From cancer to AI, from management to new medication: this year's Labmed Forum at MEDICA 2023 in Düsseldorf (November 13-16) once again features an exciting scientific programme.
A new advanced form of CT imaging offers better cardiovascular imaging quality compared to dual-source CT (DSCT) in infants with suspected cardiac heart defects, according to a new study.
Researchers have developed adeno-associated virus variants that target heart muscle cells and can thus be used for the precise treatment of heart diseases.
Self-organizing heart organoids – developed at the Austrian Academy of Sciences – are also effective injury- and in vitro congenital disease models. These “cardioids” may revolutionize research into cardiovascular disorders and malformations of the heart. The results are published in the journal Cell.
A new research project will embrace the combination of 5G telecommunications technology and AI to offer continuous remote monitoring to seriously ill heart failure patients, for example those with Left Ventricular Assist Devices (LVADs).
A new photonics device currently in development aims to reduce unnecessary disabilities by improving the instant, real-time monitoring of newborn babies with harmless light particles.
With the first-in-man implantation of the Berlin Heart Venous Cannula at the LMU University Hospital Munich, Germany, Berlin Heart offers patients with a failing Fontan circulation a unique chance to survive the waiting time for a donor heart. These patients are in a life-threatening condition: their health has deteriorated so much that they desperately need a new heart, but because of their poor…
Michigan State University researchers have created for the first time a miniature human heart model in the laboratory, complete with all primary heart cell types and a functioning structure of chambers and vascular tissue.
Patients with the rare Loeys-Dietz syndrome suffer from aortic enlargement which may result in sudden over-expansion and a fatal aortic tear. In order to prevent this from happening, an aortic prosthesis must be implanted. A team of vascular surgeons at the University Hospital of Zurich was one of the first in the world to risk undertaking this life-saving operation on a child as an emergency…
The 3D functions of the TOMTEC software package helped to establish reference values for volume ultrasound diagnosis of congenital heart defects in children.
While the question is still debated as to whether MRI is the better CT, along comes a potential game changer – a new data based 3-D reconstruction method of heart anatomy and function that aims to replace diagnostic coronary angiography. In the near future not only adult patients with coronary heart disease could benefit from this new technique but also children with complex congenital heart…
Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I study is part of a multi-center collaboration dedicated to employing innovative therapies to improve outcomes for children…
Heart surgery significantly decreases in-hospital mortality among infants with either of two genetic disorders that cause severe physical and intellectual disabilities, according to a new study by a researcher at the Stanford University School of Medicine and his colleagues at the University of Arkansas for Medical Sciences. Trisomy 13 and 18, which result from having extra chromosomes, often…
Duke researchers now have evidence to suggest the fever itself, not its root source, could interfere with the development of the heart and jaw during the first three to eight weeks of pregnancy. Researchers have known for decades that fevers in the first trimester of pregnancy increase risk for some heart defects and facial deformities such as cleft lip or palate. Exactly how this happens is…
Early research results suggest scientists might be on to a way to preserve heart function after heart attacks or for people with inherited heart defects called congenital cardiomyopathies. Researchers at the Cincinnati Children’s Heart Institute report in Nature Communications that after simulating heart injury in laboratory mouse models, they stopped or slowed cardiac fibrosis, organ…
Study shows a simplified examination can be performed routinely on low-risk populations during the first trimester of pregnancy.
Acknowledging the need for faster ultrasound automation, Dr Alexander Weichert explained how automated procedures can assist in the early detection of cardiovascular disease and prenatal diagnostic testing, and why a detailed prenatal diagnosis can reduce mortality and morbidity.
Today, many congenital heart defects can be diagnosed in the unborn child – and even treated in utero. Monique Haak (46), gynaecologist-perinatologist and fetal surgeon at Leids University Medical Center (LUMC) in Leiden, The Netherlands, is an expert in the diagnosis and surgery of fetal heart defects.
In a groundbreaking new study led by University of Minnesota biomedical engineers, artificial blood vessels bioengineered in the lab and implanted in young lambs are capable of growth within the recipient. If confirmed in humans, these new vessel grafts would prevent the need for repeated surgeries in some children with congenital heart defects.
The CSI Congress (Congenital, Structural and Valvular Interventions) is one of the major fixtures for catheter therapy of congenital and structural heart defects. Key moments in this high profile event are live broadcasts and the audience can not only to listen to but also interact with the teams in the cath labs involved.
'In paediatric cardiology, echocardiography is the method of choice for preoperative diagnostic purposes,' explains Professor Dr Emanuela Valsangiacomo-Büchel, senior cardiologist and director of cardiovascular imaging at the University Children’s Hospital Zurich, Switzerland. Report: Axel Viola
Congenital heart defects are the most common congenital disorders found in newborns – around one in a hundred babies are affected. This type of heart defect can be reliably diagnosed with ultrasound, usually during the detailed foetal scan carried out halfway through the pregnancy. Report: Brigitte Dinkloh
ECMO's role in a world's first cardiac procedure: Cardiac specialists in the UK have performed a world’s first operation on a 14-year-old boy suffering a severe heart condition. Mark Nicholls reports.
A hospital with a reputation for trailblazing heart surgery has taken transcatheter aortic valve implantation (TAVI) onto the next step in the UK.
The potential of cardiac magnetic resonance imaging (CMRI) is still largely untapped. One novel application might be ablation follow-up. The first MRI-guided cardiac interventions were performed at Herzzentrum Leipzig, but, as far as coronary imaging is concerned, MDCT remains superior to MRI
Computed tomography (CT) is the modality of choice for many diagnostic issues. Whilst currently its major strength is the visualisation of anatomical detail, future technological improvements may also reduce radiation exposure.
Will MRI become routine modality? Today, thoracic MRI is rarely performed in Europe. But this will change over the next decade, predicts Professor Hans-Ulrich Kauczor, Medical Director of the Radiology Clinic at University Hospital Heidelberg. He expects Germany to be at the forefront of this development because MRI technology, despite the high costs, is already widely used here and because CT…
The German Paediatric Heart Centre (DKHZ) is one of the largest of its kind in Europe. Over 25 years the centre has treated big and small patients with congenital heart defects, very now and then being faced with rare, individual cases that present very particular challenges. In any one year, consultant paediatric cardiologist Professor Martin Schneider MD encounters perhaps five such non-…
New research carried out in the UK has revealed that young children with congenital heart disease are at risk of having harmful toxins in their blood, particularly following surgery. Mark Nicholls reports
Prenatal ultrasound images are the first images we see of new humans. But the prenatal ultrasound first carried out by Professor Ian Donald in the late 50s has little to do with today’s potential with 3-D and 4-D imaging with Doppler and colour Doppler. The three tightly linked disciplines gynaecology, prenatal medicine and obstetrics would now be inconceivable without ultrasound
Adults with congenital heart failure (CHD) are a growing special subset of patients with specific needs; most need lifelong care, but in adulthood many fail to receive it. By Holger Zorn
A cardiologist at a UK hospital has become the first in the world to develop a technique to ‘slice’ 3-D images of the heart into intricate sections using computer software. The method, devised by consultant congenital cardiologist Dr Joseph Vettukattil at Southampton General Hospital, is known as multiplane review (MPR) 3-D echocardiography. This allows cardiologists to identify heart defects…
Royal Philips Electronics is to lead `euHeart´, the new European Union (EU) funded research project that aims to improve CVD diagnosis, therapy planning and treatment.
Ten-year-old Tobias smiles brightly at the photographer. And so do the two physicians next to him. They have good reason to be proud as they were the first surgeons worldwide to treat a very serious congenital heart defect in a child by guiding a catheter with the help of a magnetic navigation system into small lung vessels.
The Department for Paediatric Cardiology at the University Medical Centre, at Johannes Gutenberg University, in Mainz, has extended its range of services for lower impact treatment According to the birth register in Mainz, an annual 1.26% of newborns are diagnosed with congenital heart defects, making these the most common malformation.
A research carried out at six hospitals in the West Midlands, UK, is evaluating the use of pulse oximetry as a screening tool for congenital heart disease in newborn babies. Approximately three percent of infant deaths are caused by these significant heart defects and at the moment only less than half of the affected babies are identified by clinical examination, the current screening technique.
A presentation for the 31st tri-national DEGUM, ÖGUM, and SGUM conference in Leipzig, Germany, by Axel Feldkamp MD (below), Chairman of the DEGUM paediatrics division, and Director of the paediatrics department at Duisburg Hospital.
Since the 1950s, the American Heart Association (AHA) has urged a large number of people to take antibiotics before dental work or other procedures that could flood the bloodstream with bacteria. This antibiotic intake was thought to prevent infective endocarditis.
What is an “open foramen ovale”? The open foramen ovale medical abbreviation PFO for “patent foramen ovale”) is a usually small, only a few millimeter thick, membrane-covered slit in the septum between the atria of the heart. It is a remnant from human embryonic development that usually closes during the newborn period; however, in 10-25% of newborns a small opening remains that generally…
In the last 25 years, fetal echocardiography has become established as an integral component of prenatal medicine. Structural heart defects are found in approx. 0.8% of all foetuses. They are consequently comparatively frequent and head the list of isolated fetal organ malformations. Routine screening of the four-chamber view and the outflow tract allows the experienced investigator to detect…
Children are not small adults. As well as special technical requirements, their treatment needs particular handling by the radiology team.
New ultrasound technologies detect foetal heart defects earlier.
Germany - 0.7% of newborn babies need surgery for congenital heart defects (CHD) - i.e. around 5,000-6,000 children in every 700,000 born.
Cardiac assist devices (CAD) are blood pumps that support the circulatory functions of severely ill cardiac patients.
Fifty years ago Henry Gibbon introduced a vital tool for cardiac surgery - the heart-lung machine. While pioneering efforts were made in the first half of the 20th century, this equipment enabled reproducible operations for either congenital or acquired heart disease in many patients.