To take cell therapy in regenerative medicine to a new level, experts consider 3D bioprinting a key technology. However, there are still quality issues that need to be overcome to achieve this.
Rsearchers developed a novel bioelectronic device that taps into the natural electrical activity of certain bacteria found on our skin, paving the way for a drug-free approach to managing infections.
Smart catheters, smart diapers or wound dressings: a new approach to wireless biosensors from Malmö University opens up options for more patient-controlled ways of infection detection.
Chronic wounds in diabetes patients are often slow to heal, which can lead to serious infections and even limb amputation. Now, researchers propose to address this with a magnetic wound-healing gel.
A newly discovered mechanism involving exosomes can drive inflammation and impair healing of wounds in diabetes patients, according to a new study led by University of Pittsburgh and UPMC researchers.
A new kind of smart bandage developed at Caltech may make treatment of chronic wounds - for example caused by diabetes - easier, more effective, and less expensive.
Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).
Scientists have discovered a way to train healthy immune cells to acquire the skills of some tumor cells for a good purpose: to accelerate diabetic wound healing.
Researchers at Nottingham Trent University and Nottingham University Hospitals NHS Trust have developed a new biosensor capable of accurately monitoring the condition of a chronic wound.
Over the past years, the world has been transforming into a post-Covid era. Taiwan has stepped up to the challenge on innovation and taking the advancement of digital healthcare to a whole new level.
Light therapy may accelerate the healing of skin damage from radiation therapy by up to 50%, according to a recent University at Buffalo-led study.
Scientists at Queen’s University Belfast have invented a tiny indicator that changes colour if a patient’s wound shows early signs of infection.
A research team led by Professor Lim Chwee Teck from the National University of Singapore’s (NUS) Department of Biomedical Engineering and Institute for Health Innovation & Technology (iHealthtech), in collaboration with clinical partners from Singapore General Hospital, has developed a smart wearable sensor that can conduct real-time, point-of-care assessment of chronic wounds wirelessly…
Researchers at RMIT University in Australia have developed smart wound dressings with built-in nanosensors that glow to alert patients when a wound is not healing properly. The multifunctional, antimicrobial dressings feature fluorescent sensors that glow brightly under UV light if infection starts to set in and can be used to monitor healing progress.
New coatings on implants could help make them more compatible. Researchers at the Martin Luther University Halle-Wittenberg (MLU) have developed a new method of applying anti-inflammatory substances to implants in order to inhibit undesirable inflammatory reactions in the body. Their study was recently published in the "International Journal of Molecular Sciences".
Stevens Institute of Technology has signed an exclusive licensing agreement with Bonbouton, giving the company the right to use and further develop a graphene sensing system that detects early signs of foot ulcers before they form, so diabetic patients can access preventative healthcare and manage their health.
Healthcare is going digital worldwide at an incredibly rapid pace. More and more applications for prevention, diagnostics and therapy are being made into apps (with matching hardware) for smartphones and tablets or are even available as wearables for direct use on the body. Digitalisation is also striding forward in Germany, where doctors, therapists and patients still take a fairly analogue…
Non-alcoholic fatty liver disease is among the most common chronic hepatic disorders in Western industrial countries and the rate is also rapidly rising in newly industrialized countries. Experts estimate that about 30 to 40 percent of the population worldwide develop this liver condition. In the United States, this disease is well on the way to becoming the most frequent indication for liver…
Many methods to treat current or chronic wounds are available. However, the differences in general conditions prevailing in hospital, or for out-patient care, make effective therapy more difficult. Each patient also has other preconditions for healing. Improved communication between everyone involved in the treatment would benefit patients. We see a lot of progress with the issue of “wounds”,…
Skin has a remarkable ability to heal itself. But in some cases, wounds heal very slowly or not at all, putting a person at risk for chronic pain, infection and scarring. Now, researchers have developed a self-powered bandage that generates an electric field over an injury, dramatically reducing the healing time for skin wounds in rats. They report their results in ACS Nano. Chronic skin wounds…
A material based on a natural product of bones and citrus fruits, called citrate, provides the extra energy stem cells need to form new bone tissue, according to a team of Penn State bioengineers. The new understanding of the mechanism that allows citrate to aid in bone regeneration will help the researchers develop slow-release, biodegradable citrate-releasing scaffolds to act as bone-growth…
Point-of-care ultrasound (POCUS) has become an important adjunct to clinical diagnosis and procedural guidance in the Pediatric Emergency Department (PED), supported by literature demonstrating that its use can improve patient safety and expedite life-saving care. POCUS further helps to reduce costs and children’s exposure to ionizing radiation. Not only is POCUS ideally suited for…
Macrophage cells routinely remove dead or dying cells to maintain the body homeostasis. Such removal becomes crucial after serious injury, especially the repair of dead heart muscle after a heart attack. University of Alabama at Birmingham researchers have preliminary data, with cultured cells or diabetic hearts, that diabetes impairs this removal of dead heart-muscle cells. They believe this…
Smith & Nephew, the global medical technology business, announces the European launch of MolecuLight i:X, the easy to use, handheld imaging device that instantly measures wound surface area and visualises the presence and distribution of potentially harmful bacteria in wounds. Currently wound assessments are made with the naked eye which can lack the accuracy required to most effectively…
Overcrowding in healthcare systems has become a worldwide phenomenon with regional influences related to the different healthcare structures in different countries. A recent BBC analysis (February 2017) showed that overcrowding afflicted 9 out of 10 NHS hospitals this winter, with 23 declaring ‘black alerts’, as other European hospitals face similar ‘care crises’, especially member states…
Electrospun materials bring a spark of hope to a cardiovascular landscape darkened by setbacks for reabsorbable stents. It was famously said that implanting a device in a person to cure a disease is to implant a new disease. Simply put, the human body will continually fight against foreign materials, leading to chronic inflammations or repeated interventions.
Chronic lung infections caused by the bacterium Pseudomonas aeruginosa require complex and, in most cases, long-term treatment with antibiotics—new medication is badly needed.
Surgeons at Johns Hopkins Medicine report that their first series of a minimally invasive procedure to treat chronic pancreas disease, known as severe pancreatitis, resulted in shorter hospital stays, less need for opioids and fewer complications, compared with standard surgical approaches.
A certain immune reaction is the key, not to slowing atherosclerosis like cholesterol-lowering drugs do, but instead to reversing a disease that gradually blocks arteries to cause heart attacks and strokes. This is the finding of a study in mice led by researchers at NYU Langone Medical Center.
Clinicians around the world have long suspected that bacteraemia due to Staphylococcus aureus has a worse outcome in women compared to men, but direct evidence has been elusive. A study just published confirms that significantly more women than men diagnosed with Staphylococcus aureus bacteraemia (SAB) – a blood infection of the common bacteria – die within 30 days.
Australian researchers develop a new technique that tricks bacterial biofilms into dislodging from their protective matrix, making them vulnerable to treatment with antibiotics.
The European Society of Clinical Microbiology and Infectious Disease (ESCMID) advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms, which contribute to antimicrobial resistance.
Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.
Researchers from the University of Sheffield’s Department of Biomedical Science discovered the ultrasound transmits a vibration through the skin and wakes up cells in wounds helping to stimulate and accelerate the healing process.
Many people suffer from skin disorders. Open wounds are a particularly acute problem, especially among the elderly. PlasmaDerm, a new medical technology solution, uses plasma to facilitate faster healing of wounds.
Electricity is not the only thing that should come out of an electrical socket; ideally so should cold atmospheric plasma, according to Dr Georg Daeschlein, at the Dermatology Department, University of Greifswald, who has investigated its medical properties for years. Report: Ralf Mateblowski
‘Better hygiene’ is the frequently and loudly recommended panacea in the intensifying struggle against hospital-acquired infections (HAIs). However there are currently no evidence-based studies that evaluate the efficacy of additional hygiene measures.
Since minimally invasive surgery (MIS) entered cardiac surgery in the mid-1990s it became unthinkable not to use this medical specialty. However, MIS procedures do not always result in the best outcome for patients.
The world’s first point-of-care wound test, unveiled last November at the Wounds UK conference, is now used by the National Health Service (NHS) -- and internationally.
Every year, around 80,000 lower extremities in Europe have to be (partially) amputated as a result of peripheral arterial occlusive disease (PAOD). Half of the affected patients die within five years of the amputation.
Every year in Germany, four million wounds leave a legacy of 30 000 amputations and six billion Euros in treatment costs. These shocking figures drew wound experts to the Pflege Kongress 2012 (2012 Care Congress) held in Berlin.
Italy is a front runner in diabetic foot revascularisation. Among the country’s pioneers is Professor Roberto Gandini, at the Diagnostic Imaging and Interventional Radiology Department, University of Tor Vergata in Rome, who has developed and improved new technical options in peripheral vascular disease intervention, a technique that now saves about 92% of patients from major amputations due…
From 16 - 19 November 2011, the attention of health and medical care professionals from around the world will once again focus on Düsseldorf, as the world's largest medical trade fair, MEDICA 2011, World Forum for Medicine, and COMPAMED 2011, High tech solutions for medical technology, the leading international trade fair for the suppliers market in medical manufacturing, get underway.
It turns out to be difficult to find out exactly how much a child who cannot yet speak suffers after a surgical operation. Researchers at the University Hospital of La Paz, in Madrid, have validated the 'Llanto' scale, the first, and only, tool in Spanish which measures infant pain rapidly and simply.
Cold plasma jets could be a safe, effective alternative to antibiotics to treat multi-drug resistant infections, says a study published this week in the January issue of the Journal of Medical Microbiology. The team of Russian and German researchers showed that a ten-minute treatment with low-temperature plasma was not only able to kill drug-resistant bacteria causing wound infections in rats but…
Quality in wound care no longer centres only on a successful healing process but is taking a more holistic, patient-orientated approach. Wounds cause pain, impair quality of life, and make treatment far more complex for medical teams. Approaches that facilitate a painless change of dressings and less wound trauma are therefore welcome – and advancing.
Scientists have determined that chronic wounds might have trouble healing because of the actions of a tiny piece of a molecular structure in cells known as RNA. The Ohio State University researchers discovered in a new animal study that this RNA segment in wounds with limited blood flow lowers the production of a protein that is needed to encourage skin cells to grow and close over the sore.
The new Traumastem biodress is the world’s first oxidised cellulose preparation to treat acute and chronic wounds, its Czech manufacturer Bioster a.s. reports.
For the past 30 years, in the former USSR and Russia, laser medicine has been actively developed and regular annual conferences have opened new avenues for its use by the country's doctors.
Full automation has now become the gold standard for clinical laboratories. Without hospital microbiology labs, which according to the Centres for Disease Control deal with 1.7 million infections and 99,000 associated deaths annually in the US alone, the growing threat of community-acquired and nosocomial infections could prove insuperable.
In recent years wound management has been primarily nurse-led, and not benefited from a multi-disciplinary approach. This must change, said Madeleine Flanagan, Principal Lecturer at the University of Hertfordshire's school of Post Graduate Medicine in the faculty of health and human science, where she runs the MSc in Dermatology and an MSc in Skin Integrity; she is also Principal of the European…
The content of training courses on wound care and risk assessment would have one believe that chronic wounds are merely a marginal problem of medical care. The opposite is the case. The number of chronic wounds, and therefore cost of care, are on the increase. Where might the problems and sources of these errors lie?
According to ECD statistics for Europe, three million cases of nosocomial infections occur annually, and 50,000 are fatal. Evelina Tacconelli MD PhD (below) is Assistant Professor of Infectious Diseases at the Università Cattolica Sacro Cuore in Rome, Italy. Her scientific focus is on epidemiology, clinical and therapeutic aspects of nosocomial infections and infection control policies aimed to…
A wound compress is being developed at the Hohenstein Institute in Boennigheim, Germany, that could pave the way for new treatment opportunities. The new wound compress would integrate and continually deliver effective ingredients on the basis of nanosol technology. The technique speeds up healing, simplifies treatment and reduces the amount of time required for care.
When it comes to chronic wound care, says Professor Heinz J Janssen of the Institute for Health and Nursing Economics (IGP) at Bremen University of Applied Sciences, cost effectiveness and quality are not contradictions.
The COMPAMED, the leading specialist international trade fair for suppliers to the medical manufacturing market, is held parallel to the MEDICA, the world's largest medical trade fair, each year and showcases the dynamism and innovative power of the medical technology sector. The COMPAMED 2008, High tech solutions for medical technology, will, with around 500 exhibitors from 30 nations, once…
An interdisciplinary researcher team from the University of Sheffield has developed an ultra-fine, 3-dimensional scaffold to regenerate skin for wound healing. It dissolves after integrating in the wound and might provide a more safer way of treating injuries.
Little research has been carried out into new therapies for wound healing. As chronic wounds tend to be classed as side effects of other diseases, e.g. diabetes, they are often treated as trivial. However, the body's capacity to heal itself often does not set in for weeks.
The recently launched KFH Novo from Kingfisher Healthcare (KFH) is a non-invasive medical device that utilises Bio-Electric Stimulation Therapy (BEST) to deliver extremely low levels of current to chronic wounds. This does not interfere with standard conventional therapy; the electrodes are placed some way from the wounds, beyond the normal treatment areas.
Process optimisation concerns all primary and secondary processes in a hospital. Case management is a tool that supports the implementation of comprehensive optimisation efforts.
Hair follicles, long disregarded by researchers, except in the cosmetic industry, may turn out to be `the fountain of youth´, according to Andreas Emmendörffer, CEO of German biotech firm Euroderm.
Marie-Luise Müller is President of Deutscher Pflegerat e.V. (German Care e.V) Council, and Chair of its Congress, which was held alongside the Capital Congress on Medicine and Health 2008 in Berlin this June. During our interview, we asked her whether there is too little German medical and political recognition of nursing as a health profession in its own right.
Born in 1891, Canadian Sir Frederick Banting was destined to become a medical scientist and Nobel Prize winner for work that led to the discovery of insulin. World Diabetes Day, held on his birthday, aims to sensitise the public - including potential patients - to this condition. Worldwide, around 245 million people suffer Diabetes mellitus. With 5.3 million of them in Germany, the country's…
Could a computer programme help? Recommendations of the Robert-Koch-Institute
Every day, patients are admitted to surgeries, hospitals and outpatient clinics with chronic wounds. Careful inspection gives a wound therapist clues to the appropriate primary care required even before further diagnostic procedures are carried out. So what do the clinical signs and symptoms tell us? Report: Heidi Heinold
Rationale and effectiveness in the non-healing diabetic foot ulcer patient. By Peter HJ Mueller and Robert A Warriner III
An application report by assistant plastic surgeon Thomas Aigner, and F Weyer, of the Department of Plastic, Aesthetic and Reconstructive Surgery, at St. Polten Hospital, Austria
Paul E Pepe MD MPH FACEP FCCM, Professor of Medicine, Surgery, Public Health and Chair, Emergency Medicine, The University of Texas Southwestern Medical Centre and the Parkland Health and Hospital System (TSMC&PHHS), Dallas.