Article • Awareness
Focus on cancer
From solid tumors to metastatic carcinomas and leukemia: cancer is among the most common causes of death. Keep reading for latest developments in early detection, staging, therapy and research.
Tumour
News • Glioblastoma
Blood test for brain tumors possible
Researchers at the University of Sussex are one step further to developing a blood test capable of diagnosing the most aggressive form of brain tumour.
News • Without causing neurological damage
Injections of zika virus destroys brain tumors
In both the mice and organoids, cytokines suppressed tumor growth after treatment, and defense cells migrated to the brain region affected by the tumor, alerting the immune system to its existence.
News • Multiple tumor tissue biomarkers
MOSAICA: next-generation biopsy technology
A new biopsy tool will enable scientists and clinicians to simultaneously profile many biomarkers in cells and tissues.
Article • Cancer mortality study
Does ethnicity affect brain tumour survival?
New research has pinpointed ethnicity as a potential factor in brain tumour survival. A UK study showed that white British people who have been diagnosed with a malignant primary brain tumour appear to have an increased one-year mortality than patients from at least four other ethnic groups.
News • Oncology
New blood test identifies if a patient has cancer
Researchers outline a new minimally invasive and inexpensive blood test that can identify cancer in patients with non-specific symptoms and whether these cancers have metastasised in the body.
News • Oncology
Tumor blood vessel a target to treat glioblastoma?
A novel protein regulator of tumor angiogenesis, TMEM230, was recently characterized by researchers to have a role in tumor development and vascularization, with potential as a target for anti-tumor therapy in difficult-to-treat cancers such as glioblastoma.
News • Lesions
'Virtual histology' may reduce need for skin biopsies
A 'new technology shows promise by analyzing images of suspicious-looking lesions and quickly producing a detailed, microscopic image of the skin, bypassing several standard steps typically used for diagnosis - including skin biopsy, tissue fixation, processing, sectioning and histochemical staining.
Article • Mass spectrometry goes handheld
A pen to pin down the fringes of cancer
Mass spectrometry – a powerful tool for analysing the molecular composition of a tissue sample – is invaluable during cancer surgery. However, mass spectrometers are complex and unwieldy, and certainly a poor fit for an operating room (OR). To create a bridge between the lab and OR, Professor Livia S Eberlin, from Baylor College of Medicine, has developed a very special ‘pen’.
News • Ductal adenocarcinoma
Pancreatic cancer ‘priming’ may make chemotherapy more effective
A new approach to ‘prime’ the tumour environment may improve how effective chemotherapy is for pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer. In preclinical models, a team at the Garvan Institute of Medical Research could enhance the tumours’ response to chemotherapy by reducing the stiffness and density of the connective tissue known as the stroma,…
News • Metastasis research
Tissue-engineered prostate tumours shed light on cancer spread
Research led by the Queensland University of Technology (QUT) on the interaction between prostate cancer cells and the tumour microenvironment has shed more light on the propensity of some types of prostate cancer to metastasize to bone more readily than other types.
News • Tumor growth stopped in mice
Antidepressants show promise in cancer growth inhibition
Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappeared completely, researchers at the University of Zurich (UZH) and University Hospital Zurich (USZ) have found. Their findings will now be tested in…
News • Patient response testing
New method predicts which cancer therapies work (and which don't)
A new technology that can study which therapies will work on patients with solid cancerous tumours has been developed by scientists at University College London (UCL). Researchers say the tool, which can rapidly test tumorous tissue against different treatments, such as chemotherapy, immunotherapy or radiotherapy, could be used by clinicians to pinpoint the best therapy for a particular patient.
News • New cause for tumor spread found
Blood vessels produce growth factor that promotes metastases
Scientists from the German Cancer Research Center (DKFZ) and the Medical Faculty Mannheim, Heidelberg University, have identified a new growth factor produced by blood vessels that enables tumor cells to metastatically colonize organs.
News • Functional diagnostics
New assay could advance personalized cancer treatment
A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.
News • Tumor environment
When cancer cells turn acidic to survive
For the first time, researchers at the Norwegian University of Science and Technology (NTNU) have shown how cancer cells reprogram themselves to produce lactic acid and to tolerate the acidic environment that exists around tumors. The finding could lead to a whole new direction for treating cancer. The breakthrough is the result of more than 13 years of work. The next step in research could…
News • Brain cancer
Malignant Gliomas: Novel therapy may improve survival
A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial.
News • Identificación de mutaciones tumorales
El aprendizaje automático impulsa la medicina personalizada del cáncer
El laboratorio de Genómica Biomédica del IRB Barcelona (Institute for Research in Biomedicine) ha desarrollado un método computacional que identifica las mutaciones causantes del cáncer para cada tipo de tumor.
News • Tool to identify tumour mutations
Machine learning fuels personalised cancer medicine
The Biomedical Genomics laboratory at the Institute for Research in Biomedicine (IRB) Barcelona has developed a computational tool that identifies cancer driver mutations for each tumour type. This and other developments produced by the same lab seek to accelerate cancer research and provide tools to help oncologists choose the best treatment for each patient. The study has been published in the…
News • Cancer 'avatars'
Predicting immunotherapy outcomes with mini tumours
Miniature tumours in the lab are able to predict whether the corresponding real-life patients will benefit from immunotherapy. “We’ve solved a major problem many scientists had been facing: preserving a tumours original composition and structure outside of the patient in the lab”, says cancer researcher Daniela Thommen.
News • Tumour development research
New bladder cancer model could lead to better treatment
Uppsala University scientists have designed a new mouse model that facilitates study of factors contributing to the progression of human bladder cancer and of immune-system activation when the tumour is growing. Using this model, they have been able to study how proteins change before, while and after a tumour develops in the bladder wall. The study has now been published in the scientific…
News • Neoadjuvant chemotherapy
Breast cancer: New test predicts therapy success
In a collaboration with the Faculty of Statistics at TU Dortmund and the University Medical Center in Mainz, a research team at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) has developed a test that can be used to predict the success of therapy for breast cancer. Breast cancer is one of the most common tumour diseases worldwide. One in eight women will…
News • Non-invasive
LUCA device is ready for better thyroid cancer screening
The EU-funded consortium Laser and Ultrasound Co-analyzer for Thyroid Nodules (LUCA) has developed a non-invasive, low-cost device that brings a new solution for thyroid cancer screening.
News • Aggressive brain tumour
Glioblastoma can be tricked into 'repairing' itself
Scientists at the University College London (UCL) have made a ‘surprising’ discovery that glioblastoma, an aggressive brain cancer, mimics normal brain repair in white matter, which leads to the tumour becoming less malignant. In the study on mice, funded by Cancer Research UK and published in Nature Communications, researchers used these novel findings to identify drugs which could be used,…
News • Malignant brain tumor
Successful test for mutation-specific vaccine against diffuse gliomas
Tumor vaccines can help the body fight cancer. Mutations in the tumor genome often lead to protein changes that are typical of cancer. A vaccine can alert the patients' immune system to these mutated proteins. For the first time, physicians and cancer researchers from Heidelberg and Mannheim have now carried out a clinical trial to test a mutation-specific vaccine against malignant brain tumors.…
