Search for: "flow cytometry" - 27 articles found

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The stronger sex after all

Why women may be better equipped to fight Covid-19

When it comes to Covid-19, women seem to be the stronger sex, suffering severe disease at about half the rate as men, but the reason for this has been elusive. Now a chance experiment by an ophthalmology researcher at Duke Health has led to an insight: Women have more of a certain type of immune cell that fights infections in mucosal tissue, and these immune cells amass in the lungs, poised to…

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Quality aspects

Lab automation – economic aspects and Covid-19

The academic teaching Karlsruhe Hospital, at the University of Freiburg, is the largest hospital providing tertiary care in the Middle Upper Rhine Valley. Every year, 63,000 in-patients and 180,000 out-patients are treated in the 1,500-bed facility with 50 departments and 30 out-patient clinics. Inevitably, a hospital of this size has a central lab. We spoke with Dr Horst Mayer, managing senior…

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Blood poisoning

Exploring the importance and challenges of early sepsis diagnosis

On the occasion of this year's World Sepsis Day, we spoke with Elena Sukhacheva, Ph.D., director of medical and scientific affairs at Beckman Coulter, about the status quo and outlook on sepsis diagnostics. With the severity of sepsis symptoms, it’s easy to comprehend why it is invaluable to diagnose this disease properly and in a timely manner. Dr Sukhacheva takes an in-depth look at…

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Oncology

How cancer spreads in blood

A new study sheds light on proteins in particles called extracellular vesicles, which are released by tumor cells into the bloodstream and promote the spread of cancer. The findings suggest how a blood test involving these vesicles might be used to diagnose cancer in the future, avoiding the need for invasive surgical biopsies.

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Dry Unitized Reagent Assays

Beckman Coulter presents online cost benefit tool at AACC 2019

Beckman Coulter Life Sciences launched the online DURA Innovations calculator tool, a powerful cost benefit analysis resource to accompany its latest Cost Benefit Calculator Handbook. The free online tool enables laboratories to quantify the value of converting to a standardized flow cytometry workflow using the company’s dry reagent technology. The new calculator enables customers using liquid…

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Biomedical engineering

Cornea restoration: Scientists develop physical biomarker

Our eyes – considered by many to be the windows to the soul – need constant care, and as we age, they sometimes also need significant repair. The panes of these windows – the corneas – are transparent tissues that have been the focus of some of the oldest and most common transplantation surgeries. Now thanks to researchers in Kyoto, some such transplants may become even safer. The team,…

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Flow cytometry

Living cells – the essential biomarker

The team of the Heinz Nixdorf Chair of Biomedical Electronics at the Technical University of Munich focuses on innovative diagnostic tools to accelerate the development towards personalized medicine. Therapies tailored to the individual patient – this is the future not only of oncology but of many medical disciplines. “At this point, however,” concedes Professor Dr Oliver Hayden,…

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Hematology

Early sepsis indicator helps identifying patients at risk

The critical element of testing for sepsis lies not so much in the location but in the timing and rapidity of results, according to Professor Jeannine T. Holden from Beckman Coulter Early identification enables treatment protocols to be delivered more quickly, offering better patient outcomes. Those most at risk, suggests Holden, are not patients within the intensive care unit – who are already…

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Sysmex

With the UN-Series, the choice is yours

Using urine to obtain diagnostic insights has been done for thousands of years and still remains an important tool to obtain crucial information. Covering a range of tests, urinalysis may be used to screen for or help to diagnose ailments such as urinary tract infections, kidney disorders, liver problems, diabetes or other medical conditions, just to name a few. Because urinalysis has been around…

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Flow cytometry lab

New ClearLLab IVD Reagents launched

Beckman Coulter is launching the ClearLLab 10C System for the clinical flow cytometry lab. The new system is the first 10-color IVD panel of immunophenotyping reagents cleared by the Food and Drug Administration (FDA) for both lymphoid and myeloid lineages. The four dry pre-mixed antibody tubes use the company’s DURA Innovations technology, eliminating the need to pipette antibodies, improving…

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Evolving technique

Flow cytometry rises to new challenges

Flow cytometry has proved an invaluable diagnostic tool for leukaemia and lymphoma for almost three decades. Now, however, this is evolving in applications to seek out residual disease in cases and in fusion with molecular testing to advance its diagnostic potential. However, although recognised as fast, flexible and accurate, flow cytometry suffers from a lack of standardisation, according to…

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Innovation

Hematology: Advancements and future trends

While the role of the laboratory in disease diagnosis and management has expanded in recent years, causing an overwhelming rise in testing demands, the availability of skilled technologists and specialists has been diminishing. To meet the needs of an overworked and increasingly generalized workforce, today’s products not only must deliver more clinical data than ever before, but also must be…

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High-throughput system

Speeding up flow cytometry to discover new drugs

A new SLAS Discovery original research article available now for free ahead-of-print, researchers from the Genomics Institute of the Novartis Research Foundation (GNF) highlights a diversity of approaches that their automated high-throughput flow cytometry has enabled for phenotypic drug discovery. Flow cytometry is a very powerful tool that has been used for decades and allows for…

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Medical technology

Genrui presents latest products

Genrui Biotech Inc., one of the leading Chinese developers and manufacturers of IVD equipment and reagents, present their latest POCT devices at the China International Medical Equipment Fair (CMEF). Among the presented devices are the 5-Part Auto Hematology Analyzer KT-6610, which uses advanced tri-angle laser scattering, flow cytometry technology to deliver white blood cell differential…

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Equipment

A tiny, more cost-effective white blood cell counter might be available soon

A thin copper wire wrapped around a channel slightly thicker than a strand of hair could be the key to manufacturing a compact electronic device capable of counting white blood cells from the comfort of one’s home, a Kennesaw State University researcher says. Hoseon Lee, an assistant professor of electrical engineering in the Southern Polytechnic College of Engineering and Engineering…

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Value based lab medicine

Meeting the challenge of modern laboratory demands

Faced with the constant challenge of increasing demand and a backdrop of falling reimbursement, Mayo Clinic in the United States has adopted an innovative and proactive approach to managing its laboratory services. That has seen the US-based medical giant embrace a variety of tools and reference materials to aid clinician decision making, improve care and lower costs. Dr Curt Hanson, Chief…

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Improved workflow

UK uptake increases in digital pathology

Professor Jo Martin, the newly-appointed President of the Royal College of Pathologists in the United Kingdom, believes the National Health Service (NHS) is on the brink of embracing digital pathology more widely. A number of UK laboratories, he explained, are adopting digital pathology in histopathology – in line with some labs in Sweden and Holland, where it has become routine – and the…

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Achieving a faster workflow

A modular approach to urinalysis

The reasons why doctors request urinary analysis are varied – perhaps to detect a possible or suspected infection, or to screen for kidney diseases. In all cases a reliable and rapid result is the major aim. Urinary microscopy and culture have been the mainstays of urinary analysis for many, many years both of which require time and specialist handling.

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Hematology

Shaping the advancement of healthcare

Our mission at the Sysmex Corporation is defined very clearly in our corporate policy: in all that we do, our focus must be on Shaping the Advancement of Healthcare. Of course, there are a million mission statements out there, with all underlying companies claiming that they will change the world in which they operate. Words can come cheap. But not at Sysmex. By the simple fact that we are the…

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Curse or blessing?

A small prick to sample blood instead of complex pathological or other diagnostic procedures – this is how early cancer diagnosis will be in the near future. Blood tests to diagnose tumorous diseases early are already being researched for clinical use.

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PET/MR: The opportunities are almost unlimited

MRI has become the gold standard for many indications in cardiac imaging, apart from imaging the coronary arteries. For function and morphology assessment, MRI is the leading technology. A further advance into as yet unknown territory is myocardial imaging aided by one of the first integrated 3-Tesla PET/MR systems currently used at the Institute of Radiology, Essen University Hospital,…

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