A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
Researchers from the University of Birmingham have designed and developed a novel diagnostic device to detect traumatic brain injury (TBI) by shining a safe laser into the eye.
Researchers have developed a Raman microscope that can acquire information hundreds of times faster than the conventional method. This could help expand its usefulness in biomedical applications.
Researchers created a special ultrathin sensor, spun from gold, that can be attached directly to the skin without irritation or discomfort. The sensor can measure different biomarkers or substances to perform on-body chemical analysis.
When treating acute infections, health care providers must quickly identify the best antibiotics for fighting the infection. An automated system provides swift, accurate results for determining the best antibiotics at the right dose.
Researchers have developed a noninvasive and reagent-free technique for the efficient detection of COVID-19.
A miniscule area in the brain, known as the locus coeruleus (LC), or blue spot, can help to identify an increased risk of Alzheimer’s disease at a very early stage. The LC is hidden deep in the brainstem and can only be detected with advanced MRI equipment. Heidi Jacobs (Maastricht University/Harvard Medical School) used MRI scans to show that the tau protein can begin to spread in the LC three…
Women remain underrepresented in cardiovascular clinical trials despite guidelines and legal requirements developed almost 30 years ago to ensure broader inclusivity. This lack of representation can limit availability of treatment data on the number one killer of women worldwide—cardiovascular disease.
A team of scientists at Argonne National Laboratory has leveraged artificial intelligence to train computers to keep up with the massive amounts of X-ray data taken at the Advanced Photon Source.
Handheld laser devices that help surgeons quickly spot liver damage could transform transplant procedures, research suggests. The non-invasive technique could provide medical staff with instant data on the health of donor livers and help them to identify which organs are suitable for transplant. If widely adopted, the light-based tool could allow more livers to be transplanted safely and…
Improving the detection of cancerous cells during surgery – this is the goal of the European research project CARMEN. The research institutes Laser Zentrum Hannover e.V. (LZH) from Germany and Multitel asbl from Belgium work together with companies from both countries, JenLab GmbH, Deltatec, and LaserSpec, to develop a novel, compact and multimodal imaging system. This could even allow the…
Higher than normal blood pressure is linked to more extensive brain damage in the elderly, according to a new study published in the European Heart Journal. In particular, the study found that there was a strong association between diastolic blood pressure (the blood pressure between heart beats) before the age of 50 and brain damage in later life, even if the diastolic blood pressure was within…
A method for detecting traumatic brain injury at the point of care has been developed by scientists at the University of Birmingham. Using chemical biomarkers released by the brain immediately after a head injury occurs, researchers are able to pinpoint when patients need urgent medical attention. This saves time in delivering vital treatment and avoids patients undergoing unnecessary tests where…
Researchers studying tissue removed from patients noses during surgery believe they may have discovered the reason why so many people with COVID-19 lose their sense of smell, even when they have no other symptoms. In their experiments they found extremely high levels of angiotensin converting enzyme II (ACE-2) only in the area of the nose responsible for smelling. This Enzyme is thought to be the…
A new machine learning approach classifies a common type of brain tumour into low or high grades with almost 98% accuracy, researchers report in the journal IEEE Access. Scientists in India and Japan, including from Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS), developed the method to help clinicians choose the most effective treatment strategy for individual…
Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer’s disease. Researchers used the “molecular scissors” of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease. The exact causes of Alzheimer’s disease remain unknown, but one of the most well- supported theories focuses on a protein called amyloid beta.…
A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer – and potentially many others. Researchers at the University of Virginia School of Medicine have determined that the supposedly simple cancer, called medulloblastoma, forms an unexpectedly intricate network to drive its growth. Some tumor cells actually turn into another type of…
A novel method of combining advanced optical imaging with an artificial intelligence algorithm produces accurate, real-time intraoperative diagnosis of brain tumors, a new study finds. Published in Nature Medicine, the study examined the diagnostic accuracy of brain tumor image classification through machine learning, compared with the accuracy of pathologist interpretation of conventional…
Researchers have created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer’s and Parkinson’s diseases and other neurological disorders.
More and more people aged 50 and over are suffering from age-related vision disorders. According to the World Health Organization, in four out of five cases they could be avoided if they were diagnosed at an early stage. A European team of scientists, including the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena, has now researched a new method that will enable doctors to better…
Analytically sensitive and specific detection of pharmaceuticals or metabolites in bodily fluids, as well as fast and reliable detection of human pathogens, are major challenges for instrument-based analytics in medical diagnostics. Over the past few years the combination of surface-enhanced Raman spectroscopy (SERS) and microfluidic devices (Lab-on-a-Chip) has emerged as a perfectly suited…
Cognitive impairment associated with cancer, also known as “chemobrain”, has gained recognition as a complication of the disease and its treatment, as it can negatively affect the daily lives of cancer patients and survivors. Chemobrain can be subtle yet persistent, with some cancer patients reporting difficulties related to memory and attention even months after completing their treatment.…
Researchers recently evaluated the accuracy of a technology to monitor blood glucose levels without needles or a finger prick. Early results show that the noninvasive technology measures blood glucose levels as effectively as a finger prick test — without drawing blood.
Recognising malignant tissue remains a tricky task. While today, most patients undergo a biopsy, an invasive procedure where tissue is sampled, stained and assessed, researchers are exploring the potential of optical biopsy, the visual assessment of suspect tissue. The interest in optical biopsy ‘is indeed enormous,’ confirms Dr Thomas Bocklitz, physicist at Friedrich-Schiller University in…
Canadian researchers have invented an intraoperative probe that reliably detects multiple types of tumour cells.
Brain tumor tissue can be hard to distinguish from normal brain during surgery. Neurosurgeons use their best judgment in the operating room but often must guess exactly where the edges of the tumor are while removing it.
An organic dye that can light up cancer cells for two powerful imaging techniques providing complementary diagnostic information has been developed and successfully tested in mice by A*STAR researchers.
Researchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance.
SECARS microscopy, a procedure which is based on quantum effects, with which certain molecules can be monitored virtually in real time, turns out to be a highly sensitive tool for the non-invasive research of the most varied diseases and may supplement the medical diagnosis tools of CT and MRI in the future.
In the genetic material of cancer cells, important growth inhibitors are often switched off by chemical labels in the DNA. Scientists of the German Cancer Research Center and the Ohio State University, USA, discovered in mice that cancer-typical DNA labeling occurs long before the first symptoms of leukemia appear. A test for the genetic label might therefore help to detect a developing cancer at…
The European market for autoimmune disease diagnostics has demonstrated sustained growth due to advances in detection technology and automation, according to a new analysis from Frost & Sullivan (F&S)
While treadmill exercise stress testing is essential to detect cardiovascular disease, gaining clear cardiac images at peak stress level are not easy to gain using standard testing procedures. Now, however, researchers at the Ohio State University Medical Centre have designed equipment to provide high-resolution cardiac images at a critical testing stage, with results in under one hour.
Treadmill exercise testing is a common tool to detect of cardiovascular diseases. But clear images of the working heart are hard to obtain. Now researchers designed MRI equipment to provide high-resolution images of the heart at critical stages.
With 121 high level lectures and 65 published posters, Analytica 2008 - organised by the German Chemical Society (GDCh), the Society for Biochemistry and Molecular Biology (GBM) and the German United Society of Clinical Chemistry and Laboratory Medicine (DGKL) - was again a notable bio-chemistry event.
A team of Stanford University School of Medicine researchers has developed a new type of imaging system that can illuminate tumors in living subjects-getting pictures with a precision of nearly one-trillionth of a meter.