Cancer metastasis is responsible for at least two-thirds of cancer deaths. Researchers have developed a multi-organ chip that mimics how cancer cells spread to distant organs to gain new insights.
New research has identified a previously unknown mechanism of Kabuki syndrome, a rare genetic disorder. The discovery could open new therapeutic perspectives.
Researchers identified a possible biomarker linked to severe suicidal thoughts. It may also help explain why some people recover, opening a new path for research into resilience and prevention.
Blood tests yield vital information about Alzheimer’s disease. However, new research suggests that relevant biomarkers may differ significantly across patient populations.
Digital pathology and spatial omics could enable researchers to see how a tumor's different cell populations function, opening new perspectives for precision cancer therapy.
In a first for the field, a team has grown heart valves on organoids. This work is an important step toward better understanding—and treating—a number of serious heart disorders.
More biomarkers for better insights on Alzheimer's disease: a new study explores how a panel of seven proteins could help predict disease progression and inform more accurate treatment choices.
Invasive fungal infections are notoriously hard to catch early, and even harder to rule out with confidence. At CHU Bordeaux, Dr Frédéric Gabriel has spent years refining how his lab uses β-D-glucan (BDG) testing to sharpen that judgement call – including with the Wako β-glucan test. In this interview, he explains what the guidelines say, what actually happens at the bench, and where he…
Perfectly viable medical devices disappearing from the European market, manufacturers walking away from the EU rather than navigating regulatory demands, patients losing access to products with long, well-documented safety records. The implementation process for the MDR and IVDR has been challenging, to put it mildly – and the journey is far from over. Ahead of the EAAR’s MDR/IVDR Summit…
A new study links metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) to an elevated risk of cardiovascular disease, cognitive decline, and other metabolic complications.
A common diabetes test could miss the condition in people with sickle cell trait, new research suggests. Understanding this limitation of immunoassay testing could help guide protocols and policies.
In a study, researchers found unusually high levels of urea in the brains of people with frontotemporal dementia and ALS. The findings raise questions about how the brain clears harmful substances.
Researchers have developed a method to enhance the cellular features in pathology slides based on “structural color” – the same effect that gives peacock feathers their unique sheen.
Detecting genetic mutations associated with lung cancer via laboratory tests can be expensive and time-consuming, and use up valuable tissue from small biopsy samples. A new approach aims to fix this.
The presence of certain bacteria in the gut microbiota, and fluctuations in a person’s metabolism, have been identified as potential biomarkers for type 2 diabetes years before its onset.
Adenomyosis can cause heavy menstrual bleeding, severe pain, and pregnancy and fertility complications. New research could help pave the way for more targeted, less invasive treatments.
A blood test for ctDNA may help identify which patients with colorectal cancer that has spread to the liver are most likely to benefit from chemotherapy after surgery, according to new research.
The microbes living in the human gut influence metabolism, immunity, and cardiovascular health. A new study now suggests they may also be closely connected to Alzheimer's disease.
Slower recovery, more complications, longer monitoring: People with diabetes face considerably worse long-term effects after a coronavirus infection – also known as long Covid, a new study shows.
Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.
Asthma attacks induce mechanical forces that permanently alter airway tissue – independently of inflammation. New research used advanced lung-on-a-chip technology to show how this damage occurs.
Researchers have developed a new lab model to study BAP1-deficient melanomas, a rare type of melanoma that evade the immune system once they metastasize and are resistant to current immunotherapies.
A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy — a fundamental breakthrough.
AI is transforming the way cancer is diagnosed and treated. Dr Yuri Tolkach shared his group's advances in developing AI-based tools for oncological pathology at the DPAI Europe congress.
At which point does Alzheimer’s disease pathology lead to dementia? Researchers identified distinct mechanisms in the brain, which could represent an important target for future therapies.
