Researchers at Cleveland Clinic, University of Oxford, and University of Erlangen have identified a novel imaging biomarker – and found it can be used to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries.
Researchers have developed a novel way for dating "hibernating" HIV strains, in an advancement for HIV cure research in the province. The HIV cure research confirms that dormant HIV strains can persist in the body for decades.
In recent years, clinicians have increasingly focused on vitamin D deficiency. Studies show that previous reference values – particularly for Vitamin D3 – were most probably set too high. Liquid chromatography with mass spectrometry (LC-MS) can help achieve more precise measurements of vitamin D levels than previously established immunoassay procedures, explains Dr Torsten Binscheck-Domass,…
Pre-analytics, in particular venous blood sampling has a major impact on the quality of laboratory diagnostic results. An estimated 75 percent of all "lab errors" are caused by errors during pre-analytics. Thus, the German Medical Association’s national guideline on laboratory diagnostics includes detailed guidance on pre-analytics, in particular venous blood sampling. In their…
The genome sequences of ape parasites related to Plasmodium vivax (P. vivax), the main source of mosquito-borne malaria outside Africa, provide insights on the origin and early evolution of the human parasite. This finding could have implications for better comprehending and eradicating malaria infection worldwide.
Experts report that a new blood test to diagnose heart attacks could be carried out on a hand-held device in the not-too-distant future. The test, devised by a team at Kings College London, uses similar technology to the troponin test, but instead analyses cardiac myosin-binding protein C (cMyC). In research presented at the British Cardiovascular Society conference in Manchester, UK, this June,…
Changes in circulating tumor DNA levels quickly predict how patients with diffuse large B cell lymphoma are responding to therapy, according to a Stanford-led study. Currently, patients wait months for the results.
A recent study, performed in Chicago and Rabat, Morocco, found that a novel finger-prick test for infection with the parasite Toxoplasma gondii during pregnancy — and many other potential applications — is 100 percent sensitive and 100 percent specific for detecting the presence of this life-damaging microorganism.
A pioneering study into myeloma, a rare cancer, could lead to General Practicianer (GPs) using simple blood tests to improve early diagnosis. The study investigated the best combination of blood tests that could be used to diagnose myeloma in GP practices.
The Thermo Scientific TSG Series of refrigerators maintain optimal cold storage conditions with minimal energy consumption and noise output. They have been specifically developed to address the need of clinical laboratories and patient care facilities for cold storage equipment that enable secure and energy-efficient storage of vaccines, medicines, lab kits and breast milk, while offering quiet…
Over the last several years, technological advancements have enabled the development of tests that can be performed right where the patient is, whether that’s in a hospital room, primary care office, or community health center. This is a paradigm shift in healthcare delivery that will make it easier for patients to get accurate diagnoses and treatment, and could especially benefit patients in…
Beckman Coulter announced commercialization of its DxM MicroScan WalkAway system, a diagnostic solution for bacterial identification and antibiotic susceptibility testing for microbiology laboratories. The DxM MicroScan WalkAway system uses direct minimum inhibitory concentrations (MIC) for detection of antimicrobial resistance, offering greater confidence in results through gold-standard…
Clinical laboratories are challenged to meet greater testing demands, improve efficiency, and deliver reliable, high-quality results, while facing an increasing shortage of skilled employees and growing budget constraints. Recognizing that technology can play a critical role in addressing each of these challenges, Siemens Healthineers brought to market the Atellica Solution immunoassay and…
In microscopy, ergonomics is particularly important as long periods at the microscope put unusually specific constraints on posture. In certain roles, such as in pathology, microscopy forms a significant part of daily activities – sometimes taking up more than 50% of working hours. Protecting operators by preventing injuries is of utmost importance in these routine microscopy roles.
The clinical performance of Beckman Coulter's high-sensitivity troponin I (hsTnI) assay Access hsTnI has been validated in a study. Within 2 hours, the assay delivers an accurate assessment of patients with suspected acute coronary syndrome (ACS).
A scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the next generation of genetic therapies.
Big Data can be a critical tool in helping clinicians develop advanced patient health risk assessment and stratification models as well as leading to a new level of patient empowerment. Professor Josep Roca outlined the benefits of Big Data in a laboratory context during the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference held in Mannheim, Germany,…
The need to do more to combat resistance in Germany was keenly emphasised by delegates at the VDGH (The German Diagnostics Industry Association) event held in Berlin this May. Only the answer, or at least the common will, is missing to bring this threat under control via a concerted concept.
The need to ensure that laboratory medicine can meet the future challenges of a rapidly changing healthcare environment sits at the core of an innovative strategic conference for this sector. The agenda of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference in Mannheim (18-19 June) highlighted the challenges, and also outlined areas of discussion to…
The idea of testing blood or urine to find markers that help diagnose or treat disease holds great promise. A new study helps set standards for RNA sequencing, improving consistency and laying the foundation to move the field forward.
A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to a smartphone, computer, or other electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology. The advance could lead to cheaper, faster and…
Imagine a pathogen that infects completely healthy people and can cause blindness in one day and flesh-eating infections, brain abscesses and death in just a few days. Now imagine that this pathogen is also resistant to all antibiotics.
Machine learning is adding a new dimension to pathology and already outperforming experts during some tasks, according to several speakers at the 14th European Congress on Digital Pathology (ECDP) who revealed up-to-date developments. However, whilst AI is set to herald a new future for digital pathology, Johan Lundin, associated professor for biomedical informatics and research director at the…
Olympus’ Image of the Year Award for light microscopy in Europe recognizes the very best in life science imaging. Inspired by the beauty and breadth of images submitted for Image of the Year 2017, Olympus is now continuing its quest for the best light microscopy art in 2018. For the chance to win one of three prizes, applicants can submit life science light microscopy images to…
Since 2013, a new strain of meningococcal bacteria has spread rapidly in Niger and Nigeria, leading to large-scale outbreaks of meningitis. Analysis of the genetic material shows that with just two gene mutations, harmless bacteria transform into a strain that could cause major epidemics in these two countries.