News • Updated diagnostic criteria
Parkinson's: New three-type classification
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
News • Machine learning in sample analysis
Lab-trained pathology AI meets real world: ‘mistakes can happen’
AI models are highly capable in analysing tissue samples – as long as conditions are lab-perfect. Add a little contamination, however, and diagnostic accuracy goes out the window, a new study shows.
News • Focus on autoreactive T lymphocytes
Guillain-Barré Syndrome: researchers find cause
The underlying mechanisms of Guillain-Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.
News • Complication prevention
Placenta organoids help understand pre-eclampsia and pregnancy disorders
Using lab-grown ‘mini-placentas’, researchers from the UK and Switzerland hope to get new insights on dangerous pregnancy complications, such as pre-eclampsia.
Article • Next-generation pathology
Multiplexed staining techniques in the fight against complex diseases
Bringing digital pathology together with novel multiplexed staining techniques may answer key questions about complex diseases. Pathologist Lukas Marcelis, MD, PhD, believes such combinations of technology will have benefits for clinicians and patients and can help unravel some of the mysteries surrounding a range of conditions.
News • Finding therapy-relevant genetics
Leukaemia: AI provides support in diagnostics
Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.
News • Noninvasive fetal screening
Blood test to identify genetic diseases in unborn babies
A research team from Denmark has developed an innovative screening test. With a blood sample from the expectant mother, they can scrutinize all the genes in the fetus.
News • Life sciences and the environment
New award rewards sustainability in the lab
To recognize and support pioneering efforts in life science laboratory settings, EMBO launches its Lab Sustainability Award. Applications can be submitted soon.
News • Raman spectroscopy
Novel bacteria identification methods to speed up disease diagnosis
A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
News • CTC, ctDNA and exosomes in PCa management
Prostate cancer: Blood-based liquid biopsies yield valuable information
US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.
News • Friend and foe in one
Breast cancer: The paradoxical role of white blood cells
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
News • Unexpected behaviour
Pathogens can force their way through the immune defense, new study shows
Breaking & entering – on a minuscule scale: US researchers have shown how some pathogens like Toxoplasma can enter cells using physical force to cause an infection.
News • Impaired immune response
Research identifies being overweight as risk factor for Covid-19 severity
Being overweight – not just being obese – can increase Covid-19 severity. the elevated BMI creates an impaired antibody response to SARS-CoV-2 infection but not to vaccination, new research finds.
News • SCN tumor development
How prostate cancer grows aggressive to evade treatment
In a new study, UCLA researchers demonstrated how small cell neuroendocrine prostate cancer tumor cells can arise from less aggressive prostate tumors.
News • Based on image-based flow cytometry
Rapid test to predict severe Covid-19 infections
Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…
News • Troponin assessment
Blood test aids emergency diagnosis of heart conditions
A high sensitivity blood test can improve diagnosis for one in five patients who have a heart muscle injury, according to new research.
News • WSI-based analysis
AI-driven classification of diffuse gliomas skips molecular testing
Research from Shenzhen proposes an integrated diagnosis model for automatic classification of adult-type diffuse gliomas directly from annotation-free standard whole-slide pathological images.
News • Susceptibility detection in Escherichia coli
How AI can detect antibiotic resistance in 30 minutes
A new deep-learning approach to AMR testing has been shown to detect antimicrobial susceptibility within as little as 30 minutes - significantly faster than current gold-standard approaches.
News • Lab model to find treatments for stroke, dementia
Finding (and fixing) vascular leaks in the brain
Using small blood vessels grown in the lab, researchers discover how vascular leaks leading to dementia and stroke emerge – and how this damage might be fixed.
Article • Infection control
The strain typing technologies of tomorrow
Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.
News • Biosensor
Wireless, handheld device to detect Alzheimer’s and Parkinson’s biomarkers
A team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly.
Sponsored • AutoLumo A1860/A1800
Immunoassay user experience: simple and smart
AutoLumo A1860/A1800 is the new generation of Autobio AutoLumo Series with compact structure and innovative design, providing simpler, smarter and better user experience for small and medium size labs.
Sustainability
Lab-on-a-chip for a low-carbon future
The field of lab-on-a-chip needs to meet important challenges around sustainability. This includes not only the development of smart analytical systems that are able to sense the changes that are occurring within the environment but also, more generally, the mitigation of single-use plastics in analysis and the use of low-power, recyclable microsystem technologies.
PCR
New biomolecular monitoring tool based on lab-on-a-chip for virus detection
Over the last 20 years, the development of lab-on-a-chip (LoC) devices for performing real-time PCR (LoC-PCR) has been an active research field. Now, Italian researchers present their design for a new lab-on-a-chip-PCR device.
Article • Latest advances
Lab-on-a-chip systems in 2023: The micro-lab revolution
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
