Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…
AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.
Gene alterations in biliary tract cancer offer potential targets for current or future precision therapies. This is demonstrated by a new study from Vienna.
Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).
Autism spectrum disorder (ASD) is a developmental disorder associated with difficulties in interacting with others, repetitive behaviors, restricted interests and other symptoms that can impact academic or professional performance.
A study led by Dr. Ryosuke Tsuchimochi and Professor Jun Takahashi examined the effects of combining cell transplantation and gene therapy for axonal outgrowth in the central nervous system.
A research team from DGIST develops an electronic medicine technology that restores abnormal protein behavior, the cause of Charcot-Marie-Tooth Disease (CMT).
For pancreatic cancer, the effect of immunotherapy is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this sex difference.
Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).
Carestream Health is funding and participating in an innovative pilot with OSIC that could lead to radiographs providing an early window into manifestations of IPF that are currently undetected.
Using imaging guidance, interventional radiology – a sub-discipline of diagnostic imaging – allows targeted and ultraprecise diagnostic and therapeutic procedures without anesthesia and without large incisions. Nevertheless, surgery continues to be widely considered the procedure of choice, making interventional radiology the Cinderella of the discipline. Professor Dr. Marco Das, Medical…
Scientists from Japan demonstrated, for the first time, a successful chemogenetic suppression of widespread epileptic seizures in macaque monkeys. Their findings represent an essential step towards clinical trials, and effective treatment for patients with severe epilepsy.
A new study confirms that haematopoietic stem cell transplantation can be used to cure patients with HIV infections. This third successful case gives new insights into the underlying processes.
Scientists are developing a new kind of light-activated cancer treatments. This would work by switching on LED lights embedded close to a tumour, which would then activate biotherapeutic drugs.
The newly founded UK Focused Ultrasound Foundation is dedicated to advancing the development and adoption of the technology, which can be used to non-invasively treat tissue deep in the body.
Evidence that radioembolization, a trans-arterial therapy, is safe and stops disease progression in metastatic breast cancer is increasing, a prominent American interventional radiologist showed at the Spectrum conference in Miami.
A new study from Spain has demonstrated the efficiency of an ultrasound radiation-based therapy on the inhibition of cancer cell motion in pancreas cancer models.
Both high and low dose exercise therapy have beneficial effects in patients with symptomatic knee osteoarthritis. However, a new Swedish study shows that, sometime, more can indeed be more.
High-intensity focused ultrasound (HIFU) ablation is a noninvasively treatment for benign thyroid nodules that are causing distress to patients. Brian H. H. Lang, MD, Clinical Professor in the Department of Surgery at the University of Hong Kong, and chief of the Division of Endocrine Surgery at Queen Mary Hospital, is a preeminent investigator, proponent, and pioneer of this technique. He…
Focused ultrasound (FUS) ablation is an emerging treatment for breast tumours. Its use was highlighted in an October webinar focused on emerging immunotherapy research and breast cancer.
Immunotherapy prior to surgery is surprisingly effective for patients with a certain type of colorectal cancer (dMMR/MSI-H CRC). These new study results contrast current treatment regimens.
The American Academy of Pediatrics has issued its first comprehensive guideline on the evaluation and treatment of children and adolescents with obesity, marking an end to previous recommendations.
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research.
New advanced therapies can alleviate or cure chronic diseases. But medical progress, such as the gene editing tool CRISPR, raises the question of how rights should be protected and balanced.
Scientists managed to identify and kill breast cancer cells that evade standard treatments in a study in mice. The is a step towards the development of new treatments to prevent relapse in patients.