR performed on a nasopharyngeal specimen. This testing method is very unpleasant for a patient: the professional tester has to tilt the patient’s head back slightly about 45°-70° to straighten the passage from the front of the nose, insert the swab through the nostril parallel to the palate, and the swab should reach a depth…
A team of researchers studying the effectiveness of different types of face masks has found that in order to provide the best protection against Covid-19, the fit of a mask is as important, or more important, than the material it is made of. The researchers, from the University of Cambridge, carried out a series of different fit tests, and found that when a high-performance mask – such as an…
Is there a better approach to Covid drug research? Research from the University of Kent, Goethe-University in Frankfurt am Main, and the Philipps-University in Marburg has provided crucial insights into the biological composition of SARS-CoV-2, the cause of Covid-19, revealing vital clues for the discovery of antiviral drugs. Researchers compared SARS-CoV-2 and the closely related virus SARS-CoV,…
The PCR test is the most accurate tool to identify SARS-CoV-2. However, valid results are often available only after days. Moreover, the laboratory must be well equipped, have trained personnel and sufficient financial resources. All of this is usually a problem in Africa. A portable suitcase could help. In cooperation with several African universities, scientists at Leipzig University have found…
University of Minnesota Medical School researchers studied SARS-CoV-2 infections at individual cellular levels and made four major discoveries about the virus, including one that validates the effectiveness of remdesivir – an FDA-approved antiviral drug – as a form of treatment for severe Covid-19 disease. “Since the start of the Covid-19 pandemic, the way that each individual responds…
Patients given preventive blood thinning drugs (prophylactic anticoagulants) within 24 hours of admission to hospital with Covid-19 are less likely to die compared with those who do not receive them, a new study finds. Clinical trials are now underway to see if prophylactic anticoagulants could be an effective treatment for Covid-19. In the meantime, the researchers say these findings provide…
Scientific and public health experts have been raising the alarm for decades, imploring public officials to prepare for the inevitability of a viral pandemic. Infectious epidemics seemingly as benign as "the flu" and as deadly as the Ebola virus provided ample warning, yet government officials seemed caught off guard and ill prepared for dealing with Covid-19.
People who are sceptical of getting vaccinated against infectious diseases may soon get a whole new perspective on things. Professor Robert Böhm and Associate Professor Guido Makransky from the Center for Social Data Science (SODAS) and the Department of Psychology at the University of Copenhagen have received DKK three million in funding from EIT Health for developing a virtual reality app to…
Wearable devices can identify Covid-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, Mount Sinai researchers report in one of the first studies on the topic. The findings were published in the Journal of Medical Internet Research. The Warrior Watch Study found that subtle changes in a participant’s heart rate variability (HRV)…
The first evidence from genetic data that high blood pressure is causally associated with the most common heart rhythm disorder is published in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).
Medics.Academy – a UK company delivering global access to medical education – and the Ethiopian Medical Women’s Association (EMeWA) have signed a partnership agreement to help women physicians in Ethiopia. The project will help EMeWA – an organisation established by female physicians in Ethiopia – to fulfil its vision to establish an excellence center for women physicians through one of…
Global greenhouse gas emissions over the last century have made southern China a hotspot for bat-borne coronaviruses, by driving growth of forest habitat favoured by bats. A new study published in the journal Science of the Total Environment provides the first evidence of a mechanism by which climate change could have played a direct role in the emergence of SARS-CoV-2, the virus that caused the…
Researchers from the University of Nottingham have discovered a novel antiviral property of a drug that could have major implications in how future epidemics/pandemics – including Covid-19 – are managed. The study, published in Viruses, shows that thapsigargin is a promising broad‑spectrum antiviral, highly effective against SARS-CoV-2, a common cold coronavirus, respiratory syncytial virus…
USC researchers have developed a new method to counter emergent mutations of the coronavirus and hasten vaccine development to stop the pathogen responsible for killing thousands of people and ruining the economy.
Covid-19 patients who suffer a cardiac arrest either in or out of hospital are far more likely to die than patients who are not infected with the coronavirus. In particular, women have the highest risk of dying: they are nine times more likely to die after suffering a cardiac arrest in hospital, according to research published in the European Heart Journal.
In order to detect the Corona virus SARS-CoV-2, there are further methods of diagnosis apart from the globally used PCR tests (Polymerase chain reaction): The infection can also be recognised on CT scans – for which Artificial Intelligence (AI) can be used as well. An AI system can not only filter CT scan of Covid-19 patients from a data set, but also estimate, which areas of the image are of…
Coronavirus-associated concerns dominate the Top 10 list of important technology hazard risks for hospitals, in an annual report published by ECRI, a nonprofit technology Pennsylvania research firm. The list is derived from ECRI’s team of technology experts who monitor hospital and healthcare organizations, and published to inform healthcare facilities about important safety issues involving…
The continuing corona virus epidemic has impacted strongly on cancer care and research, including the delay of treatments and diagnoses as well as on trials of new therapies, and the shift in research to develop a Covid-19 vaccine. However, the session ‘Cancer research and Covid-19’, during the National Cancer Research Institute (NCRI) Virtual Showcase (online 2-3 November) looked at how UK…
The most deadly global health crisis in a century has resulted in a substantial decline in overall heart surgery volume and an unexplained increase in deaths after coronary artery bypass grafting, according to late-breaking research presented at the 57th Annual Meeting of The Society of Thoracic Surgeons.
Researchers at the University of Arizona are developing a Covid-19 testing method that uses a smartphone microscope to analyze saliva samples and deliver results in about 10 minutes. The research team, led by biomedical engineering professor Jeong-Yeol Yoon, aims to combine the speed of existing nasal swab antigen tests with the high accuracy of nasal swab PCR, or polymerase chain reaction,…
Evidence is emerging that vitamin D – and possibly vitamins K and A – might help combat Covid-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they – and other antiviral drugs – might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so…
The emergence of SARS-CoV-2 virus variants that are adding twists in the battle against COVID-19 highlight the need for better genomic monitoring of the virus, says Katia Koelle, associate professor of biology at Emory University.
This FAQ from the American College of Allergy, Asthma and Immunology is provided to help answer patient questions about COVID-19 vaccines. These recommendations are based on best knowledge to date, but could change at any time, pending new information and further guidance from the FDA or CDC.
Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles' heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics.
As the pandemic has continued to spread globally, studies indicate the COVID-19 virus may be contained in aerosols that can be generated and spread through breathing, coughing, sneezing, or talking by infected individuals. Researchers are increasingly focused on developing tools and methods to assist in decontaminating surfaces and spaces.
The Belgian initiative icovid, which supports radiologists in the assessment of CT images of the lungs of COVID-19 patients, has grown into a multicentre European project, co-funded by the EU Horizon 2020 programme. Icovid was set up in March by UZ Brussel, KU Leuven, icometrix and ETRO, an imec research group of VUB.
As the first coronavirus vaccines started to be rolled out at the end of a tumultuous 2020, UK officials unexpectedly endorsed stretching the gap between the first and second vaccine dose by up to three months – an approach also considered by other countries.
Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too. Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and…
Clinical diagnostics company Beckman Coulter launched its Access SARS-CoV-2 IgG II assay in countries accepting the CE Mark. The new Access SARS-CoV-2 IgG II assay quantitatively measures a patient’s level of antibodies in response to a previous SARS-CoV-2 infection. The ability to establish a quantitative baseline to evaluate an individual’s immune response to the SARS-CoV-2 virus allows…
The corona pandemic, which has been rampant for a year, and the Ebola epidemic of 2017 have shown the value of online courses for the rapid worldwide dissemination of life-saving knowledge, the German Hasso Plattner Institute (HPI) points out. One year ago, the World Health Organization (WHO) published its first online course on Covid-19 diseases. HPI head Prof. Christoph Meinel reflects on its…
With Covid-19 dominating medical science and human concern, chemists at the University of Sydney have developed a method to quickly and safely synthesise protein vaccines for respiratory diseases for pre-clinical tests. Their approach can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes Covid-19.
Fried-food intake is linked to a heightened risk of major heart disease and stroke, finds a pooled analysis of the available research data, published online in the journal Heart. And the risk rises with each additional 114 g weekly serving, the analysis indicates. It’s clear that the Western diet doesn’t promote good cardiovascular health, but it’s not clear exactly what contribution fried…
One of the most vexing aspects of the Covid-19 pandemic is doctors’ inability to predict which newly hospitalized patients will go on to develop severe disease, including complications that require the insertion of a breathing tube, kidney dialysis or other intensive care. Knowledge of a patient’s age and underlying medical conditions can help predict such outcomes, but there are still…
According to current studies, the Covid-19 disease which is caused by the SARS-CoV-2 coronavirus comprises at least five different variants. These differ in how the immune system responds to the infection. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, together with other experts from Germany, Greece and the Netherlands, present these findings…
It is a simple image of two desks in a hospital pathology department, taken a matter of months apart. But there can be few more vivid images that illustrate the changing world of pathology as the specialty forges ahead into the digital era. The image was taken by Dr Solène-Florence Kammerer-Jacquet during the transition towards digital pathology at Rennes University Hospital in France in the…
Scientists at The Ohio State University have discovered a new variant of SARS-Cov-2, the virus that causes Covid-19. The new variant carries a mutation identical to the U.K. strain, but it likely arose in a virus strain already present in the United States. The College of Medicine researchers also report the evolution of another U.S. strain that acquired three other gene mutations not previously…
Researchers at Karolinska Institutet have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells. The research study, published in Science, shows that a combined nanobody had a particularly good effect – even if the virus mutated. According to the researchers, the…
An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage. In a new study, scientists identified a molecule that is produced by immune cells during mechanical ventilation to try to decrease inflammation, but isn’t able to completely prevent…
Siemens Healthineers announced CE mark has been achieved to use anterior nose swab sampling for the Clinitest Rapid Covid-19 Antigen test. This sampling method can be less cumbersome and time consuming for both the provider and the patient. The test is a point-of-care cassette test that does not require laboratory instruments or specialized lab personnel to administer, and it delivers results in…
Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body’s immune system within the first few days of the illness. But in a study published in Nature, investigators at Northwestern Medicine show Covid-19 pneumonia is…
Researchers at the University of Chicago have created the first usable computational model of the entire virus responsible for Covid-19—and they are making this model widely available to help advance research during the pandemic. “If you can understand how a virus works, that’s the first step towards stopping it,” said Prof. Gregory Voth, whose team created the model published in…
Even those who understand the scientific process, trust medical experts and know how important vaccines are for fighting infectious diseases might still have some questions or concerns about the new Covid-19 vaccines. Here, Thaddeus Stappenbeck, MD, PhD, helps set the record straight on 8 common questions, concerns and myths that have emerged about Covid-19 vaccines.
The variety and volume of bacteria in the gut, known as the microbiome, may influence the severity of Covid-19 as well as the magnitude of the immune system response to the infection, suggests research published online in the journal Gut. Imbalances in the make-up of the microbiome may also be implicated in persisting inflammatory symptoms, dubbed ‘long Covid’, the findings suggest. Covid-19…
In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study, which was published in Immunity, may contribute to future treatments for Covid-19, among other diseases.
So far, little research has been done on the risk of children being seriously affected by Covid-19 when the schools were open. A study from Karolinska Institutet has now shown that one child in 130,000 was treated in an intensive care unit on account of Covid-19 during the period March-June. The study has been published in New England Journal of Medicine.
Non-degradable prostheses for cardiovascular tissues can be used to replace heart valves and blood vessels, but they can’t stay in the body permanently. In two recent papers, researchers at the Eindhoven University of Technology (TU/e) in collaboration with a number of clinical partners, the Dutch Heart Foundation, and TU/e spin-off companies Suprapolix, Xeltis, and STENTiT have shown how…
Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza. But, within days of closing their campus lab space as part of Covid-19 precautions, they turned their attention to a vaccine for SARS-CoV-2, the virus that causes Covid-19. Although the coronavirus was outside the lab’s specific area of expertise,…
Patients with acute heart failure nearly double their risk of dying if they get Covid-19, according to new research. The small, single centre study highlights the need for patients with heart failure to take extra precautions to avoid catching Covid-19. “Our results support prioritising heart failure patients for Covid-19 vaccination once it is available,” said study lead investigator Dr.…
The Corona pandemic poses new challenges for health care facilities as well as manufacturers of health IT and medical technology. Marcel Herrmann, Marketing Manager Medical Imaging at JVCKenwood, explains in an interview what these are and how they can be solved.
ZTA Biotech, a Budapest-based biotech startup, has developed a Covid-19 antibody (IgG) test using the ELISA protocol. This new detection method represents a great step forward in determining if patients have had a coronavirus infection and if they might still have immunity to the disease. Early results have proven 100% in specificity after testing 280 samples, and 100% sensitivity by testing 260…
Scientists have developed a machine-learning method that crunches massive amounts of data to help determine which existing medications could improve outcomes in diseases for which they are not prescribed. The intent of this work is to speed up drug repurposing, which is not a new concept – think Botox injections, first approved to treat crossed eyes and now a migraine treatment and top cosmetic…
Reports from Imperial College regarding the spread and the effects of Covid-19 had considerable policy impacts in several European countries. But the models that informed the reports have considerable flaws, and are not sufficient to draw the conclusions that were published. This is according to researchers from universities including Linköping University (LiU), in an article in Nature.
The search for antiviral agents against the new coronavirus is in full swing. Using a novel approach, Bioinformaticians have now discovered a weakness in the virus that could be exploited for drug development. In a computer model, the scientists discovered a human enzyme that is crucial for the virus. When it was switched off in the model, the virus could no longer multiply.
This July, Fujifilm Sonosite launched Sonosite PX, its newest ultrasound system, in the midst of the Covid-19 pandemic. Diku Mandavia, M.D., Chief Medical Officer of Fujifilm Sonosite, sat down with sonographer and Sonosite’s Director of Marketing Development Jodi Miller to discuss how Sonosite’s newest ultrasound system can help frontline health care workers combat the pandemic and why…
The Covid-19 vaccine developed by Oxford University/AstraZeneca has been given regulatory approval by the Medicines and Healthcare products Regulatory Agency (MHRA) after meeting required safety, quality and effectiveness standards. Following a rigorous, detailed scientific review by the MHRA’s expert scientists and clinicians and on the basis of the advice of its scientific, independent…
The Covid-19 pandemic came as a shock but not a surprise. Bodies around the world have been warning for years of a novel disease that could wipe out millions and crash the global economy. In February 2019, Dr Jonathan Quick, chair of the Global Health Council, told Raconteur: “Our greatest fear is being blindsided by a new virus, most likely due to animal-human spill over, which then readily…
The identification of people wearing masks has often presented a unique challenge during the pandemic. A new study by researchers from BGU and York University in Canada reveals the impact of this predicament and its potentially significant repercussions. The findings were just published in the journal Scientific Reports.
Inspired by remotely controlled surgical robots, professor and Vici laureate Jaime Gómez Rivas turned the corona crisis into an opportunity. He started to transform his lab into a remotely controlled experimental facility. And with success: the first paper based on entirely remote measurements is about to be published. ‘As soon as the lockdown began in March, I sat down and had a chat with my…
AI can help tackle inequities and bias in healthcare but it also brings partiality issues of its own, experts explained in a Hot Topic session entitled "Artificial Intelligence and Implications for Health Equity: Will AI Improve Equity or Increase Disparities?" at RSNA.
A new method for visualizing breath that is exhaled while someone is speaking or singing could provide important new insights into how diseases such as Covid-19 spread and the effectiveness of face masks. “Scientists believe the SARS-CoV-2 virus is primarily spread through respiratory droplets that can be carried in the breath or expelled through coughing or sneezing,” said Thomas Moore from…
Scientists from Würzburg and the US have charted the first global atlas of direct interactions between SARS-CoV-2 RNA and human host cells. This may provide a starting point for novel treatments. SARS-CoV-2 infections pose a global threat to human health and a formidable research challenge. One of the most urgent tasks is to gain a detailed understanding of the molecular interactions between the…
A smart ring that generates continuous temperature data may foreshadow Covid-19, even in cases when infection is not suspected. The device, which may be a better illness indicator than a thermometer, could lead to earlier isolation and testing, curbing the spread of infectious diseases, according to a preliminary study led by UC San Francisco and UC San Diego.
Medicus AI announces the successful launch of its first live project under SafePlay, the digital platform supporting rapid antigen testing, which went live in partnership with Roche Diagnostics Germany and 21Dx in Munich this month. Medicus provides operators with a tech-enabled end-to-end solution that supports the logistical aspects of testing, managing the administrative workflow from…
Nearly twice as many people were admitted to hospital for Covid-19 at the height of the pandemic than were for influenza at the peak of the 2018/2019 flu season, a study of French national data published in The Lancet Respiratory Medicine journal has found (Covid-19, 89,530 patients vs influenza, 45,819 patients).
Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate. Scientists from Charité – Universitätsmedizin Berlin and from the Berlin Institute of Health (BIH), along with colleagues from the United Kingdom, Germany and the United States, have…
A great deal of solutions using new technologies have been released to help tackle the Covid-19 pandemic and a panel of international experts shared a few examples during the Barcelona Health Summit last October. Contact-tracing apps are an interesting option to manage a pandemic, but the creation process can take a long time and must meet several requirements, according to a Dutch official who…
Nearly a quarter of the world’s population may not have access to a covid-19 vaccine until at least 2022, warns a study published by The BMJ. A second study estimates that 3.7 billion adults worldwide are willing to have a covid-19 vaccine, highlighting the importance of designing fair and equitable strategies to ensure that supply can meet demand, especially in low and middle income countries.
An Artificial Intelligence test has been shown to be able to rapidly screen patients arriving in Emergency Departments for Covid-19, using clinical information routinely available within the first hour of coming to hospital. Results of the CURIAL study, published in The Lancet Digital Health, show that the AI test correctly predicted the Covid-19 status of 92.3% of patients coming to Emergency…
Scientists at UC Berkeley and Gladstone Institutes have developed a new CRISPR-based COVID-19 diagnostic test that, with the help of a smartphone camera, can provide a positive or negative result in 15 to 30 minutes.
A new class of epidemiological models based on alternative thinking about how contagions propagate, particularly in the early phases of a pandemic, provide a blueprint for more accurate epidemic modeling and improved disease spread predictions and responses, according to a study published recently in Scientific Reports by researchers at the University of California, Irvine and other institutions.
Healthcare workers are 7 times as likely to have severe Covid-19 infection as those with other types of ‘non-essential’ jobs, finds research focusing on the first UK-wide lockdown. And those with jobs in the social care and transport sectors are twice as likely to do so, emphasising the need to ensure that essential (key) workers are adequately protected against the infection, say the…
The U.S. Food and Drug Administration authorized the first diagnostic test for at home collection of patient samples to detect both Covid-19 and influenza A and B (flu). The FDA authorized Quest Diagnostics RC Covid-19 +Flu RT-PCR Test for prescription use with the Quest Diagnostics Self-Collection Kit for Covid-19 +Flu by individuals who are suspected of respiratory viral infection consistent…
The sudden spread of COVID-19 in early 2020 has considerably exacerbated the issue as it forced the closure of “non-essential” radiology activities while dramatically increasing the number of patients requiring a scan.
Researchers in Finland have developed a machine learning model that can help us treat cancer more effectively.
For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.
A panel of experts from the USA and China highlighted AI use in radiological workflow during the Covid pandemic and identified current pitfalls during the Hot Topic session at RSNA 2020. Radiologists from the USA prioritised Covid articles, delivered quick reviews, made all results open access, and helped organise a white paper from the Fleischner Society recognising recommendations for the role…
Covid-19 causes characteristic changes in lung tissue visible in CT scans and chest radiographs, known as “ground-glass” opacities. Imaging is now considered a valid alternative, possibly even superior to RT-PCR. ‘This sparked an international debate about the role of CT in the diagnostic work-up of Covid-19,’ said radiologist Professor Cornelia Schäfer-Prokop.
RSNA 2020: International experts showcased new studies on chest CT’s role in Covid-19 diagnosis and treatment. A staggering volume of work and has been produced on the pandemic this year, with an average 367 Covid-19 journal articles published per week, according to Michael Chung, Assistant professor of radiology at Icahn School of Medicine at Mount Sinai, NYC.
None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, researchers conclude after the analysis of virus genomes from over 46,000 people with COVID-19 from 99 countries.
A senior UK health figure has highlighted how contrasting leadership approaches are impacting the response to the global coronavirus crisis. Dr Clare Gerada also fears that response is affecting health professionals and leaders within the sector, with a significant rise numbers seeking help for mental health issues. Delivering the prestigious Sir Godfrey Hounsfield Lecture to the 2020 British…
According to Professor Fabian Bamberg, Medical Director at the Clinic for Diagnostic and Interventional Radiology at University Hospital Freiburg, Germany, ‘In recent years, cardiac CT has seen a mindboggling technological evolution.’ It is, he believes, a very robust procedure that allows the routine acquisition of high-resolution images with very few side effects.
In a virtual roundtable 5G discussion five healthcare IT experts, three senior executives from major USA medical centres and two consultants, discussed questions posed by members of the Healthcare Information and Management Systems Society (HIMSS).
Although the Covid-19 pandemic has put wind behind the sails of AI in healthcare, domain specific tools are needed to build and deploy AI and harness its power in data handling, training workflows and reproducibility of state-of-the-art approaches, according to Kimberly Powell, NVIDIA Vice President of Healthcare at the technology firm NVIDIA, presenter of a public address at RSNA 2020.
The coronavirus pandemic has had a severe impact on healthcare services but one area where that has been felt particularly deeply is with lung cancer screening. With sessions cancelled, treatment delays and social-distancing and safety requirements, many patients have been affected. However, as services begin to pick up again and lung cancer screening returns, three experts closely associated…
In the COVID-19 pandemic, 57 million people have already been infected worldwide. In the search for vaccines and therapies, a precise understanding of the virus, its mutations and transmission mechanisms is crucial.
In a new study, researchers performed a detailed imaging analysis to determine how the virus reprograms infected cells.
Germany’s lack of diagnostic ability led to significantly underestimation of its own as well as global Covid-19 infection levels during the first wave. Now, however, improved testing and diagnosis of the condition more realistically reveal nearer 20,000 new cases a day across the country, according to Professor Hendrik Streeck, one of the country’s leading virologists. Speaking at a virtual…
At Fraunhofer IZM, research is being conducted on durable microimplants that stimulate nerve cells electrically in a targeted manner and are even to be used to treat multiple sclerosis. Read more in the MEDICA magazine.
Re-starting the global economy for billions of people will depend on successfully overcoming logistical challenges in the ‘last mile’ of a COVID-19 vaccine’s journey to immunisation stations, according to a new report.
Overcrowding is a challenge that faces numerous hospitals across the UK. The burden of managing occupancy rates can immediately turn into a major issue that puts immense pressure on hospital staff, patients and their families alike. Studies show that when capacity rates increase above 92.5%, the death rate in hospitals can expand exponentially. It can represent one-in-seven mortalities amongst…
Digital epidemiology is on the frontline in the Covid-19 war, with innovative techniques used to observe and monitor this viral spread across populations. Its increasingly important role was outlined to a virtual session at Medica 2020 by theoretical biologist Professor Dirk Brockmann. In a keynote presentation ‘Perspective of digital epidemiology – opportunities, promises and challenges’,…
For the first time, an international research alliance has observed the RNA folding structures of the SARS-CoV2 genome with which the virus controls the infection process. This could not only lay the foundation for the targeted development of novel drugs for treating Covid-19, but also for occurrences of infection with new corona viruses that may develop in the future.
A new study suggests that individuals who have previously had COVID-19 are highly unlikely to contract the illness again, for at least six months following their first infection. The study, done as part of a major collaboration between the University of Oxford and Oxford University Hospitals (OUH) NHS Foundation Trust, was published as a pre-print.
For the first time in the history of MEDICA, the world-leading medical trade fair, and the industry’s number one platform for the suppliers of the medical technology industry, COMPAMED, held from 16 to 19 November 2020, took place entirely online due to the pandemic - but still won over their audiences due to their high degree of international resonance in this format too, as virtual.MEDICA and…
The Plasma Protein Therapeutics Association (PPTA) welcomes the European Commission’s publication of the Inception Impact Assessment (IIA) as a necessary step in the ongoing evaluation of the EU legislation on blood, tissues, and cells (BTC). Rightfully, the assessment underlines the need for timely action to decrease Europe’s reliance on third countries for plasma. The PPTA appeals to…
To support customers and clinicians and provide solutions for managing patients during the current global pandemic, Canon Medical Systems USA, Inc. is offering a resource to help them more effectively use its ultrasound systems for assessing and managing patients diagnosed with Covid-19.
Siemens Healthineers announced its SARS-CoV-2 IgG Antibody Test (sCOVG) has proven to measure neutralizing antibodies and has achieved CE Mark. The test is an enhanced version of the assay which became available globally this summer. It demonstrates the ability to detect neutralizing antibodies and reports quantitative results measuring the amount of neutralizing antibodies present in a patient's…
Since the Covid-19 epidemic took hold, the public has expected ‘unprecedented progress from the scientific community,’ observed Dan Shine, senior vice president and president of the analytical instruments division of Thermo Fisher Scientific Inc. ‘A deeper analysis of proteins is critical to understanding disease, including novel viruses. New instruments, software and workflows can power…
A UK biotech laboratory has used mass spectrometry in a new approach to coronavirus testing. MAP Sciences developed a gargle test, which collects samples from the back of the throat, and avoids the unpleasant sensation of the current PCR (polymerase chain reaction) swab tests. From there, the sample is tested for coronavirus using mass spectrometry (MS) with high levels of accuracy.
As COVID-19 spreads across the world, hospitals are utilizing disinfection robots to sanitize surfaces and minimize risk for their staff. Read on our partner site tectales.com about how some of those robots kill 99.99 percent of germs.
Experts have identified two distinct immunological and cellular profiles in the lungs of Covid-19 patients which they believe could help define treatment pathways. From some of the earliest Covid-19 autopsies conducted in Europe, Swiss-based researchers have performed integrative digital pathology and transcriptomic analyses of lung tissues of 16 coronavirus patients who died from respiratory…
In early 1990, at Analytica, in Munich, a young US-American researcher Kary B Mullis received the award for biochemical analytics for his 1983 invention: the polymerase chain reaction (PCR) – a success topped in 1993 by the Nobel Prize for chemistry. Mullis’ work revolutionised DNA copying, a process which, before PCR, had taken weeks. Whilst initially PCR was used to create digital…
For the first time in their history, the world-leading medical trade fair MEDICA and the international number one event for the medical manufacturing supply market, COMPAMED, will be held entirely online as virtual.MEDICA and virtual.COMPAMED from Monday, with around 1,400 exhibitors hailing from 56 countries. Throughout the four days of the trade fair (16 – 19 November 2020), international…
Wearable ultrasound sensors can help patients monitor their lung health from their own homes. The potential application of this technology were outlined in a session at MEDICA 2020.
Recent research in Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) has identified two enzymes that can detect Covid-19 RNA as simply as a pregnancy test Jesús Pla, an eminent microbiologist at the Complutense University in Madrid, explained in our exclusive interview. CRISPR technology could help alleviate workloads in packed hospitals and expand testing to primary care and…
EEG is used in cognitive research or to diagnose conditions like epilepsy and sleep disorders. However, EEG electrode caps are difficult to wear. Read in the MEDICA magazine about a viable alternative: measuring devices made of printed electronics.
Scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hours - read more in the MEDICA magazine.
Large proportions of patients can be safely triaged either to rule out discharge or rule in lifesaving management – if following the European Society of Cardiology (ESC) Guidelines Class I recommendation of two serial measurements of hs-cTnI on admission and after one hour, if there are assay specific cut off values for the 0/1 algorithms. The Pathfast hs-cTNI assay is an approved system to…
MEDICA in Düsseldorf is a world-leading platform for the medical technology business and the healthcare industry and has always been one of the places to be for the entire sector as it covers current digital health trends, innovative products and services for linking all of the major stakeholders in medical care. Consequently, digital health is a mainstay of virtual.MEDICA, which, due to the…
Ultrasound specialists at the Hainan Hospital of Chinese People’s Liberation Army General Hospital in Sanya and the Zhejiang Provincial People’s Hospital of Hangzhou successfully conducted robotic tele-ultrasound examinations over a 5G network of four patients with confirmed and suspected Covid-19. They were in Tongxiang and Wuhan, cities some 2600+ kilometres distant.
Measures to reduce the spread of Covid-19 through non-pharmaceutical interventions (NPIs) such as mask wearing and social distancing are a key tool in combatting the impact of the ongoing coronavirus pandemic. These actions also have greatly reduced incidence of many other diseases, including influenza and respiratory syncytial virus (RSV).
Beckman Coulter announced the launch of its Access SARS-CoV-2 Immunoglobulin M (IgM) assay in countries accepting the CE Mark. The new IgM antibody test demonstrated 99.9% specificity with 1,400 negative samples and 100% sensitivity at >18 days post symptom onset and post positive PCR. Beckman Coulter’s IgM assay is part of a full suite of testing solutions the company is developing to…
The accuracy of a rapid finger-prick antibody test for SARS-CoV-2, the virus responsible for covid-19 infection, may be considerably lower than previously suggested, finds a study published by The BMJ. The results suggest that if 10% of people given the test had previously been infected, around 1 in 5 positive test results would be incorrect (false positive results). These conclusions contrast…
Safety and protection for patients and healthcare professionals during routine procedures is imperative for Fujifilm, which it intends to pursue by constantly innovating its offering of accessories and instruments for endoscopy. The company announced the launch of the Mouthpiece “B1” incorporating a sponge rubber, a droplet reduction accessory, and a drape shield specifically created to catch…
Necessity is the mother of invention: While many companies have been hit hard by the coronavirus pandemic, some were able to find the hidden business opportunities. Read in the MEDICA magazine, how companies can benefit from the Covid-19 crisis.
The academic teaching Karlsruhe Hospital, at the University of Freiburg, is the largest hospital providing tertiary care in the Middle Upper Rhine Valley. Every year, 63,000 in-patients and 180,000 out-patients are treated in the 1,500-bed facility with 50 departments and 30 out-patient clinics. Inevitably, a hospital of this size has a central lab. We spoke with Dr Horst Mayer, managing senior…
An innovative nanoparticle vaccine candidate for the pandemic coronavirus produces virus-neutralizing antibodies in mice at levels ten-times greater than is seen in people who have recovered from COVID-19 infections. Designed by scientists at the University of Washington School of Medicine in Seattle, the vaccine candidate has been transferred to two companies for clinical development.
Asian ethnicity is strongly linked to COVID-related stroke, reveals an analysis of stroke centre activity in England and Scotland during the first wave of the coronavirus pandemic, and accepted for publication in the Journal of Neurology Neurosurgery & Psychiatry.
Why do most viral epidemics spread cyclically in autumn and winter in the globe's temperate regions? The answer is intimately related to our sun.
University of Pittsburgh School of Medicine scientists have discovered the fastest way to identify potent, neutralizing human monoclonal antibodies against SARS-CoV-2, the virus that causes COVID-19.
Russian tech company Connectome.ai is bringing its innovative Directiva.ai hand hygiene teaching and monitoring system to two major clinics owned by the European Medical Center group, the leading private healthcare provider in Moscow and the surrounding region.
This year, the International Day of Radiology is dedicated to all imaging professionals and their essential role in fighting the COVID-19 pandemic, making an indispensable contribution to the diagnosis and treatment of COVID-19 patients.
Specialists from the Department of Fundamental Medicine of Far Eastern Federal University (FEFU) with Russian and Japanese colleagues have probed into mechanisms of COVID-19 inside-the-body distribution linked to erythrocytes damaging.
A study conducted by Richard Vander Heide, MD, PhD, Professor and Director of Pathology Research at LSU Health New Orleans School of Medicine, and Marc Halushka, MD, PhD, Professor of Pathology at Johns Hopkins University School of Medicine, suggests myocarditis caused by COVID-19 may be a relatively rare occurrence.
Over 80 percent of 200 COVID-19 patients in a hospital in Spain have vitamin D deficiency, according to a new study.
Merck announced a collaboration with Mammoth Biosciences Inc. for the development, scale-up and commercial production of Mammoth’s CRISPR-based SARS CoV-2 diagnostic test.
This year, the MEDICA LABMED FORUM will offer a high-profile programme with top speakers which is free for registered online visitors.
Asymptomatic coronavirus sufferers appear to lose detectable antibodies sooner than people who have exhibited COVID-19 symptoms, according to one of the biggest studies of its kind in Britain published on Tuesday.
Research and innovation hub Imec announced that it has started developing a groundbreaking SARS-CoV-2 test. Unlike current approaches (using blood, saliva, or a nasopharyngeal swab), the new test will identify SARS-CoV-2 virus particles in a person’s exhaled breath. The solution promises the accurate identification of a contagious case in less than five minutes.
Researchers at Newcastle University are involved in a study to understand the risks of COVID-19 transmission on public transport and to identify the best measures to control it. Known as Project TRACK (Transport Risk Assessment for Covid Knowledge), the study will conduct fieldwork on buses and trains in London, Leeds and Newcastle, including the Metro system in Tyne and Wear.
‘Mini-lungs’ grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs. Writing in the journal Cell Stem Cell, the researchers detail the mechanisms underlying SARS-CoV-2 infection and the early innate immune response in the lungs.
Convalescent plasma shows limited effectiveness as a potential treatment for patients with COVID-19 to help them fight off the infection, finds a clinical trial from India published by The BMJ. The findings show that convalescent plasma fails to reduce mortality or stop progression to severe COVID-19.
Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe. Speaking before he delivered the prestigious Michel Clavel lecture to the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which was due to take place…
Vaccines are being hailed as the solution to the COVID-19 pandemic, but the vaccine trials currently underway are not designed to tell us if they will save lives, reports Peter Doshi, Associate Editor at The BMJ. Several COVID-19 vaccine trials are now in their most advanced (phase 3) stage, but what will it mean exactly when a vaccine is declared “effective”? Many may assume that successful…
The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior. Neuropilin-1 is localized in the respiratory and olfactory epithelia, which could be a strategically important localization to contribute to…
A new risk tool, developed by UK researchers to predict a person’s risk of being admitted to hospital and dying from COVID-19 has been published by The BMJ. With cases increasing in the UK and elsewhere, and winter approaching, there is an urgent need for reliable models that predict the likely course of COVID-19, to support decisions about shielding, hospital admission, treatment, and…
The present Coronavirus pandemic with all its effects on society – both health and economic – highlights the urgency of developing new therapies for COVID-19 treatment. At the same time, it demonstrates the necessity to become well prepared for new virus infections we may be facing in the future. To help control the current pandemic and brace for novel pathogens that may cause future…
As President Trump claims that he is immune to COVID-19 and isolated reports emerge of reinfection, what is the truth about immunity to COVID-19? To date, there have been six published cases of COVID-19 reinfection, with various other unverified accounts from around the world. Although this is a comparably small fraction of the millions of people known to have been infected, should we be…
Innate immunity is the fastest-acting component of the immune system, but so far little is known about its role during infection with SARS-CoV-2. A few hours after an infection, the body emits an alarm signal, interferon, enabling cells that have not yet been infected to produce antiviral proteins. This phenomenon occurs well before the production of neutralizing antibodies. Scientists from the…
Researchers around the world can tap into a new inter-disciplinary online database of COVID-19 research, allowing them to search for new partners, resources and funding to boost the global battle against the virus.
Although uncommon, sudden permanent hearing loss seems to be linked to COVID-19 infection in some people, warn doctors, reporting the first UK case in the journal BMJ Case Reports. Awareness of this possible side effect is important, because a prompt course of steroid treatment can reverse this disabling condition, they emphasise. Sudden hearing loss is frequently seen by ear, nose and throat…
Researchers at CSIRO, Australia's national science agency, have found that SARS-CoV-2, the virus responsible for COVID-19, can survive for up to 28 days on common surfaces including banknotes, glass – such as that found on mobile phone screens - and stainless steel.
It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans. Even decades of research have only produced a few standardized vaccines and strategies for treatment to combat just a small number of viruses. Nor…
The COVID-19 pandemic has impacted virtually every aspect of cancer care and research– from introducing new risks for cancer patients to disrupting the delivery of cancer treatment and the continuity of cancer research.
Scientists at EPFL are using technology to better understand how coronavirus causes blood clots in some patients. They have developed a simplified model of a lung that lets them observe, for the first time, how the virus attacks the cells lining blood vessels.
Setting up ‘COVID-19 free’ hospital areas for surgical patients could save lives during the second wave of the pandemic – reducing the risk of death from lung infections associated with coronavirus, a new global study reveals. Researchers working together in Brazil and beyond found that that patients who had their operation and hospital care in ‘COVID-19 free’ areas had better outcomes.…
Our immune system can efficiently fend off viral diseases. Two types of immune cells play an important role in this process: The T-cells, which firstly can directly destroy virus-infected cells and secondly enable the formation of efficient, virus-neutralizing antibodies by B-cells. These two cell types also play a crucial role in the immune defense against SARS-CoV-2 infection. Whereas antibody…
With COVID-19 testing an important part of controlling the spread of the virus, finding an effective software system to manage the testing process and collate the results, on a national level and individually within businesses, hospitals, care-homes and schools etc., is essential. Thomson Screening developed SchoolScreener Imms in order to manage health testing within schools, but with the…
The COVID-19 pandemic has created a flood of potentially substandard research amid the rush to publish, with a string of papers retracted or under a cloud and a surge in submissions to pre-print servers where fewer quality checks are made, a leading ethicist has warned in the Journal of Medical Ethics. This has implications for patients, clinicians, and potentially government policy, says…
A new mobile app has made it possible to analyse the genome of the SARS-CoV-2 virus on a smartphone in less than half an hour.
Ventilation systems in many modern office buildings, which are designed to keep temperatures comfortable and increase energy efficiency, may increase the risk of exposure to the coronavirus, particularly during the coming winter, according to new research.
The Society for Cardiovascular Magnetic Resonance (SCMR), a Society dedicated to improving cardiovascular health by advancing the field of cardiovascular magnetic resonance (CMR), has released a formal statement supporting and explaining their position on the use of CMR in COVID-19 patients. The topic has led to debate among medical professionals, especially those in the cardiology specialty.
An analysis by ECRI, the U.S.’s largest patient safety organization, shows that up to 70 percent of KN95 masks it tested do not meet its standards for effectiveness, raising risks of contracting Covid-19 for care providers and patients at hospitals and other healthcare organizations that imported masks from China.
Adequate levels of vitamin D reduces complications and deaths among COVID-19 patients, reveals new research performed at the Boston University School of Medicine. Hospitalized COVID-19 patients who were vitamin D sufficient, with a blood level of 25-hydroxyvitamin D of at least 30 ng/mL (a measure of vitamin D status), had a significant decreased risk for adverse clinical outcomes including…
As COVID-19 infections begin to rise again, a novel testing strategy proposed by researchers at the University of Oxford at the start of the pandemic has become urgent once again. The strategy aims to bring the virus’s reproduction number (‘R’) down to below 1, by concentrating testing resources on particular groups in the population that are most likely to spread the infection to others,…
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination. In this process, they have also discovered that some SARS-CoV-2 antibodies bind to tissue samples from various organs, which could potentially…
Surface disinfection has proved an effective method to control Covid-19 infection, as virologists from the Ruhr University Bochum (RUB) have shown. However, an effective disinfection strategy against Coronavirus must consider various factors, says Professor Eike Steinmann, head of the Department of Molecular and Medical Virology at the RUB.
Scientists have unearthed a possible link between the severity of COVID-19 and air quality. The preliminary study – looking at whether areas with higher levels of air pollutants in England are associated with a larger number of cases/deaths from COVID-19 – was conducted by a team from the University of Cambridge. Aware of the effects that air pollutants have on human health – and that…
More than 32,000 people from over 160 countries registered for The Alzheimer’s Association International Conference (AAIC 2020) in July. This largest and most influential international conference on dementia science had to be held virtually this year, when important highlights were aired. The ability to identify individuals at high risk of developing Alzheimer’s Disease (AD), or at early…
People with ‘silent’ COVID-19 infection have as much coronavirus in their noses and throats as those with symptoms, reveals research published online in the journal Thorax. Given how many of these people there are---a fifth of those infected, the study findings show--they may have a key role in driving the spread of COVID-19, warn the researchers, who go on to suggest that this warrants…
A recent preprint study in France underpins the debate on whether lung ultrasound (LUS) should be used to triage COVID-19 patients better at the hospital as well as in primary care. The eChoVid study, published as a preliminary report of work on medTrix, shows that LUS enables identification of lung lesions as well as chest CT in COVID-19 patients. A team of French researchers compared routinely…
There are many reasons why for some patients a visit to the doctor’s office is difficult or well-nigh impossible – limited mobility after surgery, old age, or a handicap. For others, particularly in rural areas, the doctor is often far away and/or difficult to reach due to poor public transport. In times of corona, another important issue emerged: infection protection.
Ultrasound could become the prime modality in emergency settings for tracking disease progression in COVID-19 patients. While chest CT has held a key diagnostic role thus far, many experts now advocate the benefits of ultrasound within the context of the coronavirus epidemic. Dr Rachel Liu, who recently led a high-profile panel discussion with experts from the USA and areas of Europe with high…
Researchers predict that COVID-19 will likely become seasonal, waning in the summer and prevalent in the winter. But, only once herd immunity is achieved through natural infection or vaccinations. Until then, COVID-19 will be here year-round.
Medica 2020 and Compamed 2020, the information and communication platforms for the medical technology industry and supplier industry for the medical technology industry, will take place entirely online from 16 to 19 November. Within the framework of 'virtual.Medica' and 'virtual.Compamed', decision-makers from all sectors of the healthcare industry can then expect a comprehensive range of…
Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the coronavirus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against the coronavirus.
The increased Covid-19 risk to cardiac patients was discussed during an online presentation at ECR 2020. Focusing on the prevalence of pulmonary embolism in Covid-19 patients, Dr Karl-Friedrich Kreitner, Professor of Radiology at the Department of Diagnostic and Interventional Radiology at the Johannes-Gutenberg University in Mainz, Germany, discussed hypotheses which can explain cardiac…
Artificial Intelligence (AI) has, for the first time, measured blood flow to the heart to help predict which patients may suffer myocardial infarction or stroke. A research team at University College London and Barts Health NHS Trust and the National Institutes for Health (NIH) in the USA – are optimistic that AI analysis of perfusion maps will be a reliable, convenient and detailed new…
Carestream Health has entered the personal protection equipment (PPE) market with the launch of the CARESTREAM Shield, solving problems of discomfort and difficulty of use commonly associated with personal face shields.
Contrary to expectations, the risk of COVID-19 infection among hospital staff at the height of the coronavirus pandemic was lowest among intensive care clinicians, reveals a study of one major UK medical centre, published in the journal Thorax.
An easy-to-use score for predicting risk of death in adult patients admitted to hospital with covid-19 outperforms existing scores and can be used to support treatment decisions, finds a study published by The BMJ today.
Rhinovirus, the most frequent cause of common colds, can prevent the flu virus from infecting airways by jumpstarting the body's antiviral defenses.
COVID-19 patients can suffer long-term lung and heart damage but, for many, this tends to improve over time, according to the first, prospective follow-up of patients infected with the coronavirus, presented at the European Respiratory Society International Congress. [1]
The healthcare system of Taiwan, renowned for its ability to tackle challenges, has held up very well during the COVID-19 pandemic. To underline the nation’s role as a healthcare innovator, the Taiwan External Trade Development Council (TAITRA) presented several of the most promising companies and their products in an exclusive webinar. The event showcased cutting-edge technologies as well as…
An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases (DZNE) and Cornell University in the US have investigated cellular factors that could be significant for an infection. To this end, they analysed the activity of 28 specific genes in a wide range of human tissues.
Generous donations made by companies and individuals funded seven state-of-the-art isolation pods for COVID-19 patient transport in Greece. The Greek ambulance service, EKAB, acquired seven top modern isolation pods, known as EpiShuttle, from the generous donations made to them.
As COVID-19 continues to spread, bottlenecks in supplies and laboratory personnel have led to long waiting times for results in some areas. In a new study, University of Illinois, Urbana-Champaign researchers have demonstrated a prototype of a rapid COVID-19 molecular test and a simple-to-use, portable instrument for reading the results with a smartphone in 30 minutes, which could enable…
Fujitsu and Tokyo Shinagawa Hospital today announced the launch of a joint R&D project for AI technology to support diagnostic imaging via chest CT (Computed Tomography), which represents a promising candidate for the effective diagnosis of COVID-19 pneumonia.
Heart patients hospitalised with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), according to the BRACE CORONA trial presented in a Hot Line session today at ESC Congress 2020.(1)
Taiwan has won global praise for its rapid pandemic response and precautionary measures taken to contain the coronavirus (COVID-19) pandemic that emerged earlier this year. This success is testament to Taiwan’s highly efficient public health and medical system, and the excellent quality of MIT (made in Taiwan) products. Medical Taiwan, which takes place from October 15 to 17, 2020 at Taipei…
Due to compromised immune systems cancer patients are at higher risk of contracting infections. How does cancer impact on patients who also contract Covid-19? To collect this data, four cancer registries, one in the EU, one in the UK, two in the USA, have been established. The first large, multi-institution study of the impact of Covid-19 was conducted in Wuhan, China, and presented at the…
More than 73,000 users collaborate on new online platform set up by the European Open Science Cloud Initiative, where scientists share COVID-19 data and accelerate our understanding of the virus to help develop treatments and vaccines quicker.
A Hong Kong man who recovered from COVID-19 was infected again four-and-a-half months later in the first documented instance of human re-infection, researchers at the University of Hong Kong reported.
Sending a “selfie” to the doctor could be a cheap and simple way of detecting heart disease, according to the authors of a new study. The study is the first to show that it’s possible to use a deep learning computer algorithm to detect coronary artery disease (CAD) by analysing four photographs of a person’s face. Although the algorithm needs to be developed further and tested in larger…
The airborne transmission of the coronavirus SARS-CoV-2 via aerosol particles in indoor environment seems to be strongly influenced by relative humidity. This is the conclusion drawn by researchers from the Leibniz Institute for Tropospheric Research (TROPOS) in Leipzig and the CSIR National Physical Laboratory in New Delhi from the analysis of 10 most relevant international studies on the…
In the most comprehensive study of COVID-19 pediatric patients to date, Massachusetts General Hospital (MGH) and Mass General Hospital for Children (MGHfC) researchers provide critical data showing that children play a larger role in the community spread of COVID-19 than previously thought. In a study of 192 children ages 0-22, 49 children tested positive for SARS-CoV-2, and an additional 18…
Researchers studying tissue removed from patients noses during surgery believe they may have discovered the reason why so many people with COVID-19 lose their sense of smell, even when they have no other symptoms. In their experiments they found extremely high levels of angiotensin converting enzyme II (ACE-2) only in the area of the nose responsible for smelling. This Enzyme is thought to be the…
Medical device approved 3-D printers are producing clinically safe and effective nasopharyngeal swabs for COVID-19 testing. A nasal swab may seem rudimentary, but is essential for testing COVID-19. Diagnostic test kits and components – nasal swabs, collection vials, and chemical reagents – have been in short supply worldwide, especially in March. Ironically, nasopharyngeal swabs are…
Value-based healthcare is gaining momentum and radiologists must increasingly show their contribution in improving patient care. Artificial intelligence (AI) can help them to do so and brings a series of new opportunities, according to Charles E Kahn, Professor and Vice Chairman of Radiology at the University of Pennsylvania, speaking at a meeting in Madrid in January. AI can do a lot to improve…
Northwestern University researchers have uncovered a new vulnerability in the novel coronavirus’ infamous spike protein — illuminating a relatively simple, potential treatment pathway. The spike protein contains the virus’ binding site, which adheres to host cells and enables the virus to enter and infect the body. Using nanometer-level simulations, the researchers discovered a positively…
The Center for Noise and Vibration Control at the Korea Advanced Institute of Science and Technology (KAIST) announced that their coughing detection camera recognizes where coughing happens, visualizing the locations. The resulting cough recognition camera can track and record information about the person who coughed, their location, and the number of coughs on a real-time basis. Professor…
Researchers from Eindhoven University of Technology (TU/e) and the Catharina Hospital in Eindhoven have developed a new algorithm for the rapid screening for COVID-19. The software is intended for use in Emergency Rooms (ER), to quickly exclude the presence of corona in incoming patients. As a result, doctors need to conduct fewer standard coronavirus tests, increasing efficiency. The quick scan…
Researchers at the University of Notre Dame are developing a new technique using artificial intelligence (AI) that would improve CT screening to more quickly identify patients with the coronavirus. The new technique will reduce the burden on the radiologists tasked with screening each image. Testing challenges have led to an influx of patients hospitalized with COVID-19 requiring CT scans which…
A rather unique trial in the UK currently explores the capability of dogs to detect coronavirus infections in humans with their highly sensitive noses. The researchers are asking people in England for help with the trial. Led by the ARCTEC team at the London School of Hygiene & Tropical Medicine (LSHTM) in collaboration with the charity Medical Detection Dogs and Durham University, the trial…
As the COVID-19 pandemic continues to claim lives around the world, much research has focused on the immune system’s role in patients who become seriously ill. A popular theory has it that the immune system gets so revved up fighting the virus that, after several days, it produces a so-called cytokine storm that results in potentially fatal organ damage, particularly to the lungs.
The SARS CoV-2 virus which causes COVID-19 may have been named prematurely. As more has become known about the infection, the severe disease does not appear to be a respiratory syndrome at all. Patients who only have a respiratory illness tend not to have a severe condition, while patients who develop a severe condition tend to have non-respiratory conditions, primarily thrombotic or hyper-immune…
Genes that are thought to play a role in how the SARS-CoV-2 virus infects our cells have been found to be active in embryos as early as during the second week of pregnancy, say scientists at the University of Cambridge and the California Institute of Technology (Caltech). The researchers say this could mean embryos are susceptible to COVID-19 if the mother gets sick, potentially affecting the…
Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction – rather, the immune response is caught in a continuous loop of activation and inhibition.
The Covid-19 pandemic has led to a significant increase in video visits between patients and their doctors, but for many older adults, the shift has cut them off from care, rather than connecting them. A study by researchers at the University of California San Francisco has found that more than a third of adults over age 65 face potential difficulties seeing their doctor via telemedicine, with…
As the corona pandemic continues, mechanical ventilators are vital for the survival of COVID-19 patients who cannot breathe on their own. One of the major challenges is tracking and controlling the pressure of the ventilators, to ensure patients get exactly the amount of air they need. Researchers at the Eindhoven University of Technology (TU/e) have developed a technique based on self-learning…
Injuries in the nervous system of patients with severe COVID-19 are revealed by magnetic resonance imaging (MRI) and computed tomography (CT). In a study of 185 patients, researchers at Karolinska Institutet (KI) and Karolinska University Hospital show an affection of microscopic blood vessels and inflammation in the brain, meninges and nerves. The results are published in Radiology.
A significant number of patients reported a deterioration in their hearing when questioned eight weeks after discharge from a hospital admission for COVID-19, according to University of Manchester audiologists, in a study supported by the NIHR Manchester Biomedical Research Centre (BRC). One hundred and twenty one of the adults admitted to Wythenshawe Hospital, part of Manchester University NHS…
Approximately one fifth of COVID-19 patients admitted to German hospitals between the end of February and mid-April died. For patients receiving ventilation, the mortality rate was 53%. For those not receiving ventilation, the rate was significantly lower at 16%. 17% of all patients were ventilated during this period. These are the main results of an analysis by WIdO, the research institute of…
As the COVID-19 pandemic continues, finding a treatment to effectively fight the disease remains a major research challenge. Researchers from Inserm, CNRS, Université Claude Bernard Lyon 1 and ENS Lyon within the International Center for Infectious Disease Research (CIRI) have developed a unique strategy for selection, evaluation and repositioning of drugs already on the market to assess their…
Existing limited evidence suggests that wearing face coverings to protect against COVID-19 does not lead to a false sense of security and is unlikely to increase the risk of infection through wearers foregoing other behaviours such as good hand hygiene, say researchers from the University of Cambridge and King’s College London.
Airborne and potentially deadly, the virus that causes COVID-19 can only be studied safely under high-level biosafety conditions. Scientists handling the infectious virus must wear full-body biohazard suits with pressurized respirators, and work inside laboratories with multiple containment levels and specialized ventilation systems. While necessary to protect laboratory workers, these safety…
Chemical binding company Affix Labs has created the first long-lasting surface treatment proven to kill COVID-19. Si-Quat combines a safe and well-established disinfectant and a proprietary chemical binding technique, so that the active ingredient can kill viruses, including SARS-CoV-2. Testing at Portugal’s Biochemistry Institute at the University of Lisbon proves that Si-Quat effectively…
A team of scientists at Oxford University’s Jenner Institute and Oxford Vaccine Group has taken the next step towards the discovery of a safe, effective and accessible vaccine against coronavirus. The results of the Phase I/II trial published in the scientific journal, The Lancet, indicate no early safety concerns and induces strong immune responses in both parts of the immune system.
Although its name is relatively unspecific and indeed opaque, the Nonstructural Protein 1 (Nsp1) encoded by the coronavirus SARS-CoV-2, which is responsible for the current pandemic, has now been shown to have a devastating effect on host cells. Nsp1 is in fact one of the central weapons used by the virus to ensure its own replication and propagation in human hosts. Nsp1 was identified as a…
The T cells, along with antibodies, are an integral part of the human immune response against viral infections due to their ability to directly target and kill infected cells. A Singapore study has uncovered the presence of virus-specific T cell immunity in people who recovered from COVID-19 and SARS, as well as some healthy study subjects who had never been infected by either virus.
Frost & Sullivan’s recent analysis, Post-Pandemic Global Healthcare Market Outlook, 2020, forecasts that 2020 will be an unforgiving but transformational year for the healthcare industry. As the world grapples with a global emergency caused by the COVID-19 pandemic, the healthcare industry is expected to witness a drop in growth from 5.3% to 0.6% in 2020, with revenues remaining below the…
There are major complications from COVID-19 – ARDS, pulmonary embolism and neurological – that imaging can help detect, manage and/or follow up in the long term, radiologists from France and the UK explained during a recent ESR Connect session. ARDS is the most dreaded complication and the number one morbidity in COVID-19 patients. The incidence was up to 30% of patients in initial reports.…
Which patient will develop a severe form of COVID-19? This is an essential question which must be answered in order to improve the individual management and the prognosis of these patients. In a publication in the journal Science, teams from the Assistance publique – Hôpitaux de Paris (AP-HP), Inserm, Université de Paris, Institut Pasteur and Institut Imagine describe a unique and unexpected…
Physical distancing measures, such as closing schools, workplaces, and public transport, and restricting mass gatherings, are associated with a meaningful reduction in new COVID-19 cases, finds a study published by The BMJ. The data, gathered from 149 countries and regions, also show that implementing lockdown restrictions earlier was associated with a greater reduction in new cases. “These…
Despite its proximity to China, Taiwan contained COVID-19 successfully, without a lockdown or movement restriction measures introduced elsewhere. With few new cases reported, life almost returned to normal. Behind the scenes, however, efforts have continued to maintain that positive situation.
The critical role of radiographers in the coronavirus epidemic was highlighted in the final episode of the ESR Connect series of webcasts, ‘Radiology fighting COVID-19’. Three European speakers in the session ‘Radiologists & Radiographers: Lessons learned from the pandemic’ (chaired by Helmut Prosch, Professor of Radiology at the Medical University Vienna), discussed their coronavirus…
The coronavirus pandemic created unprecedented upheaval and challenges within health systems, economies, and society. In hospitals, new ways of working had to evolve. Social distancing led to virtual consultations and teleradiology has found an added dimension. We asked three radiologists about the relevance of teleradiology during the epidemic, and what the future holds.
EKF Diagnostics, the global in vitro diagnostics company, announces that it has added a novel viral transport media for the safe sample handling and testing of multiple infectious diseases from a single swab to its product range.
Half of COVID-19 patients who received a heart scan in hospital showed abnormalities in heart function, according to new research funded by the British Heart Foundation (BHF). The study, published in the European Heart Journal - Cardiovascular Imaging, found that around one in seven showed severe abnormalities likely to have a major effect on their survival and recovery. It also showed that one…
Department B for Internal Medicine of the University Medical Center Greifswald successfully used, within an international multi-center trial, a special diaphragmatic stimulation therapy to treat a COVID-19 patient as the first clinical site in Europe. "The first patient treated in this trial happened to be a woman who survived COVID-19, but was not able to be weaned from mechanical…
In the course of the corona pandemic, hospitals and clinics are facing a serious challenge, as staff and patients are at increased risk of infection. Fever screenings are increasingly being carried out at entrances of healthcare facilities to identify persons with symptoms. Temperature checks are already part of daily operations at many airports.
While scientists recently confirmed the crucial role contact-tracing apps play in containing the COVID-19 pandemic, politicians are exploring which app architecture offers better privacy protection. However, there is no doubt that in Western countries such an entirely voluntary app can only be successful if the population at large supports it.
Nanoelectronics and digital technologies R&D and innovation hub Imec recently received NASA funding to test a new technology in a gravity-free environment. Eventually, this will enable astronauts to perform blood tests to monitor their health. We discussed the project and technology with Nicolas Vergauwe, CEO of miDiagnostics, the Leuven firm that developed the diagnostic device, and Susana B…
It remains one of the key questions of the current corona pandemic: Why do people infected with SARS-CoV-2 experience varying degrees of COVID-19, the disease which it triggers? Researchers, led by Professor Mascha Binder from University Hospital Halle (Saale), have investigated more than 14 million receptor sequences of B and T cells, i.e. immune cells, obtained from blood samples of COVID-19…
The COVID-19 pandemic has affected children with direct impacts of the infection as well as on them leading normal lives. Schooling, play and vaccinations are among issues that can affect children’s health. Delay in taking paediatric patients to the emergency room (ER) has also had a negative impact, for example late treatment of acute appendicitis. Two experts from Spain tackled these topics…
Coupling function with fashion, cloth and home-sewn face masks are available in a variety of forms and fabrics. While experts underscore that wearing a mask is effective in helping to prevent the spread of COVID-19, not all masks — or the materials with which they’re made — contain virus particles equally. In a new video, University of Wisconsin–Madison engineer Scott Sanders demonstrates…
Researchers have developed a human cell ‘membrane on a chip’ that allows continuous monitoring of how drugs and infectious agents interact with our cells, and may soon be used to test potential drug candidates for COVID-19. The researchers, from the University of Cambridge, Cornell University and Stanford University, say their device could mimic any cell type - bacterial, human or even the…
It's intuitive and scientifically shown that wearing a face covering can help reduce the spread of the novel coronavirus that causes COVID-19. But not all masks are created equal, according to new University of Arizona-led research. Amanda Wilson, an environmental health sciences doctoral candidate in the Department of Community, Environment and Policy in the Mel and Enid Zuckerman College of…
New research from Karolinska Institutet and Karolinska University Hospital shows that many people with mild or asymptomatic COVID-19 demonstrate so-called T-cell-mediated immunity to the new coronavirus, even if they have not tested positively for antibodies. According to the researchers, this means that public immunity is probably higher than antibody tests suggest. The article is freely…
A plea issued by 239 scientists from around the world to recognise and mitigate airborne transmission of COVID-19 addressed to international health authorities is published in the journal Clinical Infectious Diseases. Led by internationally recognised air quality and health expert Professor Lidia Morawska from Queensland University of Technology (QUT), the appeal is to address the overwhelming…
Artificial Intelligence is an essential tool for the healthcare operators on the front line in the fight against the Coronavirus pandemic. ASST Vimercate Hospital chose and implemented in the midst of the COVID-19 emergency REiLI, Fujifilm Medical Systems’ Artificial Intelligence.
How high is the risk that aerosol transmission during choral singing could cause infection with the coronavirus? After occurrences of infection among choirs in the USA and Germany, Bavarian Broadcasting carried out a complex series of experiments for its musical ensembles in conjunction with the LMU University Hospital Munich and the Universitätsklinikum Erlangen (FAU).
Major weaknesses exist in the evidence base for COVID-19 antibody tests, finds a review of the latest research published by The BMJ. The evidence is particularly weak for point-of-care tests (performed directly with a patient, outside of a laboratory) and does not support their continued use, say the researchers. Serological tests to detect antibodies against COVID-19 could improve diagnosis and…
An overactive defense response may lead to increased blood clotting, disease severity, and death from COVID-19. A phenomenon called NETosi is part of an immune response that becomes increasingly hyperactive in people on ventilators and people who die from the disease.
Scientists have found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as “mini-brains” can be infected by the SARS-CoV-2 virus that causes COVID-19.
Beckman Coulter announced that its Access SARS-CoV-2 IgG assay has received Emergency Use Authorization (EUA) from the U.S. Food & Drug Administration (FDA). Beckman Coulter has already shipped tests to more than 400 hospitals, clinics and diagnostics laboratories in the U.S., and has begun distribution of the new antibody test globally to countries that accept the FDA EUA and CE Mark. The…
In the world of laboratory diagnostics, ‘Abbott’ is a household name. Few people however are aware of the fact that the company, headquartered in Illinois, USA, is also leading in other fields. A number of innovations in cardiac and vascular diagnostics and therapy might soon put Abbott in the limelight. Dr Angela Germer, Regional Director DACH, and Volker Keller, Head of Marketing DACH,…
A group of senior clinical academics and physicians are concerned about the rapid roll out of COVID-19 antibody testing in England and are publicly questioning how good the tests are - or even what they mean. In a letter to The BMJ, they argue that there is currently no valid clinical reason for large scale testing, test performance has not yet been adequately assessed, and testing risks…
Infection with the novel coronavirus SARS-CoV-2 follows a highly variable course: some of those infected do not even notice it, while others become so seriously ill that their lives are placed at risk. Scientists from the Berlin Institute of Health (BIH) and Charité – Universitätsmedizin Berlin and their colleagues from Leipzig and Heidelberg have now discovered that the immune system has a…
When infected by the new coronavirus, women may mount a more potent adaptive immune response than do men, a new study suggests. By comparison, the male immune response appears to progress less effectively, fostering inflammation that’s harmful to the body. This study is the first to delve into sex differences in how the immune system defends itself against the virus SARS-CoV-2. It could help…
The coronavirus crisis has accelerated the use of telemedicine in Spain with an increase in virtual consultation and positive impact on workflow. The challenge will be to make these changes permanent, according to a panel of experts who took part in a conference last June in Barcelona. Spanish patients and healthcare professionals have widely accepted virtual consultation as a new alternative to…
In many areas of our daily life, plastic is seen in a negative light. However, the ongoing SARS CoV-2 pandemic has profoundly changed our society with intensive efforts being made to find a way out of the crisis.
To develop and manufacture COVID-19 test kits in massive quantities was not part of their 2020 business plans. Yet, as the epidemic evolved into a global pandemic, the urgent need for diagnostic and antibody SARS-CoV-2 test kits triggered an unprecedented scramble among medical manufacturers.
Voice analysis by a smartphone app identifies lung congestion in heart failure patients, allowing early intervention before their condition deteriorates. The small study is presented on HFA Discoveries, a scientific platform of the European Society of Cardiology (ESC). “Speech is personal and as such, very small changes (related to the same person) can be detected – for example, the ability…
Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.
A standard drug for the treatment of depression might also be effective against Covid-19, a new study by Würzburg scientists shows which has been published on a preprint server
Researchers in the UK have shown that a widely available drug reduces death in hospitalised patients with severe respiratory complications of COVID-19.
A Danish pipetting robot is automating Covid testing processes in hospitals around Europe. The robot, called flowbot ONE, significantly reduces the time it takes for laboratories to produce results for patients to tell them whether they are infected with Covid-19.
In the hustle and bustle of a hospital, properly disinfecting all surfaces in a patient room can be a challenging and time-consuming task. Now, in times of the coronavirus pandemic, it can also be life-threatening. To minimize the risk for their staff, hospitals are utilizing disinfection robots to sanitize surfaces and rooms.
A new diagnostic test can detect the RNA of SARS-CoV-2, the virus that causes COVID-19, in urine, blood, saliva or mouth swab samples in just 30 to 45 minutes, according to a new study in the open-access journal PLOS ONE by Laura Lamb of the Beaumont Health System, Michigan, USA, and colleagues.
Researchers from Freie Universität Berlin at the Institute for Animal and Environmental Hygiene and the Institut für Textiltechnik (ITA) of RWTH Aachen University are collaborating on the topic of alternative personal protection equipment. The testing was conducted in the context of the EIT Health Project ViruShield, supported by the European Union, with the objective to discover alternative…
Population-wide use of facemasks keeps the coronavirus ‘reproduction number’ under 1.0, and prevents further waves of the virus when combined with lockdowns, a modelling study led by the University of Cambridge suggests. The research suggests that lockdowns alone will not stop the resurgence of SARS-CoV-2, and that even homemade masks with limited effectiveness can dramatically reduce…
Despite being at high risk of exposure to COVID-19, frontline healthcare professionals who were appropriately protected did not contract infection or develop protective immunity against the virus, finds a study from China published by The BMJ.
Early data from a clinical study suggest that blocking the Bruton tyrosine kinase (BTK) protein provided clinical benefit to a small group of patients with severe COVID-19. Researchers observed that the off-label use of the cancer drug acalabrutinib, a BTK inhibitor that is approved to treat several blood cancers, was associated with reduced respiratory distress and a reduction in the overactive…
New research suggests that cigarette smoke spurs the lungs to make more ACE2 (angiotensin-converting enzyme 2), the protein that the coronavirus responsible for COVID-19 grabs and uses to enter human cells. The findings, reported in the journal Developmental Cell, may explain why smokers appear to be particularly vulnerable to severe infections. The analysis also indicates that the change is…
Cloud computing isn’t exactly a new concept in the healthcare industry. Its benefits have become increasingly well-known across the sector and, without it, we wouldn’t have many health-related services that both healthcare professionals and patients now rely on. It’s no surprise then that the European healthcare cloud computing market is expected to be worth around £44 billion by 2025.…
Patients with raised blood pressure have a two-fold increased risk of dying from the coronavirus COVID-19 compared to patients without high blood pressure, according to new research published in the European Heart Journal. In addition, the study found that patients with high blood pressure who were not taking medication to control the condition were at even greater risk of dying from COVID-19.
Diagnostic imaging examinations and radiology departments have been essential in the care of the millions of COVID-19 patients. As the virus abates, how should radiology departments return to “normal” operations? The American College of Radiology (ACR) and the Radiological Society of North America (RSNA) have published recommendations and guidelines.
The COVID-19 pandemic has affected virtually every aspect of healthcare provision - cancer care is no exception. In fact, during the pandemic, patients with cancer represent a high-risk group. Recent studies estimate that delays in cancer diagnosis and treatment will increase the indirect death toll of COVID-19 by several thousands in the coming years.
Researchers at the Francis Crick Institute and Charité – Universitätsmedizin Berlin have identified 27 protein biomarkers that could be used to predict whether a patient with COVID-19 is likely to become severely ill with the disease. People infected with SARS-CoV-2, the virus which causes COVID-19, respond differently. Some do not develop any symptoms, some need to be hospitalised and, for…
University of Melbourne researchers are finding ways to beat dangerous superbugs with ‘resistance resistant’ antibiotics, and it could help in the fight against coronavirus (COVID-19) complications. As bacteria evolve, they develop strategies that undermine antibiotics and morph into ‘superbugs’ that can resist most available treatments and cause potentially lethal infections. The…
Preventing airborne transmission of COVID-19 should be the next front of the battle against the virus, argue experts from the University of Surrey. In a study published by the City and Environment Interaction journal, scientists from Surrey’s Global Centre for Clean Air Research (GCARE), together with partners from Australia’s Queensland University and Technology, argue that the lack of…
The first round of results from an immunological study of 149 people who have recovered from COVID-19 show that although the amount of antibodies they generated varies widely, most individuals had generated at least some that were intrinsically capable of neutralizing the SARS-CoV-2 virus. Antibodies vary widely in their efficacy. While many may latch on to the virus, only some are truly…
Early results from a study by researchers at Swansea University and The University of Manchester shows people are torn over whether they will use the COVID-19 contact tracing smartphone app planned for release in the UK. The study finds: Only one-third of people taking part said they will be downloading the app, with the rest either saying they will not be downloading it or are not yet sure;…
A self-disinfecting reusable protective face mask was developed at the Israel Institute of Technology (Technion) faculty of Materials Science and Engineering. The disinfection process occurs when a layer of carbon fibers in the mask is heated using a low current source, such as an electric mobile phone charger, the developers state. A patent application for this invention has been submitted in…
The prevalence of ‘silent’ symptomless COVID-19 infection may be much higher than thought, reveals a study charting the enforced isolation of cruise ship passengers during the current pandemic, and published online in the journal Thorax. More than eight out of 10 of passengers and crew who tested positive for the infection had no symptoms. This has implications for the easing of lockdown…
Siemens Healthineers announced today that it is now shipping worldwide its laboratory-based total antibody test1 to detect the presence of SARS-CoV-2 IgM and IgG antibodies in blood.
The Radiological Society of North America announced Tuesday, May 26, that amid the global COVID-19 pandemic it has decided to replace its in-person 2020 annual meeting with an all-virtual event.
The novel Coronavirus infection (severe acute respiratory syndrome SARS-CoV-2), which has led to the spread of COVID-19 around the world, has upset normal workflow in hospitals. The increased workload and stress, due to the necessity of implementing safe and separate diagnostic pathways, and the need to constantly monitor the development of the disease after its onset, continues to have a…
As the coronavirus pandemic continues, face masks become a common sight in our everyday lives. However, there is still lots of room for individuality, as these photos prove. Enjoy!
Researchers at Hokkaido University have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a suitable reagent is developed, this technology could be used to detect antibodies against SARS-CoV-2, the causative virus of COVID-19.
Age, male sex, obesity, and underlying illness have emerged as risk factors for severe and fatal cases of COVID-19 in the UK, according to the largest cohort study to date published by The BMJ. As the largest prospective observational study reported worldwide to date, it provides a comprehensive picture of the characteristics of patients hospitalised in the UK with COVID-19 and their outcomes.…
The extremely sensitive olfactory sense of dogs might prove to become a groundbreaking new tool in the fight against the COVID-19. Trained medical scent detection dogs have previously worked with identifying different types of cancers. Researchers at the veterinary and human medicine faculties at the University of Helsinki have now joined forces to identify COVID-19 infected individuals using…
Leading immunologists in Japan are proposing a possible molecular mechanism that causes massive release of proinflammatory cytokines, or a cytokine storm, leading to the acute respiratory distress syndrome (ARDS) in COVID-19 patients. Their suggestions, published in the journal Immunity, are based on recent findings that explain how SARS-CoV-2 enters human cells.
COVID-19 can cause serious cardiovascular complications including heart failure, heart attacks and blood clots that can lead to strokes, emergency medicine doctors at the University of Virgina report in a new scientific paper. They also caution that COVID-19 treatments can interact with medicines used to manage patients’ existing cardiovascular conditions.
A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human cells change upon infection with SARS-CoV-2, the virus causing COVID-19 in people. The scientists tested a series of compounds in laboratory models and found some which slowed down or stopped virus reproduction. These results now enable the search for an active substance…
Researchers from the University of Surrey are applying specialist skills in mass spectrometry to assist in accelerating the search for a Covid-19 vaccine.
Royal Philips has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market a wide range of its ultrasound solutions for the management of COVID-19-related lung and cardiac complications.
Blood stem cells have a surprising ability. In addition to ensuring the continuous renewal of blood cells, they keep track of past infections so that faster and more effective immune responses can be triggered in the future.
More than one in four of the most viewed COVID-19 videos on YouTube in spoken English contains misleading or inaccurate information, reveals the first study of its kind, published online in BMJ Global Health. Public health misinformation on COVID-19 is reaching far more people than in previous pandemics and has considerable potential for harm, warn the researchers. While good quality accurate…
Establishing whether a patient is suffering from severe lung disease, possibly COVID-19, within a few minutes: this is possible using fairly simple ultrasound machines that are enhanced with artificial intelligence. A research team at Eindhoven University of Technology (TU/e) and the University of Trento in Italy has been able to translate the expertise of top lung specialists into a software…
As Covid-19 spreads throughout the country, much attention has been paid to the devastating effects of the virus on the lungs. But doctors are learning how the virus may affect other organs, including the brain. Some patients with Covid-19 have had neurological symptoms, which may include an increased risk of stroke.
A new analysis of the worldwide effort to sequence the coronavirus genome has revealed the scale of the genetic changes that are occurring in the virus known as SARS-CoV-2, as it spreads across the world. These changes have important implications for molecular diagnostics and potentially vaccine success. Led by the London School of Hygiene & Tropical Medicine, the research identified several…
Doctors have reported that partial or total loss of the sense of smell is often an early symptom of infection with SARS-CoV-2, the virus that causes COVID-19. Now, researchers reporting in ACS Chemical Neuroscience have shown that in mice, two proteins required for SARS-CoV-2 entry are produced by cells of the nasal cavity that contribute to odor detection.
Researchers at King’s College London, Massachusetts General Hospital and health science company ZOE have developed an artificial intelligence (AI) diagnostic that can predict whether someone is likely to have COVID-19 based on their symptoms. Their findings are published in Nature Medicine. The AI model uses data from the COVID Symptom Study app to predict COVID-19 infection, by comparing…
Why does every person react differently to an infection with the coronavirus SARS-CoV-2? Why do some people have no symptoms or only mild symptoms of COVID-19, the disease which it causes? And why do some people become so severely ill that they require ventilators or even die? These questions are being investigated by Professor Mascha Binder, director of the Department of Internal Medicine IV at…
Although the clinical symptoms of new pediatric lung disorders such as severe acute respiratory syndrome (SARS), swine-origin influenza A (H1N1), Middle East respiratory syndrome (MERS), e-cigarette or vaping product use-associated lung injury (EVALI), and coronavirus disease (COVID-19) pneumonia may be nonspecific, some characteristic imaging findings "have emerged or are currently…
A British cyber security company, VST Enterprises has signed a contract with international digital health technology firm Circle Pass Enterprises (CPE), owner of ‘Covi-Pass’, to supply 50 million of its ‘digital health passports’ to 15 countries. VST was founded by tech entrepreneur Louis-James Davis to integrate its state-of-the-art VCode & VPlatform technologies into the Covi-Pass…
Despite the use of personal protective equipment (PPE), reports show that many health care workers contracted the coronavirus disease (COVID-19), which raises substantial concerns about the effectiveness of the PPE.
A study of 4532 men in the Veneto region of Italy has found that those who were being treated for prostate cancer with androgen-deprivation therapies (ADT) were less likely to develop the coronavirus COVID-19.
With so many COVID-19 models being developed, how do policymakers know which ones to use?
A course of action to early detect and treat severe courses of COVID-19 infections has been developed by an expert-team of the University Medical Center Goettingen (UMG). A simple urine test is intended to help medical professionals to recognize warning signs of future decompensation of COVID-19 infections earlier. With the help of a few parameters, the treatment of imminent complications can…
It is possible to implement a privacy-respecting contact tracing app that can achieve widespread adoption in the UK, but only if the NHS, rather than the government, run it, researchers at Cass Business School have found. The researchers found that adoption rates increase further if the app is linked to priority testing for COVID-19 for those who get infection alerts. They also found that the…
Researchers at Northwestern University are using artificial intelligence (AI) to speed up the search for COVID-19 treatments and vaccines. The AI-powered tool makes it possible to prioritize resources for the most promising studies — and ignore research that is unlikely to yield benefits. In the midst of the pandemic, scientific research is being conducted at an unprecedented rate. The Food and…
At least half of all patients who survive treatment in an intensive care unit will experience at least one of a triad of problems associated with post-intensive care syndrome, or PICS, and this may be true for people recovering from COVID-19 following ICU care. PICS can manifest as problems with physical function, cognition and mental health, according to a fact sheet from the American Thoracic…
Researchers in virology and veterinary bacteriology at the University of Bern have cloned the novel coronavirus (SARS-CoV-2). The synthetic clones are being used by research groups worldwide to test corona samples, find antiviral drugs and develop vaccines as quickly as possible. The method developed in Bern can also be used in future to combat other highly infectious viruses. In the…
Using machine learning, a team of Western computer scientists and biologists have identified an underlying genomic signature for 29 different COVID-19 DNA sequences. This new data discovery tool will allow researchers to quickly and easily classify a deadly virus like COVID-19 in just minutes – a process and pace of high importance for strategic planning and mobilizing medical needs during a…
Niels-Bjarne Woods, a researcher at Lund University in Sweden, has developed lung-specific mesenchymal stem cells to treat inflammation of the lungs and fibrosis. This research now may be the needed breakthrough for treatment of the severe respiratory issues related to COVID-19. A clinical study may soon be underway contingent on a successful application to the Swedish Medical Products Agency.…
The COVID-19 pandemic could, over the next year, lead to a 20% rise in the number of deaths from people who have been newly diagnosed with cancer, according to research supported by DATA-CAN. The analysis is the first to focus on the impact of the emergency on mortality rates in people with cancer and uses data from the health records of over 3.5 million patients in England.
The COVID-19 pandemic has brought more strain on healthcare systems but it has also highlighted the necessity to integrate social care to healthcare to protect the most vulnerable populations in ageing societies, an eminent healthcare consultant told us in an exclusive interview.
As the coronavirus spreads and infections with Covid-19 further increase throughout Europe, ECMO therapy turns out to be a necessary option for patients with severe courses. Xenios AG provides ECMO consoles that can be used for the treatment of patients who develop severe pneumonia and ARDS with lung failure which also might result from infection with the coronavirus.
Donald Trump has downplayed the risk of COVID-19 and delayed action, costing countless avertable deaths, argue experts in The BMJ. Gavin Yamey, professor of global health and public policy at Duke University, and Gregg Gonsalves, assistant professor of epidemiology at Yale School of Public Health, say Trump’s “astounding incompetence” was a political determinant of the US COVID-19 epidemic.…
Coronavirus can be identified automatically from sick patients’ lung X-rays using artificial intelligence (AI) developed at Brunel University London.
Accident and Emergency departments across the NHS have seen dramatic falls in attendances amid the ongoing coronavirus crisis. Senior A&E practitioners are becoming increasingly concerned that people who need to be seen for serious conditions such as suspected heart attacks are staying away – or not seeking help until much later – because they are frightened of contracting coronavirus.
Hundreds of ICU doctors and nurses are currently fighting for the lives of others. The protective gear they are asked to wear is sealed and heavy, which can cause overheating. Especially for these doctors and nurses, the NOC*NSF has provided hundreds of cooling vests which would have otherwise been used by our athletes at the Olympics. Inuteq, the manufacturers of these cooling vests, is…
As the first country to be hit by COVID-19, China learned a number of early lessons into how to combat the highly-infectious disease. With radiology teams playing an important role and utilising CT chest scans as a diagnostic tool against coronavirus, Chinese practitioners have found themselves well-placed to offer a valuable insight on how to combat and contain COVID-19. In a special webcast –…
COVID-19 has infected millions and killed hundreds of thousands of people worldwide, but a new predictor model devised at the Queensland University of Technology (QUT) offers glimmers of hope, suggesting the worst has passed and indicating well under 1000 deaths for Australia. The team at QUT, led by physician, mathematician and Future Fellow Dan Nicolau, has developed what they believe to be a…
Hospitals and organizations worldwide joined forces with AI imaging company icometrix in a global initiative to leverage artificial intelligence (AI) in the fight against COVID-19. The multinational collaboration resulted in the development of an AI algorithm, icolung, which received CE-marking for clinical use in Europe. icolung is the first CE-marked AI solution for CT resulting from a…
Siemens Healthineers announced it is expanding its infectious disease testing capabilities to aid in the COVID-19 pandemic.
A computational lung model can be used to reduce damage caused by mechanical ventilation – and could increase survival rates for patients significantly.
NEC Corporation announced analysis results from efforts using AI prediction platforms to design blueprints for SARS-CoV-2 vaccines that can drive potent T-cell responses in the majority of the global population. This initiative by the scientific teams within the NEC Group to help combat outbreaks of COVID-19 and support international vaccine development efforts is led by NEC OncoImmunity (NOI) in…
Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells. The identification of these cells by researchers from the Wellcome Sanger Institute, University Medical Centre Groningen,…
To deal with the COVID-19 outbreak, the continuity of the radiology reporting activities is crucial. To guarantee this, care providers are expanding the remote reporting capabilities for their radiology teams. As part of their #StrongerTogether campaign, Agfa HealthCare demonstrates how remote and home reporting solutions can keep imaging workflows going across quarantine lines.
Medical Taiwan, taking place October 15-17 at Taipei Nangang Exhibition Center, Hall 2, features four major themes of medical devices, healthcare products, smart medical solutions and startups in the B2B medical industry. The show will not only showcase Taiwan's medical innovation and technology, but also include this year’s conspicuous theme – epidemic prevention.
The Coronavirus dominates everyday conversation as well as medical and scientific discussions, but in a Leipzig hygiene congress, other topics – such as nosocomial influenza – took a strong position. Dr Andreas Ambrosch, head of the Institute of Laboratory Medicine, Microbiology and Hospital Hygiene at the Brothers of Mercy Hospital in Regensburg, Germany, presented a new study on the spread…
A team of researchers from Empa, ETH Zurich and Zurich University Hospital has succeeded in developing a novel sensor for detecting the new coronavirus. In future it could be used to measure the concentration of the virus in the environment - for example in places where there are many people or in hospital ventilation systems. Jing Wang and his team at Empa and ETH Zurich usually work on…
Scientists at the University of Cambridge have found an association between living in an area of England with high levels of air pollution and the severity of COVID-19, the disease caused by the SARS-CoV-2 virus. Because of the urgent need to share information relating to the pandemic, the researchers have published their report on MedRXiv. It has not yet been peer-reviewed. However, the…
Cancer patients are particularly at risk for infections because of their disease and its treatment. Due to the rapid spread of the coronavirus in Europe, cancer centers within a short period were faced with the challenge of minimizing the risk of infection for these patients while at the same time not compromising the provision of the necessary treatments. Seven leading European cancer centers…
Radiology experts from Norway and Germany highlighted the role of structured reporting in communicating clear results to the rest of the team, to improve patient and staff safety during the pandemic. They also related Germany’s experience of the crisis and what lies ahead in an online conference organized by the European Society of Radiology (ESR) last week.
HM Hospitales, a leading Hospital Group in Madrid, decided to provide the international scientific community with totally anonymized health data regarding patients being treated for the SARS-CoV-2 virus in their facilities.
Drexel University researchers have reported a method to quickly identify and label mutated versions of the virus that causes COVID-19. Their preliminary analysis, using information from a global database of genetic information gleaned from coronavirus testing, suggests that there are at least six to 10 slightly different versions of the virus infecting people in America, some of which are either…
Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published in the Journal of Biological Chemistry.
The UK government should look to veterinary infectious disease know-how to end the current lockdown and abandon its financially ruinous strategy to manage the Covid-19 epidemic, argue two leading vets in a trenchant critique of official policy in this week’s Vet Record.
The pandemic has sparked a cultural change in healthcare and telemedicine use will increase much faster than planned in the near future, according to Vicent Moncho Mas, IT Director at Denia Marina Salud Hospital near Alicante, Spain.
As radiologists worldwide continue to share their knowledge of COVID-19 to help fight the pandemic, two chest experts from France and Spain talked about their country perspectives and the practical experience at their hospital in a dedicated online session organized by the European Society of Radiology (ESR).
European photonics scientists are developing an ultrasensitive laser sensor that detects coronavirus at the earliest point of infection from a saliva or nasal swab in minutes.
The European Stroke Organisation (ESO) cautions against the consequences of the Coronavirus-Crisis on stroke care.
Researchers from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin have released a crucial report in response to the COVID-19 pandemic.
Researchers from Cambridge, UK, and Germany have reconstructed the early “evolutionary paths” of COVID-19 in humans – as infection spread from Wuhan out to Europe and North America – using genetic network techniques.
Hamamatsu and KiKo Knowledge Hub Join Inspirata’s Initiative to Offer Free Remote Pathology Solution for Healthcare Institutions Affected by COVID-19. Inspirata gains strategic support in its initiative to allow pathology departments across the world to offer work-from-home opportunities for their pathologists during the COVID-19 pandemic crisis.
The number of cases tested positive for COVID-19 initially grew exponentially in China, but then slowed down. Dirk Brockmann, professor at Humboldt-Universität zu Berlin (HU) and project group leader at the Robert Koch-Institut (RKI), and his postdoc Benjamin F. Maier have developed a diffusion model that takes into account the effect of social distancing and other measures to explain this…
In order for a COVID-19 vaccine and antiviral drugs to be developed, scientists first need to understand why this virus spreads so easily and quickly, and why it invades our bodies with seemingly little resistance from our immune system. To understand how COVID-19 enters the body and does its damage, a team of top researchers from universities, hospitals and the National Research Council of…
Any new coronavirus vaccine that works well and is safe will still have the daunting challenge of needing to be produced to scale in a very short amount of time. It will also have to be safely delivered into the hands of the most remote populations. The more complex and untested the vaccine approach, the more difficult it will be to both scale its production and deliver it around the world. By…
A new app, which will be used to collect data to develop machine learning algorithms that could automatically detect whether a person is suffering from COVID-19 based on the sound of their voice, their breathing and coughing, has been launched by researchers at the University of Cambridge. The COVID-19 Sounds App is now available as a web app for Chrome and Firefox browsers. Versions for Android…
As the United Kingdom enters its third week of lockdown and the battle against COVID-19 continues, the country’s health and care services are facing an ever-growing number of patients with the condition. The hospital-recorded death toll sat at 5,373 on April 6, up by 439 from 4,934 the previous day, with a total of 51,608 (up 3,802) confirmed cases reported. That compared with 5,683 cases of…
A group of scientists, physicians, funders, and policy makers from over 70 institutions from over 30 countries have launched an international coalition to respond to COVID-19 in resource-poor settings. The COVID-19 Clinical Research Coalition aims to accelerate desperately needed COVID-19 research in those areas where the virus could wreak havoc on already-fragile health systems and cause the…
Siemens Healthineers AG took a big step last October. To incorporate treatment along an entire clinical path, the firm acquired Corindus Vascular Robotics, Inc., to combine image-guided diagnosis with robot-assisted surgery. A couple of months later, the Corindus endovascular robotic system CorPath GRX was used to implant a vascular stent into an obstructed coronary artery – the first use of…
An international team led by University of British Columbia (UBC) researcher Dr. Josef Penninger has found a trial drug that effectively blocks the cellular door SARS-CoV-2 uses to infect its hosts. The findings, published in Cell, hold promise as a treatment capable of stopping early infection of the novel coronavirus that, as of April 2, has affected more than 981,000 people and claimed the…
The number of primary angioplasties – the main treatment for heart attack – has dropped by 40% in Spain since the beginning of the coronavirus lockdown. Other key diagnostic and therapeutic procedures have also considerably diminished. Spanish cardiologists are urging the population to call the emergency medical systems whenever symptoms of myocardial infarction occur, in spite of fears…
An antibody recovered from a survivor of the SARS epidemic in the early 2000s has revealed a potential vulnerability of the new coronavirus at the root of COVID-19, according to a study from scientists at Scripps Research. The study, published in Science, is the first to map a human antibody’s interaction with the new coronavirus at near-atomic-scale resolution. Although the antibody was…
A team of Cardiff University scientists has switched from researching cancer to work that could help towards a vaccine for coronavirus. The team at the School of Medicine usually work on reprogramming viruses so they can target and kill cancer - but are now focusing their efforts to help in the fight against the new virus which is gripping the world. Dr Alan Parker and his team, whose work on…
In a small clinical trial just granted approval, about 30 COVID-19 patients at Karolinska University Hospital may soon begin to receive blood plasma from people who have recovered from the disease. Sweden's Ethical Review Authority has approved the trial treatment, and its effectiveness will be evaluated in a study by researchers at Karolinska Institutet and the Karolinska University Hospital.…
Heraeus Medical, makers of the market-leading PALACOS bone cement, has enhanced its online HeraeusCare orthopedic care coordination solution to a new digital health platform that connects healthcare authorities and providers with patients during the COVID-19 pandemic. “The coronavirus crisis is putting enormous strain on healthcare organizations, with worried patients filling emergency rooms…
Scientists on Standby has been rapidly conceptualised and launched in response to the COVID-19 crisis and in anticipation of the increasing pressure on UK diagnostic testing laboratories and facilities in the coming weeks and months. The portal enables scientists with relevant skills and experience to volunteer their time, expertise and support for COVID-19 screening and testing.
As many nations struggle to keep COVID-19 infection numbers down through increasingly tough public health measures, some point out the island of Taiwan presents an example of how to be prepared in the event of a pandemic. Located less than 150 kilometres from the original viral source – China – Taiwan has seen far fewer cases of the coronavirus in the past month, with a much lower infection…
The severity of the global COVID-19 pandemic has caused lots of countries to face shortage of medical supplies and resources, and some medical care systems are on the brinks of collapsing. Taiwan, with strong medical care capabilities and experiences, is standing with the world as an active member of the global community to provide assistance, exchange experiences and conduct further…
The COVID-19 pandemic is putting extra pressure on radiology services. Radiographers are particularly at risk of catching and spreading the disease. This is why they must follow strict cleaning and disinfection protocols, according to Pablo Valdés Solís, President of the Spanish Society of Radiology (SERAM), who has just published new guidelines on how to protect staff and patients, as the…
Esaote, an Italian company in the field of medical diagnostic imaging systems, recently delivered 103 portable ultrasound scanners in four Italian regions. An operation that confirms the full operation of the Company even during the COVID-19 emergency and strong support to the national health system. Esaote won the tender launched by Consip (central purchasing body procuring goods and services…
China's control measures during the first 50 days of the COVID-19 epidemic may have delayed the spread of the virus to cities outside of Wuhan by several days and, by interrupting transmission nationwide, prevented more than 700,000 infections across the country, according to an international team of researchers.
In response to the global COVID-19 pandemic, Beckman Coulter announced that it is developing assays to identify IgM and IgG antibodies to the coronavirus or SARS-CoV-2. The assays will be designed for use on any of its high-throughput Access family of immunoassay systems, including the Access 2 and DxI series installed globally. Research has shown that after infection with SARS-CoV-2, viral…
Siemens Healthineers announced that its latest critical care testing solution, the RapidPoint 500e Blood Gas Analyzer, has received clearance from the U.S. Food and Drug Administration (FDA), and is now available in the U.S., Europe and countries requiring the CE mark. The analyzer generates blood gas, electrolyte, metabolite, CO-oximetry, and neonatal bilirubin results, which are used to…
Researchers at the German Red Cross Blood Donor Service in Frankfurt headed by Professor Erhard Seifried, and the Institute for Medical Virology at the University Hospital Frankfurt at Goethe University headed by Professor Sandra Ciesek succeeded in developing a procedure that makes it possible to immediately and dramatically increase worldwide testing capacities for detecting SARS-CoV-2.
The world’s only online image-based COVID-19 diagnosis improvement tool for healthcare workers is launched by University of Sydney spinoff DetectED-X, drawing on its global experience and outcomes in breast cancer detection and patient cases from the coronavirus pandemic. The cloud-based technology will help doctors and radiologists diagnose cases faster and more accurately. Computed tomography…
The sense of fear is palpable in the images and videos of hospital intensive care units (ICUs) and emergency departments that are broadcast on television and posted on social media. Fear and heartbreak can be heard in the voices of physicians and nurses who describe what they are experiencing.
In a new study, researchers found that half of the patients they treated for mild COVID-19 infection still had coronavirus for up to eight days after symptoms disappeared. The research letter was published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
A ‘pandemic drone’ to remotely monitor and detect people with infectious respiratory conditions is being developed by the University of South Australia (UniSA) in partnership with a Canadian company. The drone will be fitted with a specialised sensor and computer vision system that can monitor temperature, heart and respiratory rates, as well as detect people sneezing and coughing in crowds,…
Mathematical models can help shed light on the evolution of the coronavirus pandemic, according to Spanish mathematician Juan Luis Fernández Martínez, who predicted Spain could have between 90,000 and 160,000 infected patients. The next trend in epidemic data science will be to issue prediction models that focus on early detection.
A special report by the European Society of Radiology (ESR) addresses the role of radiology in fighting COVID-19. In an expert interview with Prof. Nicola Sverzellati from the University of Parma, Italy, he will share insights on the experience of patient and imaging management in Europe's currently most affected area. Together with ESR Second Vice-President Dr. Adrian Brady from Cork, Ireland,…
Countries where people do not have a habit of washing their hands automatically tend to have a much higher exposure to coronavirus, a new study reveals. University of Birmingham researchers have discovered that at least 50% of people do not have a habit of automatic handwashing after using the toilet in China (77%), Japan (70%), South Korea (61%) and the Netherlands (50%). These countries are…
French in vitro diagnostics company bioMérieux announced that its subsidiary, BioFire Defense, has received Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration of its BioFire COVID-19 test for use in CLIA moderate and high complexity clinical laboratories to detect the novel coronavirus SARS-CoV-2. The test detects SARS-CoV-2 in approximately 45 minutes from a…
The sunny Sunday of March 22, 2020, may well go down as a watershed date in the context of Coronavirus in the UK. A couple of days earlier, UK schools had closed en masse – open only thereafter for children of key workers – and the British government had advised that pubs, bars, cinemas, gyms and restaurants should close and people should adhere more rigorously to social distancing.
The Government and the UK’s Chief Scientific Adviser have backed the UK’s leading clinicians and scientists to map how COVID-19 spreads and behaves by using whole genome sequencing. Through a £20 million investment, the consortium will look for breakthroughs that help the UK respond to this and future pandemics, and save lives. COVID-19 Genomics UK Consortium - comprised of the NHS, Public…
To provide reliable information about the coronavirus disease COVID-19, Professor Giuseppe Lippi, Director of the Laboratory for Clinical Chemistry and Hematology at the University Hospital of Verona, Italy, gives an overview on the current state of scientific knowledge on COVID-19 and the SARS-CoV-2 virus. The video was provided by the American Association for Clinical Chemistry (AACC), who…
The first case of the new coronavirus infection was reported on the 24th January. The strategy taken by the French to stem the spread of the virus and relieve the pressure on the health service may seem draconian to some, but many feel that it is either not strong enough and/or too long in coming because it is only recently that the borders have finally been closed.
As countries worldwide face the challenge of managing the COVID-19 pandemic, Ultimaker is making its global network of 3D printing hubs, experts, and designers directly available to hospitals in need of tools and applications that are short in supply and can be quickly produced with 3D printing.
The hospitals are deploying "ninja robots" to measure fevers and protect the health of overburdened medical workers on the frontlines of the coronavirus outbreak.
The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces, according to a new study from National Institutes of Health, CDC, UCLA and Princeton University scientists in The New England Journal of Medicine. The scientists found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was detectable in aerosols for up to three…
Though the coronavirus disease COVID-19 so far appears to be largely sparing children, researchers are cautioning that it is critical to understand how the virus affects kids to model the pandemic accurately, limit the disease’s spread and ensure the youngest patients get the care they need. The warning comes from Steven L. Zeichner, MD, PhD, the head of UVA Health’s Division of Pediatric…
As coronavirus disease COVID-19 continues to jet and alight invisibly around the globe, scientists now report that the virus has mutated to become two strains: the older ‘S-type’ appears milder and less infectious, while the later-emerging ‘L-type’, is more aggressive, spreads more quickly, and currently accounts for about 70 per cent of cases. Worldwide, medical researchers are exploring…
Chest X-ray is the first imaging method to diagnose COVID-19 coronavirus infection in Spain, but in the light of new evidence this may change soon, according to Milagros Martí de Gracia, Vice President of the Spanish Society of Radiology (SERAM) and head of the emergency radiology unit at La Paz Hospital in Madrid, one of the hot spots for viral re-production of COVID-19.
How long can coronavirus persist on surfaces such as door handles or hospital nightstands? How can the virus be destroyed effectively? A research team from Greifswald and Bochum, Germany, collected the answers scientists can currently offer to these and other pertinent questions and published them in the Journal of Hospital Infection.
The University of Liverpool launched a new website featuring a traffic light system to aid the safe prescribing of experimental drugs being trialled against coronavirus (COVID-19). The site, created by the University’s Liverpool Drug Interactions Group, provides vital information on whether or not combinations of an experimental drug and co-medications are safe to prescribe. This is of…
The World Health Organization (WHO) has officially categorized the current outbreak of the novel coronavirus disease (COVID-19) as a pandemic. Speaking at the COVID-19 media briefing, the WHO Director-General Dr Tedros Adhanom said: "WHO has been assessing this outbreak around the clock and we are deeply concerned both by the alarming levels of spread and severity, and by the alarming levels…
Biotechnology company bioMérieux, a world leader in the field of in vitro diagnostics, is announcing the forthcoming launch of 3 different tests to address the COVID-19 epidemic and to meet the different needs of physicians and health authorities in the fight against this emerging infectious disease. bioMérieux has finalized the development of the SARS-CoV-2 R-Gene test. This real-time PCR test…
As a highly innovative medical specialisation, radiology increasingly takes advantage of the possibilities offered by artificial intelligence (AI). Yet, there is no risk for the future of the specialty. Demands on this discipline are too complex, too communicative. Thus, machines will not replace a radiologist any time soon – of that Uwe Joseph Schöpf, professor of radiology, cardiology and…
The University of Basel is part of the global search for a drug to fight the rampant coronavirus SARS-CoV-2. Researchers in the Computational Pharmacy group have so far virtually tested almost 700 million substances, targeting a specific site on the virus – with the aim of inhibiting its multiplication.
A coronavirus app coupled with machine intelligence will soon enable an individual to get an at-home risk assessment based on how they feel and where they’ve been in about a minute, and direct those deemed at risk to the nearest definitive testing facility, investigators say. It will also help provide local and public health officials with real time information on emerging demographics of those…
Investigators at Hannover Medical School (MHH) in Germany have developed a molecular assay for detecting the novel coronavirus SARS-CoV-2 (previously 2019-nCoV) on the automated Panther Fusion system by Hologic. The preclinical assay is described online in the Journal of Clinical Virology. “Rapid diagnosis is critical to combatting the spread of pandemics, and the Panther Fusion system is well…
The coronavirus last week reached the Netherlands and began to spread around the country. How has the Dutch population reacted? What is a useful frame of reference for this situation? And what are the legal guidelines for dealing with the outbreak? Four researchers from the University of Amsterdam – a clinical microbiologist, an anthropologist, a social scientist and a health lawyer – explain…
The 2020 edition of the European Congress of Radiology (ECR) in Vienna, which had been postponed due to safety concerns regarding COVID-19, will not take place on site this year. Instead, the congress organisers at the European Society of Radiology (ESR) opt for an online-only event: "It is with a heavy heart and much regret that the Board of Directors of the European Society of Radiology…
In a joint effort, the U.S. Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) take action to make more respirators, including certain N95s, available to health care personnel. Currently, the majority of respirators on the market are indicated for use in industrial settings. This action allows certain National Institute for Occupational Safety and Health…
In a study of more than 1,000 patients published in Radiology, chest CT outperformed lab testing in the diagnosis of 2019 novel coronavirus disease (COVID-19). Researchers at Tongji Hospital in Wuhan, China, concluded that CT should be used as the primary screening tool for COVID-19. In the absence of specific therapeutic drugs or vaccines for COVID-19, it is essential to detect the disease at an…
A University of British Columbia (UBC) researcher is part of an international team working with a biotechnology company on a pilot clinical trial of a potential new treatment for patients with severe coronavirus infections in China. Dr. Josef Penninger, director of UBC’s Life Sciences Institute and Canada 150 Chair in Functional Genetics, is working closely with Vienna-based Apeiron Biologics…
The current outbreak of the novel coronavirus disease (COVID-19) is making headlines by the minute. However, some less-than-trustworthy advice can be found among the information. Understandably, many people are concerned and confused. To prevent unnecessary panic, the World Health Organisation (WHO) has assembled advice for the public. Is it safe to receive parcels from China? Will sesame oil…
WHO Chief Adhanom Ghebreyesus has declared the novel coronavirus (SARS-CoV-2) a global health emergency. He said the decision was reached not because of the situation in China, but because of, “what is happening in other countries.” On Feb. 17, the number of infections totaled around 71,000 globally based on data of the WHO. COVID-19 – the official shorthand name of the novel corona virus…
Infrared thermometers are now used in most subway stations in China to prevent the spread of novel coronavirus (SARS-CoV-2) pneumonia (MCP). Many stations have implemented an artificial intelligence (AI) based fever screening system developed by the Beijing-based company Megvii Technology Limited. The system supports non-contact remote temperature screening from a distance of 3 meters. "This…
Research into the novel Wuhan seafood market pneumonia virus, the deadly "coronavirus" that has forced the Chinese government to quarantine more than 50 million people in the country's dense industrial heartland, will be facilitated by the UC Santa Cruz Genomics Institute. The Genomics Institute's Genome Browser team has posted the complete biomolecular code of the virus for researchers…
Scientists at the University of Bologna have conducted the largest analysis of coronavirus 2019-nCoV genomes sequenced so far. This analysis confirms that the virus originates in bats and shows a low variability: the virus heterogeneity is low. At the same time, researchers identified a hyper-variable genomic hotspot in the proteins of the virus responsible for the existence of two virus…
The situation is extraordinary: there have only ever been four declarations of public health emergencies of international concern in the past and now there are two at the same time. Whilst the risks associated with the novel coronavirus are still unclear, people in the Democratic Republic of the Congo are still battling with an outbreak of the deadly Ebola virus which has been ongoing since 2018…
The novel coronavirus that recently originated in Wuhan, China has grabbed headlines and caused concern among public health officials around the world. Two infectious disease experts share their insights on the novel coronavirus epidemic.
Scientists from The Peter Doherty Institute for Infection and Immunity in Melbourne have successfully grown the Wuhan coronavirus (also known as SARS-CoV-2) from a patient sample, which will provide expert international laboratories with crucial information to help combat the virus. This is the first time the virus has been grown in cell culture outside of China. The Royal Melbourne Hospital’s…
Nine people have died and more than 400 have been sickened by the new corona virus spreading in China. A few cases have been confirmed in Taiwan, Thailand, South Korea, Japan and the U.S., and on Wednesday, the World Health Organization is holding an emergency meeting on the outbreak. How worried about a new pandemic should we be? Virus researcher Ali Mirazimi, adjunct professor at the Department…
The use of Artificial Intelligence (AI) in clinical settings is already a reality, one that has brought benefits to patients, healthcare stakeholders and wider society. These developments have now been highlighted in a library of use cases on ‘Artificial Intelligence in Healthcare’, published by COCIR. The publication of this library of use cases fulfils COCIR’s commitment in its April 2019…
Robocath, a company that designs, develops and commercializes cardiovascular robotic systems for the treatment of vascular diseases, announces it has successfully completed its first robotic coronary angioplasties with R-One in Germany. The Percutaneous Coronary Interventions (PCI) were performed by Pr Michael Haude, a recognized and highly experienced interventional cardiologist at Rheinland…
A technique that enables patients suffering from heart conditions to hold their breath safely for over 5 minutes could have potential as part of a new treatment for cardiac arrhythmias, say researchers at the University of Birmingham. In a new study, published in Frontiers in Physiology, researchers initially proposed the technique as a new means for earlier diagnosis of ischaemic heart disease.…
An exciting development from an innovative French company is poised for a major breakthrough in European markets. As is now well-known, coronary angioplasty is a procedure that widens and/or unblocks the arteries to the heart by the insertion and inflation of a balloon and/or stent into the vessel lumen. In modern practice, a stent is normally left in place to ensure the blood flow remains…
A new prospective study based on data from the Women's Health Initiative found a potential inverse association between dietary magnesium and fatal coronary heart disease in postmenopausal women. The study, which also showed a trend between magnesium and sudden cardiac death in this population, is published in Journal of Women's Health. Charles Eaton, MD, Alpert Medical School of Brown University,…
Robocath, a company that designs, develops and commercializes cardiovascular robotic systems for the treatment of vascular diseases, announced it has successfully completed six robotic coronary angioplasties with R-One, a first for the continent of Africa. The Percutaneous Coronary Interventions (PCI) were performed by Dr Faizel Lorgat, an interventional cardiologist at the Netcare Christiaan…
Obesity not only means someone is overweight but, over time, they will probably suffer sequelae that increasingly impair quality of life and are potentially fatal – these include hypertension, coronary heart disease, type two diabetes, pulmonary function disorders, tumours, plus an increased risk during surgery and anaesthesia. In patients with morbid obesity, class three obesity, according to…
Consider the diagnostic and therapeutic possibilities resulting from access to pertinent data from thousands of anonymized patient medical scans. What new patterns, options, or evidence for actionable insights could be derived from all this information? Cloud-based data is easily accessible via computer, smartphone, or tablet and is a valuable complement to the insights from the millions of…
With KardioKompassi, researchers from the University of Helsinki have developed an interactive web tool that aims to predict and prevent cardiovascular disease. The application for patients and doctors uses traditional health information combined with genome information, including 49,000 DNA variations associated with the disease. Using this data, the risk calculator evaluates the risk of cardiac…
Researchers in Zurich have recently been able to monitor the corrosion of bioresorbable magnesium alloys at the nanoscale over a time scale of a few seconds to many hours. This is an important step towards accurately predicting how fast implants are resorbed by the body to enable the development of tailored materials for temporary implant applications. Magnesium and its alloys are increasingly…
Tiny particles that can fight cancer or that can easily pass through any interface within our body are a great promise for medicine. But there is little knowledge thus far about what exactly will happen to nanoparticles within our tissues and whether or not they can cause disease by themselves. Within an international research consortium, Empa scientists have now developed guidelines that should…
Robocath announces the success of its first two coronary angioplasties performed with assistance from its R-One robotic platform.
Humans are inherently risk-averse: We spend our days calculating routes and routines, taking precautionary measures to avoid disease, danger, and despair. Still, our measures for controlling the inner workings of our biology can be a little more unruly. With that in mind, a team from MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) came up with a new system for better…
Martin Möckel and Dorothee Riedlinger, from the Charité Medical University Berlin, Emergency and Acute Medicine Campus Virchow-Klinikum, and Campus Charité-Mitte report on POCT testing in the A&E Department to screen for Staphylococcus aureus colonisation of the nose or throat. People colonised with Staphylococci are at increased risk of developing a nosocomial, i.e. hospital acquired…
Technology developed using artificial intelligence (AI) could identify people at high risk of a fatal heart attack at least five years before it strikes, according to new research funded by the British Heart Foundation (BHF). The findings are being presented at the European Society of Cardiology (ESC) Congress in Paris and published in the European Heart Journal. Researchers at the University of…
New research at the University of Kentucky has confirmed that the presence of XX sex chromosomes increases the amount of fat circulating in the blood, which leads to narrowing of the arteries and ultimately a higher risk of heart attacks and coronary artery disease. The research was published in Nature Communications. The leading cause of death in women is coronary artery disease (CAD), but women…
ESC Congress, Paris: Two key strands in the ‘Controversies in imaging coronary artery disease’ session at the congress will examine the pros and cons of imaging use for coronary artery disease risk stratification in asymptomatic patients; the second strand will focus on whether CT angiography should be the first choice for imaging coronary artery disease in patients with stable chest pain.…
Cardiovascular magnetic resonance (CMR) imaging has become faster, simpler and more widely available in recent years because it has evolved to deliver effective assessment and diagnosis of a range of heart conditions with expanding guideline indications.
Uwe Joseph Schoepf, Professor for Radiology, Cardiology and Paediatrics and Director of the Department of Cardiovascular Imaging at the Medical University of South Carolina, discusses areas of application for AI-based radiology. The cardiothoracic imaging expert and his team were largely involved in the development and early clinical trials of the Siemens AI-Rad Companion Chest CT, a software…
Findings from a comparative outcome study have highlighted the benefits of using cardiovascular magnetic resonance imaging (CMR) perfusion imaging as a first-line ischaemia test in patients with moderate risk of coronary artery disease (CAD). The MR-INFORM (Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease) trial, which began in 2012 (results published in the New England…
A remarkable number of studies and innovations were presented at the 30th anniversary of Transcatheter Cardiovascular Therapeutics (TCT) meeting in San Diego, California. TCT 2019 will take place in San Francisco, CA between 25-29-Sep-2019. On the clinical side, the long-expected results from COAPT trial studying MitraClip device in patients with secondary mitral regurgitation and heart failure…
Interventional cardiologists have been aware of the value of intracoronary (IC) imaging in clinical practice for more than twenty years. However, recent developments and improvements in modalities and software have enabled huge strides in its range and scope for both diagnostic assessment and in percutaneous coronary interventions. Imaging options now include intravascular ultrasound (IVUS),…
On the centenary of his birth, Mark Nicholls reflects on the life and legacy of Nobel laureate Sir Godfrey Newbold Hounsfield, the man who pioneered computed tomography. It was a discovery that came from a moment of inspiration during a country walking holiday; the idea that one could determine what was inside a box by taking X-ray readings at all angles around the object. From that, Sir Godfrey…
The latest study by the German Society for Haematology and Oncology (DGHO), ‘Prognosis for population-based morbidity for common cancers in Germany – impact on provision’ has made it clear that due to demographic developments in Germany and to medical advances in oncology, the requirements for cancer patients’ care are ever more diverse. The increase in newly diagnosed cancer patients is…
Researchers at ETH Zurich have developed a new method for producing malleable microstructures – for instance, vascular stents that are 40 times smaller than previously possible. In the future, such stents could be used to help to widen life-threatening constrictions of the urinary tract in foetuses in the womb. Approximately one in every thousand children develops a urethral stricture,…
With a case fatality rate of 35 percent, a Middle East respiratory syndrome-related coronavirus (MERS-CoV) infection – also called camel flu – is a dangerous disease. About seven years ago, when the virus was first isolated, mortality was close to 100 percent since only severe infections that led to the patient being in intensive care were recorded. Today the environment of each victim is…
Researchers from King's College London have found that therapy that can induce heart cells to regenerate after a heart attack.
A discovery by researchers at Queen’s University Belfast and King’s College London (KCL) could revolutionise treatment for vascular and diabetes related cardiovascular diseases.
When Olivia Nelson was 3 years old, her parents noticed that she had a fever that wouldn’t get better. They brought her to a nearby hospital, where she spent about two weeks being screened for diseases. As doctors tried to find a diagnosis, a lymph node on Olivia’s neck became swollen. Alarmed and wanting an answer, the Nelsons asked to transfer to Seattle Children’s. “It was very…
Longer hours, more demanding working practices, complex cases and increased administration are taking their toll on physicians as growing numbers, across a range of specialties, report signs of burnout. All this despite technological advances such as artificial intelligence and machine learning to aid diagnosis, read and interpret images, improve workflow and enhance decision-making.
Forty-two percent of all deaths in the United States are related to cardiovascular disease (CVD). According to the Global Cardiovascular Drugs Market Forecast, by 2030 the number of deaths from CVD will rise to 23.6 million per year in the U.S. alone. Along with increased deaths, spending on drugs to treat CVD as well as related hospital stays, home health care and lost productivity will also…
Patients who undergo heart surgery do not experience major memory changes—either better or worse—when compared with those who have a much less invasive, catheter-based procedure, according to a study published online in The Annals of Thoracic Surgery. “It was comforting to see that the differences in cognitive decline between the two heart procedures are small, even though one involves…
Built as the first commercially available scanner to deliver truly digital PET, the Vereos PET/CT, from Philips, offers revolutionary Digital Photon Counting technology. The science behind this scanner evolution is ‘quite complicated’, agrees Piotr Maniawski, Director of Clinical Science Nuclear Medicine at Philips Healthcare, yet the improved performance is significant, particularly when…
Professor Marc Dewey, Vice Chair of the Department of Radiology at Charité - Universitätsmedizin Berlin, made value-based radiology the main theme of the Wilhelm Conrad Röntgen Honorary Lecture during ECR 2018. Radiology practice needs change, he said, and radiologists should grasp at new technology to drive their future. His lecture was summarised in a recent comment in The Lancet.
Cardiologists in the UK are trialling an artificial intelligence (AI) system that will help better diagnose heart disease. Devised by researchers from the University of Oxford, it can predict heart disease and cardiac events from ultrasound stress test images with initial results showing that the AI system is far more accurate than conventional techniques. Paul Leeson, Professor of Cardiovascular…
Nanomedicine is set to play an increasingly important role in the future diagnosis and treatment of cardiovascular disease. Understanding the importance of nanomedicine was enhanced by four experts who spoke at the British Cardiovascular Society conference held in June. The technology – dealing with dimensions and tolerances of less than 100 nanometres and especially the manipulation of…
Researchers at Cleveland Clinic, University of Oxford, and University of Erlangen have identified a novel imaging biomarker – and found it can be used to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries.
A major study has been launched to investigate the interaction between genes and lifestyle factors and dilated cardiomyopathy (DCM). Led by Professor Stuart Cook, at the National Heart and Lung Institute, this, the largest ever DCM study, will investigate why people develop DCM, with a focus on who is most at risk of sudden death or heart failure (HF). Six hospital trusts across England –…
Experts outlined approaches to ischaemia imaging during the recent British Cardiovascular Society conference. In a ‘Detection of ischaemia by cardiac imaging in 2018’ session, comparisons were made between solid state SPECT cameras, whether spatial resolution or visual assessment was of the greater importance, if CT-FFR offered advantages over CT perfusion, and the challenges in defining a…
MRI has a central role in picking up myocardial infarction with non-obstructive coronary disease, a condition that particularly affects women but is often left untreated, with potentially fatal outcome. Heart attack in women presents differently than in men and requires a different approach when it comes to detection and prevention, according to cardiologist Allison Hays.
Nanomedicine will play an increasingly important role in future diagnosis and treatment of cardiovascular disease, a subject explored in detail by four expert speakers at the British Cardiovascular Society conference in Manchester in June. The conference heard that the technology – dealing with dimensions and tolerances of less than 100 nanometres, especially the manipulation of individual…
While the question is still debated as to whether MRI is the better CT, along comes a potential game changer – a new data based 3-D reconstruction method of heart anatomy and function that aims to replace diagnostic coronary angiography. In the near future not only adult patients with coronary heart disease could benefit from this new technique but also children with complex congenital heart…
For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory…
People who abstain from alcohol or consume more than 14 units a week during middle age (midlife) are at increased risk of developing dementia, finds a study in The BMJ today. However, the underlying mechanisms are likely to be different in the two groups. As people live longer, the number living with dementia is expected to triple by 2050. So understanding the impact of alcohol consumption on…
The clinical performance of Beckman Coulter's high-sensitivity troponin I (hsTnI) assay Access hsTnI has been validated in a study. Within 2 hours, the assay delivers an accurate assessment of patients with suspected acute coronary syndrome (ACS).
A new software to calculate the pressure drop and vFFR value (vessel Fractional Flow Reserve) in the coronary artery non-invasively was presented to interventional cardiovascular experts at EuroPCR 2018 in Paris. The software called CAAS vFFR (Cardiovascular Angiographic Analysis Systems for vessel Fractional Flow Reserve) was developed by Pie Medical Imaging (Esaote Group). The vFFR calculation…
Triggers of acute heart failure vary globally, according to late breaking results from the REPORT-HF registry presented at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. REPORT-HF is a global, prospective registry comparing regional differences in causes of acute heart failure, therapies, time to treatment, and outcomes. Professor Sean…
People who consume an egg a day could significantly reduce their risk of cardiovascular diseases compared with eating no eggs, suggests a study carried out in China, published in the journal Heart. Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, including China, mostly due to ischaemic heart disease and stroke (including both haemorrhagic and ischaemic…
A recently identified pig virus can readily find its way into laboratory-cultured cells of people and other species, a discovery that raises concerns about the potential for outbreaks that threaten human and animal health. Researchers at The Ohio State University and Utrecht University in the Netherlands collaborated to better understand the new virus and its potential reach. Their study, the…
AI-based applications will replace radiologists in some areas, the physicist Bram van Ginneken predicts. ‘The profession of radiologist will change profoundly,’ predicts Gram van Ginneken, Professor of Medical Image Analysis at Radboud University Medical Centre. The cause is automatic image analysis by computers (first published in a paper in 1963) and deep learning.
An international research group, including scientists at the University of Maryland School of Medicine, studying 520,000 people from around the world has identified 22 new genetic risk factors for stroke, tripling the number of gene regions known to affect stroke risk. The results show that stroke shares genetic influences with other vascular conditions, especially blood pressure, but also…
The recent ACC/AHA Guidelines have increased the number of patients said to have hypertension by up to 40 percent (new 130/80 mmHg). The international recommendation is to treat hypertension with angiotensin converting enzyme inhibitors (ACEIs). These drugs, however, have significant adverse effects: Often a chronic dry cough leads to patients withdrawing from treatment. On rare occasions, ACEIs…
High drug prices as well as the excessive use of imaging and surgical procedures, and excessive administrative burdens contribute the majority to America’s health care overspending compared to Europe, argues policy expert Ezekiel J. Emanuel, MD, PhD, chair of the department of Medical Ethics and Health Policy at the Perelman School of Medicine at the University of Pennsylvania, in an editorial…
The Clinica Creu Blanca Diagnostic Group in Barcelona, Spain, is the first clinic in Europe to use Canon Medical System’s new Celesteion PET-CT Scanner. Dr. Xavier Alomar, Head of the Diagnostic Imaging Department at the Clinic, explains how the new system has opened up a large field of diagnostic possibilities for the Group in Metabolic Medicine in Oncology, Neurology, Cardiology and…
The New Horizons Lecture at the RSNA annual meeting is a keynote address that looks to the future, and the inventor of a major innovation in magnetic resonance imaging (MRI) technology, Daniel K Sodickson MD PhD, did just that. His lecture entitled ‘A New Light: The Birth and Rebirth of Imaging’ looked back at how MRI has evolved and forward at what it will become.
In the next five to 10 years, artificial intelligence is likely to fundamentally transform diagnostic imaging. This will by no means replace radiologists, but rather help to meet the rising demand for imaging examinations, prevent diagnostic errors, and enable sustained productivity increases.
Texas Biomedical Research Institute and The Children’s Hospital of San Antonio have joined forces to cure a mysterious condition called Kawasaki disease. The illness which affects young children is named after the Japanese doctor who first described it more than 50 years ago. However, researchers still do not know what causes the rashes, fever, and artery damage. Some type of infectious agent…
Smoking just one cigarette a day carries a much higher risk of developing coronary heart disease and stroke than expected – about half the risk of smoking 20 per day –concludes a University College London (UCL)-led review of the evidence. The researchers say their findings, published in the BMJ, have important consequences for many smokers and health professionals who believe that smoking…
Nearly a quarter of patients with chronic ischaemic cardiovascular disease are dead or hospitalised within six months, reports a European Society of Cardiology (ESC) study published in the European Journal of Preventive Cardiology. “Coronary artery disease is the leading cause of death worldwide yet some patients appear to get lost in the system after their initial visit to a hospital or…
Coordinating the response to heart attacks among emergency responders and hospitals reduces the time to treatment and saves lives - even on a large, regional scale, according to a study led by the Duke Clinical Research Institute with support from the American Heart Association. In the largest demonstration of the coordinated approach - 132 hospitals and 946 EMS agencies in 12 U.S. regions -…
Carestream shows imaging analytics software that can improve early detection rates for many conditions as part of its Clinical Collaboration Platform (CCP). This software can calculate liver density from a CT chest or abdomen study to detect a fatty liver; identify emphysema by detecting levels of trapped air in the lungs from a non-contrast CT chest study; and determine levels of coronary…
If you have a heart attack or stroke, it’s important to get your “bad” cholesterol measured by your doctor on a follow up visit. Researchers have found that one step is significantly associated with a reduced risk of suffering another serious cardiovascular episode. The new research, conducted by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City, found that…
Providing insights into new cardiac testing methods, Professor Stefan Holdenrieder, Director of the Institute of Laboratory Medicine at Munich’s German Heart Centre, explained why biomarkers are a game changer in diagnostics.
A new blood test to detect heart attacks has been developed by a team of researchers at King’s College, London, which could speed up diagnosis, according to results from pan-European trials. The test is quicker than the standard test, which combines an ECG with a blood test to measure the levels of troponin. Under current guidelines, suspected heart attack cases are tested for high blood…
Despite prevention efforts, researchers have found a significant increase over a 10-year period in the percentage of people with stroke who have high blood pressure, diabetes, smoking and other risk factors for stroke. “An estimated 80 percent of all first strokes are due to risk factors that can be changed, such as high blood pressure, and many efforts have been made to prevent, screen for and…
Carestream Health is demonstrating advanced imaging analytics software tools designed to enhance value in the delivery of medical care as part of its Clinical Collaboration Platform at the SIIM Machine Learning Showcase being held Sept 26-27 at Johns Hopkins Hospital in Baltimore, Md.
Point-of-care ultrasound plays an important role in the emergency sector, enabling hospital clinicians and paramedics responding to an urgent call for medical assistance to assess a patient’s condition. Dr Matthew Reed, an Emergency Medicine consultant at the Royal Infirmary of Edinburgh, explained how ultrasound contributes to the management of cardiac arrest.
The first health economics data from the Global Anticoagulant Registry in the Field – Atrial Fibrillation (GARFIELD-AF) was presented at ESC Congress 2017, organised by the European Society of Cardiology, in Barcelona, Spain.
Scientists in the United Kingdom are investigating the potential of a new regenerative and tissue engineering technique that could transform veins into arteries to improve the outcomes for patients undergoing heart bypass surgery.
Shielding cardiologists from harmful radiation is the goal for two systems capable of navigating the vascular highway.
A formerly bitter competition between cardiology and cardiac surgery is increasingly replaced by constructive cooperation. The Austrian Society of Cardiology (ÖKG) even held its annual congress along with the Austrian Society of Thoracic and Cardiovascular Surgery this year.
Celebrating 40 years of PCI, cardiologists fret over their future with big data, machine learning and robots.
With 4,500 accepted abstracts, 600 sessions and 30,000 expected attendees, ESC Congress 2017 is undoubtedly the world’s largest cardiovascular event. On healthcare-in-europe.com, Dr Stephan Achenbach, Congress Program Committee Chairperson, gives an overview of issues and events unfolding in Barcelona from August 26-30.
Coronary angioplasty is arguably the most revolutionary breakthrough in the history of cardiology. While the technique is today performed on millions of patients worldwide, its origins can be traced back to Zurich, Switzerland, in the late 1970s.
Breast implants may impede an electrocardiogram (ECG) and could result in a false heart attack diagnosis, according to research by the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC).
Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure. The study, “Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction” suggests that inhibiting this protein could help treat a disease that affects more than 20 million people worldwide.
Researchers have found that people with A, B, and AB blood types may be at greater risk of cardiovascular events - particularly heart attack - than individuals with O blood types.
The ‘Transmission, Prevention, and Reporting of Emerging Infectious Diseases’ program for the International Conference IMED 2016 in Vienna, this November, reflected events in the field of emerging diseases that have occurred over the last two years. Therefore, key congress topics included the Zika virus, the effects of global warming and the unusually high number of hospital-acquired…
Researchers are revisiting their views on the relative dangers soft and hard atherosclerotic plaque deposits pose to heart health. Findings of a new study by researchers at the Intermountain Medical Center Heart Institute may be a “game-changer” for determining who’s at risk of a heart attack, they say.
Royal Philips today announced that the results from two large clinical trials comparing patient outcomes using instant wave-free ratio (iFR) and fractional flow reserve (FFR) in the diagnosis and treatment of heart disease have been published in the New England Journal of Medicine. First released in 2013, iFR is an innovative pressure-derived index unique to Philips, a global leader in…
The ‘Transmission, Prevention, and Reporting of Emerging Infectious Diseases’ programme for the International Conference IMED 2016 in Vienna, this November, reflected events in the field of emerging diseases that have occurred over the last two years.
Like spicy food? If so, you might live longer, say researchers at the Larner College of Medicine at the University of Vermont, who found that consumption of hot red chili peppers is associated with a 13 percent reduction in total mortality – primarily in deaths due to heart disease or stroke – in a large prospective study. The study was published recently in PLoS ONE.
Over 3.5 million cardiac catheterisations are performed in Europe each year. A study jointly conducted by radiologists and cardiologists at Charité – Universitätsmedizin Berlin and published in the latest issue of The BMJ compares CT with cardiac catheterisation in patients with atypical chest pain and suspected coronary artery disease (CAD). Please find below a few details regarding the…
Waiting for test results can be a minor inconvenience for some patients, but for those who are critically ill, timing matters. At the CPOCT International Symposium in Copenhagen (21-24 September) Dr Craig Lilly, a professor of medicine at the University of Massachusetts spoke about the point-of-care testing market, outlining currently available testing for critically ill adults, and also under…
From the beginning of MRI scientists dreamed of not only translating data sets into images, but also classifying tissue directly. Five years ago this would still have been inconceivable.
Greater sensitivity and versatility of devices, as well as more patient-friendly implantation options, were issues outlined at the CardioStim 2016 EHRA Europace world congress on cardiac electrophysiology, held in Nice, France.
To sharply focus on the specialised requirements in echocardiography, Toshiba engineers built from scratch the Aplio i900CV with a total redesign of hardware and software. The new Aplio i-series is a premium addition to the award-winning Aplio 500 platform, which today is used in more than 31,000 clinical settings worldwide.
Stroke patients will first undergo a CT scan as they enter the hospital. Before any further imaging scan is carried out, the medical team must decide whether they need to intervene intra or extra cranially. ‘Imaging enables you to see which pathology you are dealing with and helps you select patients for either recanalisation or revascularisation or, in some cases, occlusion by embolisation,’…
Coronary interventions often rely more on art than science as the decision to treat a patient tends to be based on what clinicians can see, a subjective interpretation of cardiac imaging. Two new techniques have emerged for cardiovascular diagnostics that are enabling software to help surgeons and cardiologists measure, and thereby better manage cardiac disease.
Coronary or peripheral bypasses are the most frequently performed vascular operations. Although one million patients per year and around the world, undergo this intervention, its failure rate reaches 50%, because of poor vessel healing, leading to vessel graft occlusion. To improve the outcome of bypasses, researchers from the University of Geneva (UNIGE) work together with medical doctors from…
Topics of big data, the genetic basis of coronary artery disease and sudden cardiac death in the young are among key subjects for British cardiologists at their 2016 annual conference. With a central theme of “Prediction and Prevention”, the 2016 British Cardiovascular Society annual conference takes place in Manchester from June 6-8 and features innovative and interactive presentations,…
The University Hospital Jena (UKJ) is the first one in Germany and one of the first in Europe to use the GE Revolution CT for faster diagnostics in an emergency center. Thanks to innovative technology, several steps of the examination can now be done in one single scan, exposing the patient to a quite low radiation dose.
Since launching Somatom Definition in 2005, Siemens has continued to develop Dual Source technology in order to overcome the remaining challenges in computed tomography. This significant development has made it possible to produce diagnostic images of a patient’s beating heart and coronary vessels without having to artificially lower their heart rate, for example. Scanning speeds that were…
For the examination of coronary blood vessels, intravascular methods with imaging technologies are already state-of-the-art. However, ultrasonic methods, which are used to gather information about the tissue, can only be used externally, up to now. The piezo electronical components necessary for this have not been sufficiently miniaturized to be inserted into the blood vessels.
Despite messages to the contrary, most women being seen by a doctor for the first time with suspected heart disease actually experience the same classic symptoms as men, notably chest pain and shortness of breath, according to a study led by the Duke Clinical Research Institute.
Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs. The study was published in the Journal Nanomedicine: Nanotechnology, Biology, and Medicine.
With precision imaging playing a greater role in daily radiology practice as patients receive ever more personalised care, the detail and extent of that shift is outlined in the ECR session ‘Personalised radiology: myth or reality?’, which includes a presentation from renowned radiologist Professor Gabriel Krestin, chairman of the radiology and nuclear medicine department at Erasmus MC,…
CT angiography (CTA) is evolving from a morphological – anatomical – to a functional imaging modality. In the past two years, cardiac CT perfusion measurement techniques were launched that predict which lesion will cause a reduction in blood flow.
Humabs BioMed SA and the Institute for Research in Biomedicine (IRB) affiliated to the Università della Svizzera italiana announced the identification, isolation and characterization of two Ebola virus neutralizing monoclonal antibodies from the blood of a survivor of an Ebola infection.
One thing is certain in big data discussions: Intelligent machines will change our world considerably. What is less certain is exactly how these changes will look. Although networked data processing offers many opportunities, its development is still in the early stages.
The CSI Congress (Congenital, Structural and Valvular Interventions) is one of the major fixtures for catheter therapy of congenital and structural heart defects. Key moments in this high profile event are live broadcasts and the audience can not only to listen to but also interact with the teams in the cath labs involved.
Since 2012, at least 1,500 individuals have developed Middle East respiratory syndrome (MERS), resulting in more than 500 fatalities. Only now are results being reported of the first autopsy of a MERS patient, which was performed in 2014. Not only do these findings, published in The American Journal of Pathology, provide unprecedented, clinically-relevant insights about how MERS progresses, they…
Automated latex enhanced immunoturbidimetric H-FABP assay helps emergency departments to detect MI within 30 minutes of chest pain onset, and improve the diagnostic efficiency of Troponin.
Leading cardiologist Valentin Fuster, MD, PhD, has developed a free mobile application called “Circle of Health” to empower individuals around the globe to take action to comprehensively assess and enhance their daily overall heart health. Cardiovascular diseases are the number one cause of mortality in the world. Dr. Fuster has created “Circle of Health” for the daily promotion of…
In the year of its 140th anniversary, Shimadzu has released the new Trinias MiX package (Minimally invasive eXperience) to support less invasive treatments through a variety of applications. The Trinias MiX package is an exten¬sion of the Trinias angiography system, which facilitates high-level interventions through proprietary image processing technology. Shimadzu provides functional…
Eating more fruits and vegetables as a young adult may keep your arteries free of heart disease 20 years later, according to research in the American Heart Association journal Circulation.
Cardiac catheterisation is the gold standard for diagnosing coronary artery disease (CAD), the main cause of death worldwide. More than 3.5 million invasive coronary angiographies (ICAs) are performed in the European Union each year, tendency rising. Nearly 60 percent of these minimal invasive examinations do not result in further treatment, since the patients do not have obstructive epicardial…
Ultrasound is finding relatively new applications across various clinical specialties and points of care, from image-guiding interventions, biopsies and non-invasive diagnosis to imaging in war and sports fields. Cost effectiveness, safety, high accessibility and clinical value in preliminary diagnosis are strengthening the technology’s value proposition. It is seen as the definitive diagnostic…
Coronary artery disease (CAD) is the major killer worldwide. Its early detection can save the lives of many. Computed tomography (CT) has shown tremendous results in this area, but its advantage over more invasive techniques remains to be demonstrated, especially in patients with low to moderate risk.
Researchers have identified a new test that can be used to predict the likelihood of a patient developing heart failure, or even dying following a heart attack.
A ground-breaking genetic testing programme for an inherited and potentially-deadly high cholesterol condition has been extended to more United Kingdom health trusts.
World-renowned cardiologists reviewed the latest trends and dose reduction strategies in cardiac CT during the International Conference on Nuclear Cardiology and Cardiac CT (ICNC) that unfolded in Madrid in May.
PET/MR has long been studied for oncology but the technique also holds promise in cardiovascular applications, according to a panel of experts at the recent International Conference on Nuclear Cardiology and Cardiac CT (ICNCT).
Imaging modality complements a stress test in diagnosing the aetiology of chest pain, according to an expert speaking at the International Conference on Nuclear Cardiology and Cardiac CT (ICNC) held this May in Madrid.
Philips Minicare delivers rule-in/rule-out readings for heart attacks in 10 minutes. It takes a lot of hard work to make things easy. Biomedical experts at Royal Philips have spent more than 10 years developing a simple test for the emergency department that, in less than 10 minutes, may indicate whether a patient suffering chest pains is having a heart attack.
Come and visit us at booth A300 at the ESC in London. SCHILLER is delighted to present you its latest innovations!
The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, and the American Society of ExtraCorporeal Technology have released a set of clinical practice guidelines to address management of a patient's temperature during open heart surgery. The guidelines appear in the August issue of The Annals of Thoracic Surgery and were published simultaneously in two other journals.
As the South Korean epidemic of Middle East Respiratory Syndrome (MERS) continues unabated, researchers have raced to find treatments for the deadly virus, which has killed more than 400 people since it was first discovered three years ago in Saudi Arabia.
Following the BMA’s call for a 20% sugar tax to subsidise the cost of fruit and vegetables, experts in The BMJ this week debate whether a sugar tax could help combat obesity.
A growing number of clinical tests are being delivered in community hospitals with more patients receiving quicker, accurate diagnoses closer to home, without stays in acute hospital beds. Professor Daniel Lasserson, an Associate Professor in the Nuffield Department of Primary Care Health Sciences at Oxford University, shares the opinion that using point-of-caretesting (POCT) to facilitate high…
Health always has a political dimension, as seen at two recent international events - the World Health Summit in Geneva in May and the G7 Summit in the Bavarian Alps near Garmisch at the beginning of June. Report: Anja Behringer
“I am very concerned about the impact that Angelina Jolie has on the media,” Walter Rocca, professor of epidemiology and neurology at the Mayo Clinic in Rochester, Minnesota, stated. He wasn’t hinting to Jolie’s acting choices or waifish silhouette, but to the confusion surrounding her decision to remove her ovaries to prevent ovarian cancer. By Mélisande Rouger
Non-calcified arterial plaque is associated with diabetes, high systolic blood pressure and elevated 'bad' cholesterol levels in asymptomatic individuals, according to a new study published online in the journal Radiology.
Many NHS hospitals in the United Kingdom have established Rapid Access Chest Pain Clinics (RACPC) to work in tandem with them in offering primary percutaneous coronary intervention (PPCI) – the gold standard treatment for heart attacks – 24 hours a day. Report: Mark Nicholls
The German care system for patients with acute and unspecific chest pain is unique in Europe. The closely knit and countrywide network of accredited Chest Pain Units (CPUs) ensures fast and targeted diagnosis of acute cardiac events. The German CPUs may soon serve as a blueprint for other European countries. The German Cardiac Society (DGK) has already accredited the first institutions – others…
The importance of cardiac imaging is increasing, but nuclear medicine procedures are by no means obsolete, observes Okan Ekinci, during our EH interview with the Siemens Vice President for Healthcare Consulting & Clinical Affairs about the latest innovations for cardiology.
A British Society of Cardiac Imaging (BSCI) survey has confirmed that Toshiba’s Aquilion One scanner not only delivers exceptionally low radiation doses for cardiac CT, but also widens the scope of diagnostics in Cardiac CT because even patients with conditions eliminating them from a CT exam before this machine arrived can now be scanned.
Where some decry the commoditisation of radiology, Gabriel Krestin MD, sees an opportunity to redefine the profession, for radiologists to rise up from basement reading rooms to consult as equals with other medical specialists in multi-disciplinary conferences focused on patient care. ‘If we are going to think about the future, we should not be looking in a rear view mirror. We need to be open…
An independent survey conducted by the British Society of Cardiac Imaging (BSCI) yielded surprising results: Not only does Toshibas’ Aquilion ONE scanner deliver ultra-low radiation doses for cardiac CT, its next-generation PUREViSION detector also widens the scope of diagnostic cardiac CT. Radiologists agree that this innovative technology allows scanning of patients who previously would…
Twitter has broken news stories, launched and ended careers, started social movements and toppled governments, all by being an easy, direct and immediate way for people to share what's on their minds. Researchers from the University of Pennsylvania have now shown that the social media platform has another use: Twitter can serve as a dashboard indicator of a community's psychological well being…
Cardiovascular technology specialist Biotronik has launched a new series of single and dual chamber implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy defibrillators (CRT-Ds). ‘The Iperia/Itrevia/Inventra series gained CE approval in July 2014 and marked its first implantations worldwide in mid-July,’ the multinational biomedical technology firm reports.
What's the ideal solution for vulnerable plaque imaging? 'A non-invasive imaging procedure with high spatial and temporal resolution, and without radiation exposure, and which provides information on coronary plaque composition precisely and in series.' Report: Axel Viola
'In paediatric cardiology, echocardiography is the method of choice for preoperative diagnostic purposes,' explains Professor Dr Emanuela Valsangiacomo-Büchel, senior cardiologist and director of cardiovascular imaging at the University Children’s Hospital Zurich, Switzerland. Report: Axel Viola
Hybrid imaging is of little clinical value. PET-MRI, according to many experts, is the best clinical procedure to confirm coronary heart disease (CHD). Report: Axel Viola
Someone once described the fusion of positron emission tomography (PET) and magnetic resonance imaging (MRI) as a great technology looking for an application. Report: John Brosky
In the year of its 40th anniversary, Schiller proudly presents an algorithm which immediately and accurately localises coronary occlusions and provides early detection of STEMI. This algorithm is now integrated in the sophisticated touch ECG devices, the Cardovit MS line.
Evidence is scant on the cooling of comatose patients who have suffered cardiac arrest, stroke or traumatic brain injuries; nevertheless, new methods for cooling patients are continuously being developed.
The significant benefits of cardiac catherisation remain undisputed. However, cross-sectional imaging modalities are serious competitors when it comes to arriving at the right diagnosis.
The significant benefits of cardiac catherisation remain undisputed. However, cross-sectional imaging modalities are serious competitors when it comes to arriving at the right diagnosis.
The ‘Fire of Life’ developed by Schiller is an intuitive visual presentation of frequency-domain heart rate variability (HRV) that makes the assessment of 24-hour results fast and simple.
In uncomplicated stable angina cases no evidence suggests that angioplasty reduces heart attacks or death risks, Mark Nicholls reports
Imaging has progressed at vertiginous paces since X-rays were invented, not only as a diagnostic tool but also as an invaluable partner in the realm of non-invasive medical intervention.
No need to ask who was really shocked by the Halle Shock trial, followed by the multi-centre Shock II trial.
ECMO's role in a world's first cardiac procedure: Cardiac specialists in the UK have performed a world’s first operation on a 14-year-old boy suffering a severe heart condition. Mark Nicholls reports.
Whether mechanical, temporary cardiac assist systems should pulsate in the same way as a biological heart is a discussion topic, which raises the pulse rates amongst all those involved within the industry and in hospitals.
The heart is a structure in three dimensions and today we see it in three dimensions,’ Jose Luis Zamorano Gomez MD declared with satisfaction.
A cardiac surgeon, Wolfgang Goetz MD once stitched together custom aortic valves in the operating room. Today he is CEO of Transcatheter Technologies in Regensburg.
Clinicians and companies remain committed to a procedure that failed to demonstrate efficacy against a sham-control group in pivotal clinical trial
Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the number of unnecessary blood tests to assess symptoms of heart attack and chest pain and to achieve a large decrease in patient charges.
The UK’s first Specialist Emergency Care Hospital is on target to open for the first patients in 2015.
“The Saudi Arabian government’s response to the new virulent Middle Eastern Respiratory Syndrome (MERS) has recently been criticized, following high-level dismissals within the Saudi state healthcare service. Criticism has been leveled at the slowness of the government’s response to the outbreak, as well as in-fighting between physicians", says Andrew Thompson, Ph.D., GlobalData’s…
Ultrasound Contrast Agent SonoVue usable in case of recent acute coronary syndrome or clinically unstable ischaemic cardiac disease.
Bayer HealthCare has entered into a definitive agreement to sell its Interventional device business to Boston Scientific for $415 million (about EUR 300 million), including fees for transitional services. The sale will include the AngioJet (thrombectomy) and Jetstream (atherectomy) systems, and the Fetch2 Aspiration Catheter used in cardiology, radiology and peripheral vascular procedures.
Synchronised Cardiac Assist i-cor, which the company reports to be the first system that links mechanical circulatory support to the heartbeat.
A session at the forthcoming British Cardiovascular Society annual conference (2-4 June, in Manchester) will hear about the latest imaging techniques for acquired heart disease, with PET technology playing a key role in those advances.
The European Congress of Radiology (ECR), the biggest radiology meeting in Europe, was held March 6–10 in Vienna, Austria. Over 20,000 delegates from more than 110 countries attended the annual meeting of the European Society of Radiology (ESR), which took place for the 20th time at the Austria Center Vienna.
There is a wealth of information in every radiology exam, but even a phalanx of super-computers at the National Security Agency (NSA) could not extract it.
With low tube voltage, reduced radiation and contrast agent dose, the system delivers sufficient and meaningful data
In 2007, Sara Doll (Institute for Anatomy and Cell Biology, Heidelberg University) and Dr Frederik Giesel (Managing Senior Physician, Radiology Clinic, Department of Nuclear Medicine at Heidelberg University Hospital) initiated the development of virtual anatomy for a seminar aimed at students in the pre-clinical phase of their medical degree course.
Hybrid operating theatres that combine conventional surgical tools with image-guided diagnostic tools, allow cardiologists and cardiac surgeons to perform minimally invasive surgery (MIS).
Off-hour presentation and outcomes in patients with acute myocardial infarction: systematic review and meta-analysis
Since minimally invasive surgery (MIS) entered cardiac surgery in the mid-1990s it became unthinkable not to use this medical specialty. However, MIS procedures do not always result in the best outcome for patients.
Prevention Suite’s four combined imaging technologies enables practical pre-clinical assessment of cardiovascular disease risk .
Adding high quality, dynamic ultrasound for hybrid imaging enables clinicians to improve detection of a range of lesions or to intervene better for improved clinical outcomes. ‘We can no longer be fascinated with pictures; what we need is proof of the clinical benefit from tools and techniques,’ said Professor Jose Zamorano MD, Director of Cardiology at Ramón y Cajal University Hospital in…
Grandly announced, the da Vinci became the must-have of any self-respecting cardiac surgeon, only to sink into obscurity as quickly as it had risen to stardom. Once the wunderkind of robotic surgery, today this surgical system is merely collecting dust on many a hospital cupboard. A whole slew of methods and technologies were launched with varied fanfares over the past ten years. European…
A cardiac catheter is insufficient to evaluate the effects of a myocardial infarction. The size of the infarction and post-event cardiac muscle activity are crucial predictive parameters that determine therapy decisions
We must not forget that despite advances, cardiovascular disease remains the number one killer in Europe.
Since cardiac surgeon Adrian Kantrowitz, of the Maimonides Medical Centre, Brooklyn, first introduced intra-aortic balloon pulsation (IABP) into clinical practice in 1967 (Surg Clin North Am. 1969 Jun; 49 (3) :505 -11), the technique has been considered the method of choice for short-term mechanical cardiac support following a heart attack.
In 1839 Richard Thoma was the first to observe that arteries respond to flow: he identified a fundamental relationship between blood flow and arterial calibre.
The C-Pulse, manufactured by Australian-American company Sunshine Heart, Inc. is neither a pulsatile artificial heart nor one of the well-known non-pulsatile left heart support systems
‘Cardiology is one of the most innovative medical disciplines. Many modern technologies, such as catheterisations or imaging procedures, were triggered by cardiology,’ declared Professor Dr Gerald Maurer MD.
Death rates from cardiac disease have more than halved in many EU countries since the early 1980s, according to new research published in the European Heart Journal.
Each year the case grows stronger for transcatheter aortic valve replacement (TAVI). And it is only six years since the procedure was introduced in Europe.