Search for: "biofilm" - 58 articles found

News • Diagnostics

Fast candida detection through sugar pattern analysis

Scientists created precise replicas of Candida sugar coats to understand immune responses, enabling fast bedside testing that could replace slow lab cultures.

News • Bacterial buildup to myocardial infarction

Heart attacks may be triggered by infection, study finds

An unexpected trigger for heart attack: Researchers show that dormant bacteria can contribute to atherosclerotic plaques and fatal myocardial infarction, effectively making it an infectious disease.

Extensive testing demonstrates the efficiency of the Pentax Medical PlasmaTyphoon™+

Patient safety is at the heart of every medical advancement, and technologies like endoscopes have been pivotal in transforming surgery by enabling minimally invasive procedures. This evolution has led to safer operations, reduced complications, and improved patient outcomes. However, these advancements depend on rigorous hygiene protocols for reusable medical equipment.

News • Hidden habitat for Listeria, E. coli and more

Microplastics help pathogens survive wastewater treatment

Wastewater treatment fails to kill several human pathogens, such as Listeria or E. coli, when they hide out on microplastics in the water, according to a new study.

News • Flexible device reduces biofilms

Bioelectronic patch 'electrifies' bacteria to prevent infections

Rsearchers developed a novel bioelectronic device that taps into the natural electrical activity of certain bacteria found on our skin, paving the way for a drug-free approach to managing infections.

News • Persistence of K. pneumoniae and E. coli

Exploring long-time colonization with resistant enterobacteria

Once a patient’s body has been colonized by resistant bacteria, they can persist for a long time, a new study by the University and University Hospital of Basel shows.

News • Potency against multidrug-resistant bacteria

Synthetic antibiotic shows promise against serious chronic infections

A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against ‘superbugs’ such as MRSA, a new study shows.

News • Health monitoring technology

Relieving healthcare system burden with wireless biosensors

Smart catheters, smart diapers or wound dressings: a new approach to wireless biosensors from Malmö University opens up options for more patient-controlled ways of infection detection.

News • Strain mapping and antimicrobial properties

Smart coatings give early warning for implant failure

Newly developed “smart” coatings for surgical orthopedic implants can monitor strain on the devices to provide early warning of implant failures while killing infection-causing bacteria.

Hip arthroplasty for femoral neck fractures – but without the complications

Arthroplasty for femoral neck fractures has seen enormous progress in recent years, but complications due to infections are still a major problem. With good preparation and the right technique, however, orthopaedic surgeons can take away much of the horror of this scenario.

News • Green revolution

Bacteria could power medical sensors

Engineers have developed a biofilm capable of producing long-term, continuous electricity from an individuals' sweat.

News • CD4-PP vs. UTI

Reducing the risk of infection for patients with urinary catheters

Indwelling catheters through the urethra often cause bacterial infections. A newly discovered synthetic peptide is a promising treatment option, even against antibiotic-resistant pathogens.

News • Surface treatment

Preventing deadly hospital infections without antibiotics

Hospital-acquired infections are dangerous for patients and costly for clinics. A novel surface treatment could help improve the safety of medical devices and ease the economic burden.

Periprosthetic joint infection: a complex issue

Periprosthetic joint infection (PJI) can be an enormous challenge for orthopaedists and trauma surgeons. Antibiotic-loaded bone cement is an important element in a prevention strategy.

A breakthrough technology for endoscope drying and storage

Due to their complex design, reusable endoscopes have been long recognized to require thorough reprocessing to properly disinfect. In practice, the drying of the endoscope is often underestimated.

News • Microbiology

Using 3D printing technique to create biofilms

Researchers at the University of Rochester, and Delft University of Technology in the Netherlands recently developed a 3D printing technique to engineer and study biofilms—three-dimensional communities of microorganisms, such as bacteria, that adhere to surfaces. The research provides important information for creating synthetic materials and in developing drugs to fight the negative effects of…

News • Repurposing bacteria

‘Living medicine’ could treat drug-resistant infections

Researchers at the Centre for Genomic Regulation (CRG) and Pulmobiotics S.L have created the first ‘living medicine’ to treat antibiotic-resistant bacteria growing on the surfaces of medical implants. The researchers created the treatment by removing a common bacteria’s ability to cause disease and repurposing it to attack harmful microbes instead.

News • A new tool to combat superbugs

Defeating antibiotic resistant bacteria with 'molecular tweezers'

Antibiotic resistant bacteria are a looming super threat – heralding a time when our drugs will no longer be effective against prevalent infections. Hospitals are already coping with treatment-resistant bacterial infections. Cognizant of the threat and thinking outside the box, BGU scientists and German and American colleagues have developed a pair of 'molecular tweezers' to destroy the biofilm…

News • Protection from bacteria, fungi, viruses

Antimicrobial technologies – how do they work?

Antimicrobial technologies such as coatings and textiles containing silver and copper are helping people during the Covid-19 pandemic by ensuring that whatever they touch, whether that is a door handle or their own mask, is free from live SARS-CoV-2 particles. But how exactly do these antimicrobial technologies work? How can a silver, copper or even polymeric coating kill microorganisms such as…

News • Biochemistry

Potential trigger of Crohn’s disease found

Potentially game-changing research led by McMaster University scientists may finally bring relief to millions of people worldwide living with Crohn’s disease. Investigator Brian Coombes said his team identified a strain of adherent-invasive E-coli (AIEC) that is strongly implicated in the condition and is often found in the intestines of people with Crohn’s disease. “If you examine the gut…

News • Putting pathogens on mute

A novel strategy for treating hospital germs

Researchers have developed an innovative method to disrupt the formation of biofilms and thus facilitate the treatment of infections with Pseudomonas aeruginosa.

Article • Preventing endoscope contamination

Ways to enhance hygiene in endoscopy

Stringent endoscope cleaning between procedures is vital. However, with so many steps in the process – plus high demand for rapid turnaround of endoscopes – contamination and biofilm build-up are still being reported. Endoscope hygiene and cleaning protocols were central to an online event organised by Pentax Medical, with important contributions from leading specialists. The event examined…

News • Hospital germs

The reasons for different adhesion mechanisms of bacteria

Researchers have shown why hospital germs adhere strongly to surfaces from which water simply rolls off, but bind so poorly to surfaces that are easily wetted by water.

News • Peptide synthesis

Making drug-resistant bacteria sensitive to antibiotics again

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

News • 'Ancientbiotics'

Medieval medicine against antibiotic resistance

Antibiotic resistance is an increasing battle for scientists to overcome, as more antimicrobials are urgently needed to treat biofilm-associated infections. However, scientists from the School of Life Sciences at the University of Warwick say research into natural antimicrobials could provide candidates to fill the antibiotic discovery gap.

Challenges of periprosthetic infection

Periprosthetic joint infection (PJI) is on the increase internationally. In Germany, for example, around 14,500 cases of PJI in hip and knee replacements occur annually. 5,100 of those are caused by multidrug resistant pathogens. ‘Eighty-seven percent of those affected die within five years,’ orthopaedic surgeon Professor Rudolf Ascherl MD pointed out during the Heraeus Symposium held at the…

Article • Significant improvement in cleaning, disinfection and sterilisation

Surgical robots must also be hygienic

Modern healthcare without hand hygiene? Inconceivable – particularly in the operating room (OR). But what happens when it is not the surgeon who handles the scalpel, but a robot? Robotic surgery, just like surgery performed by humans, always carries a risk of microbial transmission to the patient, says Professor Johannes K-M Knobloch of University Hospital Hamburg-Eppendorf (UKE). A specialist…

News • Sweet infection control

Manuka honey ‘sandwich’ could be the key to fighting infections

Layering minute amounts of Manuka honey between layers of surgical mesh acts as a natural antibiotic that could prevent infection following an operation, new research has shown. Meshes are used to help promote soft tissue healing inside the body following surgery and are common in operations such as hernia repair. However, they carry with them an increased risk of infection as the bacteria are…

Drying in endoscope reprocessing: Essential to patient safety

In practice, the drying of the endoscope is often underestimated and therefore a possible pitfall for hygiene and reprocessing steps. As the importance of endoscopic retrograde cholangio-pancreatography (ERCP) procedures and their impact on patients’ lives remains unwavering, the medical community is continuously looking for ways to improve this field of expertise. What better way to learn more…

Article • Infection control

Local antibiotics improve results

Hip and knee joint surgeries are among the most common procedures in orthopaedics and trauma surgery and complications can occur. Rare, but serious, among these is periprosthetic joint infection (PJI), which causes high costs in healthcare and stress for patients. PJI is caused by microorganisms that form a biofilm on the surface of the implant and, in this sessile state, they are difficult to…

Article • Infection - defect - regeneration

Challenges in septic bone surgery

Infections associated with osteosynthesis and prostheses are not to be underestimated: the infection rate is reported to be one to three percent after joint prosthetic surgery and five to 10 percent after osteosyntheses. ‘When you include later infections, the rate is twice as high,’ says Professor Andrej Trampuz, infectologist and Head of the Centre for Septic Surgery at the Centre of…

News • Pseudomonas aeruginosa

Developing a new active ingredient against chronic infections

Chronic lung infections caused by the bacterium Pseudomonas aeruginosa require complex and, in most cases, long-term treatment with antibiotics—new medication is badly needed.

Article • Multi-drug resistance

Aiming for anti-biofilm strategies

The association of biofilms with multi-drug resistance has highlighted the need for further understanding of biofilms and for anti-biofilm strategies.

News • Antibiotic-loaded bone cement

Reduction of infection risk in femoral head fractures by 66%

Good news for World Antibiotics Day on November 18th. As local substances carriers, antibiotic-loaded bone cements from Heraeus help in the battle against implant-associated infections in orthopaedics and trauma surgery to prevent infection. This is demonstrated by a new randomised study from Great Britain in which the use of double-loaded antibiotic bone cement following femoral head fracture…

News • Molecular troublemakers

How proteins prevent communication between bacteria

They may be slimy, but they are a perfect environment for microorganisms: biofilms. Protected against external influences, here bacteria can grow undisturbed, and trigger diseases. Scientists at Kiel University, in cooperation with colleagues at the Hamburg University of Technology (TUHH) in Hamburg-Harburg, are researching how it can be possible to prevent the formation of biofilms from the…

Article • Wound infection

The importance of suture material

Wound infections after surgery are not uncommon and can be fatal. In Germany, postoperative wound infections are now the most common type of hospital acquired infection (HAI), with a proportion of 24%.

News • Alternative therapy

Potent nanodrug combast antibiotic-resistant infections

A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections.

News • bacterial enzyme

Possible approach to tackle infections from hospital germs

Microbiologists at the Universities of Münster and Nottingham, in England, have analysed an enzyme which might play an important role in the treatment of infections from the hospital germ pseudomonas aeruginosa. They have decoded the three-dimensional structure of the enzyme and revealed its function.

Nanotech weapon against chronic bacterial infections in hospitals

Australian researchers develop a new technique that tricks bacterial biofilms into dislodging from their protective matrix, making them vulnerable to treatment with antibiotics.

News • Microorganisms

Guidelines aimed at preventing build-up of dangerous biofilms

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms, which contribute to antimicrobial resistance.

Article • Infection Control

Periprosthetic infections: a new disease

Early diagnosis and effective therapy of periprosthetic joint infections (PJI) remain a challenge for many physicians due to the complexity and heterogeneity of clinical symptoms. As individual solutions are needed, opportunities to discuss and exchange ideas are welcome, as clearly shown during the satellite symposium on the diagnosis and treatment of periprosthetic knee infections held at this…

Article • Contamination management

Implant and tissue infections

Prosthetic joint infections (PJI) are the most frequent complication in orthopaedic implant patients and may occur any time: weeks, months, or even years after an implantation. Report: Ludger Weß

Curetis Joins European Prosthetic Joint Infection Cohort Study

Curetis AG, a developer of next-level molecular diagnostic solutions, today announced it has joined the European Prosthetic Joint Infection Cohort Study (EPJIC).

Smart molecular diagnostic tools are on target

Personalised medicine is often equated with the development of drugs tailored to the genetic make-up of patients or cancers.

Transplants under silent attack

The number of patients treated with implants – from cardiac pacemakers, heart valves and vascular implants to artificial hips and knees – is rising worldwide.

Molecular diagnostics platform

Curetis and Heraeus Medical collaborate

Curetis AG and Heraeus Medical GmbH have signed a collaboration agreement to jointly develop a novel Unyvero™ cartridge for the detection of pathogens and antibiotic resistances in implant & tissue infections (ITI).

Deadly 2011 E. coli Strain Decoded

The secret to the deadly 2011 E. coli outbreak in Germany has been decoded, thanks to research conducted at Michigan State University.

Better safe than sorry

Five recommendations to prevent central venous catheter-related infections. Catheter-related bloodstream infections are the third frequent infection in the intensive care unit (ICU) after pneumonia and peritonitis worldwide. The incidence of CVC infections lies between 1-4 for 1,000 catheterdays. This means for the USA, as an example, that more than five million patients annually need a central…

Concerted efforts to combat prosthetic joint infections

Bacteria are highly flexible when it comes to choosing a vehicle to enter a human body. During orthopaedic surgery, they may well settle on a prosthetic joint and cause immediate or delayed infections.

Plasma therapy: an alternative to antibiotics?

Cold plasma jets could be a safe, effective alternative to antibiotics to treat multi-drug resistant infections, says a study published this week in the January issue of the Journal of Medical Microbiology. The team of Russian and German researchers showed that a ten-minute treatment with low-temperature plasma was not only able to kill drug-resistant bacteria causing wound infections in rats but…

Further increase in number of exhibitors

The COMPAMED, the leading specialist international trade fair for suppliers to the medical manufacturing market, is held parallel to the MEDICA, the world's largest medical trade fair, each year and showcases the dynamism and innovative power of the medical technology sector. The COMPAMED 2008, High tech solutions for medical technology, will, with around 500 exhibitors from 30 nations, once…

A reprocessor for ENT endoscopes

In bronchoscopy and gastroenterology, reprocessors are commonly used to provide a quick availability of endoscopes. However, ENT departments do not dispose of dedicated material, according to the French company Soluscope Group, which manufactures endoscope reprocessors and the detergents used to wash and disinfect them.

At a glance

Where are the most high-tech start-ups? That`s an easy one: Silicon Valley. But who comes in a close second? Surprisingly: Israel. Further: Israel ranks Number 1 in terms of availability of scientists and engineers and Number 2 in quality of higher education. The result of this impressive track record is a wide range of successful enterprises and products, particularly related to the life…

New insights, algorithms and debates

For the first time in 33 years, wound healing was the focus of a dedicated session at the 33rd annual VEITHsymposium for vascular surgeons in New York (11/06). This underscores the fact that wound healing is heading increasingly towards a speciality that warrants the special attention of dedicated people willing to embrace an interdisciplinary approach to non-healing or complex wounds.