Laboratory/Pathology • healthcare-in-europe.com

Rapid and robust PCR testing for infectious diseases at Innklinikum Altötting and Mühldorf

The Covid-19 pandemic has highlighted the importance of the fast and accurate diagnosis of infectious diseases in clinical settings. Harald Maier discusses the implementation of rapid molecular diagnostics in the central clinical diagnostics laboratory at Innklinikum Altötting and Mühldorf, highlighting how the use of PCR testing has benefitted the hospital during the Covid-19 pandemic.

News • Cell production changes as an early warning

Blood test could predict future risk of leukaemia

A blood test could predict risk of developing leukaemia in the elderly population years in advance by identifying changes in blood cell production, according to new research.

News • Coronavirus research

How the Omicron variant dodges the immune system

By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from Geneva reveals the exceptional capacity of Omicron to evade our immunity.

News • Nanometer-scale imaging

Microscopy technique enables 3D super-resolution

Research team led by Göttingen University combine two techniques to achieve isotropic super-resolution imaging.

News • Nanochannels

Groundbreaking: Nanofluidic scattering microscopy

To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.

News • Vortex fluidic device

Next step in rapid diagnostics for infectious diseases

The speedy, high-tech method of inexpensive, accurate and high-throughput protein biomarker assay testing is being touted as a much-needed development in point-of-care (PoC) testing.

Article • Patient-based real-time approach

PBRTQC: improving quality control in the lab

Implementing patient-based real-time quality control (PBRTQC) protocols within the laboratory testing setting can offer benefits in terms of patient safety and reducing risks.

Veros™ COVID-19 test now available in Europe

Handheld, instrument-free test delivers lab-quality molecular results – 97.9% accuracy – in about 15 minutes, right at the point of care.

News • Prevention improvement

Bowel cancer: most cases diagnosed outside of screening programmes

More than 70% of patients with bowel cancer are not diagnosed using screening programmes meaning diagnoses are often made late, when the cancer is at an advanced stage, according to new research.

News • Biomarker from blood test

Lung cancer: Liquid biopsy accurately predicts immunotherapy response

A simple blood test could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure.

News • New treatment approach

'Self-destructing' parasite: The solution for drug-resistant malaria?

Over the last 50 years, malaria parasites have developed resistance to seven drugs, but a new way to identify future antimalarials holds promise.

News • HCC in vitro research

Organoids give new clues to liver cancer progression

Newly engineered in vitro tumour models open ways to better understand the crosstalk between liver cancer cells and their microenvironment, researchers from Singapore found.

Video • Vacuette® Evoprotect Safety Blood Collection Set

The gentle touch: The next evolution of safety

Vacuette® Evoprotect is a user-friendly butterfly needle with an optimised design. The extra-thin walls have a positive effect on the flow rate and thus the duration of blood collection/infusion.

News • Macrophages

Hunting for immune cells that predispose people to severe Covid-19

When a virus makes its way into the body, one of the immune system’s first responders is a set of pathogen-removal cells called macrophages. But they don’t all target viruses in the same way.

News • Lung cancer

A novel AI for digital pathology analysis

Researchers from Boston University School of Medicine have developed a novel artificial intelligence algorithm to assess digital pathology data.

News • Low-cost

Paper-based microfluidics enables rapid prototyping

Researchers have developed a novel way to fabricate diagnostic devices using paper-based microfluidics that can be rapidly prototyped and scaled for manufacturing.

News • Protein malformation

Covid-19: immune reaction may cause amyloid generation

In patients with serious and long-term Covid-19, disturbed blood coagulation is often observed. Now, Swedish researchers found a connection between harmful amyloid production and Covid-19 symptoms.

Article • Glioblastoma analysis

Revealing tell-tale signs of deadly brain cancer

A new way of differentiating healthy from diseased cells could pave the way for more personalised treatment for patients diagnosed with glioblastoma multiforme (GBM), a common and aggressive type of brain tumour.

Article • Detection and diagnosis of cancer

The ‘smart’ future of cytology

A combination of digital pathology and quantitative biomarker analysis in the emerging concept of ‘smart’ cytology has a potential role in the detection and diagnosis of cancer.

New test with simplified preanalytics for simultaneous detection of GDH and toxins of Clostridioides difficile in compliance with recommendations

Sofia 2 C. difficile FIA is a new solution to provide reliable and rapid test results with high clinical relevance before empiric therapy decisions are implemented.

News • mhealth

Smartphone-powered microchip for at-home diagnostic testing

Researchers developed a new microfluidic chip with broad applications for detecting viruses, pathogens, bacteria and other biomarkers in liquid samples.

Article • NPIC network

Pathology in North England goes digital

Reaching out across 15 hospitals and a population of six million people, a network established by the National Pathology Imaging Co-operative (NPIC) is an ambitious move to advance digital pathology in the North of England.

News • HHV awaken via microRNA

Why herpes keeps coming back

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA, Würzburg researchers discovered.

News • Analytical performance assessment

Assay for rapid D-dimer quantification validated in independent study

In a new study, scientists from the Hematology Department, University Hospital of Clermont-Ferrand, have successfully evaluated the analytical performance of the Yumizen G DDi 2 hemostatic immunoassay.

Article • Antimicrobial resistance development

AMR and climate change: a worrying dual threat to global health

Climate change and antimicrobial resistance (AMR) are forming an alarming alliance: Global warming creates new breeding grounds for resistant bacteria. A serious and very real threat to public health – but not quite the doomsday scenario some might make it out to be, says Prof Sabiha Essack from the University of KwaZulu-Natal in Durban, South Africa.

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Sponsored • Covid-19 management