Laboratory/Pathology • healthcare-in-europe.com

A looming pandemic and the need for physician partnerships to leverage non-invasive testing

Even as we battle one pandemic (Covid-19), we sit on the cusp of another. Europe has one of the highest burdens of chronic liver disease (CLD) in the world, driven largely by alcohol overconsumption, viral hepatitis, and obesity. Furthermore, non-alcoholic fatty liver disease (NAFLD) is increasingly common and is a significant contributor to CLD – especially in people with diabetes, where its…

Fully automated and hematoctrit corrected phosphatidylethanol analysis

The Swiss-based CAMAG DBS Laboratory in collaboration with the Institute of Forensic Medicine in Bern, Switzerland, has developed a novel approach for the fully automated analysis of the direct alcohol marker phosphatidylethanol (PEth) in dried blood spots (DBS). The use of a DBS autosampler with an embedded hematocrit (HCT) scanner combined with an LC-MS system permits analysis of large…

Minimising laboratory errors with automation

Staffing shortages, increased testing volumes and the need to improve turnaround times have led to labs seeking to streamline services. Automation is the key, thanks to the role it plays in minimising time-consuming, costly mistakes. Over recent years, several factors have led to labs struggling to meet demands, facing a need to speed up and streamline services in order to counteract staffing…

Molecular scalable solutions for laboratories of every size

One size does not fit all when it comes to diagnostics. Different diagnostic locations need solutions that meet their needs, whether for on-demand testing in a healthcare setting or a laboratory managing population screening. Finding the right solution can be a challenge especially when the future may change what a laboratory needs, Hologic Inc. reports.

Article • Exploring the potential of IMS

Ion mobility spectrometry: Rapid results from breath analysis

Ion-mobility spectrometry (IMS) offers opportunities for rapid diagnosis and clinical decision-making due to breath analysis. As a rapid separation tool, it has clinical value in the identification and analysis of proteins, peptides, lipids, and glycans. The tool is already used as an exhaled drug monitor for anaesthetised patients. It is flexible, portable and has use for point-of-care testing,…

News • Patient immunity

COVID-19 variants: Rapid test identifies antibody effectiveness

Test could measure patient immunity against multiple COVID-19 variants such as Omicron and Delta at once and inform which synthetic monoclonal antibody to use for treatments.

Article • Mass spec, qPCR and more

Newborn screening: early detection – new diagnostic possibilities

Since its introduction around 60 years ago, the screening of newborn babies for immune, hormone and metabolic disorders has prevented many people from experiencing severe disease progression. The scope of systematic early testing has been significantly enhanced through mass spectrometry (MS). In our interview, Professor Uta Ceglarek, one of the driving forces behind the introduction of MS…

News • Laboratory equipment

MolGen opens new UK office

DNA / RNA extraction technology, system, products and kits for human and animal diagnostics, agriculture, aquaculture, pharma and biotech solutions provider MolGen B.V., announces the recent opening of its UK office. The new office is located at 6th Floor, South Quay Building, 189 Marsh Wall, London, E14 9SH. This expansion will enable the company to meet the rapidly increasing demand for…

News • Finding solutions

$ 1.8 million to stop AMR

Experts predict that without intervention, the problem of multidrug-resistant bacterial infections could be catastrophic by 2050, killing nearly 10 million people each year.

News • Lesions

'Virtual histology' may reduce need for skin biopsies

A 'new technology shows promise by analyzing images of suspicious-looking lesions and quickly producing a detailed, microscopic image of the skin, bypassing several standard steps typically used for diagnosis - including skin biopsy, tissue fixation, processing, sectioning and histochemical staining.

Article • Cancer research

Prostate cancer: Blood tests predict chemotherapy resistance

Researchers have found that regular blood tests can help detect whether prostate cancer patients have resistance to drugs treating the condition. The findings were presented at the National Cancer Research Institute (NCRI) virtual Festival.

Article • Laboratory productivity

Outlook: Lab automation in 2021

Innovations in technology continue to improve clinical laboratory productivity. Total lab automation systems are responding to dramatic growth in internet-driven streamlined processes.

An innovative test for the early diagnosis of Covid-19

Compared to previous SARS and MERS, SARS-CoV-2 became a pandemic due to the high infectivity and different mode of contagion. SARS-CoV-2 spreads more because it is contagious also before symptoms, during incubation phase. No tests to date have been able to find the virus during the pre-symptomatic stage. Stark has developed a new, rapid, non-invasive method "Stark Portable Covid-19 Antigen…

Article • An estimated 800,000 deaths in 2030

Warning of looming global liver disease pandemic

Professor Dina Tiniakos, from the National and Kapodistrian University of Athens, predicts that NASH (Non-alcohol related steatohepatitis) cases will soar worldwide by 2030, with 800,000 liver deaths, costing health economies billions of dollars.

Article • WSI, AI and more

New digital frontiers for nephrology

Digital technology solutions create new opportunities in diagnosis and assessment of renal conditions. With whole slide imaging (WSI), improved workflow and better visualization, such technology already yields a ROI for hospitals and laboratories.

Article • Over-detection and biopsies

New procedures for prostate cancer screening

Organised screening enabling early detection and treatment of prostate cancer can reduce death by an impressive 20%, based on 16 years of findings of over 160,000 men participating in the landmark European Randomised Study of Screening for Prostate Cancer (ERSPC).

Article • NGS solution

Using liquid biopsy to detect recurrent breast cancer earlier

An innovative collaboration has been formed in the UK between academic researchers and industry to develop a rapid integrated liquid biopsy platform for early detection of recurrent breast cancer. Breast cancer specialists Professor Charles Coombes, who is Professor of Medical Oncology at Imperial College London (ICL), and Professor Jacqui Shaw, Head of the Department of Genetics and Genome…

Article • Medicine technology

Medite – Lab equipment

Distributor wanted for Anatomic Pathology Laboratory Devices – Made in Germany! Become Part of the successful international network of Medite Medical GmbH, www.medite.de, info@medite.de, or meet us at booth No. 3H33 in Hall 3!

Article • Accelerating the pace of development

Fighting the pandemic with microfluidic

The Corona pandemic has a major impact on all areas of life. Nearly everyone is affected in some way – in their health, in their jobs, in their entire lives. But there are also notable bright spots. Chief among these effects is the rapid development of vaccines, test kits and, in the future, medicines that are making a significant contribution to overcoming the crisis. Microfluidic components…

Article • Point-of-care testing

Emerging technologies in POCT

Considerable advances in point-of-care testing (POCT) devices are emerging from lab-on-a-chip platforms, innovations in smartphone-based technology and wearable technology. Cloud-based deep learning systems herald a future revolution.

Article • New EU regulation

Lab tests: Watch out! Conflict ahead

In May 2022 a shortage of several lab tests may come as many manufacturers struggle to comply with EU regulation requirements covering in vitro diagnostic medical devices (IVDR, Regulation (EU) 2017/746). Even modified tests and laboratory-developed tests will present a problem for hospitals and labs as explained by Dr Thomas Streichert.

Kugel Medical – UCS-2000-D-E

Digitisation offers great opportunities in pathology to work more efficiently and faster. Used correctly, it reduces the workload for both pathologists and laboratory staff.

News • Whole genome sequencing

Rare disease diagnosis: the huge impact of WGS

Whole genome sequencing (WGS) from a single blood test picks up 31% more cases of rare genetic disorders than standard tests, shortening the ‘diagnostic odyssey’ that affected families experience, and providing huge opportunities for future research.

News • The 'PodoSighter'

AI identifies key indicator of early kidney disease

Researchers have leveraged the power of digital pathology and computational modeling to detect and quantify podocytes, a specialized type of cell in the kidney that undergoes damaging changes during early-stage kidney disease.

News • NGS-based diagnostics

Collaboration on early detection of recurrent breast cancer

Together with Imperial College London (‘Imperial’), molecular diagnostics company DNAe has been awarded a UK Knowledge Transfer Partnership (KTP) by Innovate UK to support development of its next generation sequencing (NGS)-based diagnostic platform for use in cancer monitoring. The KTP program connects innovative businesses with academic experts who can help them deliver their ideas. This…

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