News • Fluorescence assay
A 'FAIRY' to rapidly determine virus infectivity
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
Search for: "zika" - 74 articles found
News • Public health research
Climate change brings new diseases to Europe – using AI to prepare
Due to climate change, diseases such as West Nile fever reach European countries. With the help of AI and math, institutions can prepare for new infections in the changing climate, new research shows.
Article • Latest advances
Lab-on-a-chip systems in 2023: The micro-lab revolution
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
News • Covid-19
Preparing for another outbreak
What will the next pandemic look like? Health officials from across the globe gathered in Geneva in late August at a World Health Organization meeting to focus on how lessons learned from Covid-19 might best prepare civilization for the "next one."
Article • Modelling systems for human biology
Organoid technology: new opportunities for drug discovery
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
News • Greenhouse gas emissions
How climate change impacts human pathogenic diseases
A comprehensive assessment of scientific literature has uncovered empirical evidence that more than 58% of human diseases caused by pathogens, such as dengue, hepatitis, pneumonia, malaria, Zika, have been aggravated by climatic hazards.
Interview • Global warming awareness
Showing health implications of climate change is best way to reach public
John Kotcher from George Mason University says that emphasizing the health implications of climate change is one of best ways to engage the public to fight for better policies.
News • Without causing neurological damage
Injections of zika virus destroys brain tumors
In both the mice and organoids, cytokines suppressed tumor growth after treatment, and defense cells migrated to the brain region affected by the tumor, alerting the immune system to its existence.
News • Potential game-changer
Telling COVID-19 apart from influenza
Researchers have developed a diagnostic for SARS-CoV-2 that is capable of differentiating between COVID-19 and the garden-variety bug with fast turnaround.
Article • Point-of-care testing
Emerging technologies in POCT
Considerable advances in point-of-care testing (POCT) devices are emerging from lab-on-a-chip platforms, innovations in smartphone-based technology and wearable technology. Cloud-based deep learning systems herald a future revolution.
News • Coronavirus disease biomarkers
New Covid-19 testing method gives results within one second
The Covid-19 pandemic made it clear technological innovations were urgently needed to detect, treat, and prevent the SARS-CoV-2 virus. A year and a half into this epidemic, waves of successive outbreaks and the dire need for new medical solutions — especially testing — continue to exist. In the Journal of Vacuum Science & Technology B, researchers from the University of Florida and…
News • "Faces" of the disease
Covid-19: researchers identify at least 5 variants
According to current studies, the Covid-19 disease which is caused by the SARS-CoV-2 coronavirus comprises at least five different variants. These differ in how the immune system responds to the infection. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, together with other experts from Germany, Greece and the Netherlands, present these findings…
Article • AI, apps and more
Digital health tools to fight Covid-19
A great deal of solutions using new technologies have been released to help tackle the Covid-19 pandemic and a panel of international experts shared a few examples during the Barcelona Health Summit last October. Contact-tracing apps are an interesting option to manage a pandemic, but the creation process can take a long time and must meet several requirements, according to a Dutch official who…
News • Genome sequence analyzer app
Researchers build world’s first DNA “tricorder”
Cold Spring Harbor Laboratory (CSHL) scientists developed the world’s first mobile genome sequence analyzer, a new iPhone app called iGenomics. By pairing an iPhone with a handheld DNA sequencer, users can create a mobile genetics laboratory, reminiscent of the “tricorder” featured in Star Trek.
News • Commonly used antibiotic
Methacycline shows promise for combating Zika infections
In a preclinical study, NIH scientists found that the commonly used antibiotic methacycline may be effective at combating the neurological problems caused by Zika virus infections.
News • Zika and chikungunya
Mosquito-borne viruses could cause stroke
A deadly combination of two mosquito-borne viruses may be a trigger for stroke, new research published in the The Lancet Neurology has found. University of Liverpool researchers and Brazilian collaborators have been investigating the link between neurological disease and infection with the viruses Zika and chikungunya. These viruses, which mostly circulate in the tropics, cause large outbreaks of…
News • COVID-19
‘Mini-Brains’ suggest SARS-CoV-2 can infect brain cells
Scientists have found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as “mini-brains” can be infected by the SARS-CoV-2 virus that causes COVID-19.
News • Coronavirus misinformation
Experts find COVID-19 fake news in 1 of 4 most popular YouTube videos
More than one in four of the most viewed COVID-19 videos on YouTube in spoken English contains misleading or inaccurate information, reveals the first study of its kind, published online in BMJ Global Health. Public health misinformation on COVID-19 is reaching far more people than in previous pandemics and has considerable potential for harm, warn the researchers. While good quality accurate…
Video • Epidemiologist Q&A
12 things you should know about the new coronavirus
The novel coronavirus that recently originated in Wuhan, China has grabbed headlines and caused concern among public health officials around the world. Two infectious disease experts share their insights on the novel coronavirus epidemic.
News • Why do we get sick?
Mechanism behind development of viral infections uncovered
A team of researchers from the SingHealth Duke-NUS Academic Medicine Centre’s Viral Research and Experimental Medicine Centre (ViREMiCS) found that immune cells undergoing stress and an altered metabolism are the reasons why some individuals become sick from viral infections while others do not, when exposed to the same virus. The findings, published in medical journal Nature Medicine, have…
News • Global health
WHO updates list of essential medicines and diagnostics
The World Health Organisation's (WHO) Essential Medicines List and List of Essential Diagnostics are core guidance documents that help countries prioritize critical health products that should be widely available and affordable throughout health systems. Now, updated versions of the two lists have been published, focusing on cancer and other global health challenges, with an emphasis on effective…
News • Gene-editing
CRISPR baby mutation significantly increases mortality
A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life, according to an analysis by scientists from UC Berkeley. The researchers scanned more than 400,000 genomes and associated health records contained in a British database, UK Biobank, and…
Article • Blood transfusions
Donor organs become immunologically invisible
The safety of blood transfusions is questioned again and again by the mass media. Sometimes ‘bad’ blood causes infections; sometimes a transfusion leads to cancer years later. The fact is that transfer blood is subjected to the highest safety standards – there are very clear statutory regulations. Nonetheless, there will be shortages of ‘life’s fluid’ because, given increasing…
News • Infectious disease
Sensor technology could detect Dengue fever earlier
Researchers from the University of Bath are developing a new tool for detecting the presence of Dengue fever early on, helping prevent people from suffering potential life-threatening complications.
News • Inexpensive invention
Test kit enables quick and accurate screening of diseases
Test results are denoted by a colour change and could be further analysed by a smartphone app, making it attractive as a point-of-care diagnostic device.
News • Infections
Zika virus strips immune cells of their identity
Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.
News • Research
Zika virus proteins inhibit brain development
In healthy individuals, the Zika virus causes flu-like symptoms. If a pregnant woman becomes infected, the unborn child can suffer from severe brain abnormalities as a result of mechanisms that have not yet been explained. A study by the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry (MPI-B) shows that Zika virus proteins bind to cellular proteins that are…
News • Infections
Zika suppresses virus fighting cells
More than two years after reports of skyrocketing Zika rates surfaced worldwide, questions still loom about this complicated virus. Professor of Biological Science Hengli Tang and his postdoctoral researcher Jianshe Lang from the Florida State University take a deep dive into the differences between Zika and the Dengue virus.
News • Epidemics
Animal health drug could stop outbreaks of malaria and Zika virus
Medicines given to household pets to kill fleas and ticks might be effective for preventing outbreaks of malaria, Zika fever and other dangerous insect-borne diseases that infect millions of people worldwide, according to a new study led by scientists at Calibr, a non-profit drug discovery institute closely affiliated with Scripps Research and TropIQ Health Sciences, a Dutch social enterprise.
Video • Wolbachia
Little-known bacteria might grind Zika and dengue infections to a halt
A Vanderbilt team took the next leap forward in using a little-known bacteria to stop the spread of deadly mosquito-borne viruses such as Zika and dengue. Wolbachia are bacteria that occur widely in insects and, once they do, inhibit certain pathogenic viruses the insects carry. The problem with using Wolbachia broadly to protect humans is that the bacteria do not normally occur in mosquitoes…
News • Risk for pregnancy
How Zika infection drives fetal demise
A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy. When exposed to Zika virus before birth, mouse fetuses with the protein commit cell suicide, while fetuses without it continued to develop. The result, published in Science Immunology, suggests that the protein, a receptor involved in immune cell signaling, plays a role in spontaneous abortions and other human…
News • Blood Donor Month
Things you should know about blood donation
Donating blood is a tangible way to help people who are struggling with serious health conditions, yet many people may not think about it or make time for it. In January – which the American Red Cross has dubbed National Blood Donor Month – blood bank supplies are typically among the lowest of the year, as many people have been traveling or busy with the holidays. Inclement weather can also…
Sponsored • Augmenting antibody services and assay development
Acquisition: BBI gains MBS
BBI Solutions (BBI), immunoassay developer and reagent supplier, acquired Maine Biotechnology Services Inc. (MBS) in July 2017, adding antibody development to the firm’s end to end assay development services. This also strengthens BBI’s reagents antibodies portfolio, providing a wide range of high quality biomarkers for infectious disease.
Article • DNA modification
CRISPR/Cas9 and Sherlock: Savers, healers or threats to life?
Modifying a DNA sequence to alter a cell to cure a disorder, prevent a genetic disease being passed on to next generations, or to use genetic modification as a way to diagnose a virus: yes, these tasks are possible. The recently discovered CRISPR technique can do it all.
News • Study
Zika virus could be used to treat brain cancer
Recent outbreaks of Zika virus have revealed that the virus causes brain defects in unborn children. But researchers from Washington University School of Medicine in St. Louis and the University of California, San Diego report that the virus could eventually be used to target and kill cancer cells in the brain.
Article • Diagnosing Zika
Commercial blood test proves reliable
The Society for Virology (GfV) which promotes virology through the increase and exchange of research within German speaking countries, as well as via cooperation with other scientific societies, announced this year that a new test can unambiguously confirm the diagnosis of a Zika virus infection – leading to fast diagnosis and identification of an infection.
News • Virus study
Close contact not at fault for Zika spread
Saliva is no way to pass a Zika virus infection. According to researchers at the University of Wisconsin–Madison who conducted studies with monkeys, casual contact like kissing or sharing a fork or spoon is not enough for the virus to move between hosts.
Article • Infection control
Zika-vaccine receives boost
A promising Zika vaccine is on its way. Themis Bioscience GmbH (Vienna, Austria), a company specialised in vaccine development, has announced that the firm will receive One milion pounds sterling in funding by the innovation agency of the United Kingdom, Innovate UK, for the further development of this prophylactic vaccine and the conducting of a Phase 1 clinical trial.
News • Prevailing colds
No summer vacations for viruses
Summer colds might seem rare, but people are actually just as likely to catch one in the summer as in the winter.
News • Outbreaks
Ebola: New management approach can save lives
Ebola outbreaks are set to be managed quickly and efficiently – saving lives – with a new approach developed by an international team of researchers, including the University of Warwick, which helps to streamline outbreak decision-making.
Article • Infection control
Global warming: Science can only react to emerging diseases
The ‘Transmission, Prevention, and Reporting of Emerging Infectious Diseases’ program for the International Conference IMED 2016 in Vienna, this November, reflected events in the field of emerging diseases that have occurred over the last two years. Therefore, key congress topics included the Zika virus, the effects of global warming and the unusually high number of hospital-acquired…
Article • Pandemic planning
The world is underprepared for infectious diseases
A team of international experts has highlighted how the world remains ‘grossly underprepared’ for infectious disease outbreaks, which are likely to become more frequent in future decades.
Interview • Infection control
Virologists are today’s universal necessities
Globalisation has been a defining term in this 21st century: with almost anybody able to visit any place at any time, diseases, viruses and bacteria can be travel companions. Thus virology is gaining increased attention. Professor Barbara Gärtner, President of the German Association of Virology, talks about the issues and challenges arising from this development.
Article • Imaging Infections
Zika birth defects decrease, but…
ECR 2017 Guest Lecturer Maria de Fatima Vasco Aragao, a radiologist from Pernambuco state, Brazil, has been tracking the Zika virus ever since it broke out in her country in 2015. She will highlight how CT and MRI can help reach diagnosis, especially in the absence of microcephaly. In an exclusive interview with European Hospital correspondent Mélisande Rouger, the radiologist warned there might…
Article • Infections
Science can only react
The ‘Transmission, Prevention, and Reporting of Emerging Infectious Diseases’ programme for the International Conference IMED 2016 in Vienna, this November, reflected events in the field of emerging diseases that have occurred over the last two years.
News • Infections
World still “grossly underprepared” for infectious disease outbreaks
The world remains “grossly underprepared” for outbreaks of infectious disease, which are likely to become more frequent in the coming decades, warn a team of international experts in The BMJ today.
Article • Frontline medical advances
Virology is now a key discipline
Virology is fast emerging as a key discipline within modern healthcare against a backdrop of a shifting global demographic and the impact of climate change.
Interview • Zika infections subside
‘I would travel to South America any time,’ virologist confirms
In Europe, the first baby with Zika-related microcephaly was born in July. The mother had contracted the Zika virus while travelling in America. How dangerous is the virus for Europeans, particularly since many visited Brazil for the Olympic Games in Rio?
Altering the ‘flavor’ of humans could help fight Malaria
A new study by Johns Hopkins researchers suggests that a specialized area of the mosquito brain mixes tastes with smells to create unique and preferred flavors. The findings advance the possibility, they say, of identifying a substance that makes “human flavor” repulsive to the malaria-bearing species of the mosquitoes, so instead of feasting on us, they keep the disease to themselves,…
News • Infection
Evidence of Zika virus found in tears
Researchers have found that Zika virus can live in eyes and have identified genetic material from the virus in tears, according to a study from Washington University School of Medicine in St. Louis. The research, in mice, helps explain why some Zika patients develop eye disease, including a condition known as uveitis that can lead to permanent vision loss.
News • dormant viruses
Researchers Find Herpes Strain in the Nervous System
There are a couple strains of herpes so common that researchers estimate 90% of the human population have them. These strains, human herpes 6 and human herpes 7, usually do not cause severe symptoms when people acquire them. But researchers know that under certain circumstances, dormant herpes viruses in the body can unexpectedly come roaring back and cause complications not typically associated…
News • Study
Link between Zika virus and severe joint condition at birth?
A study published by The BMJ provides more details of an association between Zika virus infection in the womb and a condition known as arthrogryposis, which causes joint deformities at birth, particularly in the arms and legs.
News • Infection
Antibodies identified that thwart Zika virus
Scientists at Washington University School of Medicine in St. Louis have identified antibodies capable of protecting against Zika virus infection, a significant step toward developing a vaccine, better diagnostic tests and possibly new antibody-based therapies. The work, in mice, helps clarify recent research that also identified protective Zika antibodies but lacked important details on how the…
News • Infection
Zika: 1.6 million childbearing women are at risk
Research by scientists in the US and UK has estimated that up to 1.65 million childbearing women in Central and South America could become infected by the Zika virus by the end of the first wave of the epidemic. Researchers from the WorldPop Project and Flowminder Foundation at the University of Southampton and colleagues from the University of Notre Dame and University of Oxford have also found…
News • Lab-on-a-Chip
Breakthrough aims to help physicians detect cancer at nanoscale
IBM scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale and could enable physicians to detect diseases such as cancer before symptoms appear.
News • Infection
Siemens Zika test receives FDA emergency use authorization
The U.S. Food and Drug Administration (FDA) has granted Siemens Healthcare Diagnostics Inc. (Siemens) an Emergency Use Authorization (EUA) for its real-time PCR Zika Virus assay, the VERSANT® Zika RNA 1.0 Assay (kPCR) Kit. With respect to Zika in vitro diagnostic tests, FDA has been authorized to issue EUAs to allow for use of unapproved medical products or unapproved uses of approved medical…
Article • Difficult foe
Clostridium difficile: Fresh insight into an old pathogen
Hospital-acquired Clostridium difficile infection (CDI) is on the rise. Symptoms range from non-typical mild diarrhoea that can develop into pseudomembranous colitis up to a toxic megacolon, which often leads to death.
News • Experts
Europe needs to be prepared for Zika virus epidemic
The Zika epidemic has long assumed global proportions, experts told the Congress of the European Academy of Neurology in Copenhagen. Europe needs to get prepared to deal with the relentless spread of the health threat, in particular with a view to “imported” infection. Awareness for prevention and personal protection is important, in particular with thousands of athletes and fans soon…
News • Epidemic
Global spread of Zika "of utmost concern"
The President of the World Federation of Neurology (WFN) Prof Raad Shakir (London), said today that following the first confirmed Zika-related case of microcephaly on US territory, in Puerto Rico, and the ever-growing number of sexually-transmitted Zika infections in Europe, “it is increasingly obvious that the Zika epidemic has long assumed global proportions.” As the opening of the Olympics…
News • Research
Zika: Experimental drug slows down infection
Virologists from KU Leuven, Belgium, have shown that an experimental antiviral drug against hepatitis C slows down the development of Zika in mice. The research team was led by Professor Johan Neyts from the Laboratory of Virology and Chemotherapy.
News • Epidemics
Open Science to track virus outbreaks
In recent years, we have witnessed multiple epidemics of viral diseases such as Ebola or Zika. Rapid targeted intervention is key to containment. Real-time data integration and analysis can help public health authorities to maximize efficacy of intervention strategies. Dr. Richard Neher from the Max Planck Institute for Developmental Biology, Germany and Dr. Trevor Bedford from the Fred…
New technology breakthrough in fighting viral diseases
As one of medicine’s largest challenges, viral infections often escape vaccines due to their natural ability to mutate rapidly and develop drug resistance easily. Many viruses, such as Zika, Ebola and dengue fever, have grown into major global health epidemics with great human and economic toll. IBM Research and Singapore’s Institute of Bioengineering, Nanotechnology (IBN) announced they have…
News • Leishmaniasis
Prevent global outbreak with vaccine for deadly parasitic infection
As scientists scramble to get a Zika virus vaccine into human trials by the end of the summer, a team of researchers is working on the first-ever vaccine to prevent another insect-borne disease – Leishmaniasis – from gaining a similar foothold in the Americas.
‘Mini-Brains’: Evidence of Zika’s toll on fetal cortex
Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex.
Interview • Viruses
Measles, mumps, rubella threaten youngsters
Before his presentation at ECCMID 2016, Dr Guillaume Béraud, Infectious Disease Specialist, in the Centre Hospitalier Universitaire de Poitiers, Poitiers, France, talked to European Hospital about the results from his modelling of these three “childhood” diseases measles, mumps and rubella.
News • Rio de Janiero
First description of 2015 Zika virus outbreak
Since the recent link to severe neurological defects in infants born to mothers infected during pregnancy, Zika virus (ZIKV) has become a public health and research priority. A study reports details from the 2015 Zika outbreak in Rio de Janeiro - the first with a high proportion of cases confirmed by molecular diagnosis - and proposes changes to the current diagnostic criteria for ZIKV disease.
News • Neurology
Zika virus may now be tied to another brain disease
The Zika virus may be associated with an autoimmune disorder that attacks the brain's myelin similar to multiple sclerosis, according to a small study that is being released today and will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.
News • ECCMID 2016
Pioneering research abstracts on colistin resistance and migrant health
The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores risks, knowledge sharing and best practices in the fight against infectious disease – has received more than 300 late-breaker abstract submissions for its annual congress, ECCMID 2016 in Amsterdam.
Article • Virus
The Zika mystery: scapegoat or villain?
From the beginning the accusation somehow beggared belief. A ‘mild’ virus was blamed for causing hideous malformations in babies’ heads. Brazil, a country suffering its worst recession since the 1930s, as well as political upheaval, became the focus of a worldwide healthcare scare.
News • Rapid testing
West Africa, Ebola and the threat of Zika
Rapid testing for the Zika virus is a critical need in the recent Ebola-affected countries of Liberia, Sierra Leone and Guinea, says a Georgetown University professor, because of the recent Zika outbreak on nearby Cape Verde and the similarity in symptoms between Zika and early Ebola.
News • Protective and human-derived
Successful isolation of a antibody against Ebola
Humabs BioMed SA and the Institute for Research in Biomedicine (IRB) affiliated to the Università della Svizzera italiana announced the identification, isolation and characterization of two Ebola virus neutralizing monoclonal antibodies from the blood of a survivor of an Ebola infection.
News • Infections
Zika virus 'a game changer' for mosquito-borne diseases
The Zika virus, unlike other mosquito-borne viruses such as dengue, is relatively unknown and unstudied. That is set to change since Zika, now spreading through Latin America and the Caribbean, has been associated with an alarming rise in babies born in Brazil with abnormally small heads and brain defects – a condition called microcephaly.
News • Zika virus
ESCMID experts gather data to prepare for potential outbreaks
Experts at the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) – an organization promoting research, risk assessment, knowledge sharing and best practices in the fight against infectious diseases – are developing tools to monitor the spread of the Zika virus and are conducting research to gather more solid data to better assess the risks associated with the…
News • Zika virus
Nurses are first point of care for education and community resilience
As the largest group of health professionals in the world, and the first point of care for many, nurses are key to educating patients on prevention and risk of the Zika virus and providing care to those who need treatment.