Finding ways to target antibiotic-resistant bacteria is a scientific and medical priority. A consortium of researchers identified a compound capable of blocking a key protein for virulence, thus “disarming” the pathogenic bacteria.
Researchers have designed an artificial lateral (outer) meniscus that could help patients with chronic knee pain. The first patients have already undergone surgery and begun rehabilitation.
Researchers have developed ‘sponge-like’ microneedle patches that deliver bioactive ingredients and reduce inflammation in slow- and non-healing diabetic wounds.
Around 800,000 single-use theatre caps are consumed every year in Scottish hospitals. A new type of caps made from cellulosic fibre offer a sustainable alternative to traditional disposable options.
Researchers have created a mucus-based bioink which can be used for 3D printing lung tissue. This advance could one day help study and treat chronic lung conditions.
A new bioelectronic sensor enables continuous monitoring of bladder function. This could be a game-changer for people with paralysis, spina bifida, bladder cancer or end-stage bladder disease.
Researchers present new 3D-printable materials that can be easily monitored using X-ray or CT imaging. This has great potential to expand the possibilities of reconstructive and plastic surgery.
The field of lab-on-a-chip needs to meet important challenges around sustainability. This includes not only the development of smart analytical systems that are able to sense the changes that are occurring within the environment but also, more generally, the mitigation of single-use plastics in analysis and the use of low-power, recyclable microsystem technologies.
Under the impulse of the European Commission, the in vitro diagnostic industry is developing emerging technologies to implement sustainable practices in medical laboratories. As sustainability has been a growing priority of the European Union (EU) in the last decade, ‘the medical technology sector, particularly the IVD sector, must comply with European legislation in this field like all other…
Post-pandemic problems, ageing societies, the impact of climate change on human health: To find solutions for new and ongoing healthcare challenges, thinking outside the box is crucial. This year’s Medical Taiwan Health & Care Expo took this approach to heart: True to its motto “beyond healthcare”, the event showcased a wide range of innovative products, promising start-up presentations…
Missing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers’ technology for making time-released drugs.
A gel that combines both stiffness and toughness is a step forward in the bid to create biodegradable implants for joint injuries, according to new research from the University of British Columbia.
A new method for cheaply producing heart valves in the span of minutes shows great promise. The scientists describe the method as "a cotton-candy machine with a hair dryer behind it."
Surgeons will need to tackle three major challenges with the most potential to reduce major causes of death and improve access to surgical care, according to an international group of experts.
A team at the Finnish research institute VTT has created a biodegradable ECG patch, aiming to pave the way to a more sustainable future for wearable electronic devices.
Researchers at the University of Campinas and the Federal University of São Carlos in Brazil have developed an electrochemical sensor that detects Parkinson's disease at different stages.
Researchers have developed an inhalable powder that could protect lungs and airways from invasion from the coronavirus or flu viruses by reinforcing the body’s own mucosal layer.
During the Covid-19 pandemic, the use of these single-use diagnostics, or point-of-care tests has exploded. This is having major environmental consequences, experts point out.
Reseachers have developed a novel microneedle for injecting therapeutics into the eyes, potentially solving one of the major challenges of treating eye diseases.
Researchers have developed a biodegradable gel that can help to improve the delivery of cells into the living heart and could form a new generation of treatments to repair heart attack damage.
Researchers have developed 3D printed artificial heart valves designed to allow a patient’s own cells to form new tissue.
Wireless bioresorbable pacemaker bypasses need to extract non-biodegradable leads, eliminating additional risk to the patient.
A new biodegradable gel improves the immune system’s ability to keep cancer at bay after tumors are surgically removed.
3D-printed sugar models of dense and chaotic blood vessel networks near tumors could help future cancer treatments.
Contrast agents in the wastewater and power-hungry imaging systems: The eco-footprint of healthcare is huge, and radiology departments are among the main culprits. An expert panel at the ECR Overture explored ways to make the field “greener”.
A wireless sensor could offer doctors a way to monitor changes in brain chemistry without requiring a second operation to remove the implant.
A new kind of bone implant reduces the chance of infection, and therefore significantly decreases implant failure rates.
Engineers at MIT have developed a kind of surgical duct tape — a strong, flexible, and biocompatible sticky patch that can be applied to biological tissues and organs to help seal tears and wounds.
Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…
Researchers know that electricity can help speed up bone healing, but “zapping” fractures has never really caught on, since it requires surgically implanting and removing electrodes powered by an external source. Now, researchers at the University of Wisconsin–Madison have expanded on this principle and developed a device to speed up bone healing.
Researchers at Northwestern and George Washington (GW) universities have developed the first-ever transient pacemaker — a wireless, battery-free, fully implantable pacing device that disappears after it’s no longer needed. The thin, flexible, lightweight device could be used in patients who need temporary pacing after cardiac surgery or while waiting for a permanent pacemaker. All components…
Researchers funded by the British Heart Foundation (BHF) have developed biodegradable microspheres that can be used to deliver heart cells generated from stem cells to repair damaged hearts after a heart attack, in research presented at the British Cardiovascular Society conference.
Non-degradable prostheses for cardiovascular tissues can be used to replace heart valves and blood vessels, but they can’t stay in the body permanently. In two recent papers, researchers at the Eindhoven University of Technology (TU/e) in collaboration with a number of clinical partners, the Dutch Heart Foundation, and TU/e spin-off companies Suprapolix, Xeltis, and STENTiT have shown how…
In the past few decades, researchers have identified biological pathways leading to neurodegenerative diseases and developed promising molecular agents to target them. However, the translation of these findings into clinically approved treatments has progressed at a much slower rate, in part because of the challenges scientists face in delivering therapeutics across the blood-brain barrier (BBB)…
A bioactive polymer-ceramic composite for fixing implants and restoring bone defects in the skull was developed by an international group of materials scientists from the Russian National University of Science and Technology (NUST) MISIS Center for Composite Materials. An innovative composition of the material based on eggshell-derived bioceramic provides increased strength and biointegration of…
Johns Hopkins scientists report the successful use of nanoparticles to deliver gene therapy for blinding eye disease. A uniquely engineered large molecule allows researchers to compact large bundles of therapeutic DNA to be delivered into the cells of the eye.
Toshiba Corporation and a team led by Professor Yozo Nakazawa at the Department of Pediatrics, Shinshu University, have together developed a “tumor-tropic liposome technology” for gene therapy. The technology uses unique, nano-sized biodegradable liposomes developed by Toshiba to accurately and efficiently deliver therapeutic genes to targeted cancer cells, and achieves safer gene delivery…
The drug nimodipine could prevent nerve cells from dying after brain surgery. Pharmacists at Martin Luther University Halle-Wittenberg (MLU), in cooperation with neurosurgeons at University Hospital Halle (Saale) (UKH), have developed a new method that enables the drug to be administered directly in the brain with fewer side effects. Their findings were published in the European Journal of…
A research team co-led by a scientist at City University of Hong Kong (CityU) has discovered a new, non-invasive way to detect early-stage Alzheimer’s disease, helping patients get the necessary treatments around 10 years before any symptoms appear. In collaboration with Johns Hopkins University in the US, Dr Kannie Chan Wai-yan, Associate Professor in the Department of Biomedical Engineering…
With the help of a 3D printed salt template, ETH researchers from ETH Zurich have succeeded in producing magnesium scaffolds with structured porosity that are suitable for bioresorbable bone implants. For the treatment of complex bone fractures or even missing bone parts, surgeons typically deploy metal implants. In this context, an attractive alternative to the traditional materials like…
Targeting medical treatment to an ailing body part is a practice as old as medicine itself. A Band-Aid is placed on a skinned knee. Drops go into itchy eyes. A broken arm goes into a cast. But often what ails us is inside the body and is not so easy to reach. In such cases, a treatment like surgery or chemotherapy might be called for. A pair of researchers in Caltech's Division of Engineering and…
Melanin protects our skin from the sun’s damaging rays by absorbing light energy and converting it to heat. This could make it a very effective tool in tumor diagnosis and treatment, as demonstrated by a team from the Technical University of Munich (TUM) and Helmholtz Zentrum München. The scientists managed to create melanin-loaded cell membrane derived nanoparticles, which improved tumor…
A new device developed by Stanford University researchers could make it easier for doctors to monitor the success of blood vessel surgery. The sensor, detailed in a paper published in Nature Biomedical Engineering, monitors the flow of blood through an artery. It is biodegradable, battery-free and wireless, so it is compact and doesn’t need to be removed and it can warn a patient’s doctor if…
Many people who are diagnosed with cancer will undergo some type of surgery to treat their disease — almost 95 percent of people with early-diagnosed breast cancer will require surgery and it’s often the first line of treatment for people with brain tumors, for example. But despite improvements in surgical techniques over the past decade, the cancer often comes back after the procedure. Now,…
A material based on a natural product of bones and citrus fruits, called citrate, provides the extra energy stem cells need to form new bone tissue, according to a team of Penn State bioengineers. The new understanding of the mechanism that allows citrate to aid in bone regeneration will help the researchers develop slow-release, biodegradable citrate-releasing scaffolds to act as bone-growth…
Nanosystems that deliver anticancer drugs or imaging materials to tumours are showing significant progress, particularly those that respond to tumour-related stimuli, according to a review published in the journal Science and Technology of Advanced Materials. However, further research is still required to make sure these delivery systems are stable, non-toxic and biodegradable. Nanocarriers…
Until now ulcers inside the mouth have been treated using creams or mouthwashes for the whole mouth. A new biodegradable patch administers steroids directly to oral ulcers and forms a protective barrier. Scientists from the University of Sheffield’s School of Clinical Dentistry, working in close collaboration with Dermtreat A/S from Copenhagen, have developed a unique patch using special…
Engineers at the University of Connecticut (UConn) have created a biodegradable pressure sensor that could help doctors monitor chronic lung disease, swelling of the brain, and other medical conditions before dissolving harmlessly in a patient’s body. The UConn research is featured in the current online issue of the Proceedings of the National Academy of Sciences. The small, flexible sensor is…
For many of us, a flu shot is a fall routine. Roll up a sleeve, take a needle to the upper arm and hope this year’s vaccine matches whichever viruses circulate through the winter. The most common method to make that vaccine is now more than 70 years old. It requires growing viruses in special, pathogen-free chicken eggs. It’s not a quick and easy manufacturing process. And, at best, it…
There hasn't been a gold standard for how orthopedic spine surgeons promote new bone growth in patients, but now Northwestern University scientists have designed a bioactive nanomaterial that is so good at stimulating bone regeneration it could become the method surgeons prefer.
A Northwestern University research team has developed a 3D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic “bone” material, whose shape can be easily customized, one day could be especially useful for the treatment of bone defects in children.
A small device implanted under the skin can improve breast cancer survival by catching cancer cells, slowing the development of metastatic tumors in other organs and allowing time to intervene with surgery or other therapies. These findings suggest a path for identifying metastatic cancer early and intervening to improve outcomes.
With a goal of treating worn, arthritic hips without extensive surgery to replace them, scientists have programmed stem cells to grow new cartilage on a 3-D template shaped like the ball of a hip joint. What’s more, using gene therapy, they have activated the new cartilage to release anti-inflammatory molecules to fend off a return of arthritis. The technique was demonstrated in a collaborative…
To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3D printer. That’s the recipe for success reported by researchers at The Johns Hopkins University.
By using drug delivery vehicles, so-called nanocarriers, pharmaceuticals reach the diseased area in the body. There they accelerate the healing process. But in order to prevent them from getting ingested by phagocytes, the surfaces of the nanocarriers are typically coated with the biocompatible synthetic polymer poly(ethylene glycol) (PEG). Scientists at the Mainz University Medical Center and…
A new injectable “biogel” is effective in delivering anti-cancer agents directly into cancerous tumours and killing them. This technology, developed by researchers at the University of Montreal Hospital Research Centre (CRCHUM), has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionize treatment for many forms of cancer.
Regenerative medicine uses cells harvested from the patient’s own body to heal damaged tissue. Fraunhofer researchers have developed a cell-free substrate containing proteins to which autologous cells bind and grow only after implantation.
Bioplastics made from protein sources such as albumin and whey have shown significant antibacterial properties, findings that could eventually lead to their use in plastics used in medical applications such as wound healing dressings, sutures, catheter tubes and drug delivery, according to a recent study.
A novel, entirely biodegradable device has been successfully implanted in a blocked artery patient needing a percutaneous coronary intervention
Stent fever, first diagnosed in 1997, has been spreading throughout the medical world – fuelled by new technologies, says Holger Zorn
France – Re-opening clogged arteries with metal stents has proved a life-saver for a majority of patients with coronary disease. Yet the high rates of complications and mortality for patients with diabetes following a percutaneous coronary intervention (PCI) continue to baffle cardiologists. Report: John Brosky
Drug-eluting stents to treat narrowed coronary vessels met with sensational success, and then things became rather quiet. Now, two new developments from Cordis and Biotronik are being tested at Essen University Hospital, Germany. We asked Professor Holger Eggebrecht, head of the hospital’s cardiac catheter lab, why these new models look important.
The landmark achievements in interventional cardiology that are rapidly advancing minimally invasive surgeries (MIS) on a beating heart were demonstrated during a Paris course on revascularisation (EuroPCR), the annual meeting of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).
Hot topics to be covered during the EuroPCR Forum sessions are the challenging implementation of the best standard of care for STEMI patients throughout Europe (with the timely use of stents), the introduction of transcatheter aortic valve implantation (TAVI) in clinical practice and the challenges related to bifurcation treatment options.
During a gathering of clinicians, scientists and economists at this year's Medical Technology Congress (Treffpunkt für Medizintechnik) held in Berlin's Charité Hospital, all 17 lectures focused on cancer treatments. Bettina Döbereiner reports
An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area.
The multichannel tips are also packaged in new cases that simplify handling and storage and facilitate recycling.
An interdisciplinary researcher team from the University of Sheffield has developed an ultra-fine, 3-dimensional scaffold to regenerate skin for wound healing. It dissolves after integrating in the wound and might provide a more safer way of treating injuries.
The UK's MRSA rates have been declining since 2006 — and this year could be 50% lower than in 2004. This increasing control over dangerous pathogens has not been achieved without considerable hospital staff efforts, relentless public and government pressures on them, and in-house malcontent about the out-sourcing of cleaning work. Given the cost of nosocomial infections to patients, the NHS…
Recent studies show that drug-eluting-stents perform superior than bare metal stents in the treatment of high-risk cardiac patients. At ComPaMED 2007, the Germany based company HEMOTEQ, leading designer and manufacturer of ultra-thin coatings for medical devices, presented their solutions for customized coating of stents.
Coronary stents provide wall wrapping of dissection, prevent elastic recoil, and reduce restenosis after percutaneous transluminal coronary angioplasty. In addition, drug eluting stents loaded with antiproliferative agents inhibit intimal hyperplasia and offer a further reduction of restenosis.
Cancer can be tackled with a combination of drug and genetic therapies, so that the effectiveness of individual treatments are enhanced.
A new biodegradable solution has stopped bleeding in animals' wounds within seconds, according to a report in the journal Nanomedicine.
Austria - A call for the EU and national governments to establish and extend a legal framework for environmental standards in society and healthcare facilities was made by the organisers of `CleanMed Europe´, the first European conference to focus on sustainable healthcare products and practices.