Health chiefs are failing to investigate a clear pattern of rising death rates and worsening health outcomes in England and Wales, argue experts in The BMJ today. Lucinda Hiam at the London School of Hygiene & Tropical Medicine and Danny Dorling at the University of Oxford say weekly mortality figures show 10,375 additional deaths (a rise of 12.4%) in England and Wales in the first seven…
A new imaging technology to grade tumour biopsies has been developed by a team of scientists led by the Department of Physics and the Department of Surgery and Cancer at Imperial College London. Publishing their results in the journal Convergent Science Physical Oncology, they describe how their new method promises to significantly reduce the subjectivity and variability in grading the severity…
For the first time, scientists at Wake Forest Baptist Medical Center have been able to measure a specific molecule indicative of osteoarthritis and a number of other inflammatory diseases using a newly developed technology. This preclinical study used a solid-state nanopore sensor as a tool for the analysis of hyaluronic acid (HA). HA is a naturally occurring molecule that is involved in tissue…
Researchers led by Professor Stefan Pfister from the "Hopp Children's Cancer Center at the NCT Heidelberg" (KiTZ) have been able to draw an extremely detailed molecular map of childhood cancers. In close collaboration with the German Cancer Consortium (DKTK) and the Society for Pediatric Oncology and Hematology (GPOH), they screened almost 1,000 tumor samples from 24 cancer types for…
Scientists at Columbia University’s Mailman School of Public Health developed a system to accurately predict the geographic spread of seasonal influenza in the United States up to six weeks ahead of time.
Holography, like photography, is a way to record the world around us. Both use light to make recordings, but instead of two-dimensional photos, holograms reproduce three-dimensional shapes. The shape is inferred from the patterns that form after light ricochets off an object and interferes with another light wave that serves as a reference. When created with X-ray light, holography can be an…
High levels of vitamin D may be linked to a lower risk of developing cancer, including liver cancer, concludes a large study of Japanese adults published by The BMJ today. The researchers say their findings support the theory that vitamin D might help protect against some cancers. Vitamin D is made by the skin in response to sunlight. It helps to maintain calcium levels in the body to keep bones,…
In standard settings, the analysis of each DNA modification requires a carefully optimised assay that runs under specific conditions. This increases cost and labour and is a severe limitation to throughput. Now, however, researchers at Stanford University and the Technical University of Denmark have come up with a new method that will enable doctors to make a more precise diagnosis, prognosis and…
Together with three other neuroscientists Professor Christian Haass, speaker of the German Center for Neurodegenerative Diseases (DZNE) Munich site and Professor at the Ludwig-Maximilians-University of Munich, receives the world’s most valuable prize for brain research. The 2018 Brain Prize, awarded by the Lundbeck Foundation in Denmark, is worth one million Euros. Awarded annually, it…
A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. The major difference from today’s classification is that type 2 diabetes actually consists of several subgroups, the results indicate. “This is the first step towards personalised treatment of diabetes”, says physician and diabetes expert Leif Groop.
Eating fish at least once a week or eating fish one to three times per month in addition to taking daily fish oil supplements may be associated with a reduced risk of multiple sclerosis (MS), according to a preliminary study that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018. These findings suggest that the omega-3 fatty acids…
Cell-based biosensors can simulate the effect of various substances, such as drugs, on the human body in the laboratory. Depending on the measuring principle, though, producing them can be expensive. As a result, they are often not used. Cost factors for sensors that perform measurements electrically are the expensive electrode material and complex production. Fraunhofer scientists are now…
People who are frequently exposed to diesel exhaust while on the job may have a higher risk of amyotrophic lateral sclerosis (ALS), and that risk may increase with greater exposure, according to a preliminary study released that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018. “There is some suggestion from previous studies of…
With support from a research grant from the Academy of Architecture for Health Foundation, a West Virginia University researcher is leading a study that will help address the functional complexity of large hospitals. Shan Jiang, assistant professor of landscape architecture in the School of Design and Community Development, and her research team will utilize immersive virtual reality technologies…
What effect does a particular cancer medicine or radiation therapy have on patients? To find out, physicians use CT images to determine whether a tumor’s size changes during the course of treatment. In the PANTHER project, a joint team of experts aims at gaining further valuable information from these images. In the future, doctors will be able to find out at an early stage whether a cancer…
Does life really begin at 40? Is 50 the new 30? For people in these age groups, the answer appears to be yes. But for young adults in their teens and early 20s, turning 50 equates to hitting old age. A new study of more than a half-million Americans led by a Michigan State University scholar shows just how skewed views of aging can be – particularly among the young. The findings come as people…
Testing cancer drugs on miniature replicas of a patient’s tumour could help doctors tell in advance which treatments will work, a major new study reports. The exciting new technique involves growing ‘mini tumours’ from biopsy samples – and could help end reliance on trial and error in selecting cancer treatments for patients where genetic tests are not predictive of response. Researchers…
The mass pursuit of a conspicuous suspect in Alzheimer’s disease may have encumbered research success for decades. Now, a new data analysis that has untangled evidence amassed in years of Alzheimer’s studies encourages researchers to refocus their investigations. Heaps of plaque formed from amyloid-beta that accumulate in afflicted brains are what stick out under the microscope in tissue…
To date, examining patient tissue samples has meant cutting them into thin slices for histological analysis. This might now be set to change – thanks to a new staining method devised by an interdisciplinary team from the Technical University of Munich (TUM). This allows specialists to investigate three-dimensional tissue samples using the Nano-CT system also recently developed at TUM. Tissue…
Tears may hold clues to whether someone has Parkinson’s disease, according to a preliminary study released that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018. “We believe our research is the first to show that tears may be a reliable, inexpensive and noninvasive biological marker of Parkinson’s disease,” said study…
In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer. The new findings represent one more step toward…
Parents who allow their young children to occasionally sip and taste alcohol may be contributing to an increased risk for alcohol use and related problems when those kids reach late adolescence, according to a new study by a University at Buffalo psychologist. The findings contradict the common belief that letting kids sip and taste alcoholic drinks is harmless, and might even help to promote…
One of the biggest challenges in treating prostate cancer is distinguishing men who have aggressive and potentially lethal disease from men whose cancer is slow-growing and unlikely to metastasize. For years, prostate-specific antigen (PSA) level, cancer grade and tumor stage have been used to sort prostate cancer patients into risk groups established by the National Comprehensive Cancer Network.…
The television drama, Grey’s Anatomy, may be giving viewers a false impression of the realities of trauma care, including the speed at which patients recover after sustaining serious injuries, finds research published in the online journal Trauma Surgery & Acute Care Open. Unrealistic expectations of healthcare may be important in an era in which patient satisfaction is a key component of…
Cell division is an intricately choreographed ballet of proteins and molecules that divide the cell. During mitosis, microtubule-organizing centers (MTOCs) assemble the spindle fibers that separate the copying chromosomes of DNA. While scientists are familiar with MTOCs’ existence and the role they play in cell division, their actual physical structure remains poorly understood. Shruthi…
