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News • Research on physical conditions
Exploring the link between obesity and cancer risk
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
Ordering preoperative breast MRI exams of diagnosed breast cancer patients used to be controversial: Did they aid surgical planning better than the combination of mammography and breast ultrasound? Or did their findings cause overtreatment, specifically mastectomy, when breast-conservation surgery would have sufficed? New research has now settled the issue.
Breast MRI is increasingly being used as a primary breast cancer screening exam for young women. It brings benefits in women with dense breasts, who are at an elevated risk of developing breast cancer. The technique is also being ordered as a supplemental screening exam following mammography or breast ultrasound for women of all ages at high risk. But use of breast MRI as a screening tool is…
Bone fractures caused by osteoporosis are a common major global health risk. The International Osteoporosis Foundation (IOF) reports that one in three women over the age of 50 will sustain a potentially life-threatening fragility fracture in their remaining lifetimes. Early diagnosis and proactive treatment to keep bones healthy, including prescription medication and lifestyle changes, has the…
Researchers and clinicians at Washington University in St. Louis found a way to improve diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes.
New research led by Brigham and Women’s Hospital unveils that women who struggle with getting enough sleep might be at greater risk of developing hypertension, or high blood pressure.
Where are the beginnings of breast cancer? A team of researchers at Kyoto University has revealed the mechanism by which breast cancer is formed in the cells of mammalian epithelium.
Endometriosis, which can cause debilitating pain each menstrual cycle, as well as infertility, is often misdiagnosed and misunderstood. An expert from Yale Medicine sheds light on the condition.
A trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms.
Women with high-risk breast lesions (HRLs) and no family history of breast cancer or BRCA mutations are generally considered to be at moderate risk of developing breast cancer. Breast cancer screening guidelines suggest breast MRI be considered as a supplement to mammography. But is this expensive exam necessary?
What if a test analysing cervical cells from a gynaecological swab could be used to detect four different female cancers at an early stage and also predict cancer risk over a healthy woman's lifetime? Researchers at the EUTOPS Institute in Innsbruck, Austria, are developing tests to do just that for breast, ovarian, cervical, and endometrial cancer detection.
Not just uncomfortable, but hard on the heart: Accumulating research suggests a link between hot flashes during the menopause and cardiovascular disease risk in women.
The hearts of men and women are different – while this insight has been established for quite some time now, it might even surprise cardiologists just how deep these differences really run. In her presentation at this year’s ESC, Diana Bonderman, MD, gave a comprehensive roundup on sex differences in risk factors and subtypes of heart failure.
The critical times in a woman’s life of pregnancy and the menopause – and their relation to heart health – is explored at the ESC. The defined field of gender-specific cardiology is becoming an increasingly important area of focus, experts say.
Changes in areas of the brain associated with emotion have been identified in people with Takotsubo syndrome, sometimes known as broken heart syndrome, according to new research.
A new study has found that women’s health research remains disproportionately focused on the reproductive years, with few articles on the major causes of illness and death in women.
Many women feel they are not being listened to about their health needs – and experience a lack of empathy around problems relating to menstruation, fertility, childbirth and menopause.
In the emerging era of personalized medicine, risk-based breast cancer screening protocols may be better than the one-size-fits all approach. It’s time to consider adopting them, Jack Cuzick, Ph.D., said in the President’s Address of the 2021 Society of Breast Imaging/American College of Radiology Breast Imaging Symposium.
Beckman Coulter announced the launch of an AMH test that uses a validated cut-off to aid in the assessment of poor ovarian response. This new assay helps clinicians predict poor ovarian response in those who plan to undergo controlled ovarian stimulation as part of an in vitro fertilisation (IVF) protocol.
The length of the female reproductive period (the time from the onset of menses to the final menstrual period) has important health implications. A new study compared the length of reproductive periods for women with type 1 diabetes with women without diabetes to confirm the effect diabetes has on the female reproductive system. Study results are published online in Menopause, the journal of The…
Pregnancy complications and early menopause increase women’s future risk of heart disease. Cardiologists, gynaecologists and endocrinologists recommend how to help middle-aged women prevent later heart problems in a European Society of Cardiology (ESC) consensus document published in European Heart Journal, a journal of the ESC.
Smoking is strongly linked to lower use of cancer screening services by women, and more advanced disease once cancer is diagnosed, new research reveals. Tobacco use is falling in many parts of the world, but it’s falling less rapidly among women than it is among men. And lung cancer remains the leading cause of cancer death among women, say the researchers. The evidence also suggests that women…
A growth hormone called insulin-like growth factor-1 (IGF-1) is likely to play a role in the development of breast cancer, according to new research published in the leading cancer journal Annals of Oncology. IGF-1 is already known to encourage the growth and proliferation of cancer cells. Now, two analyses of information from several hundred thousand women enrolled in the UK Biobank study have…
Eric Prossnitz, PhD, from the University of New Mexico Health Services and his team hope to help 93 million obese Americans fight their fat. In a paper published in Science Translational Medicine, they reported that G-1, a cancer-fighting compound they discovered some years ago, reduces fat in obese mice. Although G-1 is currently in phase 1 clinical trials for cancer, Prossnitz and his team are…
During its latest keynote presentation, tech giant Apple announced cooperations for health studies. The latest model of their smartwatches are to be key in their execution. Apple announced the three medical studies in partnership with leading US academic and research institutions.
New research at the University of Kentucky has confirmed that the presence of XX sex chromosomes increases the amount of fat circulating in the blood, which leads to narrowing of the arteries and ultimately a higher risk of heart attacks and coronary artery disease. The research was published in Nature Communications. The leading cause of death in women is coronary artery disease (CAD), but women…
Interventional cardiologists have been aware of the value of intracoronary (IC) imaging in clinical practice for more than twenty years. However, recent developments and improvements in modalities and software have enabled huge strides in its range and scope for both diagnostic assessment and in percutaneous coronary interventions. Imaging options now include intravascular ultrasound (IVUS),…
Family planning for women might one day be as simple as putting on an earring. A report published recently in the Journal of Controlled Release describes a technique for administering contraceptive hormones through special backings on jewelry such as earrings, wristwatches, rings or necklaces. The contraceptive hormones are contained in patches applied to portions of the jewelry in contact with…
Researchers have created a new machine learning software that can forecast the survival rates and response to treatments of patients with ovarian cancer. The artificial intelligence software, created by researchers at Imperial College London and the University of Melbourne, has been able to predict the prognosis of patients with ovarian cancer more accurately than current methods. It can also…
In general, women who have had children have a lower risk of breast cancer compared to women who have never given birth. However, new research has found that moms don’t experience this breast cancer protection until many years later and may face elevated risk for more than 20 years after their last pregnancy. Scientists at the National Institutes of Health, along with members of the…
Weak, easily broken bones are an epidemic in the United States. They’re often tied to osteoporosis, a disease that causes bones to degenerate over time. This makes them less flexible, more brittle, and easier to break. According to the International Osteoporosis Foundation, more than 44 million Americans aged 50 and older either have or face the threat of developing osteoporosis due to low bone…
Belly fat affects the odds of women surviving kidney cancer but not men, according to a new study by researchers at Washington University School of Medicine in St. Louis. Half of female kidney cancer patients with substantial abdominal fat at the time of diagnosis died within 3 1/2 years, while more than half of women with little belly fat were still alive 10 years later, the researchers found.…
Two new systems developed by Hologic Inc. recently received the European CE Mark: The MyoSure Manual and the Brevera Breast Biopsy System with CorLumina Imaging Technology.
A new genetic test to assess breast cancer risk in women who have a family history of the disease could be introduced into clinical practice in the UK within the next few months. Devised at Manchester University NHS Foundation Trust (MFT) and the University of Manchester, researchers believe the test for high-risk groups could also help reduce the number of women needing to have surgery to remove…
Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team of investigators published in the New England Journal of Medicine. Standard treatment for estrogen receptor-positive, or ER-positive, breast cancer includes five years of the endocrine-based…
The taller you are, the more likely you may be to develop blood clots in the veins, according to new research in the American Heart Association journal Circulation: Cardiovascular Genetics.
Many women are turning to egg freezing to promote fertility, but what happens when it isn't an option because of special medical or other conditions? And, what option is there for women who want to preserve hormonal function, not just fertility?
‘Today Vienna is one of the top addresses with regard to breast cancer research,’ Professor Michael Gnant proudly reports – and he certainly knows what he is talking about.
Starting immediately, Sectra and private care provider Unilabs will offer preventive bone health testing for individuals with risk factors for osteoporosis, thereby enabling measures to be taken to reduce the risk of fractures. The analysis technology to be used by Unilabs will be provided by Sectra. One in two women in Sweden will suffer from a fracture due to osteoporosis, making osteoporosis…
Many breast tumors grow in response to female hormones, especially estrogen. Drugs that reduce estrogen levels in the body often are effective in reducing tumor size and preventing recurrence of the cancer. But some tumors become resistant to these therapies and continue to grow and spread.
It’s well known that cardiovascular disease (CVD) is the leading cause of death in the UK and worldwide. In the UK it is responsible for more than 73,000 deaths annually, affecting 1 in 6 men and 1 in 10 women. With the emergence of such startling statistics, this begs the question, why do routine cholesterol tests still rely on the basic biomarkers high density lipoprotein (HDL), low density…
In a discovery that could lead to more targeted and effective treatments for certain lung and prostate cancers, researchers at the University of Virginia School of Medicine have identified two new cancer-causing gene mutations – mutations that may be particularly susceptible to cancer-fighting drugs already approved by the federal Food and Drug Administration. One of the gene mutations also may…
Among new medical imaging innovations is a phase-contrast x-ray technique to bring greater precision to breast cancer assessment and improve biopsy diagnostics. EH asked research pioneer Professor Marco Stampanoni, a key figure in the development of this technique, to explain how it works. Report: Sascha Keutel
Expert estimates suggest that women eating more poultry, fish, nuts and legumes and less red meat might have lower risk.
New Assay Is First to Standardize to World Health Organization’s 5th International Standard for Chorionic Gonadotropin
Scientists from the German Cancer Research Center (DKFZ) in Heidelberg have been the first to prove that genetic and environmental risk factors for breast cancer do not act independently of each other.
You won't find a single new machine among the novel technology shaping radiology. Instead software, not hardware, is the key that is opening new frontiers.
‘The egg timer test’ is widely used to help determine how long a woman can expect to remain fertile. Lately it has shown even greater potential for clinical use as a biomarker for ovarian viability.
Norwegian studies indicate that people with osteoporosis have a greater risk of developing cardiovascular disease, and vice versa. Now researchers believe they have found a biological system that may influence both disease processes.
Digital mammograms deliver an average of 22% less radiation than film mammograms, according to a study partially funded by the National Cancer Institute and published in the American Journal of Roentgenology, Reuters reports. For the study, researchers analyzed the results of the 2005 Digital Mammographic Imaging Screening Trial involving 49,528 women. That trial found that digital mammograms…
ECCO 15 – ESMO 34, the joint congress of the European CanCer Organisation (ECCO) and the European Society for Medical Oncology (ESMO), is Europe’s largest oncology meeting; the event drew to Berlin 15,000 participants from 120 countries this September, when more than 2,000 presentations were made. Among the presentations on prevention, treatment and survivorship, proteomics, biomarkers,…
The breast cancer risk of women who are regularly physically active in the postmenopausal phase is reduced by about one third compared to relatively inactive women, according to a study conducted by the German Cancer Research Centre (Deutsches Krebsforschungszentrum, DKFZ) and the University Hospitals of Hamburg-Eppendorf.
Women who survive breast cancer for at least five years have a 89% chance that it will not recure. But those, who are still suffering and on endocrine treatment are likely to get arthralgia and arthritis.
As rocks keep the secrets of the earth, bones might keep those of the body. A new study that will be publish in the September 1, 2008 issue of CANCER suggests, that factors responsible for higher bone mineral density might also lead to higher risk of breast cancer.
Brenda Marsh reports on the country's flourishing and expanding breast screening programme
More women than men die of cardiovascular disease (CVD) every year, yet females receive only 33% of angioplasties, stents and bypass surgeries; 28% of implantable defibrillators, and 36% of open heart surgeries.
The Swiss company Novartis recently received the FDA approval for the U.S. market for their new osteoporosis drug “Reclast”, a therapy that is only given once a year via a 15-minute infusion. The new treatment option is especially designed for women who suffer from post-menopausal osteoporosis.
The Netherlands — In-vitro fertilisation (IVF) is an overly aggressive treatment and needlessly exposes childless women to substantial risks of complications and serious discomfort, according to researchers at the University Medical Centre, in Utrecht.
New initiative aims at clarification and education.
We asked Professor Badiale about progress in the understanding of women and heart disease.
Currently, five years of treatment with tamoxifen is considered the 'gold-standard' treatment for postmenopausal women with breast cancer. This drug blocks oestrogen, which can help fuel the growth of tumours in some cases.
Five years of therapy with the drug tamoxifen has become the norm for postmenopausal women with hormone-sensitive breast cancer. However, this has several adverse side effects, and studies have continued to compare the effects of other drug therapies with tamoxifen.