Search for: "gene editing" - 304 articles found

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Article • Interdisciplinary diagnostics

Crossing the radiology-pathology boundary

In diagnostics, there used to be a hard divide between radiology and pathology, where methods were largely considered incompatible with one another. However, to pave the way for next-generation diagnosis, Professor Regina Beets-Tan urged both sides to come out from their trenches and appreciate the synergies the fields have to offer. In her presentation at the European Congress of Radiology (ECR)…

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Surgical Flat Panel C-Arms

Vision RFD Hybrid Edition

HighlightsThe Ziehm Vision RFD Hybrid Edition* is a powerful 30 kW** mobile C-arm that is also available withCMOS imaging technology to successfully perform during highly demanding interventional cardiovascular procedures – flexible and everywhere – at any time. With its zero room preparation, the comprehensive mobile hybrid solution easily takes your OR to the next level. Plug in…

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Article • Men are from Mars, women are from Venus

Sex differences in imaging cardiovascular disease

An interplanetary title for a quite down-to-earth topic: The symposium "Men are from Mars, women are from Venus" at the EACVI congress (European Association of Cardiovascular imaging) launched into the differences between the hearts of men and women. While the speakers could firmly establish that both sexes share the same home world, variations in their cardiac anatomy warrant a more…

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Article • Experts explore impact of technology

AI in radiology: helper or bane of society and the environment?

The climate crisis and AI – arguably two of the most hotly-debated and relevant topics of our time – share an intricate relationship: While computation of complex AI routines commands an immense carbon footprint, it is these algorithms that might be the very key to mitigate the effects of global warming. In a dedicated session at ECR 2023, radiologists explored the societal and environmental…

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Article • Tackling gender inequality

Radiology – still a “man’s world”?

Gender equity is a key factor in achieving excellence in academic medicine. So far, however, this is only partly reflected in reality: In Europe, women represent 54% of physicians and 40% of radiologists. However, female representation in radiology decreases at increasing levels of leadership. A panel of experts assessed the challenges women have to face in radiology and explored strategies to…

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Article • Potential of large language models for nursing and health science education

ChatGPT: the next big thing in cardiology?

Hardly a day passes without new headlines about ChatGPT, the AI-powered large language model, and its potential applications in healthcare. First results have been somewhat sobering after the initial hype, with the AI’s “hallucinations” often replacing scientific truth. Still, Professor Philip Moons is convinced that the chatbot might bring actual benefits to nursing and health science…

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News • Promising application of "gene scissors"

Using CRISPR-Cas9 to treat anaemia

ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia: beta thalassaemia and sickle cell anaemia.

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Article • Progress, limitations, and opportunities

Precision oncology: incredible potential, but not a miracle cure

Unanswered questions are hampering clinicians in their efforts to get the best out of a precision medicine approach for their patients. Speaking at the Genomics and Precision Medicine Expo in London at the end of May, cancer educator Dr Elaine Vickers said the benefits of being matched to an investigational drug remain questionable for most people with advanced cancer.

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Article • RESTORE hospital programme

Facilitate recovery from hip fracture surgery by geriatric patients

Caregivers at the University of Texas Southwestern Medical Center in Dallas, Texas, have developed a programme designed to facilitate recovery by geriatric patients following hip fracture surgery. The Returning Seniors to Orthopedic Excellence (RESTORE) programme is designed to provide stellar comprehensive collaborative co-managed care for older adults with orthopaedic injuries.

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Article • Imaging investigation and diagnosis

Multiparametric ultrasound: the future of the modality

Multiparametric ultrasound will play an increasing role in imaging investigation and diagnosis as more subspecialities reap the benefits from the modality, Professor Paul Sidhu believes. The leading expert predicts that it will be more cost-effective and comfortable for patients and take point-of-care-testing onto a new level by embracing other parameters in the imaging process.

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Article • Infection prevention

Vaccination: why ‘positive consensus’ is crucial

Vaccination projects across the world are at a pivotal post-Covid moment, according to one of the leading experts in the field. Speaking to Healthcare in Europe ahead of the World Innovation Summit for Health (WISH) congress in Qatar – where vaccination will be a central topic – Dr Jerome Kim said there is an urgent need to regain a ‘positive consensus’ around the value of vaccines. He…

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News • Appeal for an update in radiology departments

Ageing imaging equipment is undermining safety and quality of care for patients

The percentage of medical imaging equipment in Europe that is more than ten years old is alarmingly high, and the broad disparities in equipment density between European countries remain. These are the principal findings in the 2021 edition of the COCIR Medical Imaging Equipment Age Profile and Density. This has potentially negative consequences for patients and for the budgets of healthcare…

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News • Additional costs that pay off

For women with dense breasts, MRIs are cost effective for detecting breast cancer

New research indicates that MRIs are cost effective for detecting breast cancer for women with very dense breasts detected by mammography. About 10% of women have extremely dense breasts, and current mammography screening guidelines do not recommend additional imaging tests unless there is a strong family history or genetic risk for breast cancer. Such women face two problems. They have increased…

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News • United appeal

Climate change: 200 health journals call on world leaders to address “catastrophic harm to health”

'Unite behind the science' is an essential appeal from climate activist figurehead Greta Thunberg – and so they did: Over 200 health journals across the world have come together to simultaneously publish an editorial calling on world leaders to take emergency action to limit global temperature increases, halt the destruction of nature, and protect health. While recent targets to reduce…

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Sponsored • Flexibility and freedom of movement

C-arm adds accuracy to cardiovascular interventions

Alongside the worldwide increase in longevity, inevitably with chronic health conditions rising, cardiovascular procedures and OR utilisation have surged. Thus the efficient and safe performance of surgeries is even more important. The intraoperative use of mobile C-arms increases accuracy, improving clinical outcomes, which can significantly reduce revision rates and thus overall healthcare…

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Article • Seeing the advantages

Digital pathology adoption accelerates

Digital pathology (DP) is a game-changer in the workflow, functionality and accessibility of a hospital’s pathology department. As pathologists understand the benefits, and the availability of commercial products and systems increase, alongside data transmission and storage costs decreasing, DP deployment in hospitals is accelerating. Pathology informatics expert Anil V Parwani MD PhD discussed…

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News • Early detection & prevention

Blood-based micro-RNAs indicate colorectal cancer risk

The risk of colorectal cancer can be predicted more accurately by determining seven blood-based micro-RNAs (miRNAs) than by using traditional methods - and can be done so many years before a diagnosis is made. In a current study, researchers from the German Cancer Research Center and the National Center for Tumor Diseases (NCT) Heidelberg show that miRNA profiles provide greater predictive…

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News • Genome editing

Using CRISPR to speed up Covid-19 testing

A research team led by scientists in the labs of Jennifer Doudna, David Savage and Patrick Hsu at the University of California, Berkeley, is aiming to develop a rapid Covid-19 diagnostic test that is much faster and easier to deploy than qRT-PCR. It has now combined two different types of CRISPR enzymes to create an assay that can detect small amounts of viral RNA in less than an hour. Doudna…

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Sponsored • Surgical image and video management

OR becoming an integrated high-performance hub

Operating rooms are extremely complex, and the level of complexity is steadily increasing. This is reflected in the growing number of medical devices, on the one hand, and in the continuously increasing volume of data, on the other. Nowadays, surgical staff are confronted with a flood of highly specialised technology. The challenge is to create workplaces that are as uniform as possible and…

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Article • Heard at SIIM 2021

AI in radiology: unexpected benefits, unintended consequences

Artificial intelligence (AI) could match the impact of PACS on radiology. Covid-19 stimulated the development and testing of AI diagnostic-aiding tools in radiology, an unintended consequence of the pandemic. More image data sets have been created to train AI software – an unexpected benefit for radiology research.

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News • AI in cardiology

Machine learning accurately predicts cardiac arrest risk

A branch of artificial intelligence (AI), called machine learning, can accurately predict the risk of an out of hospital cardiac arrest--when the heart suddenly stops beating--using a combination of timing and weather data, finds research published online in the journal Heart. Machine learning is the study of computer algorithms, and based on the idea that systems can learn from data and identify…

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News • Safe sonography

Medical societies support safety and benefits of ultrasound contrast agents

The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (ASE) have joined the International Contrast Ultrasound Society (ICUS) in recognizing the relatively low risk and important clinical benefits of ultrasound contrast agents (UCAs), which are used routinely around the world to help detect heart disease, stratify the risk of heart attack or stroke,…

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News • Covid-19 prevention side effects

Rare blood clots after Oxford-AstraZeneca vaccine: study sheds more light

A large study from Denmark and Norway published by The BMJ sheds more light on the risk of rare blood clots in adults receiving their first dose of the Oxford-AstraZeneca Covid-19 vaccine. The findings show slightly increased rates of vein blood clots including clots in the veins of the brain, compared with expected rates in the general population. However, the researchers stress that the risk of…

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News • Labs processing 2,000 to 5,000 tests a day

Workflow automation solutions for mid-volume laboratories

Clinical diagnostics company Beckman Coulter announced the European launch of the DxA 5000 Fit, a workflow-automation solution designed to fit into medium-sized labs that run fewer than 5,000 tests a day. The clinical laboratory has gone through trial by fire in 2020, where total testing was 245% of baseline volumes, with ~55% being SARS-CoV-2 molecular tests. Despite vaccines, many industry…

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News • CRISPR-Cas9

An 'on-off switch' for gene editing

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms’ DNA. While the system could potentially be useful in treating a variety of diseases, CRISPR-Cas9 editing involves cutting DNA strands, leading to permanent changes to the cell’s genetic material. Now, in a paper published online in Cell,…

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News • Singlet contrast imaging

Hyperpolarized MRI enables real-time view on metabolic processes

Hyperpolarized MRI is a recent development and its research and application potential has yet to be fully explored. Researchers at Johannes Gutenberg University Mainz (JGU) and the Helmholtz Institute Mainz (HIM) have now unveiled a new technique for observing metabolic processes in the body. Their singlet-contrast MRI method employs easily-produced parahydrogen to track biochemical processes in…

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Article • At ECR 2021

AI experts tackle organ segmentation and health economics

AI is revamping workflows and experts showed how radiologists can integrate it into their department to improve daily practice and healthcare at ECR. The panel also discussed the health economics side of AI to help radiologists define which products make more economic sense for their department. The session tackled automated organ segmentation, an interesting application for AI in radiology.

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News • Virtual booth at ECR 2021

Ziehm Imaging presents clinical packages for cardiovascular intervention

At this year's virtual ECR congress, Ziehm Imaging showcases its portfolio of mobile C-arms and advanced imaging solutions. Highlights on display include two clinical packages for cardio and vascular interventions based on the fully motorized Ziehm Vision RFD Hybrid Edition, that provide clinical users with state-of-the-art imaging support and further workflow integration. The virtual booth,…

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Article • AI tool might reduce surgery

Managing cancer-questionable breast lesions

The management of biopsied breast lesions that are diagnosed as abnormal but are not definitively malignant is challenging and controversial. Treatment ranges from diligent follow-up, with imaging and subsequent biopsy, to surgical excision. Researchers at the Medical University of Vienna (Medizinische Universität Wien), Austria, have developed and validated a software algorithm designed to…

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Article • Gender and medical career

Neurosurgeon, wife and mother of three: breaking social bias against women

Running a neurosurgery department when you’re a woman is rare enough, but if on top of that you’re a mother of three, you’re an exception. You’re also living proof that it is possible to combine a demanding profession with the challenging task of bearing and raising children. A leading Spanish neurosurgeon shared her experience to raise awareness during the recent EANS meeting.

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Article • Healthcare facilities analysed

Cutting Coronavirus air contamination in hospitals

Preventing air contamination in healthcare facilities is crucial to minimise the airborne spread of Covid-19 and its new strains. Universal masking, rigorous use of and safe disposal of PPE, plus building ventilation are vital. Twenty-four studies reporting hospital SARS-CoV-2 air contamination are summarised in a meta-analysis by a multi-institutional team of French researchers. These show that,…

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News • Lessons learned from Covid-19

A 'blueprint' for preventing the next pandemic

Scientific and public health experts have been raising the alarm for decades, imploring public officials to prepare for the inevitability of a viral pandemic. Infectious epidemics seemingly as benign as "the flu" and as deadly as the Ebola virus provided ample warning, yet government officials seemed caught off guard and ill prepared for dealing with Covid-19.

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Article • 'Chaimeleon' project

Removing data bias in cancer images through AI

A new EU-wide repository for health-related imaging data could boost development and marketing of AI tools for better cancer management. The open-source database will collect and harmonise images acquired from 40,000 patients, spanning different countries, modalities and equipment. This approach could eliminate one of the major bottlenecks in the clinical adoption of AI today: Data bias.

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News • Mapping the 'family tree' of cancer

Metastasis monitoring: CRISPR tool catches cancer 'in the act'

When cancer is confined to one spot in the body, doctors can often treat it with surgery or other therapies. Much of the mortality associated with cancer, however, is due to its tendency to metastasize, sending out seeds of itself that may take root throughout the body. The exact moment of metastasis is fleeting, lost in the millions of divisions that take place in a tumor. “These events are…

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News • RNA editing

New mechanism of cancer formation discovered

A team of scientists at the National University of Singapore (NUS) led by Dr Polly Leilei Chen from the Cancer Science Institute of Singapore and Yong Loo Lin School of Medicine has discovered a previously unknown mechanism of cancer formation, the understanding of which may lead to more effective treatment. Their findings concern a process called RNA editing. The DNA code of a gene gets…

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News • High-proof cardiology research

Even a bit of alcohol can increase atrial fibrillation risk

A study of nearly 108,000 people has found that people who regularly drink a modest amount of alcohol are at increased risk of atrial fibrillation, a condition where the heart beats in an abnormal rhythm. The study, published in the European Heart Journal, found that, compared to drinking no alcohol at all, just one alcoholic drink a day was linked to a 16% increased risk of atrial fibrillation…

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News • Cardiac complications

Immunotherapy drugs can lead to higher risk of heart problems

A study of over a thousand cancer patients treated with immunotherapy drugs has found these patients are at greater risk of heart problems, including death from heart attack or stroke. The patients had either lung cancer or malignant melanoma (a type of skin cancer), for which immune checkpoint inhibitors such as a programmed cell death-1 (PD1) inhibitors or cytotoxic T-lymphocyte-associated…

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News • Mobile hybrid imaging, image fusion, endovascular 3D navigation

Ziehm and Therenva present imaging solutions at RSNA 2020

At this year's virtual RSNA congress, Ziehm Imaging showcases its leading portfolio of mobile C-arms and advanced imaging solutions. Highlights on display include the Ziehm Vision RFD Hybrid Edition in combination with Therenva’s EndoNaut solution for advanced endovascular 3D intraoperative navigation as well as the Ziehm Vision RFD 3D, one of the most successful 3D mobile imaging solutions in…

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Article • Detecting coronavirus infections

Covid-19: CRISPR-based test gives GPs quick results

Recent research in Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) has identified two enzymes that can detect Covid-19 RNA as simply as a pregnancy test Jesús Pla, an eminent microbiologist at the Complutense University in Madrid, explained in our exclusive interview. CRISPR technology could help alleviate workloads in packed hospitals and expand testing to primary care and…

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News • 'QCOVID' model

New COVID-19 tool predicts risks of hospital admission and death

A new risk tool, developed by UK researchers to predict a person’s risk of being admitted to hospital and dying from COVID-19 has been published by The BMJ. With cases increasing in the UK and elsewhere, and winter approaching, there is an urgent need for reliable models that predict the likely course of COVID-19, to support decisions about shielding, hospital admission, treatment, and…

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News • For the development of CRISPR/Cas9

Nobel Prize in Chemistry goes to Emmanuelle Charpentier and Jennifer A. Doudna

The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2020 to Emmanuelle Charpentier from the Max Planck Unit for the Science of Pathogens, Berlin, Germany, and Jennifer A. Doudna from the University of California, Berkeley, USA, “for the development of a method for genome editing”, more commonly known as the 'gene scissors' CRISPR/Cas9.

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News • 'Rush to publish'

Have research standards suffered during COVID-19?

The COVID-19 pandemic has created a flood of potentially substandard research amid the rush to publish, with a string of papers retracted or under a cloud and a surge in submissions to pre-print servers where fewer quality checks are made, a leading ethicist has warned in the Journal of Medical Ethics. This has implications for patients, clinicians, and potentially government policy, says…

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Article • Non-pulmonary aspects

The cardiovascular impact of Covid-19

The increased Covid-19 risk to cardiac patients was discussed during an online presentation at ECR 2020. Focusing on the prevalence of pulmonary embolism in Covid-19 patients, Dr Karl-Friedrich Kreitner, Professor of Radiology at the Department of Diagnostic and Interventional Radiology at the Johannes-Gutenberg University in Mainz, Germany, discussed hypotheses which can explain cardiac…

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News • Facial photo analysis

AI uses ‘selfies’ to detect heart disease

Sending a “selfie” to the doctor could be a cheap and simple way of detecting heart disease, according to the authors of a new study. The study is the first to show that it’s possible to use a deep learning computer algorithm to detect coronary artery disease (CAD) by analysing four photographs of a person’s face. Although the algorithm needs to be developed further and tested in larger…

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News • Gender parity

Why heart failure research needs more female authors

While about a quarter of physicians and researchers working in advanced heart failure (HF) and transplant cardiology are women, representation of women leading HF research remains limited, according to new research led by Penn Medicine. The authors say the findings point to a need to support great gender diversity among researchers to drive diversity among clinical trial participants and even…

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Article • Neuroradiology

Alzheimer’s research: A lost century

Lack of understanding around Alzheimer’s disease (AD) has significantly slowed advances in the treatment of this incurable condition. Imaging has proved to be reliable in differentiating between AD and other forms of dementia, and its contribution will continue to help develop profiling, an increasingly interesting approach for the development of new and more efficient drugs, according to Sven…

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News • New tool discovered

Gut microbiome: Crohn’s disease bacteria grown in the lab

Several thousand strains of bacteria live in the human gut. Some of these are associated with disease, while others have beneficial effects on human health. Figuring out the precise role of each of these bacteria can be difficult, because many of them can’t be grown in lab studies using human tissue. This difficulty is especially pronounced for species that cannot live in oxygen-rich…

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Article • The difficulty? Unpredictability in the entire process

Immunotherapy for lung cancer patients

Better outcomes, more favourable prognoses – oncologists and their lung cancer patients didn’t dare to dream about it. Finally, there might be hope. The so-called checkpoint inhibitors (immunotherapy drug) have been used successfully, albeit not for every patient. They are a double-edged sword, with risks as well as opportunities, as explained by Professor Cornelia Schäfer-Prokop.

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News • Sample analysis

Next-generation analytical lab software strengthens data exploration

Scientists in the life sciences can now benefit from upgrades to a suite of analytical software solutions with new features designed to enhance productivity, confidence and accuracy in numerous fields, including proteomics, food safety and biotherapeutic drug development. The latest suite of software strengthens laboratory workflows across a range of applications through expanded capabilities,…

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Article • COVID-19 protection around the world

Coronavirus mask parade: diverse and united

As the coronavirus pandemic continues, face masks become a common sight in our everyday lives. However, there is still lots of room for individuality, as these photos prove. Enjoy!

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News • A novel method

Precise delivery of of therapeutics into the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers.

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News • COVID-19 prevention

Social distancing: does it work?

The number of cases tested positive for COVID-19 initially grew exponentially in China, but then slowed down. Dirk Brockmann, professor at Humboldt-Universität zu Berlin (HU) and project group leader at the Robert Koch-Institut (RKI), and his postdoc Benjamin F. Maier have developed a diffusion model that takes into account the effect of social distancing and other measures to explain this…

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News • Werther effect

Media reports of celebrity suicide linked to increased suicide rates

Media reporting of suicide, especially celebrity suicides, is associated with increases in suicide in the general population, particularly by the same method as used by the celebrity, finds an analysis of the latest evidence published by The BMJ. The researchers say their findings support the continued use and promotion of guidelines on responsible media reporting of suicide, especially when…

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News • Downloadable helper

World’s first artificial pancreas app licensed for type 1 diabetes

The world’s first licensed, downloadable artificial pancreas app for people with type 1 diabetes now launched, based on over a decade of research by Professor Roman Hovorka at the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. The CamAPS FX app works with an insulin pump and a glucose monitor to automatically deliver insulin to people living with the condition…

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News • Radiology congress (update)

ECR 2020 will be online-only due to coronavirus

The 2020 edition of the European Congress of Radiology (ECR) in Vienna, which had been postponed due to safety concerns regarding COVID-19, will not take place on site this year. Instead, the congress organisers at the European Society of Radiology (ESR) opt for an online-only event: "It is with a heavy heart and much regret that the Board of Directors of the European Society of Radiology…

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News • Triple-negative forms impeded

Scientists stop breast cancer cells from spreading in the lab

Biologists have discovered a way to stop cells from one of the most aggressive types of breast cancer spreading in the lab. The study points towards new avenues of research to combat the devastating disease. The results of the study of Triple-Negative Breast Cancer by the team from the Universities of Manchester, Glasgow and Sheffield and funded by Breast Cancer Now are published in Oncogene.…

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News • Outbreak

A genome browser posts the coronavirus genome

Research into the novel Wuhan seafood market pneumonia virus, the deadly "coronavirus" that has forced the Chinese government to quarantine more than 50 million people in the country's dense industrial heartland, will be facilitated by the UC Santa Cruz Genomics Institute. The Genomics Institute's Genome Browser team has posted the complete biomolecular code of the virus for researchers…

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News • Coital research

'Sex in an MRI scanner' – the story behind an extraordinary imaging project

This Christmas marks the 20th anniversary of the publication of “Magnetic resonance imaging of male and female genitals during coitus and female sexual arousal” in The BMJ. In its first year, it picked up the IgNobel prize for medicine, and has since become one of the most downloaded BMJ articles of all time. Dr Tony Delamothe, a former editor at The BMJ, ponders on its success.

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Article • Radiology + data + AI = ?

Today and future radiomics

Radiomics is one of the most exciting topics in radiology. It involves data and artificial intelligence (AI) but very few people know or understand the details. In her lecture ‘How does Radiomics work?’, presented at the German Radiology Congress in Leipzig, Professor Ulrike Attenberger outlined how radiomics will advance radiology but also the obstacles faced along the way.

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News • Advancements in CT and MR

Canon expands the power of AI across imaging modalities

Bringing the power of AI to routine imaging, Advanced intelligent Clear-IQ Engine (AiCE), Canon Medical’s Deep Learning Reconstruction (DLR) technology, is now being integrated across a broader portfolio of scanners with a wider range of clinical applications across modalities. Advanced intelligent Clear-IQ Engine (AiCE) was trained using vast amounts of high-quality image data, and features a…

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News • New research

Cancer patients at higher risk of dying from heart disease and stroke

More than one in ten cancer patients do not die from their cancer but from heart and blood vessel problems instead, according to new research published in the European Heart Journal. For some cancers, like breast, prostate, endometrial, and thyroid cancer, around half will die from cardiovascular disease (CVD). Dr Nicholas Zaorsky, a radiation oncologist, and Dr Kathleen Sturgeon, an assistant…

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Interview • Diagnostics & therapy

AI: Hype, hope and reality

Artificial intelligence (AI) opens up a host of new diagnostic methods and treatments. Almost daily we read about physicians, researchers or companies that are developing an AI system to identify malignant lesions or dangerous cardiac patterns, or that can personalise healthcare. ‘Currently, we are too focused on the topic,’ observes Professor Christian Johner, of the Johner Institute for…

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Article • Artificial intelligence in radiology

Assessing the AI revolution

How will artificial intelligence (AI) affect continuing education and management in radiology? This issue was discussed by an expert panel at the ESR AI Premium meeting in Barcelona. Continuing education – It must be clear what radiologists need to learn about AI; one way to go could be to give it more space in the training curriculum, according to Elmar Kotter, deputy director of the radiology…

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News • CRISPR 2.0

Is 'prime editing' the next step in gene editing?

A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology – CRISPR-Cas9 and a reverse transcriptase – into a single machine. The system, called “prime editing,” is capable of directly editing human cells in a precise, efficient, and highly versatile fashion. The approach…

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News • Bleeding disorder

Hemophilia: a lot more prevalent than thought

More than 1,125,000 men around the world have the inherited bleeding disorder of hemophilia, and 418,000 of those have a severe version of the mostly undiagnosed disease, says a new study led by McMaster researchers. This is three times what was previously known. Only 400,000 people globally were estimated to have the disorder which is caused by a defect in the F8 or F9 gene which encodes…

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News • Gene editing

Taking CRISPR one step further

Researchers at ETH Zurich have refined the famous CRISPR-Cas method. Now, for the very first time, it is possible to modify dozens, if not hundreds, of genes in a cell simultaneously. The biotechnological method CRISPR-Cas offers a relatively quick and easy way to manipulate single genes in cells, meaning they can be precisely deleted, replaced or modified. Furthermore, in recent years,…

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News • Collaboration

Partnership to enhance pharma drug development and single cell research

Olympus and Cytosurge AG, developer of the disruptive and patented FluidFM technology, announced their collaboration to significantly expand the awareness and availability of the FluidFM BOT* – a cutting-edge system for single cell manipulation and live cell imaging – in Europe, the Middle East and Africa (EMEA). By pooling together each other’s world-class competences and by listening to…

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News • Gene-editing

CRISPR baby mutation significantly increases mortality

A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life, according to an analysis by scientists from UC Berkeley. The researchers scanned more than 400,000 genomes and associated health records contained in a British database, UK Biobank, and…

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News • GBO customer magazine

bioLOGICAL: Safety when it matters

The latest issue of Greiner Bio-One's (GBO) customer magazine bioLOGICAL is out now. The third edition of the magazine contains exciting articles about arterial and venous catheter as well as the General Data Protection Regulation in health care section. On a trip to Helsingborg, GBO introduces Vigmed and its products. The Swedish company was taken over by Greiner Bio-One in 2017.

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Sponsored • High-performance tube sorting

Easy access: The new lightweight target bin with permanent display

More than 16 years of experience in the complex matter of workflows within clinical labs leads to the latest generation of ASP SortPro tube sorter. To make the investment in sorting devices efficient, these must be integrated perfectly into the workflow. The ASP team sold hundreds of tube sorters to clinical labs and hospitals worldwide. In all these installations the German engineers have…

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Article • Digital pathology & AI

Unleashing the power of digital pathology for precision medicine

Digital pathology, combined with the power of Artificial Intelligence (AI), is one of the most promising fields for the delivery of precision medicine. In the first keynote address for the 5th Digital Pathology & AI Congress (Europe) held in London last December, Professor of Pathology, Marilyn Bui, focused on how digital pathology is impacting on precision medicine. During her address,…

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News • Tailored treatment needed

Half of patients on statins fail to reach ‘healthy’ cholesterol level after 2 years

Half of patients prescribed statins in primary care fail to reach ‘healthy’ cholesterol levels after two years of treatment with these drugs, reveals research published online in the journal Heart. The findings back up those of previous studies, and highlight the need for personalised medicine to tackle high cholesterol and lower the significantly increased risks of future heart disease and…

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News • Building a risk profile

Audiologists seek genetic link to tinnitus

Tinnitus, more commonly known as ringing in the ears, is a serious audiological and neurological condition affecting nearly 50 million Americans. Noise and music exposure are the predominant environmental risk factors for tinnitus. There is no known cure, and there are no FDA-approved medications developed specifically to treat it. The fact is, tinnitus is very common but not well understood. A…

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News • Gene editing

DNA “shredder”: a different kind of CRISPR

In the last six years, a tool called CRISPR-Cas9 has transformed genetic research, allowing scientists to snip and edit DNA strands at precise locations like a pair of tiny scissors. But sometimes, it takes more than scissors to do the job. Now, a collaborative international team has unveiled a new CRISPR-based tool that acts more like a shredder, able to wipe out long stretches of DNA in human…

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News • Against rebound

Pancreatic cancer: Genome-wide analysis reveals new strategies

For some cancers, initial treatment with chemotherapy brings positive, but only temporary, results: tumors shrink, but then rebound as the cancer becomes drug-resistant. This pattern of remission-resistance-relapse is particularly true for pancreatic cancer, an aggressive disease in which early success is often countered by eventual disease progression. To wit: The one-year relative survival rate…

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Interview • POC ultrasound

Touchscreen and exam pre-set assets

During our interview with Professor Felice Eugenio Agrò, Professor, Director and Chairman of the Postgraduate School in Anaesthesia and Intensive Care at the University Campus Bio-Medico of Rome, he spoke of the use of Mindray’s TE7 ultrasound system, which provides a touchscreen and focused exam pre-sets. ‘Anaesthesiologists are seeking safe and accurate methods during procedures. Many…

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News • Hope for diabetics

Insulin-producing cells grown in lab

UC San Francisco researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes. Replacing these cells, which are lost in patients with T1 diabetes, has long been a dream of regenerative medicine, but until now scientists had not been able to figure out how to produce cells in a…

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News • Precision medicine

Europe looks to cells for a healthier future

How can we detect the first signs of disease as early as possible? Could closer investigation at the cellular level help to quickly prevent disease progression through appropriate treatment? The European Union is now investing a million euros over a one-year period to devise the plan for a fundamentally new approach to understanding the constant changes within cells and their relationships to one…

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Article • Neuroradiology

Dementia – MRI is the first step in diagnosis

Brain imaging in patients with cognitive complaints need to be viewed differently when using MRI to diagnose and treat patients with dementia, says Dr. Christopher Hess, who will discuss the role of MRI in the adjunctive diagnosis of dementia in his talk at the Garmisch Symposium. In addition, general radiologists need to recognize the important findings related to dementia when making a…

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Article • Getting personal(ised)

Pathology: Moving us towards precision medicine

The European Society of Pathology (ESP) holds its European Congress of Pathology (ECP) at different venues annually. This year, in Spain, 3,448 delegates from 87 countries attended. There, ESP president Dina Tiniakos spoke about the increasing role of pathology in precision medicine including challenges linked to digitisation. ‘Precision medicine is the centre-point for cancer management, but…

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Video • Controversial research

HIV and gene editing: beware of the butterfly effect, cautions expert

The claim of a chinese professor has caused quite a controversy: He Jiankui announced that he successfully modified human DNA to prevent two girls from contracting HIV. Upon the leak of this research, ethicists and scientists alike condemned Jiankui's gene editing in humans. West Virginia University Vice President and Executive Dean for Health Sciences Dr. Clay Marsh says that although “a lot…

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Article • Innovations

Aiding radiologists to stride forward

Growth! New hardware, new software, richer imaging, enhanced communication and image transfer plus artificial intelligence (AI) are all pushing the pace that medical organisations, radiologists and device manufacturers must run to keep up. We spoke with Dr Erik Ranschaert, President of EuSOMII, about today’s changing face of radiology.

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Video • Gene editing

The future of CRISPR in plastic and reconstructive surgery

The CRISPR genome editing technique promises to be a "transformative leap" in genetic engineering and therapy, affecting almost every area of medicine. That includes plastic surgery, with potential advances ranging from prevention of craniofacial malformations, to therapeutic skin grafts, to new types of rejection-free transplants, according to a paper in the November issue of Plastic…

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Sponsored • Point-of-care

Improving the safety and quality of pediatric emergency care with POC ultrasound

Point-of-care ultrasound (POCUS) has become an important adjunct to clinical diagnosis and procedural guidance in the Pediatric Emergency Department (PED), supported by literature demonstrating that its use can improve patient safety and expedite life-saving care. POCUS further helps to reduce costs and children’s exposure to ionizing radiation. Not only is POCUS ideally suited for…

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Article • The revolution escalates

AI image analysis: Opportunity or threat?

'Image Computing, including image analysis, artificial intelligence, artificial neural networks und deep learning, is starting a revolution,’ says Dr Paul Suetens, professor of Medical Imaging and Image Processing at University Hospital Leuven. Artificial Intelligence (AI) is not new – research in this field was carried out as far back as the 1950s – but, whilst in the early days AI learnt…

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News • Oncology

Discovering cancer cell mutations with optimized technologies

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results. A team of researchers has developed a new framework that can combine three existing methods of finding these large mutations - or structural…

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News • Diagnostic lab system

DxM MicroScan WalkAway System now available on the market

Beckman Coulter announced commercialization of its DxM MicroScan WalkAway system, a diagnostic solution for bacterial identification and antibiotic susceptibility testing for microbiology laboratories. The DxM MicroScan WalkAway system uses direct minimum inhibitory concentrations (MIC) for detection of antimicrobial resistance, offering greater confidence in results through gold-standard…

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News • Tumor research

Growing brain cancer in a dish

Austrian researchers have accomplished an astounding feat: They created organoids that mimic the onset of brain cancer. This method not only sheds light on the complex biology of human brain tumors but could also pave the way for new medical applications.

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News • Profession in crisis

Burn-out and heavy drinking in surgeons: Is there a way out?

Burn-out, depression, heavy drinking: Surgeon's seem to be in deep trouble, according to an editorial published in the Journal of ISAKOS (JISAKOS). It is high time for the profession to fix this problem itself before the government steps in, urges leading surgeon Professor Niek van Dijk of the Academic Medical Center in Amsterdam, citing various published studies - and offers solutions on how to…

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News • Man against machine

AI is better than dermatologists at diagnosing skin cancer

Researchers have shown for the first time that a form of artificial intelligence or machine learning known as a deep learning convolutional neural network (CNN) is better than experienced dermatologists at detecting skin cancer. In a study published in the leading cancer journal Annals of Oncology, researchers in Germany, the USA and France trained a CNN to identify skin cancer by showing it more…

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Article • Economies of scale

Lab medicine: Network consolidation continues

Laboratory networks are consolidating across the globe as they seek to deliver a more efficient and cost effective service. The latest developments on several continents were outlined at the FiLM 2018 – Frontiers in Laboratory Medicine congress held in Birmingham, UK in January. With consolidation viewed as a way to deliver economies of scale, it was a recurring theme at the congress with…

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Sponsored • World-class technologies

New cutting-edge products and clinical applications

“With Your Stories – lifetime healthcare support” is the ­future-driven approach combining the best of two worlds by using our insight and expertise in medical imaging systems and laboratory instrumentation to benefit patients through even better prevention, diagnosis, treatment and follow-up and thus help them in the pursuit of a healthy life.

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Sponsored • A discipline transforming

Adding value with AI in medical imaging

In the next five to 10 years, artificial intelligence is likely to fundamentally transform diagnostic imaging. This will by no means replace radiologists, but rather help to meet the rising demand for imaging examinations, prevent diagnostic errors, and enable sustained productivity increases.

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News • When proteins go bad

Data detectives uncover new suspect in Alzheimer's

The mass pursuit of a conspicuous suspect in Alzheimer’s disease may have encumbered research success for decades. Now, a new data analysis that has untangled evidence amassed in years of Alzheimer’s studies encourages researchers to refocus their investigations. Heaps of plaque formed from amyloid-beta that accumulate in afflicted brains are what stick out under the microscope in tissue…

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News • Gene editing

CRISPR-based technology DETECTR can detect viral DNA

A powerful genome editing tool can be deployed as an ace DNA detective, able to sniff out DNA snippets that signal viral infections, cancer, or even defective genes. This genetic detective, developed in the laboratory of Howard Hughes Medical Institute (HHMI) Investigator Jennifer Doudna at the University of California, Berkeley, uses the genome-slicing system known as CRISPR. By combining the…

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News • Neurogenesis

These genetic ‘switches’ determine our brain development

UCLA researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains and, in some cases, set the stage for several brain disorders that appear later in life. The human brain differs from that of mice and…

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News • High levels, low levels

How caffeine may help diagnose Parkinson’s disease

Testing the level of caffeine in the blood may provide a simple way to aid the diagnosis of Parkinson’s disease, according to a study published in the online issue of Neurology, the medical journal of the American Academy of Neurology. The study found that people with Parkinson’s disease had significantly lower levels of caffeine in their blood than people without the disease, even if they…

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News • Genome editing

CRISPR treatment may prevent hearing loss

Using molecular scissors wrapped in a greasy delivery package, researchers have disrupted a gene variant that leads to deafness in mice. A single treatment involving injection of a genome editing cocktail prevented progressive hearing loss in young animals that would have otherwise gone deaf, Howard Hughes Medical Institute (HHMI) Investigator David Liu and colleagues report in the journal…

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News • Duchenne

Researchers create skeletal muscle from stem cells

Scientists from the University of California, Los Angeles (UCLA) have developed a new strategy to efficiently isolate, mature and transplant skeletal muscle cells created from human pluripotent stem cells, which can produce all cell types of the body. The findings are a major step towards developing a stem cell replacement therapy for muscle diseases including Duchenne Muscular Dystrophy, which…

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News • New recorder

This ‘black box’ has an eye on surgeons’ robotic surgery skills

You may know that your surgeon is using the latest minimally invasive technology for your surgery, but how do you know if they’ve mastered it? To help answer that question, researchers at Keck Medicine of USC looked to a custom recording tool similar in concept to a flight recorder on an airplane. When attached to a robotic surgery system during radical prostatectomy procedures, the most common…

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Article • Medical Fair Asia 2018

WHERE HEALTHCARE MEETS TECHNOLOGY:

- Future for Health - FTR4H Pavilion presenting cutting-edge solutions driving digital and mobile healthcare. - Community Care Pavilion focusing on medical innovations for the ‘silver generation’ and home care Solutions.

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Article • Gene editing

CRISPR system embeds images in DNA

A research team in the United States has developed a revolutionary technique that has encoded an image and short film in living cells. Scientists at the Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) used CRISPR gene editing to encode the image and film in DNA, using this as a medium to store information and produce a code that relates to the individual…

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News • Cancer research

Esophageal cancer “cell of origin” identified

Columbia University Medical Center (CUMC) researchers have identified cells in the upper digestive tract that can give rise to Barrett’s esophagus, a precursor to esophageal cancer. The discovery of this “cell of origin” promises to accelerate the development of more precise screening tools and therapies for Barrett’s esophagus and esophageal adenocarcinoma, the fastest growing form of…

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News • Predicting cognitive decline

Odor identification problems may be a warning bell for dementia

A long-term study of nearly 3,000 adults, aged 57 to 85, found that those who could not identify at least four out of five common odors were more than twice as likely as those with a normal sense of smell to develop dementia within five years. Although 78 percent of those tested were normal – correctly identifying at least four out of five scents – about 14 percent could name just three out…

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Article • Electrospinning

Renewing the promise of bioabsorbable implants

Electrospun materials bring a spark of hope to a cardiovascular landscape darkened by setbacks for reabsorbable stents. It was famously said that implanting a device in a person to cure a disease is to implant a new disease. Simply put, the human body will continually fight against foreign materials, leading to chronic inflammations or repeated interventions.

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Article • Backlog

Ten percent of radiology scanners should be scrapped

One in ten CT scanners and one in five MRI scanners are technically obsolete. Radiologists are sounding the alarm. In 2008, around 60% of all CT scanners and 55% of all MRI scanners were up to five years old; 31% of all CT scanners and 32% of all MRI scanners were between five and ten years old; 9% of all CT scanners and 16% of all MRI scanners were over ten years old.

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News • Oncotype

Updated breast cancer guidelines reinforce genomic testing

Genomic Health announced that the 15th St. Gallen International Breast Cancer Conference Expert Panel endorsed the use of genomic tests in early-stage breast cancer and recognised the Oncotype DX Breast Recurrence Score test for its prognostic ability as well as its value in guiding treatment decisions on adjuvant chemotherapy for patients with early-stage, endocrine sensitive, invasive breast…

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News • Exhibition

Medical Fair Thailand 2017 sold out

Medical Fair Thailand 2017 will be its largest edition yet, with booth space fully sold out since May, featuring 700 exhibitors from 45 countries including 18 National Pavilions and country groups on a show floor that has expanded by 20% compared to 2015, at the Queen Sirikit National Convention Center. Held biennially, Medical Fair Thailand 2017 confirms its position as Thailand’s most…

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News • CRISPR-Cpf1

Firefly gene illuminates ability to edit human genome

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have improved a state-of-the-art gene-editing technology to advance the system’s ability to target, cut and paste genes within human and animal cells—and broadening the ways the CRISPR-Cpf1 editing system may be used to study and fight human diseases.

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Sponsored • Experts' get-together

Toshiba Medical invites you to their MRI User Meeting 2017

Toshiba Medical proudly announces its 2nd MRI User Meeting in collaboration with Clinica Creu Blanca in Barcelona on 22 & 23 September 2017 (at Camp Nou FC Barcelona, Spain). At this MRI User Meeting, international experts will share their experiences and clinical solutions for successful diagnostic imaging in Women's and Men's Healthcare.

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News • Neuro-oncology

Study provides better understanding of how brain tumors ‘feed’

All cancer tumors have one thing in common – they must feed themselves to grow and spread, a difficult feat since they are usually in a tumor microenvironment with limited nutrients and oxygen. A study at The University of Texas MD Anderson Cancer Center has revealed new details about how an enzyme called acetyl-CoA synthetase 2 (ACSS2) allows brain tumors to grow despite their harsh…

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Article • Patient Safety

Obsolescent Medical Imaging Technology Is Undermining Patient Safety

The age of the installed base of medical imaging equipment is continuing to decline dramatically, placing patients at avoidable risk. To draw attention to this deterioration in equipment and the potentially serious consequences, COCIR is launching a new infographic at the 3rd edition of the EuroSafe Imaging presence at the European Congress of Radiology (ECR).

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News • Drugs

The war on drugs causes massive human rights violations

Financial ties between researchers and companies that make the drugs they are studying are independently associated with positive trial results, suggesting bias in the evidence base, concludes a study published by The BMJ today.

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Article • Transplants

Cell-free DNA offers several advantages

As part of a national, joint research project in cooperation with Chronix Biomedical (San Jose, CA/USA/Göttingen/Germany), Professor Michael Oellerich MD is on new biomarkers in organ transplantation, aiming to develop personalised immunosuppression for patients. This also entails the development of molecular test procedures, among others for the early detection of rejection. The keyword here is…

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Article • Compliance

The free ride is over!

At Europe’s most prestigious medical conferences, as many as half of the doctors attending are only there because of the generous sponsorship by pharmaceutical and medical technology companies. The practice has been going on for decades, to the point that continuing medical education (CME) in Europe is heavily dependent on the largess of these companies. In 2018 it all comes to an end when a…

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News • Plaque

Research suggests new contributor to heart disease

Medical professionals have long known that the buildup of plaque in arteries can cause them to narrow and harden, potentially leading to a whole host of health problems — including heart attack, heart disease and stroke. While high blood pressure and artery stiffness are often associated with plaque buildup, new research from engineers at Washington University in St. Louis shows they are not…

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News • Congratulation

Merck honored by R&D Magazine for innovation

Merck, a leading science and technology company, today announced it has received two prestigious R&D Magazine 100 awards – one for its lab water purification systems, and the other for a technology that allows researchers to investigate scientific questions they previously couldn’t address.

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News • Research

Why do children develop cancer?

As new scientific discoveries deepen our understanding of how cancer develops in children, doctors and other healthcare providers face challenges in better using that knowledge to guide treatment and counsel families and patients. In addition, as more children continue to survive pediatric cancer, that counseling may extend into a patient’s adulthood and old age.

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News • Research

Drug engineered from bananas fights deadly viruses

A banana a day may not keep the doctor away, but a substance originally found in bananas and carefully edited by scientists could someday fight off a wide range of viruses, new research suggests. And the process used to create the virus-fighting form may help scientists develop even more drugs, by harnessing the “sugar code” that our cells use to communicate. That code gets hijacked by…

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Research breakthrough in fight against muscle wasting diseases

It is estimated that half of all cancer patients suffer from a muscle wasting syndrome called cachexia. Cancer cachexia impairs quality of life and response to therapy, which increases morbidity and mortality of cancer patients. Currently, there is no approved treatment for muscle wasting but a new study from the Research Institute of the McGill University Health Centre (RI-MUHC) and University…

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Article • Politics

Antibiotic resistance is a threat to global health

Within 15 years effective antibiotics will run out and, far from being an apocalyptic fantasy, a world in which common infections and minor injuries can kill is a very real possibility for the 21st Century. Geoff Sussman, one of the world’s foremost wound experts has warned that antibiotic resistance is posing the biggest single threat to global health. Report: Mark Nicholls

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News • Molecular Genetics

How a Bacterial Cell Recognizes its Own DNA

It may come as a bit of a surprise to learn that bacteria have an immune system – in their case to fight off invasive viruses called phages. And like any immune system – from single-celled to human – the first challenge of the bacterial immune system is to detect the difference between “foreign” and “self.” This is far from simple, as viruses, bacteria and all other living things…

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Article • Oophorectomy

Leading expert takes stand against prophylactic oophorectomy

“I am very concerned about the impact that Angelina Jolie has on the media,” Walter Rocca, professor of epidemiology and neurology at the Mayo Clinic in Rochester, Minnesota, stated. He wasn’t hinting to Jolie’s acting choices or waifish silhouette, but to the confusion surrounding her decision to remove her ovaries to prevent ovarian cancer. By Mélisande Rouger

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Article • Mutations

Dutch scientists build colon cancer progression model

Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression. This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs.

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Article • OR goes digital

The entrance of PACS-Surgery

Picture Archiving and Communications systems (PACS) are well established for managing radiology images. Could this robust and mature technology now become the backbone for creating the digital operating theatre? Report: John Brosky

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Article • DRUG resistance

Cut prescriptions and choose treatments wisely!

Prescribing antibiotics for a viral infection with fever, a cold and a cough? There is no point! This is the best-known example of over-use in medicine. There are also numerous examples of diagnostic procedures and therapies that are pointless, yet still being doled out in surgeries and hospitals – sometimes even harming a patient. This is set to change, according to the German Society of…

News • Organ Transplantation

First successful organ donation from newborn carried out in UK

The very first successful organ donation from a newborn to be carried out in the UK is reported in the Fetal & Neonatal Edition of Archives of Disease in Childhood. The donor was a girl born at term after an emergency caesarean section in the neonatal unit of Hammersmith Hospital, London. The donation involved the kidneys, which were transplanted into a patient with renal failure, and liver…

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LEAN Management

‘Why should something that works for the automotive industry not also facilitate leaner processes in pathology?’ Walter Depner decided to look at The Institute of Pathology in Bern, Switzerland, where the concept was tested for three years.

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News • Anaesthesiology

Accidental awareness under general anaesthesia

A UK study has highlighted the issue of patients waking up from a general anaesthetic while undergoing surgery. The research, which questioned more than 7,100 consultant anaesthetists, revealed that there was about one episode of accidental awareness in every 15,000 general anaesthetics cases in the three million UK operations in 2011.

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Male and female Doktors

Whether it was a constitution of sorts writ on cavernous rock at the dawn of mankind no one knows. What is clear is that since the inception of the first rudimentary societies the male always expected to rule and the female to follow and obey.

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Diagnosing from a distance

An echocardiography system that conveniently slips into a coat pocket, this kind of miniature device is now commercially available. Portable ultrasound has been around for about a decade, but until recently the machines were about the size of a laptop rather than that of a smart-phone

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Embracing a nano-size silken promise

Artificial vascular trees, the growing of heart tissue, nerve regeneration: The World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) held in Vienna this October offered an impressive display of current developments in tissue reconstruction and regeneration, Michael Krassnitzer reports

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A women's heart too often kills her

The biggest cause of death for most adult women in industrialised nations is coronary heart disease (CHD). Why the disease affects the genders differently is still not fully understood. European Hospital Editor Brigitte Dinkloh asked Professor Rafaelle Bugiardini MD FESC, from the Department of Internal Medicine Department, University of Bologna, whether he could explain the reasons and what…

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CIED patients can have MRI examinations

A new generation of cardiovascular implantable electronic devices (CIEDs) includes the Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronisation Therapy Defibrillator (CRT-Ds) and Cardiac Resynchronisation Therapy Pacemakers (CRT-Ps). Professor W R Bauer at University Hospital Würzburg has been significantly involved in their development, EH Editor Ralf Mateblowski to ask him about…

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Celebrating 20 Years of ESTI

This congress was a celebration, marking 20 years since the founding of ESTI, which began as a small group of founding members and has grown to become thriving society contributing to the education in Europe and encouraging worldwide.

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The 129th Congress of the German Society of Surgery

Meeting with EH editor Brigitte Dinkloh, Congress Secretary Professor Alexis Ulrich MD (left), Assistant Medical Director at the Clinic for General, Visceral and Transplant Surgery at the University of Heidelberg, outlined the scientific programme, discussed some impressive advances in surgical procedures, and explained why the gathering bears the slogan Surgery in Partnership.

Hopkins Scientists Turn on Fountain of Youth in Yeast

Collaborations between Johns Hopkins and National Taiwan University researchers have successfully manipulated the life span of common, single-celled yeast organisms by figuring out how to remove and restore protein functions related to yeast aging.

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The benefits of point-of-care ultrasound

Rapid and accurate acquisition of basic diagnostic information through the innovative concept of point of care ultrasound can have significant benefits for patient outcome, costs, reducing mortality and medical-legal risk scenarios. These benefits of point-of-care (POC) ultrasound will be highlighted during a WFUMB session by Italian critical care physician Professor Luca Neri, founder and past…

Ultrasound and the lung

Lung ultrasound is a technique with widespread uses and advantages in a range of areas from critical care through to less urgent medical areas. Most of all, it is of particular help in the rapid diagnosis of acute respiratory failure. During a session at WFUMB, its benefits and the latest techniques will be outlined by medical intensivist Dr Daniel Lichtenstein -- Lung Ultrasound in Acute…

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Molecular Imaging for Alzheimer’s Disease May Be Available in Hospitals Within One Year

Researchers the world over are advancing positron emission tomography (PET) as an effective method of early detection for Alzheimer’s disease, a currently incurable and deadly neurological disorder. Three studies presented at SNM’s 58th Annual Meeting are providing new insights into the development of Alzheimer’s disease while opening the door to future clinical screening and treatments.

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15th birthday for Lab Automation 2011

Focused exclusively on the rapidly growing field of laboratory automation, Lab Automation 2011will discuss and demonstrate the latest scientific and technological advances in this field. Presented by the Laboratory Automation Section (LAS) of the Society for Laboratory Automation and Screening (SLAS), the event is expected to attract more than 4,000 scientists, academics and business leaders.

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EASD 2010 review

7,000 people from 120 countries met in Stockholm this September to hear international experts discuss the progress, solutions and challenges of one of our greatest healthcare burdens. Prevention, self-monitoring, surgery, guidelines, economic problems, drug-safety, and co-morbidities – these are just a few of the problems associated with the care of about 55 million diabetics in Europe.

Agfa at RSNA 2010

Agfa HealthCare is focused on providing excellent imaging solutions to support clinical confidence and improve delivery of health outcomes. At RSNA 2010, the company will demonstrate its engineered solutions that optimize the radiology workflow all along the imaging chain. By bringing the power of IT to radiology, we deliver tools that promote strong collaboration between healthcare providers and…

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The first Carestream Cardiology PACS in Europe

In the historical city of Gouda, in the Netherlands, the 441-bed Groene Hart Ziekenhuis (Green Heart Medical Centre) employs about 150 doctors and serves a local population of 450,000 people. Last September it became the first hospital in Europe to install the new Carestream Cardiology PACS. Launched in 2009, the PACS provides a single integrated platform for diagnosis, reporting, storage and…

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The ultra-high-field MRI symposium

Early problems of ultra-high field Magnetic Resonance Imaging (MRI) have been overcome by successful development of adequate hardware. In consequence big efforts have been achieved in structural imaging, as well in functional imaging. Basic scientists and physicians who work in ultra-high-field MRI in Europe and the USA, met at the Berlin Ultra-high-field Facility (BUFF), in the Max Dehlbrück…

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Should specialist medical training be more flexible?

Specialist medical training programmes should retain some flexibility to help trainee doctors make the right career choices, according to a study published on bmj.com. Some UK medical graduates choose a specialty as soon as they qualify and others after a few years of postgraduate work. But changes to postgraduate medical training mean that junior doctors will generally have to make choices…

Congress presents transvaginal pancreatic resection

Advanced endoscopes have already transformed certain surgical procedures. Thanks to minimally invasive surgery (MIS), such as NOTES (Natural Orifice Translumental Endoscopic Surgery), even bowel resection can be relatively scar-less. Such procedures are entering gastroenterology, as presented at the 40th Congress of the German Society of Endoscopy this March.

Secret to Healing chronic wounds might lie in tiny pieces of silent RNA

Scientists have determined that chronic wounds might have trouble healing because of the actions of a tiny piece of a molecular structure in cells known as RNA. The Ohio State University researchers discovered in a new animal study that this RNA segment in wounds with limited blood flow lowers the production of a protein that is needed to encourage skin cells to grow and close over the sore.

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Nuance customers present speech recognition results at ECR

Nuance Communications, Inc, provides a comprehensive family of speech-driven clinical documentation and communication solutions that enable healthcare-provider organisations to reduce operating costs, increase reimbursement, and enhance patient care and safety. Two of Nuance's healthcare customers presented the results of their speech recognition implementations at the ECR in Vienna.

US radiologists wake up to risks from high radiation doses

An estimated 70 million CT scans are performed annually in the USA, a threefold increase since 1993. US physicians rely on CT scans and other diagnostic imaging procedures to make accurate and speedy diagnoses and, until recently, they have not questioned the radiation dose exposure the patient receives. However, this attitude is changing, as physicians and other medical professionals realise…

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Siemens showcases advanced ultrasound solutions

At the European Congress of Radiology (ECR) 2010 in Vienna, Siemens Healthcare presented its innovative ultrasound solutions. The highlight this year was the new release of its premium Acuson S2000 ultrasound system featuring significant advancements in ARFI technology (Acoustic Radiation Force Imaging) for the detection and quantification of tissue. Combined with a 3D breast volume scanner…

Insulin regulates itself

In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate. However, a surprising discovery was made by Joslin Diabetes Center researchers in animal models of diabetes: insulin is important in regulating its own production.…

RSNA 2009 showcases Agfa HealthCare's newest features for IMPAX

Agfa HealthCare unveiled the latest version of its IMPAX product portfolio at the 2009 meeting of the Radiological Society of North America (RSNA). The improvements to its IMPAX solutions will further increase a radiologist's ability to read more exams, with fewer mouse clicks. Enhancements include new tools supporting multi-planar labeling for volumetric spine studies, new communications tools,…

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Speeding up vaccine production

During the race to produce vaccines against evolving influenza viruses the slowness of their manufacture has turned producers more sharply towards cell culture technology. Using the traditional process, fertilised chicken eggs must first be inoculated with live flu virus, then the resulting egg-adapted virus must be purified and inactivated to produce trivalent inactivated virus (TIV), during…

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ECR 2009

The vast majority of the radiologist's work is now either made possible, or assisted, by computer technology. However, the full significance of that role is to be explored by leading radiologists and computer experts at the ECR Congress 2009.

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Patient data at risk

A transatlantic survey of more than a thousand healthcare professionals has shown that over a third are unwittingly putting personal information at risk by storing patient records, medical images, contact details, corporate data and other sensitive information on mobile devices such as laptops, BlackBerrys and USB sticks - and not adequately securing them.

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Personalise healthcare!

The Old Dominion University in Virginia and Regensburg University Medical Center in Germany are jointly organizing an international conference to discuss recent advances and strategic needs in personalised healthcare (pHealth) care and to foster collaboration between industry and academia.

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Fear of relationships - it's in the genes

There can be many reasons why a person might have relationship problems, but now Swedish scientists at Medical University Karolinska Institutet found a specific gene variant that is associated with how men bond to their partners. The insights can lead to a better understanding of such problems as autism and social phobia.

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Cancer patients are not informed enough

Two thirds of cancer patients receive little or no information about the survival benefits of having palliative chemotherapy before making a decision about treatment, according to a study published on the British Medical Journal website.

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Finding prostate cancer metastates in lymph nodes early

With the help of an engineered common cold virus spreadings of prostate cancer in the pelvic lymph nodes can be visualised with a PET scanner. It is now possible to treat the cancer in an early stage. But the developers of the virus from UCLA's Jonsson Comprehensive Cancer Center see a chance to even use it as a treatment option.

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Britain: The big bug buster

The UK's MRSA rates have been declining since 2006 — and this year could be 50% lower than in 2004. This increasing control over dangerous pathogens has not been achieved without considerable hospital staff efforts, relentless public and government pressures on them, and in-house malcontent about the out-sourcing of cleaning work. Given the cost of nosocomial infections to patients, the NHS…

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How measles virus spread in its host

Every kindergarten undergoes it several times a year: the German measles. Nobody knew exactly how measles enter the body. But it has been thought they come through the surface of airways and lungs. But that is wrong, as researchers from the Mayo Clinic in Minnesota found recently.

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OSIRIX

Designed by a team of radiologists, the latest release of OsiriX 3.0.1 on the Mac Pro 8-core was demonstrated for the first time at the recent European Congress of Radiology (ECR). OsiriX - a powerful image processing software dedicated to DICOM images (.dcm / DCM extension) produced by imaging equipment (MRI, CT, PET, PET-CT etc.) and confocal microscopy (LSM and BioRAD-PIC format) - a…

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Ultrasound technology may reduce breast biopsies

eSie Touch Elasticity Imaging, a new method in ultrasound, demonstrated by Siemens Medical Solutions in March at the European Congress of Radiology, is an adjunct to regular breast ultrasound examinations, and may provide a clinically relevant differentiation of benign and malignant tissue. Several studies have shown promising results, and suggest the method could reduce the number of unnecessary…

MRI in Europe

What a difference a few days can make. The last week in September kicked off with more dire warnings about the potentially disastrous impact that the Physical Agents (Electromagnetic Fields) Directive 2004/40/EC will have on the use of MRI in clinical practice and medical research across the European Union (EU).

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Molecular imaging

In recent years molecular imaging has developed into a hot topic field in medical research, which raised high expectations.

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Med-e-Tel

Med-e-Tel - the International Exhibition and Conference for eHealth, Telemedicine and Health ICT - will present a multitude of ICT healthcare applications for debate.

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The RSNA 2005

Late in November and into early December, as icy air streamed over the shores of Lake Michigan - affirming the nickname `windy city´ for Chicago - radiologists continued to immigrate here en masse for their biggest annual gathering. This year the Radiological Society of North America (RSNA) held its 91st annual meeting, parallel with the scientific congress and trade fair. The exhibition alone…

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Digital operating theatres

World renowned for audio, video, communications and information technology products used for entertainment as well as business communications, Sony has continued to utilise and develop that technological expertise to take an increasing role in operating theatres.

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Disaster!

In August last year, Hurricane Katrina smashed into the USA's Gulf Coast. Within 36 hours a swathe of Louisiana had become a disaster zone.

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Radiology's leading lady

At this year's ECR in Vienna, Helen Carty, the incoming ECR 2004 president, said she felt both honoured - and rather awed - at being entrusted to lead a congress built on friendship, in which 'disparate nations of many creeds and races, rich and poor, come together to give and to share knowledge, experience and science in this nonconfrontational atmosphere'. Awe is something many radiologists…

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