News • Predictive phenotypes
Ovarian cancer: new insights into immune landscapes
Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.
Tumour
News • Position and completeness assessment
3D CT analysis benefits liver tumor ablation
By analyzing CT images with 3D software, researchers demonstrated that small liver tumors can be successfully treated using ablation. This could enable more confident use of ablation treatments.
News • Enhanced imaging and surgical guidance
Fluorescent bacteria light up tumors like a neon sign
A new, bacteria-based contrast agent illuminates tumors like a neon sign during surgery, enabling more precise resection and reducing the risk of recurrence.
News • Proteomic-based score
AI measures tumor ‘stemness’ to predict cancer aggressiveness
A new AI-based tool measures cancer aggressiveness by analyzing the ‘stemness’ of tumors – their similarity to pluripotent stem cells. This could pave the way for new therapies.
News • Targeted drug delivery
Wireless NFC implant delivers chemotherapy deep into tumors
Korean researchers have developed a wireless implantable drug delivery system that enable chemotherapy drugs to penetrate deep into solid tumors—without harming surrounding healthy tissue.
News • Assessment of tumour-infiltrating lymphocytes
Skin cancer: AI assistance helps pathologists identify melanoma
More consistent TIL assessments, more accurate patients' prognoses: New research shows how AI sharpens pathologists' interpretation of tissue samples for malignant melanoma.
News • Tumor microenvironment in nasopharyngeal carcinoma
Towards more personalized treatment of nose cancer
Molecular profiling of over 1,000 nasopharyngeal cancer (NPC) tumours reveals distinct differences in tumour microenvironment of locoregionally advanced NPC, supporting personalised treatment.
News • Dual targeting radioligand
“Smart missile” radiopharmaceutical shows promise against multiple cancers
New research makes a strong case for a new dual-targeting radiopharmaceutical, designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy.
Article • Precision approach through the eye socket
Orbital gateway to surgical removal of brain tumours
Using a keyhole surgery approach, surgeons have found a new way to access previously difficult-to-reach brain regions with faster recovery times. With the help of 3D modelling technology, the neurosurgeons succeeded in removing complex tumours from the cavernous sinus through the eye socket, avoiding complex brain surgery and enabling their patients to make a quicker recovery.
News • CT-based deep learning-driven tool
Liver cancer segmentation and detection with 'SALSA'
Results of a new retrospective study demonstrate the potential of a novel, CT-based deep learning-driven tool to enhance liver cancer diagnosis, treatment planning, and response evaluation.
News • Spatial transcriptomics and ECM imaging
3D insights into the tumor microenvironment
Unprecedented insights into the inner workings of an early-stage lung tumor: An international research team describes a new method for 3D mapping cellular interactions in the tumor microenvironment.
News • Fibroblasts promote tumor growth and spread
Study explores reasons behind high aggressiveness of pancreatic cancer
Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.
News • Systemic cell rewiring
How midkine helps tumours evade immunotherapy
Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.
News • Intrinsic electrical activity drives cancer progression
SCLC: Deciphering the unusual aggressiveness of small cell lung cancer
New research reveals that self-generated electrical activity of small cell lung cancer (SCLC) directly promotes tumor metastasis and progression. This may provide new avenues for future treatments.
News • Circulating tumor DNA analysis
Liquid biopsy helps reduce chemotherapy in colon cancer patients
For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.
News • Field cycling imaging
FCI sees 'previously undetectable' cancer spread
Using a prototype field cycling imager (FCI) scanner to examine breast cancer tissue, scientists distinguish tumour material from healthy tissue with more accuracy than current MRI methods.
News • Aldosterone-producing adenomas
The surprising complexity of adrenal gland tumors
New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.
News • Correlated diffusion imaging
AI makes breast cancer “glow” in MRI images
A new AI-enhanced technique makes breast cancer tissue “glow” on MRI scans. This not only improves breast cancer detection but also can help treat it more effectively, the researchers say.
News • Cell-free tumor DNA analysis
Liquid biopsy to unlock breast cancer treatments
New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.
News • Alteration of immune response
Multiple myeloma: dangerous diversity
When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.
News • Micro Immune Response On chip (MIRO)
Replicating tumours to assess cancer immunotherapy efficacy
Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.
News • Researcher reveals vulnerability
New approach to crack persister tumour cells
Persister cells arise as a result of cancer treatment and are often responsible for tumour relapse. Researchers identified a distinctive feature of persister cells, paving the way for new treatments.
News • Structural research
Researchers use “hallmarks of cancer” to understand tumour growth
“What is a tumour?” Researchers explore tumour architecture as a valuable source of information to understand tumour dynamics and predict its sensitivity to anticancer drugs.
News • Automated tumor detection and segmentation
Deep learning helps detect lung cancer on CT
A new deep learning model shows promise in detecting and segmenting lung tumors. The findings of the study could have important implications for lung cancer treatment.
News • Machine learning prediction
AI opens non-surgical way to detect brain cancer metastasis
Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients’ cancer without aggressive surgery.
