New research reveals that self-generated electrical activity of small cell lung cancer (SCLC) directly promotes tumor metastasis and progression. This may provide new avenues for future treatments.
For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.
There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…
Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…
Researchers developed an advanced AI tool for automatic analysis of colorectal cancer tissue slides. The new model outperformed all predecessors in the classification of tissue microscopy samples.
New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.
A new blood test, using neurofilament light chainproteins as biomarker, could lead to better diagnosis and management of amyotrophic lateral sclerosis (ALS).
New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.
MRC Holland recently announced that five SALSA MLPA assays for the detection of hereditary breast and ovarian cancer (HBOC) syndrome were recently CE-marked for in vitro diagnostic (IVD) use under the new In-Vitro Diagnostic Regulation EU 2017/746 (IVDR).
Molecular changes associated with brain inflammation and dementia can be detected in the blood. Researchers want to use this to establish blood tests as an alternative to more costly brain scans.
The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.
Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.
Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.
Microbiologists have just shown that people with diabetes are more likely to develop antibiotic-resistant strains of Staphylococcus aureus, a leading cause of AMR-associated infections and deaths.
When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.
Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.
Point-of-care diagnostics based on a combination of mobile-sized scanners and artificial intelligence (AI) are helping save the lives of women in low-resource settings. The AI technique is being applied in Kenya and Tanzania to deliver screening for cervical cancer – now the leading cause of cancer-related deaths in women in that region and a bigger cause of death than childbirth.
A new blood test that detects a specific brain protein may help doctors determine the type of a stroke faster and allow them to start safe treatment for people before they get to the hospital.
Two recent studies find that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.
Europe has been polio-free since 2002 – but a recent surge in poliovirus detections across several European countries shows that the threat from this vastly-forgotten disease is over, warn experts.
Researchers have clinically validated a previously developed urine test for prostate cancer screening, which can potentially bypass invasive procedures among men who are unlikely to benefit.
Helping the brain repair itself after a stroke: A new study based on unique tissue samples from Denmark's Brain Bank may pave the way for new treatments that support brain regeneration.
Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.
A new study has shown that the molecular signature of long Covid can be found in blood samples of children. Using an AI tool, the researchers were capable of diagnosing the condition with 93% accuracy.
Self-reported, persisting health problems after Sars-CoV-2 infection are commonly described. However, the long-term prognosis of post-Covid-19 syndrome is unknown. A new study aims to change this.
