Clinical routine would be inconceivable without MR Imaging. Without exposure to radiation, doctors can make a patient’s organs and tissue structures clearly visible. However, pathological changes in the early stages, degenerated cells or small areas of inflammation, have so far remained almost invisible on these images. In 2014, for the first time, a team of cell biologists, chemists and…
In breast cancer care each patient receives personalised, highly effective diagnosis and treatment procedures. In breast diagnostics this mainly revolves around new MRI scanning procedures that allow the quantification of biological and physiological processes on a cellular and molecular level.
Women with metastatic breast cancer know they have a slim chance of long-term survival. The question is whether personalised therapy could extend their lives. Report: Cynthia E Keen
A new extracorporeal nanotech device addresses the root cause of sepsis by removing pathogens and endotoxins simultaneously from blood even before their identification – this genetically engineered mannose-binding lectin protein can also latch on to the Ebola virus... Report: Cynthia E Keen
Two things that radiologists resist – structured reporting and (computer-assisted) quantification – are the very things that Gabriel Krestin believes are essential to advance diagnosis in the brave new world of omic-medicine that is emerging.
In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.
New imaging biomarkers are helping radiology to play a greater role in new drug developments.
EKF Diagnostics, worldwide manufacturer of point-of-care diagnostic tools, organ injury biomarkers and assays, has announced the launch of a new division to focus on molecular and companion diagnostics.
MRI has become the gold standard for many indications in cardiac imaging, apart from imaging the coronary arteries. For function and morphology assessment, MRI is the leading technology. A further advance into as yet unknown territory is myocardial imaging aided by one of the first integrated 3-Tesla PET/MR systems currently used at the Institute of Radiology, Essen University Hospital,…
‘We need an ECG for Sepsis,’ urged Professor Konrad Reinhart during this year’s Anaesthesiology and Intensive Care Medicine (HAI) Congress in Berlin.
Dr Peter Choyke, Chief of the Molecular Imaging Programme at the National Cancer Institute in Bethesda, USA, believes that new tracers will have an evolving role to play and represent an exciting development in the imaging of cancers.
Although most nuclear medical examinations using SPECT (single photon emission computed tomography) take place beyond hospitals, two to three times more SPECT exams than PET-CT exams are carried out within hospitals.
UK researchers are working on a new MRI technique called hyperpolarised MRI – or Dynamic Nuclear Polarisation (DNP) – that can utilise more of the available nuclei than traditional MRI, helping to overcome some of its limitations by increasing sensitivity 10,000-fold or more. DNP is part of a longer-term aim to improve cancer mortality with the help of novel cancer imaging tools.
Radiology constantly evolves. There are technical advances in terms of the capabilities of various modalities, greater clarity from contrast agents that are also safer for patients, and innovation in techniques that gains even greater performance from existing equipment, or enables further development.
GE Healthcare announced today its plans to dedicate $1 billion of its total R&D budget over the next five years to expand its advanced cancer diagnostic and molecular imaging capabilities, as well as its world-class technologies for the manufacture of biopharmaceuticals and for cancer research.
2011 brought a second year for European and US scientists to meet up at the Annual Scientific Symposium on Ultra High Field Magnetic Resonance, held at the Max Delbrück Centre for Molecular Medicine Berlin-Buch (MDC), Germany, to present and discuss their recent findings. Along with technical improvements, the main issues of the one-day gathering were cardiac, cerebral and molecular MR imaging.…
PredictAD is an EU-funded research project that develops objective and efficient methods for enabling earlier diagnosis of Alzheimer's disease. Diagnosis requires a holistic view of the patient combining information from several sources, such as, clinical tests, imaging and blood samples.
Research introduced at SNM’s 58th Annual Meeting may lead to much-needed cardiovascular disease screening for diabetic patients at risk of ischemic heart disease, a disorder marked by significantly reduced blood flow in the heart. Ischemia of the myocardium, or cardiac muscle, can signal diminished oxygenation of the heart tissue and trigger a heart attack if left untreated.
Biomarkers – mainly defined as surrogates serving as indicators for specific biological states – play an ever-increasing role in neuroscience and especially in the management of multiple sclerosis, scientists reported today at the 21st Meeting of the European Neurological Society (ENS) in Lisbon. In analyzing gene expression patterns, immunological changes and imaging abnormalities,…
ENCITE experts are very pleased to meet the imaging community at the European Molecular Imaging Meeting (EMIM) 2011 in Leiden/NL. The congress brings together top European scientists from various disciplines working in diverse fields of molecular imaging to discuss latest research discoveries and possible translations into medical practice.
Medical imaging has recently advanced so rapidly that it should halt. Applying more power to computed tomography (CT) and magnetic resonance imaging (MRI) scanners is becoming too dangerous for patients and healthcare workers. Magnets for the next-generation MRIs are so powerful that they must be moved to a separate building on hospital campuses, while CT radiation levels have risen to alarming…
Although developments in molecular imaging still do not reach the high expectations placed upon them, the change in imaging is very obvious. Having been limited to the imaging of morphology, nowadays information on tissue characteristics, blood vessels or the metabolic behaviour of tumours provide many more insights, for example into response behaviour.
Breast cancer can develop very differently in different women. Researchers in Norway are improving breast cancer diagnostics and treatment by identifying the various tumour types. The objective is to find out as much as possible about the various tumour types so that each patient can receive precisely the right treatment at the right time.
Molecular imaging (MI) is reported as an increasingly important diagnostic field for radiologists to focus on. However, molecular imaging should not be considered a new discipline that only adds to today’s clinical practice, or might even replace the traditional, more morphology-oriented diagnosis. Rather, the whole diagnostic concept should be re-considered.
Molecular imaging (MI) appears as an unavoidable challenge for the future of imaging, because MI is able to characterise cellular and molecular processes and will serve as a guide for new targeted or personalised therapies. However, MI appears as hype for many radiologists because it is too far from clinical practice. In reality, MI is already part of clinical practice using PET and targeted…