News • Bioelectric patterns
Scientists listen in on the ‘electrical language’ of breast cancer
New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread.
Cancer
Article • Tissue-engineered glioblastoma model
3D brain tumour in a dish to personalize cancer treatment
It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.
Article • Early detection approach
Multi-cancer blood tests could shake up screening
New tests can identify over 50 types of cancer and boost detection of traditionally elusive cancers from tumour DNA in blood, researchers showed at the ESMO congress in September. These multi-cancer early detection (MCED) tests in development can spot common cancer signals and predict where the signal comes from in the body, results from a prospective investigation suggest.
Article • Visceral imaging
Endosonography: AI takes on the “supreme discipline”
Endosonography poses unique challenges for medical professionals, because two demanding disciplines have to be mastered at the same time. The use of artificial intelligence (AI) could help speed up the notoriously slow learning curve of the procedure, says Prof Dr Christoph F. Dietrich. At the Visceral Medicine Congress in Hamburg, the expert explained how AI can help endosonography achieve…
News • Metastatic recurrence
Researchers discover mechanism responsible for colon cancer relapse
Researchers in Barcelona discovered the population of residual tumour cells responsible for the recurrence of colorectal cancer in other organs after removal of the primary tumour.
News • Stereotactic body radiotherapy
Advanced radiotherapy speeds up prostate cancer treatment
An advanced radiotherapy technique can be used to safely treat prostate cancer patients in as little as one to two weeks, compared with the current standard, which takes one to two months.
News • Tumor location as important growth factor
New molecular microscopy uncovers breast cancer spread
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease.
News • Nasopharyngeal cancer study
Covid vaccination improves effectiveness of cancer treatment
Until now, it was feared that vaccination against Covid-19 could reduce the success of treatment for patients with nasopharyngeal cancer. A recent study now gives the all-clear in this regard.
News • Equivalent outcomes in 5 vs 8-week treatment
High-risk prostate cancer: Study confirms effectiveness of shortened radiation therapy
A new randomized study confirms that men with high-risk prostate cancer can be treated with a moderately shortened course (5 vs. 8 weeks) of radiation therapy.
News • Immune systems timulation
Using senescent cells as anti-cancer vaccines
Researchers from Barcelona report that vaccination with senescent cells shows promise in experimental models of melanoma and pancreatic cancer.
News • Bioprinting in cancer
3D printing patient-specific tumours
Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models.
News • Possible biological explanation found
Why are dense breasts associated with increased cancer risk?
The risk of developing breast cancer is higher in breasts with high density. But why is that? Researchers at Linköping University have shown major biological differences that promote cancer growth.
Article • Renal carcinoma differentiation
SPECT/CT improves diagnosis of indeterminate kidney tumours
99mTc-Sestamibi SPECT/CT can aid in the diagnosis of solid renal lesions, especially in cases where contrast enhanced CT findings are inconclusive, according to researchers from the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis, Missouri.
Video • Digital patient support tool
Ovarian cancer: "Olivia" to provide information and support
Patients affected by ovarian cancer can turn to "Olivia": The interactive digital resource provides information about diagnostics, treatment and life with ovarian cancer.
News • Focal therapy study
New prostate cancer treatment to reduce risk of impotence
Focal treatment of prostate cancer involves treating only the tumor and not the entire gland, sparing surrounding tissue and nerves. The method is being evaluated in a research study.
News • New treatment approach
Colon cancer: Overcoming chemotherapy resistance
Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.
News • Leukemia research
How 'chameleon cancers' change their colors to survive treatment
Some leukemias evade treatment by changing their appearance and identity through changing the read-out of their DNA, a new study has found.
News • Filopodia research
'Sticky fingers' in cells keep breast cancer contained
Researchers in Finland have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumours.
News • CSCC study finds distinct subgroups
Cervical cancer: major new clue to understanding aggressiveness
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
News • Children’s cancer
Rhabdomyosarcoma: Blood tests could offer smarter treatment
A simple 'liquid biopsy' blood test could help guide the treatment of children with the cancer rhabdomyosarcoma, a new study reports.
Article • Diagnostic assistant systems
AI in endoscopy: helper, trainer – influencer?
Artificial intelligence (AI) is increasing its foothold in endoscopy. Although the algorithms often detect pathologies faster than humans, their use also generates new problems. PD Dr Alexander Hann from the University Hospital Würzburg points out that the use of AI helpers can affect not only the reporting of findings – but also the person making the findings.
Malignant tumour management
’Our machine learning model achieved 88.9% accuracy in predicting the sarcoma-specific survival rate’
Clinical management of soft tissue sarcoma is particularly challenging. Dr Sebastian Foersch, researcher at the Institute of Pathology at the University Medical Center in Mainz, Germany, has used a deep learning model for diagnosis and prognosis prediction of soft tissue sarcoma using conventional histopathology slides.
CNN applications in pathology
‘Deep learning can predict survival directly from histology in clear cell renal cell carcinoma’
Renal cell carcinoma is among the fifteen most common cancers worldwide. Dr Titus Brinker, from the German Cancer Research Center (DKFZ), looked at whether a convolutional neural network (CNN) can extract relevant image features from a typical H&E-stained slide to predict 5-year overall survival.
Article • AI provides prognostic information
Next-generation deep learning models predict cancer survival
Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…
Article • Prediction for breast, ovarian, cervical, and endometrial carcinoma
New test detects four women’s cancers from cervical screening samples
What if a test analysing cervical cells from a gynaecological swab could be used to detect four different female cancers at an early stage and also predict cancer risk over a healthy woman's lifetime? Researchers at the EUTOPS Institute in Innsbruck, Austria, are developing tests to do just that for breast, ovarian, cervical, and endometrial cancer detection.
