Studies

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News • Mammacarcinoma study

Breast cancer: finishing treatment soon after diagnosis increases survival

Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation – are completed more than 38 weeks from the time of diagnosis. The observational study, which included more than 28,000 breast cancer patients registered in the American National Cancer Database, is…

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News • Aerosol propagation study

Covid-19: is it safe to play the trumpet and other wind instruments?

Aerosol generated by playing woodwind and brass instruments is less than that produced when vocalising (speaking and singing) and is no different than a person breathing, new research has found. The findings could be crucial to developing a roadmap for lifting Covid-19 restrictions in the performing arts, which have been significantly restricted since the start of the pandemic.

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News • Digital patients, promising results

Are 'virtual' trials the future of research?

A study involving virtual rather than real patients was as effective in evaluating a medical device used  to treat brain aneurysms, according to new research. The findings are proof of concept for what are called in-silico trials, where instead of recruiting people to a real-life clinical trial, researchers build digital simulations of patient groups, loosely akin to the way virtual…

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News • Fighting the pandemic

90 drugs against Covid-19

Mining the world's most comprehensive drug repurposing collection for Covid-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.

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News • Cardiology & urbanisation

Health and the city: how urban design can promote heart health

Cities harbour a dangerous cocktail of environmental stressors which politicians must tackle to save lives and preserve health. That’s the conclusion of a paper published in European Heart Journal, a journal of the European Society of Cardiology (ESC). “By 2050, three in four people will live in cities, where up to 80% of energy is consumed and 70% of greenhouse gases are emitted,” said…

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News • Vital imaging

Study: contrast MRI after a heart attack could increase survival

A new study from the University of Surrey and University College London has revealed that treatment for heart attacks could be improved thanks to a novel method of evaluating heart function using contrast-based MRI scans. According to the British Heart Foundation, heart and circulatory diseases cause more than a quarter (27 per cent) of all deaths in the UK, which equates to more than 160,000…

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News • Challenges of an aging society

Dementia and gun ownership: an issue that needs regulation

In Sweden, there are over 2 million legally owned firearms. At the same time, up to 150,000 people live with a diagnosis of dementia. In an aging society such as Sweden, legislators will face challenges in gun ownership. A new registry-based observational study by researchers from NVS, Karolinska Institutet, published in the Journal of Alzheimer’s Disease shows a need for strategies for this…

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News • Covid-19 prevention side effects

Rare blood clots after Oxford-AstraZeneca vaccine: study sheds more light

A large study from Denmark and Norway published by The BMJ sheds more light on the risk of rare blood clots in adults receiving their first dose of the Oxford-AstraZeneca Covid-19 vaccine. The findings show slightly increased rates of vein blood clots including clots in the veins of the brain, compared with expected rates in the general population. However, the researchers stress that the risk of…

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News • Discerning good algorithms from bad ones

Medical AI evaluation is surprisingly patchy, study finds

In just the last two years, artificial intelligence has become embedded in scores of medical devices that offer advice to ER doctors, cardiologists, oncologists, and countless other health care providers. But how much do either regulators or doctors really know about the accuracy of these tools? A new study led by researchers at Stanford, some of whom are themselves developing devices, suggests…

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News • After overcoming a Corona infection

Covid-19: Study on long-term antibody protection

Does overcoming a SARS-CoV-2 infection protect against reinfection? The “Rhineland Study”, a population-based study conducted by DZNE in the Bonn area, is now providing new findings in this regard. Blood samples taken last year indicate that an important component of immunity – the levels of specific neutralizing antibodies against the coronavirus - had dropped in most of the study…

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News • Radiology research

Chest CT illuminates COPD mortality risk

Body composition information derived from routine chest CTs can provide important information on the overall health of people with chronic obstructive pulmonary disease (COPD), including their risk of all-cause mortality. This is the result of a new study, published in Radiology. COPD is a group of chronic, progressive lung diseases that affect about 30 million people in the United States alone.…

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News • Mammography support

AI solution may reduce interval breast cancer rates

Medical technology company iCAD, Inc. announced that ProFound AI for 2D Mammography might notably reduce the risk of interval breast cancer, according to a new retrospective analysis. The aim of the study was to determine if adding AI to reading mammography as a supportive tool may help in decreasing the interval cancer rate in population-based organized mammography screening programs in Germany.

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News • Study hints at increased risk

Many Covid-19 patients return to hospital within 140 days

People discharged from hospital after Covid-19 appear to have increased risks of diseases across multiple organs and nearly a third are readmitted to hospital in the following months, according to a new study co-led by researchers at University College London. The study, published in The BMJ, looked at nearly 50,000 people who were discharged from hospital by August last year and compared them to…

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Article • Post-hospitalisation

New study reveals impact of 'Long Covid'

Recovery duration, co-morbidities, mortality, risk groups: A large UK study reports in detail on 'Long Covid'. We spoke with two of the study's co-investigators about why so many patients are still affected after a coronavirus infection.

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News • Malignant brain tumor

Successful test for mutation-specific vaccine against diffuse gliomas

Tumor vaccines can help the body fight cancer. Mutations in the tumor genome often lead to protein changes that are typical of cancer. A vaccine can alert the patients' immune system to these mutated proteins. For the first time, physicians and cancer researchers from Heidelberg and Mannheim have now carried out a clinical trial to test a mutation-specific vaccine against malignant brain tumors.…

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News • Prevalence of depression and anxiety

Covid-19 pandemic impacts mental health worldwide, study finds

A study conducted by Columbia University Mailman School of Public Health researchers reports a high global prevalence of both depression and anxiety during the Covid-19 pandemic. It also shows how the implementation of mitigation strategies including public transportation and school closures, and stay-at-home orders impacted such disorders. Results are published in Psychological Medicine.

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News • Asymptomatic disease spread

Why vaccines alone may not be enough to end the Covid-19 pandemic

Even as vaccines are becoming more readily available, protecting against the asymptomatic and pre-symptomatic spread of the virus (SARS-CoV-2) that causes Covid-19 is key to ending the pandemic, say two infectious disease experts at the Georgetown University Medical Center. In their Perspective, “SARS-CoV-2 Transmission Without Symptoms,” published in the journal Science, they make the case…

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News • New study confirms

Covid-19 vaccines highly effective in nursing homes

In what is believed to be the first published study of Covid-19 vaccine effectiveness in long-term care facilities such as nursing homes, a research team co-led by the Yale School of Public Health found a widely used vaccine is highly successful in preventing infections. Residents of such facilities, particularly those in skilled nursing facilities (SNFs), have experienced disproportionately high…

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News • Delay in treatment for serious illness

Digital Covid-19 'symptom checkers' may do more harm than good

Digital Covid-19 ‘symptom checkers’ may stop some patients from getting prompt treatment for serious illness, suggests an international case simulation study. Both the US and UK symptom checkers consistently failed to identify the symptoms of severe Covid-19, bacterial pneumonia, and sepsis, frequently advising these cases to stay home, the findings indicate. The availability and use of…

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Video • Evaluation of contact-free interaction model

Talking to a 'robotic doc'? Most patients wouldn't mind

In the era of social distancing, using robots for some health care interactions is a promising way to reduce in-person contact between health care workers and sick patients. However, a key question that needs to be answered is how patients will react to a robot entering the exam room. Researchers from MIT and Brigham and Women’s Hospital recently set out to answer that question. In a study…

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Article • Superior in identifying cancers in symptomatic younger women

Breast cancer detection: advantage DBT

Digital breast tomosynthesis (DBT) increases detection of breast cancer in symptomatic women under the age of 60, especially in dense breasts. A large, multi-institutional study conducted in the United Kingdom comparing the sensitivity of full-field digital mammography (FFDM), DBT, and FFDM plus DBT supports findings of two similar published studies, both conducted in China in the same time frame.

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News • Myocarditis, infarction, ischaemia

Many Covid-19 patients leave hospital with heart damage

Around 50% of patients who have been hospitalised with severe Covid-19 and who show raised levels of a protein called troponin have damage to their hearts. The injury was detected by magnetic resonance imaging (MRI) scans at least a month after discharge, according to new findings published in the European Heart Journal. Damage includes inflammation of the heart muscle (myocarditis), scarring or…

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